Agostinho Albérico Rodrigues de Carvalho (FF1C-FC2E-2E27)

Curriculum Vitae

Agostinho Albérico Rodrigues de Carvalho

Agostinho Carvalho graduated in 2003 in Biology from the University of Minho and received a PhD in Health Sciences from the same University in 2008. Between 2009 and 2012, he developed postdoctoral studies on the genetic basis of susceptibility to fungal infection at the Life and Health Sciences Research Institute (ICVS) of the University of Minho, and the University of Perugia, Italy, in the lab of Luigina Romani. In 2012, he became an Assistant Researcher at the Department of Experimental Medicine of the University of Perugia, where he further developed his interests in fungal immunology and immunogenetics until 2014. Later that year, he became an Assistant Researcher (FCT Investigator) and returned to ICVS, where he consolidated his research team. Since 2019, he has been a Principal Investigator (with Habilitation since 2023) at ICVS. He was also nominated Vice-Director of ICVS in 2023. His research activity is focused on the elucidation of the effects of interindividual genetic variation on molecular and cellular processes of immunity and inflammation, and the translation of this information into new and personalized approaches for the prognosis, diagnosis, and therapy of infectious and inflammatory diseases. These aims are being addressed by a multidisciplinary team that combines basic scientists and clinical experts with different degrees of specialization, and that resorts to advanced cellular and animal models of disease and human patients enrolled in national and international consortia. The team is also engaged in collaborations with several international labs on immunology, functional genomics, and the biology of infectious and inflammatory diseases. His track record includes 141 publications in international peer-reviewed journals (>6,600 citations and h-index=40, ISI Web of Knowledge; March 2024), 1 book and 9 book chapters, and a patent on fungal diagnostics. Selected publications include senior authorship of papers in Lancet Respir Med 2022, Nat Microbiol 2022, Am J Respir Crit Care Med 2022, N Engl J Med 2014, Nat Commun 2020, and JACI 2017, besides relevant collaborations in Lancet Microbe 2024 and 2022, Cell Host Microbe 2023, Nature 2018, Nat Microbiol 2018, Immunity 2013, Cell Metab 2016, and Nat Commun 2021 and 2018. He has been supported by several funding agencies, e.g., H2020, "la Caixa" Foundation, Fundação para a Ciência e a Tecnologia (FCT), European Society for Clinical Microbiology and Infectious Diseases (ESCMID) and contracts with the industry, e.g., Gilead, Mérieux. He has supervised 10 postdoctoral researchers and 12 PhD students, besides multiple MSc and undergraduate students. He is the Chief Specialty Editor for Medical Mycology in Frontiers in Fungal Biology and an editorial board member for Infection and Immunity and Microbiology Spectrum. He has been an ad-hoc reviewer for more than 70 journals and several funding agencies, including the European Commission (e.g., ERC, H2020, MSCA), Wellcome Trust, Agence Nationale de la Recherche (ANR), Ministero dell'Istruzione e del Merito (MIUR), Israel Science Foundation (ISF), and FCT. Because of his contributions to the field, he has received over 70 invitations to speak/chair at established international meetings, and several awards, including the Jon J. van Rood award for outstanding contributions in immunogenetics. He is an elected Fellow of the European Confederation of Medical Mycology (ECMM).

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Identification

Personal identification

Full name: Agostinho Albérico Rodrigues de Carvalho

Citation names

Carvalho, Agostinho

Author identifiers

Ciência ID: FF1C-FC2E-2E27
ORCID iD: 0000-0001-8935-8030
Google Scholar ID: -BRrhZ8AAAAJ&hl
Researcher Id: D-2667-2009
Scopus Author Id: 16303300600

Email addresses

agostinhocarvalho@med.uminho.pt (Professional)

Telephones

Telephone

253604811 (Professional)

Addresses

Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus de Gualtar, 4710-057, Braga, Braga, Portugal (Professional)

Websites

https://www.researchgate.net/profile/Agostinho_Carvalho (Professional)
https://publons.com/researcher/1204902/agostinho-carvalho (Professional)

Knowledge fields

Medical and Health Sciences - Health Sciences - Infectious Diseases
Medical and Health Sciences - Basic Medicine - Human Genetics
Medical and Health Sciences - Basic Medicine - Immunology
Medical and Health Sciences - Clinical Medicine - Hematology

Languages

Language	Speaking	Reading	Writing	Listening
Portuguese (Mother tongue)
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
Spanish; Castilian	Intermediate (B1)	Advanced (C1)	Beginner (A1)	Intermediate (B1)
French	Beginner (A1)	Intermediate (B1)	Beginner (A1)	Beginner (A1)
Italian	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)

Education

	Degree	Classification
2023 Concluded	Habilitation in Health Sciences (Título de Agregado) Universidade do Minho Escola de Medicina, Portugal	Approved
2008 Concluded	PhD in Health Sciences - Biological and Biomedical Sciences (Doutoramento) Universidade do Minho Escola de Medicina, Portugal "Management of fungal infections: diagnosis and human genetic susceptibility" (THESIS/DISSERTATION)	Approved
2003 Concluded	BSc in Applied Biology (Licenciatura) Universidade do Minho Escola de Ciencias, Portugal "Use of the yeast Saccharomyces cerevisiae as a model organism in the study of Batten disease" (THESIS/DISSERTATION)	15

Affiliation

Science

	Category Host institution	Employer
2019/05 - Current	Principal Investigator (Research)	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2015/03 - 2019/05	Auxiliary Researcher (Research)	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2012/12 - 2014/06	Auxiliary Researcher (Research)	Universita degli Studi di Perugia, Italy
	Università degli Studi di Perugia Dipartimento di Medicina Sperimentale, Italy
2009/01 - 2012/12	Postdoc (Research)	Universita degli Studi di Perugia, Italy
	Università degli Studi di Perugia Dipartimento di Medicina Sperimentale, Italy
2004/02 - 2008/07	Researcher (Research)	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2006/06 - 2006/10	Visiting Researcher (Research)	Universita degli Studi di Perugia, Italy
	Università degli Studi di Perugia Dipartimento di Medicina Sperimentale, Italy
2002/09 - 2003/07	Research Trainee (Research)	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Teaching in Higher Education

	Category Host institution	Employer
2014/05 - Current	Lecturer (University Teacher)	Universidade do Minho Escola de Medicina, Portugal
	Universidade do Minho Escola de Medicina, Portugal
2013/02 - 2014/05	Invited Assistant Professor (University Teacher)	Universita degli Studi di Perugia, Italy
	Università degli Studi di Perugia Dipartimento di Medicina Sperimentale, Italy
2011/10 - 2012/02	Invited Assistant Professor (University Teacher)	Universidade do Minho Escola de Medicina, Portugal
	Universidade do Minho Escola de Medicina, Portugal
2003/10 - 2007/02	Tutor (University Teacher)	Universidade do Minho Escola de Medicina, Portugal
	Universidade do Minho Escola de Medicina, Portugal

Projects

Grant

	Designation	Funders
2024 - Current	Metabolic regulation of granulomatous inflammation by tryptophan catabolism 2023.03013.BD Supervisor Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2023 - Current	Metabolic control of immune cell function during fungal infection 101130795 Supervisor Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions Ongoing
2023/01 - 2026/12	Metabolic circuits of immune regulation and function during fungal infection 2022.12062.BD Supervisor Universidade do Minho Instituto de Investigacao em Ciencias da Vida e Saude, Portugal	Fundação para a Ciência e Tecnologia (FCT) Ongoing
2018/09 - 2023/04	Innate regulation of antifungal immunity in chronic obstructive pulmonary disease SFRH/BD/141127/2018 Supervisor Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e Tecnologia (FCT) Concluded
2023 - 2023	The genetic architecture of the immune response to Aspergillus fumigatus: from biological understanding to therapeutic intervention 200523/2022-8 Supervisor Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Conselho Nacional de Desenvolvimento Científico e Tecnológico Concluded
2018/09 - 2022/12	Metabolic regulation of antifungal immunity through the mevalonate pathway SFRH/BD/136814/2018 Supervisor Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e Tecnologia (FCT) Concluded
2019/05 - 2021/01	The Genomic Landscape of the Individual Host Response to Fungal Disease CEECIND/03628/2017 Principal investigator Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e Tecnologia (FCT) Concluded
2015/03 - 2019/05	The Role of Inflammasome-Autophagy Crosstalk in Fungal Infection IF/0735/2014 Principal investigator Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e Tecnologia (FCT) Concluded
2009/01 - 2012/11	SUSCEPTIBILITY TO INFECTIOUS DISEASE IN HAEMATOPOIETIC STEM CELL TRANSPLANTATION: THE ROLE OF POLYMORPHISMS IN THE TOLL-LIKE RECEPTOR SIGNALLING PATHWAYS SFRH/BPD/46292/2008 Post-doc Fellow Università degli Studi di Perugia Dipartimento di Medicina Sperimentale, Italy Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e Tecnologia (FCT) Concluded
2004/02 - 2008/01	Management of fungal infections: diagnosis and human genetic susceptibility SFRH/BD/11837/2003 PhD Student Fellow Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e Tecnologia (FCT) Concluded

Contract

	Designation	Funders
2021/01 - Current	Host-microbiome interactions in the quest for Fibrosing ILD Biomarkers that Rule Acceleration (FIBRA-Lung) PTDC/MEC-RES/0158/2020 Researcher Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2021/01/01 - 2025/12/31	ICVS/3B¿s - Laboratório Associado, Instituto de Ciências da Vida e da Saúde / Grupo de Investigação em Biomateriais, Biodegradaveis e Biomiméticos LA/P/0050/2020 Universidade do Minho, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2023/01 - 2025/12	Metabolic control of immune cell function in respiratory fungal disease 2022.06674.PTDC Co-Principal Investigator (Co-PI) Universidade do Minho Instituto de Investigacao em Ciencias da Vida e Saude, Portugal	Fundação para a Ciência e Tecnologia (FCT) Ongoing
2022/10 - 2025/09	Whole-systems analysis of the microbiome-metabolome crosstalk for biomarker discovery and therapy of respiratory fungal diseases LCF/PR/HR22/00879 Researcher Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	"la Caixa" Foundation Ongoing
2022/01 - 2024/12	Immunometabolic regulation of granulomatous inflammation in sarcoidosis PTDC/MED-OUT/1112/2021 Principal investigator Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e Tecnologia (FCT) Ongoing
2020/01 - 2024/12	HDM-FUN: Host-directed medicine in invasive fungal infection 847507 Researcher Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	EU Framework Programme for Research and Innovation Health Demographic Change and Wellbeing Ongoing
2023/01 - 2024/06	Tracking brain tumors through their exosomes: a WNT6-driven approach 2022.05143.PTDC Researcher Universidade do Minho Instituto de Investigacao em Ciencias da Vida e Saude, Portugal	Fundação para a Ciência e Tecnologia (FCT) Ongoing
2023/01 - 2024/06	Elucidating the role of sialidase-1 in the severity of feline sporothricosis caused by Sporothrix brasiliensis 2022.03348.PTDC Researcher Universidade do Minho Instituto de Investigacao em Ciencias da Vida e Saude, Portugal	Fundação para a Ciência e Tecnologia (FCT) Ongoing
2020/10 - 2023/09	HEALTH-UNORTE: Setting-up biobanks and regenerative medicine strategies to boost research in cardiovascular, musculoskeletal, neurological, oncological, immunological and infectious diseases NORTE-01-0145-FEDER-000039 Researcher Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Comissao de Coordenacao e Desenvolvimento Regional do Norte Concluded
2019/09 - 2023/09	TRANS-CPA: A transdisciplinary approach to the identification of personalized biomarkers and therapeutic targets for chronic pulmonary aspergillosis LCF/PR/HR17/52190003 Principal investigator Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	"la Caixa" Foundation Fundação para a Ciência e Tecnologia (FCT) Concluded
2021/06 - 2023/06	JUSThera - Janus approach to cancer theranostics NORTE-01-0145-FEDER-000055 Researcher Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Comissao de Coordenacao e Desenvolvimento Regional do Norte Concluded
2021/06 - 2023/06	Dissecting itaconate-mediated mechanisms of antifungal activity in invasive pulmonary aspergillosis Gilead Research Scholars - Anti-Fungals Researcher Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Gilead Sciences Europe Ltd Concluded
2017/01 - 2022/12	The influence of mitogen activated protein kinases (MAPK) on the expression of genetic determinants important for Aspergillus fumigatus virulence 16/07870-9 Researcher Universidade de São Paulo, Brazil	Fundacao de Amparo a Pesquisa do Estado de Sao Paulo Concluded
2019/10 - 2022/09	Immunologic markers for treatment monitoring and diagnosis in invasive mold infection: a multicenter study ISR-NL-18-10601 Principal investigator Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Gilead Sciences Ongoing
2019/09 - 2022/06	The host-fungus interaction in chronic granulomatous disease USP-UMINHO#14 Principal investigator Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Universidade do Minho Universidade de São Paulo Concluded
2018/07 - 2022/05	Innate regulation of inflammation in sarcoidosis PTDC/MED-GEN/28778/2017 Principal investigator Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e Tecnologia (FCT) Concluded
2018/07 - 2022/05	The host-microbiota interaction in fungal diseases: towards biomarker discovery and therapy PTDC/SAU-SER/29635/2017 Co-Principal Investigator (Co-PI) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e Tecnologia (FCT) Concluded
2018/07 - 2021/07	lmmunogenetic determinants of susceptibility/resistance to Buruli ulcer: a family- and population-based study for a neglected tropical disease PTDC/SAU-INF/31312/2017 Researcher Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e Tecnologia (FCT) Concluded
2019/01 - 2020/12	CONNECT: inCreasing cOmmunicatioN, awareNEss and data sharing in a global approaCh against resisTance JPIAMR_2018_N023 Researcher Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Joint Programming Initiative on Antimicrobial Resistance Concluded
2016/03 - 2020/03	Predictive diagnostics and personalized treatment of infectious diseases in patients with hematological malignancies: immunometabolic and genetic control of susceptibility NORTE-45-2015-02 Researcher Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Comissao de Coordenacao e Desenvolvimento Regional do Norte Concluded
2016/02 - 2020/02	The role of inflammasome-autophagy crosstalk in fungal infection IF/00735/2014 Principal investigator Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e Tecnologia (FCT) Concluded
2019/01/01 - 2019/12/31	ICVS/3B¿s - Associate Laboratory, Life and Health Sciences Research Institute / Biomaterials, Biodegradables and Biomimetics Research Group UID/Multi/50026/2019 Universidade do Minho, Portugal Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2017/01 - 2019/12	The genetic architecture of the immune response to Aspergillus fumigatus: from biological understanding to therapeutic intervention ESCMID Research Grant 2017 Principal investigator Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	European Society of Clinical Microbiology and Infectious Diseases Concluded
2017/01 - 2019/12	The genetic architecture of the immune response to Aspergillus fumigatus: from biological understanding to therapeutic intervention Mérieux Research Grant 2017 Researcher Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Institut Merieux Concluded
2017/01 - 2018/12	PTX3-mediated innate regulation of inflammation in sarcoidosis 2CA-Braga Grant 2016 Principal investigator Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Centro Clínico Académico - Braga (2-CA) Concluded
2017/01 - 2018/12	O papel da sobreexpressão de IL-10 na imunidade antifúngica e no risco de infeção fúngica em doentes imunocomprometidos Ações Integradas Luso-Alemãs A-43/16 Principal investigator Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Conselho de Reitores das Universidades Portuguesas (CRUP) Concluded
2016/01 - 2018/12	Translating the host-microbiota interaction into risk assessment of fungal diseases Mérieux Research Grant 2016 Principal investigator Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Institut Merieux Concluded
2016/01 - 2018/12	Transcriptome analysis of animal models of spontaneous healing of Buruli ulcer Infect-ERA/0002/2015 Researcher Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e Tecnologia (FCT) Concluded
2012/04 - 2015/08	Interaction between immune genes and quality of caregiver's behaviours for child's attachment outcomes PTDC/PSI-PCL/116897/2010 Researcher Universidade do Minho Centro de Investigação em Psicologia, Portugal	Fundação para a Ciência e Tecnologia (FCT) Concluded
2012/06 - 2014/05	Genetic variants of PTX3 and invasive aspergillosis: from risk assessment to mechanistic insights ESCMID Research Grant 2012/5 Principal investigator Università degli Studi di Perugia Dipartimento di Medicina Sperimentale, Italy	European Society of Clinical Microbiology and Infectious Diseases Concluded
2012/04 - 2014/05	FunMeta: Metabolomics of fungal diseases: a systems biology approach for biomarkers discovery and therapy ERC-2011-AdG-293714 Researcher Università degli Studi di Perugia Dipartimento di Medicina Sperimentale, Italy	European Research Council Concluded
2012/01 - 2014/05	Targeting pathogenic pathways leading to inflammatory Th17 responses in cystic fibrosis: a drug discovery approach FFC#16/2012 Researcher Università degli Studi di Perugia Dipartimento di Medicina Sperimentale, Italy	Fondazione per la Ricerca sulla Fibrose Cistica Concluded
2010/12 - 2014/05	ALLFUN: Fungi in the setting of inflammation, allergy and autoimmune diseases: translating basic sciences into clinical practices HEALTH-F2-2010-260338 Researcher Università degli Studi di Perugia Dipartimento di Medicina Sperimentale, Italy	European Commission Seventh Framework Programme for Research and Technological Development Concluded
2012/01 - 2013/12	Genetic polymorphisms in patients with invasive aspergillosis: a new frontier for diagnosis and therapy Gilead Fellowship Program 2012 Principal investigator Università degli Studi di Perugia Dipartimento di Medicina Sperimentale, Italy	Gilead Sciences Concluded
2010/01 - 2013/12	The Th17 pathway: new insights into the pathogenesis and treatment of immunoreconstitution diseases through a systems biology approach RF-PGN-2009-1302800 Researcher Università degli Studi di Perugia Dipartimento di Medicina Sperimentale, Italy	Ministero della Salute Concluded
2010/01 - 2011/12	Th17 responses in cystic fibrosis: paving the way for novel anti-inflammatory strategies and immunogenetic screening FFC#21/2010 Researcher Università degli Studi di Perugia Dipartimento di Medicina Sperimentale, Italy	Fondazione per la Ricerca sulla Fibrose Cistica Concluded
2005/06 - 2008/05	A multidisciplinary study of invasive fungal infections in immunosuppressed patients: host susceptibility to fungi versus fungi resistance to drugs POCI/SAU-ESP/61080/2004 Researcher Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e Tecnologia (FCT) Concluded
2003/06 - 2006/05	Cellular and molecular studies in the pathogenic fungi Paracoccidioides brasiliensis: dimorphism and its regulation by steroid hormones POCTI/ESP/45327/2002 Researcher Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundação para a Ciência e Tecnologia (FCT) Concluded
2003/06 - 2006/05	Recognition mechanisms of pathogen-associated molecular patterns: implications in susceptibility to infections relevant to public health Proc/60666-MM/734 Researcher Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal	Fundacao Calouste Gulbenkian Concluded

Outputs

Publications

Book	Carvalho, A.. Immunogenetics of fungal diseases. Springer International Publishing. 2017. 10.1007/978-3-319-50842-9 • Editor
Book chapter	Egger, M.; Carvalho, A.; Goldman, G.H.; Ibrahim, A.S.; Hoenigl, M.. "COVID-19 and secondary fungal infections". In COVID-19 Viral Sepsis: Impact on Disparities, Disabity, and Health Outcomes, edited by Syed, U.; Hou, C., 203-221. Elsevier - Academic Press, 2023. Egger, M.; Carvalho, A.; Goldman, G.H.; Ibrahim, A.S.; Hoenigl, M.. "COVID-19 and secondary fungal infections". 203-221. 2023. Chamilos, G.; Carvalho, A.. "Aspergillus fumigatus DHN-Melanin". In The Fungal Cell Wall, edited by Latgé, J.-P.. Springer International Publishing, 2020. 10.1007/82_2020_205 Gonçalves, S.M.; Duarte-Oliveira, C.; Cunha, C.; Carvalho, A.. "The lung microbiome, metabolome, and breath volatolome in the diagnosis of pulmonary disease". In Microbiome and Metabolome in Diagnosis, Therapy, and other Strategic Applications, edited by Faintuch, J.; Faintuch, S.. Elsevier - Academic Press, 2019. Campos, C.F.; van de Veerdonk, F.L.; Gonçalves, S.M.; Cunha, C.; Netea, M.G.; Carvalho, A.. "Host Genetic Signatures of Susceptibility to Fungal Disease". In Fungal Physiology and Immunopathogenesis, edited by Rodrigues, M.L.. Springer International Publishing, 2019. 10.1007/82_2018_113 Cunha, C.; Gonçalves, S.M.; Carvalho, A.. "Role of deficits in pathogen recognition receptors in infection susceptibility". In Management of Infections in the Immunocompromised Host, edited by Segal, B.H.. Springer International Publishing, 2018. 10.1007/978-3-319-77674-3_6 Rodrigues, C.S.; Campos, C.F.; Cunha, C.; Carvalho, A.. "Metabolic Regulation of Innate Immunity to Fungal Infection". In Metabolic Interaction in Infection, edited by Silvestre, R.; Torrado, E.. Springer International Publishing, 2018. 10.1007/978-3-319-74932-7_11 Cunha, C.; Gonçalves, S.M.; Carvalho, A.. "Host-Derived Biomarkers for Risk Assessment of Invasive Fungal Diseases". In Human Fungal Pathogen Identification, edited by Lion, T.. Springer New York, 2017. 10.1007/978-1-4939-6515-1_7 Carvalho, A.; Cunha, C.; Galosi, C.; Romani, L.. "Antifungal Vaccines and Immunotherapeutics". In Antifungals: From Genomics to Resistance and the Development of Novel Agents, edited by Coste, A.T.; Vandeputte, P.. Caister Academic Press, 2015. 10.21775/9781910190012.12 Cunha, C.; Aversa, F.; Romani, L.; Carvalho, A.. "T cell responses in fungal infections". In Human Fungal Pathogens, edited by Kurzai, O.. Springer Berlin Heidelberg, 2014. 10.1007/978-3-642-39432-4_6
Conference abstract	Feys, S.; Vanmassenhove, S.; Kraisin, S.; Cambier, S.; Jacobs, C.; Boeckx, B.; Van Mol, P.; et al. "Lung hybrid neutrophils and subsequent extracellular traps are protective in COVID-19-associated pulmonary aspergillosis". Paper presented in IDWeek 2022, Washington, DC, 2022. Feys, S.; Gonçalves, S.M.; Khan, M.; Choi, S.; Boeckx, B.; Chatelain, D.; Cunha, C.; et al. "Influenza versus COVID-19-associated pulmonary aspergillosis: Profiling lower respiratory tract epithelial and myeloid innate immunity in patient samples". Paper presented in 21st Congress of the International Society for Human and Animal Mycology, New Delhi, 2022. Dellière, S.; Sze Wah Wong, S.; Chauvin, C.; Bayry, J.; Carvalho, A.; Inforzato, A.; Aimanianda, V.. "Pentraxin-3 interacts with Aspergillus fumigatus conidia to regulate pro-inflammatory cytokine production". Paper presented in 21st Congress of the International Society for Human and Animal Mycology, New Delhi, 2022. Parente, R.; Possetti, V.; Stravalaci, M.; Sironi, M.; Valentino, S.; Day, A.; Bottazzi, B.; et al. "The alternative pathway of complement and long pentraxin PTX3 form a functional axis in the immune response to Aspergillus fumigatus". Paper presented in ICW – 2021 Virtual Workshop of the International Complement Society (ICS), 2021. Wang, X.; Caffrey, A.K.; Espinosa, V.; Cunha, C.; Croteau, W.; Lacerda, J.F.; Campos, A., Jr.; et al. "Mda5/MAVS are essential for host resistance against Aspergillus fumigatus". Paper presented in IMMUNOLOGY2020, Honolulu, 2020. Silva-Gomes, R.; Sironi, M.; Stravalaci, M.; Fontanini, A.; Mattiola, I.; Cunha, C.; Carvalho, A.; et al. "Role of the tetraspan MS4A4A on macrophage-mediated immune responses to pathogens and tumor growth". Paper presented in II Joint Meeting of the German Society for Immunology (DGfl) and the Italian Society of Immunology, Clinical Immunology and Allergology (SIICA), Munich, 2019. Cunha, C.; Goncalves, S. M.; Campos, C. F.; Carvalho, A.. "New insights in diagnosis and immunopathology of aspergillosis". Paper presented in 20th Congress of the International Society for Human and Animal Mycology (ISHAM), Amsterdam, 2018. Stappers, M. H. T.; Clark, A. E.; Aimanianda, V.; Bidula, S.; Reid, D. M.; Asamaphan, P.; Hardison, S. E.; et al. "Recognition of DHN-melanin by the C-type lectin, MelLec, is required for protective immunity to Aspergillus fumigatus". Paper presented in 20th Congress of the International Society for Human and Animal Mycology (ISHAM), Amsterdam, 2018. Dewi, I. M. W.; Cunha, C.; Vanderbeke, L.; Gresnigt, M. S.; Jaeger, M.; Resendiz-Sharpe, A.; Wauters, J.; Carvalho, A.; Van de Veerdonk, F. L.. "The role of oseltamivir in the host response against aspergillosis". Paper presented in 20th Congress of the International Society for Human and Animal Mycology (ISHAM), Amsterdam, 2018. van de Veerdonk, F.L.; Dewi, I.; Cunha, C.; Vanderberke, L.; Jaeger, M.; Gresnigt, M.; Resendiz, A.; et al. "Inhibition of host neuraminidase increases susceptibility to invasive pulmonary aspergillosis". Paper presented in ID Week 2018, San Francisco, 2018. Lupiañez, C.B..; Martínez-Bueno, M.; Sanchez-Maldonado, J.; Cunha, C.; Springer, J.; Lackner, M.; Ríos-Tamayo, R.; et al. "An Immunochip-based approach identifies ARTN2 and CX3CR1 as new risk loci for invasive aspergillosis in high risk hematological patients". Paper presented in The 44th Annual Meeting of the European Society for Blood and Marrow Transplantation, Lisbon, 2018. Goncalves, S. M.; Lagrou, K.; Godzien, J.; Gabaldon, T.; Barbas, C.; Maertens, J. A.; Cunha, C.; Carvalho, A.. "The microbiome-metabolome crosstalk in the pathogenesis of invasive aspergillosis". Paper presented in 8th Trends in Medical Mycology (TIMM), Belgrade, 2017. Silva-Gomes, Rita; Capela, Carlos; Dossou, Ange Dodji; Sopoh, Ghislain Emmanuel; Makoutode, Michel; Menino, Joao Filipe; Fraga, Alexandra Gabriel; et al. "Genetic Variation in Autophagy-Related Genes Influences the Risk and Phenotype of Buruli Ulcer". Paper presented in XI National Congress of the Italian Society of Immunology, Clinical Immunology and Allergology (SIICA), Bari, 2017. Lima, Ana Cláudia; Cunha, Cristina; Carvalho, Agostinho; Ferreira, Helena; Neves, Nuno M.. "Advanced treatment for arthritic diseases based on the capture and inactivation of interleukin-6 by biofunctionalized polymeric nanoparticles". Paper presented in European Chapter Meeting of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-EU) 2017, Davos, 2017. Carvalho, A.. "PTX3-based genetic testing for risk of aspergillosis". Paper presented in Myk2015, Jena, 2015. Carvalho, A.. "Complex host genetic susceptibility to fungal infection". Paper presented in 7th Trends in Medical Mycology (TIMM), Lisbon, 2015. Sainz, J.; Lupianez, C. B.; Canet, L.; Alcazar-Fuoli, L.; Carvalho, A.; Springer, J.; Lackner, M.; et al. "POLYMORPHISMS IN IMMUNOMODULATING GENES AND RISK OF INVASIVE ASPERGILLOSIS: RESULTS FROM THE ASPBIOMICS CONSORTIUM". Paper presented in 20th Congress of the European Hematology Association (EHA), Vienna, 2015. De Luca, A.; Iannitti, R. G.; Giovannini, G.; Carvalho, A.; Cunha, C.; Romani, L.. "Compartimentalization of CD4/CD8 T cell-targeted vaccination in aspergillosis: The molecular basis of personalized vaccines". Paper presented in 18th Congress of the International Society for Human and Animal Mycology (ISHAM), Berlin, 2012. Iannitti, R. G.; Carvalho, A.; De Luca, A.; Giovannini, G.; Casagrande, A.; Cunha, C.; De Benedictis, F. M.; Romani, L.. "CYSTIC FIBROSIS TH17/TREG IMBALANCE TO ASPERGILLUS FUMIGATUS: INSIGHTS FOR NOVEL ANTI-INFLAMMATORY STRATEGIES AND IMMUNOGENETIC SCREENING". Paper presented in 26th Annual North American Cystic Fibrosis Conference, Orlando, 2012. Carvalho, A.; Cunha, C.; Martire, B.; De Mattia, D.; Pignata, C.; Soresina, A.; Plebani, A.; et al. "THE IMPACT OF GENETIC VARIANTS IN THE TH17 INFLAMMATORY PATHWAY TO THE SUSCEPTIBILITY TO INFECTIONS IN PATIENTS WITH CHRONIC GRANULOMATOUS DISEASE". Paper presented in 15th Biennial Meeting of the European Society for Immunodeficiencies, Florence, 2012. Almeida, A. J.; Cunha, C.; Marques, B.; Carmona, J. A.; Carvalho, A.; Logarinho, E.; Leao, C.; et al. "Singular yeast cell morphology of Paracoccidioides brasiliensis is associated to virulence: down-regulation of the CDC42 homolog". Paper presented in 33rd FEBS Congress & 11th IUBMB Conference, Athens, 2008.
Journal article	Samuel M. Gonçalves; Inês Pereira; Simon Feys; Cristina Cunha; Georgios Chamilos; Martin Hoenigl; Joost Wauters; Frank L. van de Veerdonk; Carvalho, Agostinho. "Integrating genetic and immune factors to uncover pathogenetic mechanisms of viral-associated pulmonary aspergillosis". mBio (2024): 10.1128/mbio.01982-23 Martin Hoenigl; Amir Arastehfar; Maiken Cavling Arendrup; Roger Brüggemann; Agostinho Carvalho; Tom Chiller; Sharon Chen; et al. "Novel antifungals and treatment approaches to tackle resistance and improve outcomes of invasive fungal disease". Clinical Microbiology Reviews (2024): e0007423. 10.1128/cmr.00074-23 Rita Silva-Gomes; Inês Caldeira; Raquel Fernandes; Cristina Cunha; Agostinho Carvalho. "Metabolic regulation of the host–fungus interaction: from biological principles to therapeutic opportunities". Journal of Leukocyte Biology (2024): 10.1093/jleuko/qiae045 Fernandes, R.; Sabino, R.; Cunha, C.; Cornely, O.A.; Carvalho, Agostinho; Salmanton-García, J.. "Multicentric Study on the Clinical Mycology Capacity and Access to Antifungal Treatment in Portugal". Mycopathologia 189 1 (2024): 15. 10.1007/s11046-024-00830-9 Feys, S.; Vanmassenhove, S.; Kraisin, S.; Yu, K.; Jacobs, C.; Boeckx, B.; Cambier, S.; et al. "Lower respiratory tract single-cell RNA sequencing and neutrophil extracellular trap profiling of COVID-19-associated pulmonary aspergillosis: a single centre, retrospective, observational study". The Lancet Microbe 5 3 (2024): e247-e260. 10.1016/S2666-5247(23)00368-3 Aerts, R.; Ricaño-Ponce, I.; Bruno, M.; Mercier, T.; Rosati, D.; Maertens, J.; Kumar, V.; et al. "Circulatory Inflammatory Proteins as Early Diagnostic Biomarkers for Invasive Aspergillosis in Patients with Hematologic Malignancies—an Exploratory Study". Mycopathologia 189 2 (2024): 24. 10.1007/s11046-024-00831-8 Valentino, R.R.; Scotton, W.J.; Roemer, S.F.; Lashley, T.; Heckman, M.G.; Shoai, M.; Martinez-Carrasco, A.; et al. "MAPT H2 haplotype and risk of Pick's disease in the Pick's disease International Consortium: a genetic association study". The Lancet Neurology 23 5 (2024): 487-499. 10.1016/S1474-4422(24)00083-8 Matheus Tavares; Jorge Carlos Sousa-Filho; Ian Alves Machado; Relber Aguiar Gonçales; Daniela Antunes; Ana Mendes-Frias; Ricardo Silvestre; et al. "Development of a Versatile Toolbox for Genetic Manipulation of Sporothrix brasiliensis". Microbiology Spectrum 11 2 (2023): e0456422. 10.1128/spectrum.04564-22 Vieira, S.F.; Gonçalves, S.M.; Gonçalves, V.M.F.; Llaguno, C.P.; Macías, F.; Tiritan, M.E.; Cunha, C.; et al. "Echinacea purpurea Fractions Represent Promising Plant-Based Anti-Inflammatory Formulations". Antioxidants 12 2 (2023): 425. 10.3390/antiox12020425 Antunes, D.; Gonçalves, S.M.; Matzaraki, V.; Rodrigues, C.S.; Gonçales, R.A.; Rocha, J.; Sáiz, J.; et al. "Glutamine Metabolism Supports the Functional Activity of Immune Cells against Aspergillus fumigatus". Microbiology Spectrum 11 1 (2023): e0225622. 10.1128/spectrum.02256-22 Feys, S.; Heylen, J.; Carvalho, A.; Van Weyenbergh, J.; Wauters, J.; Gonçalves, S.M.; Cunha, C.; et al. "A signature of differential gene expression in bronchoalveolar lavage fluid predicts mortality in influenza-associated pulmonary aspergillosis". Intensive Care Medicine 49 2 (2023): 254-257. 10.1007/s00134-022-06958-w Jia, L.-J.; Rafiq, M.; Radosa, L.; Hortschansky, P.; Cunha, C.; Cseresnyés, Z.; Krüger, T.; et al. "Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway". Cell Host & Microbe 31 3 (2023): 373-388. 10.1016/j.chom.2023.02.002 Araújo, M.; Moreira, D.; Mesquita, I.; Ferreira, C.; Mendes-Frias, A.; Barros-Carvalho, S.; Dinis-Oliveira, R.J.; et al. "Intramacrophage lipid accumulation compromises T cell responses and is associated with impaired drug therapy against visceral leishmaniasis". Immunology 170 4 (2023): 510-526. 10.1111/imm.13686 Hyde, K.D.; Abdel-Wahab, M.A.; Abdollahzadeh, J.; Abeywickrama, P.D.; Absalan, S.; Afshari, N.; Ainsworth, A.M.; et al. "Global consortium for the classification of fungi and fungus-like taxa". Mycosphere 14 1 (2023): 1960-2012. 10.5943/mycosphere/14/1/23 Hoenigl, M.; Seidel, D.; Sprute, R.; Cunha, C.; Oliverio, M.; Goldman, G.H.; Ibrahim, A.S.; Carvalho, A.. "COVID-19-associated fungal infections". Nature Microbiology 7 8 (2022): 1127-1140. 10.1038/s41564-022-01172-2 Feys, S.; Gonçalves, S.M.; Khan, M.; Choi, S.; Boeckx, B.; Chatelain, D.; Cunha, C.; et al. "Lung epithelial and myeloid innate immunity in influenza-associated or COVID-19-associated pulmonary aspergillosis: an observational study". The Lancet Respiratory Medicine 10 12 (2022): 1147-1159. 10.1016/S2213-2600(22)00259-4 Ferreira, C.M.; Micheli, C.; Barreira-Silva, P.; Barbosa, A.M.; Resende, M.; Vilanova, M.; Silvestre, R.; et al. "IL-10 Overexpression After BCG Vaccination Does Not Impair Control of Mycobacterium tuberculosis Infection". Frontiers in Immunology 13 (2022): 946181. 10.3389/fimmu.2022.946181 Wang, X.; Cunha, C.; Grau, M.S.; Robertson, S.J.; Lacerda, J.F.; Campos, A., Jr.; Lagrou, K.; et al. "MAVS Expression in Alveolar Macrophages Is Essential for Host Resistance against Aspergillus fumigatus". The Journal of Immunology 209 2 (2022): 346-353. 10.4049/jimmunol.2100759 Gonçales, R.A.; Bastos, H.N.; Duarte-Oliveira, C.; Antunes, D.; Sokhatska, O.; Jacob, M.; Rolo, R.; et al. "Pentraxin 3 Inhibits Complement-driven Macrophage Activation to Restrain Granuloma Formation in Sarcoidosis". American Journal of Respiratory and Critical Care Medicine 206 9 (2022): 1140-1152. 10.1164/rccm.202112-2771OC Egger, M.; Hoenigl, M.; Thompson, G.R. 3rd; Carvalho, A.; Jenks, J.D.. "Let's talk about sex characteristics: As a risk factor for invasive fungal diseases". Mycoses 65 6 (2022): 599-612. 10.1111/myc.13449 Olival, A.; Vieira, S.F.; Gonçalves, V.M.F.; Cunha, C.; Tiritan, M.E.; Carvalho, A.; Reis, R.L.; Ferreira, H.; Neves, N.M.. "Erythrocyte-derived liposomes for the treatment of inflammatory diseases". Journal of Drug Targeting (2022): 1-11. 10.1080/1061186X.2022.2066107 Hoenigl, M.; Seidel, D.; Carvalho, A.; Rudramurthy, S.M.; Arastehfar, A.; Gangneux, J.P.; Nasir, N.; et al. "The emergence of COVID-19 associated mucormycosis: a review of cases from 18 countries". The Lancet Microbe 3 7 (2022): e543-e552. 10.1016/s2666-5247(21)00237-8 Hérivaux, A.; Willis, J.R.; Mercier, T.; Lagrou, K.; Gonçalves, S.M.; Gonçales, R.A.; Maertens, J.; et al. "Lung microbiota predict invasive pulmonary aspergillosis and its outcome in immunocompromised patients". Thorax 77 3 (2022): 283-291. 10.1136/thoraxjnl-2020-216179 de Castro, P.A.; Colabardini, A.C.; Moraes, M.; Horta, M.A.C.; Knowles, S.L.; Raja, H.A.; Oberlies, N.H.; et al. 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"Hypoxia inducible-factor 1 alpha regulates neutrophil recruitment during fungal-elicited granulomatous inflammation". Frontiers in Cellular and Infection Microbiology 12 (2022): 1005839. 10.3389/fcimb.2022.1005839 Ferreira, C.M.; Barbosa, A.M.; Barreira-Silva, P.; Silvestre, R.; Cunha, C.; Carvalho, A.; Rodrigues, F.; et al. "Early IL-10 promotes vasculature-associated CD4+ T cells unable to control Mycobacterium tuberculosis infection". JCI Insight 6 21 (2021): e150060. 10.1172/jci.insight.150060 Castro, I.; Sampaio-Marques, B.; Areias, A.C.; Sousa, H.; Fernandes, Â.; Sánchez-Maldonado, J.M.; Cunha, C.; et al. "Functional Genetic Variants in ATG10 Are Associated with Acute Myeloid Leukemia". Cancers 13 6 (2021): 1344-1344. 10.3390/cancers13061344 Bruno, M.; Dewi, I.M.W.; Matzaraki, V.; ter Horst, R.; Pekmezovic, M.; Rösler, B.; Groh, L.; et al. 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Frontiers in Microbiology 12 12 (2021): 655069. 10.3389/fmicb.2021.655069 Dewi, I.M.W.; Cunha, C.; Jaeger, M.; Gresnigt, M.S.; Gkountzinopoulou, M.E.; Garishah, F.M.; Duarte-Oliveira, C.; et al. "Neuraminidase and SIGLEC15 modulate the host defense against pulmonary aspergillosis". Cell Reports Medicine 2 5 (2021): 100289. 10.1016/j.xcrm.2021.100289 Sueiro-Olivares, M.; Scott, J.; Gago, S.; Petrovic, D.; Kouroussis, E.; Zivanovic, J.; Yu, Y.; et al. "Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response". PLoS Biology 19 6 (2021): e3001247. 10.1371/journal.pbio.3001247 Doni, A.; Parente, R.; Laface, I.; Magrini, E.; Cunha, C.; Colombo, F.S.; Lacerda, J.F.; et al. "Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus". Nature Communications 12 1 (2021): 3739. 10.1038/s41467-021-24021-y Gonçalves, S.M.; Antunes, D.; Leite, L.; Mercier, T.; Horst, R.T.; Vieira, J.; Espada, E.; et al. "Genetic variation in PFKFB3 impairs antifungal immunometabolic responses and predisposes to invasive pulmonary aspergillosis". mBio 12 3 (2021): e0036921. 10.1128/mBio.00369-21 Gonçales, R.A.; Ricci-Azevedo, R.; Vieira, V.C.S.; Fernandes, F.F.; Thomaz, S.M.D.O.; Carvalho, A.; Vendruscolo, P.E.; et al. "Paracoccin Overexpression in Paracoccidioides brasiliensis Enhances Fungal Virulence by Remodeling Chitin Properties of the Cell Wall". Journal of Infectious Diseases 224 1 (2021): 164-174. 10.1093/infdis/jiaa707 Reis, J.; van de Veerdonk, F.L.; Carvalho, A.; Fernandes, A.; Machado, S.. "The potential role for topical imiquimod in the treatment of chronic mucocutaneous candidiasis caused by gain-of-function mutation in STAT1: A case-report". Dermatologic Therapy (2021): e15043. 10.1111/dth.15043 Ries, L.N.A.; Alves de Castro, P.; Pereira Silva, L.; Valero, C.; Dos Reis, T.F.; Saborano, R.; Duarte, I.F.; et al. "Aspergillus fumigatus Acetate Utilization Impacts Virulence Traits and Pathogenicity". mBio 12 4 (2021): e0168221-e0168221. 10.1128/mBio.01682-21 Machata, S.; Müller, M.M.; Lehmann, R.; Sieber, P.; Panagiotou, G.; Carvalho, A.; Cunha, C.; et al. "Proteome analysis of bronchoalveolar lavage fluids reveals host and fungal proteins highly expressed during invasive pulmonary aspergillosis in mice and humans". Virulence 11 1 (2020): 1337-1351. 10.1080/21505594.2020.1824960 Lima, A.C.; Campos, C.F.; Cunha, C.; Carvalho, A.; Reis, R.L.; Ferreira, H.; Neves, N.M.. "Biofunctionalized Liposomes to Monitor Rheumatoid Arthritis Regression Stimulated by Interleukin-23 Neutralization". Advanced Healthcare Materials (2020): e2001570. 10.1002/adhm.202001570 Arastehfar, A.; Carvalho, A.; Nguyen, M.H.; Hedayati, M.T.; Netea, M.G.; Perlin, D.S.; Hoenigl, M.. "COVID-19-Associated Candidiasis (CAC): An Underestimated Complication in the Absence of Immunological Predispositions?". Journal of Fungi 6 4 (2020): 211. 10.3390/jof6040211 Mondanelli, G.; Carvalho, A.; Puccetti, P.; Grohmann, U.; Volpi, C.. "Reply to Han et al.: On track for an IDO1-based personalized therapy in autoimmunity". Proceedings of the National Academy of Sciences 117 39 (2020): 24037-24038. 10.1073/pnas.2016277117 Arastehfar, A.; Carvalho, A.; Van De Veerdonk, F.L.; Jenks, J.D.; Philipp Koehler; Krause, R.; Cornely, O.A.; et al. "COVID-19 Associated Pulmonary Aspergillosis (CAPA): From Immunology to Treatment". Journal of Fungi 6 2 (2020): e91. 10.3390/jof6020091 Obar, J.J.; Carvalho, A.; Vitte, J.; Ranque, S.. "Editorial: Host and Pathogen Determinants of Allergic and Invasive Fungal Diseases". Frontiers in Immunology 11 (2020): 856. 10.3389/fimmu.2020.00856 Mesquita, I.; Ferreira, C.; Moreira, D.; Kluck, G.E.G.; Barbosa, A.M.; Torrado, E.; Dinis-Oliveira, R.J.; et al. "The Absence of HIF-1a Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis". Cell Reports 30 12 (2020): 4052-4064.e7. 10.1016/j.celrep.2020.02.098 Pinto, R.; Belsky, J.; Baptista, J.; Carvalho, A.; Cunha, C.; Soares, I.; Mesquita, A.R.. "Mothers' distress exposure and children's withdrawn behavior: A moderating role for the Interferon Gamma gene (IFNG)". Developmental Psychobiology 62 6 (2020): 783-791. 10.1002/dev.21955 Lupiañez, C.B.; Martínez-Bueno, M.; Sánchez-Maldonado, J.M.; Badiola, J.; Cunha, C.; Springer, J.; Lackner, M.; et al. "Polymorphisms within the ARNT2 and CX3CR1 Genes Are Associated with the Risk of Developing Invasive Aspergillosis". Infection and Immunity 88 4 (2020): e0088219. 10.1128/IAI.00882-19 Mondanelli, G.; Coletti, A.; Greco, F.A.; Pallotta, M.T.; Orabona, C.; Iacono, A.; Belladonna, M.L.; et al. "Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation". Proceedings of the National Academy of Sciences of the United States of America 117 7 (2020): 3848-3857. 10.1073/pnas.1918215117 Ferreira, C.; Mesquita, I.; Barbosa, A.M.; Osório, N.S.; Torrado, E.; Beauparlant, C.-J.; Droit, A.; et al. "Glutamine supplementation improves the efficacy of miltefosine treatment for visceral leishmaniasis". PLoS Neglected Tropical Diseases 14 3 (2020): e0008125. 10.1371/journal.pntd.0008125 Gonçalves, S.M.; Duarte-Oliveira, C.; Campos, C.F.; Aimanianda, V.; Ter Horst, R.; Leite, L.; Mercier, T.; et al. "Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity". Nature Communications 11 1 (2020): 2282. 10.1038/s41467-020-16120-z Sánchez-Maldonado, J.M.; Campa, D.; Springer, J.; Badiola, J.; Niazi, Y.; Moñiz-Díez, A.; Hernández-Mohedo, F.; et al. "Host immune genetic variations influence the risk of developing acute myeloid leukaemia: results from the NuCLEAR consortium". Blood Cancer Journal 10 7 (2020): 75. 10.1038/s41408-020-00341-y Alves, N.L.; Carvalho, A.; Serre, K.; Martins, V.C.; Saraiva, M.. "The Portuguese Society for Immunology (SPI): history and mission". European Journal of Immunology 50 7 (2020): 918-920. 10.1002/eji.202070075 Hérivaux, A.; Gonçalves, S.M.; Carvalho, A.; Cunha, C.. "Microbiota-derived metabolites as diagnostic markers for respiratory fungal infections". Journal of Pharmaceutical and Biomedical Analysis 189 (2020): 113473. 10.1016/j.jpba.2020.113473 Schmidt, F.; Thywißen, A.; Goldmann, M.; Cunha, C.; Cseresnyés, Z.; Schmidt, H.; Rafiq, M.; et al. "Flotillin-Dependent Membrane Microdomains Are Required for Functional Phagolysosomes against Fungal Infections". Cell Reports 32 7 (2020): 108017. 10.1016/j.celrep.2020.108017 Chamilos, G.; Carvalho, A.. "Aspergillus fumigatus DHN-Melanin". Current Topics in Microbiology and Immunology 425 (2020): 17-28. 10.1007/82_2020_205 Carvalho, A.; van de Veerdonk, F.L.. "Editorial overview: Emerging topics in host-fungus interactions". Current Opinion in Microbiology 58 (2020): iii-v. 10.1016/j.mib.2020.11.007 Campos, C.F.; Leite, L.; Pereira, P.; Vaz, C.P.; Branca, R.; Campilho, F.; Freitas, F.; et al. "PTX3 Polymorphisms Influence Cytomegalovirus Reactivation After Stem-Cell Transplantation". Frontiers in Immunology 10 (2019): 88. 10.3389/fimmu.2019.00088 Ferreira, B.H.; Ramírez-Prado, J.H.; Neves, G.W.P.; Torrado, E.; Sampaio, P.; Felipe, M.S.S.; Vasconcelos, A.T.; et al. "Ploidy determination in the pathogenic fungus Sporothrix spp". Frontiers in Microbiology 10 FEB (2019): 284. 10.3389/fmicb.2019.00284 Antunes, D.; Cunha, C.; Carvalho, A.. "Genetic Regulation of the Host-Fungus Interaction in the Pathogenesis of Aspergillosis". Current Fungal Infection Reports 13 3 (2019): 77-85. 10.1007/s12281-019-00344-8 Bernal-Martínez, L.; Alcazar Fuoli, L.; Miguel-Revilla, B.; Carvalho, A.; Cuétara Garcia, M.S.; Garcia-Rodriguez, J.; Cunha, C.; Gómez-García de la Pedrosa, E.; Gomez-Lopez, A.. "High-resolution melting assay for genotyping variants of the CYP2C19 enzyme and predicting voriconazole effectiveness". Antimicrobial Agents and Chemotherapy 63 6 (2019): e02399-18. 10.1128/AAC.02399-1 Jenks, J.D.; Rawlings, S.A.; Garcia-Vidal, C.; Koehler, P.; Mercier, T.; Prattes, J.; Lass-Flörl, C.; et al. "Immune parameters for diagnosis and treatment monitoring in invasive mold infection". Journal of Fungi 5 4 (2019): 116. 10.3390/jof5040116 Bacelo, E.; Da Silva, M.A.; Cunha, C.; Faria, S.; Carvalho, A.; Reis, R.L.; Martins, A.; Neves, N.M.. "Biofunctional nanofibrous substrate for local TNF-capturing as a strategy to control inflammation in arthritic joints". Nanomaterials 9 4 (2019): 10.3390/nano9040567 Cunha, C.; Carvalho, A.. "Genetic defects in fungal recognition and susceptibility to invasive pulmonary aspergillosis". Medical Mycology 57 (2019): S211-S218. 10.1093/mmy/myy057 Mondanelli, G.; Iacono, A.; Carvalho, A.; Orabona, C.; Volpi, C.; Pallotta, M.T.; Matino, D.; Esposito, S.; Grohmann, U.. "Amino acid metabolism as drug target in autoimmune diseases". Autoimmunity Reviews 18 4 (2019): 334-348. 10.1016/j.autrev.2019.02.004 Campos, C.F.; van de Veerdonk, F.L.; Gonçalves, S.M.; Cunha, C.; Netea, M.G.; Carvalho, A.. "Host Genetic Signatures of Susceptibility to Fungal Disease". Current Topics in Microbiology and Immunology 422 (2019): 237-263. 10.1007/82_2018_113 Stappers, M.H.T.; Clark, A.E.; Aimanianda, V.; Bidula, S.; Reid, D.M.; Asamaphan, P.; Hardison, S.E.; et al. "Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus". Nature 555 7696 (2018): 382-386. 10.1038/nature25974 Gresnigt, M.S.; Cunha, C.; Jaeger, M.; Gonçalves, S.M.; Malireddi, R.K.S.; Ammerdorffer, A.; Lubbers, R.; et al. "Genetic deficiency of NOD2 confers resistance to invasive aspergillosis". Nature Communications 9 1 (2018): 2636. 10.1038/s41467-018-04912-3 Chaouali, M.; Carvalho, A.; Tezeghdenti, A.; Ben Azaiez, M.; Cunha, C.; Ghazouani, E.; Kochkar, R.. "Cytotoxic T lymphocyte antigen-4 gene polymorphisms and susceptibility to type 1 autoimmune hepatitis in the Tunisian population". Genes and Diseases 5 3 (2018): 256-262. 10.1016/j.gendis.2017.12.006 Mesquita, I.; Ferreira, C.; Barbosa, A.M.; Ferreira, C.M.; Moreira, D.; Carvalho, A.; Cunha, C.; et al. "The impact of IL-10 dynamic modulation on host immune response against visceral leishmaniasis". Cytokine 112 (2018): 16-20. 10.1016/j.cyto.2018.07.001 Gaifem, J.; Gonçalves, L.G.; Dinis-Oliveira, R.J.; Cunha, C.; Carvalho, A.; Torrado, E.; Rodrigues, F.; et al. "L-threonine supplementation during colitis onset delays disease recovery". Frontiers in Physiology 9 SEP (2018): 1247. 10.3389/fphys.2018.01247 Kyrmizi, I.; Ferreira, H.; Carvalho, A.; Figueroa, J.A.L.; Zarmpas, P.; Cunha, C.; Akoumianaki, T.; et al. "Calcium sequestration by fungal melanin inhibits calcium-calmodulin signalling to prevent LC3-associated phagocytosis". Nature Microbiology 3 7 (2018): 791-803. 10.1038/s41564-018-0167-x Cunha, C.; Carvalho, A.. "Toward the Identification of a Genetic Risk Signature for Pulmonary Aspergillosis in Chronic Obstructive Pulmonary Disease". Clinical Infectious Diseases 66 7 (2018): 1153-1154. 10.1093/cid/cix944 Lima, A.C.; Cunha, C.; Carvalho, A.; Ferreira, H.; Neves, N.M.. "Interleukin-6 Neutralization by Antibodies Immobilized at the Surface of Polymeric Nanoparticles as a Therapeutic Strategy for Arthritic Diseases". ACS Applied Materials and Interfaces 10 16 (2018): 13839-13850. 10.1021/acsami.8b01432 Rodrigues, C.S.; Campos, C.F.; Cunha, C.; Carvalho, A.. "Metabolic Regulation of Innate Immunity to Fungal Infection". Experientia Supplementum 109 (2018): 403-420. 10.1007/978-3-319-74932-7_11 Cunha, C.; Carvalho, A.. "Host Genetics Takes a Toll on Immunity to Cryptococcus". EBioMedicine 37 (2018): 9-10. 10.1016/j.ebiom.2018.10.064 Orabona, C.; Mondanelli, G.; Pallotta, M.T.; Carvalho, A.; Albini, E.; Fallarino, F.; Vacca, C.; et al. "Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1 in juvenile diabetes". JCI insight 3 6 (2018): 10.1172/jci.insight.96244 Gresnigt, M.S.; Jaeger, M.; Subbarao Malireddi, R.K.; Rasid, O.; Jouvion, G.; Fitting, C.; Melchers, W.J.; et al. "The absence of NOD1 enhances killing of Aspergillus fumigatus through modulation of dectin-1 expression". Frontiers in Immunology 8 DEC (2017): 1777. 10.3389/fimmu.2017.01777 Cunha, C.; Gonçalves, S.M.; Duarte-Oliveira, C.; Leite, L.; Lagrou, K.; Marques, A.; Lupiañez, C.B.; et al. "IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity". Journal of Allergy and Clinical Immunology 140 3 (2017): 867-870.e9. 10.1016/j.jaci.2017.02.034 Gonçalves, S.M.; Lagrou, K.; Rodrigues, C.S.; Campos, C.F.; Bernal-Martínez, L.; Rodrigues, F.; Silvestre, R.; et al. "Evaluation of bronchoalveolar lavage fluid cytokines as biomarkers for invasive pulmonary aspergillosis in at-risk patients". Frontiers in Microbiology 8 NOV (2017): 2362. 10.3389/fmicb.2017.02362 Duarte-Oliveira, C.; Rodrigues, F.; Gonçalves, S.M.; Goldman, G.H.; Carvalho, A.; Cunha, C.. "The cell biology of the Trichosporon-host interaction". Frontiers in Cellular and Infection Microbiology 7 APR (2017): 118. 10.3389/fcimb.2017.00118 Carvalho, A.; Duarte-Oliveira, C.; Gonçalves, S.M.; Campos, A.; Lacerda, J.F.; Cunha, C.. "Fungal Vaccines and Immunotherapeutics: Current Concepts and Future Challenges". Current Fungal Infection Reports 11 1 (2017): 16-24. 10.1007/s12281-017-0272-y Carvalho, A.; Goldman, G.H.. "Editorial: An omics perspective on fungal infection: Toward next-generation diagnosis and therapy". Frontiers in Microbiology 8 JAN (2017): 85. 10.3389/fmicb.2017.00085 Fernandes, F.F.; Oliveira, A.F.; Landgraf, T.N.; Cunha, C.; Carvalho, A.; Vendruscolo, P.E.; Gonçales, R.A.; et al. "Impact of paracoccin gene silencing on Paracoccidioides brasiliensis Virulence". mBio 8 4 (2017): e00537. 10.1128/mBio.00537-17 Gonçalves, S.M.; Lagrou, K.; Duarte-Oliveira, C.; Maertens, J.A.; Cunha, C.; Carvalho, A.. "The microbiome-metabolome crosstalk in the pathogenesis of respiratory fungal diseases". Virulence 8 6 (2017): 673-684. 10.1080/21505594.2016.1257458 Cunha, C.; Gonçalves, S.M.; Carvalho, A.. "Host-Derived Biomarkers for Risk Assessment of Invasive Fungal Diseases.". Methods in Molecular Biology 1508 (2017): 153-165. 10.1007/978-1-4939-6515-1_7 Chorny, A.; Casas-Recasens, S.; Sintes, J.; Shan, M.; Polentarutti, N.; García-Escudero, R.; Walland, A.C.; et al. "The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells". Journal of Experimental Medicine 213 10 (2016): 2167-2185. 10.1084/jem.20150282 Arts, R.J.W.; Carvalho, A.; La Rocca, C.; Palma, C.; Rodrigues, F.; Silvestre, R.; Kleinnijenhuis, J.; et al. "Immunometabolic Pathways in BCG-Induced Trained Immunity". Cell Reports 17 10 (2016): 2562-2571. 10.1016/j.celrep.2016.11.011 Arts, R.J.W.; Novakovic, B.; ter Horst, R.; Carvalho, A.; Bekkering, S.; Lachmandas, E.; Rodrigues, F.; et al. "Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity". Cell Metabolism 24 6 (2016): 807-819. 10.1016/j.cmet.2016.10.008 Lupiañez, C.B.; Canet, L.M.; Carvalho, A.; Alcazar-Fuoli, L.; Springer, J.; Lackner, M.; Segura-Catena, J.; et al. "Polymorphisms in host immunity-modulating genes and risk of invasive aspergillosis: Results from the AspBIOmics Consortium". Infection and Immunity 84 3 (2016): 643-657. 10.1128/IAI.01359-15 Jaeger, M.; Carvalho, A.; Cunha, C.; Plantinga, T. S.; van de Veerdonk, F.; Puccetti, M.; Galosi, C.; et al. "Association of a variable number tandem repeat in the NLRP3 gene in women with susceptibility to RVVC". European Journal of Clinical Microbiology & Infectious Diseases 35 5 (2016): 797-801. 10.1007/s10096-016-2600-5 Capela, C.; Dossou, A.D.; Silva-Gomes, R.; Sopoh, G.E.; Makoutode, M.; Menino, J.F.; Fraga, A.G.; et al. "Genetic Variation in Autophagy-Related Genes Influences the Risk and Phenotype of Buruli Ulcer". PLoS Neglected Tropical Diseases 10 4 (2016): e0004671. 10.1371/journal.pntd.0004671 Lupiañez, C.B.; Villaescusa, M.T.; Carvalho, A.; Springer, J.; Lackner, M.; Sánchez-Maldonado, J.M.; Canet, L.M.; et al. "Common genetic polymorphisms within NF¿B-related genes and the risk of developing invasive aspergillosis". Frontiers in Microbiology 7 AUG (2016): 1243. 10.3389/fmicb.2016.01243 Oliveira-Coelho, A.; Rodrigues, F.; Campos, A.; Lacerda, J.F.; Carvalho, A.; Cunha, C.. "Paving the way for predictive diagnostics and personalized treatment of invasive aspergillosis". Frontiers in Microbiology 6 MAY (2015): 411. 10.3389/fmicb.2015.00411 Cunha, C.; Monteiro, A.A.; Oliveira-Coelho, A.; Kühne, J.; Rodrigues, F.; Sasaki, S.D.; Schio, S.M.; et al. "PTX3-Based Genetic Testing for Risk of Aspergillosis after Lung Transplant". Clinical Infectious Diseases 61 12 (2015): 1893-1894. 10.1093/cid/civ679 Bozza, S.; Campo, S.; Arseni, B.; Inforzato, A.; Ragnar, L.; Bottazzi, B.; Mantovani, A.; et al. "PTX3 binds MD-2 and promotes TRIF-dependent immune protection in aspergillosis". Journal of Immunology 193 5 (2014): 2340-2348. 10.4049/jimmunol.1400814 Cunha, C.; Kurzai, O.; Löffler, J.; Aversa, F.; Romani, L.; Carvalho, A.. "Neutrophil Responses to Aspergillosis: New Roles for Old Players". Mycopathologia 178 5-6 (2014): 387-393. 10.1007/s11046-014-9796-7 Cunha, C.; Aversa, F.; Lacerda, J.F.; Busca, A.; Kurzai, O.; Grube, M.; Löffler, J.; et al. "Genetic PTX3 deficiency and aspergillosis in stem-cell transplantation". New England Journal of Medicine 370 5 (2014): 421-432. 10.1056/NEJMoa1211161 Cunha, C.; Kurzai, O.; Carvalho, A.. "PTX3 Deficiency and Aspergillosis". New England Journal of Medicine 370 17 (2014): 1666-1667. 10.1056/NEJMc1402787 Cunha, C.; Aversa, F.; Romani, L.; Carvalho, A.. "Human Genetic Susceptibility to Invasive Aspergillosis". PLoS Pathogens 9 8 (2013): e1003434. 10.1371/journal.ppat.1003434 Potenza, L.; Vallerini, D.; Barozzi, P.; Riva, G.; Forghieri, F.; Beauvais, A.; Beau, R.; et al. "Characterization of Specific Immune Responses to Different Aspergillus Antigens during the Course of Invasive Aspergillosis in Hematologic Patients". PLoS ONE 8 9 (2013): e74326. 10.1371/journal.pone.0074326 De Luca, A.; Carvalho, A.; Cunha, C.; Iannitti, R.G.; Pitzurra, L.; Giovannini, G.; Mencacci, A.; et al. "IL-22 and IDO1 Affect Immunity and Tolerance to Murine and Human Vaginal Candidiasis". PLoS Pathogens 9 7 (2013): e1003486. 10.1371/journal.ppat.1003486 Iannitti, R.G.; Casagrande, A.; De Luca, A.; Cunha, C.; Sorci, G.; Riuzzi, F.; Borghi, M.; et al. "Hypoxia promotes danger-mediated inflammation via receptor for advanced glycation end products in cystic fibrosis". American Journal of Respiratory and Critical Care Medicine 188 11 (2013): 1338-1350. 10.1164/rccm.201305-0986OC Menino, J.F.; Saraiva, M.; Gomes-Alves, A.G.; Lobo-Silva, D.; Sturme, M.; Gomes-Rezende, J.; Saraiva, A.L.; et al. "TLR9 Activation Dampens the Early Inflammatory Response to Paracoccidioides brasiliensis, Impacting Host Survival". PLoS Neglected Tropical Diseases 7 7 (2013): e2317. 10.1371/journal.pntd.0002317 Iannitti, R.G.; Carvalho, A.; Cunha, C.; De Luca, A.; Giovannini, G.; Casagrande, A.; Zelante, T.; et al. "Th17/Treg imbalance in murine cystic fibrosis is linked to indoleamine 2,3-dioxygenase deficiency but corrected by kynurenines". American Journal of Respiratory and Critical Care Medicine 187 6 (2013): 609-620. 10.1164/rccm.201207-1346OC Zelante, T.; Iannitti, R.; Cunha, C.; DeLuca, A.; Giovannini, G.; Pieraccini, G.; Zecchi, R.; et al. "Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22". Immunity 39 2 (2013): 372-385. 10.1016/j.immuni.2013.08.003 Carvalho, A.; Cunha, C.; Bozza, S.; Moretti, S.; Massi-Benedetti, C.; Bistoni, F.; Aversa, F.; Romani, L.. "Immunity and tolerance to fungi in hematopoietic transplantation: Principles and perspectives". Frontiers in Immunology 3 JUN (2012): 156. 10.3389/fimmu.2012.00156 Carvalho, A.; Cunha, C.; Bistoni, F.; Romani, L.. "Immunotherapy of aspergillosis". Clinical Microbiology and Infection 18 2 (2012): 120-125. 10.1111/j.1469-0691.2011.03681.x Carvalho, A.; De Luca, A.; Bozza, S.; Cunha, C.; D'Angelo, C.; Moretti, S.; Perruccio, K.; et al. "TLR3 essentially promotes protective class I-restricted memory CD8 T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients". Blood 119 4 (2012): 967-977. 10.1182/blood-2011-06-362582 Carvalho, A.; Cunha, C.; Almeida, A.J.; Osório, N.S.; Saraiva, M.; Teixeira-Coelho, M.; Pedreiro, S.; et al. "The rs5743836 polymorphism in TLR9 confers a population-based increased risk of non-Hodgkin lymphoma". Genes and Immunity 13 2 (2012): 197-201. 10.1038/gene.2011.59 De Luca, A.; Iannitti, R.G.; Bozza, S.; Beau, R.; Casagrande, A.; D'Angelo, C.; Moretti, S.; et al. "CD4⁺T cell vaccination overcomes defective cross-presentation of fungal antigens in a mouse model of chronic granulomatous disease". Journal of Clinical Investigation 122 5 (2012): 1816-1831. 10.1172/JCI60862 Carvalho, A.; Giovannini, G.; De Luca, A.; D'Angelo, C.; Casagrande, A.; Iannitti, R.G.; Ricci, G.; Cunha, C.; Romani, L.. "Dectin-1 isoforms contribute to distinct Th1/Th17 cell activation in mucosal candidiasis". Cellular and Molecular Immunology 9 3 (2012): 276-286. 10.1038/cmi.2012.1 Cunha, C.; Carvalho, A.; Esposito, A.; Bistoni, F.; Romani, L.. "DAMP signaling in fungal infections and diseases". Frontiers in Immunology 3 SEP (2012): 286. 10.3389/fimmu.2012.00286 Carvalho, A.; Cunha, C.; Iannitti, R.G.; Casagrande, A.; Bistoni, F.; Aversa, F.; Romani, L.. "Host defense pathways against fungi: The basis for vaccines and immunotherapy". Frontiers in Microbiology 3 MAY (2012): 176. 10.3389/fmicb.2012.00176 Iannitti, R.G.; Carvalho, A.; Romani, L.. "From memory to antifungal vaccine design". Trends in Immunology 33 9 (2012): 467-474. 10.1016/j.it.2012.04.008 Cunha, C.; Carvalho, A.. "Host genetics and invasive fungal diseases: Towards improved diagnosis and therapy?". Expert Review of Anti-Infective Therapy 10 3 (2012): 257-259. 10.1586/eri.12.3 Carvalho, A.; Cunha, C.; Iannitti, R.G.; De Luca, A.; Giovannini, G.; Bistoni, F.; Romani, L.. "Inflammation in aspergillosis: The good, the bad, and the therapeutic". Annals of the New York Academy of Sciences 1273 1 (2012): 52-59. 10.1111/j.1749-6632.2012.06754.x Cunha, C.; Giovannini, G.; Pierini, A.; Bell, A.S.; Sorci, G.; Riuzzi, F.; Donato, R.; et al. "Genetically-determined hyperfunction of the S100B/RAGE axis is a risk factor for aspergillosis in stem cell transplant recipients". PLoS ONE 6 11 (2011): e27962. 10.1371/journal.pone.0027962 Cunha, C.; Rodrigues, F.; Zelante, T.; Aversa, F.; Romani, L.; Carvalho, A.. "Genetic susceptibility to aspergillosis in allogeneic stem-cell transplantation". Medical Mycology 49 SUPPL. 1 (2011): S137-S143. 10.3109/13693786.2010.508797 Cunha, C.; Aversa, F.; Bistoni, G.; Casagrande, A.; Rodrigues, F.; Romani, L.; Carvalho, A.. "Immunogenetic profiling to predict risk of invasive fungal diseases: Where are we now?". Immunological Investigations 40 7-8 (2011): 723-734. 10.3109/08820139.2011.586395 Carvalho, A.; Cunha, C.; Romani, L.. "Immunity and tolerance to infections in experimental hematopoietic transplantation". Best Practice and Research: Clinical Haematology 24 3 (2011): 435-442. 10.1016/j.beha.2011.04.006 Carvalho, A.; Osório, N.S.; Saraiva, M.; Cunha, C.; Almeida, A.J.; Teixeira-Coelho, M.; Ludovico, P.; et al. "The C allele of rs5743836 polymorphism in the human TLR9 promoter links IL-6 and TLR9 up-regulation and confers increased B-cell proliferation". PLoS ONE 6 11 (2011): e28256. 10.1371/journal.pone.0028256 Cunha, C.; Di Ianni, M.; Bozza, S.; Giovannini, G.; Zagarella, S.; Zelante, T.; D'Angelo, C.; et al. "Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of antifungal immunity". Blood 116 24 (2010): 5394-5402. 10.1182/blood-2010-04-279307 Cunha, C.; Romani, L.; Carvalho, A.. "Cracking the Toll-like receptor code in fungal infections". Expert Review of Anti-Infective Therapy 8 10 (2010): 1121-1137. 10.1586/eri.10.93 Bonifazi, P.; D'Angelo, C.; Zagarella, S.; Zelante, T.; Bozza, S.; De Luca, A.; Giovannini, G.; et al. "Intranasally delivered siRNA targeting PI3K/Akt/mTOR inflammatory pathways protects from aspergillosis". Mucosal Immunology 3 2 (2010): 193-205. 10.1038/mi.2009.130 Carvalho, A.; Cunha, C.; Pasqualotto, A.C.; Pitzurra, L.; Denning, D.W.; Romani, L.. "Genetic variability of innate immunity impacts human susceptibility to fungal diseases". International Journal of Infectious Diseases 14 6 (2010): e460-e468. 10.1016/j.ijid.2009.06.028 Carvalho, A.; Cunha, C.; Di Ianni, M.; Pitzurra, L.; Aloisi, T.; Falzetti, F.; Carotti, A.; et al. "Prognostic significance of genetic variants in the IL-23/Th17 pathway for the outcome of T cell-depleted allogeneic stem cell transplantation". Bone Marrow Transplantation 45 11 (2010): 1645-1652. 10.1038/bmt.2010.28 De Luca, A.; Bozza, S.; Zelante, T.; Zagarella, S.; D'Angelo, C.; Perruccio, K.; Vacca, C.; et al. "Non-hematopoietic cells contribute to protective tolerance to Aspergillus fumigatus via a TRIF pathway converging on IDO". Cellular and Molecular Immunology 7 6 (2010): 459-470. 10.1038/cmi.2010.43 Carvalho, A.; Cunha, C.; Carotti, A.; Aloisi, T.; Guarrera, O.; Di Ianni, M.; Falzetti, F.; et al. "Polymorphisms in Toll-like receptor genes and susceptibility to infections in allogeneic stem cell transplantation". Experimental Hematology 37 9 (2009): 1022-1029. 10.1016/j.exphem.2009.06.004 Almeida, A.J.; Cunha, C.; Carmona, J.A.; Sampaio-Marques, B.; Carvalho, A.; Malavazi, I.; Steensma, H.Y.; et al. "Cdc42p controls yeast-cell shape and virulence of Paracoccidioides brasiliensis". Fungal Genetics and Biology 46 12 (2009): 919-926. 10.1016/j.fgb.2009.08.004 Carvalho, A.; Santos, M.; Maciel, P.; Rodrigues, F.. "T-1237C polymorphism of TLR9 gene is not associated with multiple sclerosis in the Portuguese population". Multiple Sclerosis 14 4 (2008): 550-552. 10.1177/1352458507084594 Carvalho, A.; Pasqualotto, A.C.; Pitzurra, L.; Romani, L.; Denning, D.W.; Rodrigues, F.. "Polymorphisms in toll-like receptor genes and susceptibility to pulmonary aspergillosis". Journal of Infectious Diseases 197 4 (2008): 618-621. 10.1086/526500 Carvalho, A.; Costa-De-Oliveira, S.; Martins, M.L.; Pina-Vaz, C.; Rodrigues, A.G.; Ludovico, P.; Rodrigues, F.. "Multiplex PCR identification of eight clinically relevant Candida species". Medical Mycology 45 7 (2007): 619-627. 10.1080/13693780701501787 Azevedo, M.-M.; Carvalho, A.; Pascoal, C.; Rodrigues, F.; Cássio, F.. "Responses of antioxidant defenses to Cu and Zn stress in two aquatic fungi". Science of the Total Environment 377 2-3 (2007): 233-243. 10.1016/j.scitotenv.2007.02.027 Osório, N.S.; Carvalho, A.; Almeida, A.J.; Padilla-Lopez, S.; Leão, C.; Laranjinha, J.; Ludovico, P.; Pearce, D.A.; Rodrigues, F.. "Nitric oxide signaling is disrupted in the yeast model for Batten disease". Molecular Biology of the Cell 18 7 (2007): 2755-2767. 10.1091/mbc.E06-11-1053 Almeida, A.J.; Carmona, J.A.; Cunha, C.; Carvalho, A.; Rappleye, C.A.; Goldman, W.E.; Hooykaas, P.J.; et al. "Towards a molecular genetic system for the pathogenic fungus Paracoccidioides brasiliensis". Fungal Genetics and Biology 44 12 (2007): 1387-1398. 10.1016/j.fgb.2007.04.004 Carvalho, A.; Marques, A.; Maciel, P.; Rodrigues, F.. "Study of disease-relevant polymorphisms in the TLR4 and TLR9 genes: A novel method applied to the analysis of the Portuguese population". Molecular and Cellular Probes 21 4 (2007): 316-320. 10.1016/j.mcp.2007.03.005
Preface / Postscript	Carvalho, A.. "Preface". Preface to Immunogenetics of Fungal Diseases. Springer International Publishing. 2017.
Thesis / Dissertation	Carvalho, Agostinho Albérico Rodrigues de. "Management of fungal infections: diagnosis and human genetic susceptibility". PhD, Universidade do Minho Escola de Medicina, 2008. http://hdl.handle.net/1822/8163.

Intellectual property

Patent

Carvalho, Agostinho; Rodrigues, Fernando. 2006. "DNA fragments, primers, kits, and methods for amplification, the detection and identification of clinically relevant Candida species". Portugal.
Expired

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2023/11	Metabolic regulation of granulomatous inflammation in sarcoidosis	39º Congresso de Pneumologia Portuguese Society of Pneumology (Albufeira, Portugal)
2023/10	Multi-omics for early diagnosis and risk stratification for viral-associated pulmonary aspergillosis	11th Trends in Medical Mycology European Confederation of Medical Mycology (ECMM) (Athens, Greece)
2023/09	Molecular mechanisms of immunity to viral-associated pulmonary aspergillosis	18th Scientific Meeting of the Nordic Society for Medical Mycology Nordic Society for Medical Mycology (Copenhagen, Denmark)
2023/06	Model systems to elucidate humoral innate immunity during granuloma formation in sarcoidosis	International Conference of the World Association of Sarcoidosis and Other Granulomatous Diseases – WASOG 2023 World Association of Sarcoidosis and Other Granulomatous Diseases (WASOG) (Stockholm, Sweden)
2023/06	Metabolic circuits of immune regulation and function in aspergillosis	MycoTalks MRC Centre for Medical Mycology (Exeter, United Kingdom)
2023/05	Omics approaches to study host-fungus-microbiota interactions	Host-Fungus Interactions and Virulence Centro de Biologia Molecular e Ambiental (CBMA), University of Minho (Braga, Portugal)
2023/03	Metabolic determinants of innate immunity to fungal infection	Seminars at the Department of Mycology Institut Pasteur (Paris, France)
2023/01	Genetic determinants of C-type lectin receptor function in fungal infection	14th International Meeting of the Portuguese Carbohydrate Group – GLUPOR 14 Portuguese Society of Chemistry (Caparica, Portugal)
2023/01	Genetic determinants of immunometabolic responses to fungal infection	Gordon Research Conference “Immunology of Fungal Infections” Gordon Research Conferences (Galveston, United States)
2022/10	Lung hybrid neutrophils and subsequent NETosis are protective in COVID-19-associated pulmonary aspergillosis	IDWeek 2022 (Washington, United States)
2022/10	Immunometabolic regulation of antifungal immunity	19ª Semana Nacional de Ciência e Tecnologia (SNCT) Brazilian Society for Immunology (Virtual)
2022/10	Pathogenesis of viral-fungal coinfections	5th PhDay: 'Building Paths: The Science Behind Us' Instituto de Investigação e Inovação em Saúde (i3S) (Porto, Portugal)
2022/09	Pathogenesis of virus-associated fungal infections	Myk2022 German-speaking Mycological Society (DMykG) & Austrian Society of Medical Mycology (ÖGMM) (Vienna, Austria)
2022/09	Antifungal resistance mechanisms and more	ECMM Webinar Series European Confederation of Medical Mycology (ECMM) (Netherlands)
2022/07	Emerging topics in host-fungus interactions	International Symposium Brazil/Colombia on Fungal Infections UNESP and Universidad de Antioquia (São Paulo, Brazil)
2022/05	Metabolic control of immune cell function during fungal infection	FEBS Advanced Lecture Course HFP2022: “Molecular Mechanisms of Host-Pathogen Interactions and Virulence in Human Fungal Pathogens” Federation of European Biochemical Societies (La-Colle-sur-Loup, France)
2022/04	Role of pathogen and host pathophysiology in fungal diagnosis	32nd European Congress of Clinical Microbiology and Infectious Diseases European Society of Clinical Microbiology and Infectious Diseases (Lisbon, Portugal)
2022/04	Myeloid immunity-driven gene expression profiling in bronchoalveolar lavage fluid of influenza- and COVID-19-associated pulmonary aspergillosis	32nd European Congress of Clinical Microbiology and Infectious Diseases European Society of Clinical Microbiology and Infectious Diseases (Lisbon, Portugal)
2022/03	Immunogenetics of infection in stem-cell transplantation	12th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies Portuguese Society for Stem Cells and Cell Therapies (Braga, Portugal)
2022/03	Host response and risk factors for fungal disease in the ICU and during COVID-19 infection	32nd European Congress of Clinical Microbiology and Infectious Diseases - Pre-ECCMID Day 2: COVID-19 European Society of Clinical Microbiology and Infectious Diseases (Lisbon, Portugal)
2022/02	Immunometabolic regulation of anti-fungal immunity	Manchester Infection Seminar Series 2021/2022 Division of Evolution, Infection and Genomics (EIGEN) and the Antimicrobial Resistance (AMR) Network (Manchester, United Kingdom)
2021/11	Immunometabolic regulation of granulomatous inflammation in sarcoidosis	37º Congresso de Pneumologia Portuguese Society of Pneumology (Albufeira, Portugal)
2021/10	Top 10 Papers: Basic / immunology / genomics	10th Trends in Medical Mycology (Aberdeen, United Kingdom)
2021/07	Host genetic signature of susceptibility to fungal disease	31st European Congress of Clinical Microbiology and Infectious Diseases European Society of Clinical Microbiology and Infectious Diseases (Vienna, Austria)
2021/06	Host susceptibility to pathogenic fungi	Mycology 2021 British Society for Medical Mycology (London, United Kingdom)
2021/06	Calcium sequestration by fungal melanin reprograms macrophage metabolism toward glycolysis and antifungal immunity	Mycology 2021 British Society for Medical Mycology (London, United Kingdom)
2021/06	Toward new insights into the role of the lung microbiota in invasive pulmonary aspergillosis	Mycology 2021 British Society for Medical Mycology (London, United Kingdom)
2021	Immunometabolic regulation of granulomatous inflammation in sarcoidosis	Ciência Falada Life and Health Sciences Research Institute (ICVS) (Braga, Portugal)
2020/02	Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity	9th Advances Against Aspergillosis and Mucormycosis (Lugano, Switzerland)
2019/10	Metabolic regulation of innate immunity to Aspergillus fumigatus	9th Trends in Medical Mycology (Nice, France)
2019/10	Antimold immune response: the impact of the host, the pathogen, and translational implications	9th Trends in Medical Mycology (Nice, France)
2019/06	Diagnosis of aspergillosis based on metabolomics data - application of relative expression analysis-RXA to minimize interindividual metabolic differences	Metabolomics 2019 - 15th Annual Conference of the Metabolomics Society (The Hague, Netherlands)
2019/06	Novel molecular mechanisms regulating innate antifungal immunity	GENYO Seminars Centro Pfizer - Universidad de Granada - Junta de Andalucía de Genómica e Investigación Oncológica (Granada, Spain)
2019/05	Innate regulation of granulomatous inflammation in sarcoidosis	The Frontiers of Research in Interstitial Lung Disease (Braga, Portugal)
2019/05	Genetic regulation of human antifungal immunity	iBiMED Seminars Universidade de Aveiro Instituto de Biomedicina (Aveiro, Portugal)
2019/04	Debate: Shouldn't we be measuring the host¿s response to IFI? - proposer	29th European Congress of Clinical Microbiology and Infectious Diseases (Amsterdam, Netherlands)
2018/12	Genetic regulation of susceptibility to infection in stem-cell transplantation	Seminars at the Faculty of Medicine - University of Coimbra Universidade de Coimbra Faculdade de Medicina (Coimbra, Portugal)
2018/11	Regulação da inflamação na sarcoidose pela pentraxina-3 (PTX3)	XXXIV Congresso de Pneumologia (Albufeira, Portugal)
2018/10	Translating the host-microbiota interaction into risk assessment of fungal diseases	Mérieux Research Grant Meeting 2018 (Annecy, France)
2018/10	Inhibition of host neuraminidase increases susceptibility to invasive pulmonary aspergillosis	IDWeek 2018 (Washington, United States)
2018/10	The genetic architecture of human antifungal immunity	VII Retiro Anual do PhDOC Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde (Braga, Portugal)
2018/09	The long pentraxin-3 restrains inflammation in sarcoidosis by regulating leukocyte recruitment and granuloma formation	Symposium 'New Frontiers in Innate Immunity and Inflammation' (Cluj-Napoca, Romania)
2018/07	New insights in diagnosis and immunopathology of aspergillosis	20th Congress of the International Society for Human and Animal Mycology (ISHAM) (Amsterdam, Netherlands)
2018/05	DNA polymorphism and fungal infection after HSCT	CRYOSTEM HTC Day 2018 (Paris, France)
2018/03	Novel genetic and molecular mechanisms regulating innate antifungal immunity	Seminars at the Department of Mycology Institut Pasteur (Paris, France)
2018/02	Genetics of aspergillosis	8th Advances Against Aspergillosis (Lisbon, Portugal)
2018/02	IL-10 overexpression in vivo promotes susceptibility to aspergillosis by suppressing innate and adaptive pulmonary antifungal immunity	8th Advances Against Aspergillosis (Lisbon, Portugal)
2017/10	Translating the host-microbiota interaction into risk assessment of fungal diseases	Mérieux Research Grant Meeting 2017 (Paris, France)
2017/10	The microbiome-metabolome crosstalk in the pathogenesis of invasive aspergillosis	8th Trends in Medical Mycology (TIMM) (Belgrade, Serbia)
2017/06	Inflammasome-mediated regulation of antifungal immunity in hematological patients	22nd European Hematology Association (EHA) Meeting (Madrid, Spain)
2017/06	Novel molecular mechanisms regulating innate antifungal immunity	XLIII Annual Meeting of the Portuguese Society for Immunology (Porto, Portugal)
2017/06	Human genetic susceptibility to invasive aspergillosis	Host-Fungus Interactions and Virulence Centro de Biologia Molecular e Ambiental (CBMA), University of Minho (Braga, Portugal)
2017/05	The genetic architecture of innate antifungal immunity	HFP2017 Advanced Lecture Course “Molecular Mechanisms of Host-Pathogens Interactions and Virulence in Human Fungal Pathogens (La-Colle-sur-Loup, France)
2016/11	PTX3 regula a inflamação granulomatosa na sarcoidose ao controlar a dinâmica das células T	XXXII Congresso de Pneumologia (Albufeira, Portugal)
2016/07	Impact of fungal infections in immunosuppressed patients	Encontro Ciência '16 (Lisbon, Portugal)
2016/06	Who paves the way for fungi: genes or doctors? - Iatrogenic immunodeficiencies	ASM Microbe 2016 (Boston, United States)
2016/03	Human genetic variation in antifungal immunity and inflammation	Invasive Mycoses in Haematological Malignancies X - IMIHM X (Würzburg, Germany)
2016/03	Human genetic variation in antifungal immunity and inflammation	Monday Lectures at IMM Instituto de Medicina Molecular João Lobo Antunes (Lisboa, Portugal)
2016/02	Human genetic variation in antifungal immunity and inflammation	FEBS Advanced Practical Course “State-of-the-art infection models to study molecular mechanisms of human fungal infections” (Jena, Germany)
2015/12	Deciphering genetic susceptibility to fungal infection: from biological understanding to clinical intervention	6th Joint Congress of Microbiology and Biotechnology MicroBiotec’15 (Évora, Portugal)
2015/10	Complex host genetic susceptibility to fungal infection	7th Trends in Medical Mycology (TIMM) (Lisbon, Portugal)
2015/10	Functional genomics of aspergillosis in stem cell transplantation	ASPOMM Meeting “Local Mycology Meeting” - 7th Trends in Medical Mycology (TIMM) (Lisbon, Portugal)
2015/09	PTX3-based genetic testing for risk of aspergillosis	Myk2015 (Jena, Germany)
2015/02	Genetic polymorphisms in the cytokine and chemokine system: importance for infections	16th International Symposium of KU Leuven - “Pulmonary Infections” (Leuven, Belgium)
2014/07	Host genetic signatures of susceptibility to fungal disease	4th Central European Summer Course and 1st Rising Stars in Mycology Workshop (Szeged, Hungary)
2014/05	Genetic susceptibilities/genetic markers to invasive fungal disease	5th MSD Forum on Invasive Fungal Infections (Rome, Italy)
2014/04	The rs3739319 polymorphism in IDO1 is linked with Aspergillus fumigatus colonization in cystic fibrosis patients	ALLFUN Final Meeting (Salerno, Italy)
2014/02	Functional aspects of IA-linked genetic variants	6th Advances Against Aspergillosis (Madrid, Spain)
2014/02	Genetics of tryptophan catabolism and host defense against invasive aspergillosis	Gordon Research Conference “Biology of Acute Respiratory Infection” (Lucca, Italy)
2013/11	Host genomics of fungal diseases: en route to improved diagnosis and therapy	Singapore/Italy Joint Workshop on Cellular and Molecular Medicine (Singapore, Singapore)
2013/09	Immunogenetics of human fungal infections	Microbial Pathogenesis and Immunity (Perugia, Italy)
2013/09	Immunogenetics of susceptibility to invasive fungal infections	EBMT Immunobiology Working Party Meeting 2013 (Perugia, Italy)
2013/09	Genetic risk factors for fungal infections	6th International Congress on Sepsis and Multiorgan Dysfunction (Weimar, Germany)
2013/08	Human susceptibility to invasive aspergillosis: from genes to function	15th International Congress of Immunology (ICI) SM5 Satellite Meeting (Perugia, Italy)
2013/08	Immunity and tolerance to fungi: the contribution of gut microbiota via tryptophan catabolism	15th International Congress of Immunology (ICI) (Milan, Italy)
2013/08	The role of the NLRP3 inflammasome in aspergillosis	15th International Congress of Immunology (ICI) SM5 Satellite Meeting (Perugia, Italy)
2013/08	Genetic variants in donor PTX3 impair antifungal immunity and predispose to invasive aspergillosis after stem cell transplantation	15th International Congress of Immunology (ICI) (Milan, Italy)
2013/06	Functional genetics of susceptibility to aspergillosis in stem cell transplantation	Fungal Diseases in Hematology: Translating Basic Science into Clinical Practice (Parma, Italy)
2013/01	Humoral immunity and immunogenetics of aspergillosis: old friends revisited	Gordon Research Conference “Immunology of Fungal Infections” (Galveston, United States)
2013/01	NLRP3 and susceptibility to pulmonary aspergillosis	Gordon Research Conference “Immunology of Fungal Infections” (Galveston, United States)
2012/11	Genomica funzionale della aspergillosi	XI Congresso Nazionale FIMUA (Catania, Italy)
2012/10	Predittori genetici di suscettibilità alle infezioni fungine nei pazienti	Laboratorio SEIFEM: Nuove Prospettive in Tema di Infezioni nel Paziente Emopatico (Rome, Italy)
2012/10	The impact of genetic variants in the Th17 inflammatory pathway to the susceptibility to infections in patients with chronic granulomatous disease	15th Biennial Meeting of the European Society for Immunodeficiencies (Florence, Italy)
2012/09	Genetic deficiency of PTX3 and invasive aspergillosis in stem cell transplantation	ALLFUN 2nd Annual Meeting (Borgo Scopeto, Italy)
2012/07	Genetic susceptibility to aspergillosis: principles and perspectives	Seminars at CHUV Centre Hospitalier Universitaire Vaudois (Lausanne, Switzerland)
2012/06	Polimorfismi genetici e prognosi	Mieloma Multiplo: From the Bench to the Bedside (Parma, Italy)
2012/05	Immunogenetics of aspergillosis: towards improved diagnosis and therapy	ESF Workshop “Omics and Aspergillosis: Past and Future” (Deshaies/Guadeloupe, France)
2012/05	Fattori di rischio biologici	Il Percorso Diagnostico-Terapeutico del Paziente Ematologico con Infezione Fungina Invasiva (Turin, Italy)
2012/03	Genetic susceptibility to IA: the Perugia study results	Invasive Mycoses in Haematological Malignancies VI – IMIHM VI (Würzburg, Germany)
2012/01	Functional impact of genetic polymorphisms in invasive aspergillosis	Genomics in Hematology (Perugia, Italy)
2011/11	Fattori di rischio genetici	Trapianto e Infezioni Fungine Invasive (Perugia, Italy)
2011/10	Genomic risk factors	Russian-Italian Workshop “Invasive fungal infections in high-risk patients: a Perugia perspective” (Perugia, Italy)
2011/05	Diagnosi delle infezioni fungine: immunologia e aspetti genetici	Aggiornamenti in Terapia Antifungina: la Parola agli Esperti (Treviso, Italy)
2011/05	The contribution of the DAMP/RAGE axis to immunity to Aspergillus fumigatus: from mice to humans	4th FEBS Advanced Lecture Course “Human Fungal Pathogens: Molecular Mechanisms of Host-Pathogen Interactions and Virulence” (La-Colle-sur-Loup, France)
2011/04	Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of antifungal immunity	37th Annual Meeting of the European Group for Blood and Marrow Transplantation (Paris, France)
2011/01	Cracking the genetic code for susceptibility to aspergillosis in allogeneic stem cell transplantation	Gordon Research Conference “Immunology of Fungal Infections” (Galveston, United States)
2010/10	Polimorfismi e aspetti non-HLA correlati: utilità nella selezione donatore/ricevente nel trapianto allogenico? Per la profilassi? Per le colonizzazioni?	Le Infezioni Fungine Invasive nel Paziente Ematologico: Percorsi Diagnostico-Terapeutici Multidisciplinari (Rome, Italy)
2010/09	Cracking the TLR code to harness natural immunity against infections in HSCT	EBMT Immunobiology Working Party Meeting 2010 (Perugia, Italy)
2010/09	The Y238X polymorphism in dectin-1 is associated with risk for aspergillosis in stem cell transplantation	10° Congresso Nazionale FIMUA (Milan, Italy)
2010/02	Genetic susceptibility to aspergillosis in allogeneic stem cell transplantation	4th Advances Against Aspergillosis (Rome, Italy)
2009/11	Polymorphisms in immune genes and susceptibility to infections in allogeneic stem cell transplantation	EBMT Immunobiology Working Party Meeting 2009 (Perugia, Italy)
2003/09	Saccharomyces cerevisiae ¿btn1 as a model to study the neurodegenerative Batten disease	XXII ECCO Meeting (Braga, Portugal)
2003/05	Mitochondrial and cell cycle responses to oxidative stress by the mutant ¿btn1 of Saccharomyces cerevisiae, the yeast model of Batten disease	XI Jornadas de Leveduras do Professor Nicolau van Uden (Bragança, Portugal)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2024 - Current	Immunometabolic regulation of granulomatous inflammation in sarcoidosis Supervisor of Relber A. Gonçales	Post-doctoral Researcher (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2024 - Current	Dissecting Alternaria alternata proteome towards novel tools to manage respiratory allergies Co-supervisor of Daniela Calheiros	PhD in Health Sciences (PhD) Universidade de Coimbra Faculdade de Medicina, Portugal
2024 - Current	Dissecting the role of interleukin-37 in the metabolic regulation of antifungal immunity Co-supervisor of Inês Caldeira	PhD in Health Sciences (PhD) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2024 - Current	Metabolic regulation of granulomatous inflammation by tryptophan catabolism Supervisor of Marcela Oliveira	Phd in Health Sciences (PhD) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2023 - Current	Metabolic circuits of immune regulation and function during fungal infection Supervisor of Raquel Fernandes	PhD in Health Sciences (PhD) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2023 - Current	Metabolic control of immune cell function during fungal infection Supervisor of Rita Silva-Gomes	Post-doctoral Researcher (Other) Universidade do Minho Instituto de Investigacao em Ciencias da Vida e Saude, Portugal
2023 - Current	Metabolic control of immune cell function in respiratory fungal disease Co-supervisor of Diana Santos-Ribeiro	Post-doctoral Researcher (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2020 - Current	Viral-associated pulmonary aspergillosis: new perspectives to enable host-directed medicine Co-supervisor of Simon Feys	PhD in Biomedical Sciences (PhD) Katholieke Universiteit Leuven Departement Microbiologie Immunologie en Transplantatie, Belgium
2023 - 2023	A transdisciplinary approach to the identification of personalized biomarkers and therapeutic targets for chronic pulmonary aspergillosis Supervisor of Diana Santos-Ribeiro	Post-doctoral Researcher (Other) Universidade do Minho Instituto de Investigacao em Ciencias da Vida e Saude, Portugal
2022 - 2023	A transdisciplinary approach to the identification of personalized biomarkers and therapeutic targets for chronic pulmonary aspergillosis Supervisor of Rita Silva-Gomes	Post-doctoral Researcher (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2022 - 2023	The genetic architecture of the immune response to Aspergillus fumigatus: from biological understanding to therapeutic intervention Supervisor of Relber Gonçales	Post-doctoral Researcher (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2022 - 2023	A transdisciplinary approach to the identification of personalized biomarkers and therapeutic targets for chronic pulmonary aspergillosis Supervisor of Marcela Oliveira	Research Assistant (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2022 - 2023	Dissecting the role of immunometabolism in granuloma formation in sarcoidosis Supervisor of Ana Baptista	MSc in Health Sciences (Master) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018 - 2023	Metabolic regulation of antifungal immunity: from basic mechanisms to clinical translation Supervisor of Samuel Gonçalves	PhD in Health Sciences (PhD) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018 - 2023	Genetic and molecular determinants of susceptibility to aspergillosis Supervisor of Daniela Antunes	PhD in Ageing and Chronic Diseases (PhDOC) (PhD) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018 - 2023	Innate regulation of antifungal immunity in chronic pulmonary aspergillosis Supervisor of Cláudio Oliveira	PhD in Health Sciences (PhD) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2022 - 2022	The host-microbiota interaction in fungal diseases: towards biomarker discovery and therapy Co-supervisor of Joana Rocha	Post-doctoral Researcher (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2022 - 2022	Host-directed medicine in invasive fungal infection Supervisor of Raquel Fernandes	Research Assistant (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2021 - 2022	Innate regulation of inflammation in sarcoidosis Supervisor of Raquel Fernandes	Research Assistant (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019 - 2022	Innate regulation of inflammation in sarcoidosis Supervisor of Relber Gonçales	Post-doctoral Researcher (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018 - 2022	Immunometabolic pathways in the regulation of trained immunity Co-supervisor of Anaísa Ferreira	PhD in Basic and Applied Biology (GABBA) (PhD) Radboud Universiteit, Netherlands Universidade do Minho Escola de Medicina, Portugal
2020 - 2021	Innate regulation of inflammation in sarcoidosis Supervisor of Sara Ferreira	Research Assistant (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2020 - 2021	The host-microbiota interaction in fungal diseases: towards biomarker discovery and therapy Co-supervisor of Carolina Pereira	Research Assistant (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2020 - 2021	The role of complement activation in the pathogenesis and progression of sarcoidosis Supervisor of Bárbara Barros	Integrated Msc in Medicine (Master) Universidade do Minho Escola de Medicina, Portugal
2020 - 2021	A transdisciplinary approach to the identification of personalized biomarkers and therapeutic targets for chronic pulmonary aspergillosis Supervisor of Teresa L. Silva	Post-doctoral Researcher (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019 - 2021	Immunometabolic regulation of antifungal immunity by itaconate Co-supervisor of Carolina Pereira	MSc in Health Sciences (Master) Universidade do Minho Escola de Medicina, Portugal
2019 - 2021	HIF-1a-mediated regulation of antifungal immunity in chronic pulmonary obstructive disease Supervisor of Sara Ferreira	MSc in Health Sciences (Master) Universidade do Minho Escola de Medicina, Portugal
2019 - 2021	The host-microbiota interaction in fungal diseases: towards biomarker discovery and therapy Co-supervisor of Anais Hérivaux	Post-doctoral Researcher (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019 - 2020	New avenues for the development of personalized medical interventions for neurological, oncologic and surgical disorders Supervisor of Teresa L. Silva	Post-doctoral Researcher (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019 - 2020	New avenues for the development of personalized medical interventions for neurological, oncologic and surgical disorders Supervisor of Patrícia Terra	Post-doctoral Researcher (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018 - 2019	Dissecting pentraxin-3 role in the modulation of multiple sclerosis Co-supervisor of Joana Sá	MSc in Health Sciences (Master) Universidade do Minho Escola de Medicina, Portugal
2018 - 2019	The role of inflammasome-autophagy crosstalk in fungal infection Supervisor of Cláudia Campos	Research Assistant (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018 - 2019	The role of inflammasome-autophagy crosstalk in fungal infection Supervisor of Cláudia Rodrigues	Research Assistant (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018 - 2019	The role of inflammasome-autophagy crosstalk in fungal infection Supervisor of Cláudio Oliveira	Research Assistant (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017 - 2018	Genetic variation in pentraxin-3 and susceptibility to cytomegalovirus reactivation Supervisor of Francisco Silva	Integrated MSc in Medicine (Master) Universidade do Minho Escola de Medicina, Portugal
2017 - 2018	Immunometabolic control of antifungal innate immunity Co-supervisor of Cláudia Rodrigues	MSc in Health Sciences (Master) Universidade do Minho Escola de Medicina, Portugal
2017 - 2018	Innate regulation of granulomatous inflammation in sarcoidosis Supervisor of Cláudia Campos	MSc in Health Sciences (Master) Universidade do Minho Escola de Medicina, Portugal
2017 - 2018	Influence of CARD9 genetic variants to the risk of invasive aspergillosis in patients undergoing hematopoietic stem cell transplantation Supervisor of Diogo Ribeiro	Integrated MSc in Medicine (Master) Universidade do Minho Escola de Medicina, Portugal
2017 - 2018	The role of inflammasome-autophagy crosstalk in fungal infection Supervisor of Samuel Gonçalves	Research Assistant (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2016 - 2017	Translating the host-microbiota interaction into risk assessment of invasive aspergillosis Co-supervisor of Samuel Gonçalves	MSc in Health Sciences (Master) Universidade do Minho Escola de Medicina, Portugal
2015 - 2016	Genetic variation in inflammasome genes and risk of invasive fungal disease in stem-cell transplant recipients Supervisor of Diana Matos	Integrated MSc in Medicine (Master) Universidade do Minho Escola de Medicina, Portugal
2015 - 2016	Genetic variability of human myeloperoxidase and aspergillosis Supervisor of Sergio Sasaki	Post-doctoral Researcher (Other) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2012 - 2016	The role of LKB1-AMPK pathway on acute myeloid leukemia Co-supervisor of Ângela Fernandes	PhD in Ageing and Chronic Disease (PhDOC) (PhD) Universidade do Minho Escola de Medicina, Portugal
2009 - 2012	The S100B/RAGE danger signaling pathway in murine and human aspergillosis Supervisor of Gloria Giovannini	PhD in Biology and Experimental Medicine (PhD) Università degli Studi di Perugia Dipartimento di Medicina Sperimentale, Italy

Event organisation

	Event name Type of event (Role)	Institution / Organization
2022 - 2022	Post-graduation course "Fundamentals in Immunology and Infection" - 14th edition (2022/09/12 - 2022/09/30) Other (Member of the Organising Committee)	Universidade do Minho Escola de Medicina, Portugal
2020 - 2022	2022 FEBS Advanced Lecture Course on Human Fungal Pathogens (HFP2022) (2022/05/14 - 2022/05/20) Conference (Member of the Scientific Committee)	Federation of European Biochemical Societies, United Kingdom
2021 - 2021	International Immunology Day: Advances on the Immune Responses during COVID-19 (2021/04/29 - 2021/04/29) Symposium (Member of the Organising Committee)	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021 - 2021	Post-graduation course "Fundamentals in Immunology and Infection" - 13th edition (2021/09/27 - 2021/10/15) Other (Member of the Organising Committee)	Universidade do Minho Escola de Medicina, Portugal
2020 - 2021	XLVI Annual Meeting of the Portuguese Society for Immunology (2021/05/20 - 2021/05/21) Congress (Member of the Organising Committee)	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018 - 2019	The Frontiers of Research in Interstitial Lung Diseases (2019/05/10) Symposium (Co-organisor)	Universidade do Minho Escola de Medicina, Portugal
2015 - 2019	ICVS International Seminar Series (2015 - 2019) Seminar (Member of the Organising Committee)	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2014 - 2015	XLI Annual Meeting of the Portuguese Society for Immunology (2015/10/26 - 2015/10/28) Congress (Member of the Organising Committee)	Universidade do Minho Escola de Medicina, Portugal
2014 - 2015	Postgraduation Course "Autophagy in Health and Disease: Conceptual and Methodological Advances" (2015/04/07 - 2015/04/10) Other (Member of the Organising Committee)	Universidade do Minho Escola de Medicina, Portugal
2012 - 2013	15th International Congress of Immunology (ICI) SM5 Satellite Meeting (2013/08/29 - 2013/08/30) Congress (Member of the Organising Committee)	Università degli Studi di Perugia Dipartimento di Medicina Sperimentale, Italy
2012 - 2013	Fungal Diseases in Hematology - Translating Basic Science into Clinical Practice (2013/04/26 - 2013/04/28) Symposium (Member of the Organising Committee)	Azienda Ospedaliero-Universitaria di Parma, Italy
2011 - 2012	Genomics in Hematology (2012/01/29 - 2012/01/31) Symposium (Member of the Organising Committee)	Università degli Studi di Perugia Dipartimento di Medicina Sperimentale, Italy
2006 - 2007	Postgraduation Course "Invasive Infections by Aspergillus spp." (2007/11/21 - 2007/11/23) Other (Member of the Organising Committee)	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2003 - 2004	Postgraduation Course "Relevant Fungi in Clinical Practice: From Biology to Pathology and Treatment" (2004/09/06 - 2004/09/11) Other (Member of the Organising Committee)	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Event participation

	Activity description Type of event	Event name Institution / Organization
2022 - Current	Lecturer of the topic "Mechanisms of host resistance" (with Martin Hoenigl, Austria) Symposium	Fungal Sepsis Training Programme European Society of Intensive Care Medicine, Belgium Gilead Sciences, France
2014 - Current	From bench to bedside: how do we get there? Round table	Hematopoiesis: from Bench to Bedside Universidade do Minho Escola de Medicina, Portugal

Jury of academic degree

	Topic Role	Candidate name (Type of degree) Institution / Organization
2023	The role of carboxylic acids in the pathogenecity of Candida albicans (Thesis) Main arguer	Faezeh Ghasemi (Master) Universidade do Minho Escola de Ciencias, Portugal
2023	MCP-1 as a prognostic biomarker in hypersensitivity pneumonitis: a prospective study (Thesis) Main arguer	Ana Cristina Pinto (Master) Universidade do Porto Faculdade de Medicina, Portugal
2023	New generation antigen delivery system for Candida albicans recombinant proteins as a vaccination strategy against systemic fungal infections (Thesis) Main arguer	Augusto Barbosa (PhD) Universidade do Minho Escola de Ciencias, Portugal
2022	Fetal lung macrophage-derived secretome in the modulation of lung differentiation (Thesis) Arguer	Marcela da Silva Oliveira (Master) Universidade do Minho Escola de Medicina, Portugal
2022	Viral-associated pulmonary aspergillosis (VAPA) in the intensive care unit (Thesis) Main arguer	Lore Vanderbeke (PhD) Katholieke Universiteit Leuven Departement Microbiologie Immunologie en Transplantatie, Belgium
2022	Molecular mechanisms of melanin secretion by melanocytes and processing within keratinocytes (Thesis) Arguer	Liliana Bento-Lopes (PhD) Universidade Nova de Lisboa, Portugal
2021	HIV-infected patients undergoing antiretroviral therapy have persistently reduced numbers of natural killer cells with an altered phenotype (Thesis) Arguer	Pedro Peixoto (Master) Universidade do Minho Escola de Medicina, Portugal
2021	Exploring the role of astrocytes in the pathophysiology of multiple sclerosis (Thesis) Arguer	Sofia Neves (PhD) Universidade do Minho Escola de Medicina, Portugal
2021	HIF-1a-mediated regulation of antifungal immunity in chronic pulmonary obstructive disease Supervisor	Sara Ferreira (Master) Universidade do Minho Escola de Medicina, Portugal
2021	Development and application of multiplatform metabolomic pipelines for the study of infectious diseases (Thesis) Main arguer	Miguel Fernández García (PhD) Universidad CEU San Pablo, Spain
2021	Exploring novel predisposing factors for fungal infections (Thesis) Main arguer	Intan M. W. Dewi (PhD) Radboud Universiteit, Netherlands
2021	The impact of glycans as regulators of T cell-mediated immune response in gastrointestinal disorders (Thesis) Main arguer	Bruno Oliveira (Master) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020	Syphilis, excluding congenital, detected at Hospital de Braga between 2004-2007 and 2015-2018: a comparative study at different time intervals (Thesis) Arguer	Ana Oliveira (Master) Universidade do Minho Escola de Medicina, Portugal
2020	Evaluation of factors impacting the clinical outcome of patients with carbapenem-resistant Klebsiella infection (Thesis) Arguer	Ana Ferreira (Master) Universidade do Minho Escola de Medicina, Portugal
2020	Occurrence of healthcare-associated infections by Escherichia coli and extended-spectrum ß-lactamase or carbepenemase-producing Klebsiella spp. in integrated continued care units (Thesis) Arguer	Elisabete Machado (Master) Universidade do Minho Escola de Medicina, Portugal
2020	The yin and yang of host-pathogen interactions in tuberculosis (Thesis) Arguer	Jeremy Sousa (PhD) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020	Modulation of the host immune response to a human fungal pathogen using ß-glucan-functionalized nanoparticles (Thesis) Arguer	Tânia Lima (PhD) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019	The role of zinc in the modulation of the gut microbiota and the local and tumoral immune response (Thesis) Arguer	Bernardo Rodrigues (Master) Universidade do Minho Escola de Medicina, Portugal
2019	Sociodemographic and clinical variables in the risk of Buruli ulcer development: a systematic review and meta-analysis (Thesis) Arguer	João Fevereiro (Master) Universidade do Minho Escola de Medicina, Portugal
2019	Assembly of granulomas during mycobacterial infections in mice: cellular and molecular dynamics (Thesis) Arguer	Mariana Resende da Silva (PhD) Universidade do Minho Escola de Medicina, Portugal
2019	Molecular mechanisms of melanin transfer and processing by keratinocytes (Thesis) Arguer	Hugo Moreiras (PhD) Universidade Nova de Lisboa, Portugal
2019	Molecular sensors of codon ambiguity in Candida albicans signaling pathways (Thesis) Arguer	Joana Fraga (PhD) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018	Innate regulation of granulomatous inflammation in sarcoidosis Supervisor	Cláudia Campos (Master) Universidade do Minho Escola de Medicina, Portugal
2017	Antiphospholipid antibodies in an obstetric population (Thesis) Arguer	Daniela Barros (Master) Universidade do Minho Escola de Medicina, Portugal
2017	Functional and genetic analysis of sexual reproduction in the thermodimorphic fungal pathogen Paracoccidioides spp. (Thesis) Arguer	Jessica Gomes-Rezende (PhD) Universidade do Minho Escola de Medicina, Portugal
2017	Identification of human and pathogen molecular variants associated to tuberculosis heterogeneity (Thesis) Arguer	Helder Novais e Bastos (PhD) Universidade do Minho Escola de Medicina, Portugal
2016	Acute myeloid leukemia (AML): impact of metabolism and proteolytic systems on the prognosis/outcome of AML patients (Thesis) Arguer	Ana Raquel Afonso (Master) Universidade do Minho Escola de Medicina, Portugal
2016	The effects of arginine supplementation on a-synuclein-mediated toxicity - studies on yeast aging model (Thesis) Arguer	Maria de Fátima Carvalho (Master) Universidade do Minho Escola de Medicina, Portugal
2015	Development of a TNF-capturing device as therapeutics of inflammatory arthritic diseases (Thesis) Main arguer	Elisa Bacelo (Master) Universidade do Minho Escola de Engenharia, Portugal
2015	Comparative study of the opportunistic yeasts Candida glabrata and Candida bracarensis infection strategies (Thesis) Main arguer	Tânia Lima (Master) Universidade do Minho Escola de Ciencias, Portugal
2014	Impact of proteolytic systems and metabolism on the outcome of patients with acute myeloid leukemia (Thesis) Arguer	Pedro Barros (Master) Universidade do Minho Escola de Medicina, Portugal
2014	Evaluation of the diagnostic and prognostic utility of the plasma cell burden detected by bone marrow biopsy, bone marrow aspiration, and flow cytometry in multiple myeloma patients followed in Hospital de Braga (Thesis) Arguer	Miguel Gouveia (Master) Universidade do Minho Escola de Medicina, Portugal

Ad Hoc journal article review

	Journal title (ISSN)	Publisher
2024 - 2024	Journal of Leukocyte Biology (1938-3673)	Oxford Academic
2024 - 2024	International Journal of Infectious Diseases (1878-3511)	International Society for Infectious Diseases
2024 - 2024	Oxford Open Immunology (2633-6960)	Oxford University Press
2023 - 2024	Journal of Clinical Investigation (1558-8238)	American Society for Clinical Investigation
2017 - 2024	Nature Communications (2041-1723)	Springer Science and Business Media LLC
2016 - 2024	PLoS Pathogens (1553-7374)	Public Library of Science
2023 - 2023	Blood Cancer Journal (2044-5385)	Springer Nature
2023 - 2023	Trends in Immunology (1471-4981)	Cell Press
2023 - 2023	Immunology Letters (1879-0542)	Elsevier
2023 - 2023	Fungal Biology Reviews (1878-0253)	Elsevier
2022 - 2023	iScience (2589-0042)	Cell Press
2022 - 2023	Microbiology Spectrum (2165-0497)	American Society for Microbiology
2021 - 2023	mBio (2150-7511)	American Society for Microbiology
2020 - 2023	Infection and Immunity (1098-5522)	American Society for Microbiology
2019 - 2023	Nature Microbiology (2058-5276)	Springer Nature
2018 - 2023	Frontiers in Cellular and Infection Microbiology (2235-2988)	Frontiers Media SA
2013 - 2023	Mycopathologia (1573-0832)	Springer-Verlag
2022 - 2022	Parasite Immunology (1365-3024)	Wiley Online Library
2022 - 2022	Expert Review of Anti-Infective Therapy (1478-7210)	Taylor & Francis
2022 - 2022	Experimental Biology and Medicine (1535-3699)	SAGE Publishing
2022 - 2022	Journal of Clinical Immunology (0271-9142)	Springer Science+Business Media
2022 - 2022	Open Forum Infectious Diseases (2328-8957)	Oxford Academic
2022 - 2022	Cellular Immunology (0008-8749)	Elsevier
2022 - 2022	Virulence (2150-5594)	Taylor & Francis
2022 - 2022	Journal of Biological Chemistry (0021-9258)	American Society for Biochemistry and Molecular Biology
2022 - 2022	Applied Microbiology and Biotechnology (0175-7598)	Springer Nature
2017 - 2022	Frontiers in Immunology (1664-3224)	Frontiers Media SA
2011 - 2022	The Journal of Infectious Diseases (1537-6613)	Oxford University Press
2021 - 2021	BMC Pulmonary Medicine (1471-2466)	Springer Nature
2021 - 2021	Annals of Translational Medicine (2305-5839)	AME Publishing Company
2021 - 2021	Aging and Disease (2152-5250)	JKL International on behalf of the International Society on Aging and Disease
2021 - 2021	Transplant Infectious Diseases (1399-3062)	Wiley Online Library
2021 - 2021	BMC Infectious Diseases (1471-2334)	Springer Nature
2021 - 2021	Mediterranean Journal of Hematology and Infectious Diseases (2035-3006)	Mattioli 1885
2020 - 2021	Genome Medicine (1756-994x)	Springer Nature
2020 - 2021	Journal of Fungi (2309-608X)	MDPI AG
2019 - 2021	European Journal of Immunology (1521-4141)	Wiley (John Wiley & Sons)
2020 - 2020	Current Opinion in Immunology (0952-7915)	Elsevier
2020 - 2020	Cell Reports (2211-1247)	Elsevier
2020 - 2020	eLife (2050-084X)	eLife Sciences Publications, Ltd
2020 - 2020	Current Opinion in Microbiology (1369-5274)	Elsevier
2020 - 2020	Future Microbiology (1746-0921)	Future Medicine
2019 - 2019	Applied and Environmental Microbiology (1098-5336)	American Society for Microbiology
2018 - 2018	Pulmonology (2531-0437)	Elsevier
2018 - 2018	EBioMedicine (2352-3964)	Elsevier
2016 - 2016	Clinical Microbiology and Infection (1469-0691)	Elsevier
2013 - 2013	BioMed Research International (2314-6141)	Hindawi Limited

Association member

	Society Organization name	Role
2024 - Current	PLoS Pathogens	Academic Editor
2022 - Current	Microbiology Spectrum	Editorial Board Member
2022 - Current	Infection and Immunity	Editorial Board Member
2022 - Current	Frontiers in Fungal Biology	Specialty Chief Editor for Medical Mycology
2021 - Current	American Society for Microbiology	Member
2020 - Current	FEBS Advanced Lecture Course on Human Fungal Pathogens	Member of the Scientific Advisory Board
2020 - Current	Frontiers in Microbiology - section Infectious Diseases	Associate Editor
2019 - Current	Portuguese Society for Medical Mycology	Member of the Direction Board
2018 - Current	Working Group on Immunologic Markers for Diagnosis and Treatment Stratification of Invasive Mold Infection of the European Confederation of Medical Mycology	Co-chair
2018 - Current	Portuguese Society for Immunology	Member of the Direction Board
2017 - Current	Portuguese Society for Immunology	Member
2017 - Current	European Confederation of Medical Mycology	Fellow (nominated)
2016 - Current	Frontiers in Cellular and Infection Microbiology	Review Editor
2011 - Current	European Society of Clinical Microbiology and Infectious Diseases	Member
2007 - Current	Portuguese Society of Biochemistry	Member
2021 - 2022	Journal of Fungi	Guest Editor for the Special Issue "New Insights into Current Understanding of Host–Fungal Interactions"
2014 - 2022	The Journal of Infectious Diseases	Member of the Editorial Advisory Board
2020 - 2021	Journal of Fungi	Guest Editor for the Special Issue "Metabolic Regulation of the Host-Fungus Interaction"
2019 - 2020	Current Opinion in Microbiology	Guest Editor
2017 - 2020	Frontiers in Microbiology - section Fungi and Their Interactions	Associate Editor
2018 - 2019	Frontiers in Immunology	Guest Associate Editor

Committee member

	Activity description Role	Institution / Organization
2023 - Current	Direction of ICVS, University of Minho Director	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2023 - Current	Scientific Council of the School of Medicine, University of Minho Member	Universidade do Minho Escola de Medicina, Portugal
2022 - Current	Immunobiology of Inflammatory and Infectious Diseases Research Team - ICVS, University of Minho Coordinator	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2022 - Current	Coordinating Committee for the Evaluation of the Research Staff (CCA-PI-EM) Member	Universidade do Minho Escola de Medicina, Portugal
2021 - Current	School Council of the School of Medicine, University of Minho Member	Universidade do Minho Escola de Medicina, Portugal
2019 - Current	Direction Board of ICVS, University of Minho Member	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2014 - Current	Scientific Council of ICVS, University of Minho Member	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019 - 2023	Microbiology and Infection Research Domain - ICVS, University of Minho Coordinator	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2020 - 2021	Scientific Council for Life and Health Sciences (CCCVS) of the Fundação para a Ciência e a Tecnologia (FCT) Member	Fundação para a Ciência e Tecnologia (FCT), Portugal
2019 - 2019	Electoral Committee for the Direction of ICVS, University of Minho Member	Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2012 - 2014	Faculty of the PhD Programme in Systems Biology in Immune and Infectious Diseases, University of Perugia, Italy Member	Università degli Studi di Perugia Dipartimento di Medicina Sperimentale, Italy

Conference scientific committee

	Conference name	Conference host
2022 - 2022	33rd European Congress of Clinical Microbiology and Infectious Diseases	European Society of Clinical Microbiology and Infectious Diseases
2021 - 2021	32nd European Congress of Clinical Microbiology and Infectious Diseases	European Society of Clinical Microbiology and Infectious Diseases
2020 - 2020	31st European Congress of Clinical Microbiology and Infectious Diseases	European Society of Clinical Microbiology and Infectious Diseases
2019 - 2019	30th European Congress of Clinical Microbiology and Infectious Diseases	European Society of Clinical Microbiology and Infectious Diseases
2018 - 2018	29th European Congress of Clinical Microbiology and Infectious Diseases	European Society of Clinical Microbiology and Infectious Diseases

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2021 - Current	Academic Profile 2	Integrated MSc in Medicine (Mestrado integrado)	Universidade do Minho Escola de Medicina, Portugal
2020 - Current	Fundamentals in Medicine 2	Integrated MSc in Medicine (Mestrado integrado)	Universidade do Minho Escola de Medicina, Portugal
2020 - Current	Academic Profile 1	Integrated MSc in Medicine (Mestrado integrado)	Universidade do Minho Escola de Medicina, Portugal
2014 - Current	Fundamentals of Immunology and Infection	Fundamentals of Immunology and Infection (Pós-Graduação)	Universidade do Minho Escola de Medicina, Portugal
2019 - 2023	Pathogenesis of respiratory mould diseases	Medical Mycology Course (Postgraduate Certificate)	Institut Pasteur, France
2022 - 2022	Molecular Mechanisms of Disease	PhD in Health Sciences (Doutoramento)	Universidade de Coimbra Faculdade de Medicina, Portugal
2021 - 2021	Infection and Immunity	PhD in Molecular and Cell Biology (Doutoramento)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021 - 2021	Methods and Techniques of Research	PhD in Health Sciences (Curso de doutoramento (conclusão de unidades curriculares))	Universidade de Coimbra Faculdade de Medicina, Portugal
2021 - 2021	Human Immunopathology	Integrated MSc in Medicine (Mestrado integrado)	Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014 - 2021	Biopathology and Introduction to Therapeutics	Integrated MSc in Medicine (Mestrado integrado)	Universidade do Minho Escola de Medicina, Portugal
2015 - 2017	Molecular Mechanisms of Disease	PhD in Health Sciences (Doutoramento)	Universidade de Coimbra Faculdade de Medicina, Portugal
2013 - 2014	General Pathology	BSc in Obstetrics (Laurea)	Università degli Studi di Perugia Dipartimento di Medicina Sperimentale, Italy
2012 - 2013	Mechanisms of Antibacterial and Antiviral Immunity	BSc in Nursing (Laurea)	Università degli Studi di Perugia Dipartimento di Medicina Sperimentale, Italy
2011 - 2012	Molecules and Cells	Integrated MSc in Medicine (Mestrado integrado)	Universidade do Minho Escola de Medicina, Portugal
2010 - 2010	Polymorphisms in immune genes and susceptibility to infections in allogeneic stem cell transplantation	Dottorato in Biotecnologie nel Trapianto del Midollo Osseo (Dottorato di Ricerca)	Università degli Studi di Perugia Dipartimento di Medicina, Italy
2003 - 2007	Molecules and Cells	Integrated MSc in Medicine (Mestrado integrado)	Universidade do Minho Escola de Medicina, Portugal
2005 - 2006	Biochemistry and Biophysics	BSc in Nursing (Licenciatura)	Universidade do Minho Escola Superior de Enfermagem, Portugal
2003 - 2004	Introduction to the Medicine Degree	Integrated MSc in Medicine (Mestrado integrado)	Universidade do Minho Escola de Medicina, Portugal

Evaluation committee

Interview (newspaper / magazine)

	Activity description	Newspaper / Forum
2021	Interview for the Observador/BPI/Fundação 'la Caixa' initiative on the research project funded by the "la Caixa Foundation" and FCT	Observador

Interview (tv / radio show)

	Program	Topic
2018 - Current	UM I&D	Research project funded by the "la Caixa Foundation" and FCT
2022 - 2022	Podcast Interview for the Observador/BPI/Fundação 'la Caixa' initiative	Research project funded by the "la Caixa Foundation" and FCT
2020 - 2020	90 Segundos de Ciência	Paper by Gonçalves et al. published in Nature Communications
2018 - 2018	Mentes que Brilham	Research project funded by the "la Caixa Foundation" and FCT
2018 - 2018	Mentes que Brilham	Paper by Stappers et al. published in Nature
2018 - 2018	3 às 10	Research project funded by the "la Caixa Foundation" and FCT
2018 - 2018	UM I&D	Research project funded by the "la Caixa Foundation" and FCT

Journal scientific committee

	Journal title (ISSN)	Publisher
2017 - 2022	Frontiers in Microbiology (1664-302X)	Frontiers Media SA
2019 - 2021	Expert Review of Clinical Immunology (1744-8409)	Informa UK (Taylor & Francis)
2019 - 2021	Microbial Pathogenesis (1096-1208)	Elsevier
2012 - 2021	Mycoses (1439-0507)	Wiley (Blackwell Publishing)
2012 - 2021	Medical Mycology (1460-2709)	Oxford University Press
2020 - 2020	Journal of Investigative Medicine (1708-8267)	BMJ
2020 - 2020	Frontiers in Genetics (1664-8021)	Frontiers Media SA
2019 - 2020	Cytotherapy (1477-2566)	Elsevier
2019 - 2020	Medical Microbiology and Immunology (1432-1831)	Springer-Verlag
2019 - 2019	American Journal of Tropical Medicine and Hygiene (1476-1645)	American Society of Tropical Medicine and Hygiene
2019 - 2019	Journal of Immunology Research (2314-7156)	Hindawi Limited
2018 - 2019	BMC Microbiology (1471-2180)	Springer (Biomed Central Ltd.)
2012 - 2019	Vaccine (0264-410X)	Elsevier
2018 - 2018	Folia Microbiologica (1874-9356)	Springer-Verlag
2018 - 2018	Scientific Reports (2045-2322)	Springer Science and Business Media LLC
2016 - 2018	Journal of Innate Immunity (1662-8128)	S. Karger AG
2017 - 2017	International Journal of Immunogenetics (1744-313X)	Wiley (Blackwell Publishing)
2017 - 2017	Pediatric Pulmonology (1099-0496)	Wiley (John Wiley & Sons)
2017 - 2017	Journal of Allergy and Clinical Immunology (0091-6749)	Elsevier
2017 - 2017	Beneficial Microbes (1876-2891)	Wageningen Academic Publishers
2017 - 2017	Journal of Visualized Experiments (1940-087X)	MyJoVE Corporation
2013 - 2017	PLoS ONE (1932-6203)	Public Library of Science
2016 - 2016	Journal de Mycologie Médicale (1156-5233)	Elsevier
2015 - 2015	Clinical Infectious Diseases (1537-6591)	Oxford University Press
2009 - 2015	Human Immunology (0198-8859)	Elsevier
2014 - 2014	Journal of Antimicrobial Chemotherapy (1460-2091)	Oxford University Press
2013 - 2013	International Scholarly Research Notices (2356-7872)	Hindawi Limited
2013 - 2013	Critical Care (1875-7081)	Springer (Biomed Central Ltd.)
2013 - 2013	Current Eye Research (1460-2202)	Informa UK (Informa Healthcare)
2013 - 2013	American Journal of Obstetrics and Gynecology (0002-9378)	Elsevier
2013 - 2013	Mediators of Inflammation (1466-1861)	Hindawi Limited
2012 - 2012	Brazilian Journal of Infectious Diseases (1678-4391)	SciELO
2012 - 2012	BMC Medical Genetics (1471-2350)	Springer (Biomed Central Ltd.)
2012 - 2012	Current Genomics (1389-2029)	Bentham Science
2009 - 2012	Clinical and Vaccine Immunology (1556-679X)	American Society for Microbiology
2011 - 2011	Memórias do Instituto Oswaldo Cruz (0074-0276)	SciELO
2011 - 2011	Clinical and Developmental Immunology (1740-2530)	Hindawi Limited
2011 - 2011	Immunological Investigations (1532-4311)	Informa UK (Taylor & Francis)
2011 - 2011	The Lancet Infectious Diseases (1473-3099)	Elsevier
2011 - 2011	Current Medicinal Chemistry - Anti-Infective Agents (1568-0126)	Bentham Science
2010 - 2011	Bone Marrow Transplantation (0268-3369)	Springer Nature
2010 - 2010	Journal of Invasive Fungal Infections	Remedica
2009 - 2009	Antimicrobial Agents and Chemotherapy (1098-6596)	American Society for Microbiology

Distinctions

Award

2023	SPI Best Paper Award Sociedade Portuguesa de Imunologia, Portugal
2019	Professor Manuel Teixeira da Silva Award Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2017	HPF2017 Award at the HFP2017 Advanced Lecture Course “Molecular Mechanisms of Host-Pathogens Interactions and Virulence in Human Fungal Pathogens” Journal of Fungi, Switzerland
2016	Prémio Robalo Cordeiro SPP/Novartis 2016 Sociedade Portuguesa de Pneumologia, Portugal
2015	ICVS Incentive to Research Award 2015 Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2012	ESID 2012 Award at the 15th Biennial Meeting of the European Society for Immunodeficiencies European Society for Immunodeficiencies, Netherlands
2011	Young Investigator Award at the 4th FEBS Advanced Lecture Course “Human Fungal Pathogens: Molecular Mechanisms of Host-Pathogen Interactions and Virulence” Federation of European Biochemical Societies, United Kingdom
2011	Jon J van Rood Award European Group for Blood and Marrow Transplantation Leiden, Netherlands
2007	Young Investigator Award at the 2nd FEBS Advanced Lecture Course “Human Fungal Pathogens: Molecular Mechanisms of Host-Pathogen Interactions and Virulence” Federation of European Biochemical Societies, United Kingdom

Title

2013	National Scientific Habilitation (Assistant Professor, sector 06/A3 - Microbiology) Ministero dell'Istruzione dell'Università e della Ricerca, Italy

Other distinction

2011	Meeting Grant of the Federation of European Microbiological Societies Federation Of European Microbiological Societies, Netherlands
2007	Meeting Grant of the Federation of European Microbiological Societies Federation Of European Microbiological Societies, United Kingdom

	Activity description Role	Institution / Organization	Funding entity
2023 - 2023	Wilhelm Sander Foundation Evaluator	Wilhelm Sander-Stiftung, Germany	Wilhelm Sander-Stiftung
2023 - 2023	Programma per Giovani Ricercatori 'Rita Levi Montalcini' Evaluator	Ministero dell'Istruzione dell'Università e della Ricerca, Italy	Ministero dell'Istruzione dell'Università e della Ricerca
2021 - 2023	Marie Sklodowska-Curie Postdoctoral Fellowships (PF) Life Sciences (LIF) Evaluator	European Commission, Belgium	European Commission
2022 - 2022	European Research Council Starting Grants Evaluator	European Commission, Belgium	European Commission
2021 - 2021	Doctoral Grants Evaluator	Fundo Regional para a Ciência e Tecnologia, Portugal	Fundo Regional para a Ciência e Tecnologia
2021 - 2021	Horizon Europe Cluster 1 Health Calls Evaluator	European Commission, Belgium	European Commission
2020 - 2021	The Paris Region Fellowship Programme Evaluator	EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions, Belgium	EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
2018 - 2021	ESCMID Research Grants Evaluator	European Society of Clinical Microbiology and Infectious Diseases, Switzerland	European Society of Clinical Microbiology and Infectious Diseases
2016 - 2021	Progetti di Ricerca di Interesse Nazionale - PRIN Evaluator	Ministero dell'Istruzione dell'Università e della Ricerca, Italy	Ministero dell'Istruzione dell'Università e della Ricerca
2020 - 2020	Personal Research Grants Evaluator	Israel Science Foundation, Israel	Israel Science Foundation
2020 - 2020	Early Career Fellowships - DBT/Wellcome Trust India Alliance Evaluator	Wellcome Trust DBT India Alliance, India	Wellcome Trust DBT India Alliance
2020 - 2020	Medicina Clínica e Ciências da Saúde Panel - FCT Bolsas BD 2020 Evaluator	Fundação para a Ciência e Tecnologia (FCT), Portugal	Fundação para a Ciência e Tecnologia (FCT)
2017 - 2020	Marie Sklodowska-Curie Individual Fellowships (MSCA-IF) Life Sciences (LIF) Evaluator	EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions, Belgium	EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
2019 - 2019	Medicina Clínica e Ciências da Saúde Panel - FCT Bolsas BD 2019 Evaluator	Fundação para a Ciência e Tecnologia (FCT), Portugal	Fundação para a Ciência e Tecnologia (FCT)
2019 - 2019	The LEaDing Fellows Postdocs Programme Evaluator	EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions, Belgium	EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
2019 - 2019	Generic Call for Proposals Evaluator	Agence nationale de la recherche, France	Agence nationale de la recherche
2018 - 2018	Interventi di Sostegno alla Ricerca Evaluator	Regione Autonoma della Sardegna, Italy	Regione Autonoma della Sardegna
2017 - 2017	Framework per l'Attrazione e il Rafforzamento delle Eccelenze per la Ricerca in Italia (FARE) Evaluator	Ministero dell'Istruzione dell'Università e della Ricerca, Italy	Ministero dell'Istruzione dell'Università e della Ricerca
2016 - 2016	SRLF Research Fellowships Evaluator	Société de Réanimation de Langue Française, France	Société de Réanimation de Langue Française
2015 - 2015	Biologia Experimental e Bioquímica Panel - FCT Bolsas BD 2015 Evaluator	Fundação para a Ciência e Tecnologia (FCT), Portugal	Fundação para a Ciência e Tecnologia (FCT)