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Birte Blankenhaus completed the Master in Biology in 2007/01/31 at the Universität Hamburg and successfully finished the Doktor (PhD) in Biology in 2011/11/25 at the Universität Hamburg. She is currently a Postdoc in the Immune regulation Lab of Prof. Marc Veldhoen at the Instituto de Medicina Molecular in Lisbon/Portugal. Birte published 12 articles in internationally peer reviewed journals and organized 2 event(s). She participated in 6 event(s), giving short talks and poster presentations. She is currently co-supervising 1 PhD thesis and supervises 1 MSc dissertation and co-supervised 1 MSc dissertation. Birte contributed to the success of 2 projects, one as Postdoc (with working contract; EC ERA chair) and one as Postdoctoral Fellow (ERC Advanced Grant). Birte has a broad expertise in the area of Medical and Health Sciences with emphasis in the field of Immunology, Infectious Diseases, Immune regulation and Signal transduction.
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Identification

Personal identification

Full name
Birte Blankenhaus

Citation names

  • Blankenhaus, Birte

Author identifiers

Ciência ID
FD19-D7A4-E29D
ORCID iD
0000-0003-0987-5228

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Immunology
  • Medical and Health Sciences - Health Sciences - Infectious Diseases

Languages

Language Speaking Reading Writing Listening Peer-review
German Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Portuguese Upper intermediate (B2) Upper intermediate (B2) Intermediate (B1) Upper intermediate (B2)
Education
Degree Classification
2011/11/25
Concluded
 Biology (Doktor (PhD))
Universität Hamburg, Germany
"”Investigation of Strongyloides ratti infection in mice: The role of regulatory T cells (Treg) and regulatory receptors during infection" (THESIS/DISSERTATION)
 Magna cum laude
2007/01/31
Concluded
 Biology (Master)
Major in Biochemie
Universität Hamburg, Germany
Affiliation

Science

Category
Host institution 		Employer
2017/04/01 - 2020/12/31 Postdoc (Research) Instituto de Medicina Molecular, Portugal
2012/08/01 - 2017/03/31 Postdoc (Research) Instituto Gulbenkian de Ciência, Portugal
2011/12/01 - 2012/06/01 Postdoc (Research) Bernhard-Nocht-Institut für Tropenmedizin, Germany

Others

Category
Host institution 		Employer
2008/02/01 - 2011/11/30 PhD student Bernhard-Nocht-Institut für Tropenmedizin, Germany
Projects

Grant

Designation Funders
2012/08/01 - 2017/03/31 Tissue Damage Control Regulates The Pathogenesis of Immune Mediated Inflammatory Diseases
info:eu-repo/grantAgreement/EC/FP7/294709/EU
Post-doc Fellow
European Commission
Concluded

Contract

Designation Funders
2015/07/01 - 2020/06/30 EXCELLtoINNOV
667824
Post-doc
Instituto de Medicina Molecular, Portugal
 European Commission
Ongoing
Outputs

Publications

Journal article
  1. Ferreira, Cristina; Barros, Leandro; Baptista, Marta; Blankenhaus, Birte; Barros, André; Figueiredo-Campos P; Konjar, Š.; et al. "Type 1 TREG cells promote the generation of CD8+ tissue resident memory T cells.". Nature Immunology (2020): https://www.nature.com/articles/s41590-020-0674-9.
    Published
  2. Blankenhaus B; Braza F; Martins R; Bastos-Amador P; González-García I; Carlos AR; Mahu I; et al. "Ferritin regulates organismal energy balance and thermogenesis.". Molecular Metabolism (2019): http://europepmc.org/abstract/med/30954544.
    10.1016/j.molmet.2019.03.008
  3. Ramos S; Carlos AR; Sundaram B; Jeney V; Ribeiro A; Gozzelino R; Bank C; et al. "Renal control of disease tolerance to malaria.". Proceedings of the National Academy of Sciences of the United States of America (2019): http://europepmc.org/abstract/med/30833408.
    10.1073/pnas.1822024116
  4. Figueiredo-Campos P; Ferreira C; Blankenhaus B; Veldhoen M. "Eimeria vermiformis Infection Model of Murine Small Intestine.". Bio-protocol (2018): http://europepmc.org/abstract/med/31032380.
    10.21769/BioProtoc.3122
  5. Veldhoen M; Blankenhaus B; Konjar Š; Ferreira C. "Metabolic wiring of murine T cell and intraepithelial lymphocyte maintenance and activation.". European journal of immunology (2018): http://europepmc.org/abstract/med/30043974.
    10.1002/eji.201646745
  6. Konjar Š; Frising UC; Ferreira C; Hinterleitner R; Mayassi T; Zhang Q; Blankenhaus B; et al. "Mitochondria maintain controlled activation state of epithelial-resident T lymphocytes.". Science immunology (2018): http://europepmc.org/abstract/med/29934344.
    10.1126/sciimmunol.aan2543
  7. Konjar, Š.; Ferreira, C.; Blankenhaus, B.; Veldhoen, M.. "Intestinal barrier interactions with specialized CD8 T cells". Frontiers in Immunology 8 OCT (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85032198292&partnerID=MN8TOARS.
    10.3389/fimmu.2017.01281
  8. Weis, S.; Carlos, A.R.; Moita, M.R.; Singh, S.; Blankenhaus, B.; Cardoso, S.; Larsen, R.; et al. "Metabolic Adaptation Establishes Disease Tolerance to Sepsis". Cell 169 7 (2017): 1263-1275.e14. http://www.scopus.com/inward/record.url?eid=2-s2.0-85020812716&partnerID=MN8TOARS.
    10.1016/j.cell.2017.05.031
  9. Breloer, M.; Hartmann, W.; Blankenhaus, B.; Eschbach, M.-L.; Pfeffer, K.; Jacobs, T.. "Cutting edge: The BTLA-HVEM regulatory pathway interferes with protective immunity to intestinal helminth infection". Journal of Immunology 194 4 (2015): 1413-1416. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922572269&partnerID=MN8TOARS.
    10.4049/jimmunol.1402510
  10. Blankenhaus, B.; Reitz, M.; Brenz, Y.; Eschbach, M.-L.; Hartmann, W.; Haben, I.; Sparwasser, T.; et al. "Foxp3+ Regulatory T Cells Delay Expulsion of Intestinal Nematodes by Suppression of IL-9-Driven Mast Cell Activation in BALB/c but Not in C57BL/6 Mice". PLoS Pathogens 10 2 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84895738894&partnerID=MN8TOARS.
    10.1371/journal.ppat.1003913
  11. Blankenhaus, B.; Klemm, U.; Eschbach, M.-L.; Sparwasser, T.; Huehn, J.; Kühl, A.A.; Loddenkemper, C.; Jacobs, T.; Breloer, M.. "Strongyloides ratti infection induces expansion of foxp3 + regulatory T cells that interfere with immune response and parasite clearance in BALB/c Mice". Journal of Immunology 186 7 (2011): 4295-4305. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955040264&partnerID=MN8TOARS.
    10.4049/jimmunol.1001920
  12. Eschbach, M.-L.; Klemm, U.; Kolbaum, J.; Blankenhaus, B.; Brattig, N.; Breloer, M.. "Strongyloides ratti infection induces transient nematode-specific Th2 response and reciprocal suppression of IFN-¿ production in mice". Parasite Immunology 32 5 (2010): 370-383. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950649421&partnerID=MN8TOARS.
    10.1111/j.1365-3024.2010.01199.x
Activities

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2018/01/01 - 2021/12/31 How to activate non-conventional Epithelial T cells
Co-supervisor
Instituto de Medicina Molecular, Portugal
2019/09/01 - 2020/09/30 The role of phosphatases during the activation of intraepithelial lymphocytes
Supervisor
Universidade de Coimbra, Portugal
2016/09/01 - 2017/10/30 Macrophages control tissue homeostasis via Ferritin heavy chain
Co-supervisor
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2015/05/01 - 2015/11/06 2nd Annual Joint Postdoctoral Meeting Participating Institutions: Instituto Gulbenkian de Ciencia (IGC), Instituto de Medicina Molecular (IMM), Instituto de Tecnologia Quimica e Biologia (ITQB), Instituto de Biologia Experimental e Tecnologica (iBET) e Champalimaud Foundation Hotel do Sado, Setúbal, Portugal (2015/11/04 - 2015/11/06)
Meeting (Member of the Organising Committee)
 Instituto Gulbenkian de Ciência, Portugal
2012/11/01 - 2013/10/31 Organization of the biweekly Host-Microbe-Immunology Meeting between the Instituto Gulbenkian de Ciencia (Oeiras, Portugal) and the Instituto de Medicina Molecular (Lisbon, Portugal) (2012/11/01)
Seminar (Member of the Organising Committee)
 Instituto Gulbenkian de Ciência, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2019/10/08 - 2019/10/10 Tissue immunity in Health and Disease
Symposium
 Tissue immunity in Health and Disease
Centro Champalimaud, Portugal
2019/03/20 - 2019/03/22 Tissue Clearing Workshop 2019
Workshop
 Tissue Clearing Workshop
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2015/09/30 - 2015/10/03 Participation in Conference: TOLL 2015, Targeting Innate Immunity
Conference
 TOLL 2015, Targeting Innate Immunity
Instituto Gulbenkian de Ciência, Portugal
2012/11/25 - 2012/11/27 Oral presentation: Title: Different impact of regulatory T cells on nematode-induced immune evasion in BALB/c and C57BL/6 mice
Meeting
 Annual meeting of the Sociedade Portuguesa de Imunologia, Porto, 2012
Universidade do Porto, Portugal
2010/03/16 - 2010/03/20 Oral presentation: Title: The role of regulatory receptors during the murine Strongyloides ratti infection
Conference
 Annual meeting of the German Society for Parasitology, Düsseldorf, Germany, 2010
Heinrich Heine Universität Düsseldorf Mathematisch-Naturwissenschaftliche Fakultät, Germany
2010 - 2010 Oral presentation: Title: Strongyloides ratti infection induces expansion of Foxp3+ regulatory T cells that interfere with immune response and parasite clearance in BALB/c mice
Meeting
 Annual meeting of the Northern German Immunologists, Research Center Borstel, Germany, 2010
Forschungszentrum Borstel Leibniz-Zentrum für Medizin und Biowissenschaften, Germany

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2019/11/18 A protective role for ataxia-telangiectasia mutated in hemolytic conditions
(Thesis) Main arguer
 Susana Gomes Rodrigues Martins (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/10/17 New insights into interferon-mediated immune responses elicited by Plasmodium liver stage infection Unravelling the role of Viperin induction
(Thesis) Main arguer
 Diana Alves Moita (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Association member

Society Organization name Role
2012/09/01 - Current Sociedade Portuguesa de Imunologia
2008/01/01 - Current Deutsche Gesellschaft für Immunologie /German Society for Immunology

Committee member

Activity description
Role 		Institution / Organization
2014/10/15 - 2015/11/30 Member of the Postdoctoral Committee in the Instituto Gulbenkian de Ciencia
Member
 Instituto Gulbenkian de Ciência, Portugal