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I have a degree in Biochemistry from the Universidade de Évora. I concluded a Master's thesis entitled “Validation of Potential Proteomic Biomarkers in Obstructive Sleep Apnea Syndrome” under the Master's program in Biologia Humana e Ambiente, Faculdade de Ciências, Universidade de Lisboa. My thesis work was carried out at the Laboratório de Proteómica, Departamento de Genética Humana, INSA, Lisboa. To continue this study, I obtained a PhD fellowship at FCT, and during my research I published the results in an article as first author, won a prize for best poster at an international congress and participated in various national and international courses and conferences. I am currently in the final stages of completing my PhD in Biologia - specialization in Biologia Molecular, Faculdade de Ciências, Universidade de Lisboa. I feel that along the way I have acquired professional skills, responsibility and scientific maturity.
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Identification

Personal identification

Full name
Cristina Valentim Coelho

Citation names

  • Valentim-Coelho, Cristina
  • Cristina Valentim-Coelho
  • Coelho, Cristina

Author identifiers

Ciência ID
FD16-2D05-23E5

Email addresses

  • cristina.valentim@insa.saude-min.pt (Professional)
  • cris.coelho15@gmail.com (Personal)

Addresses

  • Instituto Nacional de Saúde Doutor Ricardo Jorge, Lab. Proteómica, Departamento de Genética Humana, 1649-016, Avenida Padre Cruz, Lisboa, Lisboa, Portugal (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry
  • Natural sciences - Biological Sciences - Biochemical Research Methods
  • Natural sciences - Biological Sciences - Biology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Medical and Health Sciences
  • Medical and Health Sciences - Basic Medicine - Toxicology
  • Medical and Health Sciences - Health Sciences - Public and Environmental Health

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Spanish; Castilian Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2)
Education
Degree Classification
2024
Ongoing
 Biologia (Doutoramento)
Major in Especialidade: Biologia Molecular
Universidade de Lisboa Faculdade de Ciências, Portugal
""Proteome Profiling in Obstructive Sleep Apnea Severity and Treatment Response Towards Early Diagnosis and Prognosis Prediction" " (THESIS/DISSERTATION)
2020/09/30 - 2020/10/02
Concluded
 XI Hands-on Course in Ultrafast Sample Treatment for Proteomics (Outros)
Major in Proteómica
Universidade Nova de Lisboa, Portugal
2019/11/04 - 2019/11/07
Concluded
 Course - Integrative Biological Interpretation using Proteomics (IBIP) (Outros)
Major in Gulbenkian Training Programme in Bioinformatics
Instituto Gulbenkian de Ciência, Portugal
2019/04/01 - 2019/04/05
Concluded
 Course - Proteomics Data Analysis (PDA) (Outros)
Major in Gulbenkian Training Programme in Bioinformatics
Instituto Gulbenkian de Ciência, Portugal
2016/05/31 - 2016/06/03
Concluded
 Hands-on Course Bioinformatics tools in Clinical Proteomics Data Analysis (Outros)
Major in Bioinformatics in Clinical Proteomics
Universidade de Lisboa Faculdade de Ciências, Portugal
2013/09 - 2015/12/09
Concluded
 Biologia Humana e Ambiente (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Validação de Potenciais Biomarcadores Proteómicos na Síndrome da Apneia Obstrutiva do Sono" (THESIS/DISSERTATION)
 17/20
2008/10 - 2012/09/12
Concluded
 Bioquímica (Licenciatura)
Universidade de Évora Escola de Ciências e Tecnologia, Portugal
"Remoção de Paracetamol com materiais de carbono" (THESIS/DISSERTATION)
 13/20
Affiliation

Science

Category
Host institution 		Employer
2016/01/01 - 2016/07/31 Research Trainee (Research) Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal
Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal
2014/09/01 - 2015/12/31 Research Trainee (Research) Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal
Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal

Others

Category
Host institution 		Employer
2018/01/01 - Current PhD Student supervised by Doctor Deborah Penque (SFRH/BD/133511/2017) Fundação para a Ciência e a Tecnologia, Portugal
Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal
Projects

Grant

Designation Funders
2018/01/01 - 2024 "Proteome Profiling in Obstructive Sleep Apnea Severity and Treatment Response Towards Early Diagnosis and Prognosis Prediction"
SFRH/BD/133511/2017
PhD Student Fellow
Universidade de Lisboa Faculdade de Ciências, Portugal

Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Conference paper
  1. Vaz, Fátima; Valentim-Coelho, Cristina; Neves, Sofia; Pinto, Paula; Bárbara, Cristina; Penque, Deborah. "Diabetes mellitus tipo 2 (DMT2) associada a Sindrome de Apneia Obstrutiva do Sono (SAOS): um estudo proteómico". Paper presented in 15.º Congresso Português de Diabetes, Vilamoura, 2019.
Conference poster
  1. Cristina Valentim-Coelho. "Shotgun proteomics approach to better understand the regulation of red blood cells homeostasis in obstructive sleep apnea patients under effect of positive airway pressure (PAP) treatment". Paper presented in 8th International Caparica Conference on Analytical Proteomics (ICAP), 2022.
  2. Joana Saraiva; Cristina Valentim-Coelho; Fátima Vaz; Antunes, Marilia; Neves, Sofia; Ricardo Peliano; Odilia Andrade. "COVID-19 Vaccination: A study on red blood cells and their impact in the immune system by omics-based approaches". Paper presented in 8th Internacional Caparica Conference on Analytical Proteomics (ICAP), 2022.
  3. Cristina Valentim-Coelho. "Shotgun Proteomics of Red Blood Cells from Obstructive Sleep Apnea patients under Positive Airway Pressure Treatment". Paper presented in ProteoVilamoura, 2022.
  4. Joana Saraiva; Cristina Valentim-Coelho; Fátima Vaz; Antunes, Marilia; Ricardo Peliano; Odilia Andrade. "Investigating the impact of COVID-19 vaccines on the red blood cell immune function by omics-based approaches". Paper presented in ProteoVilamoura, 2022.
  5. Cristina Valentim-Coelho; Fátima Vaz; Inês L. Martins; Amélia Feliciano; Paula Pinto; Cristina Bárbara; Deborah Penque. "Obstructive Sleep Apnea: a proteomics study of the effects of positive airway pressure therapy". Paper presented in 6th ICAP - 6th International Congress on Analytical Proteomics, 2019.
  6. Cristina Valentim-Coelho; Fátima Vaz; Amélia Feliciano; Paula Pinto; Cristina Bárbara; Deborah Penque. "Effects of Positive Airway Pressure Therapy on Red Blood Cells in Patients with Obstructive Sleep Apnea". Paper presented in IV NOVAhealth Genetics Workshop, 2019.
  7. Vaz, Fátima; Valentim-Coelho, Cristina; Neves, Sofia; Feliciano, Amélia; Pinto, Paula; Cristina, Bárbara; Penque, Deborah. "Proteomics of Obstructive Sleep Apnea with type 2 Diabetes Mellitus". Paper presented in IV NOVAhealth Genetics Workshop, 2019.
  8. Cristina Valentim-Coelho; Fátima Vaz; Amélia Feliciano; Paula Pinto; Cristina Bárbara; Deborah Penque. "Effects of Positive Airway Pressure Therapy on Red Blood Cell Proteome from Patients with Obstructive Sleep Apnea". Paper presented in XIII Annual Congress of the European Proteomics Association (EUPA): From Genes via Proteins and their Interactions to Functions, 2019.
  9. Cristina Valentim-Coelho; Fátima Vaz; Amélia Feliciano; Paula Pinto; Cristina Bárbara; Deborah Penque. "Proteomic effects of PAP therapy on red blood cells in males with Obstructive Sleep Apnea". Paper presented in XII European Proteomics Association (EUPA) Congress, 2018.
  10. Fátima Vaz; Amélia Feliciano; Cristina Valentim-Coelho; Vukosava Milic Torres; Atul Malhotra; Paula Pinto; Cristina Bárbara; Deborah Penque. "Obstructive Sleep Apnea: New insights into antioxidant activity and cellular response to stress". Paper presented in 2nd ISPROF - International Symposium on Profiling - Bioscope Group in collaboration with FCT - UNL, 2015.
Journal article
  1. Valentim-Coelho, Cristina; Vaz, Fátima; Antunes, Marília; Neves, Sofia; Martins, Inês L.; Osório, Hugo; Feliciano, Amélia; et al. "Redox–Oligomeric State of Peroxiredoxin-2 and Glyceraldehyde-3-Phosphate Dehydrogenase in Obstructive Sleep Apnea Red Blood Cells under Positive Airway Pressure Therapy". Antioxidants 9 12 (2020): 1184. http://dx.doi.org/10.3390/antiox9121184.
    Open access • Published • 10.3390/antiox9121184
  2. Feliciano, Amélia; Vaz, Fátima; Valentim-Coelho, Cristina; Torres, Vukosava M.; Silva, Rita; Prosinecki, Vesna; Alexandre, Bruno M.; et al. "Evening and morning alterations in Obstructive Sleep Apnea red blood cell proteome". Data in Brief 11 (2017): 103-110. http://dx.doi.org/10.1016/j.dib.2017.01.005.
    Published • 10.1016/j.dib.2017.01.005
  3. Feliciano, Amélia; Vaz, Fátima; Torres, Vukosava M; Valentim-Coelho, Cristina; Silva, Rita; Prosinecki, Vesna; Alexandre, Bruno M; et al. "Evening and morning peroxiredoxin-2 redox/oligomeric state changes in obstructive sleep apnea red blood cells: Correlation with polysomnographic and metabolic parameters". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1863 2 (2017): 621-629. http://dx.doi.org/10.1016/j.bbadis.2016.11.019.
    Published • 10.1016/j.bbadis.2016.11.019
Thesis / Dissertation
  1. Coelho, Cristina. "Validação de Potenciais Biomarcadores Proteómicos na Síndrome da Apneia Obstrutiva do Sono". Master, Universidade de Lisboa Faculdade de Ciências, 2015. http://hdl.handle.net/10451/22497.
  2. Coelho, Cristina. "Remoção de Paracetamol com Materiais de Carbono". Degree, Universidade de Évora Escola de Ciências e Tecnologia, 2012.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/11/08 Shotgun Proteomics evaluation of Obstructive Sleep Apnea (OSA) severity and response to Positive Airway Pressure (PAP) treatment 3º Dia do Jovem Investigador
Instituto Nacional de Saúde Doutor Ricardo Jorge (Lisboa, Portugal)
2019/07/10 Obstructive Sleep Apnea: a proteomics study of the effects of positive airway pressure therapy VI International Caparica Conference on Analytical Proteomics (ICAP)
PROTEOMASS Scientific Society (Costa da Caparica, Portugal)

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2022/07/18 - 2022/07/21 At the Internacional Caparica Conference on Analytical Proteomics (ICAP) I presented an abstract as a poster presenter about my PhD work "Shotgun proteomics approach to better understand the regulation of red blood cells homeostasis in obstructive sleep apnea patients under effect of positive airway pressure (PAP) treatment", Poster nº 12
Conference
 8th Internacional Caparica Conference on Analytical Proteomics (ICAP)
Associação Científica Proteomass, Portugal
2022/05/11 - 2022/05/13 At the ProteoVilamoura I presented an abstract as a poster presenter about my PhD work "Shotgun Proteomics of Red Blood Cells from Obstructive Sleep Apnea patients under Positive Airway Pressure Treatment".
Congress
 ProteoVilamoura
2020/10/12 - 2020/10/16 The Human Proteome Organization (HUPO) is an international scientific organization represents and promotes proteomics through international cooperation and collaborations by promoting the development of new technologies, techniques and training.
Congress
 19th Human Proteome Organization World Congress - Pre-Congress Training
Human Proteome Organisation, Canada
2019/03/24 - 2019/03/28 At the European Proteomics Association (EUPA), I presented an abstract as a poster presenter about my PhD work "Effects of positive airway pressure therapy on red blood cell proteome from patients with obstructive sleep apnea", Poster nº 261
Congress
 Proteomic Forum 2019 - XIII Annual Congress of the European Proteomics Association: From Genes via Proteins and their Interactions to Functions
European Proteomics Association (EUPA), Germany
2018/06/16 - 2018/06/20 The European Proteomics Association (EUPA) prepared an interesting program, which combined a variety of events, several of which were specially dedicated to young researchers. For this congress I presented an abstract as a poster presenter about my PhD work "Proteomic effects of PAP therapy on red blood cells in with obstructive sleep apnea", Poster nº 100
Congress
 XII European Proteomics Association (EUPA) Congress – Translating genomes into biological functions
European Proteomics Association (EUPA), Spain

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2019/02/02 - 2019/02/28 Clinic Proteomics Medicina (Doutoramento) Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal

Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2018/04/04 - 2018/04/07 Clinic Proteomics Medicina (Doutoramento) Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal

Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Distinctions

Award

2022 Excellent Poster Presentation Prize
Associação Científica Proteomass, Portugal

Other distinction

2019 European Cooperation for Science and Technology (eCOST) Grant - COST Action CA16113 CliniMARK: "good biomarker practice" to increase the number of clinically validated biomarkers
European Cooperation for Science and Technology - eCOST (Programme Horizon 2020), Belgium
2018 European Cooperation for Science and Technology (eCOST) Grant - COST Action CA16113 CliniMARK: "good biomarker practice" to increase the number of clinically validated biomarkers
European Cooperation in Science and Technology - eCOST (Programme Horizon 2020), Belgium
2018 PhD fellowship - SFRH/BD/133511/2017
Fundação para a Ciência e a Tecnologia, Portugal