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Filipe Miguel Pinto Morais has finalized, in 2017, his BSc degree in Biochemistry with an exciting project entitled "New cationic benzoporphyrins: synthesis and antimicrobial activity" with a final degree grade of 15/20. In 2019, his concluded his master's degree with a final grade of 17/20, both obtained at the University of Aveiro. During his master's degree, which was developed in collaboration with the Departamento de Fisiologia e Cirurgica Cardiotoráxica from Faculdade Medicina Universidade Porto his acquired substantial knowledge in the pathological mechanisms underlying non-communicable diseases. It allowed him to purchase other technical skills in the use of several methodologies, mainly in the field of proteomics, to study a biomedical issue. With the MSc thesis entitled "Effect of exercise training on right ventricular remodeling induced by pulmonary arterial hypertension", He's achieved the final classification of 18/20. Actually, He is autor of 1 original research paper and co-author of 1 original research paper in an international peer-reviewed journal, 1 proceeding, 9 posters and 2 oral communications in national and international scientific conferences. 1 of the poster communications was highlighted with the best poster award in an international meeting. Currently, He's a research fellowship in the scope of PORP2PS project at the University of Aveiro with the aim to develop new derivatives based on the conjugation of easily accessible porphyrin scaffolds with triphenylphosphonium salts.
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Identification

Personal identification

Full name
Filipe Miguel Pinto Morais

Citation names

  • Morais, Filipe

Author identifiers

Ciência ID
FB18-9732-6BBC
ORCID iD
0000-0003-0405-1342

Email addresses

  • filipemorais@ua.pt (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2023/03/01 - 2027/03/01
Ongoing
 Química Sustentável (Doutoramento)
Universidade de Aveiro, Portugal
2017/09/01 - 2019/07/24
Concluded
 Bioquímica (Mestrado)
Major in Clínica
Universidade de Aveiro, Portugal
"Efeito do exercício físico na modulação do ventrículo direito induzida pela hipertensão arterial pulmonar" (THESIS/DISSERTATION)
 17
2013/10/01 - 2017/07/01
Concluded
 Bioquímica (Licenciatura)
Universidade de Aveiro, Portugal
"Novos Conjungados benzo-porfirínicos: Síntese e avaliação anti-microbiana" (THESIS/DISSERTATION)
 15
Affiliation

Others

Category
Host institution 		Employer
2021/01/04 - 2021/11/01 Estágio - Controlo de Qualidade, produção, planeamento e logística HardLevel Energias Renováveis, Portugal
2020/09 - 2021/04 Operador Logística Leroy Merlin , Portugal
2020/04 - 2020/09 Técnico Auxiliar de Farmácia - BackOffice Farmácia Lemos , Portugal
2017/04/13 - 2020/02/29 Gerente de departamento de Serviço ao cliente OlhaOutro Gestão Hoteleira Unipessoal Lda, Portugal
Projects

Grant

Designation Funders
2023/03/01 - Current Development of porphyrin-triphenylphosphonium-based photosensitizers
UI/BD/154486/2022
PhD Student Fellow
Universidade de Aveiro, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2022/04/01 - 2023/02/28 Desenvolvimento de fotossensibilizadores porfirina-trifenilfosfónio para a inativação fotodinâmica de microrganismos
EXPL/QUI-QOR/0586/2021
Research Fellow
Universidade de Aveiro, Portugal
 Associação para a Inovação e Desenvolvimento da FCT
Concluded
Outputs

Publications

Conference abstract
  1. Moura, Nuno M. M.; Reis, Melani; Morais, Filipe; Chaves, Inês; Vieira, Cátia; M. Amparo F. Faustino; Almeida, Adelaide; M.G.P.M.S Neves. "Strategies to enhance antimicrobial photodynamic activity of porphyrin-based photosensitizers". Paper presented in 6th International Caparica Conference on Chromogenic and Emissive Materials, Costa da Caparica, 2024.
    Accepted
Conference paper
  1. Filipe M. P. Morais; Cátia Vieira; Ana T. P. C. Gomes; Maria A. F. Faustino; Adelaide Almeida; Maria G. P. M. S. Neves; Nuno M. M. Moura. "Synthetic Access to Tetracationic Benzoporphyrins and Their Role as Photosensitizers towards Gram-Negative Escherichia coli ". 2022.
    10.3390/ecsoc-26-13587
Conference poster
  1. Morais, Filipe; Inês Chaves; Vieira, Cátia; Maria Bartolomeu; Ana T.P.C. Gomes; M. Amparo F. Faustino; M. Graça P. M. S. Neves; et al. "Triphenylphosphonium-Modified Metalloporphyrins as Effective Photosensitizers for Antibacterial Photodynamic Therapy". Paper presented in 5th International Caparica Christmas Conference on Translational Chemistry, 2024.
  2. Morais, Filipe; Chaves, Inês; Vieira, Cátia; M. Amparo F. Faustino; Almeida, Adelaide; M.G.P.M.S Neves; Lodeiro, Carlos; Moura, Nuno M. M.. "Triphenylphosphonium porphyrin derivatives photosensitizers: does the charge matter?". Paper presented in 6th International Caparica Conference on Chromogenic and Emissive Materials, 2024.
  3. Morais, Filipe; Chaves, Inês; Vieira, Cátia; M. Amparo F. Faustino; Almeida, Adelaide; M.G.P.M.S Neves; Moura, Nuno M. M.. "Development of Porphyrin-triPhenylPosphonium PhotoSensitizers for Photodynamic Inactivation of Microorganisms". Paper presented in XXVII Encontro Luso-Galego de Química, 2023.
  4. Morais, Filipe; Sofia Pedrosa; Vieira, Cátia; Ana T.P.C. Gomes; M. Amparo F. Faustino; Almeida, Adelaide; M. Graça P. M. S. Neves; Moura, Nuno M. M.. "Unraveling the Photodynamic Activity of Cationic Dibenzoporphyrin-Based Photosensitizers against Escherichia coli". Paper presented in XVIII Encontro Nacional da SPQ, 2023.
  5. Morais, Filipe; Maria da Graça de Pinho Morgado Silva Neves; Carlos Lodeiro Espiño; Moura, Nuno M. M.. "Cationic meso-Substituted Porphyrins: Synthesis and Antimicrobial Activity". Paper presented in Ciencia 2023, 2023.
  6. Morais, Filipe; Cátia Vieira; Ana T. P. C. Gomes; Maria A. F. Faustino; Adelaide Almeida; Maria G. P. M. S Neves; Nuno M. M. Moura. Corresponding author: Nuno M. M. Moura. "Preparation of benzoporphyrin-base photosensitizers". 2022.
  7. Morais, Filipe; Nogueira-Ferreira, Rita; Rocha, Hugo; José A. Duarte; Vilarinho, Laura; F. Silva, Ana ; ADELINO LEITE-MOREIRA; et al. Corresponding author: Morais, Filipe. "Impact of exercise training on cardiac metabolic remodelling in a pulmonary arterial hypertension animal model". Paper presented in 1st Conference of the doctoral program in metabolism – Clinical and experimental diabesity: looking by a different prism, 2022.
  8. Morais, Filipe; Vieira, Cátia; Gomes, A.T.P.C.; Faustino, M.A.F.; Almeida, Adelaide; Maria G.P.M.S. Neves; Moura, Nuno M. M.. "Preparation of benzoporphyrin-based photosensitizers". Paper presented in XXVI Encontro Galego-Português de Química, 2022.
  9. Ana. R. Monteiro; Luca Menilli; Filipe M. P. Morais; Ana T.P.C. Gomes; Moura, Nuno M. M.; Sara Fateixa; Maria A. F. Faustino; et al. ""Graphene Oxide and Graphene Quantum Dots as delivery systems of Cationic Porphyrins and their antiproliferative activity towards T24 human vesical Cancer Cells". Paper presented in Jornadas do CICECO, 2020.
  10. A. R. Monteiro; L. Menilli; S. Lazzarotto; Morais, Filipe; A. T. P. C. Gomes; N. M. M. Moura; S. Fateixa; G. Miolo; et al. "Functionalization of graphene oxide with porphyrins". Paper presented in Jornadas do CICECO, 2019.
  11. Monteiro, Ana R.; L. Menilli; S. Lazzarotto; Morais, Filipe; A. Gomes; N. M. M. Moura. "Photocytotoxicity of Phorphyrin@GO hybrids against cancer cells". Paper presented in 8th Iberian Meeting on Colloids and Interfaces (RICI8), 2019.
  12. Monteiro, Ana R.; L. Menilli; S. Lazzarotto; F. Morais; A. Gomes; N. M. M. Moura. "Photocytotoxicity of porphyrin@GO hybrids against cancer cells". Paper presented in 8th Iberian Meeting on Colloids and Interfaces (RICI8), 2019.
  13. F. Morais; Rita Maria Pinho Ferreira; Daniel Moreira Gonçalves. "The role of exercise training in the modulation of molecular pathways underlying right ventricle dysfunction in pulmonary arterial hypertension". Paper presented in Biochemistry Day - Universidade de Aveiro, 2019.
  14. F. Morais; Catarina Costa; André Teodoro. "A bioquímica do vício sexual". Paper presented in Biochemistry Day - Universidade de Aveiro, 2018.
  15. F. Morais; A. Gomes; Almeida, Adelaide; Maria da Graça de Pinho Morgado Silva Neves. "New cationic benzoporphyrins: Synthesis and antimicrobial activity". Paper presented in Biochemistry Day - Universidade de Aveiro, 2017.
Journal article
  1. Inês Chaves; Morais, Filipe; Vieira, Cátia; Maria Bartolomeu; Ana T.P.C. Gomes; M. Amparo F. Faustino; M. Graça P. M. S. Neves; Almeida, Adelaide; Moura, Nuno M. M.. Corresponding author: Moura, Nuno M. M.. "The impact of metal ions on the photo-antibacterial efficiency of metalloporphyrins with triphenylphosphonium units". Inorganic Chemistry Communications (2025):
    Submitted
  2. Chaves, Inês; Morais, Filipe; Vieira, Cátia; Bartolomeu, Maria; M. Amparo F. Faustino; M.G.P.M.S Neves; Almeida, Adelaide; Moura, Nuno M. M.. "Can porphyrin-triphenylphosphonium conjugates enhance the photosensitizer performance towards bacterial strains?". Journal of Photochemistry and Photobiology B (2024):
    Published • 10.1021/acsabm.4c00659
  3. Filipe Morais; Rita Nogueira-Ferreira; Hugo Rocha; José A. Duarte; Laura Vilarinho; Ana F. Silva; Adelino Leite-Moreira; et al. "Exercise training counteracts the cardiac metabolic remodelling induced by experimental pulmonary arterial hypertension". Archives of Biochemistry and Biophysics (2022): https://doi.org/10.1016/j.abb.2022.109419.
    10.1016/j.abb.2022.109419
  4. Moura, Nuno; Ramos, Catarina; Mesquita, Mariana; Monteiro, Ana; Gamelas, Sara; Morais, Filipe; Dias, Cristina; et al. "Can porphyrinoids defeat cancer?". Research@UA 12 61 (2022): https://proa.ua.pt/index.php/researchua/issue/view/1044/327.
    Open access • Published
  5. Menilli, Luca; Monteiro, Ana R.; Lazzarotto, Silvia; Morais, Filipe M. P.; Gomes, Ana T. P. C.; Moura, Nuno M. M.; Fateixa, Sara; et al. "Graphene Oxide and Graphene Quantum Dots as Delivery Systems of Cationic Porphyrins: Photo-Antiproliferative Activity Evaluation towards T24 Human Bladder Cancer Cells". Pharmaceutics 13 9 (2021): 1512. http://dx.doi.org/10.3390/pharmaceutics13091512.
    10.3390/pharmaceutics13091512
Newspaper article
  1. Nuno M. M. Moura; Catarina I. V. Ramos; Mariana Q. Mesquita; Ana R. Monteiro; Sara Gamelas; Morais, Filipe; Cristina J. Dias; et al. "Can porphyrinoids defeat cancer?", Research@ua, 2022, https://proa.ua.pt/index.php/researchua/issue/view/1044/327.
Thesis / Dissertation
  1. "Effect of exercise training on right ventricular remodelling induced by pulmonary arterial hypertension". Master, 2019. http://hdl.handle.net/10773/27761.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/11/13 The impact of metal on the antimicrobial Photodynamic Efficiency of Metalloporphyrins with Triphenylphosphonium Units: A Comparative Study XXVIII Encontro Luso-Galego de Química
(Vigo, Spain)
2024/07/21 Boosting the photosensitizer efficiency of meso-tetraarylporphyrins towards bacterial strains by conjugation with triphenylphosphonium salts International Society of Heterocycles Chemistry Congress
(Costa da Caparica, Portugal)
2024/07/07 Porphyrin-triphenylphosphium derivatives photosensitizers: does the charge matter? 6th International Caparica Conference of Chromogenic and Emissive Materials
(Costa da Caparica, Portugal)
2023/11/22 Development of Porphyrin-triPhenylPosphonium PhotoSensitizers for Photodynamic Inactivation of Microorganisms XXVII Encontro Luso-Galego de Química
(Porto, Portugal)
2023/04/21 Cationic benzoporphyrins: synthesis and antimicrobial activity Sour turned Sweet: Glycans bridging technology & precision medicine
COST (Iasi, Romania)
2023/03/08 Tetrapyrrolic macrocycles: an insight on their biological importance, occurrence, and applications Conference on Applied (Bio) Geochemistry (CAG 2023)
Higher School of Technology, Fkih Ben Salah (Morocco)
2022/11/16 Recent advances in cancer therapies via carbon nanomaterials functionalized with porphyrins and analogues
Faculty of Chemistry - University of Santiago Compostela (Santiago de Compostela, Spain)
2020/11/05 Antiproliferative activity of cationic porphyrins functionalized with graphene oxide and graphene quantum dots in cancer cells Photodynamic Therapy and Photodiagnosis (PDT-PDD)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/07/24 - 2023/07/26 XVIII Encontro Nacional da SPQ (2023/07/24 - 2023/07/26)
Congress (Other)
 Universidade de Aveiro, Portugal
2023/07/24 - 2023/07/26 Volunteer at organization of XVIII Encontro Nacional da SPQ (2023/07/24 - 2023/07/26)
Congress (Other)
 Universidade de Aveiro, Portugal
2022/07/18 - 2022/07/22 Academia de Verão - Universidade de Aveiro (16ª Edição) Monitor científico nas atividades laboratoriais (2022/07/18 - 2022/07/22)
Other (Other)
 Universidade de Aveiro, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2016/03/18 - 2016/03/21 Encontro Nacional de Estudantes: Participação em atividades como: palestras, workshops, um debate, atividades desportivas e culturais. Nestas áreas, cobrem-se componentes científicas, de saídas profissionais e de caráter interpessoal, transversais a todo o programa. A presença de oradores nacionais e internacionais como Arsélio Pato de Carvalho, Pedro Beltrão, Paula Salgado, Paulo Oliveira, Duarte Nuno Vieira, João Ramalho Santos, Valdemar Máximo permitiram abordar as seguintes temáticas: bioinformática, biologia molecular e ciências forenses.
Meeting
 Encontro Nacional de Estudantes
Universidade de Coimbra, Portugal
Distinctions

Award

2024 2nd Shotgun Poster Prize
2022 Editor's Choice Collection da Pharmaceutics (MDPI)
2019 Best Poster at the 8th Iberian Meeting on Colloids and Interfaces (RICI8)