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I hold a masters' degree in Pharmaceutical Biotechnology by the Faculty of Pharmacy of the University de Coimbra (awarded in 2019/07) and bachelors' degree in Biochemistry by the Faculty of Sciences and Technology of the same university (awarded in 2018/03). I will also start to attend the PhD in Biomedicine at the Universitat Pompeu Fabra (beginning in October this year). Currently, I am a contracted researcher in Anaxomics Biotech S.L., under a Horizon-2020/Marie Sklodowska-Curie grant (agreement No 765912). I've been able to publish two articles in journals and three sections of books; organized two events and participated in other four. I am a participating researcher in one international project. My areas of interest are Gene-based Diagnostics and Therapeutic Interventions, Bioinformatics and Health-Related Biotechnology in coordination with my base-training in Biochemistry. Within my professional activity, I've interacted with 30 collaborators via co-authorship of scientific papers. Most frequent Keywords: Machine Learning; Pharmacogenomics; Small Molecules; Biologics; Biosimilars; Clinical Medicine; Oncology; Cancer; Biochemistry; Pharmacology; Data-science; Artificial Intelligence; Oncology; Genomics; Bioinformatics.
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Identification

Personal identification

Full name
PEDRO MATOS PINTO SANTOS FILIPE
Date of birth
1996/04/25

Citation names

  • Matos-Filipe, Pedro

Author identifiers

Ciência ID
FA13-144F-4980
ORCID iD
0000-0003-0492-0683
Google Scholar ID
tHuuZJgAAAAJ

Email addresses

  • pedro.filipe@anaxomics.com (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Gene-based Diagnostics and Therapeutic Interventions
  • Exact Sciences - Computer and Information Sciences - Bioinformatics
  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
  • Natural sciences - Biological Sciences - Biochemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Proficiency (C2) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Upper intermediate (B2) Advanced (C1) Intermediate (B1) Upper intermediate (B2) Intermediate (B1)
Education
Degree Classification
2020/06 - 2024/11
Concluded
 Doctorat en Biomedicina (Doctor of Philosophy)
Universitat Pompeu Fabra, Spain
"AI Modelling of Real-world Patients: applications in Prostate Cancer" (THESIS/DISSERTATION)
2017/10 - 2019/07
Concluded
 Pharmaceutical Biotechnology (Mestrado)
Major in Sem especialização
Universidade de Coimbra Faculdade de Farmácia, Portugal
"A Computational Method to Predict the Combinatory Effect of Drugs in Cancer" (THESIS/DISSERTATION)
 17
2014/09/11 - 2018/03/18
Concluded
 Biochemistry (Licenciatura)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
"Prediction of Secondary Structure of Proteins - an empirical approach to the process" (THESIS/DISSERTATION)
 13
Affiliation

Science

Category
Host institution 		Employer
2020/02/03 - Current Contracted Researcher (Research) Anaxomics, Spain
Anaxomics, Spain
(...)
2019/11/15 - 2020/01/31 Contracted Researcher (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2017/09/17 - 2019/09/29 Research Trainee (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
CNC.IBILI, Portugal
(...)
Projects

Contract

Designation Funders
2020/02/03 - Current ProEVLifeCycle - The prostate cancer Extracellular Vesicle Network
860303
Researcher
Anaxomics, Spain
 EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
Ongoing
Outputs

Publications

Book chapter
  1. António J. Preto; Pedro Matos-Filipe; José G. de Almeida; Joana Mourão; Irina S. Moreira. "Predicting Hot Spots Using a Deep Neural Network Approach". 267-288. Springer {US, 2021.
    10.1007/978-1-0716-0826-5_13
  2. Barreto, Carlos A.V.; Baptista, Salete J.; Preto, António José; Matos-Filipe, Pedro; Mourão, Joana; Melo, Rita; Moreira, Irina. "Prediction and targeting of GPCR oligomer interfaces". In Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors, 105-149. Elsevier, 2020.
    10.1016/bs.pmbts.2019.11.007
  3. Preto, A.J.; Matos-Filipe, Pedro; Almeida, José G.; Mourão, Joana; Moreira, I.S.. "Predicting Hot-Spots using a Deep Neural Network Approach". In Artificial Neural Networks, edited by Cartwright, H.. Springer, 2020.
    In press
  4. Preto, António J.; Matos-Filipe, Pedro; Koukos, Panagiotis I.; Renault, Pedro; Sousa, Sérgio F.; Moreira, Irina S.. "Structural Characterization of Membrane Protein Dimers". In Protein Supersecondary Structures, edited by Alexander E. Kister, 403-436. Humana Press, 2019.
    Published • 10.1007/978-1-4939-9161-7_21
Conference abstract
  1. Matos-Filipe, Pedro; Preto, A.J.; Almeida, José G.; Koukos, Panagiotis; Bonvin, Alexandre; Moreira, I.S.. "MENSAdb: A Major Structural Statistical Analysis of Membrane Protein Dimers". Paper presented in 6th Meeting of Young Researchers in Structural Computational Biology, Porto, 2018.
  2. Filipe, Pedro; Preto, António; Koukos, Panos; Bonvin, Alexandre; Moreira, Irina. "Alpha-helical and beta-sheet membrane- membrane protein dimers: centralizing information". Paper presented in Proceedings of the MOL2NET 2017, International Conference on Multidisciplinary Sciences, Coimbra, 2017.
    Accepted • 10.3390/mol2net-03-05107
Journal article
  1. Valentin Junet; Pedro Matos-Filipe; Juan Manuel García-Illarramendi; Esther Ramírez; Baldo Oliva; Judith Farrés; Xavier Daura; José Manuel Mas; Rafael Morales. "A decision support system based on artificial intelligence and systems biology for the simulation of pancreatic cancer patient status". CPT: Pharmacometrics & Systems Pharmacology (2023): https://doi.org/10.1002/psp4.12961.
    10.1002/psp4.12961
  2. António J Preto; Pedro Matos-Filipe; Joana Mourão; Irina S Moreira. "SYNPRED: prediction of drug combination effects in cancer using different synergy metrics and ensemble learning". GigaScience (2022): https://doi.org/10.1093/gigascience/giac087.
    10.1093/gigascience/giac087
  3. Artigas, L.; Coma, M.; Matos-Filipe, P.; Aguirre-Plans, J.; Farrés, J.; Valls, R.; Fernandez-Fuentes, N.; et al. "In-silico drug repurposing study predicts the combination of pirfenidone and melatonin as a promising candidate therapy to reduce SARS-CoV-2 infection progression and respiratory distress caused by cytokine storm". PLoS ONE 15 10 October (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85092226708&partnerID=MN8TOARS.
    10.1371/journal.pone.0240149
  4. Matos-Filipe, Pedro; António J. Preto; Panagiotis I. Koukos; Joana Mourão; Alexandre M.J.J. Bonvin; Irina S. Moreira. "MENSADB: A Thorough Structural Analysis of Membrane Protein Dimers". Biomolecules (q-bio.BM) (2019): arXiv:1902.02321.
    Open access • Published • 10.1093/database/baab013
  5. Melo, Rita; Lemos, Agostinho; Preto, António J.; Bueschell, Beatriz; Matos-Filipe, Pedro; Barreto, Carlos; Almeida, José G.; et al. "An overview of antiretroviral agents for treating HIV infection in paediatric population". Current Medicinal Chemistry 25 (2018): http://dx.doi.org/10.2174/0929867325666180904123549.
    10.2174/0929867325666180904123549
Preprint
  1. Pedro Matos-Filipe; Baldo Oliva; Judith Farrés; José Manuel Mas. "Integration of expression datasets to identify biomarkers for accurate Gleason scoring in Prostate Cancer". 2024. https://doi.org/10.1101/2024.08.21.608965.
    10.1101/2024.08.21.608965
  2. Pedro Matos-Filipe; Juan Manuel García-Illarramendi; Guillem Jorba; Baldo Oliva; Judith Farrés; José Manuel Mas. "The usage of transcriptomics datasets as sources of Real-World Data for clinical trialling". 2022. https://doi.org/10.1101/2022.11.10.515995.
    10.1101/2022.11.10.515995
Thesis / Dissertation
  1. Matos-Filipe, Pedro. "A Computational Method to Predict the Combinatory Effect of Drugs in Cancer". 2019.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2018/12 An in-silico Predictor of Protein Dimer Interfaces 6th Meeting of Young Researchers in Structural Computational Biology
(Porto, Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2017/06/01 - 2017/12/22 Meeting of Young Structural Computational Biology Researchers (2017/12/22 - 2017/12/22)
Meeting (Member of the Organising Committee)
 Universidade de Coimbra, Portugal
2015/06 - 2016/06 IX Biochemistry Students' National Meeting (2016/04/18 - 2016/04/21)
Meeting (Member of the Organising Committee)
 Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2018/12/21 - 2018/12/21 Participação em "Meeting of Young Structural Computational Biology Researchers".
Meeting
 Meeting of Young Structural Computational Biology Researchers
Universidade do Porto, Portugal
2018/09/27 - 2018/09/28 Symposium under the motto "Translational Science: From Academia to Industry", where members of academia and industry shared their perspectives on the socioeconomic and corporate facades of drugs R&D.
Symposium
 1st Drugs R&D PhD Symposium
Universidade de Coimbra Faculdade de Farmácia, Portugal
2016/02/19 - 2016/02/19 Participação em palestras e workshop de Propriedade Intelectual da III Reunião Nacional de Bioquímicos.
Meeting
 III Reunião Nacional de Bioquímicos
Associação Nacional de Bioquímicos, Portugal

Universidade de Coimbra, Portugal
2016/02/19 - 2016/02/19 Intellectual Property Workshop
Workshop
 Intellectual Property Workshop
Associação Nacional de Bioquímicos, Portugal

Association member

Society Organization name Role
2019/03/17 - Current Associação Nacional de Bioquímicos (National Association of Biochemists) Member
2017/12 - 2018/12 Associação Académica de Coimbra (Coimbra Students' Union) Chairman of the board of the General Assembly
2017/01 - 2017/12 Associação Académica de Coimbra (Coimbra Students' Union) General coordinator for Educational Policies
2016/01 - 2017/01 Associação Académica de Coimbra (Coimbra Students' Union) General coordinator for Social Support
2015/06 - 2016/01 Núcleo de Estudantes de Bioquímica da Associação Académica de Coimbra (Biochemistry Commission of the Coimbra Students' Union) Secretary of the board of the General Assembly
Distinctions

Award

2022 Young Scientist Travel Award (YSTA)
ecopa - European Consensus-Platform on Alternatives, Belgium