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I hold a masters' degree in Pharmaceutical Biotechnology by the Faculty of Pharmacy of the University de Coimbra (awarded in 2019/07) and bachelors' degree in Biochemistry by the Faculty of Sciences and Technology of the same university (awarded in 2018/03). I will also start to attend the PhD in Biomedicine at the Universitat Pompeu Fabra (beginning in October this year). Currently, I am a contracted researcher in Anaxomics Biotech S.L., under a Horizon-2020/Marie Sklodowska-Curie grant (agreement No 765912). I've been able to publish two articles in journals and three sections of books; organized two events and participated in other four. I am a participating researcher in one international project. My areas of interest are Gene-based Diagnostics and Therapeutic Interventions, Bioinformatics and Health-Related Biotechnology in coordination with my base-training in Biochemistry. Within my professional activity, I've interacted with 30 collaborators via co-authorship of scientific papers. Most frequent Keywords: Machine Learning; Pharmacogenomics; Small Molecules; Biologics; Biosimilars; Clinical Medicine; Oncology; Cancer; Biochemistry; Pharmacology; Data-science; Artificial Intelligence; Oncology; Genomics; Bioinformatics.
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Identificação

Identificação pessoal

Nome completo
PEDRO MATOS PINTO SANTOS FILIPE
Data de nascimento
1996/04/25

Nomes de citação

  • Matos-Filipe, Pedro

Identificadores de autor

Ciência ID
FA13-144F-4980
ORCID iD
0000-0003-0492-0683
Google Scholar ID
tHuuZJgAAAAJ

Endereços de correio eletrónico

  • pedro.filipe@anaxomics.com (Professional)

Websites

Domínios de atuação

  • Medical and Health Sciences - Medical Biotechnology - Gene-based Diagnostics and Therapeutic Interventions
  • Exact Sciences - Computer and Information Sciences - Bioinformatics
  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
  • Natural sciences - Biological Sciences - Biochemistry

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Portuguese (Idioma materno)
English Advanced (C1) Proficiency (C2) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Upper intermediate (B2) Advanced (C1) Intermediate (B1) Upper intermediate (B2) Intermediate (B1)
Formação
Grau Classificação
2020/06 - 2024/11
Concluded
 Doctorat en Biomedicina (Doctor of Philosophy)
Universitat Pompeu Fabra, Spain
"AI Modelling of Real-world Patients: applications in Prostate Cancer" (TESE/DISSERTAÇÃO)
2017/10 - 2019/07
Concluded
 Pharmaceutical Biotechnology (Mestrado)
Especialização em Sem especialização
Universidade de Coimbra Faculdade de Farmácia, Portugal
"A Computational Method to Predict the Combinatory Effect of Drugs in Cancer" (TESE/DISSERTAÇÃO)
 17
2014/09/11 - 2018/03/18
Concluded
 Biochemistry (Licenciatura)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
"Prediction of Secondary Structure of Proteins - an empirical approach to the process" (TESE/DISSERTAÇÃO)
 13
Percurso profissional

Science

Categoria Profissional
Instituição de acolhimento 		Empregador
2020/02/03 - Atual Contracted Researcher (Research) Anaxomics, Spain
Anaxomics, Spain
(...)
2019/11/15 - 2020/01/31 Contracted Researcher (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2017/09/17 - 2019/09/29 Research Trainee (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
CNC.IBILI, Portugal
(...)
Projetos

Contract

Designação Financiadores
2020/02/03 - Atual ProEVLifeCycle - The prostate cancer Extracellular Vesicle Network
860303
Researcher
Anaxomics, Spain
 EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
Ongoing
Produções

Publications

Book chapter
  1. António J. Preto; Pedro Matos-Filipe; José G. de Almeida; Joana Mourão; Irina S. Moreira. "Predicting Hot Spots Using a Deep Neural Network Approach". 267-288. Springer {US, 2021.
    10.1007/978-1-0716-0826-5_13
  2. Barreto, Carlos A.V.; Baptista, Salete J.; Preto, António José; Matos-Filipe, Pedro; Mourão, Joana; Melo, Rita; Moreira, Irina. "Prediction and targeting of GPCR oligomer interfaces". In Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors, 105-149. Elsevier, 2020.
    10.1016/bs.pmbts.2019.11.007
  3. Preto, A.J.; Matos-Filipe, Pedro; Almeida, José G.; Mourão, Joana; Moreira, I.S.. "Predicting Hot-Spots using a Deep Neural Network Approach". In Artificial Neural Networks, editado por Cartwright, H.. Springer, 2020.
    In press
  4. Preto, António J.; Matos-Filipe, Pedro; Koukos, Panagiotis I.; Renault, Pedro; Sousa, Sérgio F.; Moreira, Irina S.. "Structural Characterization of Membrane Protein Dimers". In Protein Supersecondary Structures, editado por Alexander E. Kister, 403-436. Humana Press, 2019.
    Published • 10.1007/978-1-4939-9161-7_21
Conference abstract
  1. Matos-Filipe, Pedro; Preto, A.J.; Almeida, José G.; Koukos, Panagiotis; Bonvin, Alexandre; Moreira, I.S.. "MENSAdb: A Major Structural Statistical Analysis of Membrane Protein Dimers". Trabalho apresentado em 6th Meeting of Young Researchers in Structural Computational Biology, Porto, 2018.
  2. Filipe, Pedro; Preto, António; Koukos, Panos; Bonvin, Alexandre; Moreira, Irina. "Alpha-helical and beta-sheet membrane- membrane protein dimers: centralizing information". Trabalho apresentado em Proceedings of the MOL2NET 2017, International Conference on Multidisciplinary Sciences, Coimbra, 2017.
    Accepted • 10.3390/mol2net-03-05107
Journal article
  1. Valentin Junet; Pedro Matos-Filipe; Juan Manuel García-Illarramendi; Esther Ramírez; Baldo Oliva; Judith Farrés; Xavier Daura; José Manuel Mas; Rafael Morales. "A decision support system based on artificial intelligence and systems biology for the simulation of pancreatic cancer patient status". CPT: Pharmacometrics & Systems Pharmacology (2023): https://doi.org/10.1002/psp4.12961.
    10.1002/psp4.12961
  2. António J Preto; Pedro Matos-Filipe; Joana Mourão; Irina S Moreira. "SYNPRED: prediction of drug combination effects in cancer using different synergy metrics and ensemble learning". GigaScience (2022): https://doi.org/10.1093/gigascience/giac087.
    10.1093/gigascience/giac087
  3. Artigas, L.; Coma, M.; Matos-Filipe, P.; Aguirre-Plans, J.; Farrés, J.; Valls, R.; Fernandez-Fuentes, N.; et al. "In-silico drug repurposing study predicts the combination of pirfenidone and melatonin as a promising candidate therapy to reduce SARS-CoV-2 infection progression and respiratory distress caused by cytokine storm". PLoS ONE 15 10 October (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85092226708&partnerID=MN8TOARS.
    10.1371/journal.pone.0240149
  4. Matos-Filipe, Pedro; António J. Preto; Panagiotis I. Koukos; Joana Mourão; Alexandre M.J.J. Bonvin; Irina S. Moreira. "MENSADB: A Thorough Structural Analysis of Membrane Protein Dimers". Biomolecules (q-bio.BM) (2019): arXiv:1902.02321.
    Acesso aberto • Published • 10.1093/database/baab013
  5. Melo, Rita; Lemos, Agostinho; Preto, António J.; Bueschell, Beatriz; Matos-Filipe, Pedro; Barreto, Carlos; Almeida, José G.; et al. "An overview of antiretroviral agents for treating HIV infection in paediatric population". Current Medicinal Chemistry 25 (2018): http://dx.doi.org/10.2174/0929867325666180904123549.
    10.2174/0929867325666180904123549
Preprint
  1. Pedro Matos-Filipe; Baldo Oliva; Judith Farrés; José Manuel Mas. "Integration of expression datasets to identify biomarkers for accurate Gleason scoring in Prostate Cancer". 2024. https://doi.org/10.1101/2024.08.21.608965.
    10.1101/2024.08.21.608965
  2. Pedro Matos-Filipe; Juan Manuel García-Illarramendi; Guillem Jorba; Baldo Oliva; Judith Farrés; José Manuel Mas. "The usage of transcriptomics datasets as sources of Real-World Data for clinical trialling". 2022. https://doi.org/10.1101/2022.11.10.515995.
    10.1101/2022.11.10.515995
Thesis / Dissertation
  1. Matos-Filipe, Pedro. "A Computational Method to Predict the Combinatory Effect of Drugs in Cancer". 2019.
Atividades

Oral presentation

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2018/12 An in-silico Predictor of Protein Dimer Interfaces 6th Meeting of Young Researchers in Structural Computational Biology
(Porto, Portugal)

Event organisation

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2017/06/01 - 2017/12/22 Meeting of Young Structural Computational Biology Researchers (2017/12/22 - 2017/12/22)
Meeting (Member of the Organising Committee)
 Universidade de Coimbra, Portugal
2015/06 - 2016/06 IX Biochemistry Students' National Meeting (2016/04/18 - 2016/04/21)
Meeting (Member of the Organising Committee)
 Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Event participation

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2018/12/21 - 2018/12/21 Participação em "Meeting of Young Structural Computational Biology Researchers".
Meeting
 Meeting of Young Structural Computational Biology Researchers
Universidade do Porto, Portugal
2018/09/27 - 2018/09/28 Symposium under the motto "Translational Science: From Academia to Industry", where members of academia and industry shared their perspectives on the socioeconomic and corporate facades of drugs R&D.
Symposium
 1st Drugs R&D PhD Symposium
Universidade de Coimbra Faculdade de Farmácia, Portugal
2016/02/19 - 2016/02/19 Participação em palestras e workshop de Propriedade Intelectual da III Reunião Nacional de Bioquímicos.
Meeting
 III Reunião Nacional de Bioquímicos
Associação Nacional de Bioquímicos, Portugal

Universidade de Coimbra, Portugal
2016/02/19 - 2016/02/19 Intellectual Property Workshop
Workshop
 Intellectual Property Workshop
Associação Nacional de Bioquímicos, Portugal

Association member

Nome da associação Tipo de participação
2019/03/17 - Atual Associação Nacional de Bioquímicos (National Association of Biochemists) Member
2017/12 - 2018/12 Associação Académica de Coimbra (Coimbra Students' Union) Chairman of the board of the General Assembly
2017/01 - 2017/12 Associação Académica de Coimbra (Coimbra Students' Union) General coordinator for Educational Policies
2016/01 - 2017/01 Associação Académica de Coimbra (Coimbra Students' Union) General coordinator for Social Support
2015/06 - 2016/01 Núcleo de Estudantes de Bioquímica da Associação Académica de Coimbra (Biochemistry Commission of the Coimbra Students' Union) Secretary of the board of the General Assembly
Distinções

Award

2022 Young Scientist Travel Award (YSTA)
ecopa - European Consensus-Platform on Alternatives, Belgium