???global.info.a_carregar???
My name is Rita Sofia Cebola Rebelo Manuel. I am a PhD Student at the Bacterial Energy Metabolism Lab in ITQB NOVA since October 2020, working in the Biotechnology and Biocatalysis fields. I finished my BSc in Cellular and Molecular Biology on July 2017 (final evaluation: 15), with an internship at the Pathology Department of the University of Cambridge, England, and my MSc in Biotechnology for Sustainability from Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA) on November 2019 (final evaluation: 18). My Master's dissertation research in the Synthetic Biology field - Influence of Ferredoxin, Iron-Sulfur Carrier and Cobalamin Importer Overexpression on the Production of High-value Products by Escherichia coli - was accomplished at the Bionanosciences Department of TU Delft, Netherlands, with one oral presentation in the conference 2019 Synthetic Biology: Engineering, Evolution & Design, and part of an EU financed project. Thus, my experience relies on the Engineering Sciences field, essentially Environmental Biotechnology and Synthetic Biology, and on the Biological Sciences field, with an emphasis on Cellular and Molecular Biology.
Read full resume ↓
Identification

Personal identification

Full name
Rita Sofia Cebola Rebelo Manuel
Gender
Female

Citation names

  • Rebelo Manuel, Rita

Author identifiers

Ciência ID
F910-CE53-F0FA
ORCID iD
0000-0001-8068-2053

Email addresses

  • rs.manuel@itqb.unl.pt (Professional)

Knowledge fields

  • Engineering and Technology - Environmental Biotechnology
  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Molecular Biology

Languages

Language Speaking Reading Writing Listening Peer-review
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Education
Degree Classification
2020/10 - 2024/10
Ongoing
 Molecular Biosciences (Doutoramento)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2017/09 - 2019/11/25
Concluded
 Biotechnology for Sustainability (Mestrado)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
"Influence of Ferredoxin, Iron-Sulfur Carrier and Cobalamin Importer Overexpression on the Production of High-value Products by Escherichia coli (at TU Delft)" (THESIS/DISSERTATION)
 18
2014/09 - 2017/07/05
Concluded
 Cell and Molecular Biology (Licenciatura)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
 15
Affiliation

Science

Category
Host institution 		Employer
2020/10 - 2024/10 Research Trainee (Research) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2020/01/07 - 2020/10 Research Trainee (Research) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2018/10 - 2019/04 Research Trainee (Research) Technische Universiteit Delft, Netherlands
2017/07 - 2017/08 Research Trainee (Research) Instituto Superior de Ciências da Saúde Egas Moniz, Portugal
2017/01 - 2017/02 Research Trainee (Research) University of Cambridge, United Kingdom
Projects

Grant

Designation Funders
2020/10 - 2024/10 Improving a highly active tungsten-dependent formate dehydrogenase for biocatalytic reduction of CO2
DFA/BD/7897/2020
PhD Student Fellow
Fundação para a Ciência e a Tecnologia
2020/01 - 2020/10 Reduction of CO2 for sustainable biofuel production
CTQB/001/BI/2020
Research Fellow
CTQB
2018/10 - 2019/04 Erasmus+
29191/WORK+3/419/SMT
Master Student Fellow
Erasmus Plus
Outputs

Publications

Conference abstract
  1. Ana Rita Oliveira; Cristiano Mota; Rita Rebelo Manuel; Guilherme Vilela-Alves; Neide Pedrosa; Vincent Fourmond; Kateryna Klymanska; et al. "An Allosteric Redox Switch Enables Oxygen Protection of a Formate Dehydrogenase from Desulfovibrio Vulgaris Hildenborough". 2023.
  2. Rita Rebelo Manuel; Ana Rita Oliveira; Inês Cardoso Pereira. "Specific Active Site Residues of a Highly Active Formate Dehydrogenase Play Important Roles in the Catalytic Mechanism". 2023.
  3. Rita Rebelo Manuel; Bruno Guigliarelli; Inês Cardoso Pereira. "Insights into the catalytic mechanism of FdhAB from Desulfovibrio vulgaris Hildenborough". 2023.
Conference paper
  1. Fernández-Fueyo, Elena; Shomar, Helena; Rebelo Manuel, Rita; van de Broek, Niels; Bokinsky, Gregory. "Activating Foreign FeS Enzymes in Escherichia coli". Paper presented in 2019 Synthetic Biology: Engineering, Evolution & Design (SEED), Nova Iorque, 2019.
Conference poster
  1. Rebelo Manuel, Rita; Oliveira, Ana Rita; Inês Antunes Cardoso Pereira. "Investigating the mechanism of the W-FdhAB from Desulfovibrio vulgaris Hildenborough". Paper presented in TIMB3 Final Meeting, 2022.
  2. Rebelo Manuel, Rita; Oliveira, Ana Rita; Inês Antunes Cardoso Pereira. "Investigating the mechanism of the W-FdhAB from Desulfovibrio vulgaris Hildenborough". Paper presented in 12th ITQB NOVA PhD Students' Meeting, 2022.
  3. Rebelo Manuel, Rita; Oliveira, Ana Rita; Inês Antunes Cardoso Pereira. "Spectroscopic and structural studies of the W-dependent Formate dehydrogenase from Desulfovibrio vulgaris Hildenborough". Paper presented in 12th Molybdenum and Tungsten Enzymes Conference, 2021.
Journal article
  1. Mihai-Cristian Fera; Rita R. Manuel; Inês A.C. Pereira; Jose M. Abad; Antonio L. De Lacey; Marcos Pita. "Carbon nanotubes – PEI – Formate dehydrogenase nano-biointerface for the specific bioelectrochemical reduction of CO2 to formate". Carbon (2023): https://doi.org/10.1016/j.carbon.2023.118013.
    10.1016/j.carbon.2023.118013
  2. Erwin Lam; Melanie Miller; Stuart Linley; Rita R. Manuel; Inês A. C. Pereira; Erwin reisner. "Comproportionation of CO2 and Cellulose to Formate Using a Floating Semiconductor-Enzyme Photoreforming Catalyst". Angewandte Chemie International Edition 62 20 (2023): http://dx.doi.org/10.1002/anie.202215894.
    10.1002/anie.202215894
  3. Guilherme Vilela-Alves; Rita Rebelo Manuel; Ana Rita Oliveira; Inês Cardoso Pereira; Maria João Romão; Cristiano Mota. "Tracking W-Formate Dehydrogenase Structural Changes During Catalysis and Enzyme Reoxidation". International Journal of Molecular Sciences 24 1 (2022): 476-476. http://dx.doi.org/10.3390/ijms24010476.
    10.3390/ijms24010476
  4. Vivek M. Badiani; Carla Casadevall; Melanie Miller; Samuel J. Cobb; Rita R. Manuel; Inês A. C. Pereira; Erwin Reisner. "Engineering Electro- and Photocatalytic Carbon Materials for CO2 Reduction by Formate Dehydrogenase". Journal of the American Chemical Society (2022): https://doi.org/10.1021/jacs.2c04529.
    10.1021/jacs.2c04529
  5. Francesca D'Angelo; Elena Fernández-Fueyo; Pierre Simon Garcia; Helena Shomar; Martin Pelosse; Rita Rebelo Manuel; Ferhat Büke; et al. "Cellular assays identify barriers impeding iron-sulfur enzyme activity in a non-native prokaryotic host". eLife (2022): https://doi.org/10.7554/eLife.70936.
    10.7554/eLife.70936
Preprint
  1. Guilherme Vilela-Alves; Rita R. Manuel; Aldino Viegas; Philippe Carpentier; Frederic Biaso; Bruno Guigliarelli; Inês A. C. Pereira; Maria João Romão; Cristiano Mota. "Substrate-dependent oxidative inactivation of a W-dependent formate dehydrogenase involving selenocysteine displacement". 2024. https://doi.org/10.1101/2024.01.10.571421.
    10.1101/2024.01.10.571421
Thesis / Dissertation
  1. Rebelo Manuel, Rita. "Influence of Ferredoxin, Iron-Sulfur Carrier and Cobalamin Importer Overexpression on the Production of High-value Products by Escherichia coli". Master, Technische Universiteit Delft, 2019.