???global.info.a_carregar???
I am a senior research leader with a background in neurodegenerative diseases and over a decade of experience shaping and delivering research and funding strategy at scale. As Head of Research at Alzheimer’s Research UK, I oversaw a research portfolio of approximately £30 million annually, managing several funding schemes across discovery, translational and clinical research, and leading the departmental team. I was responsible for designing funding calls, establishing new partnerships, strengthening peer review processes, and aligning investment strategy with organisational priorities to maximise scientific impact. At the Francis Crick Institute, as Head of Translation Operations, I led the operational delivery of translational programmes supporting the Crick's research groups, coordinating cross-functional teams across science, legal, finance, and industry partnerships to accelerate the progression of discoveries toward application. Currently, as a member of the senior leadership team at MIA-Portugal, I support the delivery of the institute's science strategy during a critical growth phase, with responsibility for external funding, ethics governance, training and development, and human resources. I have implemented core administrative and operational systems and focused on strengthening MIA-Portugal’s competitiveness in national and European funding frameworks, enabling our growth and international positioning.
Identification

Personal identification

Full name
Rosa Maria Moreira Sancho

Citation names

  • Sancho, Rosa M

Author identifiers

Ciência ID
F711-54CF-C0ED

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Neurosciences

Languages

Language Speaking Reading Writing Listening Peer-review
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Portuguese (Mother tongue)
Education
Degree Classification
2009/07/30
Concluded
PhD in Pharmacology (Doctor of Philosophy)
University of London, United Kingdom
"Mechanistic pathways underlying familial Parkinson’s disease caused by leucine-rich repeat kinase 2 mutations" (THESIS/DISSERTATION)
2005/07/30
Concluded
BSc Hon Genetics (Bachelor)
Newcastle University, United Kingdom
Affiliation

Science

Category
Host institution
Employer
2023/10/01 - Current Science and Technology Management Universidade de Coimbra, Portugal
2023/06/21 - 2023/12/20 Science and Technology Management The Francis Crick Institute, United Kingdom
2012/07/01 - 2023/06/21 Science and Technology Management Alzheimer's Research UK, United Kingdom
2009/10/01 - 2012/06/30 Postdoc (Research) King's College London, United Kingdom
Projects

Grant

Designation Funders
2009/10/01 - 2012/06/30 MITOTARGET (Mitochondrial dysfunction in neurodegenerative diseases: towards new therapeutics)
Post-doc

Contract

Designation Funders
2023/09/01 - 2027/12/31 Multidisciplinary Institute of Ageing - Portugal
857524
Science and Technology Management Fellow
Universidade de Coimbra, Portugal
European Commission
Ongoing
2005/10/01 - 2009/09/30 Physiological and pathological role of the Parkinson’s disease protein LRRK2
Unknown
PhD Student Fellow
Outputs

Publications

Journal article
  1. Andreou, Melina; Choi, Narshil; Magenti, Jorge Gómez; Kohlhaas, Susan; Sancho, Rosa. "The dementia research career pipeline: Gender disparities in publication authorships and grant funding outcomes at different career stages". Health Open Research 4 (2022): 18. http://dx.doi.org/10.12688/amrcopenres.13072.1.
    10.12688/amrcopenres.13072.1
  2. Meyers, Emily A.; Amouyel, Philippe; Bovenkamp, Diane E.; Carrillo, Maria C.; De Buchy, Geraldine Drexel; Dumont, Magali; Fillit, Howard; et al. "Commentary: Global Alzheimer's disease and Alzheimer's disease related dementia research funding organizations support and engage the research community throughout the COVID-19 pandemic". Alzheimer's & Dementia 18 5 (2021): 1067-1070. http://dx.doi.org/10.1002/alz.12472.
    10.1002/alz.12472
  3. Snyder, Heather M.; Shineman, Diana W.; Friedman, Lauren G.; Hendrix, James A.; Khachaturian, Ara; Le Guillou, Ian; Pickett, James; et al. "Guidelines to improve animal study design and reproducibility for Alzheimer's disease and related dementias: For funders and researchers". Alzheimer's & Dementia 12 11 (2016): 1177-1185. http://dx.doi.org/10.1016/j.jalz.2016.07.001.
    10.1016/j.jalz.2016.07.001
  4. Mitchell, S.; Ridley, S.H.; Sancho, R.M.; Norton, M.. "The future of dementia risk reduction research: barriers and solutions". Journal of Public Health (2016): http://dx.doi.org/10.1093/pubmed/fdw103.
    10.1093/pubmed/fdw103
  5. Sancho, Rosa M.; Cox, Carla J.; Phipps, Laura E.; Ridley, Simon H.. "Alzheimer’s Research UK 2016 Conference report". Alzheimer's Research & Therapy 8 1 (2016): http://dx.doi.org/10.1186/s13195-016-0203-0.
    10.1186/s13195-016-0203-0
  6. Stoica, Radu; Paillusson, Sébastien; Gomez-Suaga, Patricia; Mitchell, Jacqueline C; Lau, Dawn HW; Gray, Emma H; Sancho, Rosa M; et al. "ALS / FTD -associated FUS activates GSK -3ß to disrupt the VAPBPTPIP 51 interaction and ER –mitochondria associations". EMBO reports 17 9 (2016): 1326-1342. http://dx.doi.org/10.15252/embr.201541726.
    10.15252/embr.201541726
  7. Sancho, Rosa M.; Cox, Carla J.; Ridley, Simon H.; Phipps, Laura E.; Karran, Eric. "Report from the Alzheimer’s Research UK Conference 2015". Alzheimer's Research & Therapy 7 1 (2015): http://dx.doi.org/10.1186/s13195-015-0138-x.
    10.1186/s13195-015-0138-x
  8. Godena, Vinay K.; Brookes-Hocking, Nicholas; Moller, Annekathrin; Shaw, Gary; Oswald, Matthew; Sancho, Rosa M.; Miller, Christopher C. J.; Whitworth, Alexander J.; De Vos, Kurt J.. "Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations". Nature Communications 5 1 (2014): http://dx.doi.org/10.1038/ncomms6245.
    10.1038/ncomms6245
  9. Stoica, Radu; De Vos, Kurt J.; Paillusson, Sébastien; Mueller, Sarah; Sancho, Rosa M.; Lau, Kwok-Fai; Vizcay-Barrena, Gema; et al. "ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43". Nature Communications 5 1 (2014): http://dx.doi.org/10.1038/ncomms4996.
    10.1038/ncomms4996
  10. Law, Bernard M.H.; Spain, Victoria A.; Leinster, Veronica H.L.; Chia, Ruth; Beilina, Alexandra; Cho, Hyun J.; Taymans, Jean-Marc; et al. "A Direct Interaction between Leucine-rich Repeat Kinase 2 and Specific ß-Tubulin Isoforms Regulates Tubulin Acetylation". Journal of Biological Chemistry 289 2 (2014): 895-908. http://dx.doi.org/10.1074/jbc.m113.507913.
    10.1074/jbc.m113.507913
  11. Sancho, Rosa M.; Law, Bernard M.H.; Harvey, Kirsten. "Mutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathways". Human Molecular Genetics 18 20 (2009): 3955-3968. http://dx.doi.org/10.1093/hmg/ddp337.
    10.1093/hmg/ddp337
Activities

Committee member

Activity description
Role
Institution / Organization
2023/01/01 - 2023/06/30 UK Ageing Research Funders Forum
Member
2021 - 2023 AMRC Equality, Diversity and Inclusion working group
Member
2021/01/01 - 2022/12/31 UK Government’s Bureaucracy Review Funders Panel
Member
2020 - 2022 AMRC Open Research Advisory Board
Member
2017 - 2022 NIHR Impact Advisory Board
Member
2016 - 2018 International Alzheimer’s Disease Research Funders Consortium
Coordinator
2014 - 2017 Dementia Research Funders Forum
Member

Conference scientific committee

Conference name Conference host
2015 - 2023 Alzheimer's Research UK Conference

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2023 Regular dementia research expert in UK press from 2015 to 2023