Zoé Enderlin Vaz da Silva (F319-E097-6823)

Curriculum Vitae

Zoé Enderlin Vaz da Silva

Highly organized and responsible researcher with excellent oral communication abilities, dedicated to advancing scientific knowledge with strong translational expertise applicable across various fields. Currently serving as an Assistant Professor at Egas Moniz School of Health and Science, she teaches at the MSc level and engages in research in forensic biology. Her previous experience as a Post-Doctoral Researcher at the Microbial Development Lab involved studying antibiotic resistance mechanisms in *C. difficile*, showcasing her capacity to bridge academic research with real-world applications. At GeneTagus CRISPR Technology, she honed her proficiency in gene editing, project management, and team leadership. Her role as a Metadata Analyst focused on the analysis of large datasets. Additionally, she gained foundational research experience as a Research Assistant in the Gastro-enterology Department at Lausanne University Hospital. She holds a PhD in Immunology and Virology from Instituto Gulbenkian de Ciência, specializing in the cell biology of viral infections. Her education includes participation in the Startup Research Program at ITQB-NOVA and NOVA-SBE, enhancing her understanding of innovation and entrepreneurship. She also completed a workshop on Emotional Intelligence Leadership and a course on "Os Cientistas e a Comunicação" at Universidade Nova de Lisboa, which focused on effective communication strategies for scientists. Committed to fostering innovation in multidisciplinary environments, she is eager to contribute to impactful projects that leverage her diverse background.

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Identification

Personal identification

Full name: Zoé Enderlin Vaz da Silva

Citation names

Vaz da Silva, Zoé

Author identifiers

Ciência ID: F319-E097-6823
ORCID iD: 0000-0002-9291-1930

Websites

https://www.linkedin.com/in/zoevazdasilva/ (Social media)
https://rzonemoretravelblog.wordpress.com (Blog)

Knowledge fields

Natural sciences - Biological Sciences - Microbiology
Natural sciences - Biological Sciences - Virology
Medical and Health Sciences - Basic Medicine - Immunology
Natural sciences - Biological Sciences - Genetics and Heredity
Natural sciences - Biological Sciences - Cell Biology
Natural sciences - Biological Sciences - Molecular Biology

Languages

Language	Speaking	Reading	Writing	Listening
Portuguese	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
French	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
English	Advanced (C1)	Advanced (C1)	Intermediate (B1)	Advanced (C1)
Italian	Intermediate (B1)	Intermediate (B1)	Beginner (A1)	Intermediate (B1)

Education

	Degree	Classification
2021/02/05 - 2021/05/14 Concluded	StartUp Research Program (Pós-Graduação) Major in Business, Innovation Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal Universidade Nova de Lisboa Nova School of Business and Economics, Portugal
2013/01 - 2018/02/27 Concluded	PhD in Integrative Biomedicine (Doutoramento) Major in Cell Biology, Virology Instituto Gulbenkian de Ciência, Portugal Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal "Influenza A virus modulates Regulators of Complement Activation" (THESIS/DISSERTATION)	n/a
2017/10/16 - 2017/10/20 Concluded	FLxFlow Course - Principles and applications of Flow cytometry (Curso de Especialização Tecnológica) Major in Técnicas de Citometria de Fluxo Instituto Gulbenkian de Ciência, Portugal Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal Fundação Champalimaud, Portugal
2013/10 - 2013/11 Concluded	Ciências de Animais de Laboratório FELASA Cat. B (Pós-Graduação) Major in Experimentação animal FELASA Cat. B Direcção-Geral de Alimentação e Veterinária, Portugal Instituto Gulbenkian de Ciência, Portugal Fundação Champalimaud, Portugal
2011 - 2012 Concluded	Master of Science in Medical Biology (Master) Major in Immunology and Cancer Université de Lausanne Faculté de biologie et médecine, Switzerland "Macrophage subsets in wound healing and colitis" (THESIS/DISSERTATION)	n/a
2007 - 2010 Concluded	Bachelor of Science in Biology (Bachelor) Université de Lausanne Faculté de biologie et médecine, Switzerland

Affiliation

Science

	Category Host institution	Employer
2022/03/01 - 2024/08/31	Postdoc (Research)	Egas Moniz Cooperativa de Ensino Superior CRL, Portugal

2019/05/06 - 2021/11/05	Postdoc (Research)	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2012/04 - 2012/12	Research Assistant (Research)	Centre Hospitalier Universitaire Vaudois, Switzerland
	Centre Hospitalier Universitaire Vaudois, Switzerland

Teaching in Higher Education

	Category Host institution	Employer
2024/09/01 - Current	Assistant Professor (University Teacher)	Egas Moniz Cooperativa de Ensino Superior CRL, Portugal
	Instituto Universitário Egas Moniz Centro de Investigação Interdisciplinar Egas Moniz, Portugal

Projects

Grant

	Designation	Funders
2013/01 - 2018/02/27	Influenza A virus modulates Regulators of Complement Activation SFRH/BD/52179/2013 PhD Student Fellow Instituto Gulbenkian de Ciência, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Outputs

Publications

Conference poster	Mendes, Aristides L.; Vaz da Silva, Zoé; Gonçalo Covas; Rita Ventura; Antunes Cordeiro, Tiago; Oleastro, Mónica; Monica Serrano; Filipe, Sérgio Raposo; Henriques, Adriano. "Identification of a novel MecA-like PBP in Clostridioides difficile involved in carbapenem resistance.". Paper presented in ClostPath 12, 2021. Nuno Brito Santos; Vaz da Silva, Zoé; Amorim, Maria Joao. "Complement Decay-Accelerating Factor is a modulator of influenza A virus lung immunopathology". Paper presented in CHS Virology e-Symposium, 2021. Alexandra S. Simões; Sónia. T Almeida; Carina Valente; Tiago Touret; João Lança; Ana R. Cruz; Sara Martins; et al. "A partnership between local government, primary-care center and a research institute to prevent COVID-19 outbreaks through active screening of civil servants in a Portuguese municipality". Paper presented in ESCMID Conference on Coronavirus Disease, 2020. Assistant staff Santos, NB; Vaz da Silva, Zoé; Amorim, Maria Joao. "Decay accelerating factor is a determinant of IAV virulence". Paper presented in Influenza Update Meetings, The University of Liverpool (online meeting), 2020. Santos, NB; Vaz da Silva, Zoé; Amorim, Maria Joao. "Influenza A virus-mediated alterations of sialylated host proteins". Paper presented in Young Scientists Retreat, 2019. Vaz da Silva, Zoé; Amorim, Maria Joao. "Modulation of DAF and CD59 by Influenza A virus". Paper presented in 27th Annual Meeting of the Society for Virology, 2017. Santos, NB; Vaz da Silva, Zoé; Amorim, Maria Joao. "Influenza A virus-mediated alterations of complement decay-accelerating factor". Paper presented in EMBO Workshop Proteostasis, 2017. Vaz da Silva, Zoé; Amorim, Maria Joao. "Deficiency in regulators of complement activation - DAF and CD59 - protects against influenza A virus infection". Paper presented in Keystone Conference - Innate immunity and determinants of microbial pathogenesis, 2015.
Journal article	Vaz da Silva, Zoé. "Complement Decay-Accelerating Factor is a modulator of influenza A virus lung immunopathology". PLOS Pathogens 17 7 (2021): e1009381-e1009381. http://dx.doi.org/10.1371/journal.ppat.1009381. 10.1371/journal.ppat.1009381 Enderlin Vaz Da Silva, Z.; Lehr, H.-A.; Velin, D.. "In vitro and in vivo repair activities of undifferentiated and classically and alternatively activated macrophages". Pathobiology 81 2 (2014): 86-93. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896731974&partnerID=MN8TOARS. 10.1159/000357306
Thesis / Dissertation	Vaz da Silva, Zoé. "Influenza A virus modulates Regulators of Complement Activation". PhD, Instituto Gulbenkian de Ciência, 2018. Vaz da Silva, Zoé. "Macrophage subsets in wound healing and colitis". Master, Université de Lausanne Faculté de biologie et médecine, 2012.
Working paper	Inês Morais; CANHÃO-PEREIRA, RUTE; Henriques, Bruna; Mariana Valente; Silveira, Célia M. ; Vaz da Silva, Zoé; Inês Mexia; et al. Corresponding author: Adriano O. Henriques. 2024. "Deletion of the sdaB gene reduces the susceptibility of Clostridioides difficile to vancomycin and increases biofilm formation".

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2016/06/02	Membrane Regulators of Complement Activation impact in influenza A virus pathogenicity	Sociedade Portuguesa de Imunologia Sociedade Portuguesa de Imunologia (Oeiras, Portugal)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2020/09 - 2021/10	Mecanismos de resistencia à vancomicina em C. difficile Co-supervisor	Microbiologia Médica (Master) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Event organisation

	Event name Type of event (Role)	Institution / Organization
2013/06 - 2014/05/28	Annual Meeting for Gulbenkian Students (AMeeGuS) 2014. This meeting allows for the sharing of scientific knowledge and dissemination of new ideas among PhD students from the Instituto Gulbenkian de Ciência and the Champalimaud Foundation. It required the ability to work as a team, and interaction with key speakers of international renown (T. Flatt from UNIL, Switzerland; HG. Ploegh from Boston Children’s Hospital, USA; O. Judson, John Simon Guggenheim Foundation; CP Heisenberg from IST, Austria) (2014/05/26 - 2014/05/28) Meeting (Member of the Organising Committee)	Instituto Gulbenkian de Ciência, Portugal

Event participation

	Activity description Type of event	Event name Institution / Organization
2020/05 - Current	Member of the ITQB NOVA COVID-19 Volunteer Working Group. COVID-19 PCR diagnosis in partnership with local government. Other	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2021/09/17 - 2021/09/17	Dia do Microrganismo Other	Dia do Microrganismo Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2021/04/22 - 2021/04/27	Conversas com cientistas: décadas de Ciência para dias de vacinas. Como foi possível desenvolver a vacina contra o Sars-CoV2 em tempo record.	Conversas com cientistas: décadas de Ciência para dias de vacinas Ciência Viva, Portugal
2017/07 - 2017/07	ImageJ/Fiji micro-workshop, from workflows to macros	Instituto Gulbenkian de Ciência, Portugal
2017/03/22 - 2017/03/25	27th Annual Meeting of the society for virology (GFV) Poster presentation: Modulation of DAF and CD59 by influenza A viruses Conference	27th Annual Meeting of the society for virology (GFV)
2015/04/19 - 2015/04/24	Keystone Symposia on Innate Immunity and Determinants of Microbial Pathogenesis and Mechanisms of Pro-Inflammatory Diseases Poster Presentation: Deficiency in regulators of complement activation - DAF and CD59 - protects against influenza A virus infection Symposium	Keystone Symposia on Innate Immunity and Determinants of Microbial Pathogenesis Keystone Symposia, United States

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2020/09/26 - 2020/10/06	Course on Bacterial Genetics and Recombinant DNA. Master degree course on Medical Microbiology, organized jointly by the Instituto de Higiene e de Medicina Tropical (IHMT), Faculdade de Ciências Médicas (FCM), Faculdade de Ciências e Tecnologia (FCT) and the Instituto de Tecnologia Quimica e Biológica (ITQB), of the Universidade Nova de Lisboa.	Microbiologia Médica (Mestrado)	Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2019/10 - 2019/10	Course on Bacterial Genetics and Recombinant DNA. Master degree course on Medical Microbiology, organized jointly by the Instituto de Higiene e de Medicina Tropical (IHMT), Faculdade de Ciências Médicas (FCM), Faculdade de Ciências e Tecnologia (FCT) and the Instituto de Tecnologia Quimica e Biológica (ITQB), of the Universidade Nova de Lisboa.	Microbiologia Médica (Mestrado)	Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal