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I obtained a degree in Biological Science in 2015 and a Master degree in Molecular and Cellular Biology in 2019 both awarded by the University of Pisa (Pisa, Italy). In 2020, I moved to Portugal in the context of the Erasmus+ project to study the role of alveolar macrophages in tuberculosis immunity which allowed me to generate preliminary data to successfully secure a Fundação para a Ciência e Tecnologia (FCT) PhD fellowship. I am currently working as PhD student at the Life and Health Sciences Research Institute (ICVS) investigating the immune response to Mycobacterium tuberculosis infection. In 2024, in the context of the work that I am developing in my PhD program, I was awarded with a European Society of Clinical Microbiology and Infectious Diseases (ESCMID) research grant (20000 €) to investigate the role of alveolar macrophages in resistance vs susceptibility to the intracellular pathogen Mycobacterium tuberculosis. Through my scientific career, I have published five articles in international peer-reviewed journals.
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Identification

Personal identification

Full name
Consuelo Micheli

Citation names

  • Micheli, Consuelo

Author identifiers

Ciência ID
F21D-99FE-E8CB
ORCID iD
0000-0002-6774-3541
Scopus Author Id
57213002780/57726280700

Telephones

Mobile phone
  • (+351) 253604844 (Professional)

Addresses

  • Immunobiology of Inflammatory and Infectious Diseases (i3Ds) Research Team, Life and Health Sciences Research Institute (ICVS): School of Medicine; University of Minho. Campos de Gualtar , 4710-057, Braga, Braga, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Immunology
  • Natural sciences - Biological Sciences - Microbiology

Languages

Language Speaking Reading Writing Listening Peer-review
Italian (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2)
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2021/01/01 - 2025
Ongoing
 Doutoramento em Ciências da Saúde (PhDCS) (Doutoramento)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2016/01/07 - 2019/09/23
Concluded
 Molecular and cellular biology (Laurea Magistrale)
Major in Prof. LUCIANA DENTE
Università degli Studi di Pisa, Italy
" Evaluation of genomic damage, cellular stress and cellular inflammation in peripheral blood lymphocytes from Systemic Erythematous Lupus and Undifferentiated Connective Tissue Disease patients." (THESIS/DISSERTATION)
 20/20
2009/10/01 - 2015/12/15
Concluded
 Biological Sciences (Laurea)
Major in Prof. LUCIANA DENTE
Università degli Studi di Pisa, Italy
"IRF5 polymorphisms in Systemic Lupus Erythematous;" (THESIS/DISSERTATION)
 17/20
Affiliation

Science

Category
Host institution 		Employer
2019/10/11 - 2020/09/30 Research Trainee (Research) Università degli Studi di Pisa Dipartimento di Biologia, Italy
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Others

Category
Host institution 		Employer
2021/01/01 - Current PhD Student Universidade do Minho, Portugal
Projects

Grant

Designation Funders
2024 - 2026 Unveiling tuberculosis susceptibility: the key role of alveolar macrophages
ESCMID research grant 2024
Principal investigator
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 European Society of Clinical Microbiology and Infectious Diseases
Ongoing

Contract

Designation Funders
2021/01/01 - 2024/12/31 Immunometabolic pathways underlying resistance or susceptibility to Mycobacterium tuberculosis infection
10.54499/2020.05976.BD
PhD Student Fellow
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2019/10/11 - 2020/09/30 Biology of alveolar macrophages following infection by Mycobacterium tuberculosis
1125/2019
Research Fellow
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Università degli Studi di Pisa Dipartimento di Biologia
Concluded
Outputs

Publications

Conference poster
  1. Micheli, Consuelo; Ana Rita Silva Ramalho Oliveira; Millán, Beatriz; Rodrigues, Fernando; Carvalho, Agostinho; Vilanova, Manuel; Castro, Gil; Torrado, Egídio. "Alveolar macrophages modulate BCG-Induced protection against Mycobacterium tuberculosis". Paper presented in SPI50 L Annual Meeting, 2025.
  2. Araújo, Marta; Micheli, Consuelo; Torrado, Egídio; Leal-Silvestre, RJ. "Sex Dimorphism in glycerophospholipid metabolism during Leishmania Infection". Paper presented in SPI2025: L Annual Meeting of the Portuguese Society for Immunology, 2025.
  3. Oliveira, Ana- Rita; Micheli, Consuelo; Millán, Beatriz; Araújo, Marta; Leal-Silvestre, RJ; Rodrigues, Fernando; Castro, Gil; Torrado, Egídio. "Macrophage differentiation and host variability shape tuberculosis outcomes". Paper presented in SPI2025: L Annual Meeting of the Portuguese Society for Immunology, 2025.
  4. Oliveira, Ana Rita; Micheli, Consuelo; Millán, Beatriz; Araújo, Marta; Silvestre, Ricardo; Rodrigues, Fernando; Castro, Gil; Torrado, Egídio. "Macrophage heterogeneity and host variability shape tuberculosis outcome". 2025.
  5. Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Rita Martins; Beatriz Costa; Torrado, Egídio; Leal-Silvestre, RJ. "Adipose Tissue and Immune Responses: Insights from Visceral Leishmaniasis". Paper presented in ICVS 2024 Retreat, 2024.
  6. Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Torrado, Egídio; Leal-Silvestre, RJ. "Exploring Lipid Influence on Macrophages during Leishmania Infection". Paper presented in ICVS 2024 Retreat, 2024.
  7. Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Torrado, Egídio; Leal-Silvestre, RJ. "Unravelling the Influence of Lipid Accumulation in Macrophages during Leishmania Infection". Paper presented in 1st Symposium on Lipids and Cell Plasticity, 2024.
  8. Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Rita Martins; Beatriz Costa; Torrado, Egídio; Leal-Silvestre, RJ. "Uncovering the role of adipose tissue in the immune response to visceral leishmaniasis". Paper presented in 1st Symposium on Lipids and Cell Plasticity, 2024.
  9. Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Rita Martins; Torrado, Egídio; Leal-Silvestre, RJ. "Analysis of the Role of Adipose Tissue in the Immune Response to Visceral Leishmaniasis". Paper presented in VII iBiMED symposium, 2024.
  10. Araújo, Marta; Mendes-Frias, Ana ; Micheli, Consuelo; Torrado, Egídio; Silvestre, Ricardo. "Deciphering the Role of Lipid Accumulation in Macrophages during Leishmania Infection". Paper presented in Pathogen immunity and signaling - EMBO Workshop, 2024.
  11. Micheli, Consuelo; Mendes-Frias, Ana ; Araújo, Marta; Rodrigues, Fernando; Carvalho, Agostinho; Vilanova, Manuel; Silvestre, Ricardo; Castro, António Gil; Torrado, Egídio. "The key role of alveolar macrophages in shaping the CD4+ T cell activation and control of M. tuberculosis infection". Paper presented in Pathogen immunity and signaling EMBO Meeting, San servolo, Veneza, 8th-12th, 2024.
  12. Mendes-Frias, Ana; Vieira, Maria C.; Araújo, Marta; Micheli, Consuelo; Duarte, Iola F.; Gaifem, Joana; Torrado, Egídio; et al. "Branched-Chain Amino Acids in Ulcerative Colitis: friend or foe?". Paper presented in XLIX Annual Meeting of the Portuguese Society for Immunology,, 2024.
  13. Micheli, Consuelo; Mendes-Frias, Ana ; Araújo, Marta; Rodrigues, Fernando; Carvalho, Agostinho; Vilanova, Manuel; Silvestre, Ricardo; Torrado, Egídio. "The impact of alveolar macrophages in the CD4+ T cell activation and control of Mycobacterium tuberculosis infection". Paper presented in EMBO Young Scientists' Forum, 2023.
  14. Mendes-Frias, Ana ; Vieira, Maria C.; Araújo, Marta; Micheli, Consuelo; Gaifem, Joana; Torrado, Egídio; Lopes, Luís; Silvestre, Ricardo. "Unraveling the dynamic effect of branched-chain amino acids in the gut: the influence of sex". Paper presented in EMBO Young Scientists' Forum, 2023.
  15. Mendes-Frias, Ana; Vieira, Maria C.; Araújo, Marta; Micheli, Consuelo; Gaifem, Joana; Torrado, Egídio; Lopes, Luís; Silveste, Ricardo. "Unraveling the dynamic effect of branched-chain amino acids in the gut". Paper presented in Retreat for postgraduate students at the School of Medicine, 2023.
  16. Micheli, Consuelo; Mendes-Frias, Ana ; Araújo, Marta; Rodrigues, Fernando; Carvalho, Agostinho; Vilanova, Manuel; Silvestre, Ricardo; Castro, Gil; Torrado, Egídio. "Delayed migration of alveolar macrophages to the lung parenchyma hampers CD4+ T cells activation and prevents control of Mycobacterium tuberculosis infection". Paper presented in XLVIII SPI Annual Meeting 2023, 2023.
Journal article
  1. Chiaramonte, Anna; Testi, Serena; Pelosini, Caterina; Micheli, Consuelo; Falaschi, Aurora; Ceccarini, Giovanni; Santini, Ferruccio; Scarpato, Roberto. "Oxidative and DNA damage in obese patients undergoing bariatric surgery: A one-year follow-up study". Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 827 (2023): 111827. http://dx.doi.org/10.1016/j.mrfmmm.2023.111827.
    10.1016/j.mrfmmm.2023.111827
  2. Scarpato, Roberto; Colosimo, Valentina; Chiaramonte, Anna; Di Bello, Domenica; Esposti, Veronica; Falaschi, Aurora; Ghirri, Paolo; Micheli, Consuelo; Testi, Serena. "High level of ¿H2AX phosphorylation in the cord-blood cells of large-for-gestational-age (LGA) newborns". Mutation Research/Genetic Toxicology and Environmental Mutagenesis 881 (2022): 503526. http://dx.doi.org/10.1016/j.mrgentox.2022.503526.
    10.1016/j.mrgentox.2022.503526
  3. Ferreira, Catarina M.; Micheli, Consuelo; Barreira-Silva, Palmira; Barbosa, Ana Margarida; Resende, Mariana; Vilanova, Manuel; Silvestre, Ricardo; et al. "IL-10 Overexpression After BCG Vaccination Does Not Impair Control of Mycobacterium tuberculosis Infection". Frontiers in Immunology 13 (2022): http://dx.doi.org/10.3389/fimmu.2022.946181.
    10.3389/fimmu.2022.946181
  4. Micheli, Consuelo; Parma, Alice; Tani, Chiara; Di Bello, Domenica; Falaschi, Aurora; Chiaramonte, Anna; Testi, Serena; Mosca, Marta; Scarpato, Roberto. "UCTD and SLE patients show increased levels of oxidative and DNA damage together with an altered kinetics of DSB repair". Mutagenesis (2021): http://dx.doi.org/10.1093/mutage/geab036.
    10.1093/mutage/geab036
  5. Scarpato, Roberto; Testi, Serena; Colosimo, Valentina; Garcia Crespo, Carlos; Micheli, Consuelo; Azzarà, Alessia; Tozzi, Maria Giulia; Ghirri, Paolo. "Role of oxidative stress, genome damage and DNA methylation as determinants of pathological conditions in the newborn: an overview from conception to early neonatal stage". Mutation Research/Reviews in Mutation Research 783 (2020): 108295. http://dx.doi.org/10.1016/j.mrrev.2019.108295.
    10.1016/j.mrrev.2019.108295
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025/02/10 Unveiling tuberculosis susceptibility: the key role of alveolar macrophages ICVS Student Seminar
ICVS (Braga, Portugal)
2024/07/05 The key role of alveolar macrophages in tuberculosis susceptibility ICVS student retreat
ICVS (Braga, Portugal)
2024/04/19 Unveiling tuberculosis susceptibility: the key role of alveolar macrophages XLIX Annual Meeting of the Portuguese Society for Immunology
SPI (Porto, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2025/03/17 - 2025/06/17 Impacto do ambiente inflamatório pulmonar na resposta imunitaria a infeção por Mycobacterium tuberculosis
Co-supervisor
Universidade do Minho Escola de Ciências da Saúde, Portugal
2025/02/01 - 2025/03/15 IL-1R blockade: impact on alveolar macrophage migration and T cell activation during Mycobacterium tuberculosis infection
Co-supervisor
Universidade do Minho Escola de Ciências da Saúde, Portugal
2024/12/07 - 2025/03/07 Resposta dos macrófagos à infeção por Mycobacterium tuberculosis em hospedeiros suscetíveis e resistentes
Co-supervisor
Universidade do Minho Escola de Ciências da Saúde, Portugal
2024/12/01 - 2025/01/11 Characterizing the response of Bone Marrow Derived Macrophages in the context of tuberculosis
Co-supervisor
Universidade do Minho Escola de Ciências da Saúde, Portugal
2024/12/07 - 2025/01/07 Unravelling the role of pentraxin 3 in immune response and control of Mycobacterium tuberculosis infection in the murine model of tuberculosis
Co-supervisor
Universidade do Minho Escola de Ciências da Saúde, Portugal
2024/10/02 - 2024/12/02 Unravelling the Role of Alveolar Macrophages in the Control of Mycobacterium tuberculosis by Susceptible and Resistant Hosts
Co-supervisor
Universidade do Minho Escola de Ciências da Saúde, Portugal
2024/05/10 - 2024/06/27 O papel dos macrofagos alveolares no controlo de infeçoes por Mycobacterium tuberculosis em hospedeiros suscetiveis e resistentes.
Co-supervisor
Universidade do Minho Departamento de Biologia, Portugal
2024/04/01 - 2024/06/10 Unravelling the Role of Alveolar Macrophages in the Control of Mycobacterium tuberculosis by Susceptible and Resistant Hosts
Co-supervisor
Universidade do Minho Escola de Ciências da Saúde, Portugal
2024/04/01 - 2024/06/10 Alveolar macrophages as roadblocks in CD4 T cells activation following Mycobacterium tuberculosis infection
Co-supervisor
Universidade do Minho Escola de Ciências da Saúde, Portugal
2024/04/01 - 2024/06/10 Role of alveolar macrophages in the establishment of protective recall responses to Mycobacterium tuberculosis infection
Co-supervisor
Universidade do Minho Escola de Ciências da Saúde, Portugal
2024/02/01 - 2024/03/15 The role of GM-CSF in Mycobacterium tuberculosis infection
Co-supervisor
Universidade do Minho Escola de Ciências da Saúde, Portugal
2024/02/01 - 2024/03/15 Impact of the depletion of alveolar macrophages in Mycobacterium tuberculosis infection
Co-supervisor
Universidade do Minho Escola de Ciências da Saúde, Portugal
2023/04 - 2023/10 Role of alveolar macrophages in the control of Mycobacterium tuberculosis infection
Co-supervisor
Università degli Studi di Bologna Dipartimento di Scienze Biologiche Geologiche ed Ambientali, Italy
2023/04 - 2023/07 Evaluation of lipid droplets and lipid mediators in macrophages during Mycobacterium tuberculosis infection
Co-supervisor
Universidade do Minho Departamento de Biologia, Portugal
2023/04 - 2023/07 Papel de macrófagos alveolares no controlo da infeção por Mycobacterium tuberculosis
Co-supervisor
Universidade do Minho Departamento de Biologia, Portugal
2023/03/01 - 2023/04/15 Development of a quantitative approach to assess the location of alveolar macrophages within the lungs of Mycobacterium tuberculosis infected hosts
Co-supervisor
Universidade do Minho Escola de Ciências da Saúde, Portugal
2022/10 - 2022/12 The role of IL-23 and microbiome in immune response to Mycobacterium tuberculosis
Co-supervisor
Universidade do Minho Escola de Ciências da Saúde, Portugal
2022/04 - 2022/07 O papel de macrófagos no controlo de Mycobacterium tuberculosis em hospedeiros suscetíveis e resistentes à infeção
Co-supervisor
Universidade do Minho Departamento de Biologia, Portugal
2022/04 - 2022/07 Resposta de macrófagos de hospedeiros suscetíveis e resistentes à infeção por Mycobacterium tuberculosis
Co-supervisor
Universidade do Minho Departamento de Biologia, Portugal
Distinctions

Award

2024 EMBO Travel Grant
2019 Best student Cum Laude Award
Università degli Studi di Pisa, Italy