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I obtained a degree in Biological Science in 2015 and a Master degree in Molecular and Cellular Biology in 2019 both awarded by the University of Pisa (Pisa, Italy). In 2020, I moved to Portugal in the context of the Erasmus+ project to study the role of alveolar macrophages in tuberculosis immunity which allowed me to generate preliminary data to successfully secure a Fundação para a Ciência e Tecnologia (FCT) PhD fellowship. I am currently working as PhD student at the Life and Health Sciences Research Institute (ICVS) investigating the immune response to Mycobacterium tuberculosis infection. In 2024, in the context of the work that I am developing in my PhD program, I was awarded with a European Society of Clinical Microbiology and Infectious Diseases (ESCMID) research grant (20000 €) to investigate the role of alveolar macrophages in resistance vs susceptibility to the intracellular pathogen Mycobacterium tuberculosis. Through my scientific career, I have published five articles in international peer-reviewed journals.
Identification

Personal identification

Full name
Consuelo Micheli

Citation names

  • Micheli, Consuelo

Author identifiers

Ciência ID
F21D-99FE-E8CB
ORCID iD
0000-0002-6774-3541
Scopus Author Id
57213002780/57726280700

Telephones

Mobile phone
  • (+351) 253604844 (Professional)

Addresses

  • Immunobiology of Inflammatory and Infectious Diseases (i3Ds) Research Team, Life and Health Sciences Research Institute (ICVS): School of Medicine; University of Minho. Campos de Gualtar , 4710-057, Braga, Braga, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Immunology
  • Natural sciences - Biological Sciences - Microbiology

Languages

Language Speaking Reading Writing Listening Peer-review
Italian (Mother tongue)
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Intermediate (B1)
French Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2)
Portuguese Intermediate (B1) Upper intermediate (B2) Intermediate (B1) Upper intermediate (B2) Intermediate (B1)
Education
Degree Classification
2021/01/01 - 2025
Ongoing
Doutoramento em Ciências da Saúde (PhDCS) (Doutoramento)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2016/01/07 - 2019/09/23
Concluded
Molecular and cellular biology (Laurea Magistrale)
Major in Prof. LUCIANA DENTE
Università degli Studi di Pisa, Italy
" Evaluation of genomic damage, cellular stress and cellular inflammation in peripheral blood lymphocytes from Systemic Erythematous Lupus and Undifferentiated Connective Tissue Disease patients." (THESIS/DISSERTATION)
20/20
2009/10/01 - 2015/12/15
Concluded
Biological Sciences (Laurea)
Major in Prof. LUCIANA DENTE
Università degli Studi di Pisa, Italy
"IRF5 polymorphisms in Systemic Lupus Erythematous;" (THESIS/DISSERTATION)
17/20
Affiliation

Science

Category
Host institution
Employer
2019/10/11 - 2020/09/30 Research Trainee (Research) Università degli Studi di Pisa Dipartimento di Biologia, Italy
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Others

Category
Host institution
Employer
2021/01/01 - Current PhD Student Universidade do Minho, Portugal
Projects

Grant

Designation Funders
2024 - 2026 Unveiling tuberculosis susceptibility: the key role of alveolar macrophages
ESCMID research grant 2024
Principal investigator
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
European Society of Clinical Microbiology and Infectious Diseases
Ongoing

Contract

Designation Funders
2021/01/01 - Current Immunometabolic pathways underlying resistance or susceptibility to Mycobacterium tuberculosis infection
2020.05976.BD
PhD Student Fellow
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2019/10/11 - 2020/09/30 Biology of alveolar macrophages following infection by Mycobacterium tuberculosis
1125/2019
Research Fellow
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Università degli Studi di Pisa Dipartimento di Biologia
Ongoing
Outputs

Publications

Journal article
  1. Chiaramonte, Anna; Testi, Serena; Pelosini, Caterina; Micheli, Consuelo; Falaschi, Aurora; Ceccarini, Giovanni; Santini, Ferruccio; Scarpato, Roberto. "Oxidative and DNA damage in obese patients undergoing bariatric surgery: A one-year follow-up study". Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 827 (2023): 111827. http://dx.doi.org/10.1016/j.mrfmmm.2023.111827.
    10.1016/j.mrfmmm.2023.111827
  2. Scarpato, Roberto; Colosimo, Valentina; Chiaramonte, Anna; Di Bello, Domenica; Esposti, Veronica; Falaschi, Aurora; Ghirri, Paolo; Micheli, Consuelo; Testi, Serena. "High level of ¿H2AX phosphorylation in the cord-blood cells of large-for-gestational-age (LGA) newborns". Mutation Research/Genetic Toxicology and Environmental Mutagenesis 881 (2022): 503526. http://dx.doi.org/10.1016/j.mrgentox.2022.503526.
    10.1016/j.mrgentox.2022.503526
  3. Ferreira, Catarina M.; Micheli, Consuelo; Barreira-Silva, Palmira; Barbosa, Ana Margarida; Resende, Mariana; Vilanova, Manuel; Silvestre, Ricardo; et al. "IL-10 Overexpression After BCG Vaccination Does Not Impair Control of Mycobacterium tuberculosis Infection". Frontiers in Immunology 13 (2022): http://dx.doi.org/10.3389/fimmu.2022.946181.
    10.3389/fimmu.2022.946181
  4. Micheli, Consuelo; Parma, Alice; Tani, Chiara; Di Bello, Domenica; Falaschi, Aurora; Chiaramonte, Anna; Testi, Serena; Mosca, Marta; Scarpato, Roberto. "UCTD and SLE patients show increased levels of oxidative and DNA damage together with an altered kinetics of DSB repair". Mutagenesis (2021): http://dx.doi.org/10.1093/mutage/geab036.
    10.1093/mutage/geab036
  5. Scarpato, Roberto; Testi, Serena; Colosimo, Valentina; Garcia Crespo, Carlos; Micheli, Consuelo; Azzarà, Alessia; Tozzi, Maria Giulia; Ghirri, Paolo. "Role of oxidative stress, genome damage and DNA methylation as determinants of pathological conditions in the newborn: an overview from conception to early neonatal stage". Mutation Research/Reviews in Mutation Research 783 (2020): 108295. http://dx.doi.org/10.1016/j.mrrev.2019.108295.
    10.1016/j.mrrev.2019.108295
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/10/12 The impact of alveolar macrophages in the CD4+ T cell activation and control of Mycobacterium tuberculosis infection EMBO Young Scientists' Forum
(Lisbon, Portugal)
2023/03/29 Delayed migration of alveolar macrophages to the lung parenchyma hampers CD4+ T cells activation and prevents control of Mycobacterium tuberculosis infection XLVIII SPI Annual Meeting 2023
SPI (Aveiro, Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2023/04 - 2023/10 Role of alveolar macrophages in the control of Mycobacterium tuberculosis infection
Co-supervisor
Università degli Studi di Bologna Dipartimento di Scienze Biologiche Geologiche ed Ambientali, Italy
2023/04 - 2023/07 Evaluation of lipid droplets and lipid mediators in macrophages during Mycobacterium tuberculosis infection
Co-supervisor
Universidade do Minho Departamento de Biologia, Portugal
2023/04 - 2023/07 Papel de macrófagos alveolares no controlo da infeção por Mycobacterium tuberculosis
Co-supervisor
Universidade do Minho Departamento de Biologia, Portugal
2022/04 - 2022/07 O papel de macrófagos no controlo de Mycobacterium tuberculosis em hospedeiros suscetíveis e resistentes à infeção
Co-supervisor
Universidade do Minho Departamento de Biologia, Portugal
2022/04 - 2022/07 Resposta de macrófagos de hospedeiros suscetíveis e resistentes à infeção por Mycobacterium tuberculosis
Co-supervisor
Universidade do Minho Departamento de Biologia, Portugal
Distinctions

Award

2019 Best student Cum Laude Award
Università degli Studi di Pisa, Italy