???global.info.a_carregar???
Ricardo Bastos Leite is a molecular biologist and genomics scientist with a multidisciplinary background spanning host–pathogen interaction, parasitology, molecular and cellular biology, genomics, bioinformatics and research data management. He holds a PhD in Biological Sciences – Cellular and Molecular Biology from the University of Algarve, following earlier training in Biochemistry and a Master’s degree in Aquaculture and Fisheries, and later completed postdoctoral work in computational genomics at Instituto Gulbenkian de Ciência. His advanced training also includes the Biology of Parasitism course at the Marine Biological Laboratory, Woods Hole, as well as specialised training in data stewardship, precision medicine and clinical genetics/genomics. Over the course of his career, he has combined fundamental and applied research in parasite biology, marine and environmental genomics, infectious diseases, biotechnology and, more recently, genomics-driven translational and clinical settings. He served as Head of the Genomics Unit at Instituto Gulbenkian de Ciência (2019–2024) and as President of the General Assembly Board of BIP4DAB / BioData.pt (2023–2024). His work has included NGS, transcriptomics, single-cell and spatially oriented approaches, comparative and functional genomics, metagenomics, and the development of reproducible bioinformatic workflows and data infrastructures. His publication record includes contributions in parasitology, antiprotozoal compounds, host–parasite interactions, marine genomics, cyanobacteria, COVID-19 genomics and single-cell analysis of rodent blood-stage Plasmodium. He is also co-inventor on patents related to industrial biotechnology and endoperoxide antiparasitic compounds. In addition to research, he has been active in teaching, supervision, scientific networking and infrastructure development, and currently coordinates a molecular pathology laboratory, reinforcing his profile at the interface of genomics, data analysis and applied biomedical implementation.
Read full resume ↓
Identification

Personal identification

Full name
Ricardo Bastos Leite

Citation names

  • Leite, Ricardo B

Author identifiers

Ciência ID
F115-256E-C84D
ORCID iD
0000-0002-9622-3895
Google Scholar ID
zrpuoYwAAAAJ

Email addresses

  • ricardo@rbleite.com (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Spanish; Castilian Advanced (C1) Advanced (C1) Upper intermediate (B2) Proficiency (C2) Upper intermediate (B2)
French Upper intermediate (B2) Advanced (C1) Upper intermediate (B2) Upper intermediate (B2) Intermediate (B1)
Education
Degree Classification
2012
Concluded
 Ciências Biológicas (Doutoramento)
Major in Biologia Celular e Molecular
Universidade do Algarve, Portugal
2012
Concluded
 Bioquímica (Doutoramento)
Major in Especialidade: Biologia Celular e Molecular
Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
"EXPLORING AN UNCOMMON HOST-PARASITE INTERACTION TO UNVEIL THE UNIQUENESS OF PERKINSUS SP AS A MODEL ORGANISM" (THESIS/DISSERTATION)
2005
Concluded
 Master Acuicultura y pescas (Master Universitario)
Universidad de Cádiz Facultad de Ciencias del Mar y Ambientales, Spain
2002
Concluded
 Bioquímica (Licenciatura)
Universidade do Algarve, Portugal
Affiliation

Science

Category
Host institution 		Employer
2019/01/01 - 2024/12/31 Researcher (Research) Instituto Gulbenkian de Ciência, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2018/04/01 - 2019/03/31 Invited Adjunct Teacher (Polytechnic Teacher) Instituto Politécnico de Setúbal, Portugal
Instituto Politécnico de Setúbal Escola Superior de Tecnologia do Barreiro, Portugal
2014 - 2015 Invited Associate Professor (University Teacher) Universidade do Algarve, Portugal
Universidade do Algarve - Campus de Gambelas, Portugal

Other Careers

Category
Host institution 		Employer
2025/01/01 - Current Coordenador (Técnico de Diagnóstico e Terapêutica - Técnico de Anatomia Patológica, Citológica e Tanatológica) Unidade Local de Saúde de Almada-Seixal, Portugal
Unidade Local de Saúde de Almada-Seixal, Portugal
Projects

Grant

Designation Funders
2023/03/12 - 2024/09/11 Evolution of extended lifespan in S. cerevisiae
2022.07846.PTDC
10.54499/2022.07846.PTDC
Co-Principal Investigator (Co-PI)
Instituto Gulbenkian de Ciência, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2020/01/01 - 2023/02/21 “Single Cell Hub”: Tornar o invisível, visível, na saúde e na doença
LISBOA-01-0246-FEDER-000037
Principal investigator
Fundação Calouste Gulbenkian, Portugal

Instituto Gulbenkian de Ciência, Portugal
Concluded
2020/04/01 - 2020/10/01 Predicting SARS-CoV-2 susceptibility by tracking the genetic variability of the ACE2 receptor
613747728
Principal investigator
Fundação Calouste Gulbenkian, Portugal

Instituto Gulbenkian de Ciência, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/07 - 2014/06 Intelligent Cell Surfaces (ICS)
Provided by PTCRIS: 123624
123624
 Fundação para a Ciência e a Tecnologia, I.P.
2011/07 - 2014/06 AQUATOX - Assessment of mineralogenic toxicity of aquatic pollutants
112992
Provided by PTCRIS: 112992
 Fundação para a Ciência e a Tecnologia, I.P.
2010/01 - 2013/07 Development and characterization of zebrafish stem cells: implications for transgenesis - FishCell
Provided by PTCRIS: 105313
105313
 Fundação para a Ciência e a Tecnologia, I.P.
2008/07 - 2011/10 Development of tools to analyse sperm quality in fish: implications for cryobanking- CRYOSPERM
64533
Provided by PTCRIS: 64533
 Fundação para a Ciência e a Tecnologia, I.P.
2007/08 - 2010/07 Characterization of isoprenoids biosynthesis and determination of potential therapeutic targets
72083
Provided by PTCRIS: 72083
 Fundação para a Ciência e a Tecnologia, I.P.
2005/06 - 2008/05 Characterisation of the folate and purine metabolism in the protozoan parasite Perkinsus atlanticus: identification of genes involved in these pathways and potential therapeuthic targets
57982
Provided by PTCRIS: 57982
 Fundação para a Ciência e a Tecnologia, I.P.

Contract

Designation Funders
2024/09/10 - Current GLIM-BioData – Gateway for Living Data Management
RE-C05-i08
RI/00138/2024
BioData.pt, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2023/09/01 - Current Life Sciences for a Healthy and Sustainable Future
LA/P/0087/2020
10.54499/LA/P/0087/2020
Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal

Universidade Nova de Lisboa Molecular Structural and Cellular Microbiology, Portugal

Universidade Nova de Lisboa, Portugal

Instituto Gulbenkian de Ciência, Portugal

Instituto de Biologia Experimental e Tecnológica, Portugal

Universidade de Lisboa Centro de Estudos Comparatistas, Portugal

Universidade de Trás-os-Montes e Alto Douro Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas, Portugal

BioResources 4 Sustainability, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2023/09/01 - Current FCT LA LS4Future: Life Sciences for a Healthy and Sustainable Future (team member)
LA/P/0087/2020
10.54499/LA/P/0087/2020
Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Portugal

GREEN-IT, Portugal

Universidade de Trás-os-Montes e Alto Douro Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas, Portugal

Instituto Gulbenkian de Ciência, Portugal

Instituto de Biologia Experimental e Tecnológica, Portugal

Universidade de Lisboa Centro de Estudos Comparatistas, Portugal

Universidade Nova de Lisboa, Portugal

Universidade Nova de Lisboa Molecular Structural and Cellular Microbiology, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2021/07/01 - 2024/06/30 Kits de ferramentas genéticas e a evolução molecular do comportamento social: os peixes teleósteos como modelo de estudo comparativo
PTDC/BIA-COM/3068/2020
Fundação Calouste Gulbenkian, Portugal

Instituto Gulbenkian de Ciência, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2016/06/01 - 2019/05/31 Controlo da perkinsose em amêijoas usando endoperóxidos análogos de Artemisinina
PTDC/MAR-BIO/4132/2014
Fundação Calouste Gulbenkian, Portugal

Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/07/01 - 2015/03/31 Sensores inteligentes para monitorizar células biológicas
EuroBioSAS/0001/2010
Universidade do Algarve, Portugal

Universidade do Algarve Centro de Electronica Optoelectrônica e Telecomunicacoes, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2012/02/01 - 2015/01/31 Loss of robustness as a drug targeting principle for drug repositioning
PTDC/EBB-BIO/119006/2010
Fundação Calouste Gulbenkian, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2005/06/01 - 2008/05/31 Caracterização dos metabolismos do ácido fólico e das purinas no protozoário parasita Perkinsus atlanticus: identificação dos genes envolvidos na sua biossintese e potenciais alvos terapêuticos
POCI/CVT/57982/2004
 Fundação para a Ciência e a Tecnologia
Concluded
2000/10/02 - 2004/10/01 Transistores de efeito de campo para medir actividade eléctrica de células individuais em cultura.
POCTI/FIS/34668/2000
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Leite, Ricardo B. "Biotecnologia e síntese química ao serviço dos mariscadores". In A europa e o Mar: Inovação e investigação cientifica em Portugal. Faro, Portugal, 2016.
    Published
  2. Leite, Ricardo B. "Biodiversidade azul em Portugal". In Mar Português- conhecimento, valorização e desenvolvimento. Faro, Portugal: Universidade do Algarve, 2012.
    Published
  3. B., Ricardo; Afonso, Ricardo; Leonor, M.. "Herbicides and Protozoan Parasite Growth Control: Implications for New Drug Development". In Herbicides, Theory and Applications, 567-580. Croatia: InTech, 2011.
    Published • 10.5772/13345
  4. Cancela, M. Leonor; Bargelloni, Luca; Boudry, Pierre; Boulo, Viviane; Dias, Jorge; Huvet, Arnaud; Laizé, Vincent; et al. "Genomic Approaches in Aquaculture and Fisheries". In Introduction to Marine Genomics, 213-286. Springer Netherlands, 2010.
    Published • 10.1007/978-90-481-8639-6_7
  5. Leite, Ricardo B. "Bivalves-perkinsus spp interactions". In Workshop for the analysis of the impact of perkinsosis to the European Shellfish industry. Vigo: Xunta de Galicia, 2008.
    Published
  6. Leite, Ricardo B. "Host parasites of the genus Perkinsus". In Workshop for the analysis of the impact of Perkinsosis to the European Shellfish Industry. Vigo, Spain: Centro de Investigacións Mariñas, Consellería de Pesca e Asuntos Marítimos da Xunta de Galicia, 2008.
    Published
Conference paper
  1. Leite, Ricardo B. "15. Can post-thaw sperm quality affect progeny from European seabass?". 2012.
    10.1016/j.cryobiol.2012.07.016
  2. Gomes, H.L.; Leite, R.B.; Afonso, R.; Stallinga, P.; Cancela, M.L.. "A microelectrode impedance method to measure interaction of cells". 2004.
    10.1109/icsens.2004.1426344
Conference poster
  1. OLIVEIRA, JORGE; Ventura-Costa, Carolina; Faria, Daniel; Barros, Pedro; Chaves, Inês; Antunes, Célia M.; Paixão, Tiago; et al. Corresponding author: OLIVEIRA, JORGE. "Setting the ground for Biological Data Management and Interoperability in Portugal". Paper presented in ELIXIR All Hands, Amsterdam, 2022.
    10.7490/f1000research.1118983.1
  2. Brandão, Ana S.; Bensimon-Brito, Anabela; Mesquita, Duarte; Leite, Ricardo B; Farinho, Ana; Valério, Fábio; Jacinto, António. "Regulation of osteoblast dedifferentiation during adult zebrafish caudal fin regeneration". Paper presented in Molecular and Cellular Basis of Regeneration and Tissue Repair, Guixols, Spain, 2014.
  3. Silva, Iris AL; Leite, Ricardo B; Cancela, M. Leonor; Conceição, Natércia. "TFIIH Is Remarkably Conserved Between Zebrafish And Human". Paper presented in V Clinical Biochemistry Workshop, Coimbra, Portugal, 27 January, 2012, 2012.
Journal article
  1. André C. Pereira; Francisco Cortez; Guilherme Chaves; Enrico Nanetti; Ricardo B. Leite; Madalena Caria Mendes; Inês Oliveira; et al. "Thirteen metagenome-assembled genomes of Paraglaciecola chathamensis associated with the farmed red seaweeds Porphyra dioica and Porphyra umbilicalis". Microbiology Resource Announcements (2026): http://dx.doi.org/10.1128/mra.01496-25.
    10.1128/mra.01496-25
  2. Francisco Cortez; Enrico Nanetti; Guilherme Chaves; André C. Pereira; Madalena C. Mendes; Inês Oliveira; Daniela Leuzzi; et al. "Prokaryotic community structure and auxin biosynthesis in early developmental stages of farmed Atlantic Nori (Porphyra spp.)". Frontiers in Microbiology (2026): http://dx.doi.org/10.3389/fmicb.2025.1750184.
    10.3389/fmicb.2025.1750184
  3. Pedro S. de Oliveira; Inês Sofia Vala; Filipe Rocha; Ricardo B. Leite; Pedro Faísca; Paula de Oliveira; Filomena Pina; et al. "Enhancing buccal mucosa graft healing in urethroplasty: unraveling the molecular effects of two distinct therapies: low-dose radiation and low-intensity shockwave therapy". Journal of Translational Medicine (2025): http://dx.doi.org/10.1186/s12967-025-07532-w.
    10.1186/s12967-025-07532-w
  4. Mariana Girão; José Murillo-Alba; Jesús Martín; Ignacio Pérez-Victoria; Ricardo B. Leite; Ralph Urbatzka; Pedro N. Leão; Maria F. Carvalho; Fernando Reyes. "Cellulamides: A New Family of Marine-Sourced Linear Peptides from the Underexplored Cellulosimicrobium Genus". Marine Drugs (2024): https://doi.org/10.3390/md22060268.
    10.3390/md22060268
  5. Jentho, Elisa; Sousa, António G.G.; Ramos, Susana; Ademolue, Temitope W.; Sobral, João; Costa, João; Brito, Denise; et al. "Single-cell RNA sequencing and analysis of rodent blood stage Plasmodium". STAR Protocols 4 3 (2023): 102491. http://dx.doi.org/10.1016/j.xpro.2023.102491.
    10.1016/j.xpro.2023.102491
  6. Carlos Saavedra; Massimo Milan; Ricardo B. Leite; David Cordero; Tomaso Patarnello; M. Leonor Cancela; Luca Bargelloni. "Transcriptional Profiling of Populations in the Clam Ruditapes decussatus Suggests Genetically Determined Differentiation in Gene Expression along Parallel Temperature Gradients and between Races of the Atlantic Ocean and West Mediterranean Sea". Fishes (2023): https://doi.org/10.3390/fishes8040203.
    10.3390/fishes8040203
  7. Vítor Borges; Joana Isidro; Nídia Sequeira Trovão; Sílvia Duarte; Helena Cortes-Martins; Hugo Martiniano; Isabel Gordo; et al. "SARS-CoV-2 introductions and early dynamics of the epidemic in Portugal". Communications Medicine 2 1 (2022): https://doi.org/10.1038/s43856-022-00072-0.
    10.1038/s43856-022-00072-0
  8. Maikel Fernández-López; Ayixon Sánchez-Reyes; Clara Barcelos; Karla Sidón-Ceseña; Ricardo B. Leite; Asunción Lago-Lestón. "Deep-Sea Sediments from the Southern Gulf of Mexico Harbor a Wide Diversity of PKS I Genes". Antibiotics 11 7 (2022): 887-887. https://doi.org/10.3390/antibiotics11070887.
    10.3390/antibiotics11070887
  9. Alenquer, Marta; Milheiro Silva, Tiago; Akpogheneta, Onome; Ferreira, Filipe; Vale-Costa, Sílvia; Medina-Lopes, Mónica; Batista, Frederico; et al. "Saliva molecular testing bypassing RNA extraction is suitable for monitoring and diagnosing SARS-CoV-2 infection in children". PLOS ONE 17 6 (2022): e0268388. http://dx.doi.org/10.1371/journal.pone.0268388.
    10.1371/journal.pone.0268388
  10. Ana M.P. Melo; Sofia Oliveira; Jorge S. Oliveira; Corinne S. Martin; Ricardo B. Leite; Leite Ricardo B.; Martin Corinne S.; et al. "Making European performance and impact assessment frameworks glocal [version 1; peer review: awaiting peer review]". (2022): https://f1000research.com/articles/11-278/v1.
    10.12688/f1000research.108804.1
  11. Simões, Alexandra Sofia; Touret, Tiago; Faria, Nuno Alexandre; Peres Ladeiro, Susana; Costa, João; Bispo, Soraia; Serrano, Mónica; et al. "Using Whole Genome Sequencing to Investigate a Mock-Outbreak of Carbapenem-Resistant Klebsiella pneumoniae in Real-Time". Acta Médica Portuguesa 35 1 (2022): 36-41. http://dx.doi.org/10.20344/amp.15174.
    Open access • Published • 10.20344/amp.15174
  12. Gonçalves, Claúdia; Kareklas, Kyriacos; Teles, Magda C; Varela, Susana.A.M.; Costa, João; Leite, Ricardo B.; Paixão, Tiago; Oliveira, Rui Filipe. "Phenotypic architecture of sociality and its associated genetic polymorphisms in zebrafish". (2022): http://hdl.handle.net/10400.12/8671.
    10.1111/gbb.12809
  13. Marta Alenquer; Michael S. Diamond; Filipe Ferreira; Diana Lousa; Mariana Valério; Mónica Medina-Lopes; Marie-Louise Bergman; et al. "Signatures in SARS-CoV-2 spike protein conferring escape to neutralizing antibodies". PLOS Pathogens (2021): https://doi.org/10.1371/journal.ppat.1009772.
    10.1371/journal.ppat.1009772
  14. Vítor Borges; Joana Isidro; Helena Cortes-Martins; Sílvia Duarte; Luís Vieira; Ricardo Leite; Isabel Gordo; et al. "Massive dissemination of a SARS-CoV-2 Spike Y839 variant in Portugal". Emerging Microbes & Infections (2020): https://doi.org/10.1080/22221751.2020.1844552.
    10.1080/22221751.2020.1844552
  15. Leite, Ricardo B. "Expression of four new ferritins from grooved carpet shell clam Ruditapes decussatus challenged with Perkinsus olseni and metals (Cd, Cu and Zn)". Aquatic Toxicology (2020): 105675-105675. http://dx.doi.org/10.1016/j.aquatox.2020.105675.
    10.1016/j.aquatox.2020.105675
  16. Wang, Xin; Wilson, Peter R.; Leite, Ricardo B.; Chen, Guiyou; Freitas, Helena; Asadi, Kamal; Smits, Edsger C. P.; Katsouras, Ilias; Rocha, Paulo R. F.. "An Energy Harvester for Low-Frequency Electrical Signals". Energy Technology (2020): 2000114. http://dx.doi.org/10.1002/ente.202000114.
    Published • 10.1002/ente.202000114
  17. Leite, Ricardo B; Churro, Catarina; Catarina Churro; Ana P. Semedo-Aguiar; Alexandra D. Silva; Jose B. Pereira-Leal; Ricardo B. Leite. "A novel cyanobacterial geosmin producer, revising GeoA distribution and dispersion patterns in Bacteria.". Scientific Reports 10 1 (2020): https://doi.org/10.1038/s41598-020-64774-y.
    Accepted • 10.1038/s41598-020-64774-y
  18. de Sousa, A.G.G.; Tomasino, M.P.; Duarte, P.; Fernández-Méndez, M.; Assmy, P.; Ribeiro, H.; Surkont, J.; et al. "Diversity and Composition of Pelagic Prokaryotic and Protist Communities in a Thin Arctic Sea-Ice Regime". Microbial Ecology (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85059694131&partnerID=MN8TOARS.
    10.1007/s00248-018-01314-2
  19. Paulo R. F. Rocha; Alexandra D. Silva; Lia Godinho; Willem Dane; Pedro Estrela; Lode K. J. Vandamme; Jose B. Pereira-Leal; Dago M. de Leeuw; Ricardo B. Leite. "Collective electrical oscillations of a diatom population induced by dark stress". Scientific Reports 8 1 (2018): https://doi.org/10.1038/s41598-018-23928-9.
    10.1038/s41598-018-23928-9
  20. Leite, Ricardo. "Microbial Diversity and Toxin Risk in Tropical Freshwater Reservoirs of Cape Verde". Toxins (2018): http://www.mdpi.com/2072-6651/10/5/186.
    10.3390/toxins10050186
  21. Carlos Saavedra; Massimo Milan; Ricardo B. Leite; David Cordero; Tomaso Patarnello; M. Leonor Cancela; Luca Bargelloni. "A Microarray Study of Carpet-Shell Clam (Ruditapes decussatus) Shows Common and Organ-Specific Growth-Related Gene Expression Differences in Gills and Digestive Gland". Frontiers in Physiology 8 (2017): https://doi.org/10.3389%2Ffphys.2017.00943.
    10.3389/fphys.2017.00943
  22. Silva, I A L; Cox, C J; Leite, R B; Cancela, M L; Conceicao, N. "Evolutionary conservation of TFIIH subunits: Implications for the use of zebrafish as a model to study TFIIH function and regulation.". Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 172-173 (2014): 9-20.
    10.1016/j.cbpb.2014.03.007
  23. Pacchiarini, T.; Cross, I.; Leite, R.B.; Gavaia, P.; Ortiz-Delgado, J.B.; Pousão-Ferreira, P.; Rebordinos, L.; Sarasquete, C.; Cabrita, E.. "Solea senegalensis vasa transcripts: Molecular characterisation, tissue distribution and developmental expression profiles". Reproduction, Fertility and Development 25 4 (2013): 646-660. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876545332&partnerID=MN8TOARS.
    10.1071/RD11240
  24. Leite, R.B.; Milan, M.; Coppe, A.; Bortoluzzi, S.; dos Anjos, A.; Reinhardt, R.; Saavedra, C.; et al. "MRNA-Seq and microarray development for the Grooved carpet shell clam, Ruditapes decussatus: A functional approach to unravel host -parasite interaction". BMC Genomics 14 1 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84886388970&partnerID=MN8TOARS.
    10.1186/1471-2164-14-741
  25. Araujo, N.C.P.; Afonso, R.; Bringela, A.; Cancela, M.L.; Cristiano, M.L.S.; Leite, R.B.. "Peroxides with antiplasmodial activity inhibit proliferation of Perkinsus olseni, the causative agent of Perkinsosis in bivalves". Parasitology International 62 6 (2013): 575-582. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885374871&partnerID=MN8TOARS.
    10.1016/j.parint.2013.06.010
  26. Rafael, M.S.; Laizé, V.; Bensimon-Brito, A.; Leite, R.B.; Schüle, R.; Cancela, M.L.. "Four-and-a-half LIM domains protein 2 (FHL2) is associated with the development of craniofacial musculature in the teleost fish Sparus aurata". Cellular and Molecular Life Sciences 69 3 (2012): 423-434. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856224817&partnerID=MN8TOARS.
    10.1007/s00018-011-0754-y
  27. Milan, M.; Coppe, A.; Reinhardt, R.; Cancela, L.M.; Leite, R.B.; Saavedra, C.; Ciofi, C.; et al. "Transcriptome sequencing and microarray development for the Manila clam, Ruditapes philippinarum: Genomic tools for environmental monitoring". BMC Genomics 12 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-79955810928&partnerID=MN8TOARS.
    10.1186/1471-2164-12-234
  28. Simão, M.F.; Leite, R.B.; Rocha, C.; Cancela, M.L.. "Changes in bioturbation of iron biogeochemistry and in molecular response of the clam ruditapes decussates upon perkinsus olseni infection". Archives of Environmental Contamination and Toxicology 59 3 (2010): 433-443. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957969737&partnerID=MN8TOARS.
    10.1007/s00244-010-9490-9
  29. Ascenso, R.M.T.; Leite, R.B.; Afonso, R.; Cancela, M.L.. "Expression pattern of Perkinsus olseni genes in response to bivalves with different susceptibility to perkinsosis". Journal of Fish Diseases 32 7 (2009): 633-636. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650803089&partnerID=MN8TOARS.
    10.1111/j.1365-2761.2009.01039.x
  30. Leite, R.B.; Brito, A.B.; Cancela, M.L.. "An Oxygen Molecular Sensor, the HIF Prolyl 4-Hydroxylase, in the Marine Protist Perkinsus olseni". Protist 159 3 (2008): 355-368. http://www.scopus.com/inward/record.url?eid=2-s2.0-45549106156&partnerID=MN8TOARS.
    10.1016/j.protis.2008.03.002
  31. Tanguy, A.; Bierne, N.; Saavedra, C.; Pina, B.; Bachère, E.; Kube, M.; Bazin, E.; et al. "Increasing genomic information in bivalves through new EST collections in four species: Development of new genetic markers for environmental studies and genome evolution". Gene 408 1-2 (2008): 27-36. http://www.scopus.com/inward/record.url?eid=2-s2.0-37549048659&partnerID=MN8TOARS.
    10.1016/j.gene.2007.10.021
  32. Elandalloussi, L.M.; Leite, R.B.; Rodrigues, P.M.; Afonso, R.; Cancela, M.L.. "Effect of the herbicide Roundup® on Perkinsus olseni in vitro proliferation and in vivo survival when infecting a permissive host, the clam Ruditapes decussatus". Bulletin of Environmental Contamination and Toxicology 80 6 (2008): 512-515. http://www.scopus.com/inward/record.url?eid=2-s2.0-46249130791&partnerID=MN8TOARS.
    10.1007/s00128-008-9412-y
  33. Elandalloussi, L.M.; Rodrigues, P.M.; Afonso, R.; Leite, R.B.; Nunes, P.A.; Cancela, M.L.. "Shikimate and folate pathways in the protozoan parasite, Perkinsus olseni". Molecular and Biochemical Parasitology 142 1 (2005): 106-109. http://www.scopus.com/inward/record.url?eid=2-s2.0-19344373699&partnerID=MN8TOARS.
    10.1016/j.molbiopara.2005.03.014
  34. Pinto, J.P.; Conceição, N.M.; Viegas, C.S.B.; Leite, R.B.; Hurst, L.D.; Kelsh, R.N.; Cancela, M.L.. "Identification of a new pebp2aA2 isoform from Zebrafish runx2 capable of inducing osteocalcin gene expression in vitro". Journal of Bone and Mineral Research 20 8 (2005): 1440-1453. http://www.scopus.com/inward/record.url?eid=2-s2.0-22744449747&partnerID=MN8TOARS.
    10.1359/JBMR.050318
  35. Elandalloussi, L.M.; Leite, R.B.; Rodrigues, P.M.; Afonso, R.; Nunes, P.A.; Cancela, M.L.. "Effect of antiprotozoal drugs on the proliferation of the bivalve parasite Perkinsus olseni". Aquaculture 243 1-4 (2005): 9-17. http://www.scopus.com/inward/record.url?eid=2-s2.0-10644265408&partnerID=MN8TOARS.
    10.1016/j.aquaculture.2004.09.038
  36. Leite, R.B.; Afonso, R.; Cancela, M.L.. "Perkinsus sp. infestation in carpet-shell clams, Ruditapes decussatus (L), along the Portuguese coast. Results from a 2-year survey". Aquaculture 240 1-4 (2004): 39-53. http://www.scopus.com/inward/record.url?eid=2-s2.0-4744368358&partnerID=MN8TOARS.
    10.1016/j.aquaculture.2004.05.014
  37. Elandalloussi, L.M.; Leite, R.M.; Afonso, R.; Nunes, P.A.; Robledo, J.A.F.; Vasta, G.R.; Cancela, M.L.. "Development of a PCR-ELISA assay for diagnosis of Perkinsus marinus and Perkinsus atlanticus infections in bivalve molluscs". Molecular and Cellular Probes 18 2 (2004): 89-96. http://www.scopus.com/inward/record.url?eid=2-s2.0-1642502971&partnerID=MN8TOARS.
    10.1016/j.mcp.2003.09.008

Intellectual property

Patent
  1. Leite, Ricardo B; Maria de Lurdes Cristiano; Lilia Cabral; Jose B. Pereira-Leal. 2020. "New endoperoxide compounds, process for obtaining them and uses thereof for control of perkinsiosis in bivalves". United States.
    Granted/Issued
  2. Leite, Ricardo B. 2015. "Expression constructs comprising a Terebella lapidaria nucleic acid encoding a cellulase, host cells, and methods of making the cellulase". United States.
    Granted/Issued
  3. Leite, Ricardo B. 2015. "Polypeptides having cellulase activity and polynucleotides encoding same".
    Granted/Issued
  4. Schnorr, KM; Leonor Cancela; Leite, Ricardo B; Anderson L. 2013. "Polypeptides having cellulose activity and polynucleotides encoding same".
    Granted/Issued
  5. Leite, Ricardo B. 2012. "Dfpase enzymes from aplysia californica". United States.
    Granted/Issued
  6. Leite, Ricardo B. 2012. "Dfpase enzymes from octopus vulgaris". United States.
  7. Leonor Cancela; Laizé, V; Leite, Ricardo B; Danielsen S; Skov LK. 2010. "New isolated polypeptide having organophosphorous hydrolase activity selected from polypeptide containing amino acid sequence, polypeptide encoded by polynucleotide, variant containing deletion of amino acids, used in nucleic acid construct". United States.
    Granted/Issued
  8. Leonor Cancela; Laizé, V; Leite, Ricardo B; Danielsen, Steffen ; Skov LK. 2010. "New isolated polypeptide with organophosphorus hydrolase activity selected from e.g. polypeptide with amino acid sequence having specific identity to mature polypeptide and polypeptide encoded by polynucleotide, used in such as composition". Denmark.
    Granted/Issued

Other

Other output
  1. Phenotypic architecture of sociality and its associated genetic polymorphisms in zebrafish. 2021. Claúdia Gonçalves; Kyriacos Kareklas; Magda C. Teles; Susana A. M. Varela; João Costa; Ricardo B. Leite; Tiago Paixão; Rui F. Oliveira. https://doi.org/10.1101/2021.07.29.454277.
    10.1101/2021.07.29.454277
  2. Microbial diversity and toxin risk in tropical freshwater reservoirs of Cape Verde. 2018. Ana Paula Semedo-Aguiar; Jose Bartholo Pereira-Leal; Ricardo Bastos Leite. https://doi.org/10.1101/266957.
    10.1101/266957
Activities

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2014 - 2025/11/07 Metabolic diversity in aquatic phytoplankton, The richness of secondary metabolite production of Cyanobacteria
Co-supervisor of Ana Paula de Sousa Monteiro Semedo d Aguiar
 Molecular Biosciences - Biology (PhD)
Universidade Nova de Lisboa, Portugal
2020 - 2021 Adaptation Of Genoqual Pipeline To New Upstream Applications And To Run Independently From Galaxy
Co-supervisor of joão pedro fernandes lourenço da filomena
 Engenharia Biológica e Química (Master)
Instituto Politécnico de Setúbal Escola Superior de Tecnologia do Barreiro, Portugal
2009 - 2010 Identification and characterization of two Ferritin Isoforms from the clam R. decussatus and evaluation of some of its biological properties
Co-supervisor
 Mestrado em Molecular e Biologia Microbiana (Master)
Universidade do Algarve, Portugal
2004 - 2006 Estudos sobre aproveitamento biotecnológico da quitina produzida por organismos marinhos
Co-supervisor
 Mestrado em Biotecnologia (Master)
Universidade do Algarve, Portugal