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Identification

Personal identification

Full name
ANA MARTA MARTINS VALENTE PINTO

Citation names

  • Pinto, MV
  • Marta Valente Pinto
  • Valente Pinto, M

Author identifiers

Ciência ID
EE1D-5814-EF64
ORCID iD
0000-0002-9716-7848
Education
Degree Classification
2016/10/01 - 2021/06/30
Concluded
DPhil in Paediatrics (Doctor of Philosophy)
Major in Vaccinology
University of Oxford, United Kingdom
2020/11/01 - 2021/06/01
Concluded
Professional Diploma in Travel Health (Postgraduate Certificate)
Liverpool School of Tropical Medicine, United Kingdom
Distinction
2014/09/01 - 2015/12/01
Concluded
Harvard Medical School - Fundação para a Ciência e Tecnologia (FCT) - Portugal Program in Translational Research and Information (Especialização pós-licenciatura)
Fundação para a Ciência e a Tecnologia, Portugal
2009/01/01 - 2015/04/15
Concluded
Especialista em Pediatria (Título de especialista)
Centro Hospitalar Lisboa Norte EPE, Portugal
19.4
2009/09/01 - 2010/06/30
Concluded
Doenças Infecciosas Emergentes (Pós-Graduação)
Universidade de Lisboa: Faculdade de Medicina, Portugal
17
2001/09/01 - 2007/06/15
Concluded
Licenciatura em Medicina (Licenciatura)
Universidade de Lisboa: Faculdade de Medicina, Portugal
17
Affiliation

Teaching in Higher Education

Category
Host institution
Employer
2022/02/01 - Current Assistant Professor (University Teacher) Egas Moniz Cooperativa de Ensino Superior CRL, Portugal
2007/09/01 - 2013/06/30 Assistant (University Teacher) Universidade de Lisboa: Faculdade de Medicina, Portugal

Other Careers

Category
Host institution
Employer
2020/05/20 - Current Assistente (Médica) Centro Hospitalar de Lisboa Central EPE, Portugal
2009/01/01 - 2015/05/01 Interno (Médica) Centro Hospitalar Lisboa Norte EPE, Portugal
Projects

Grant

Designation Funders
2026/01/06 - 2028/03/31 Gripe em idade Pediátrica – Estudo multicêntrico da avaliação da carga da doença, efetividade vacinal e impacto na qualidade de vida das crianças e das famílias em Portugal – Projeto GRICEIQ
Co-Principal Investigator (Co-PI)
Sociedade Portuguesa de Pediatria
Under evaluation

Other

Designation Funders
2024/10/27 - 2025/10/01 Respiratory Syncytial Virus Mutational Profile during a Pharmacological Prophylactic Intervention
NA
Principal investigator
Egas Moniz Cooperativa de Ensino Superior CRL, Portugal
Sociedade Portuguesa de Pediatria
Ongoing
Outputs

Publications

Journal article
  1. Aapo Knuutila; Niina Ahvenainen; Alex-Mikael Barkoff; Jussi Mertsola; Pieter van Gageldonk; Annemarie Buisman; Marta Valente Pinto; Dominic Kelly; Qiushui He. "Prior immunological memory to pertussis toxin affects the avidity development of anti-PT IgG antibodies after acellular pertussis booster vaccination". Emerging Microbes & Infections (2025): http://dx.doi.org/10.1080/22221751.2025.2547720.
    10.1080/22221751.2025.2547720
  2. Anja Saso; Ebrima Kanteh; David Jeffries; Michael Okoye; Nuredin Mohammed; Michelle Kumado; Sophie Roetynck; et al. "The effect of pertussis vaccination in pregnancy on the immunogenicity of acellular or whole-cell pertussis vaccination in Gambian infants (GaPS): a single-centre, randomised, controlled, double-blind, phase 4 trial". The Lancet Infectious Diseases (2025): http://dx.doi.org/10.1016/s1473-3099(25)00072-6.
    10.1016/s1473-3099(25)00072-6
  3. Catarina Andrade; Miguel de Almeida Cordeiro; Rute Baeta Baptista; Beatriz Sousa Nunes; Ana Margarida Garcia; Tiago Milheiro Silva; Marta Valente Pinto. "Post-varicella vaccination uveitis in a child with nephrotic syndrome receiving immunosuppressive treatment: a case report". Frontiers in Pediatrics (2025): http://dx.doi.org/10.3389/fped.2025.1567164.
    10.3389/fped.2025.1567164
  4. Catarina Andrade; Ana Isabel Cordeiro; Marta Valente Pinto; Conceição Neves; Catarina Martins; Jean-Pierre Villartay; João Farela Neves. "Case Report: Hypomorphic Ligase 4 deficiency – a paradigm of immunodysregulation". Frontiers in Immunology (2025): http://dx.doi.org/10.3389/fimmu.2025.1545630.
    10.3389/fimmu.2025.1545630
  5. Marta Valente Pinto; Alex-Mikael Barkoff; Sagida Bibi; Aapo Knuutila; Johanna Teräsjärvi; Elizabeth Clutterbuck; Sophie Gimenez-Fourage; et al. "A novel whole blood assay to quantify the release of T cell associated cytokines in response to Bordetella pertussis antigens". Journal of Immunological Methods (2024): http://dx.doi.org/10.1016/j.jim.2024.113758.
    10.1016/j.jim.2024.113758
  6. Joshua Gillard; Madeleine Suffiotti; Peter Brazda; Prashanna B. Venkatasubramanian; Pauline Versteegen; Marien de Jonge; Dominic Kelly; et al. "Antiviral responses induced by Tdap-IPV vaccination are associated with persistent humoral immunity to Bordetella pertussis". Nature Communications (2024): http://dx.doi.org/10.1038/s41467-024-46560-w.
    10.1038/s41467-024-46560-w
  7. Kushalinii Hillson; Jonathan Kantor; Marta Valente Pinto; Andrew J. Pollard; Dominic Kelly; Samantha Vanderslott; the AWARE clinical trial team. "Motivations for paediatric vaccine trial participation". Trials 24 1 (2023): http://dx.doi.org/10.1186/s13063-023-07597-2.
    10.1186/s13063-023-07597-2
  8. Inês Hormigo; Marta Valente Pinto; Ana Isabel Cordeiro; Cristina Henriques; Catarina Martins; João Parente Freixo; Marta Conde; Catarina Gouveia; João Farela Neves. "Hemophagocytic lymphohistiocytosis in an adolescent with NLRP12 related autoinflammatory disorder—A case report". Pediatric Allergy and Immunology 34 9 (2023): http://dx.doi.org/10.1111/pai.14020.
    10.1111/pai.14020
  9. Diana Simão Raimundo; Ana Isabel Cordeiro; João Parente Freixo; Marta Valente Pinto; Conceição Neves; João Farela Neves. "Case Report: Patient with deficiency of ADA2 presenting leukocytoclastic vasculitis and pericarditis during infliximab treatment". Frontiers in Pediatrics 11 (2023): http://dx.doi.org/10.3389/fped.2023.1200401.
    10.3389/fped.2023.1200401
  10. Pinto, Marta Valente; Neves, João Farela. "Precision medicine: The use of tailored therapy in primary immunodeficiencies". Frontiers in Immunology 13 (2022): http://dx.doi.org/10.3389/fimmu.2022.1029560.
    Open access • 10.3389/fimmu.2022.1029560
  11. Marta Valente Pinto; Pedro Simão Coelho; Catarina Gouveia; Conceição Neves; Ana Isabel Cordeiro; João Farela Neves. "Recurrent pyogenic infections caused by a novel Gln1420* mutation in the C3 gene". Frontiers in Pediatrics 10 (2022): http://dx.doi.org/10.3389/fped.2022.1017195.
    10.3389/fped.2022.1017195
  12. Versteegen, Pauline; Barkoff, Alex-Mikael; Valente Pinto, Marta; van de Kasteele, Jan; Knuutila, Aapo; Bibi, Sagida; de Rond, Lia; et al. "Memory B Cell Activation Induced by Pertussis Booster Vaccination in Four Age Groups of Three Countries". Frontiers in Immunology 13 (2022): http://dx.doi.org/10.3389/fimmu.2022.864674.
  13. Marta Valente Pinto; Pauline Versteegen; Alex-Mikael Barkoff; Jan van de Kasteele; Aapo Knuutila; Sagida Bibi; Lia de Rond; et al. "Memory B Cell Activation Induced by Pertussis Booster Vaccination in Four Age Groups of Three Countries". Frontiers in Immunology 13 (2022): http://dx.doi.org/10.3389/fimmu.2022.864674.
    10.3389/fimmu.2022.864674
  14. Coelho, Pedro Simão; Gouveia, Catarina; Pinto, Marta Valente; Neves, Conceição; Cordeiro, Ana Isabel; Neves, João Farela. "Recurrent pyogenic infections caused by a novel Gln1420* mutation in the C3 gene". (2022): http://hdl.handle.net/10362/145222.
    https://doi.org/10.3389/fped.2022.1017195
  15. Davis, Kimberly; Valente Pinto, Marta; Andrews, Nick J; Goldblatt, David; Borrow, Ray; Findlow, Helen; Southern, Jo; et al. "Immunogenicity of the UK group B meningococcal vaccine (4CMenB) schedule against groups B and C meningococcal strains (Sched3): outcomes of a multicentre, open-label, randomised controlled trial". The Lancet Infectious Diseases 21 5 (2021): 688-696. http://dx.doi.org/10.1016/s1473-3099(20)30600-9.
    10.1016/s1473-3099(20)30600-9
  16. Versteegen, Pauline; Valente Pinto, Marta; Barkoff, Alex M.; van Gageldonk, Pieter G.M.; van de Kassteele, Jan; van Houten, Marlies A.; Sanders, Elisabeth A.M.; et al. "Responses to an acellular pertussis booster vaccination in children, adolescents, and young and older adults: A collaborative study in Finland, the Netherlands, and the United Kingdom". EBioMedicine 65 (2021): 103247. http://dx.doi.org/10.1016/j.ebiom.2021.103247.
    10.1016/j.ebiom.2021.103247
  17. Valente Pinto, Marta; Davis, Kimberly; Andrews, Nick; Goldblatt, David; Borrow, Ray; Southern, Jo; Nordgren, Ida Karin; et al. "Understanding the reactogenicity of 4CMenB vaccine: Comparison of a novel and conventional method of assessing post-immunisation fever and correlation with pre-release in vitro pyrogen testing". Vaccine 38 49 (2020): 7834-7841. http://dx.doi.org/10.1016/j.vaccine.2020.10.023.
    10.1016/j.vaccine.2020.10.023
  18. O’Connor, Daniel; Pinto, Marta Valente; Sheerin, Dylan; Tomic, Adriana; Drury, Ruth E; Channon-Wells, Samuel; Galal, Ushma; et al. "Gene expression profiling reveals insights into infant immunological and febrile responses to group B meningococcal vaccine". Molecular Systems Biology 16 11 (2020): http://dx.doi.org/10.15252/msb.20209888.
    10.15252/msb.20209888
  19. Valente Pinto, Marta; O’Connor, Daniel; Galal, Ushma; Clutterbuck, Elizabeth A; Robinson, Hannah; Plested, Emma; Bibi, Sagida; et al. "Immunogenicity and Reactogenicity of a Reduced Schedule of a 4-component Capsular Group B Meningococcal Vaccine: A Randomized Controlled Trial in Infants". Open Forum Infectious Diseases 7 5 (2020): http://dx.doi.org/10.1093/ofid/ofaa143.
    10.1093/ofid/ofaa143
  20. Valente Pinto, Marta. "The COVID-19 Pandemic: Can it Play a Role in Vaccine Acceptance or Contribute to Vaccine Hesitancy?". (2020): https://doi.org/10.25754/pjp.2020.20445.
    https://doi.org/10.25754/pjp.2020.20445
  21. Goldblatt, David; Southern, Jo; Andrews, Nick J; Burbidge, Polly; Partington, Jo; Roalfe, Lucy; Valente Pinto, Marta; et al. "Pneumococcal conjugate vaccine 13 delivered as one primary and one booster dose (1¿+¿1) compared with two primary doses and a booster (2¿+¿1) in UK infants: a multicentre, parallel group randomised controlled trial". The Lancet Infectious Diseases 18 2 (2018): 171-179. http://dx.doi.org/10.1016/s1473-3099(17)30654-0.
    10.1016/s1473-3099(17)30654-0
  22. Pinto, Marta V.; Merkel, Tod J.. "Pertussis disease and transmission and host responses: insights from the baboon model of pertussis". Journal of Infection 74 (2017): S114-S119. http://dx.doi.org/10.1016/s0163-4453(17)30201-3.
    10.1016/s0163-4453(17)30201-3
  23. Rodrigues, Charlene M.C.; Pinto, Marta V.; Sadarangani, Manish; Plotkin, Stanley A.. "Whither vaccines?". Journal of Infection 74 (2017): S2-S9. http://dx.doi.org/10.1016/s0163-4453(17)30184-6.
    10.1016/s0163-4453(17)30184-6
  24. Pinto, Marta Valente; Bihari, Smiti; Snape, Matthew D.. "Immunisation of the immunocompromised child". Journal of Infection 72 (2016): S13-S22. http://dx.doi.org/10.1016/j.jinf.2016.04.017.
    10.1016/j.jinf.2016.04.017
  25. Leivers, C.; Martin, G.; Gasparetto, M.; Shelley, H.; Valente, M.. "Coeliac disease". Paediatrics and Child Health 24 11 (2014): 481-484. http://dx.doi.org/10.1016/j.paed.2014.05.004.
    10.1016/j.paed.2014.05.004
  26. Valente Pinto, M.; Esteves, I.; Bryceson, Y.; Ferrao, A.. "Hemophagocytic syndrome with atypical presentation in an adolescent". Case Reports 2013 sep11 1 (2013): bcr2013200929-bcr2013200929. http://dx.doi.org/10.1136/bcr-2013-200929.
    10.1136/bcr-2013-200929
Activities

Consulting

Activity description Institution / Organization
2022/07/15 - Current Presidente da Comissão Técnica da Vacinação da Direção-Geral de Saúde
Distinctions

Award

2006 Bolsa de Mérito para as 3 melhores classificações da Faculdade de Medicina da Universidade de Lisboa