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Ana Raquel-Cunha has a degree in Applied Biology (2014/2017), a post-graduation in Applied Biochemistry(2017/2018) and a master's degree in Health Sciences by University of Minho (2018/2019). She is, since September 2019, a PhD student in the doctoral program of Health Sciences in University of Minho, developing her dissertation in understanding the role of RKIP protein as a novel predictor of EGFR targeted therapies in lung cancer. She has 2 published articles, 2 book chapters, 2 oral presentations and 20 conference posters. Additionally, during her path she mentored 5 students. In her curriculum Ciência Vitae the most frequent terms in the context of scientific and technological outputs are: RKIP; lung cancer; biomarker; oncobiology; cancer; molecular targeted therapies.
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Identification

Personal identification

Full name
Ana Raquel Ferreira Cunha

Citation names

  • Raquel-Cunha, Ana

Author identifiers

Ciência ID
EE1B-ABAA-6772

Email addresses

  • id8805@alunos.uminho.pt (Professional)

Telephones

Telephone
  • 253604837 (Professional)

Addresses

  • Campus de Gualtar, University of Minho, 4710-057 , Gualtar, Braga, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Health Sciences
  • Medical and Health Sciences - Clinical Medicine - Oncology
  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Molecular Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2019/09/01 - 2023/09
Ongoing
 Ciências da Saúde (Doutoramento)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2021/03/02 - 2021/03/12
Concluded
 Cell Functional and Phenotypical Analysis: the usefulness of Flow Cytometry and related tools (Curso de doutoramento (conclusão de unidades curriculares))
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/09 - 2019/07
Concluded
 Ciências da Saúde (Mestrado)
Major in Master
Universidade do Minho Escola de Medicina, Portugal
"Exploiting RKIP protein as a novel predictor of EGFR targeted therapies response in lung cancer" (THESIS/DISSERTATION)
 18
2019/02/25 - 2019/03/22
Concluded
 Establishment of lung cancer xenograft models (Outros)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/01/28 - 2019/02/08
Concluded
 Laboratory Animal Science (Curso de mestrado (conclusão do curso de especialização))
Universidade do Minho Escola de Medicina, Portugal
 16
2018/07/02 - 2018/07/13
Concluded
 Protein Degradation and Trafficking in Health and Disease (Curso de mestrado (conclusão do curso de especialização))
Universidade do Minho Escola de Ciências, Portugal
 19
2017/09 - 2018/07
Concluded
 Bioquímica Aplicada (Pós-Graduação)
Major in Biomedicina
Universidade do Minho Escola de Ciências, Portugal
 17
2018/04/23 - 2018/04/27
Concluded
 Nanoparticles and the immune system: risks and therapeutic opportunities (Curso de mestrado (conclusão do curso de especialização))
Universidade do Minho Escola de Ciências, Portugal
 16
2014/09 - 2016/07
Concluded
 Biologia Aplicada (Licenciatura)
Universidade do Minho Escola de Ciências, Portugal
"A proteína RKIP como um novo preditor de resposta a terapias moleculares dirigidas em cancro do pulmão" (THESIS/DISSERTATION)
 16
Affiliation

Others

Category
Host institution 		Employer
2019/09 - Current PhD Student Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2018/09 - 2019/07 Master's Student Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Universidade do Minho Escola de Medicina, Portugal
2017/09 - 2018/05 Voluntary Internship Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2012/06/04 - 2012/06/06 Internship Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal
Projects

Grant

Designation Funders
2019/09/01 - Current RKIP protein as a novel predictor of EGFR targeted therapy response in lung cancer
SFRH/BD/148199/2019
PhD Student Fellow
Ongoing

Other

Designation Funders
2017/05 - 2018 Exploring RKIP protein as a novel predictor of oncogene targeted therapies in cancer
SFRH/BPD/108351/2015
Other
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Cardoso-Carneiro, Diana; Raquel-Cunha, Ana; Pinheiro, Joana; Gabriela-Freitas, Maria; Fontão, Patrícia; Reis, Rui M.; Martinho, Olga. "Implications of RKIP protein in cancer prognosis and therapy response: A literature update". In Prognostic and Therapeutic Applications of RKIP in Cancer, edited by Benjamin Bonavida; Stavroula Baritaki, 389-414. Elsevier, 2020.
    10.1016/b978-0-12-819612-0.00020-1
  2. Olívia Pontes; Ana Raquel-Cunha; Sofia Oliveira-Pinto; Fátima Baltazar; Olga Martinho; Marta Costa. "Chromene-based compounds as promising antiangiogenic therapeutic agents". In Anti-Angiogenesis Drug Discovery and Development, edited by Mariam Mehdi. Amsterdam, Netherlands: Bentham Science publishes eBooks, 2019.
    Accepted
Conference poster
  1. Fontão, Patrícia; Mendes, Adriana; Raquel-Cunha, Ana; Martinho, Olga; Reis, Rui M.. "Embryonic T-box transcription factor Brachyury in androgen-dependent prostate cancer models". Paper presented in EACR 2022 Congress - Innovative Cancer Science: Translating Biology to Medicine, 2022.
  2. Raquel-Cunha, Ana; Pinheiro, Joana; Cardoso-Carneiro, Diana; Fontão, Patrícia; Mendes, Adriana; Gabriela-Freitas, Maria; Reis, Rui M.; Martinho, Olga. "The implication of RKIP loss in primary resistance to EGFR inhibitors in NSCLC: a novel predictive biomarker?". Paper presented in EACR 2022 Congress - Innovative Cancer Science: Translating Biology to Medicine, 2022.
  3. Raquel-Cunha, Ana; Pinheiro, Joana; Cardoso-Carneiro, Diana; Fontão, Patrícia; Gabriela-Freitas, Maria; Reis, Rui Manuel; Martinho, Olga. "Untangling the role of RKIP in NSCLC aggressiveness: an in vitro /in vivo and in silico analysis". Paper presented in II ASPIC-ASEICA International Meeting – Current Trends in Precision Medicine in Cancer, 2021.
  4. Pinheiro, Joana; Fontão, Patrícia; Gabriela-Freitas, Maria; Cardoso-Carneiro, Diana; Raquel-Cunha, Ana; Granja, Sara; Martinho, Olga. "Role of RKIP protein in the modulation of lung cancer cell metabolism". Paper presented in II ASPIC-ASEICA International Meeting – Current Trends in Precision Medicine in Cancer, 2021.
  5. Raquel-Cunha, Ana; Pinheiro, Joana; Cardoso-Carneiro, Diana; Fontão, Patrícia; Gabriela-Freitas, Maria; Reis, Rui Manuel; Martinho, Olga. "A proteína RKIP como um novo preditor de resposta a terapias anti-EGFR em cancro do pulmão". Paper presented in 3º Encontro Nacional de Jovens Investigadoresem Oncologia, 2021.
  6. Fontão, Patrícia; Raquel-Cunha, Ana; Cardoso-Carneiro, Diana; Pinheiro, Joana; Gabriela-Freitas, Maria; Mendes, Adriana; Reis, Rui Manuel; Martinho, Olga. "Fator de transcrição embrionário T-boxBrachyury como biomarcador de resposta e alvo terapêutico em cancro do pulmão". Paper presented in 3º Encontro Nacional de Jovens Investigadoresem Oncologia, 2021.
  7. Cardoso-Carneiro, Diana; Raquel-Cunha, Ana; Fontão, Patrícia; Pinheiro, Joana; Gabriela-Freitas, Maria; Nogueira, Rosete; Reis, Rui Manuel; Martinho, Olga. "Compreender a regulação e sinalização da RKIP no cancro do colo do útero: RKIP/HER loop". Paper presented in 3º Encontro Nacionalde Jovens Investigadoresem Oncologia, 2021.
  8. Fontão, Patrícia; Raquel-Cunha, Ana; Cardoso-Carneiro, Diana; Pinheiro, Joana; Gabriela-Freitas, Maria; Mendes, Adriana; Reis, Rui Manuel; Martinho, Olga. "Exploring the predictive andtherapeutic value of the embryonic T-box transcription factor Brachyury in lung cancer". Paper presented in II ASPIC-ASEICA International Meeting -Current Trends in Precision Medicine in Cancer, 2021.
  9. Raquel-Cunha, Ana; Pinheiro, Joana; Diana Cardoso-Carneiro; Gabriela-Freitas, Maria; Fontão, Patrícia; Manuel Reis, RUI; Martinho, Olga. "RKIP protein as a novel predictor of EGFR targeted therapies in lung cancer". Paper presented in EACR 2021 Congress, Innovative Cancer Science: Better Outcomes through Research, 2021.
  10. Fontão, Patrícia; Raquel-Cunha, Ana; Cardoso-Carneiro, Diana; Pinheiro, Joana; Gabriela-Freitas, Maria; Mendes, Adriana; Martinho, Olga; Reis, Rui Manuel. "Embryonic T-box transcription factor Brachyury as a predictive biomarker andtherapeutic target in lung cancer". Paper presented in 27th Porto CancerMeeting – Stemness & Metastasis: Advances in Research and Clinical Translation, 2021.
  11. Joana Pinheiro; Maria Gabriela-Freitas; Diana Cardoso-Carneiro; Raquel-Cunha, Ana; Sara Granja; Olga Martinho. "Role of RKIP protein in the modulation of cancer cells metabolism in solid tumors". Paper presented in 6th meeting of ISCaM, 2019.
  12. Diana Cardoso-Carneiro; Patrícia Vaz-Cunha; Rosete Nogueira; Raquel-Cunha, Ana; Ana Carolina Peters; André L. Carvalho; Rui M. Reis; Olga Martinho. "RKIP protein as a potential prognostic, aggressiveness and therapy response biomarker in HNSCC". Paper presented in VII International Symposium on Translational Oncology, 2019.
  13. Ana Raquel-Cunha; Joana Pinheiro; Diana Cardoso-Carneiro; Gabriela Freitas; Rui M. Reis ; Olga Martinho. "RKIP protein as a novel predictor of EGFR targeted therapies in lung cancer". Paper presented in 3rd Annual Meeting CINBIO, 2019.
  14. Raquel-Cunha, Ana; Joana Pinheiro; Diana Cardoso-Carneiro; Gabriela Freitas; Rui M. Reis ; Olga Martinho. "RKIP protein as a novel predictor of EGFR targeted therapies in lung cancer". Paper presented in ICVS Open day 2019, 2019.
  15. Diana Cardoso-Carneiro; Gabriela Freitas; Raquel-Cunha, Ana; Joana Pinheiro; Rui M. Reis ; Olga Martinho. "RKIP protein induces HER receptors activation and positively modulate its pharmacological targeting in cervical cancer". Paper presented in ICVS Open Day 2019, 2019.
  16. Ana Raquel-Cunha; Nuno Alves; Diana Cardoso-Carneiro; Rui M. Reis ; Olga Martinho. "RKIP protein as a novel predictor of EGFR targeted therapies in lung cancer.". Paper presented in SINAL 2018- 9th Meeting on Signal Transduction, 2018.
  17. Diana Cardoso-Carneiro; Ana Raquel-Cunha; Rosete Nogueira; Rui M. Reis ; Olga Martinho. "RKIP protein induces HER receptors activation and positively modulate its pharmacological targeting in cervical cancer.". Paper presented in SINAL 2018- 9th Meeting on Signal Transduction, 2018.
  18. Diana Cardoso-Carneiro; Ana Raquel-Cunha; Rosete Nogueira; Rui M. Reis ; Olga Martinho. "RKIP protein induces HER receptors activation and positively modulate its pharmacological targeting in cervical cancer". Paper presented in 3rd ASPIC International Congress, 2018.
  19. Diana Cardoso-Carneiro; Ana Raquel-Cunha; Rosete Nogueira; Rui M. Reis ; Olga Martinho. "RKIP protein induces HER receptors activation and positively modulate its pharmacological targeting in cervical cancer.". Paper presented in Porto Cancer Meeting 2018, 2018.
  20. Ana Raquel-Cunha; Nuno Alves; Diana Cardoso-Carneiro; Rui M. Reis ; Olga Martinho. "RKIP protein as a novel predictor of EGFR targeted therapies in lung cancer.". Paper presented in ICVS Open Day 2018, 2018.
  21. Diana Cardoso-Carneiro; Ana Raquel-Cunha; Rosete Nogueira; Rui M. Reis ; Olga Martinho. "RKIP protein induces HER receptors activation and positively modulate its pharmacological targeting in cervical cancer". Paper presented in ICVS Open Day 2018, 2018.
  22. Patrícia Vaz-Cunha; Diana Cardoso-Carneiro; Ana Raquel-Cunha; André Lopes Carvalho; Rui M. Reis ; Olga Martinho. "The biological role of RKIP in head and neck cancer: an in vivo and in vitro study". Paper presented in ICVS Open Day 2018, 2018.
Journal article
  1. Gabriela-Freitas; Pinheiro; Raquel-Cunha; Cardoso-Carneiro; Martinho. "RKIP as an Inflammatory and Immune System Modulator: Implications in Cancer". Biomolecules 9 12 (2019): 769. http://dx.doi.org/10.3390/biom9120769.
    10.3390/biom9120769
  2. Raquel-Cunha, Ana; Cardoso-Carneiro, Diana; Reis, Rui M.; Martinho, Olga. "Current Status of Raf Kinase Inhibitor Protein (RKIP) in Lung Cancer: Behind RTK Signaling". Cells 8 5 (2019): 442. http://dx.doi.org/10.3390/cells8050442.
    10.3390/cells8050442
Thesis / Dissertation
  1. Raquel-Cunha, Ana. "Exploiting RKIP protein as a novel predictor of EGFR targeted therapies response in lung cancer". Master, Universidade do Minho Escola de Medicina, 2019.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2019/04/12 RKIP Protein As A Novel Predictor Of EGFR Targeted Therapy In Lung Cancer ICVS Open day 2019
Instituto de Investigação em Ciências da Vida e Saúde (Braga, Portugal)
2018/04/25 RKIP protein induces HER receptors activation and positively modulate its pharmacological targeting in cervical cancer Porto Cancer Meeting
(Porto, Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2017/02 - Current Organizer in XVIII Jornadas de Biologia Aplicada (2017/02)
Meeting (Member of the Organising Committee)
 Universidade do Minho Escola de Ciências, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2019/03/13 - Current Research on cell signaling and therapy applied to oncobiology
Workshop
 I Jornadas da Ciência
Universidade do Minho Escola de Ciências, Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
2019/03 - Current Participation in activity called "Simpósio do Futuro", giving my testimony as former student of Applied Biology, and my journy until now as a master student and young investigator.
Meeting
 I Jornadas da Ciência
Universidade do Minho Escola de Ciências, Portugal
2018/04 - 2018/04 Oral participant in a “Speed Meeting” to give testimony to describe experience as young investigator.
Meeting
 XIX Jornadas de Biologia Aplicada
Universidade do Minho Escola de Ciências, Portugal

Mentoring / Tutoring

Topic Student name
2021/12/01 - 2022/02/14 Exploring RKIP chemical induction as a novel adjuvant of EGFR targeted therapy response in lung cancer Ariana Silva
2019/11/04 - 2019/12/13 Study of the influence of HPV infection in RKIP expression in cervical cancer Beatriz Barcellos
2019/04/24 - 2019/06/01 Efeito biológico da expressão da RKIP em linhas celulares de cancro de pulmão Rita Caridade Silva
2018/11 - 2018/12 Raf kinase inhibitor protein (RKIP) as a modulator of oncogene targeted therapies response in Colon Cancer Joana Pinheiro
2018/07/01 - 2018/07/31 Biological effect of RKIP expression in lung cancer cell lines Bruna Araújo