???global.info.a_carregar???
Solange Trindade Castanheira holds a BSc in Medicinal Chemistry from the Faculty of Sciences and Technology, University of Coimbra (2022). She carried out research at the Institute for Clinical and Biomedical Research (iCBR) as part of her undergraduate internship, investigating the role of Piezo-1 mechanoreceptor activation in microglial neuroinflammation and contributing to the understanding of mechanotransduction in neuroimmune responses. She completed an MSc in Pharmacy, with a specialization in Pharmacotherapy and Pharmacoepidemiology, at the Polytechnic Institute of Porto – School of Health (2024). Her dissertation, “Preliminary study for the development of innovative pharmaceutical forms for the pediatric population,” addressed unmet clinical needs in pediatric drug delivery, focusing on formulation development, stability, palatability and adherence-related challenges. This work included the development of prednisolone-based gummy formulations and supported a first-author manuscript currently under review at the International Journal of Pharmaceutics (submitted 2026). Her scientific activity includes publications, conference presentations and participation in funded research projects. She co-authored an umbrella review on SGLT2 inhibitors in chronic kidney disease, published as an abstract in RevSALUS (2024; DOI: 10.51126/revsalus.v5iSupii.665) and presented as an oral communication at the LusoSaúde Scientific Days. She also presented a poster on innovative pediatric formulations at Congresso Nacional dos Farmacêuticos with the abstract published in the Revista Portuguesa de Farmacoterapia (2024; DOI: 10.25756/rpf.v15i3-4.315). She contributed to the FRUIGU project (UIDB/05704/2020), focused on functional food development through fruit residue valorization, and presented the work entitled “Desenvolvimento de gomas saudáveis e sustentáveis: uma estratégia de valorização dos resíduos de maçã de Alcobaça” at the 7º Simpósio de Produção e Transformação de Alimentos Sustentáveis (ISBN: 978-972-579-080-9). She also engaged in science communication and outreach, participating in initiatives such as ciTechCare Ciência Viva – Science and Technology Week (2025), where she delivered educational sessions in schools related to the FRUIGU project. Since May 2025, she has been a research fellow at ciTechCare (Center for Innovative Care and Health Technology, Polytechnic of Leiria), within the MAP02 – Medication Adherence Platform funded project (FEDER;01487800). MAP02 is a co-promotion initiative with companies in the health technology sector, fostering a translational ecosystem for knowledge transfer to society. This experience has strengthened her interest in academia–industry integration as a key driver for the development, validation, and implementation of innovative health solutions. She recognizes this interface as essential to bridge scientific knowledge with real-world application and to accelerate the translation of research into clinical and societal impact. Her work focuses on developing digital health solutions and a medical device to improve medication adherence and supporting patient-centered care, including data analysis and implementation of technology-based strategies in real-world settings. The experience she acquired in scientific literature review, experimental design and data interpretation, together with multidisciplinary collaboration, has strengthened her ability to integrate knowledge across pharmaceutical sciences, nutrition and biomedical research. Her research profile lies at the interface of these fields and digital health, focusing on real-world health outcomes and the determinants of treatment effectiveness. Her current research focuses on the interplay between biological and behavioral factors, supporting personalized strategies for disease prevention and management.
Identification

Personal identification

Full name
Solange Trindade Castanheira
Date of birth
2001/10/11
Gender
Female

Citation names

  • Castanheira, Solange

Author identifiers

Ciência ID
ED19-A63A-D33F
ORCID iD
0009-0007-6471-3009

Email addresses

  • solange.castanheira@ipleiria.pt (Professional)

Telephones

Mobile phone
  • (+351) 913023387 (Personal)

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Medical and Health Sciences - Basic Medicine - Immunology
  • Medical and Health Sciences - Basic Medicine - Medicinal Chemistry
  • Medical and Health Sciences - Health Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Spanish; Castilian Elementary (A2) Elementary (A2) Beginner (A1) Elementary (A2) Beginner (A1)
Education
Degree Classification
2022/09/20 - 2024/07/26
Concluded
Pharmacy (Mestrado)
Major in Pharmacotherapy and Pharmacoepidemiology
Instituto Politecnico do Porto Escola Superior de Tecnologia da Saúde do Porto, Portugal
""Preliminary study for the development of innovative pharmaceutical forms for the pediatric population"" (THESIS/DISSERTATION)
18
2019/09/13 - 2022/07/08
Concluded
Medicinal Chemistry (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Papel da ativação do mecanorrecetor Piezo-1 em células da microglia na neuro-inflamação" (THESIS/DISSERTATION)
14
Affiliation

Science

Category
Host institution
Employer
2025/05/01 - 2027/05/01 Researcher (Research) Instituto Politécnico de Leiria Centro de Inovação em Tecnologias e Cuidados de Saúde, Portugal
Instituto Politécnico de Leiria Centro de Inovação em Tecnologias e Cuidados de Saúde, Portugal

Others

Category
Host institution
Employer
2023/10/04 - 2024/03/29 Curricular Internship Instituto Politécnico de Leiria Centro de Inovação em Tecnologias e Cuidados de Saúde, Portugal
Instituto Politécnico de Leiria Escola Superior de Saúde, Portugal
2022/02/11 - 2022/07/08 Intern Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal
Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal
Projects

Contract

Designation Funders
2025/05/01 - Current MAP02 (Medication Adherence Platform 02/ Plataforma de adesão à medicação)
18485
Research Fellow
Instituto Politécnico de Leiria Escola Superior de Saúde, Portugal
Ongoing
Outputs

Publications

Conference abstract
  1. Castanheira, S.. "Innovative Oral Gummy Formulations for Pediatric Drug Administration: A Preliminary Study on Prednisolone and Deflazacort". Paper presented in Congresso Nacional dos Farmacêuticos 2024, Lisbon, 2024.
    Published
  2. Marisa da Costa Gaspar; Maria Pedro Sucena Guarino; ANA CRISTINA FERREIRA DE OLIVEIRA RODRIGUES; Solange Castanheira. Corresponding author: Marisa da Costa Gaspar. "Desenvolvimento de gomas saudáveis e sustentáveis: uma estratégia de valorização dos resíduos de maçã de Alcobaça". Paper presented in 7º Simpósio "Produção e Transformação de Alimentos em Ambiente Sustentável", Lisboa, 2024.
    Published
  3. Pinheiro, Rafael; Marisa da Costa Gaspar; Maria Pedro Sucena Guarino; ANA CRISTINA FERREIRA DE OLIVEIRA RODRIGUES. "FRUIGU - Fruit-based innovative gummies: a health-promoting and sustainable approach". Paper presented in 10 anos do Centro de Investigação da Unidade Local de Saúde da Região de Leiria, Leiria, 2024.
    Published
  4. solange8093@gmail.com ; Xavier Moreira, Fernando; Renata Duarte; Anabela Serafim. Corresponding author: solange8093@gmail.com. "Benefícios clínicos e analíticos evidenciados pelos Inibidores SGLT2 na Doença Renal Crónica: umbrella review [Clinical and analytical benefits of SGLT2 Inhibitors in Chronic Kidney Disease: umbrella review].". Paper presented in LusoSaúde- Jornadas Científicas da Saúde da Lusofonia, 2024.
    Published
Journal article
  1. Castanheira, Solange; Augusto, Ana; M. C. Gaspar; Guarino, MP. "Development and Characterization of Pediatric Prednisolone-Loaded Gummy Formulation: A Proof-of-Concept Study". International Journal of Pharmaceutics (2026):
    Open access • Submitted
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025/09/18 Medical Devices: Path To Certification and Compliance 5 o´clock
ciTechCare - Center for Innovative Care and Health Technology Mapa de ciTechCare - Center for Innovative Care and Health Technology Ver exterior ciTechCare - Center for Innovative Care and Health Technology (Leiria, Portugal)
2024/05/13 "Desenvolvimento de gomas saudáveis e sustentáveis: uma estratégia de valorização dos resíduos de maçã de Alcobaça" 10 anos do Centro de Investigação da Unidade Local de Saúde da Região de Leiria
Escola Superior de Saúde de Leiria (Leiria, Portugal)
2024/05/10 Study Visit to ciTechCare and Health Innovation Hub Course Unit “Introduction to the Profession” – Bachelor in Dietetics and Nutrition
Citechcare (Leiria, Portugal)
2024/04/13 FRUIGU - Fruit-based innovative gummies: a health-promoting and sustainable approach 5º aniversário do ciTechCare e a 1ª década do Centro de Investigação da Unidade Local de Saúde da Região de Leiria
Escola Superior de Saúde do Politécnico de Leiria (Leiria, Portugal)
2023/11/10 Benefícios clínicos e analíticos evidenciados pelos Inibidores SGLT2 na Doença Renal Crónica: umbrella review [Clinical and analytical benefits of SGLT2 Inhibitors in Chronic Kidney Disease: umbrella review] Scientific Program of the Lusophone Health Conference (LusoSaúde)
RACS Lusofonia (Portugal)

Event organisation

Event name
Type of event (Role)
Institution / Organization
2023/11/21 - 2023/11/21 Preparation and promotion of the activity "Let's make fruit go round? Healthy gum workshop", in line with the scientific program developed at ciTechCare as part of National Science and Technology Week. (2023/11/21 - 2023/11/21)
Workshop (Co-organisor)
Instituto Politécnico de Leiria Centro de Inovação em Tecnologias e Cuidados de Saúde, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2023/10/25 - Current Science Swing about "Advanced methods to delineate complex microbial communities towards clinical application"
Round table
Science Swing
Instituto Politécnico de Leiria Centro de Inovação em Tecnologias e Cuidados de Saúde, Portugal
2023/10/19 - Current Science Swing about " Sharing Research Experiences in Palliative Care ".
Round table
Science Swing
Instituto Politécnico de Leiria Centro de Inovação em Tecnologias e Cuidados de Saúde, Portugal
2026/03/11 - 2026/03/12 Participation in the International Advanced School “Frontiers on Additive Biomanufacturing for Biomedical Applications & Predictive Models”, held on 11–12 March 2026, at Centro Empresarial / CDRSP, Marinha Grande, Portugal. The event focused on recent advances in additive biomanufacturing, in vitro and in vivo models, advanced tissue engineering, and predictive modeling approaches in biomedical applications.
Conference
International Advanced School: Frontiers on Additive Biomanufacturing
Instituto Politécnico de Leiria Centro para o Desenvolvimento Rápido e Sustentado de Produto, Portugal
2025/12/04 - 2025/12/04 Participation in an online course on the application of Artificial Intelligence in the scientific research process, including concepts, ethics, and practical workflows for literature review using AI tools.
Workshop
Pesquisa científica na era da IA: do conceito ao workflow prático- L3 Soluções em Tecnologia LTDA (Even3).
2025/11/24 - 2025/11/30 The Science and Technology Week is a nacional initiative of Ciência Viva, which occurs every year, in november, in the scope of the National Day of Scientific Culture, on november 24, and intends to reveal national scientists, what they investigate and their contributions to the improvement of science and the well-being of society. During this week, all around the country, there will be hundreds of science and technology actions organized by scientific institutions, universities, schools, museums and science centers.
Other
Semana da Ciência e Tecnologia 2025
Instituto Politécnico de Leiria Centro de Inovação em Tecnologias e Cuidados de Saúde, Portugal
2025/11/27 - 2025/11/27 Designed and delivered a hands-on workshop entitled “Ciência com Sabor: Laboratório de Gomas Sustentáveis” for basic education students at Agrupamento de Escolas D. Dinis, within Ciência Viva – Science and Technology Week.
Workshop
Science and Technology Week (Ciência Viva)
Instituto Politécnico de Leiria Centro de Inovação em Tecnologias e Cuidados de Saúde, Portugal
2025/11/24 - 2025/11/26 Participação em formação sobre elaboração e implementação do Clinical Investigation Plan (CIP) para investigações clínicas de dispositivos médicos, em conformidade com o MDR (UE) 2017/745, ISO 14155:2020 e orientações do MDCG, no âmbito do Grupo de Trabalho promovido pela AICIB.
Workshop
"Dispositivos Médicos | Como Estruturar um Plano de Investigação Clínica"
Agência de Investigação Clínica e Inovação Biomédica, Portugal
2025/05/13 - 2025/05/13 6th Anniversary Session of ciTechCare – Center for Innovative Care and Health Technology
Other
6th Anniversary Session of ciTechCare – Center for Innovative Care and Health Technology
Instituto Politécnico de Leiria Centro de Inovação em Tecnologias e Cuidados de Saúde, Portugal
2024/11/21 - 2024/11/23 Congresso Nacional dos Farmacêuticos 2024
Congress
Congresso Nacional dos Farmacêuticos 2024
Ordem dos Farmaceuticos, Portugal
2024/04/29 - 2024/04/29 7º Simpósio "Produção e Transformação de Alimentos em Ambiente Sustentável"
Symposium
7º Simpósio "Produção e Transformação de Alimentos em Ambiente Sustentável"
Instituto Nacional de Investigação Agrária e Veterinária, Portugal
2024/02/19 - 2024/02/20 A course on the editorial selection process, indexes and categories of the Web of Science and information available on the Web of Science. Master Journal List.
Seminar
Clarivate Analytics UK Limited, United Kingdom
2024/01/19 - 2024/01/19 Science Swing about " Tackling disabilities with technology"
Round table
Science Swing
Instituto Politécnico de Leiria Centro de Inovação em Tecnologias e Cuidados de Saúde, Portugal
2023/12/12 - 2023/12/12 Analysis of the article 'A double-blind randomised controlled trial of protein supplementation to enhance exercise capacity in COPD during pulmonary rehabilitation: a pilot study' (DOI:10.1183/23120541.00077-2021).
Other
Journal Club on "COPD and nutrition"
Instituto Politécnico de Leiria Centro de Inovação em Tecnologias e Cuidados de Saúde, Portugal
2023/12/06 - 2023/12/06 Jornadas Healthy Campus do Politécnico de Leiria
Conference
Jornadas Healthy Campus do Politécnico de Leiria
Instituto Politécnico de Leiria, Portugal
2023/11/28 - 2023/11/28 Science Swing about "Unveiling words: Lexical/Morphological Processing and Speech Therapy"
Round table
Science Swing
Instituto Politécnico de Leiria Centro de Inovação em Tecnologias e Cuidados de Saúde, Portugal
2023/11/25 - 2023/11/25 The "XIX Colóquio de Farmácia" [XIX Pharmacy Colloquium"] aimed to deepen and discuss topics related to health, pharmacy and medicine. Its sessions were: "Current Challenges in Mental Health" and "Depression: Therapeutic Approaches to a Perennial Challenge in the Contemporary World".
Conference
XIX Colóquio de Farmácia
Instituto Politecnico do Porto Escola Superior de Tecnologia da Saúde do Porto, Portugal
2023/11/23 - 2023/11/23 Participation in the session "Health in motion: evaluation of capacity and physical activity", as part of Science and Technology Week 2023, held by ciTechCare- Center for Innovative Care and Health Technology.
Conference
"Health in motion: evaluation of capacity and physical activity"
Instituto Politécnico de Leiria Centro de Inovação em Tecnologias e Cuidados de Saúde, Portugal
2023/11/22 - 2023/11/22 Participation in the session "Bioimpedance - A discovery of body composition", as part of Science and Technology Week 2023, held by the ciTechCare- Center for Innovative Care and Health Technology.
Conference
Bioimpedance - A discovery of body composition
Instituto Politécnico de Leiria Centro de Inovação em Tecnologias e Cuidados de Saúde, Portugal
2023/11/21 - 2023/11/21 Participation in the session "Complementary feeding up to the age of 2: recommendations and challenges", as part of Science and Technology Week 2023, held by ciTechCare- Center for Innovative Care and Health Technology.
Conference
"Complementary feeding up to the age of 2: recommendations and challenges"
Instituto Politécnico de Leiria Centro de Inovação em Tecnologias e Cuidados de Saúde, Portugal
2023/11/20 - 2023/11/20 Participation in the session "How can science perceive our emotions?", as part of Science and Technology Week 2023, held by ciTechCare- Center for Innovative Care and Health Technology
Conference
"How can science perceive our emotions?"
Instituto Politécnico de Leiria Centro de Inovação em Tecnologias e Cuidados de Saúde, Portugal
2023/11/20 - 2023/11/20 Participation in the session "Is your favorite tea safe? - Interactions between plants and medicines", as part of Science and Technology Week 2023, held by ciTechCare- Center for Innovative Care and Health Technology.
Conference
"Is your favorite tea safe? - Interactions between plants and medicines"
Instituto Politécnico de Leiria Centro de Inovação em Tecnologias e Cuidados de Saúde, Portugal
2023/11/16 - 2023/11/18 The Farm to Fork congress was based on sharing knowledge, learning and networking opportunities between researchers, scientists, decision-makers, agri-food and nutrition professionals, students and representatives of the agri-food industry. Over the course of the three days, various lectures and workshops were held covering topics in the areas of Agri-Food, Nutrition and Sustainability, resulting in engaging and dynamic discussions that substantially enriched the overall quality of the event.
Congress
Farm to Fork
Associação Centro de Apoio Tecnológico Agro-Alimentar de Castelo Branco, Portugal
2023/10/17 - 2023/10/17 The Dietetics and Nutrition Conference aimed to "bring to debate some of the most current issues in nutrition, particularly in the areas of sports nutrition, food myths, pediatric nutrition, and intestinal health, seeking to make known the latest scientific evidence on these topics".
Conference
Dietetics and Nutrition Conference
Instituto Politécnico de Leiria Escola Superior de Saúde, Portugal
Distinctions

Award

2016 1st place - Cadet women - Regional indoor championship
2016 2nd place- Cadet women- V Neves de Carvalho tournament
2016 3rd place - Female Federated - Jumbo race
2015 Diploma of sporting merit
2015 1st place - Cross-country - Girls' beginners 1st place - Girls' cadets - APLisboa regional speed skating meet
2015 2nd place - Cadet women - Regional indoor championship
2015 2nd place- Cadet women-4th Neves de Carvalho tournament
2015 3rd place - Cadet women - National Road Championship - 3000mts Americana
2014 1st place- Girls' beginners- Skating skills 1st place- Girls' beginners- III APL indoor district meeting
2014 1st place - Women's beginners - 3rd Neves de Carvalho tournament
2014 3rd place - Women's beginners - National Road Championship - 3000mts Americana
2013 1st place - Girls' beginners - Skating skills
2013 2nd place - Women's beginners - 2nd Neves de Carvalho tournament
2013 2nd place - Women's beginners - II APL indoor district meeting
2013 2nd place - Girls' beginners - VI young skater's grand prix
2013 3rd place - Women's beginners - APLisboa District Meetings
2012 3rd place - Female children - 1st Neves de Carvalho Tournament
2012 3rd place- IV indoor skating and running meet
2010 3rd place school relay 2010

Title

2010 Competitive speed skater