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Ana Amaral has been working in animal reproduction since 2012, when she started a scientific scholarship at CIISA - FMV/UL under the supervision of Professor Graça Ferreira Dias. After, in 2015, Ana started her PhD studies conducted at CIISA and at PAS, Olsztyn, Poland, under the supervision of Professor Graça Ferreira Dias and Professor Dariusz Skarzysnski. The PhD investigation and thesis were focused on the effect of proteases (such as elastase, cathepsin G and myeloperoxidase) present in neutrophil extracellular traps (NETs) and their pro-fibrotic effect in equine endometrium. Moreover, she also investigated the effect of some protease inhibitors found in NETs to evaluate if their inhibition would reduce their pro-fibrotic action. Thus, this would thereby open new opportunities for future development of specific drugs to be used as prophylaxis or therapy of endometrosis in the mare. Ana successfully defended her PhD thesis in January 2021 and was awarded two prizes for the work presented as two oral communications during the PhD - at the Annual Meeting of the Portuguese Association of Veterinary Doctors in 2018 and in 2019. Further, Ana also was the recipient of a CIISA-FMV/UL project, as a principal investigator. This allowed her to finish her PhD studies and resulted in the publication of two articles as first author. In 2019-2020, Ana accepted a position as Invited Assistant Professor at Escola Superior Agrária de Elvas (Elvas, Portugal) where she delivered lectures of Anatomy, Physiology and Emergency and hospital care in Veterinary Nursing degree. From 2020 to 2022, Ana joined the team of the Faculty of Veterinary Medicine of Universidade Lusófona de Humanidades e Tecnologias (Lisbon, Portugal) where she coordinated and was a lecturer of Equine Reproduction, Gynecology and Obstetrics, Physiology and Equine Neonatology, which are curricular units of the Integrated Master´s of Veterinary Medicine degree. Ana Amaral was also a member of Ethics and Animal Welfare Commission at this institution. Between 2022-2023, Ana was an Assistant Porfessor at University of Évora teaching Physiology, Anatomy and Exognosis. Since 2023, Ana started a position as Assistant Professor at Faculty of Veterinary Medicine University of Lisbon. Ana has published 19 manuscripts in international journals with peer review (11 of them in quartile 1 journals), (7 of them as first author), 1 book chapter with peer review, 16 international oral communications (5 of them as a first author), 20 national oral communications (7 of them as a first author), 17 international poster presentations (5 of them as a first author), and 10 national poster presentations (3 of them as a first author). According to Scopus her scientific metric data are 19 documents, 178 citations and a h-index of 8. Ana has also attend to many external courses related to equine reproduction and in-house seminars mainly to improve teaching skills. As an academic advisor, she supervised 6 students.
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Identification

Personal identification

Full name
Ana Sofia Pires Amaral

Citation names

  • Amaral, Ana

Author identifiers

Ciência ID
EB18-9420-421B
ORCID iD
0000-0002-0075-262X
Scopus Author Id
56394000500

Knowledge fields

  • Agrarian Sciences - Veterinary Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Spanish; Castilian Intermediate (B1) Upper intermediate (B2) Intermediate (B1) Upper intermediate (B2) Intermediate (B1)
Education
Degree Classification
2015/09/01 - 2021/01/20
Concluded
 Ciências Veterinárias (Doutoramento)
Major in Especialidade: Ciências Biológicas e Biomédicas
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
"New insights on the inhibition of neutrophil extracellular traps enzymes in equine endometrium " (THESIS/DISSERTATION)
 Aprovado com distinção e louvor
2018 - 2018
Concluded
 Veterinary Acupuncture postgraduate (Pós-Graduação)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
 Excellent
2004/09/01 - 2010/07/16
Concluded
 Medicina Veterinária (Mestrado integrado)
Universidade de Évora, Portugal
 15
Affiliation

Science

Category
Host institution 		Employer
2021/02/01 - Current Postdoc (Research) Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
2012/07/01 - 2015/08/31 Researcher (Research) Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2023/12 - Current Assistant Professor (University Teacher) Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
2022/12 - 2023/12 Assistant Professor (University Teacher) Universidade de Évora, Portugal
2020/10/01 - 2022/12 Assistant Professor (University Teacher) Universidade Lusófona de Humanidades e Tecnologias, Portugal
2019/09/01 - 2020/09/30 Invited Assistant (Polytechnic Teacher) Instituto Politécnico de Portalegre Escola Superior Agrária de Elvas, Portugal

Other Careers

Category
Host institution 		Employer
2011 - 2012 Técnico Superior (Técnico Superior) VetCentro, Portugal
2010 - 2012 Técnico Superior (Técnico Superior) Animal Care, Portugal

Others

Category
Host institution 		Employer
2015/09/01 - 2020/08/31 Phd Student Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
Projects

Grant

Designation Funders
2023/03/01 - Current Role of TGFß in the pro-fibrotic action of NETs enzymes as a potential target of a therapeutic strategy in mare endometrosis
2022.07400.PTDC
Principal investigator
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2023/02/01 - Current Epigenetic Modifications in the Mare Endometrium: Implications in the Pathogenesis of Fibrosis in Endometrosis
2022.09161.PTDC
Researcher
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2021/01/01 - 2021/12/31 Noscapine inhibition of pro-fibrotic effects of enzymes found in neutrophil extracellular traps in equine endometrium
UID/CVT/00276/2013
Principal investigator
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
Concluded
2015/09/01 - 2020/08/31 How to Solve infertility: Is fighting Neutrophil Extracellular Traps, Cytokines or Prostaglandins a Solution?
PTDC/CVT-REP/4202/2014
PhD Student Fellow
Concluded
2015/11 - 2018/10 How to solve infertility: Is fighting neutrophil extracellular traps, cytokines or prostaglandins a solution?
Provided by PTCRIS: 142833
PTDC/CVT-REP/4202/2014
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2015 - 2016 Neutrophil Extracellular Traps, cytokines and prostaglandins: are they a threat for equine endometrium fibrosis?
Projecto nº 6818
PhD Student Fellow
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal

Instytut Rozrodu Zwierzat i Badan Zywnosci Polskiej Akademii Nauk w Olsztynie, Poland
2012/01 - 2015/08 Neutrophil extracellular traps and cytokines in the endometrium: Friends or Foes?
Provided by PTCRIS: 121805
PTDC/CVT/121805/2010
 Fundação para a Ciência e a Tecnologia
2013 - 2014 Transforming Growth Factor Beta Superfamily in the physiopathology of mare endometrium and ovary
Projecto nº 13789
Research Fellow
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal

Instytut Rozrodu Zwierzat i Badan Zywnosci Polskiej Akademii Nauk w Olsztynie, Poland
Concluded

Contract

Designation Funders
2023/05/01 - 2024/10/31 PARs and TLRs as potential biomarkers and targets of a therapeutic strategy in mare endometrosis
AL4A-PROJ-LT3.7
Principal investigator
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal

Al4AnimalS, Portugal
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal

Al4AnimalS
Ongoing
Outputs

Publications

Book chapter
  1. Ferreira-Dias, G.; Rebordão, M. R.; Galvão, A. M.; Roberto-da-Costa, R.; Amaral, A.; Fernandes, C.; Pinto-Bravo, P.; et al. Corresponding author: Ferreira-Dias, G.. "What Goes Wrong from a Mare Healthy Endometrium to Endometrosis?". In Advances in Animal Health, Medicine and Production, 528-540. Springer International Publishing, 2020.
    10.1007/978-3-030-61981-7_29
Conference abstract
  1. Marta Cerveira Pinto; Rebordão MR; Kordowitzki P; Skarzynski DJ; Ferreira-Dias, Graça; Szóstek-Miouduchowska A; Amaral, Ana. "Efeito do TGFß1 e da progesterona na expressão de colagénio em explantes de endométrio equino da fase lútea". Paper presented in VIIas Jornadas do Grupo de Trabalho de Investigação em Equídeos – GTIE, Lisboa, 2023.
    Published
  2. Figueiredo F; Borges P; Lopes AS; Amaral, Ana; Alves M. "Herpesvírus canino tipo 1: como gerir animais infetados em coletividades?". Paper presented in XIX Montenegro International Veterinary Congress - The Next Decade Without Secrets XIX Medicine Congress, Santa Maria da Feira, 2023.
    Published
  3. Palha G; Belas A; Fonseca J; Catarino J; Alves M; Amaral, Ana; Borges P; Serafim MKB. "Endometrite em cadelas clinicamente saudáveis – in vivo". Paper presented in XIX Montenegro International Veterinary Congress - The Next Decade Without Secrets XIX Medicine Congress, Santa Maria da Feira, 2023.
    Published
  4. Amaral, Ana; Anna Szóstek-Mioduchowska; Maria Rosa Rebordão; Marta Cerveira Pinto; Cebola, Nélio; Dariusz Skarzynski; Ferreira-Dias, Graça. "Estradiol could prevent the production of fibrogenic PGF2a in an acute response to TGFß1 in equine endometrium during follicular phase". Paper presented in 1st European Symposium on Animal Reproduction, Nantes, 2023.
    Published
  5. Amaral, Ana; Rebordão MR; Fernandes C; Szóstek-Miouduchowska A; Lukasik K; Skarzynski DJ; Ferreira-Dias, Graça. "EFEITO ANTI-FIBRÓTICO DO ESTRADIOL DURANTE A FASE FOLICULAR PODERÁ PREVENIR O DESENVOLVIMENTO DE ENDOMETROSE EQUINA INDUZIDA PELO TGFß1". Paper presented in 10º Encontro de Formação da Ordem dos Médicos Veterinários, Lisboa, 2023.
    Published
  6. Ferreira, G. G. S.; Amaral, Ana; Serafim, M. K. B.. "IMPACTO DA PANDEMIA CAUSADA POR COVID-19 NOS CENTROS DE ATENDIMENTO MÉDICO VETERINÁRIOS EM PORTUGAL – APÓS PRIMEIRO PERÍODO DE CONFINAMENTO EM 2020". Paper presented in 10º Encontro de Formação da Ordem dos Médicos Veterinários, Lisboa, 2023.
    Published
Conference paper
  1. Pinto-Bravo P; Rebordão MR; Amaral A; Fernandes C; Cuello C; Parrila I; Martinez E; et al. Corresponding author: Ferreira-Dias, Graça. "Oviduct fibrosis in mares with endometrosis: is it a myth or a fact?". Paper presented in 10th International Conference on Equine Reproductive Medicine (ICERM), Leipzig, 2018.
    Published
  2. Rebordão MR; Amaral A; Galvão A; Szóstek A; Pinto-Bravo P; Skarzynski DJ; Ferreira-Dias G. "Hormones role on mare reproductive physiology and dysfunction.". Paper presented in 9th International Conference on Equine Reproductive Medicine (ICERM), Leipzig, 2016.
    Published
Conference poster
  1. Cerveira Pinto M; Rebordão MR; Kordowitzki P; Skarzynski DJ; Ferreira-Dias, Graça; Szóstek-Miouduchowska A; Amaral, Ana. "Efeito do TGFß1 e da progesterona na expressão de colagénio em explantes de endométrio equino da fase lútea". Paper presented in VIIas Jornadas do Grupo de Trabalho de Investigação em Equídeos - GTIE, 2023.
  2. M. Cerveira Pinto; A. Wójtowicz; M. A. Pires; Ferreira-Dias, G.; D. J. Skarzynski; Szóstek-Mioduchowska, A.; Amaral, Ana. "mRNA expression of PARs and TLRs in equine endometrium varies with histopathological lesions and the estrous cycle phase". Paper presented in Al4AnimalS Comparative and Translational Medicine and Biotechnology - ICBAS, 2023.
  3. Figueiredo F; Borges P; Lopes AS; Amaral, Ana; Alves M. "Herpesvírus canino tipo 1: como gerir animais infetados em coletividades?". Paper presented in XIX Montenegro International Veterinary Congress - The Next Decade Without Secrets XIX Medicine Congress, 2023.
  4. Palha G; Belas A; Fonseca J; Catarino J; Alves M; Amaral, Ana; Borges P; Serafim MKB. "Endometrite em cadelas clinicamente saudáveis – in vivo". Paper presented in XIX Montenegro International Veterinary Congress - The Next Decade Without Secrets XIX Medicine Congress, 2023.
  5. Ferreira, G. G. S.; Amaral, Ana; Serafim, M. K. B.. "IMPACTO DA PANDEMIA CAUSADA POR COVID-19 NOS CENTROS DE ATENDIMENTO MÉDICO VETERINÁRIOS EM PORTUGAL – APÓS PRIMEIRO PERÍODO DE CONFINAMENTO EM 2020". Paper presented in 10º Encontro de Formação da Ordem dos Médicos Veterinários, 2023.
  6. Francisca Figueiredo; Paulo Borges; Ana Sousa Lopes; Amaral, Ana; Margarida Alves. "Molecular detection of canine herpesvirus in the reproductive tract of the bitch in different stages of the estrous cycle". Paper presented in CIISA congress 2022, 2022.
  7. Amaral, Ana; Carina Fernandes; Cebola, Nélio Galrito; Maria Rosa Rebordão; Anna Szóstek-Mioduchowska; Dariusz Jan Skarzynski; Ferreira-Dias, Graça. "The use of selective inhibitors of NETs enzymes may reduce endometrosis development in the mare". Paper presented in 16º Congreso Internacional de AERA2022, 2022.
  8. Amaral A; Fernandes C; Lukasik K; Szóstek-Mioduchowska A; Rebordão MR; Morazzo S; Pinto-Bravo P; Skarzynski DJ; Ferreira-Dias G. Corresponding author: Ferreira-Dias G. "Inhibitory effect of noscapine on cathepsin-induced collagen production and prostaglandin secretion in mare endometrium". Paper presented in 15º Congreso Internacional de la Asociación Española de Reproducción Animal, 2019.
  9. Alpoim-Moreira J; Fernandes C; Rebordão MR; Amaral A; Pinto-Bravo P; Morazzo S; Bliebernicht M; Skarzynski DJ; Ferreira-Dias G. Corresponding author: Ferreira-Dias G. "Putative blood biomarkers of fibrosis in equine endometrium". Paper presented in 15º Congreso Internacional de la Asociación Española de Reproducción Animal, 2019.
  10. Amaral A; Fernandes C; Lukasik K; Morazzo S; Rebordão MR; Pinto-Bravo P; Skarzynski DJ; Ferreira-Dias G. "Noscapine inhibits collagen deposition induced by neutrophil extracellular traps components in equine endometrium". Paper presented in 23rd Annual meeting ESDAR, 2019.
  11. Pinto-Bravo P; Amaral A; Rebordão MR; Fernandes C; Morazzo S; Alpoim-Moreira J; Roberto da Costa R; Skarzynski D; Ferreira-Dias G. Corresponding author: Ferreira-Dias G. "A transcrição de colagénio no oviduto equino e possíveis vias envolvidas". Paper presented in 9º Encontro de Formação da Ordem dos Médicos Veterinários, 2019.
  12. Amaral A; Fernandes C; Lukasik ; Szóstek-Mioduchowska A; Baclawska A; Morazzo S; Rebordão MR; et al. Corresponding author: Ferreira-Dias G. "Evaluation of elastase and cathepsin G inhibition on collagen transcription and prostaglandin secretion in mare endometrium". Paper presented in III PhD Meeting in Environment and Agriculture, 2018.
  13. Amaral A; Fernandes C; Lukasik K; Szóstek-Mioduchowska A; Rebordão MR; Baclawska A; Morazzo S; et al. Corresponding author: Ferreira-Dias G. "Sivelestat and noscapine modulate collagen transcription and prostaglandin secretion in mare endometrium". Paper presented in Exploring the boundaries of animal, veterinary and biomedical sciences, 2018.
  14. Morazzo S; Amaral A; Galvão A; Rebordão MR; Skarzynski DJ; Ferreira-Dias G. "Nodal protein expression in mare’s endometrium". Paper presented in 22nd Annual ESDAR Conference 2018, 2018.
  15. Amaral A; Fernandes C; Lukasik K; Szóstek-Mioduchowska A; Rebordão MR; Morazzo S; Pinto-Bravo P; Skarzynski DJ; Ferreira-Dias G. Corresponding author: Ferreira-Dias G. "Noscapine inhibits elastase induced collagen transcription and prostaglandin secretion in mare endometrium". Paper presented in 2nd International Conference on Tissue Repair, Regeneration, and Fibrosis, 2018.
  16. Rebordão MR; Amaral A; Fernandes C; Lukasik K; Szóstek-Mioduchowska A; Galvão A; Pinto-Bravo P; Skarzynski DJ; Ferreira-Dias G. Corresponding author: Ferreira-Dias G. "Prostaglandin environment may favor collagen deposition in mare endometrium when challenged by neutrophil extracellular traps proteases". Paper presented in 2nd International Conference on Tissue Repair, Regeneration, and Fibrosis, 2018.
  17. Amaral A; Fernandes C; Lukasik K; Rebordão MR; Pinto-Bravo P; Skarzynski DJ; Ferreira-Dias G. Corresponding author: Ferreira-Dias G. "Efeito da inibição in vitro da catepsina na transcrição do colagénio 1 e 3 e na função secretora do endométrio equino". Paper presented in V Jornadas do Grupo de Trabalho de Investigação em Equídeos., 2017.
  18. Amaral A; Rebordão MR; Pinto-Bravo P; Lukasik K; Galvão A; Skarzynski DJ; Ferreira-Dias G. Corresponding author: Ferreira-Dias G. "Inhibition of NETs components on collagen 1 and 3 transcription on in mare endometrium". Paper presented in 20th Annual meeting ESDAR – 13th Congress AERA, 2016.
  19. Rebordão MR; Amaral A; Lukasik K; Szóstek A; Galvão A; Pinto-Bravo P; Skarzynski DJ; Ferreira-Dias G. Corresponding author: Ferreira-Dias G. "Neutrophil extracellular traps components and mare endometrium fibrosis: are they related?". Paper presented in 1rst International Conference on Tissue Repair, Regeneration and Fibrosis, 2016.
  20. Volpi A; Rebordão MR; Amaral A; Galvão A; Pinto Bravo P; Mollo A; Ferreira-Dias G. "Nodal and its receptors ALK-4 and ALK-7 in healthy and fibrotic endometrium of cyclic mare.". Paper presented in 18th Conference of European society for Domestic Animal Reproduction, 2014.
  21. Pinto Bravo P; Amaral A; Galvão A; Rebordão MR; Silva E; Roberto da Costa RP; Ferreira-Dias G. Corresponding author: Ferreira-Dias G. "Transcription of VEGF, FGF1 and 2 and their receptors in different portions of the equine oviduct along the estrous cycle". Paper presented in 18th Conference of European society for Domestic Animal Reproduction, 2014.
  22. Alexandre-Pires G; Martins C; Galvão M; Amaral A; Ferreira Dias G. Corresponding author: Ferreira Dias G. "About the inguinal gland during gestation and after parturition: a glance towards prolactin, estradiol and progesterone receptors". Paper presented in Congress of the European Association of Veterinary Anatomists, 2014.
  23. Saavedra MJ; Dias C; Amaral A; Branco S; Queiroga MC. Corresponding author: Queiroga MC. "Fatores de virulência em Aeromonas hydrophila causadora de septicémia em leitões". Paper presented in VI Congresso da SPCV, 2014.
  24. Rebordão MR; Galvão A; Amaral A; Szóstek A; Lukasik K; Piotrowska-Tomala K; Skarzynski DJ; Ferreira-Dias G. Corresponding author: Ferreira-Dias G. "Estrous cycle phases on mare endometrium secretory function and fibrosis markers (TIMP 1 and TGFß1) after neutrophil extracellular traps and cytokines action". Paper presented in 17th Conference of European society for Domestic Animal Reproduction, 2013.
  25. Galvão A; Amaral A; Pinto Bravo P; Rebordão MR; Szostek A; Skarzynski D; Ferreira-Dias G. "Nodal signaling pathway supports luteolysis via Tumor necrosis factor in equine corpus luteum.". Paper presented in 17th Conference of European Society for Domestic Animal Reproduction, 2013.
Journal article
  1. Ana Amaral; Nélio Cebola; Anna Szóstek-Mioduchowska; M.R. Rebordao; Pawel KORDOWITZKI; Dariusz J. SKARZYNSKI; G Ferreira-Dias. "Inhibition of Myeloperoxidase Pro-Fibrotic Effect by Noscapine in Equine Endometrium". International Journal of Molecular Sciences (2023): https://www.mdpi.com/1422-0067/24/4/3593.
    10.3390/ijms24043593
  2. Ana Amaral; Carina Fernandes; Anna Szóstek-Mioduchowska; Karolina Lukasik; Maria Rosa Rebordão; Pedro Pinto-Bravo; Dariusz Jan Skarzynski; Graça Ferreira-Dias. "The Inhibitory Effect of Noscapine on the In Vitro Cathepsin G-Induced Collagen Expression in Equine Endometrium". Life 11 10 (2021): 1107-1107. https://doi.org/10.3390/life11101107.
    10.3390/life11101107
  3. Maria Rosa Rebordão; Ana Amaral; Carina Fernandes; Elisabete Silva; Karolina Lukasik; Anna Szóstek-Mioduchowska; Pedro Pinto-Bravo; et al. "Enzymes Present in Neutrophil Extracellular Traps May Stimulate the Fibrogenic PGF2a Pathway in the Mare Endometrium". Animals 11 9 (2021): 2615-2615. https://doi.org/10.3390/ani11092615.
    10.3390/ani11092615
  4. Ana Amaral; Carina Fernandes; Anna Szóstek-Mioduchowska; Maria Rosa Rebordão; Dariusz Jan Skarzynski; Graça Ferreira-Dias. "Noscapine Acts as a Protease Inhibitor of In Vitro Elastase-Induced Collagen Deposition in Equine Endometrium". International Journal of Molecular Sciences 22 10 (2021): 5333-5333. https://doi.org/10.3390/ijms22105333.
    10.3390/ijms22105333
  5. Pedro Pinto-Bravo; Maria Rosa Rebordão; Ana Amaral; Carina Fernandes; António Galvão; Elisabete Silva; Pedro Pessa-Santos; et al. "Microvascularization and Expression of Fibroblast Growth Factor and Vascular Endothelial Growth Factor and Their Receptors in the Mare Oviduct". Animals 11 4 (2021): 1099-1099. https://doi.org/10.3390/ani11041099.
    10.3390/ani11041099
  6. Ana Amaral; Carina Fernandes; Maria Rosa Rebordão; Anna Szóstek-Mioduchowska; Karolina Lukasik; Pedro Pinto-Bravo; Luís Telo da Gama; Dariusz Jan Skarzynski; Graça Ferreira-Dias. "Myeloperoxidase Inhibition Decreases the Expression of Collagen and Metallopeptidase in Mare Endometria under In Vitro Conditions". Animals (2021): https://doi.org/10.3390/ani11010208.
    10.3390/ani11010208
  7. Amaral, Ana; Fernandes, Carina; Morazzo, Sofia; Rebordão, Maria Rosa; Szóstek-Mioduchowska, Anna; Lukasik, Karolina; Gawronska-Kozak, Barbara; et al. "The Inhibition of Cathepsin G on Endometrial Explants With Endometrosis in the Mare". Frontiers in Veterinary Science 7 (2020): http://dx.doi.org/10.3389/fvets.2020.582211.
    10.3389/fvets.2020.582211
  8. Ana Amaral; Carina Fernandes; Maria Rosa Rebordão; Anna Szóstek-Mioduchowska; Karolina Lukasik; Barbara Gawronska-Kozak; Luís Telo da Gama; Dariusz J. Skarzynski; Graça Ferreira-Dias. "The In Vitro Inhibitory Effect of Sivelestat on Elastase Induced Collagen and Metallopeptidase Expression in Equine Endometrium". Animals 10 5 (2020): 863-863. https://doi.org/10.3390/ani10050863.
    10.3390/ani10050863
  9. Joana Alpoim-Moreira; Carina Fernandes; Maria Rosa Rebordão; Ana Amaral; Pedro Pinto-Bravo; Miguel Bliebernicht; Dariusz J. Skarzynski; Graça Ferreira-Dias. "Collagens and DNA methyltransferases in mare endometrosis". Reproduction in Domestic Animals 54 (2019): 46-52. https://doi.org/10.1111/rda.13515.
    10.1111/rda.13515
  10. Rebordão, Maria Rosa; Amaral, Ana; Lukasik, Karolina; Szóstek-Mioduchowska, Anna; Pinto-Bravo, Pedro; Galvão, António; Skarzynski, Dariusz J.; Ferreira-Dias, Graça. "Impairment of the antifibrotic prostaglandin E2 pathway may influence neutrophil extracellular traps–induced fibrosis in the mare endometrium". Domestic Animal Endocrinology 67 (2019): 1-10. http://dx.doi.org/10.1016/j.domaniend.2018.10.004.
    10.1016/j.domaniend.2018.10.004
  11. Amaral, Ana; Fernandes, Carina; Lukasik, Karolina; Szóstek-Mioduchowska, Anna; Baclawska, Agnieszka; Rebordão, Maria Rosa; Aguiar-Silva, Joana; et al. "Elastase inhibition affects collagen transcription and prostaglandin secretion in mare endometrium during the estrous cycle". Reproduction in Domestic Animals 53 (2018): 66-69. http://dx.doi.org/10.1111/rda.13258.
    10.1111/rda.13258
  12. Rebordão, Maria Rosa; Amaral, Ana; Lukasik, Karolina; Szóstek-Mioduchowska, Anna; Pinto-Bravo, Pedro; Galvão, António; Skarzynski, Dariusz J.; Ferreira-Dias, Graça. "Constituents of neutrophil extracellular traps induce in vitro collagen formation in mare endometrium". Theriogenology 113 (2018): 8-18. http://dx.doi.org/10.1016/j.theriogenology.2018.02.001.
    10.1016/j.theriogenology.2018.02.001
  13. Pinto-Bravo, P; Ferreira-Dias, G; Rebordão, M R; Amaral, A; Fernandes, C; Cuello, C; Parrilla, I; et al. "Is mare endometrosis linked to oviduct fibrosis?". Pferdeheilkunde Equine Medicine 34 1 (2018): 43-46. http://dx.doi.org/10.21836/pem20180107.
    10.21836/pem20180107
  14. Pinto-Bravo, P.; Galvão, A.; Rebordão, M.R.; Amaral, A.; Ramilo, D.; Silva, E.; Szóstek-Mioduchowska, A.; et al. "Ovarian steroids, oxytocin, and tumor necrosis factor modulate equine oviduct function". Domestic Animal Endocrinology 61 (2017): 84-99. http://dx.doi.org/10.1016/j.domaniend.2017.06.005.
    10.1016/j.domaniend.2017.06.005
  15. Rebordão, M R; Amaral, A; Galvão, A; Szótek, A Z; Pinto-Bravo, P; Skarzynski, D S; Ferreira-Dias, G. "Dual effect of hormones on mare reproductive physiology and dysfunction". Pferdeheilkunde Equine Medicine 32 1 (2016): 36-38. http://dx.doi.org/10.21836/pem20160106.
    10.21836/pem20160106
  16. Rebordão, MR; Galvão, A; Szóstek, A; Amaral, A; Mateus, L; Skarzynski, DJ; Ferreira-Dias, G. "Physiopathologic Mechanisms Involved in Mare Endometrosis". Reproduction in Domestic Animals 49 (2014): 82-87. http://dx.doi.org/10.1111/rda.12397.
    10.1111/rda.12397
  17. Galvão, A.; Amaral, A.; Rebordão, M.; Bravo, P.; Lukasik, K.; Szóstek, A.; Skarzynski, D.; Ferreira-Dias, G.. "Novel luteolytic mechanisms in equine corpora lutea: the role of Nodal signaling pathway and its interaction with Tumor necrosis factor alpha, Interferon gamma and Fas ligand". Journal of Equine Veterinary Science 34 1 (2014): 117-119. http://dx.doi.org/10.1016/j.jevs.2013.10.080.
    10.1016/j.jevs.2013.10.080
  18. Galvão, António; Tramontano, Angela; Rebordão, Maria Rosa; Amaral, Ana; Bravo, Pedro Pinto; Szóstek, Anna; Skarzynski, Dariusz; Mollo, Antonio; Ferreira-Dias, Graça. "Opposing Roles of Leptin and Ghrelin in the Equine Corpus Luteum Regulation: AnIn VitroStudy". Mediators of Inflammation 2014 (2014): 1-13. http://dx.doi.org/10.1155/2014/682193.
    10.1155/2014/682193
  19. Queiroga, M. C.; Amaral, A. S. P.; Branco, S. M.. "Short communication. Isolation of Aeromonas hydrophila in piglets". Spanish Journal of Agricultural Research 10 2 (2012): 383. http://dx.doi.org/10.5424/sjar/2012102-495-11.
    10.5424/sjar/2012102-495-11
Thesis / Dissertation
  1. Amaral, Ana Sofia Pires. "New insights on the inhibition of neutrophil extracellular traps enzymes in equine endometrium". PhD, 2021. http://hdl.handle.net/10400.5/21012.
  2. Amaral, Ana Sofia Pires. "Relatório de estágio de clínica e cirurgia de animais de companhia: relatório de estágio de dominio fundamental". Master, 2010. http://hdl.handle.net/10174/12022.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/09/22 Estradiol could prevent the production of fibrogenic PGF2a in an acute response to TGFß1 in equine endometrium during follicular phase 1st European Symposium on Animal Reproduction
European Society for Animal Reproduction - ESDAR (Nantes, France)
2023/04/14 EFEITO ANTI-FIBRÓTICO DO ESTRADIOL DURANTE A FASE FOLICULAR PODERÁ PREVENIR O DESENVOLVIMENTO DE ENDOMETROSE EQUINA INDUZIDA PELO TGFß1 10º Encontro de Formação da Ordem dos Médicos Veterinários
Ordem dos Médicos Veterinários (Lisboa, Portugal)
2022/10/20 The use of selective inhibitors of NETs enzymes may reduce endometrosis development in the mare. 16º Congreso Internacional de AERA2022
AERA (Léon, Spain)
2022/03/11 Efeito da inibição da elastase pela noscapina na expressão de colagénio e metaloproteinases no endométrio equino 13ªs Jornadas do Hospital Veterinário Muralha de Évora
Hospital Veterinário Muralha de Évora (Évora, Portugal)
2019/11/07 Eficácia in vitro da noscapina na redução da formação de colagénio induzido por proteases das redes extracelulares dos neutrófilos no endométrio equino. V Jornadas do Grupo de Trabalho de Investigação em Equídeos. Panorama de Investigação em Equinos em Portugal
(Golegã, Portugal)
2019/11/07 Epigenética na endometrose equina V Jornadas do Grupo de Trabalho de Investigação em Equídeos. Panorama de Investigação em Equinos em Portugal.
(Golegã, Portugal)
2019/10/07 Poderá o endométrio refletir a fibrose existente no oviduto da égua? V Jornadas do Grupo de Trabalho de Investigação em Equídeos. Panorama de Investigação em Equinos em Portugal
(Golegã, Portugal)
2019/09 Possible link between equine oviduct glycoprotein expression and angiogenic players 23nd Annual meeting ESDAR
(São Petersburgo, Russia)
2019/04/06 Inibição in vitro da acção pro-fibrótica da elastase e da catepsina pela noscapina no endométrio equino 9º Encontro de Formação da Ordem dos Médicos Veterinários.
(Lisboa, Portugal)
2018/11/17 Sivelestat and noscapine modulate collagen transcription and prostaglandin secretion in mare endometrium. Exploring the boundaries of animal, veterinary and biomedical sciences
CIISA (Lisboa, Portugal)
2018/10 Evaluation of elastase and cathepsin G inhibition on collagen transcription and prostaglandin secretion in mare endometrium. III PhD Meeting in Environment and Agriculture
(Évora, Portugal)
2018/09 Elastase inhibition affects collagen transcription and prostaglandin secretion in mare endometrium during the estrous cycle. 22nd Annual meeting ESDAR. Reproduction in Domestic Animals.
(Córdoba, Spain)
2018/09 Fibrosis in donkey endometrium: how can we interpret it? 22nd Annual meeting ESDAR.
(Córdoba, Spain)
2018/09 DNA methylation in equine endometrium with different degrees of fibrosis. 22nd Annual meeting ESDAR
(Córdoba, Spain)
2018/04 Avaliação da função secretora e transcrição de colagénio pela inibição da catepsina in vitro no endométrio equino 8º Encontro de Formação da Ordem dos Médicos Veterinários
(Lisboa, Portugal)
2018/01/20 Oviduct fibrosis in mares with endometrosis: is it a myth or a fact? 10th International Conference on Equine Reproductive Medicine (ICERM)
ICERM (Leipzig, Germany)
2018/01/19 Is oviduct fibrosis linked to mare endometrosis? 9th Leipzig Expertworkshop on Equine Reproductive Medicine. “The role of the veterinarian in equine assisted reproductive technologies
ICERM (Leipzig, Germany)
2017/11/08 A transcrição e a expressão proteica da oviductina ao longo do ciclo éstrico da égua. V Jornadas do Grupo de Trabalho de Investigação em Equídeos.
(Golegã, Portugal)
2017/11/08 Possível envolvimento das prostaglandinas nos mecanismos fisiológicos contra a endometrose V Jornadas do Grupo de Trabalho de Investigação em Equídeos.
(Golegã, Portugal)
2017/11/08 A Endometrose da Égua e o Potencial Envolvimento do Nodal. V Jornadas do Grupo de Trabalho de Investigação em Equídeos.
(Golegã, Portugal)
2017/11 Possible factors involved in collagen deposition in equine oviduct 14º Congreso Internacional AERA
(Barcelona, Spain)
2017/09 The intricacies of mare endometrosis- how far have we gone? 3rd Conference “Endometritis as a cause of infertility in domestic animals
(Leipzig, Germany)
2017/09 Cathepsin inhibition affects mare endometrium prostaglandin secretion during the estrous cycle. 3rd Conference”Endometritis as a Cause of Infertility in Domestic Animals”.
(Olsztyn, Poland)
2017/09 Are mares physiologically protected against endometrial fibrosis induced by NETs proteases? 3rd Conference”Endometritis as a Cause of Infertility in Domestic Animals”
(Olsztyn, Poland)
2016/10 Mare endometrosis is dependent on estrous cycle cytokine environment. 20th Annual meeting ESDAR – 13th Congress AERA
(Lisboa, Portugal)
2016/01/16 Hormones role on mare reproductive physiology and dysfunction ICERM
(Leipzig, Germany)
2015/11/11 Podem as citocinas (PDGF, TGF-B1, CTGF e TNF) influenciar o desenvolvimento de fibrose no endométrio da égua? IV Jornadas do Grupo de Trabalho de Investigação em Equídeos.
(Golegã, Portugal)
2015/11/11 A vascularização e alguns factores angiogénicos no oviduto da égua. IV Jornadas do Grupo de Trabalho de Investigação em Equídeos.
(Golegã, Portugal)
2015/09 Neutrophil extracellular traps, cytokines and matrix metalloproteinases: players in mare endometrosis? 19th ESDAR conference.
(Albena, Bulgaria)
2015/01/15 New markers of mare oviductal function? 8th Leipzig Expertworkshop on Equine Reproduction
(Leipzig, Germany)
2014/10 Physiopathologic mechanisms involved in mare endometrosis 12º Congreso Internacional de la Asociación Española de Reproducción Animal (AERA)
(Alicante, Spain)
2014/09 Neutrophil extracellular traps and CTGF on the expression of prostaglandin receptors genes in mare endometrosis 18th Conference of European society for Domestic Animal Reproduction.
(Helsínquia, Finland)
2014/04 Expressão do mRNA de Nodal e seus receptores ALK-4 e ALK-7 no estabelecimento da fibrose no endométrio da égua cíclica VI Congresso da SPCV.
(Oeiras, Portugal)
2014/04 A possível influência do TNFa na funcionalidade do oviduto equino. VI Congresso da SPCV.
(Oeiras, Portugal)
2014/01/17 Mare oviduct: ovarian steroids, oxytocin and TNF¿ on prostaglandins secretory function 8th Leipzig Expertworkshop on Equine Reproductive Medicine.
(Leipzig, Germany)
2014/01 Novel luteolytic mechanisms in equine corpora lutea: the role of nodal signaling pathway and its interaction with Tumor necrosis factor alpha, interferon gamma and fas ligand. XI International Symposium on equine Reproduction
(Hamilton, New Zealand)
2013/11/06 A expressão dos receptores da progesterona, do estradiol e da ocitocina em diferentes porções do oviduto equino IIIªs Jornadas do Grupo de Trabalho de Investigação em Equídeos
(Golegã, Portugal)
2013/11/06 Influência das Redes Extracelulares de Neutrófilos (NETs) e de citocinas na função secretora e na fibrose no endométrio de éguas IIIªs Jornadas do Grupo de Trabalho de Investigação em Equídeos
(Golegã, Portugal)
2013/10 Neutrophil extracellular traps and cytokines on the expression of genes involved in mare endometrosis Endometritis as a cause infertility in domestic animals: new diagnostic and therapeutic strategies
(Olsztyn, Poland)
2013/10 Neutrophil extracellular traps and cytokines on the expression of genes involved in mare endometrosis. Endometritis as a cause infertility in domestic animals: new diagnostic and therapeutic strategies
(Olsztyn, Poland)
2013/09 Expression of progesterone, estradiol and oxytocin receptors in different portions of the equine oviduct 17th Conference of European society for Domestic Animal Reproduction.
(Bolonha, Italy)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2022/01 - 2023/01 Hipotiroidismo canino: revisão de literatura e descrição de 4 casos clínicos
Supervisor
 Mestrado Integrado em Medicina Veterinária (Master)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
2023 - 2023 Deteção molecular de Herpesvírus canino no trato genital das cadelas nas diferentes fases do ciclo éstrico
Co-supervisor
 Mestrado Integrado em Medicina Veterinária (Master)
Universidade Lusófona de Humanidades e Tecnologias Faculdade de Medicina Veterinária, Portugal
2023 - 2023 Doenças Associadas ao Diestro e ao Peri-Parto na Cadela: Revisão de Literatura e Descrição de 4 Casos Clínicos
Supervisor
 Mestrado Integrado em Medicina Veterinária (Master)
Universidade Lusófona de Humanidades e Tecnologias Faculdade de Medicina Veterinária, Portugal
2022/01 - 2022/12 Luxação da patela em canídeos
Supervisor
 Mestrado Integrado em Medicina Veterinária (Master)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
2020 - 2020 Relatório de estágio em enfermagem de clínica de animais de companhia, Nanismo Hipofisário
Supervisor of Joana Luís
 Enfermagem Veterinária (Degree)
Instituto Politécnico de Portalegre Escola Superior Agrária de Elvas, Portugal
2020 - 2020 Relatório de estágio em enfermagem de clínica de animais de companhia, Papel do enfermeiro veterinário na triagem e monitorização de urgências veterinárias
Supervisor of Patrícia Teigão
 Enfermagem Veterinária (Degree)
Instituto Politécnico de Portalegre Escola Superior Agrária de Elvas, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2017 - 2018 Participação como monitora de atividades na iniciativa Verão da ULisboa, promovida pela Reitoria da Universidade de Lisboa, na FMV-UL. Participação em ações de divulgação do curso de MIMV junto da comunidade pré-universitária.
Other
 Verão na ULisboa
Universidade de Lisboa, Portugal

Association member

Society Organization name Role
2021/01 - Current Associação Portuguesa de Acupuntura Médico-Veterinária Secretária da Assembleia Geral
2017 - 2017 Associação de Bolseiros do CIISA, dependência da Associação de Estudantes da FMV-UL. Presidente
2016 - 2016 Associação de Bolseiros do CIISA, dependência da Associação de Estudantes da FMV-UL. Vice-Presidente

Committee member

Activity description
Role 		Institution / Organization
2021/09 - 2022/12 Membro avaliador da Comissão de Ética e Bem-Estar Animal da FMV-ULHT– Avaliação de científica e ética de projetos de estágio de alunos do MIMV da ULHT
Member
 Universidade Lusófona de Humanidades e Tecnologias, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2022 - 2023 Animal Physiology I Mestrado Integrado em Medicina Veterinária (Mestrado integrado) Universidade de Évora, Portugal
2022 - 2023 Animal Physiology II Mestrado integrado em Medicina Veterinária (Mestrado integrado) Universidade de Évora, Portugal
2022 - 2023 Anatomy II Mestrado Integrado em Medicina Veterinária (Mestrado integrado) Universidade de Évora, Portugal
2022 - 2023 Anatomy III Mestrado Integrado em Medicina Veterinária (Mestrado integrado) Universidade de Évora, Portugal
2022 - 2023 Exognosis Mestrado Integrado em Medicina Veterinária (Mestrado integrado) Universidade de Évora, Portugal
2022 - 2023 Advanced Studies in Animal Physiology Mestrado em Zootecnia (Mestrado) Universidade de Évora, Portugal
2020 - 2022 Reproduction, Gynecology and Obstetrics II (Coordinator) Medicina Veterinária (Mestrado integrado) Universidade Lusófona de Humanidades e Tecnologias, Portugal
2020 - 2022 Equine Neonatology (Coordinator) Medicina Veterinária (Mestrado integrado) Universidade Lusófona de Humanidades e Tecnologias, Portugal
2020 - 2022 Physiology I (Coordinator) Medicina Veterinária (Mestrado integrado) Universidade Lusófona de Humanidades e Tecnologias, Portugal
2020 - 2022 Physiology II (Coordinator) Medicina Veterinária (Mestrado integrado) Universidade Lusófona de Humanidades e Tecnologias, Portugal
2019 - 2020 Animal Anatomy Enfermagem Veterinária (Licenciatura) Instituto Politécnico de Portalegre Escola Superior Agrária de Elvas, Portugal
2019 - 2020 Animal Physiology Enfermagem Veterinária (Licenciatura) Instituto Politécnico de Portalegre Escola Superior Agrária de Elvas, Portugal
2019 - 2020 Animal Anatomy Cuidados Veterinários (Curso Técnico Superior Profissional) Instituto Politécnico de Portalegre Escola Superior Agrária de Elvas, Portugal
2019 - 2020 Emergency and Hospital Care Enfermagem Veterinária (Licenciatura) Instituto Politécnico de Portalegre Escola Superior Agrária de Elvas, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2022 - Current Veterinary Research Communications Springer
2022 - Current Cells MDPI
2022 - Current Veterinary Medicine MDPI
2021 - Current Scientific Reports Nature
2018 - Current Reproduction in Domestic Animals Willey
Distinctions

Award

2019 1st Prize - Best oral communication
9º Encontro de Formação da Ordem dos Médicos Veterinários, Portugal
2018 2nd Prize - Second best oral communication
8º Encontro de Formação da Ordem dos Médicos Veterinários, Portugal
2011 José Maria Teixeira Prize
Sociedade Portuguesa de Ciências Veterinárias, Portugal
2011 Nunes Petisca Prize
Sociedade Portuguesa de Ciências Veterinárias, Portugal
2005 Teixeira Lopes Prize
Portuguese Rotary Foundation, Portugal