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Sofia Santos Costa is currently an Assistant Researcher at the Unit of Medical Microbiology of IHMT-NOVA and member of “THOP – TB, HIV and opportunistic diseases and pathogens” group of the Global Health and Tropical Medicine (GHTM) R&D center and of the Associated Laboratory “REAL - Associated Laboratory in Translation and Innovation Towards Global Health”. She obtained her PhD in Biomedical Sciences, specialization Microbiology in 2013. She holds a MSc degree in Medical Microbiology and Graduation in Applied Chemistry, specialization Biotechnology. She participates/has participated in several concluded R&D Projects as PI (DREBI - Exploring efflux inhibition to counteract antimicrobial resistance and biofilms in staphylococci, funded by FCT), Co-PI (BIOSAFE - Preventing antimicrobial resistance in the community - the safe use of biocides, funded by FEDER/FCT), or as team member. She is responsible for the Galleria mellonella Research Hub at GHTM/IHMT-NOVA. She is involved in several syllabus of MSc and PhD courses covering topics that overlap with her research areas. She supervises one post-doctoral researcher (co-suoervisor), two PhD students and co-supervises five PhD students. She also supervises two MSc students and co-supervises three MSc students. So far, she has supervised eight MSc students and co-supervised, one PhD student, eighteen MSc students, one BSc student and one Erasmus student. She is a member of the Scientific Council of IHMT-NOVA since July 2020. To date, she has authored/co-authored 43 international peer-reviewed publications (h-index of 18).
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Identification

Personal identification

Full name
Sofia Santos Costa

Citation names

  • Sofia Santos Costa; SS Costa; S Santos Costa

Author identifiers

Ciência ID
E51C-95BC-3797
ORCID iD
0000-0002-4096-2410
Researcher Id
L - 7929 - 2013
Scopus Author Id
7201998885

Email addresses

  • scosta@ihmt.unl.pt (Professional)

Telephones

Telephone
  • 213652600 Ext.: 318 (Professional)

Addresses

  • Instituto de Higiene e Medicina Tropical. Rua da Junqueira, Nº 100, 1349-008 , Lisboa, Lisboa, Portugal (Professional)

Websites

Knowledge fields

  • Natural sciences - Biological Sciences - Microbiology
  • Medical and Health Sciences - Health Sciences - Infectious Diseases
  • Agrarian Sciences - Animal and Dairy Science - Pets

Languages

Language Speaking Reading Writing Listening Peer-review
English Upper intermediate (B2) Advanced (C1) Advanced (C1) Upper intermediate (B2)
French Beginner (A1) Elementary (A2) Beginner (A1) Beginner (A1)
Spanish; Castilian Elementary (A2) Elementary (A2) Beginner (A1) Elementary (A2)
Education
Degree Classification
2017/04/01 - 2017/05/09
Concluded
 Scientific visit to Adriana E. Rosato's Lab (Outros)
Houston Methodist Research Institute, United States
2009 - 2013/11/25
Concluded
 Ciências Biomédicas (Doutoramento)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
"Efflux pump activity in drug resistance of Staphylococcus aureus" (THESIS/DISSERTATION)
 Approved by unanimity
2012/11/25 - 2012/12/17
Concluded
 Scientific visit to the Stefan Schwarz's Workgroup Molecular Microbiology and Antimicrobial Resistance (Outros)
Friedrich-Loeffler-Institut Institut für Nutztiergenetik, Germany
2006 - 2008/07/03
Concluded
 Microbiologia Médica (Mestrado)
Universidade Nova de Lisboa, Portugal
"Phenotypic and genotypic characterization of a Staphylococcus aureus strain adapted to ethidium bromide. " (THESIS/DISSERTATION)
 1st year - 16/20; MSc Thesis-Very Good (max grade)
1999/09/15 - 2005/01/20
Concluded
 Química Aplicada (Licenciatura)
Major in Biotecnologia
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Produção de Proteínas Recombinantes / Production of recombinant proteins" (THESIS/DISSERTATION)
 14/20
2003/07 - 2003/09
Concluded
 SOCRATES Exchange Program (Outros)
National Centre of Scientific Research DEMOKRITOS, Greece
Affiliation

Science

Category
Host institution 		Employer
2023/04/01 - Current Auxiliary Researcher (Research) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2018/12/01 - 2023/03/31 Researcher (Research) Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal

Positions / Appointments

Category
Host institution 		Employer
2020/07/01 - Current Member of the Scientific Council Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2011/04/01 - 2012/12/01 Member of the Pedagogic Council - Students representative of the PhD in Biomedical Sciences Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Others

Category
Host institution 		Employer
2014/09/01 - 2018/11/30 Post-doctoral Fellow (FCT, SFRH/BPD/97508/2013), with the working project "Exploring routes of animal-to-human staphylococci transmission: trying to break the cycle of virulence and antimicrobial Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2014/02/01 - 2014/08/01 Research Fellow (BI) in Project PTDC/BIA-MIC/121859/2010, entitled “Type-II NADH-menaquinone oxidoreductase (NDH-2) and the respiratory chain of M. tuberculosis: new therapeutic targets" Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2013/03/01 - 2013/08/01 Research Fellow (BI) in Project PTDC/BIA-MIC/105509/2008, entitled “Helper compounds against multidrug resistant bacteria: revealing their mechanism of action”, funded by FCT. Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2009/01/01 - 2012/12/31 PhD scholarship (FCT, SFRH/BD/44214/2008), with the working project "Efflux pump activity in drug resistance of Staphylococcus aureus". Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2007/07/01 - 2008/05/31 Research technician - Biotrend SA & IHMT Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Projects

Grant

Designation Funders
2024/01/01 - Current OPUS - Open and Universal Science
101058471
Participant (enrolled researcher for monitorization)
The Oceanic Platform for the Canary Islands (PLOCAN), Spain
 European Union
Ongoing

Contract

Designation Funders
2024/02/01 - Current RESPIRA CV - Airway colonization and microbiome in relation to asthma and atopy in children from Cabo Verde
286790
Researcher
Universidade de Cabo Verde, Cape Verde
 Fundação 'la Caixa'

Fundação Calouste Gulbenkian
Ongoing
2023/06/01 - Current Clarifying the role of efflux and mobilome on antimicrobial resistance and virulence in staphylococci
2022.15300.CBM
Researcher
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
 Fundação para a Ciência e a Tecnologia

Deutscher Akademischer Austauschdienst
Ongoing
2025 - 2027 WOneMoz: Metagenomics surveillance of infectious agents and antimicrobial resistance spread through an integrated One Health and Wastewater-based epidemiological approach in Manhiça, Mozambique
312307
Researcher
Centro de Investigação em Saúde de Manhiça, Mozambique

Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal

University of the Free State Faculty of Health Sciences, South Africa

Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
Fundação Calouste Gulbenkian

Fundação 'la Caixa'
Ongoing
2021/01/01 - 2025/12/31 Translação e Inovação para a Saúde Global (LA-REAL)
LA/P/0117/2020
10.54499/LA/P/0117/2020
Researcher
Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal

Universidade NOVA de Lisboa Comprehensive Health Research Centre, Portugal

Universidade de Lisboa Faculdade de Medicina Dentária, Portugal

Universidade de Coimbra, Portugal

Universidade de Évora, Portugal

Universidade Nova de Lisboa ¿Laboratório de Instrumentação Engenharia Biomédica e Física da Radiação, Portugal

Universidade NOVA de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2020/01/01 - 2024/12/31 Saúde Global e Medicina Tropical
UIDB/04413/2020
Researcher
Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2023/01/01 - 2024/12/30 DREBI - Exploring efflux inhibition to counteract antimicrobial resistance and biofilms in staphylococci
2022.07931.PTDC
10.54499/2022.07931.PTDC
Principal investigator
Universidade NOVA de Lisboa, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2018/10/01 - 2021/09/30 Preventing antimicrobial resistance in the community - the safe use of biocides (BIOSAFE)
PTDC/CAL-EST/30713/2017
Co-Principal Investigator (Co-PI)
Universidade NOVA de Lisboa, Portugal

Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2019/01/01 - 2019/12/31 Saúde Global e Medicina Tropical
UID/Multi/04413/2019
Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal

Universidade NOVA de Lisboa, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2015/01 - 2017/12 Global Health and Tropical Medicine
grant.Provided by PTCRIS: 147267
UID/Multi/04413/2013
Researcher
Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2012/03 - 2015/03 Type-II NADH-menaquinone oxidoreductase (NDH-2) and the respiratory chain of M. tuberculosis: new therapeutic targets to fight tuberculosis
PTDC/BIA-MIC/121859/2010
Research Fellow
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010/03 - 2013/08 Helper compounds against multidrug resistant bacteria: revealing their mechanism of action
PTDC/BIA-MIC/105509/2008
Research Fellow
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2009 - 2013 R&D Centre Centro de Recursos Microbiológicos
PEst-OE/BIA/UI0457/2011
PhD Student Fellow
Universidade Nova de Lisboa, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2024/04/09 - Current EUTOPIA_Health
EUTOPIA_Health
Participant (Researcher selected for a 3-year mentoring and support by VUB University for application for Horizon Europe funding, WP3)
Ongoing
2021/02 - Current WHO Collaborating Center on Health Workforce Policy and Planning.
WHO
Member
Ongoing
2019/11 - Current Network - ENOVAT "European Network for Optimization of Veterinary Antimicrobial Treatment" (COST ACTION)
CA18217
Researcher
Københavns Universitet - Frederiksberg Campus, Denmark
 European Cooperation in Science and Technology
Concluded
2022/05/01 - 2023/07/31 DrugsForNg - Study of the activity of repurposed drugs against Neisseria gonorrhoeae: targeting membrane transport and energy metabolism
UID/Multi/04413/2020
Researcher
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
 Universidade Nova de Lisboa Saúde Global e Medicina Tropical
Concluded
2021/03/01 - 2022/02/28 Companion Animals Veterinary Healthcare: any leading role in the spreading of Carbapenem Resistant Enterobacteriaceae?
CIISA - INOV
Researcher
Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal, Portugal
 Universidade de Lisboa Centro de Investigação Interdisciplinar em Sanidade Animal
Concluded
Outputs

Publications

Conference poster
  1. Garrine, Marcelino; Neves, Joana; Andrade, Mariana; Messa Jr, Augusto; Boisen, Nadia; Couto, Isabel; Costa, Sofia Santos ; Mandomando, Inacio. "Exploring the virulence potential of Escherichia coli of ST131 fimH27 subclone causing infantile bacteraemia in Mozambican children.". Paper presented in ESCMID Global 2025 - Congress of the European Society of Clinical Microbiology and Infectious Diseases, 2025.
  2. Andrade, Mariana; Neves, Joana; Bento, Maria; Marques, Joana; Seabra, Sofia G.; Viveiros, Miguel; Rodrigues, Liliana; et al. "Evaluation of candidate drugs for repurposing in a Galleria mellonella staphylococcal infection model.". Paper presented in ESCMID Global 2025 - Congress of the European Society of Clinical Microbiology and Infectious Diseases, 2025.
  3. Andrade, Mariana; Neves, Joana; Marques, Joana; Armada, Ana; Rodrigues, Liliana; Viveiros, Miguel; Silveira, Henrique; Couto, Isabel; Costa, Sofia Santos . "Galleria mellonella research hub: a new in vivo infection model at GHTM/IHMT-NOVA.". Paper presented in NOVAHealth VII International Conference “Tackling Pandemics: Strategies for Prevention, Preparedness and Response”, 2024.
  4. Ferreira, Carolina; Leal, Marta; Andrade, Mariana; Abrantes, Patrícia; Viveiros, Miguel; Costa, Sofia Santos ; Couto, Isabel. "Occurrence of norA and other multidrug efflux pump determinants across the Staphylococcus genus". Paper presented in NOVAHealth VII International Conference “Tackling Pandemics: Strategies for Prevention, Preparedness and Response”, 2024.
  5. Morais, Catarina; Costa, Sofia Santos ; Leal, Marta; Ramos, Bárbara; Andrade, Mariana; Ferreira, Carolina; Abrantes, Patrícia; Pomba, Constança; Couto, Isabel. "High antimicrobial resistance and genetic diversity of S. pseudintermedius associated with skin and soft-tissue infections in companion animals in Lisbon, Portugal.". Paper presented in NOVAHealth VII International Conference “Tackling Pandemics: Strategies for Prevention, Preparedness and Response”, 2024.
  6. Marques, Débora; Costa, Sofia Santos ; Rodrigues, Liliana. "Identification of efflux inhibitors through a drug repurposing strategy in Candida albicans.". Paper presented in NOVAHealth VII International Conference “Tackling Pandemics: Strategies for Prevention, Preparedness and Response”, 2024.
  7. Vital, Joana; Marques, Andreia; Tanoeiro, Luís; Domingos, C; Sequeira, Alice; Costa, Sofia Santos ; Oleastro, Mónica; Vale, Filipa. "Helicobacter pylori carrying prophages: winners in fitness and virulence?". Paper presented in 37th Workshop of the European Helicobacter and Microbiota Study Group (EHMSG 2024), 2024.
  8. Morais, Catarina; Costa, Sofia Santos; Hanke, Dennis; Krüger-Haker, Henrike; Santos, Ana; Pomba, Constança; Fessler, Andrea T.; Schwarz, Stefan; Couto, Isabel. "Genomic analysis of Staphylococcus pseudintermedius associated with skin and soft tissue infections in companion animals". Paper presented in 19th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI), Perth, Australia, 2024.
  9. Andrade, Mariana; Couto, Isabel; Costa, Sofia Santos . "Efflux-mediated resistance in Staphylococcus coagulans.". Paper presented in 19th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI), Perth, Australia, 2024.
  10. Ferreira, Carolina; Leal, Marta; Andrade, Mariana; Abrantes, Patrícia; Viveiros, Miguel; Costa, Sofia Santos ; Couto, Isabel. "Occurrence of norA and other multidrug efflux pump determinants across the Staphylococcus genus.". Paper presented in 19th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI), Perth, Australia, 2024.
  11. Garrine, Marcelino; Costa, Sofia Santos ; Andrade, Mariana; Neves, Joana; Messa Jr, Augusto; Nhampossa, Tacilta; Mandomando, Inacio; Couto, Isabel. "Phenotypic and molecular characterization of Staphylococcus aureus associated with paediatric bacteraemia in Manhiça District Hospital, Mozambique, over two decades.". Paper presented in 19th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI), Perth, Australia, 2024.
  12. Marques, Margarida; Costa, Sofia Santos; Pinto, Sandra N; Silveira, Henrique. "Characterization of biofilm formation by bacteria associated with the midgut of Anopheles mosquito, vector of malaria". Paper presented in 34th European Congress on Clinical Microbiology and Infectious Diseases (ECCMID), 2024.
  13. Serrano, Isa; Mil-Homens, Dalila; Pires, Ricardo; Bonifácio, Vasco; Guerreiro, Joana F; Cunha, Eva; Costa, Sofia Santos; Tavares, Luís; Oliveira, Manuela. "Potential of an antimicrobial peptide and a polyurea pharmadendrimer for treating mild superficial diabetic foot infections by S. aureus and P. aeruginosa". Paper presented in 34th European Congress on Clinical Microbiology and Infectious Diseases (ECCMID), 2024.
  14. Serrano, Isa; Mil-Homens, Dalila; Guerreiro, Joana F; Cunha, Eva; Costa, Sofia Santos ; Tavares, Luís; Oliveira, Manuela. "Full survival of Galleria mellonella infected with Staphylococcus aureus after treatment with Nisin Z". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec23), Covilhã, Portugal, 2023.
  15. Ferreira, Carolina; Morais, Catarina; Zacharias, Paula; Abrantes, Patrícia; Pomba, Constança; Costa, Sofia Santos ; Couto, Isabel. "Chlorhexidine and benzalkonium chloride activity against Staphylococcus aureus and Staphylococcus pseudintermedius from skin and soft-tissue infections in companion animals". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec23), Covilhã, Portugal, 2023.
  16. Morais, Catarina; Costa, Sofia Santos ; Hanke, Dennis; Krüger-Haker, Henrietta ; Santos, Ana; Pomba, Constança; Fessler, Andrea T.; Schwarz, Stefan; Couto, Isabel. "Plasmid profiling of Staphylococcus pseudintermedius associated with skin and soft tissue infections in companion animals". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec23), Covilhã, Portugal, 2023.
  17. Garrine, Marcelino; Andrade, Mariana; Mandomando, Inacio; Couto, Isabel. "Exploring the virulence potential of CC152 and CC121 S. aureus strains related to paediatric community-acquired bactraemia in the Manhiça district hospital, Mozambique". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec23), Covilhã, Portugal, 2023.
  18. Neves, Joana; Antunes, Carolina; Andrade, Mariana; Bento, Maria; Couto, Isabel; Rodrigues, Liliana; Costa, Sofia Santos . "Drug repurposing for identification of new efflux inhibitors and/or antibiofilm agents against Staphylococcus aureus and Staphylococcus epidermidis". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec23), Covilhã, Portugal, 2023.
  19. Rodrigues, Telma; Andrade, Mariana; Marques, Joana; Rodrigues, Liliana; Viveiros, Miguel; Silveira, Henrique; Couto, Isabel; Costa, Sofia Santos. "Implementation of a Galleria mellonella infection model at GHTM/IHMT-NOVA". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec23), Covilhã, Portugal, 2023.
  20. Marques, Margarida; Costa, Sofia Santos ; Pinto, Sandra N; Silveira, Henrique. "Characterization of biofilm formation by bacteria associated with the midgut of Anopheles mosquito, vector of malaria". Paper presented in 3rd iBB Workshop, Instituto Superior Técnico, Universidade de Lisboa, Portugal, 2023.
  21. Morais, Catarina; Costa, Sofia Santos; Leal, Marta; Ramos, Bárbara; Andrade, Mariana; Ferreira, Carolina; Abrantes, Patrícia; Pomba, Constança; Couto, Isabel. "High antimicrobial resistance and genetic diversity in S. pseudintermedius associated with skin and soft-tissue infections in companion animals in Lisbon, Portugal". Paper presented in 6th National Congress of Tropical Medicine (CNTM), Lisbon, Portugal, 2023.
  22. Leal, Marta; Morais, Catarina; Ramos, Bárbara; Abrantes, Patrícia; Pomba, Constança; Costa, Sofia Santos ; Couto, Isabel. "Efflux as a resistance mechanism in the veterinary pathogen Staphylococcus pseudintermedius". Paper presented in 6th National Congress of Tropical Medicine (CNTM), Lisbon, Portugal, 2023.
  23. Neves, Joana; Antunes, Carolina; Andrade, Mariana; Couto, Isabel; Rodrigues, Liliana; Costa, Sofia Santos . "Drug repurposing for identification of new efflux inhibitors and/or antibiofilm agents against Staphylococcus aureus and Staphylococcus epidermidis". Paper presented in 6th National Congress of Tropical Medicine (CNTM), Lisbon, Portugal, 2023.
  24. Mendes, Ana; Costa, Sofia Santos; Rodrigues, Liliana. "Evaluation of the activity of repurposed drugs that target energy metabolism in Escherichia coli". Paper presented in 33rd European Congress on Clinical Microbiology and Infectious Diseases (ECCMID), Online/Copenhagen, Denmark, 2023.
  25. Garrine, Marcelino; Quintó, Llorenç; Costa, Sofia Santos ; Messa Jr., Augusto; Massinga, Arsénia J.; Vubil, Delfino; Nhampossa, Tacilta; et al. "Epidemiology and clonality of Staphylococcus aureus bacteraemia in children < 5 years of age admitted to the Manhiça District Hospital, Mozambique, 2001–2019". Paper presented in 33rd European Congress on Clinical Microbiology and Infectious Diseases (ECCMID), Online/Copenhagen, Denmark, 2023.
  26. Morais, Catarina; Ferreira, Carolina; Zacharias, Paula; Abrantes, Patrícia; Pomba, Constança; Costa, Sofia Santos ; Couto, Isabel. "Assessment of chlorhexidine activity against Staphylococcus aureus and Staphylococcus pseudintermedius from skin and soft-tissue infections in companion animals". Paper presented in 33rd European Congress on Clinical Microbiology and Infectious Diseases (ECCMID), Online/Copenhagen, Denmark, 2023.
  27. Neves, Joana; Antunes, Carolina; Andrade, Mariana; Couto, Isabel; Rodrigues, Liliana; Costa, Sofia Santos. "Drug repurposing for identification of new efflux inhibitors and/or antibiofilm agents against Staphylococcus aureus and Staphylococcus pseudintermedius". Paper presented in 33rd European Congress on Clinical Microbiology and Infectious Diseases (ECCMID), Online/Copenhagen, Denmark, 2023.
  28. Ferreira, Carolina; Abrantes, Patrícia; Costa, Sofia Santos; Viveiros, Miguel; Couto, Isabel. "Occurrence and variability of norA and other main multidrug efflux pump determinants across the Staphylococcus genus". Paper presented in 33rd European Congress on Clinical Microbiology and Infectious Diseases (ECCMID), Online/Copenhagen, Denmark, 2023.
  29. Morais, Catarina; Costa, Sofia Santos; Pomba, Constança; Couto, Isabel. "Assessment of chlorohexidine and benzalkonium chloride activity against Staphylococcus pseudintermedius from skin and soft-tissue infections in companion animals.". Paper presented in XIII IHMT Scientific Day, 2022.
  30. Silva, Joana; Menezes, Juliana; Amaral, Andreia J; Costa, Sofia Santos ; Pomba, Constança. "KPC-3-, OXA-181- producing Klebsiella pneumoniae clonal group 147 and OXA-48-producing Escherichia coli detected on clinical isolates from companion animals". Paper presented in XIII IHMT Scientific Day, 2022.
  31. Ferreira, Carolina; Abrantes, Patrícia; Costa, Sofia Santos; Couto, Isabel. "Occurrence and variability of the efflux pump gene norA in staphylococci". Paper presented in XIII IHMT Scientific Day, 2022.
  32. Garrine, Marcelino; Costa, Sofia Santos; Mandomando, Inacio; Couto, Isabel. "Epidemiology and clinical presentation of Staphylococcus aureus bacteraemia in children <5 years of age admitted to the Manhiça district hospital, Mozambique, 2001-2019". Paper presented in XIII IHMT Scientific Day, 2022.
  33. Ferreira, Carolina; Costa, Sofia Santos; Abrantes, Patrícia; Viveiros, Miguel; Couto, Isabel. "Rapid screening of norA alleles among Staphylococcus aureus strains causing SSTIs in different hosts". Paper presented in 32nd European Congress on Clinical Microbiology and Infectious Diseases (ECCMID), Lisbon/webconference, 2022.
  34. Andrade, Mariana; Oliveira, Ketlyn; Morais, Catarina; Abrantes, Patrícia; Pomba, Constança; Rosato, Adriana E.; Couto, Isabel; Costa, Sofia Santos. "Increased virulence potential of biofilm-producing coagulase-positive staphylococci associated with animal pyoderma". Paper presented in 32nd European Congress on Clinical Microbiology and Infectious Diseases (ECCMID), Lisbon/webconference, 2022.
  35. Leal, Marta; Costa, Sofia Santos; Ramos, Bárbara; Morais, Catarina; Ferreira, Carolina; Pomba, Constança; Couto, Isabel. "Efflux and biocide reduced susceptibility in Staphylococcus pseudintermedius". Paper presented in 32nd European Congress on Clinical Microbiology and Infectious Diseases (ECCMID), Lisbon/webconference, 2022.
  36. Andrade, Mariana; Oliveira, Ketlyn; Morais, Catarina; Abrantes, Patrícia; Pomba, Constança; Rosato, Adriana E.; Couto, Isabel; Costa, Sofia Santos. "Increased virulence potential of biofilm-producing coagulase-positive staphylococci associated with animal pyoderma". Paper presented in 5th Annual Texas Medical Center Antimicrobial Resistance & Stewardship Conference, webconference, 2022.
  37. Morais, Catarina; Costa, Sofia Santos; Pomba, Constança; Couto, Isabel. "Molecular characterization of Staphylococcus pseudintermedius associated with skin and soft tissue infections in pets, Portugal.". Paper presented in XII IHMT Scientific Day, 2021.
  38. Silva, Joana; Amaral, Andreia; Costa, Sofia Santos; Pomba, Constança. "Screening of Enterobacterales clinical strains from companion animals reveals carbapenemase-producing isolates". Paper presented in XII IHMT Scientific Day, 2021.
  39. Ramos, Bárbara; Costa, Sofia Santos; Leal, Marta; Morais, Catarina; Pomba, Constança; Couto, Isabel. "Fluoroquinolone resistance and associated mechanisms in Staphylococcus pseudintermedius". Paper presented in Congresso Nacional de Microbiologia e Biotecnologia 2021 (MicroBiotec21), webconference, 2021.
  40. Leal, Marta; Costa, Sofia Santos; Ramos, Bárbara; Ferreira, Carolina; Pomba, Constança; Couto, Isabel. "Evaluation of efflux activity in Staphylococcus pseudintermedius and its contribution for biocide decreased susceptibility". Paper presented in Congresso Nacional de Microbiologia e Biotecnologia 2021 (MicroBiotec21), webconference, 2021.
  41. Garrine, Marcelino; Costa, Sofia Santos; Mandomando, Inacio; Couto, Isabel. "Antimicrobial resistance and molecular typing of Staphylococcus aureus causing bacteraemia in children aged less than 5 years in Southern Mozambique, 2001-2019". Paper presented in Congresso Nacional de Microbiologia e Biotecnologia 2021 (MicroBiotec21), webconference, 2021.
  42. Morais, Catarina; Costa, Sofia Santos; Andrade, Mariana; Ramos, Bárbara; Leal, Marta; Abrantes, Patrícia; Pomba, Constança; Couto, Isabel. "Molecular characterization of Staphylococcus pseudintermedius associated with skin and soft tissue infections in pets, Portugal". Paper presented in Congresso Nacional de Microbiologia e Biotecnologia 2021 (MicroBiotec21), webconference, 2021.
  43. Oliveira, Ketlyn; Abrantes, Patrícia; Ferreira, Carolina; Ribeiro, Rute; Serrano, Maria; Pomba, Constança; Couto, Isabel; Costa, Sofia Santos. "Virulence traits of Staphylococcus aureus associated with skin and soft tissue infections in humans and animals". Paper presented in Congresso Nacional de Microbiologia e Biotecnologia 2021 (MicroBiotec21), webconference, 2021.
  44. Andrade, Mariana; Morais, Catarina; Abrantes, Patrícia; Pomba, Constança; Couto, Isabel; Costa, Sofia Santos. "Biofilm production by Staphylococcus pseudintermedius associated with animal pyoderma". Paper presented in Congresso Nacional de Microbiologia e Biotecnologia 2021 (MicroBiotec21), webconference, 2021.
  45. Costa, Sofia Santos; Ferreira, Carolina; Morais, Catarina; Abrantes, Patrícia; Pomba, Constança; Couto, Isabel. "Emergence of staphylococcal non-wild-type populations to biocides in a One Health perspective: are there reasons for concern?". Paper presented in Congresso Nacional de Microbiologia e Biotecnologia 2021 (MicroBiotec21), webconference, 2021.
  46. Silva, Joana; Menezes, Juliana; Amaral, Andreia; Costa, Sofia Santos; Pomba, Constança. "A hygiene and monitorization program for small animal veterinary practices: A Pilot-study". Paper presented in Congresso Nacional de Microbiologia e Biotecnologia 2021 (MicroBiotec21), webconference, 2021.
  47. Morais, Catarina; Costa, Sofia Santos; Andrade, Mariana; Ramos, Bárbara; Leal, Marta; Abrantes, Patrícia; Pomba, Maria Constança; Couto, Isabel. "Clonal lineages of Staphylococcus pseudintermedius associated with skin and soft tissue infections in pets, Portugal". Paper presented in 31st European Congress on Clinical Microbiology and Infectious Diseases (ECCMID), webconference, 2021.
  48. Morais, Catarina; Costa, Sofia Santos; Abrantes, Patrícia; Pomba, Constança; Couto, Isabel. "Antibiotic resistance in Staphylococcus pseudintermedius associated with skin and soft tissue infections in dogs and cats". Paper presented in 30th European Congress on Clinical Microbiology and Infectious Diseases (ECCMID), 2020.
  49. Costa, Sofia Santos; Ribeiro, Rute; Oliveira, Valéria; Serrano, Maria; Ferreira, Carolina; Morais, Catarina; Pomba, Constança; Couto, Isabel. "Antibiotic and biocide resistance among staphylococci causing SSTIs in companion animals in Portugal". Paper presented in 30th European Congress on Clinical Microbiology and Infectious Diseases (ECCMID)., 2020.
  50. Oliveira, Valéria; Costa, Sofia Santos; Pomba, Constança; Couto, Isabel. "Susceptibility to antibiotic and biocides in Staphylococcus schleiferi associated with canine SSTIs". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec19). Coimbra, Portugal, 2019.
  51. Ribeiro, Rute; Costa, Sofia Santos; Pomba, Constança; Couto, Isabel. "Biocide and antibiotic resistance in Staphylococcus aureus causing skin and soft tissue infections in companion animals". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec19). Coimbra, Portugal, 2019.
  52. Ferreira, Carolina; Costa, Sofia Santos; Pomba, Constança; Couto, Isabel. "Resistance to biocides and antibiotics in Staphylococcus aureus associated with SSTIs in ambulatory patients". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec19). Coimbra, Portugal, 2019.
  53. Costa, Sofia Santos ; Abrantes, Patrícia; Morais, Catarina; Viveiros, Miguel; Rosato, Adriana E.; Couto, Isabel. "Exploring the staphylococcal efflux-mediated response to ethidium bromide, an efflux pump substrate". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec19). Coimbra, Portugal, 2019.
  54. Malheiro, Joana; Costa, Sofia Santos; Borges, Fernanda; Couto, Isabel; Maillard, Jean-Yves; Simões, Manuel. "Cinnamaldehyde modulates efflux of antimicrobial resistant Staphylococcus aureus". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec19). Coimbra, Portugal, 2019.
  55. Serrano, Maria; Costa, Sofia Santos; Pomba, Constança; Couto, Isabel. "Staphylococcal clonal lineages associated with skin and soft tissue infections in humans and pets". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec19). Coimbra, Portugal, 2019.
  56. Morais, Catarina; Costa, Sofia Santos; Pomba, Constança; Couto, Isabel. "Antibiotic resistance in Staphylococcus pseudintermedius causing skin and soft-tissue infections in companion animals". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec19). Coimbra, Portugal, 2019.
  57. Morais, Catarina; Costa, Sofia Santos; Pomba, Constança; Couto, Isabel. "Antibiotic resistance in Staphylococcus pseudintermedius causing skin and soft-tissue infections in pets". Paper presented in 1st International Conference of the European College of Veterinary Microbiology. Athens, Greece, 2019.
  58. Malheiro, Joana; Costa, Sofia Santos; Couto, Isabel; Borges, Fernanda; Maillard, Jean-Yves; Simões, Manuel. "Phytochemical derivatives as Staphylococcus aureus efflux pump modulators". Paper presented in 3rd International Caparica Conference in Antibiotic Resistance (IC2AR). Caparica, Portugal, 2019.
  59. Costa, Sofia Santos; Abrantes, Patrícia; Morais, Catarina; Viveiros, Miguel; Rosato, Adriana E.; Couto, Isabel. "Exploring the staphylococcal efflux-mediated response to ethidium bromide, an efflux pump substrate". Paper presented in Gordon Conference "Multi-Drug Efflux Systems" 2019. Lucca, Italy, 2019.
  60. Morais, Catarina; Costa, Sofia Santos; Pomba, Constança; Couto, Isabel. "Antibiotic resistance in Staphylococcus pseudintermedius causing skin and soft tissue infections in pets". Paper presented in IV NOVA Genetic Workshop. Lisbon, Portugal, 2019.
  61. Morais, Catarina; Costa, Sofia Santos; Pomba, Constança; Couto, Isabel. "Antimicrobial resistance in staphylococci causing skin and soft tissue infections". Paper presented in 9th Scientific Day of IHMT-NOVA. Lisbon, Portugal, 2018.
  62. Garrine, Marcelino; Costa, Sofia Santos; Mandomando, Inacio; Couto, Isabel. "Molecular characterization of Staphylococcus aureus isolates from bactereamia in children from Manhiça District, Mozambique, 2011-2016". Paper presented in 9th Scientific Day of IHMT-NOVA. Lisbon, Portugal, 2018.
  63. Costa, Sofia Santos ; Kadlec, Kristina; Viveiros, Miguel; Melo-Cristino, José; Schwarz, Stefan; Couto, Isabel. "Complete sequences of two plasmids carrying genes for resistance to antibiotics, heavy-metals, biocides and/or virulence". Paper presented in 18th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI), Copenhagen, Denmark, 2018.
  64. Costa, Sofia Santos ; Santos, Cláudia Mineiro; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Frequent biofilm production by Staphylococcus epidermidis causing infections in pets or colonizing veterinary staff". Paper presented in 18th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI), Copenhagen, Denmark, 2018.
  65. Costa, Sofia Santos ; Rosa, Mafalda; Holtreman, Frederico; Rodrigues, Ana Catarina; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Emergence of non-wild-type populations towards biocides in Staphylococcus epidermidis colonizing veterinary staff". Paper presented in 18th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI), Copenhagen, Denmark, 2018.
  66. Costa, Sofia Santos ; Rosa, Mafalda; Belas, Adriana; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Biocide susceptibility in Staphylococcus epidermidis causing infections in pets". Paper presented in 18th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI), Copenhagen, Denmark, 2018.
  67. Costa, Sofia Santos ; Rosato, Adriana E.; Viveiros, Miguel; Couto, Isabel. "Development of multidrug resistance in staphylococci driven by efflux". Paper presented in 18th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI), Copenhagen, Denmark, 2018.
  68. Costa, Sofia Santos; Lopes, Elizeth; Pieroni, Marco; Machado, Diana; Costantino, Gabriele; Viveiros, Miguel; Couto, Isabel. "Mycobacterium smegmatis model for the rapid screening of new compounds with efflux inhibitory activity and antimycobacterial activity". Paper presented in 1st Symposium of Tuberculosis and Non-tuberculous mycobacteria. Coimbra, Portugal, 2018.
  69. Francisco, Moisés; Costa, Sofia Santos; Belas, Adriana; Ramos, Jorge; Couto, Isabel; Pomba, Constança; Viveiros, Miguel. "Antimicrobial resistance and molecular characterization of Salmonella enterica serotype Typhi isolated in Luanda, Angola, in human specimens during 2013-2014". Paper presented in VIII Scientific Day of IHMT-NOVA. Lisbon, Portugal, 2017.
  70. Costa, Sofia Santos; Rosa, Mafalda; Rodrigues, Ana Catarina; Santos, Cláudia Mineiro; Holtreman, Frederico; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Characterization of antimicrobial resistance in Staphylococcus epidermidis colonizing veterinary staff and students". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec17). Porto, Portugal, 2017.
  71. Santos, Cláudia Mineiro; Costa, Sofia Santos; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Prevalence of biofilm production in Staphylococcus epidermidis colonizing veterinary staff and students". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec17). Porto, Portugal, 2017.
  72. Holtreman, Frederico; Costa, Sofia Santos; Rosa, Mafalda; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Characterization of plasmid encoded efflux determinants from Staphylococcus epidermidis". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec17). Porto, Portugal, 2017.
  73. Francisco, Moisés; Costa, Sofia Santos; Belas, Adriana; Ramos, Jorge; Couto, Isabel; Pomba, Constança; Viveiros, Miguel. "Antimicrobial resistance and molecular characterization of Salmonella enterica serotype Typhi isolated in Luanda, Angola, in human specimens during 2013-2014". Paper presented in Encontro Ciência 2017. Lisbon, Portugal, 2017.
  74. Couto, Isabel; Costa, Sofia Santos; Viveiros, Miguel; Pomba, Constança. "NorA mediated efflux in Staphylococcus epidermidis". Paper presented in 4th National Congress of Tropical Medicine (CNMT). Lisbon, Portugal, 2017.
  75. Mattos, Karen; Costa, Sofia Santos; Couto, Isabel; Levy, Carlos Emílio; Marques, Cátia; Moriel, Patrícia; Pomba, Constança; Viveiros, Miguel. "Molecular epidemiology and genotypic characterization of Klebsiella pneumoniae MDR strains from a University Hospital, Brazil". Paper presented in 4th National Congress of Tropical Medicine (CNMT). Lisbon, Portugal, 2017.
  76. Santos, Cláudia Mineiro; Costa, Sofia Santos; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Correlation of biofilm production with efflux activity and antimicrobial resistance in Staphylococcus epidermidis". Paper presented in 4th National Congress of Tropical Medicine (CNMT). Lisbon, Portugal, 2017.
  77. Rosa, Mafalda; Costa, Sofia Santos; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Contribution of efflux to antimicrobial resistance in Staphylococcus epidermidis". Paper presented in 4th National Congress of Tropical Medicine (CNMT). Lisbon, Portugal, 2017.
  78. Holtreman, Frederico; Costa, Sofia Santos; Rosa, Mafalda; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Influence of efflux in antibiotic resistance and biocide reduced susceptibility in Staphylococcus epidermidis". Paper presented in 4th National Congress of Tropical Medicine (CNMT). Lisbon, Portugal, 2017.
  79. Costa, Sofia Santos ; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "The role of efflux systems on antimicrobial resistance development in Staphylococcus epidermidis". Paper presented in Gordon Conference "Multi-Drug Efflux Systems". Galveston, USA, 2017.
  80. Felicetti, Tommaso; Cannalire, Rolando; Manfroni, Giuseppe; Tabarrini, Oriana; Machado, Diana; Couto, Isabel; Costa, Sofia Santos; Viveiros, Miguel; Sabatini, Stefano. "Natural isoflavone biochanin-A as a template for the design of new and potent 3-phenylquinolone inhibitors of the nontuberculous mycobacteria efflux pumps". Paper presented in XXIV National Meeting in Medicinal Chemistry and 10th Young Medicinal Chemist's Symposium. Perugia, Italy, 2016.
  81. Costa, Sofia Santos ; Belas, Adriana; Couto, Natacha; Rodrigues, Ana Catarina; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Biocide susceptibility profiles of staphylococci colonizing humans in close contact with pets". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec15). Évora, Portugal, 2015.
  82. Azzali, Elisa; Pieroni, Marco; Machado, Diana; Costa, Sofia Santos; Couto, Isabel; Viveiros, Miguel; Costantino, Gabriele. "Rational design and synthesis of thioridazine analogues as enhancers of the antituberculosis therapy". Paper presented in Spanish-Italian Medicinal Chemistry Congress (SIMCC2015). Barcelona, Spain, 2015.
  83. Cabral, Vanessa; Luo, Xuan; Junqueira, Elisabete; Mulhovo, S; Costa, Sofia Santos; Duarte, Aida; Couto, Isabel; Viveiros, Miguel; Ferreira, Maria José Umbelino. "Zanthoxylum capense constituents and derivatives: Effects on the activity of antibiotics against Staphylococcus aureus strains". Paper presented in 62nd International Congress and Annual Meeting of the Society of Medicinal Plant and Natural Product Research. Guimarães, Portugal, 2014.
    10.1055/s-0034-1395089
  84. Costa, Sofia Santos ; Viveiros, Miguel; Melo-Cristino, José; Couto, Isabel. "The role of efflux in the development of multidrug resistance phenotypes in Staphylococcus aureus". Paper presented in 16th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI). Chicago, USA, 2014.
  85. Costa, Sofia Santos ; Viveiros, Miguel; Melo-Cristino, José; Couto, Isabel. "Impact of active efflux in the development of MDR phenotypes in Staphylococcus aureus". Paper presented in 24th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). Barcelona, Spain, 2014.
  86. Branquinho, Rita; Moço, Salomé; Costa, Sofia Santos; Couto, Isabel; Viveiros, Miguel; Martins, Rodrigo; Fortunato, Elvira. "Low cost paper-based materials functionalized with nanoparticles for antibacterial applications". Paper presented in Nanoscience and Nanotechnology International Conference. Oporto. Portugal, 2014.
  87. Costa, Sofia Santos ; Viveiros, Miguel; Melo-Cristino, José; Couto, Isabel. "Characterization of a multiresistance plasmid from a methicillin-resistant Staphylococcus aureus clinical strain". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec13). Aveiro, Portugal, 2013.
  88. Palma, Cláudia; Costa, Sofia Santos; Viveiros, Miguel; Melo-Cristino, José; Couto, Isabel. "The role of plasmid determinants in the resistance of Staphylococcus aureus to antimicrobial agents". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec13). Aveiro, Portugal, 2013.
  89. Costa, Sofia Santos ; Viveiros, Miguel; Melo-Cristino, José; Couto, Isabel. "Efflux as a first-line response to fluoroquinolones and other antimicrobials in Staphylococcus aureus". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec13). Aveiro, Portugal, 2013.
  90. Costa, Sofia Santos ; Viveiros, Miguel; Couto, Isabel. "Relevância clínica de sistemas de efluxo na resistência a compostos antimicrobianos em Staphylococcus aureus". Paper presented in III Scientific Day of IHMT-NOVA. Lisbon, Portugal, 2012.
  91. Mourato, Cláudia; Costa, Sofia Santos; Viveiros, Miguel; Amaral, Leonard; Melo-Cristino, José; Couto, Isabel. "Co-resistance to biocides and beta-lactams in a MRSA clinical isolate". Paper presented in 15th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI). Lyon, France, 2012.
  92. Couto, Natacha; Belas, Adriana; Costa, Sofia Santos; Couto, Isabel; Pomba, Constança. "Comparative analysis of antimicrobial biocide susceptibility data of methicillin-resistant and -susceptible S. pseudintermedius". Paper presented in 15th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI). Lyon, France, 2012.
  93. Costa, Sofia Santos ; Viveiros, Miguel; Amaral, Leonard; Butaye, Patrick; Couto, Isabel. "Susceptibility profiles of antibiotics, biocides and dyes in Staphylococcus aureus from pigs: correlation with efflux activity". Paper presented in 15th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI). Lyon, France, 2012.
  94. Costa, Sofia Santos; Viveiros, Miguel; Amaral, Leonard; Melo-Cristino, José; Couto, Isabel. "Efflux-mediated resistance to quaternary ammonium compounds in methicillin resistant Staphylococcus aureus (MRSA) clinical isolates". Paper presented in 15th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI). Lyon, France, 2012.
  95. Couto, Natacha; Belas, Adriana; Fessler, Andrea T.; Costa, Sofia Santos; Tilley, Paula; Couto, Isabel; Kadlec, Kristina; Schwarz, Stefan; Pomba, Constança. "Loss of the mecA gene during storage of a methicillin-resistant Staphylococcus cohnii subsp. cohnii strain". Paper presented in 15th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI). Lyon, France, 2012.
  96. Couto, Natacha; Belas, Adriana; Fessler, Andrea T.; Costa, Sofia Santos ; Tilley, Paula; Couto, Isabel; Kadlec, Kristina; Schwarz, Stefan; Pomba, Constança. "Minimum bactericidal concentrations of four biocides and the presence of qac genes". Paper presented in 15th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI). Lyon, France, 2012.
  97. Couto, Natacha; Belas, Adriana; Fessler, Andrea T.; Costa, Sofia Santos; Tilley, Paula; Couto, Isabel; Kadlec, Kristina; Schwarz, Stefan; Pomba, Constança. "Antimicrobial resistance among equine methicillin-resistant staphylococci". Paper presented in 15th International Symposium of Staphylococci and Staphylococcal Infections (ISSSI). Lyon, France, 2012.
  98. Costa, Sofia Santos; Viveiros, Miguel; Amaral, Leonard; Couto, Isabel. "The role of NorA in the adaptative response of Staphylococcus aureus to stress stimuli". Paper presented in 22nd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). London, UK, 2012.
  99. Costa, Sofia Santos; Mourato, Cláudia; Viveiros, Miguel; Melo-Cristino, José; Amaral, Leonard; Couto, Isabel. "Resistance to biocides conveyed by efflux pumps in clinical isolates of MRSA". Paper presented in 22nd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), London, UK, 2012.
  100. Spengler, Gabriella; Rodrigues, Liliana; Martins, Marta; McCusker, Matthew; Costa, Sofia Santos; Ntokou, Eleni; Szabo, Agnes Mira; et al. "Stress response and resistance of Salmonella enterica serotype Enteritidis to the efflux pump inhibitor neuropleptic drug thioridazine". Paper presented in 22nd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). London, UK, 2012.
  101. Pinto, Antónia; Machado, Diana; Costa, Sofia Santos ; Couto, Isabel; Amaral, Leonard; Viveiros, Miguel. "Multidrug resistance mediated by active efflux in Escherichia coli: new therapeutic strategies using antibiotics and inhibitors of active efflux". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec11). Braga, Portugal, 2011.
  102. Mourato, Cláudia; Costa, Sofia Santos; Viveiros, Miguel; Falcão, Celeste; Melo-Cristino, José; Amaral, Leonard; Couto, Isabel. "Multidrug resistance in a methicillin-resistant Staphylococcus aureus (MRSA) clinical isolate mediated by efflux pump QacA". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec11). Braga, Portugal, 2011.
  103. Costa, Sofia Santos; Viveiros, Miguel; Amaral, Leonard; Couto, Isabel. "The role of NorA in the adaptative response of Staphylococcus aureus to stress stimuli". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec11). Braga, Portugal, 2011.
  104. Costa, Sofia Santos; Mourato, Cláudia; Viveiros, Miguel; Melo-Cristino, José; Couto, Isabel. "Description of a novel staphylococcal pC194-family plasmid carrying the smr efflux pump gene". Paper presented in National Congress of Microbiology and Biotechnology (MicroBiotec11). Braga, Portugal, 2011.
  105. Costa, Sofia Santos; Mourato, Cláudia; Viveiros, Miguel; Melo-Cristino, José; Amaral, Leonard; Couto, Isabel. "Description of a novel pC194-family plasmid carrying the smr efflux pump gene". Paper presented in 51st Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC). Chicago, USA, 2011.
  106. Saraiva, Raul; Costa, Sofia Santos; Couto, Isabel; Viveiros, Miguel; Feio, Maria José; Gameiro, Paula. "The role of enrofloxacin-based-metallocomplexes in the war against bacterial resistance". Paper presented in International Conference on Antimicrobial Resistance (ICAR2010), Valladolid, Spain, 2010.
  107. Costa, Sofia Santos; Viveiros, Miguel; Falcão, Celeste; Melo-Cristino, José; Amaral, Leonard; Couto, Isabel. "Genetic diversity of the Staphylococcus aureus efflux pump gene norA". Paper presented in 462nd WE Heraeus Seminar Transport across membranes: multiple drug resistance, mechanisms and new tools, Jacobs University Bremen, Bremen, Germany, 2010.
  108. Costa, Sofia Santos; Falcão, Celeste; Viveiros, Miguel; Machado, Diana; Martins, Marta; Melo-Cristino, José; Amaral, Leonard; Couto, Isabel. "Importance of efflux systems on the resistance to fluoroquinolones by Staphylococcus aureus". Paper presented in 462nd WE Heraeus Seminar Transport across membranes: multiple drug resistance, mechanisms and new tools. Jacobs University Bremen, Bremen, Germany, 2010.
  109. Costa, Sofia Santos; Falcão, Celeste; Viveiros, Miguel; Melo-Cristino, José; Amaral, Leonard; Couto, Isabel. "Importance of efflux systems on the resistance to fluoroquinolones in Staphylococcus aureus". Paper presented in 20th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). Vienna, Austria, 2010.
  110. Martins, Marta; Viveiros, Miguel; Couto, Isabel; Costa, Sofia Santos; Pacheco, Teresa; Leonard, Amaral. "New method for the rapid screening of efflux pump activity in multi-drug resistant clinical strains". Paper presented in National Congress of Microbiology (Micro09). Vilamoura, Portugal, 2009.
  111. Falcão, Celeste; Costa, Sofia Santos; Viveiros, Miguel; Machado, Diana; Martins, Marta; Melo-Cristino, Jose; Amaral, Leonard; Couto, Isabel. "Importance of efflux systems on the resistance to fluoroquinolones by Staphylococcus aureus". Paper presented in National Congress of Microbiology (Micro09). Vilamoura, Portugal, 2009.
  112. Costa, Sofia Santos; Viveiros, Miguel; Falcão, Celeste; Melo-Cristino, José; Amaral, Leonard; Couto, Isabel. "Genetic diversity of the Staphylococcus aureus efflux pump gene norA". Paper presented in National Congress of Microbiology (Micro09). Vilamoura, Portugal, 2009.
  113. Couto, Isabel; Costa, Sofia Santos; Viveiros, Miguel; Martins, Marta; Amaral, Leonard. "Efflux-mediated response of Staphylococcus aureus exposed to ethidium bromide". Paper presented in 18th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). Barcelona, Spain, 2008.
  114. Costa, Sofia Santos; Couto, Isabel; Viveiros, Miguel; Martins, Marta; Leandro, Clara; Amaral, Leonard. "Characterization of reduced susceptibility to biocides, dyes, and quinolones in a Staphylococcus aureus strain exposed to ethidium bromide". Paper presented in National Congress of Microbiology (Micro07). Lisbon, Portugal, 2007.
Journal article
  1. Patil, Mrunal; Munteanu, Tatiana; Brasseur, Gaël; Ferreira, Carolina; Costa, Sofia Santos ; Couto, Isabel; Athar, Mohd; et al. "Unlocking the Gates: A Novel Diagnostic Molecule for Quantifying Efflux Levels in Gram-Positive Bacteria". Advanced Healthcare Materials (2025): e2404145. https://doi.org/10.1002/adhm.202404145.
    Open access • Published • 10.1002/adhm.202404145
  2. Andrade, Mariana; Neves, Joana; Bento, Maria; Marques, Joana; Seabra, Sofia G.; Silveira, Henrique; Rodrigues, Liliana; et al. Corresponding author: Costa, Sofia Santos . "Evaluation of amlodipine and imipramine efficacy to treat Galleria mellonella infection by biofilm-producing and antimicrobial-resistant Staphylococcus aureus". Antibiotics 14 (2025): 183. https://doi.org/10.3390/antibiotics14020183.
    Open access • Published • 10.3390/antibiotics14020183
  3. Marques, Margarida; Pobre, Vânia; Costa, Sofia Santos ; Pinto, Sandra N; Silveira, Henrique. "Pseudomonas mendocina isolated from Anopheles midguts has greater potential to build thick biofilms than Serratia marcescens.". Submitted to ACS Omega (2025):
    Open access • Under revision
  4. Pereira, Inês A.; André Pina; Beatriz Santos; Inês Vítor; Ana Henriques; João Fernandes; Filomena Pereira; et al. Corresponding author: Rodrigues, Liliana. "Targeting membrane transport and energy metabolism for the identification of new drugs for Neisseria gonorrhoeae using an in silico repurposing strategy". In the last stages of preparation to be submitted to Antibiotics (2025):
  5. Neves, Joana; Andrade, Mariana; Antunes, Carolina; Nunes, Matilde; Bento, Maria; Viveiros, Miguel; Rodrigues, Liliana; Couto, Isabel; Costa, Sofia Santos . Corresponding author: Costa, Sofia Santos . "Screening new drugs targeting efflux and biofilms in Staphylococcus aureus and Staphylococcus epidermidis identified by an in silico drug repurposing approach.". In final stages of preparation to be submitted to Scientific Reports (2025):
  6. Marques, Débora; Costa, Sofia Santos ; Rodrigues, Liliana. "Identification of efflux inhibitors through a drug repositioning strategy in Candida albicans.". In final stages of preparation to be submitted to Frontiers in Cellular and Infection Microbiology (2025):
  7. Silva, Joana Moreira da; Menezes, Juliana; Fernandes, Laura; Marques, Cátia; Costa, Sofia Santos ; Amaral, Andreia; Pomba, Constança. "Evaluation and Molecular m-Mechanisms of Multidrug-Resistant Bacteria in Small Animal Veterinary Practices in Portugal". Frontiers in Cellular and Infection Microbiology (2025):
    Open access • Accepted
  8. Serrano, Isa; Mil-Homens, Dalila; Pires, Rita; Bonifácio, Vasco; Guerreiro, Joana F; Cunha, Eva; Costa, Sofia Santos ; Tavares, Luís; Oliveira, Manuela. "In vivo antimicrobial activity of Nisin Z against S. aureus, and polyurea pharmadendrimer PUREG4OEI48 against P. aeruginosa from diabetic foot infections". Antibiotics (2025):
    Open access • Under revision
  9. Francisco, Moisés; Belas, Adriana; Costa, Sofia Santos ; Menezes, Juliana; Ramos, Jorge; Couto, Isabel; Viveiros, Miguel; Pomba, Constança. "Molecular Patterns and Antimicrobial Resistance Characterization of Salmonella enterica Non-Typhoidal from Human, Food, and Environment Samples Isolated in Luanda, Angola". Zoonotic Diseases 4 (2024): 259-270. https://doi.org/10.3390/zoonoticdis4040022.
    Open access • Published • 10.3390/zoonoticdis4040022
  10. Moreira da Silva, Joana; Menezes, Juliana; Fernandes, Laura; Costa, Sofia Santos; Amaral, Andreia; Pomba, Constança. "Carbapenemase-producing Enterobacterales strains causing infections in companion animals—Portugal". Microbiology Spectrum 12 (2024): e0341623. http://dx.doi.org/10.1128/spectrum.03416-23.
    Open access • Published • 10.1128/spectrum.03416-23
  11. Garrine, Marcelino; Andrade, Mariana; Neves, Joana; Mandomando, Inácio; Couto, Isabel; Costa, Sofia Santos . "Exploring the virulence potential of Staphylococcus aureus CC121 and CC152 lineages related to paediatric community-acquired bacteraemia in Manhiça, Mozambique". Scientific Reports 14 (2024): 10758. https://doi.org/10.1038/s41598-024-61345-3.
    Open access • Published • 10.1038/s41598-024-61345-3
  12. Moreira da Silva, Joana; Menezes, Juliana; Fernandes, Laura; Marques, Cátia; Costa, Sofia Santos; Timofte, Dorina; Amaral, Andreia; Pomba, Constança. "Dynamics of blaOXA-23 gene transmission in Acinetobacter spp. from contaminated veterinary environmental surfaces: An Emerging One Health threat?". Journal of Hospital Infection 146 (2024): 116-124. http://dx.doi.org/10.1016/j.jhin.2024.02.001.
    Published • 10.1016/j.jhin.2024.02.001
  13. Leal, Marta; Morais, Catarina; Ramos, Bárbara; Abrantes, Patrícia; Pomba, Constança; Costa, Sofia Santos; Couto, Isabel. "O impacto do efluxo na suscetibilidade reduzida a biocidas e resistência a fluoroquinolonas em Staphylococcus pseudintermedius". Anais do Instituto de Higiene e Medicina Tropical 22 (2024): 87-92. https://anaisihmt.com/index.php/ihmt/article/view/460.
    Open access • Published
  14. Garrine, Marcelino; Costa, Sofia Santos; Messa, Augusto; Massora, Sérgio; Vubil, Delfino; Ácacio, Sozinho; Nhampossa, Tacilta; et al. Corresponding author: Couto, Isabel. "Antimicrobial resistance and clonality of Staphylococcus aureus causing bacteraemia in children admitted to the Manhiça District Hospital, Mozambique, over two decades". Frontiers in Microbiology 14 (2023): 1208131. http://dx.doi.org/10.3389/fmicb.2023.1208131.
    Open access • Published • 10.3389/fmicb.2023.1208131
  15. Morais, Catarina; Costa, Sofia Santos; Leal, Marta; Ramos, Bárbara; Andrade, Mariana; Ferreira, Carolina; Abrantes, Patrícia; Pomba, Constança; Couto, Isabel. "Genetic diversity and antimicrobial resistance profiles of Staphylococcus pseudintermedius associated with skin and soft-tissue infections in companion animals in Lisbon, Portugal". Frontiers in Microbiology 14 (2023): 1167834. http://dx.doi.org/10.3389/fmicb.2023.1167834.
    Open access • Published • 10.3389/fmicb.2023.1167834
  16. Leal, Marta; Morais, Catarina; Ramos, Bárbara; Pomba, Constança; Abrantes, Patrícia; Costa, Sofia Santos; Couto, Isabel. "Exploring efflux as a mechanism of reduced susceptibility towards biocides and fluoroquinolones in Staphylococcus pseudintermedius". Animals 13 (2023): 1270. doi: 10.3390/ani13071270.
    Open access • Published
  17. Garrine, Marcelino; Quintó, Llorenç; Costa, Sofia Santos; Messa, Augusto; Massinga, Arsénia J.; Vubil, Delfino; Nhampossa, Tacilta; et al. Corresponding author: Mandomando, Inácio. "Epidemiology and clinical presentation of community-acquired Staphylococcus aureus bacteraemia in children under 5 years of age admitted to the Manhiça District Hospital, Mozambique, 2001–2019". European Journal of Clinical Microbiology & Infectious Diseases 42 (2023): 653-659. http://dx.doi.org/10.1007/s10096-023-04580-2.
    Published • 10.1007/s10096-023-04580-2
  18. Ferreira, Carolina; Abrantes, Patrícia; Costa, Sofia Santos; Viveiros, Miguel; Couto, Isabel. "Occurrence and variability of the efflux pump gene norA across the Staphylococcus Genus". International Journal of Molecular Sciences 23 23 (2022): 15306. http://dx.doi.org/10.3390/ijms232315306.
    Open access • Published • 10.3390/ijms232315306
  19. Andrade, Mariana; Oliveira, Ketlyn; Morais, Catarina; Abrantes, Patrícia; Pomba, Constança; Rosato, Adriana E.; Couto, Isabel; Costa, Sofia Santos. "Virulence potential of biofilm-producing Staphylococcus pseudintermedius, Staphylococcus aureus and Staphylococcus coagulans causing skin infections in companion animals". Antibiotics 11 10 (2022): 1339. http://dx.doi.org/10.3390/antibiotics11101339.
    Open access • Published • 10.3390/antibiotics11101339
  20. Moreira da Silva, Joana; Menezes, Juliana; Mendes, Gabriel; Santos Costa, Sofia; Caneiras, Cátia; Poirel, Laurent; Amaral, Andreia J.; Pomba, Constança. "KPC-3-producing Klebsiella pneumoniae sequence type 392 from a dog’s clinical isolate in Portugal". Microbiology Spectrum 10 (2022): e0089322. http://dx.doi.org/10.1128/spectrum.00893-22.
    Open access • Published • 10.1128/spectrum.00893-22
  21. Costa, Sofia Santos; Ribeiro, Rute; Serrano, Maria; Oliveira, Ketlyn; Ferreira, Carolina; Leal, Marta; Pomba, Constança; Couto, Isabel. "Staphylococcus aureus causing skin and soft tissue infections in companion animals: antimicrobial resistance profiles and clonal lineages". Antibiotics 11 5 (2022): 599. http://dx.doi.org/10.3390/antibiotics11050599.
    Open access • Published • 10.3390/antibiotics11050599
  22. Costa, Sofia Santos; Ferreira, Carolina; Ribeiro, Rute; Feßler, Andrea T.; Schink, Anne-Kathrin; Kadlec, Kristina; Kaspar, Heike; et al. Corresponding author: Couto, Isabel. "Proposal of Epidemiological Cutoff Values for Apramycin 15 µg and Florfenicol 30 µg Disks Applicable to Staphylococcus aureus". Microbial Drug Resistance 27 (2021): 1555-1559. http://dx.doi.org/10.1089/mdr.2020.0402.
    Open access • Published • 10.1089/mdr.2020.0402
  23. Costa, Sofia Santos; Oliveira, Valéria; Serrano, Maria; Pomba, Constança; Couto, Isabel. "Phenotypic and Molecular Traits of Staphylococcus coagulans Associated with Canine Skin Infections in Portugal". Antibiotics 10 5 (2021): 518. https://doi.org/10.3390/antibiotics10050518.
    Open access • Published • 10.3390/antibiotics10050518
  24. Ferreira, Carolina; Costa, Sofia Santos; Serrano, Maria; Oliveira, Ketlyn; Trigueiro, Graça; Pomba, Constança; Couto, Isabel. "Clonal lineages, antimicrobial resistance, and PVL carriage of Staphylococcus aureus associated to skin and soft-tissue infections from ambulatory patients in Portugal". Antibiotics 10 4 (2021): 345. http://dx.doi.org/10.3390/antibiotics10040345.
    Open access • Published • 10.3390/antibiotics10040345
  25. Tozar, Tatiana; Santos Costa, Sofia; Udrea, Ana-Maria; Nastasa, Viorel; Couto, Isabel; Viveiros, Miguel; Pascu, Mihail Lucian; Romanitan, Mihaela Oana. "Anti-staphylococcal activity and mode of action of thioridazine photoproducts". Scientific Reports 10 1 (2020): http://dx.doi.org/10.1038/s41598-020-74752-z.
    Open access • Published • 10.1038/s41598-020-74752-z
  26. Costa, Sofia Santos; Sobkowiak, Benjamin; Parreira, Ricardo; Edgeworth, Jonathan D.; Viveiros, Miguel; Clark, Taane G.; Couto, Isabel. "Genetic diversity of norA, coding for a main efflux pump of Staphylococcus aureus". Frontiers in Genetics 9 (2019): 710. http://dx.doi.org/10.3389/fgene.2018.00710.
    Open access • Published • 10.3389/fgene.2018.00710
  27. Cremers, Niels; Belas, Adriana; Costa, Sofia Santos ; Couto, Isabel; de Rooster, Hilde; Pomba, Constança. "In vitro antimicrobial efficacy of two medical grade honey formulations against common high-risk meticillin-resistant staphylococci and Pseudomonas spp. pathogens". Veterinary Dermatology 31 (2019): 90-96. http://dx.doi.org/10.1111/vde.12811.
    Published • 10.1111/vde.12811
  28. Francisco, Moisés; Costa, Sofia Santos; Belas, Adriana; Ramos, Jorge; Couto, Isabel; Pomba, Constança; Viveiros, Miguel. "First report on antimicrobial resistance and molecular characterisation of Salmonella enterica serotype Typhi isolated from human specimens in Luanda, Angola". Journal of Global Antimicrobial Resistance 13 (2018): 246-249. https://doi.org/10.1016/j.jgar.2018.02.001.
    Published • 10.1016/j.jgar.2018.02.001
  29. Costa, Sofia Santos; Couto, Isabel. "The Second GHTM Antimicrobial Resistance Awareness Day [In PT]". Anais do Instituto de Higiene e Medicina Tropical 17 (2018): 83-86.
    Published
  30. Cannalire, Rolando; Machado, Diana; Felicetti, Tommaso; Costa, Sofia Santos; Massari, Serena; Manfroni, Giuseppe; Barreca, Maria Letizia; et al. Corresponding author: Cecchetti, Violetta. "Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium". European Journal of Medicinal Chemistry 140 (2017): 321-330. https://doi.org/10.1016/j.ejmech.2017.09.014.
    Published • 10.1016/j.ejmech.2017.09.014
  31. Costa, Sofia Santos; Viveiros, Miguel; Pomba, Constança; Couto, Isabel. "Active antimicrobial efflux in Staphylococcus epidermidis: building up of resistance to fluoroquinolones and biocides in a major opportunistic pathogen.". Journal of Antimicrobial Chemotherapy 73 2 (2017): 320-324. https://doi.org/10.1093/jac/dkx400.
    Open access • Published • 10.1093/jac/dkx400
  32. Khemiri, Monia; Alhusain, Ali Akrout; Abbassi, Mohamed Salah; Ghaieb, Houyem El; Costa, Sofia Santos; Belas, Adriana; Pomba, Constança; Hammami, Salah. "Clonal spread of methicillin-resistant Staphylococcus aureus-t6065-CC5-SCCmecV-agrII in a Libyan hospital". Journal of Global Antimicrobial Resistance 10 (2017): 101-105. https://doi.org/10.1016/j.jgar.2017.04.014.
    Published • 10.1016/j.jgar.2017.04.014
  33. Machado, Diana; Fernandes, Laura; Costa, Sofia Santos; Cannalire, Rolando; Manfroni, Giuseppe; Tabarrini, Oriana; Couto, Isabel; Sabatini, Stefano; Viveiros, Miguel. "Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli". PeerJ 5 (2017): e3168-e3168. https://doi.org/10.7717/peerj.3168.
    Open access • Published • 10.7717/peerj.3168
  34. Silva, Lande, Jr.; Carrion, Lillian Lucas; von Groll, Andrea; Costa, Sofia Santos; Junqueira, Elisabete; Ramos, Daniela Fernandes; Cantos, Jessica; et al. "In vitro and in silico analysis of the efficiency of tetrahydropyridines as drug efflux inhibitors in Escherichia coli". International Journal of Antimicrobial Agents 49 3 (2017): 308-314. https://doi.org/10.1016/j.ijantimicag.2016.11.024.
    Published • 10.1016/j.ijantimicag.2016.11.024
  35. Costa, Sofia Santos; Couto, Isabel. "The First GHTM Antimicrobial Resistance Awareness Day [In PT]". Anais do Instituto de Higiene e Medicina Tropical 16 (2017): 61-63. http://anaisihmt.com/index.php/ihmt/article/view/29.
    Open access • Published
  36. Costa, Sofia Santos; Palma, Cláudia; Kadlec, Kristina; Fessler, Andrea T.; Viveiros, Miguel; Melo-Cristino, José; Schwarz, Stefan; Couto, Isabel. "Plasmid-borne antimicrobial resistance of Staphylococcus aureus isolated in a hospital in Lisbon, Portugal". Microbial Drug Resistance 22 8 (2016): 617-626. https://doi.org/10.1089/mdr.2015.0352.
    Published • 10.1089/mdr.2015.0352
  37. Costa, Sofia Santos; Lopes, Elizeth; Azzali, Elisa; Machado, Diana; Coelho, Tatiane; Silva, Pedro Eduardo Almeida; Viveiros, Miguel; Pieroni, Marco; Couto, Isabel. "An experimental model for the rapid screening of compounds with potential use against mycobacteria". Assay and Drug Development Technologies 14 9 (2016): 524-534. https://doi.org/10.1089/adt.2016.752.
    Published • 10.1089/adt.2016.752
  38. Pieroni, Marco; Machado, Diana; Azzali, Elisa; Costa, Sofia Santos; Couto, Isabel; Costantino, Gabriele; Viveiros, Miguel. "Rational design and synthesis of thioridazine analogues as enhancers of the antituberculosis therapy". Journal of Medicinal Chemistry 58 15 (2015): 5842-5853. http://dx.doi.org/10.1021/acs.jmedchem.5b00428.
    Published • 10.1021/acs.jmedchem.5b00428
  39. Machado, Diana; Cannalire, Rolando; Costa, Sofia Santos; Manfroni, Giuseppe; Tabarrini, Oriana; Cecchetti, Violetta; Couto, Isabel; Viveiros, Miguel; Sabatini, Stefano. "Boosting effect of 2-phenylquinoline efflux inhibitors in combination with macrolides against Mycobacterium smegmatis and Mycobacterium avium". ACS Infectious Diseases 11 (2015): 593-603. http://dx.doi.org/10.1021/acsinfecdis.5b00052.
    Published • 10.1021/acsinfecdis.5b00052
  40. Cabral, Vanessa; Luo, Xuan; Junqueira, Elisabete; Costa, Sofia Santos; Mulhovo, Silva; Duarte, Aida; Couto, Isabel; Viveiros, Miguel; Ferreira, Maria-José Umbelino. "Enhancing activity of antibiotics against Staphylococcus aureus: Zanthoxylum capense constituents and derivatives.". Phytomedicine 22 (2015): 469-476. http://doi.org/10.1016/j.phymed.2015.02.003.
    Published • 10.1016/j.phymed.2015.02.003
  41. Costa, Sofia Santos; Viveiros, Miguel; Rosato, Adriana E.; Melo-Cristino, José; Couto, Isabel. "Impact of efflux in the development of multidrug resistance phenotypes in Staphylococcus aureus.". BMC Microbiology 15 (2015): 232. https://doi.org/10.1186/s12866-015-0572-8.
    Open access • Published • 10.1186/s12866-015-0572-8
  42. Lobo, Maria Luísa; Santos Costa, Sofia; Pinto Junior, Vitor Laerte; Salgueiro, Patrícia; Tavanez, João Paulo; Campino, Lenea. "Synopsys of the 3rd National Congress of Tropical Medicine and 1st Lusophone Congress of Vector-Borne Diseases [In PT]". Anais do Instituto de Higiene e Medicina Tropical 14 (2015): 47-56. http://anaisihmt.com/index.php/ihmt/article/view/146.
    Open access • Published
  43. de Carvalho, Carla C.C.R.; Costa, Sofia Santos; Fernandes, Pedro; Couto, Isabel; Viveiros, Miguel. "Membrane transport systems and the biodegradation potential and pathogenicity of genus Rhodococcus". Frontiers in Physiology 5 (2014): 133. https://doi.org/10.3389/fphys.2014.00133.
    Open access • Published • 10.3389/fphys.2014.00133
  44. Costa, Sofia Santos; Junqueira, Elisabete; Palma, Cláudia; Viveiros, Miguel; Melo-Cristino, José; Amaral, Leonard; Couto, Isabel. "Resistance to antimicrobials mediated by efflux pumps in Staphylococcus aureus". Antibiotics 2 1 (2013): 83-99. https://doi.org/10.3390/antibiotics2010083.
    Open access • Published • 10.3390/antibiotics2010083
  45. Costa, Sofia Santos; Viveiros, Miguel; Amaral, Leonard; Couto, Isabel. "Multidrug efflux pumps in Staphylococcus aureus: an Update.". The open microbiology journal 7 (2013): 59-71. https://doi.org/10.2174/1874285801307010059.
    Open access • Published • 10.2174/1874285801307010059
  46. Costa, Sofia Santos; Mourato, Cláudia; Viveiros, Miguel; Melo-Cristino, José; Couto, Isabel. "Description of plasmid pSM52, harbouring the gene for the Smr efflux pump, and its involvement in resistance to biocides in a meticillin-resistant Staphylococcus aureus strain". International Journal of Antimicrobial Agents 41 5 (2013): 490-492. https://doi.org/10.1016/j.ijantimicag.2013.01.003.
    Published • 10.1016/j.ijantimicag.2013.01.003
  47. Spengler, Gabriella; Rodrigues, Liliana; Martins, Ana; Martins, Marta; McCusker, Matthew; Cerca, Pedro; Machado, Lisa; et al. "Genetic response of Salmonella enterica serotype Enteritidis to thioridazine rendering the organism resistant to the agent". International Journal of Antimicrobial Agents 39 1 (2012): 16-21. https://doi.org/10.1016/j.ijantimicag.2011.08.013.
    Published • 10.1016/j.ijantimicag.2011.08.013
  48. Costa, Sofia Santos; Falcão, Celeste; Viveiros, Miguel; Machado, Diana; Martins, Marta; Melo-Cristino, José; Couto, Isabel. "Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus". BMC Microbiology 11 (2011): 241. https://doi.org/10.1186/1471-2180-11-241.
    Open access • Published • 10.1186/1471-2180-11-241
  49. Martins, Marta; Viveiros, Miguel; Couto, Isabel; Costa, Sofia Santos; Pacheco, Teresa; Fanning, Séamus; Pagès, Jean-Marie; Amaral, Leonard. "Identification of efflux pump-mediated multidrug-resistant bacteria by the ethidium bromide-agar cartwheel method". In Vivo 25 2 (2011): 171-178. http://www.scopus.com/inward/record.url?eid=2-s2.0-79954994775&partnerID=MN8TOARS.
    Published
  50. Costa, Sofia Santos; Ntokou, Eleni; Martins, Ana; Viveiros, Miguel; Pournaras, Spyros; Amaral, Leonard; Couto, Isabel. "Identification of the plasmid-encoded qacA efflux pump gene in meticillin-resistant Staphylococcus aureus (MRSA) strain HPV107, a representative of the MRSA Iberian clone.". International Journal Of Antimicrobial Agents 36 6 (2010): 557-561. https://doi.org/10.1016/j.ijantimicag.2010.08.006.
    Published • 10.1016/j.ijantimicag.2010.08.006
  51. Spengler, Gabriella; Martins, Ana; Schelz, Zsuzsanna; Rodrigues, Liliana; Aagaard, Lone; Martins, Marta; Costa, Sofia Santos ; et al. "Characterization of intrinsic efflux activity of Enterococcus faecalis ATCC29212 by a semi-automated ethidium bromide method". In Vivo 23 1 (2009): 81-87. https://unl.elsevierpure.com/en/publications/c61939f9-dbe3-4718-8929-fb0f970be727.
    Published
  52. Couto, Isabel; Costa, Sofia Santos; Viveiros, Miguel; Martins, Marta; Amaral, Leonard. "Efflux-mediated response of Staphylococcus aureus exposed to ethidium bromide". Journal of Antimicrobial Chemotherapy 62 3 (2008): 504-513. http://doi.org/10.1093/jac/dkn217.
    Published • 10.1093/jac/dkn217
Thesis / Dissertation
  1. Costa, Sofia Santos. "Efflux pump activity in drug resistance of Staphylococcus aureus.". PhD, Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, 2013.
  2. Costa, Sofia Santos. "Phenotypic and genotypic characterizations of a Staphylococcus aureus strain adapted to ethidium bromide". Master, Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, 2008.
  3. Costa, Sofia Santos. "Production of recombinant proteins". Degree, Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, 2004.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025/04 Identification of efflux inhibitors through a drug repurposing strategy in Candida albicans. ESCMID Global 2025 - Congress of the European Society of Clinical Microbiology and Infectious Diseases
European Society of Clinical Microbiology and Infectious Diseases (Wien, Austria)
2024/11/25 Galleria mellonella: um modelo in vivo fidedigno para avaliar a eficácia de fármacos para a terapêutica de infeções provocadas por estafilococos. Microbiologia 2024 (Online Conference)
Sociedade Portuguesa de Microbiologia, Sociedade Brasileira de Microbiologia
2024/11/18 Drug repurposing for efflux and biofilm inhibition as a strategy to fight antimicrobial resistance, a silent pandemic NOVAHealth VII International Conference “Tackling Pandemics: Strategies for Prevention, Preparedness and Response”
NOVA Health (Lisbon, Portugal)
2024/08/19 Galleria mellonella as a reliable in vivo model to evaluate repurposed drugs for Staphylococcus infection therapeutics 19th International Symposium of Staphylococci and Staphylococcal Infections
Australian Society for Antimicrobials (Perth, Australia)
2024/08/19 New candidate drugs for repurposing as efflux inhibitors and antibiofilm agents against antimicrobial-resistant Staphylococcus aureus and Staphylococcus epidermidis. 19th International Symposium of Staphylococci and Staphylococcal Infections
Australian Society for Antimicrobials (Perth, Australia)
2024/04/30 New candidate drugs for repurposing as efflux inhibitors and antibiofilm agents against antimicrobial-resistant Staphylococcus aureus and Staphylococcus epidermidis. 34th European Congress on Clinical Microbiology and Infectious Diseases (ECCMID)
European Society of Clinical Microbiology and Infectious Diseases (Barcelona, Spain)
2024/03/01 O papel das bombas de efluxo na resistência aos antimicrobianos em isolados clínicos de Neisseria gonorrhoeae. II Congresso BiomedLab
Associação Portuguesa de Ciências Biomédica laboratoriais (Coimbra, Portugal)
2023/12/08 Characterization of biofilm formation of bacteria associated with the midgut of Anopheles mosquito vector of malaria. National Congress of Microbiology and Biotechnology (MicroBiotec23), Covilhã, Portugal
Sociedade Portuguesa de Microbiologia, Sociedade Portuguesa de Biotecnologia (Covilhã, Portugal)
2023/04/20 Implementation of the Galleria mellonella infection model at GHTM/IHMT-NOVA. 6th National Congress of Tropical Medicine (CNTM)
Instituto de Higiene e Medicina Tropical, Universidade NOVA de Lisboa (Lisbon, Portugal)
2023/04/20 Epidemiology and clonality of Staphylococcus aureus bacteraemia in children <5 years of age admitted to the Manhiça district hospital, Mozambique, 2001-2019 6th National Congress of Tropical Medicine (CNTM)
Instituto de Higiene e Medicina Tropical, Universidade NOVA de Lisboa (Lisbon, Portugal)
2023/04/20 Drug repurposing as an approach to bypass efflux mediated resistance in Neisseria gonorrhoeae 6th National Congress of Tropical Medicine (CNTM)
Instituto de Higiene e Medicina Tropical, Universidade NOVA de Lisboa (Lisbon, Portugal)
2023/04/20 Implementation of the Galleria mellonella infection model at GHTM/IHMT-NOVA 6th National Congress of Tropical Medicine (CNTM)
Instituto de Higiene e Medicina Tropical, Universidade NOVA de Lisboa (Lisbon, Portugal)
2022/09/20 Antimicrobial Resistance in a One Health Perspective Webinar - International Microorganism Day
Universidade da Beira Interior
2022/04/23 Emergence of staphylococcal non-wild-type populations to biocides in a One Health perspective: are there reasons for concern? Selected for Mini-Oral Flash presentation at 32nd European Congress on Clinical Microbiology and Infectious Diseases (ECCMID)
European Society of Clinical Microbiology and Infectious Diseases (Lisbon/Online, Portugal)
2021/01/10 Antimicrobial resistance and molecular typing of Staphylococcus aureus causing bacteraemia in children ages less than 5 years in Southern Mozambique. XII IHMT Scientific Day
IHMT-NOVA (Online, Portugal)
2018/04/23 Emergence of non-wild-type populations towards biocides and antibiotic resistance in Staphylococcus epidermidis colonizing veterinary staff and students 28th European Congress on Clinical Microbiology and Infectious Diseases (ECCMID)
ESCMID (Madrid, Spain)
2017/11/15 Antibiotic and biocide resistance in Staphylococcus epidermidis colonizing humans in close contact with animals First GHTM Antimicrobial Resistance Awareness Day
GHTM, IHMT-NOVA (Lisbon, Portugal)
2017/07/05 Microbial multiresistance in the era of global challenges - an urgent need for new approaches and technologies Encontro Ciência 2017
(Lisbon, Portugal)
2017/06/12 Emergent public health risk of antimicrobial resistance transfer from companion animals: methicillin-resistant Staphylococcus epidermidis and Staphylococcus haemolyticus 2nd International Caparica Conference in Antimicrobial Resistance
(Caparica, Portugal)
2016/04/10 Antimycobacterial and efflux inhibitory activity of 2-aminothiazole lead compound against Mycobacterium tuberculosis European Congress on Clinical Microbiology and Infectious Diseases (ECCMID)
(Amsterdam, Netherlands)
2015/12/11 Mycobacterium smegmatis model for the rapid screening of new compounds with efflux inhibitory and antimycobacterial activity National Congress of Microbiology and Biotechnology
MicroBiotec15 (Évora, Portugal)
2013/04/23 Clinical relevance of efflux systems to antimicrobial resistance in Staphylococcus aureus 2nd National Congress of Tropical Medicine
IHMT-NOVA (Lisbon, Portugal)
2011/12/11 Clinical relevance of efflux systems to antimicrobial resistance in Staphylococcus aureus 2nd Scientific Day of IHMT
IHMT-NOVA (Lisbon, Portugal)
2011/12/06 Exploring the contribution on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus. Working group meeting of the COST ACTION BM0701
(Brussels, Belgium)
2010/07/07 Importance of efflux systems on the resistance to fluoroquinolones in Staphylococcus aureus. Working group meeting of the COST ACTION BM0701
Jacobs University Bremen (Bremen, Germany)
2008/07/17 Phenotypic and genotypic characterization of a Staphylococcus aureus strain adapted to ethidium bromide. Journal Club CMDT-LA
IHMT-NOVA (Lisbon, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2024/09 - Current Galleria mellonella as an infection model for Leishmania sp.
Co-supervisor of Eunice Kaizeler
 Parasitologia Médica (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2024/09 - Current Characterization of the resistance molecular profile and phylogenetic analysis of Neisseria gonorrhoeae
Co-supervisor of Amélia Marinheiro
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2024/09 - Current Characterization of the efluxome of Staphylococcus haemolyticus and Staphylococcus hominis
Co-supervisor of Diana Martinho
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2024/09 - Current Identification of drugs for repurposing as efflux and biofilm inhibitors against clinically-relevant pathogens
Supervisor of Pedro Rita
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2024/09 - Current Study of the efflux-biofilm relation: new methods for evaluation of the efflux activity of bacterial cells within biofilms
Supervisor of Matilde Nunes
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2024/09 - Current The role of Pseudomonas-Serratia interactions in crafting biofilms barriers against Plasmodium infection in Anopheles mosquitos
Co-supervisor of Margarida Reçonha Marques (FCT Grantee)
 Doenças Tropicais e Saúde Global (PhD)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2024/09 - Current Evaluation of the antimicrobial activity of synthetic thiazolidinones and their modulating effect on antibacterial resistance
Co-supervisor of Humberto Barreto (CPNq Post-Doc Grantee - Mobility program)
Universidade Federal do Piauí, Brazil
2023/12/01 - Current Molecular characterization, etiological agents identification and associated factors associated to neonatal sepsis in Hospital Central de Maputo, Mozambique
Supervisor of Lena Coutinho (Centro Ciência LP - FCT grantee)
Ciências Biomédicas (PhD)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2023/10 - Current Unraveling the efflux-mediated response to antimicrobials in S. pseudintermedius, a major animal pathogen
Co-supervisor of Marta Sofia Pires Leal (FCT Grantee)
 Ciências Biomédicas (PhD)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2023/04/01 - Current Drug repurposing for efflux and biofilm inhibition in staphylococci
Supervisor of Mariana Andrade (FCT Grantee)
 Ciências Biomédicas (PhD)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2021/10/01 - Current The staphylococcal effluxome: role in antimicrobial resistance and virulence
Co-supervisor of Carolina Ferreira (FCT Grantee)
 Ciências Biomédicas (PhD)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2021/01/01 - Current Carbapenem resistance Enterobacteriaceae transmission in the community: who is amplifying resistance?
Co-supervisor of Joana Silva (FCT Grantee)
 Ciências Biomédicas (PhD)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2018/09 - Current Antimicrobial resistance in staphylococci causing skin and soft tissue infections
Co-supervisor of Catarina Morais (FCT Grantee)
 Ciências Biomédicas (PhD)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2023/09/01 - 2025/04/01 Evaluation of the activity and efficacy of drugs for repurposing against Staphylococcus aureus and Staphylococcus epidermidis
Supervisor of Maria Ana Bento
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2023/09/01 - 2025/03/28 Identification of efflux inhibitors in Candida albicans by a drug repurposing strategy
Co-supervisor of Débora Alexandra Dias Marques
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2023/10/01 - 2025/02/27 Estudo do efluxo na resistência a tetraciclinas em <i>Staphylococcus pseudintermedius</i>
Co-supervisor of Ana Santos
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2022/10/01 - 2025/01/27 Isolation of Pseudomonas spp. from the Anopheles mosquitos midgut and characterization of their effect on Plasmodium development
Co-supervisor of Joana Antunes
 Parasitologia Médica (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2024/06 - 2024/12 Development of laboratory and bioinformatic protocols for identification of pathogenic agents and analysis of antimicrobial resistance in residual waters in the context of limited resources
Co-supervisor of Filomena Manjate (Calouste Gulbenkian Foundation Grantee - ENVOLVE Ciência PALOP)
Centro de Investigação em Saúde de Manhiça, Mozambique
2022/10/01 - 2024/07 Development and optimization of a Galleria mellonella infection model for virulence assays and drug evaluation
Supervisor of Telma Rodrigues
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2022/10/01 - 2024/06 Evaluation of in vitro activity of amlodipine and other ionic channel blockers in Neisseria gonorrhoeae
Co-supervisor of João Fernandes
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2022/10/01 - 2024/05 The role of efflux pumps on antimicrobial resistance in Neisseria gonorrhoeae
Co-supervisor of Teresa Paulino
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2023/08/16 - 2024/03/15 Exploring efflux inhibiton to counteract antimicrobial resistance and biofilms in staphylococci
Supervisor of Joana Neves (BI grantee)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2017/12/12 - 2024/01/25 Epidemiological, phenotypic and molecular profile of Staphylococcus aureus causing bacteraemia in children younger than 5 years in Manhiça district, Mozambique, 2001- 2019
Co-supervisor of Marcelino Garrine
 Ciências Biomédicas (PhD)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2022/10/01 - 2023/12/20 Characterization of biofilm formation by bacteria associated with the midgut of Anopheles mosquito, vector of malaria
Co-supervisor of Margarida Reçonha Marques
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2023/01/23 - 2023/07/11 Experimental validation of new drugs for repurposing as efflux inhibitors in Staphylococcus aureus
Supervisor of Benjamim Carvalho
 Bioquímica (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021/08/01 - 2023/05/24 Evaluation of the microbiology safety of raspberries in irrigated greenhouse with residual and reused treated waters
Co-supervisor of Melanie Alves
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2021/09/10 - 2023/03/31 Drug repurposing for new efflux inhibitors and antibiofilm agents against Staphylococcus epidermidis
Supervisor of Joana Neves
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2021/09/01 - 2023/03/16 Characterization of the Staphylococcus aureus ATCC25923 transcriptome exposed to chlorhexidine
Co-supervisor of Paula Zacharias
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2021/09/01 - 2023/02/08 Drug repurposing against efflux-mediated resistance in Neisseria gonorrhoeae
Co-supervisor of Inês Vítor
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2021/09/01 - 2023/02/07 Drug repurposing against efflux-mediated resistance in Gram-negative bacteria
Co-supervisor of Ana Mendes
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2021/09/10 - 2023/02/01 Identification in silico and experimental validation of new efflux inhibitors and antibiofilm agents in Staphylococcus aureus
Supervisor of Carolina Antunes
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2020/09 - 2022/03/21 Evaluation of efflux activity in Staphylococcus pseudintermedius and its relation with reduced susceptibility to antimicrobials
Co-supervisor of Marta Leal
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2020/08 - 2022/02/07 Study of the virulence potential of Staphylococcus pseudintermedius associated with skin and soft tissue infections in companion animals
Supervisor of Mariana Andrade
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2020/09 - 2022/01/25 Evaluation of the virulence potential of Staphylococcus aureus associated with skin and soft tissue infections
Supervisor of Ketlyn Oliveira
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/10 - 2021/12/21 Estudo do efluxo e de outros mecanismos na resistência a fluoroquinolonas em Staphylococcus pseudintermedius
Co-supervisor of Bárbara Ramos
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2018/10 - 2020/02/17 Molecular characterization of staphylococci associated with skin and soft tissue infections
Supervisor of Maria Serrano
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2018/09 - 2020/01/27 Antimicrobial resistance in staphylococci causing infection in pets
Co-supervisor of Rute Ribeiro
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2018/09 - 2020/01 Resistance to biocides and topical antibiotics in staphylococcus aureus of human origin
Co-supervisor of Carolina Ferreira
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2018/09 - 2019/12/19 Resistance to biocides and antibiotics in staphylococci causing infection in pets
Supervisor of Valéria Oliveira
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2016/09 - 2018/04 Influence of efflux activity in biofilm production by Staphylococcus epidermidis
Co-supervisor of Cláudia Santos
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2016/09 - 2018 Characterization of Staphylococcus epidermidis plasmids and correlation with efflux-mediated antimicrobial resistance
Co-supervisor of Frederico Holtreman
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2015/09 - 2017 Contribution of efflux to antimicrobial resistance in Staphylococcus epidermidis
Co-supervisor of Mafalda Rosa
 Ciências Biomédicas (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2014/09 - 2016 Development of new methodological stratetegies for evaluation of compounds with therapeutical potential against tuberculosis and other mycobacteriosis
Co-supervisor of Elizeth Lopes
 Microbiologia Médica (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2014/02 - 2014/06 Evaluation of efflux pump activity in bacteria
Co-supervisor of Diana Fajardo
 Erasmus exchange program - Jaggiellonian University, Krakow, Poland (Other)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2024/07/22 - 2024/07/26 2nd Summer School on Antimicrobial and Biocide Resistance (2024/07/22 - 2024/07/26)
Workshop (Co-organisor)
 Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Freie Universität Berlin Fachbereich Veterinärmedizin, Germany
2022/09/12 - 2022/09/15 Summer School on Antimicrobial Resistance (2022/09/12 - 2023/09/15)
Workshop (Co-organisor)
 Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2017/11/15 - 2021/11/20 GHTM Antimicrobial Resistance Awareness Day (annual) (2017/11/15 - 2023/11/20)
Symposium (Co-organisor)
 Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal
2016/04 - 2021 GHTM sessions - Seminars of the THOP Research group (2016/04)
Seminar (Member of the Organising Committee)
 Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal
2016/04/08 - 2016/04/09 Organizing Committee of the event "Open Day at IHMT" (2016/04/08 - 2016/04/09)
Other (Member of the Organising Committee)
 Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2015/12/11 - 2015/12/11 VI Scientific Day of IHMT-NOVA (2015/12/11 - 2015/12/11)
Meeting (Member of the Scientific Committee)
 Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2011 - 2012 Journal Club of the PhD students in Biomedical Sciences (2011 - 2012)
Seminar (Co-organisor)
 Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2003/10/16 - 2003/10/17 1st Forum of Chemistry (2003/10/16 - 2003/10/17)
Conference (Member of the Organising Committee)
 Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2025/02/26 - Current Course "Doctoral supervision"
Workshop
 Course "Doctoral supervision" organized by EUTOPIA Project
2025/01/08 - Current Curricular Unit "Pedagogical Innovation" (3 ECTS)
Other
 Curricular Unit "Pedagogical Innovation"
Centro de Excelência SAPIEN (South and Atlantic Pedagogical Innovation & Excellence Network), Portugal
2025/03/28 - 2025/03/28 ARGOS Workshop
Workshop
 ARGOS Workshop - Data Management Plan
Fundacao de Computacao Cientifica Nacional, Portugal
2025/03/18 - 2025/03/18 Workshop "Citizen Science"
Workshop
 Workshop "Citizen Science" , organized by the OPUS Consorcium
2024/12/03 - 2024/12/03 Promotional stand "Galleria mellonella Research Hub"
Exhibition
 NOVA Science & Innovation Day
Universidade Nova de Lisboa, Portugal
2024/09/27 - 2024/09/27 Scientific activities on AMR and the Galleria mellonella Research Hub
Exhibition
 European Researchers' Night 2024
2024/09/17 - 2024/09/17 Galleria mellonella Promotion Video @ event "Conexões LusoMicrobianas"
Symposium
 International Microorganism Day
Sociedade Portuguesa de Microbiologia, Portugal
2024/04/09 - 2024/04/11 EUTOPIA_health Workhop "Training programme on EU funding: i-ISO concept", organized by VUB University & NOVA University. Training workshop on how to apply to Europe Horizon funding.
Workshop
 Training programme on EU funding
Universidade Nova de Lisboa, Portugal

Vrije Universiteit Brussel, Belgium
2023/03/22 - 2023/12/31 Rede de Clubes Ciência Viva na Escola, em parceria com o Agrupamento de Escolas Nº2 de Elvas
Exhibition
 Scientic Visit to IHMT-NOVA - scientific activity "Let's look for antimicrobial resistant strains"
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2022/09/26 - 2022/09/27 Crash course "Utilization of the command line"
Workshop
Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2022/09/17 - 2022/09/17 Scientific activity "Board game: Science vs. Resistant bacteria"
Exhibition
 Microorganism International Day 2022
Sociedade Portuguesa de Microbiologia, Portugal
2021/11/22 - 2021/11/22 2º Think Tank Pfizer-NOVA
Meeting
 2º Think Tank Pfizer-NOVA
Universidade Nova de Lisboa, Portugal
2021/11/19 - 2021/11/19 I Webinar One Health Day - Antimicrobial Awareness Week
Seminar
 I Webinar “One Health Day - Antimicrobial Awareness Week”
Universidade Lusófona de Humanidades e Tecnologias, Portugal
2020/01/23 - 2020/01/23 Awareness raising to coaching methodologies in the supervision of MSc and PhD Thesis (4h)
Workshop
 Awareness raising to coaching methodologies in the supervision of MSc and PhD Thesis
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2019/09/27 - 2019/09/27 European Researchers' Night - science outreach action "Antimicrobial resistance: the role of biocides and the new weapon to the fight against superbugs" in the scope of the BIOSAFE project
Exhibition
 European Researchers' Night 2019
Universidade de Lisboa Museu Nacional de História Natural, Portugal
2019/09/17 - 2019/09/17 International Microorganism Day - Science outreach action "Did you know that antimicrobial resistance is not just about antibiotics and that old drugs can be repurposed to fight resistant bacteria?" in the scope of the BIOSAFE project
Exhibition
 International Microorganism Day
Portuguese Society of Microbiology, Portugal
2019/06/17 - 2019/06/17 Mini-Symposium "Biological insights into pathogenicity in staphylococci"
Symposium
 Mini-Symposium "Biological insights into pathogenicity in staphylococci"
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2019/06/03 - 2019/06/03 Science Fair at Escola EB Joaquim de Barros - Science outreach action
Exhibition
 Science Fair
Escola EB Joaquim de Barros, Portugal
2019/04/28 - 2019/05/03 Gordon Conference "Multi-drug efflux systems" 2019
Conference
 Gordon Conference "Multi-drug efflux systems"
2019/03/14 - 2019/03/14 3rd Meeting of the ONEIDA Consortium - An Omics network to prevent and control Infectious Diseases and Antimicrobial Resistance
Meeting
 3rd ONEIDA Meeting
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2018/12/03 - 2018/12/03 I International Conference NOVAhealth on Chronic Disease and Infection - Resistance to antibiotics: from prevention to control of infection in “One Health”
Conference
 I International Conference NOVAhealth on Chronic Disease and Infection
Universidade Nova de Lisboa, Portugal
2017/03/26 - 2017/03/31 Gordon Conference "Multi-drug efflux systems" 2017
Conference
 Gordon Conference "Multi-drug efflux systems"
2016/09/22 - 2016/09/23 Modulation and Climate Prediction in Health (12h)
Workshop
 Workshop "Modulation and Climate Prediction in Health"
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2016/01/11 - 2016/01/15 Molecular epidemiology of infectious and parasite diseases (40h)
Other
 Short Course "Molecular epidemiology of infectious and parasite diseases"
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2015/09/14 - 2015/09/16 Pathogen genomics and genetic epidemiology of infectious and parasite diseases (20h)
Other
 Short Course "Pathogen genomics and genetic epidemiology of infectious and parasite diseases"
London School of Hygiene & Tropical Medicine, United Kingdom
2014/11/20 - 2014/11/21 Host-pathogen interaction towards a personalized medicine (8h)
Seminar
 Seminar "Host-pathogen interaction towards a personalized medicine"
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2014/11/03 - 2014/11/04 Potable water: global acess, quality and microbiology (8h)
Seminar
 International Seminar "Potable water: global acess, quality and microbiology"
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2013/04/24 - 2013/04/26 Workshop "Genomic variation and different sequencing technologies" (2h) and "Transcriptome analysis" (4h). By Thomas D. Otto, Wellcome Trust Sanger Centre.
Workshop
 Workshop on Genomics and Transcriptomics
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2010/07/04 - 2010/07/10 Transport across membranes: multiple drug resistance, mechanims and new tools (40h)
Seminar
 462nd WE Heraeus Seminar "Transport across membranes: multiple drug resistance, mechanims and new tools"
Jacobs University Bremen, Germany
2007/03/03 - 2007/03/11 Systems approach to membrane proteins (40h) Workshop "Systems approach to membrane proteins "
University of Leeds Institute of Membranes and Systems Biology and the Astbury Centre, United Kingdom

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2025/04 Evaluation of the activity and efficacy of drugs candidate for repurposing against Staphylococcus aureus and Staphylococcus epidermidis
Supervisor
 Maria Ana Bento (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2024/12/06 Characterization of Lancefield Group C and G Streptococci Causing Invasive Infections in Humans and Genomic Analysis of Macrolide Resistance, Portugal
(Thesis) Main arguer
 Maria Inês Filipe Mendes (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2024/07 Development and optimization of an infection model in Galleria mellonella for pathogenicity assays
Supervisor
 Telma Rodrigues (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2023/03/31 Repurposing of drugs with activity against efflux and biofilm formation in Staphylococcus epidermidis
Supervisor
 Joana Neves (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2023/03/16 Characterization of the transcriptome of Staphylococcus aureus ATCC25923 exposed to clorhexidine
Supervisor
 Paula Zacharias (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2023/02/01 In silico identification and experimental validation of new drugs as efflux and biofilm inhibitors in Staphylococcus aureus
Supervisor
 Carolina Antunes (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2022/12/20 A new target inside an old molecule: glutamate amidation of peptidoglycan
(Thesis) Arguer
 Bárbara Gonçalves (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2022/02/07 Study of the virulence potential of Staphylococcus pseudintermedius associated with skin and soft tissue infections in companion animals
Supervisor
 Mariana Andrade (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2022/01/25 Evaluation of the virulence potential of Staphylococcus aureus associated with skin and soft tissue infections
Supervisor
 Ketlyn Oliveira (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2020/12/03 Antimicrobial potential of epigallocatechin-3-gallate from green tea against MRSA from the hospital and the community
(Thesis) Main arguer
 Ana Sofia Simões Zeferino (Master)
Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
2020/07/28 Genomic characterization of Streptococcus dysgalactiae subsp. equisimilis responsible for invasive infection in Man
(Thesis) Main arguer
 Ana Carolina Santos (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
2020/02/17 Molecular characterization of staphylococci associated with skin and soft tissue infections.
Supervisor
 Maria de Fátima Sabarigo Serrano (Master)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2019/12/19 Resistance to biocides and topical antibiotics in staphylococci causing infections in pets.
Supervisor
 Valéria Joaquina Henrique de Oliveira (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Association member

Society Organization name Role
2011 - Current European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Member
2008 - Current Portuguese Society of Microbiology (SPM) Member
2011 - 2016 American Society of Microbiology Member

Conference scientific committee

Conference name Conference host
2021/12/10 - 2021/12/10 XII IHMT Scientific Day Webinar

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2020/12/17 - Current Curricular Unit - Medical Bacteriology (practical lessons) Microbiologia Médica (Mestrado integrado) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2020/12/17 - Current Curricular Unit -General Microbiology (practical lessons) Ciências Biomédicas (Mestrado integrado) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2020/10/15 - Current Curricular Unit: Applications in Medical Microbiology (laboratory tutorial) Ciências Biomédicas (Doutoramento) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2016/01 - Current Curricular Unit: Prevention and therapeutics of infectious diseases (practical lessons) Microbiologia Médica (Mestrado) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2014/06 - Current Curricular Unit: Molecular Diagnostic in Bacteriology and Mycology (theoretical-practical lessons) Microbiologia Médica (Mestrado) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2013/07 - Current Curricular Unit: Mechanisms of Resistance to Antibiotics (Lecture "Efflux-mediated resistance in bacteria" and practical lessons) Ciências Biomédicas (Mestrado) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2008/04 - Current Curricular Unit: Mechanisms of Resistance to Antibiotics (Lecture "Efflux-mediated resistance in bacteria", "Resistance to non-antibiotic compounds" and "Biofilms"; Practical lessons) Microbiologia Médica (Mestrado) Universidade Nova de Lisboa, Portugal
2020/10/26 - 2021/10/26 Curricular Unit: Disease Impact and its determinants (Lectures "Diagnostic Methods in Microbiology", "Staphylococci as agents of infection in humans and animals") Doenças Tropicais e Saúde Global (Doutoramento) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2018/06 - 2019/06 Advance Training Program for Laboratory Technicians. Mozambique Health Minitry/IHMT-NOVA: theoretical-pratical lessons on "Gram-negative and Gram-positive bacteria" and "Molecular typing techniques" (Outros) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2018/04/01 - 2018/04/08 Curricular Unit: Applications in Medical Microbiology (laboratory tutorial) Ciências Biomédicas (Doutoramento) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2014/06/01 - 2014/06/07 Curricular Unit: Molecular toxicology and membrane transport (laboratory tutorial) Genética Humana e Doenças Infecciosas (Doutoramento) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2024 - Current Ibero-American Program of Science and Technology for Development (CYTED) 2024 Program for Thematic Lines
Evaluator
 Ciencia y Tecnología para el Desarrollo, Spain Ciencia y Tecnología para el Desarrollo
2023/12/01 - Current Early Career Researcher Award (ECRA)
Evaluator
 ITQB/IBET Post-Doctoral Association (PDA)
2022/08 - Current Call Innovate Competition 14.0 (AstraZeneca Foundation) - Member Jury A – area Translational Research (iMed Conference® Lisbon 2022)
Evaluator
 Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal AstraZeneca Foundation

Journal scientific committee

Journal title (ISSN) Publisher
2021 - Current Microbiology Spectrum (21650497) American Society of Microbiology
2020 - Current Journal of Genetic Engineering and Biotechnology (2090-5920) Springer Nature
2020 - Current Scientific Reports (2045-2322 ) Nature
2020 - Current Access Microbiology (2516-8290) Microbiology Society
2020 - Current Comparative immunology, microbiology and infectious diseases (0147-9571) Elsevier
2020 - Current Infection, Genetics & Evolution (1567-1348) Elsevier
2019 - Current Journal of Applied Microbiology (1365-2672) Wiley (Blackwell Publishing)
2017 - Current PLoS ONE (1932-6203) Public Library of Science
2019 - 2020 Veterinary Microbiology (0378-1135) Elsevier
2019 - 2019 Frontiers in Microbiology (1664-302X) Frontiers Media SA
2017 - 2019 Journal of Medical Microbiology (1473-5644) Microbiology Society
2018 - 2018 Journal of Antimicrobial Chemotherapy (1460-2091) Oxford University Press
2018 - 2018 Microbial Drug Resistance (1931-8448) Mary Ann Liebert
2017 - 2017 Veterinary Quarterly (1875-5941) Informa UK (Taylor & Francis)
2016 - 2016 Journal of Ethnopharmacology (0378-8741) Elsevier
2016 - 2016 BMC Microbiology (1471-2180) Springer (Biomed Central Ltd.)
2016 - 2016 Phytochemistry Reviews (1572-980X) Springer-Verlag

Mentoring / Tutoring

Topic Student name
2019/03/11 - 2019/03/29 Phytochemical derivatives as efflux pump inhibitors in Staphylococcus aureus Joana Malheiro
2018/10 - 2018/11 Antimicrobial activity of irradiated solutions of antibiotics and non-antibiotics Tatiana Tozar
2015 - 2018 Antimicrobial resistance and molecular characterization of Salmonella enterica spp. isolated from human specimens, food and environmental samples in Luanda, Angola, during 2013-2014 Moisés Francisco
2016/11 - 2017/07 Molecular epidemiology and genetic characterization of Klebsiella pneumoniae isolates from inpatients at The Hospital de Clínicas, UNICAMP Karen Prado Herzer Mattos
2015/02/01 - 2015/07/05 Antimicrobial resistance and molecular characterization of staphylococci collected from inpatients at a Lybian hospital and from ruminants and milk samples Monia Khemiri
2012/09 - 2013/12 Role of plasmid-encoded determinants in antimicrobial resistance of Staphylococcus aureus Cláudia Alexandra Tormenta Palma
2013/05/01 - 2013/05/31 Evaluation of semi-synthetic compounds as efflux inhibitors of MDR efflux systems of Staphylococcus aureus Rolando Cannalire
2012/06/01 - 2012/06/30 Evaluation of tetrahydropyridines as efflux inhibitors of MDR efflux systems of Escherichia coli Andrea von Groll
2010/09 - 2012/01 The contribution of efflux pumps QacA and Smr in multiresistance of Staphylococcus aureus Cláudia Alhinho Mourato
2009/06/01 - 2009/06/21 Membrane transport and efflux Eleni Ntokou

Other jury / evaluation

Activity description Institution / Organization
2023/07/11 - Current Jury member (supervisor) of a Report under the scope of the Curricular Unit "Project in Biochemistry", Lic. in Biochemistry, FCT-NOVA Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021/06/25 - 2021/06/25 Jury member (main arguer) of a Report within the Curricular Unit "Project in Molecular and Cell Biology", Lic. in Molecular and Cell Biology, FCT-NOVA Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Distinctions

Award

2024 Best Short Oral Communication in the Health Microbiology Panel "Galleria mellonella: um modelo in vivo fidedigno para avaliar a eficácia de fármacos para a terapêutica de infeções provocadas por estafilococos."
Sociedade Portuguesa de Microbiologia, Portugal
2024 ISSSI 2024 Travel Award (Awarded to Marcelino Garrine, PhD student (co-supervision))
Australian Society for Microbiology, Australia
2024 Award Professor Doutor Manuel Pinto 2024 (Best Msc student, area Medical Microbiology awarded to MSc student Joana Neves, supervision)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2023 Award Professor Doutor Manuel Pinto 2023 (Best student, area Medical Microbiology awarded to MSc student Marta Leal, co-supervision)
2014 Award Professor Douto Manuel Pinto - Best PhD Thesis in Biomedical Sciences (2013/2014)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2014 Excellence Award Garcia de Orta - Best student (2013/2014)
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Other distinction

2023 Best Poster presentation "Efflux as a resistance mechanism in the veterinary pathogen Staphylococcus pseudintermedius"
6th National Congress of Tropical Medicine (CNMT), Portugal
2013 Post-doctoral Fellowship
Fundação para a Ciência e a Tecnologia, Portugal
2012 Free Registration at 22nd ECCMID
European Society of Clinical Microbiology and Infectious Diseases, Switzerland
2008 Doctoral scholarship
Fundação para a Ciência e a Tecnologia, Portugal