Paulo Jorge Gouveia Simoes Da Silva Oliveira (E41F-4FB7-5948)

Curriculum Vitae

Paulo Jorge Gouveia Simoes Da Silva Oliveira

Paulo J. Oliveira is currently Vice-President and Principal Investigator at the CNC - Center for Neuroscience and Cell Biology, University of Coimbra, Portugal, and Invited Assistant Professor in the same University. He is the current leader of the Mitochondria, Metabolism and Disease group. He received his Bachelor of Science in Biochemistry from the University de Coimbra in 1999. In 2003, he completed his PhD in Cellular Biology from the same University. After obtaining his Ph.D. degree, Paulo Oliveira spent more than three years performing research at the Medical School of the University of Minnesota, Duluth, USA, where he collaborated with several researchers and contributed to the publication of over 20 joint peer-reviewed manuscripts. Paulo Oliveira current research interests focus on mitochondrial biology, investigating the alteration of cardiac mitochondrial function by physical activity and diet, cardiac mitochondrial dysfunction and cell death caused by anti-neoplastic agents, mitochondrial alterations during cancer stem cell differentiation and carcinogenesis or rational designing of mitochondria-directed antioxidants. Paulo has about 300 peer-reviewed publications (h factor ~51, Scopus) and a large number of collaborations in Europe, Africa and in the USA. He has also received several prizes from the Portuguese Cardiology Society for his work on cardiac mitochondrial research, and recently won the FLAD Healthcare 2020 prize. Besides research, Paulo Oliveira is often involved in teaching at the Department of Life Sciences, University of Coimbra, as well as in other Universities in Portugal and elsewhere, besides participating in numerous science communication activities. Of importance, he has maintained a consistent primary role in the organization of national and international scientific meetings, including the International Courses in Toxicology (2005-2010 in Coimbra), Annual Meeting of the European Society for Clinical Investigation (2013, Albufeira, Portugal and 2019, Coimbra, Portugal), the 2014 Meeting of the Portuguese Biochemical Society (Coimbra), and FEBS Advanced Lecture Courses in Oncometabolism (2017, Figueira da Foz, Portugal and 2019 Luso, Portugal).From May 2019 to June 2022, Paulo J. Oliveira was the President of the European Society for Clinical Investigation (www.esci.eu.com), after being its Vice-President for 2 years. Paulo J. Oliveira has also been reviewer for more than 40 different scientific journals and over 10 different national and international funding agencies, including the European Commission (Research Executive Agency) and the Portuguese Foundation for Science and Technology. His research group is supported by competitive national and international funding agencies, including the Portuguese Foundation for Science and Technology, the European Commission, and private foundations. Paulo J. Oliveira is also currently member of the Board of Directors at CNC, as well as member of Board of Directors at CIBB (former CNC.IBILI consortium), the Center for Innovative Biomedicine and Biotechnology. In terms of technology transfer activities, Paulo J. Oliveira is co-inventor in two patents that were licensed to the CNC/University of Porto spin-off company MitoTAG, of which he is one of the co-founders. MitoTAG is a startup that develops targeting systems to deliver antioxidants to mitochondria in order to protect them from the damaging effects of oxidation. This platform technology has applications in diverse areas, namely as active ingredients for anti-aging cosmetics, active principles for the treatment of liver and neurodegenerative diseases, as well as anti-aging food supplements for pets. Finally, Paulo J. Oliveira is also very active in supervising Master (>16 past/present) and Ph.D. students (>30 past/present), as well as Postdocs (14 past/present), being also frequently invited to Master and Ph.D. defenses in Portugal and abroad.

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Identification

Personal identification

Full name: Paulo Jorge Gouveia Simoes Da Silva Oliveira

Citation names

Oliveira, Paulo J.

Author identifiers

Ciência ID: E41F-4FB7-5948
ORCID iD: 0000-0002-5201-9948
Researcher Id: H-1980-2011

Email addresses

pauloliv@cnc.uc.pt (Professional)
pauloliv@ci.uc.pt (Professional)

Telephones

Fax

231249179 (Professional)

Telephone

231249235 (Professional)

Addresses

CNC - Center for Neuroscience and Cell Biology. UC Biotech Building, Lot 8A, Biocant Park, University of Coimbra, 3060-197, Cantanhede, Cantanhede, Portugal (Professional)

Websites

https://cnc.uc.pt/pt/research-group/mitocondria-metabolismo-e-doenca (Professional)

Knowledge fields

Medical and Health Sciences - Basic Medicine - Toxicology
Natural sciences - Biological Sciences - Cell Biology
Medical and Health Sciences - Clinical Medicine - Endocrinology and Metabolism

Languages

Language	Speaking	Reading	Writing	Listening
French	Beginner (A1)	Intermediate (B1)	Beginner (A1)	Beginner (A1)
Spanish; Castilian	Beginner (A1)	Intermediate (B1)	Beginner (A1)	Beginner (A1)
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
Portuguese	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)

Education

	Degree	Classification
2020/10/26 - 2020/10/26 Concluded	Biologia Experimental e Biomedicina (Título de Agregado) Universidade de Coimbra, Portugal
2003 Concluded	Biologia (Doutoramento) Major in Especialidade: Biologia Celular Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Cardiac mithocondrial Function: Studies on the Impact of Disease Conditions and on the Protection Afforded by Carvedilol" (THESIS/DISSERTATION)
1999 Concluded	Bioquimica (Licenciatura) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Efeito do Carvedilol ao Nível da Bioenergética Mitocondrial Cardíaca e da NADH Desidrogenase Externa Mitocondrial de Coração" (THESIS/DISSERTATION)	16

Affiliation

Science

	Category Host institution	Employer
2012/11/01 - Current	Principal Investigator (Research)	CNC.IBILI, Portugal

2006/11/01 - 2012/10/31	Auxiliary Researcher (Research)	CNC.IBILI, Portugal

Teaching in Higher Education

	Category Host institution	Employer
2016 - 2019	Invited Assistant Professor (University Teacher)	Universidade de Coimbra, Portugal

2016 - 2019	Invited Assistant Professor (University Teacher)	Universidade de Coimbra, Portugal

Positions / Appointments

	Category Host institution	Employer
2023/07/01 - Current	Member of the Trustof the Society	ESCI - European Society for Clinical Investigation, Netherlands

2021/05/20 - Current	Coordenador do Programa Doutoral em Biologia Experimental e Biomedicina	Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal

2020/01/01 - Current	Member of Board of Directors	CIBB - Center for Innovative Biomedicine and Biotechnology, Portugal

2020 - Current	Vice-President	Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

2019/01/01 - Current	Member of Board of Directors	CNC.IBILI, Portugal

2019/05/22 - 2022/06/19	President	ESCI - European Society for Clinical Investigation, Netherlands

2016/05/25 - 2019/05/22	Vice-President	ESCI - European Society for Clinical Investigation, Netherlands

Others

	Category Host institution	Employer
2014/02/01 - Current	Leader, "Mitochondria, Metabolism and Disease Group"	CNC.IBILI, Portugal

2006/11/01 - Current	Principal Investigator, "MitoXT: Mitochondrial Pharmacology and Experimental Therapeutics"	CNC.IBILI, Portugal

2013/03/28 - 2016/05/25	Councillor	ESCI - European Society for Clinical Investigation, Netherlands

2013/06/01 - 2015/05/02	Board Member	ESCI - European Society for Clinical Investigation, Netherlands

2006/02/01 - 2011/12/31	Leader "Mitochondrial Pharmacology and Toxicology Group"	CNC.IBILI, Portugal

2003/03/01 - 2011	Adjunct Research Associate	University of Minnesota Medical School - Duluth Campus, United States

2003/03/01 - 2006/10/30	Post-Doc fellow	CNC.IBILI, Portugal

2000/01/01 - 2003/02/01	PhD fellow	Universidade de Coimbra, Portugal

Projects

Contract

	Designation	Funders
2023/03/01 - 2028/08/31	PAS GRAS - De-risking metabolic, environmental and behavioral determinants of obesity in children, adolescents and young adults HORIZON-HLTH-2022-STAYHLTH- 101080329 Universidade de Coimbra, Portugal	European Commission Ongoing
2023/03/01 - 2027/02/28	EXCELScIOR 101087416 Researcher Universidade de Coimbra, Portugal	European Commission Ongoing
2021/01/01 - 2025/12/31	Centro de Inovação em Biomedicina e Biotecnologia - Laboratório Associado LA/P/0058/2020 10.54499/LA/P/0058/2020 Universidade de Coimbra, Portugal Universidade Nova de Lisboa ¿Laboratório de Instrumentação Engenharia Biomédica e Física da Radiação, Portugal Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2022/01/15 - 2025/01/14	Células Neuronais Humanas Diferenciadas a partir de Células Estaminais Derivadas de Urina como Plataforma para a Medicina Personalizada na Esclerose Lateral Amiotrófica PTDC/BTM-ORG/0055/2021 Universidade de Coimbra, Portugal CNC.IBILI, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2019/01/01 - 2024/12/31	Lifelong exercise: modulating immunometabolic pathways for decreasing cancer risk. 10/22 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal Universidade de Coimbra Unidade de Investigação e Desenvolvimento Química-Física Molecular, Portugal Universidade de Coimbra Centro de Investigação do Desporto e da Actividade Física, Portugal Unidade Local de Saúde de Coimbra EPE, Portugal	Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia Ongoing
2023/03/10 - 2024/09/09	Desferrização da ataxia de Friedreich com quelantes inovadores direcionados para a mitocôndria 2022.04633.PTDC Universidade do Porto Faculdade de Ciências, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2023/03/01 - 2024/08/31	Novas abordagens terapêuticas para a obesidade baseadas na sinalização dopaminérgica periférica 2022.05822.PTDC Universidade de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2023 - 2024	Profiling the Impact of Physical Activity Using Infra-Red Spectroscopy and Machine Learning Non-Invasive Sampling n.a. Principal investigator Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal	Fundación Mapfre Ongoing
2021/01/01 - 2023/12/31	Organelle-targeted Radiocomplexes for Auger Therapy of Cancer PTDC/MED-QUI/1554/2020 Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal Centro de Ciências e Tecnologias Nucleares, Portugal Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2022/01/01 - 2023/06/30	Função da homeostasia tiol-mitocondrial na neurodegeneração: implicações para a esclerose lateral amiotrófica EXPL/BTM-TEC/1407/2021 Universidade de Coimbra, Portugal CNC.IBILI, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2022/01/01 - 2023/06/30	Mitocôndria como potencial mediador do dimorfismo sexual nas alterações pato-morfológicas da microglia e ansiedade causadas pelo stress pré-natal<br> EXPL/MED-NEU/1002/2021 Universidade de Coimbra, Portugal CNC.IBILI, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2020/07/01 - 2023/06/30	Preservação do património natural e cultural e validação científica das práticas com plantas medicinais do Vale do Côa COA/BRB/0019/2019 Universidade de Coimbra, Portugal CNC.IBILI, Portugal Instituto Politécnico de Bragança, Portugal Universidade de Aveiro, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2022/06/01 - 2023/05/31	Proof of Concept “MitoBOOST v2.0 - A Proof of Concept for the Use of Mitochondria-Targeted Polyphenols to Treat Non-Alcoholic Fatty Liver Disease 181226 Principal investigator CIBB - Center for Innovative Biomedicine and Biotechnology, Portugal	Agência para a Competitividade e Inovação IP Ongoing
2018/06/01 - 2022/02/28	Eficácia pré-clínica do sulforafano ou do extrato total de Brássicas: uma estratégia para combater a obesidade e valorizar os subprodutos de Brássicas PTDC/ASP-HOR/29152/2017 Universidade de Trás-os-Montes e Alto Douro, Portugal Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2018/06/01 - 2022/01/31	O papel do metabolismo extra-hepático da frutose no desenvolvimento de doença hepática gordurosa não alcoólica PTDC/BIA-BQM/28147/2017 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal Universidade de Aveiro, Portugal Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2018/07/26 - 2021/07/25	Uso de fitoquímicos redox-activos para desencadear a hormesis mitocondrial: Desenvolvimento de uma nova geração de ingredientes para a cosmética PTDC/BIA-MOL/28607/2017 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal Universidade do Porto, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2021 - 2021	Summer with Science: Research, Development and Interdisciplinary Innovation in the Physiolopathology of Aging and Lifestyle-dependent Diseases n.a. Principal investigator CIBB - Center for Innovative Biomedicine and Biotechnology, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2018 - 2021	MitoSHIELD - Redox-active Phytochemicals Triggering Mitochondrial Hormesis: Developing a New Generation of Cosmetic Active Ingredients PTDC/BTM-SAL/29297/2017 Principal investigator Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2018 - 2021	The Role of Visceral Fructose Metabolism in the Development of Non-alcoholic Fatty Liver Disease 02/SAICT/2017/028147 Researcher Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2018 - 2021	Development and validation of innovative screening methods for mitochondrial health modulators PTDC/BTM-SAL/29297/2017 Researcher Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2018 - 2021	MitoCIN- Hydroxycinnamic derivatives, methods and uses thereof, Intelectual Protection Support Portugal2020/call 17/SI/2015/37586 Principal investigator	Ongoing
2018 - 2021	Development of mitochondriotropic antioxidants based on a hydroxybenzoic acid scaffold, Intelectual Protection Support Portugal2020/call 04/SAICT/2017/037892 Principal investigator	Ongoing
2018 - 2021	VALORIZEBYPRODUCTS: Preclinical efficacy of sulforaphane or Brassica whole extract: a strategy to fight obesity and valorize Brassica byproducts POCI-01-0145-FEDER-029152 POCI-01-0145-FEDER-029152 Researcher Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal Universidade de Trás-os-Montes e Alto Douro, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2018 - 2021	Mito4ALS: Development of Novel Mitochondria-Targeted Antioxidants for Improving SOD1-Familial Amyotrophic Lateral Sclerosis Phenotype PTDC/MED-FAR/29391/2017 PTDC/MED-FAR/29391/2017 Researcher Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2017/07 - 2020/06	mitoFOIE GRAS: Non-invasive Profiling of Mitochondrial Function in Non-Alcoholic Fatty Liver Disease 734719 Principal investigator	European Commission Ongoing
2020 - 2020	Summer Course: Methodologies for Scientific Research – Interdisciplinary Research, Development and Innovation in Cell and Molecular Metabolism 15-20/7/245 Principal investigator CIBB - Center for Innovative Biomedicine and Biotechnology, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2019/01/01 - 2019/12/31	CNC. IBILI UID/NEU/04539/2019 Universidade de Coimbra, Portugal Universidade Nova de Lisboa ¿Laboratório de Instrumentação Engenharia Biomédica e Física da Radiação, Portugal Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2017/01 - 2019/12	FOIE GRAS - Bioenergetic Remodeling in the Pathophysiology and Treatment of Non-Alcoholic Fatty Liver Disease 722619 Principal investigator	European Commission Ongoing
2016/04/01 - 2019/09/30	EXERCITANDO O FUTURO: Exercício Voluntário Durante Diabetes Gestacional com uma Estratégia para Melhorar a Função Mitocondrial na Descendência PTDC/DTP-DES/1082/2014 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal Universidade do Porto Faculdade de Desporto, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2016/04/01 - 2019/09/30	MitoBOOST: Uma Terapeutica de Nova Geração para a Doença de Fígado Gordo Não Alcoólico Baseado na Entrega Inteligente de Antioxidantes à Mitocôndria PTDC/DTP-FTO/2433/2014 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal Universidade do Porto Faculdade de Ciências, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2017 - 2019	Tackling CANcer STEM CELls: A Challenge and an Opportunity to Advance in Anti-cancer Therapy SAICTPAC/0022/2015 SAICTPAC/0022/2015 Researcher	Fundação para a Ciência e a Tecnologia Ongoing
2016 - 2019	Exercising obesity - The Role of Exercise Against Endoplasmic Reticulum Stress in Obesity-induced Liver Disease PTDC/DTP-DES/7087/2014 PTDC/DTP-DES/7087/2014 Researcher	Fundação para a Ciência e a Tecnologia Concluded
2015/10 - 2018/09	EXERCISING THE FUTURE: Voluntary Exercise During Gestational Diabetes as a Means to Improve Mitochondrial Function in the Offspring grant.Provided by PTCRIS: 139707 Researcher CNC.IBILI, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2015/10 - 2018/09	MitoBOOST: A Next-Generation Therapeutics for Non-Alcoholic Fatty Liver Disease Based on Smart Antioxidant Delivery to Mitochondria grant.Provided by PTCRIS: 141059 Principal investigator	Fundação para a Ciência e a Tecnologia Concluded
2018 - 2018	Mitochondrial-derived Peptides in Cell Homeostasis FLAD Healthcare 2020 Principal investigator Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação Luso-Americana Concluded
2015 - 2018	FishFree: A Contribution to the Validation of an Alternative Assay for Fish Lethal Ttesting PTDC/AAG-TEC/4966/2014 PTDC/AAG-TEC/4966/2014 Researcher Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2014 - 2016	An Epigenetic Engineering Approach to Reverse the Parkinson Disease (PD) Cell State (co-investigator) n.a. Principal investigator	Montepio Geral - private Bank Concluded
2014 - 2015	Hypercholesterolemia as a risk factor for Alzheimer’s Disease: impact on nitric oxide bioavailability and bioactivity 8. Transnational Cooperation Agreement Project, CAPES/FCT 2013 Researcher Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2013 - 2015	Pathophysiology of Persistent Doxorubicin Cardiotoxicity: a Mitochondrial-Epigenetics Link PTDC/DTP-FTO/1180/2012 PTDC/DTP-FTO/1180/2012 Principal investigator	Foundation for Science and Technology - Portugal Concluded
2011/03/01 - 2014/08/31	Actividade Protectora da SIRT3 na Disfunção Mitocondrial Induzida por Fármacos PTDC/SAU-TOX/110952/2009 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2011 - 2014	Protective Activity of SIRT3 Against Drug-induced Mitochondrial Dysfunction PTDC/SAU-TOX/110952/2009 PTDC/SAU-TOX/110952/2009 Principal investigator Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Foundation for Science and Technology - Portugal Concluded
2010/05/01 - 2013/10/30	Clarificação do Papel Mitocondrial na Cardiotoxicidade da Doxorubicina Usando um Sistema de Perfusão de Corações Intactos - Papel de Diferentes Calendários de Tratamento com Doxorubicina PTDC/SAU-OSM/104731/2008 PTDC/SAU-OSM/104731/2008 Researcher Instituto do Mar, Portugal University of Minnesota Twin Cities School of Medicine Duluth Campus, United States Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Fundação para a Ciência e a Tecnologia Concluded
2010/04/01 - 2013/03/31	A Abertura da Caixa de Pandora Para uma Terapia Activa Anti-cancro da Mama - O Papel do Direccionamento Selectivo da Mitocôndria PTDC/QUI-QUI/101409/2008 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal Mercer University School of Medicine, United States University of Minnesota Medical School - Duluth Campus, United States Universidade de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010/04 - 2013/03	Opening Pandora's Box for Active Anti-Breast Cancer Therapy - The Role of Selective Targeting to Mitochondria 101409 Principal investigator Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluded
2010 - 2013	Role of Mitochondrial Physiology in Tumor Stem Cell Resistance to Chemotherapeutics PTDC/QUI-BIQ/101052/2008 Principal investigator Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Foundation for Science and Technology - Portugal Concluded
2010 - 2013	Metabolism as a Modulator of Stem Cell Pluripotency and Differentiation PTDC/EBB-EBI/101114/2008 PTDC/EBB-EBI/101114/2008 Researcher Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Foundation for Science and Technology - Lisbon Concluded
2010 - 2013	Can Phytoestrogens be Safe and Effective Food Additives for Women During Menopause? - An In Vitro and In Vivo Approach to the problem PTDC/AGR-ALI/108326/2008 PTDC/AGR-ALI/108326/2008 Researcher Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Foundation for Science and Technology - Portugal Concluded
2010 - 2013	Role of Mitochondrial Physiology in Tumor Stem Cell Resistance to Chemotherapeutics PTDC/QUI-BIQ/101052/2008	Foundation for Science and Technology - Portugal
2011/01/01 - 2012/12/31	Strategic Project - LA 1 - 2011-2012 PEst-C/SAU/LA0001/2011 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010 - 2012	MitocancerStem ¿ Role of Mitochondrial Physiology in Tumor Cell Resistance to Chemotherapeutics FP7-People-2009-IEF 251850	European Commission
2009 - 2011	Anticancer Activity of Novel Polyamine Pd(II) Complexes - A Multidisciplinary Study PTDC/QUI/66701/2006 PTDC/QUI/66701/2006 Researcher	Foundation for Science and Technology - Portugal Concluded
2007/09/15 - 2010/03/13	Novos Mecanismos Mitocondriais Para a Toxicidade Cardioselectiva da Doxorubicina PTDC/SAU-OSM/64084/2006 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal Universidade do Porto Centro de Investigação em Actividade Física Saúde e Lazer, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2007/09/15 - 2010/03/13	Novel Mitochondrial Mechanisms for the Cardioselective Toxicity of Doxorubicin PTDC/SAU-OSM/64084/2006 Universidade do Porto Centro de Investigação em Actividade Física Saúde e Lazer, Portugal Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2007 - 2009	Influence of Cell Differentiation State on Apoptosis Induced by Isoproterenol on Embryonic Ventricular H9c2 Cells - Signalling Pathways Involved PTDC/QUI/64358/2006 PTDC/QUI/64358/2006 Researcher	Foundation for Science and Technology - Portugal Concluded
2005/07/01 - 2008/09/30	Influência das Soluções de Preservação para Transplante nos Perfis Metabólico e Imunológico Cardíacos POCI/SAU-OBS/55802/2004 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2005 - 2008	Development of Novel Anticancer Agents: Phenolic Derivatives of Natural and Synthetic Origin - Structure-Activity Relationships POCTI/QUI/55631/2004 Researcher	Foundation for Science and Technology - Portugal Concluded
2005/10/15 - 2007/04/15	Desenvolvimento de Novos Agentes Anticancerígenos: Derivados Fenólicos de Origem Natural ou Sintética - Relações Estrutura-Actividade POCI/QUI/55631/2004 Universidade de Coimbra, Portugal Universidade de Coimbra Unidade de Investigação e Desenvolvimento Química-Física Molecular, Portugal Universidade do Porto Faculdade de Farmácia, Portugal Instituto Politécnico do Porto Instituto Superior de Engenharia do Porto, Portugal Universidade do Porto Faculdade de Ciências, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2003/02/15 - 2006/10/14	ADRIAMYCIN - ASSOCIATED CARDIOMYOPATHIES - IMPACT OF METABOLIC THRESHOLDS IN SELECTIVE ORGAN TOXICITY AND DIFFERENTIAL ACTIVATION OF MITOCHONDRIAL ATP-SENSITIVE POTASSIUM CHANNELS SFRH/BPD/8359/2002	Fundação para a Ciência e a Tecnologia Concluded
2000/01/01 - 2003/01/31	UTILIZAÇÃO SISTEMÁTICA DE CARDIOMIÓCITOS E DE MITOCÔNDRIAS CARDÍACAS ISOLADAS COMO MODELO DE AVALIAÇÃO FARMACOLÓGICA E TOXICOLÓGICA DE FÁRMACOS COM ACÇÃO A NÍVEL CARDÍACO PRAXIS XXI/BD/21494/99	Fundação para a Ciência e a Tecnologia Concluded
2000 - 2003	Mitochondria and diabetes: mitochondrial function in the brain and heart of non-insulin dependent animal models (Goto-Kakizaki) POCTI/ESP/43642/1999 POCTI/ESP/43642/1999 Researcher Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal	Fundação para a Ciência e a Tecnologia Fundação para a Ciência e a Tecnologia Concluded

Other

	Designation	Funders
2022/01/15 - 2025/01/14	Human Neuronal Cells Differentiated from Urine-derived Stem Cells as a Platform for Personalized Medicine in Amyotrophic Lateral Sclerosis PTDC/BTM-ORG/0055/2021 Universidade de Coimbra, Portugal Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia Ongoing

Outputs

Publications

Book chapter	Gonçalo J.M. Afonso; Rui F. Simões; Sonia L.C. Pinho; Paulo J. Oliveira; Teresa Cunha-Oliveira. "Challenges in mitochondrial profiling during pre-clinical studies". 2023. 10.1016/B978-0-323-88462-4.00002-X Duarte, Ana I.; Sadowska-Bartosz, Izabela; Karkucinska-Wieckowska, Agnieszka; Lebiedzinska-Arciszewska, Magdalena; Palmeira, Carlos M.; Rolo, Anabela P.; Kabiri, Yaschar; et al. "A metabolic and mitochondrial angle on aging". In Aging, edited by Oliveira PJ; Malva JO, 175-256. Elsevier, 2023. Published • 10.1016/b978-0-12-823761-8.00024-0 Cagide, Fernando; Oliveira, Catarina; Teixeira, José; Oliveira, Paulo J.; Borges, Fernanda. "Bridging the Gap Between Nature and Antioxidant Setbacks: Delivering Gallic Acid to Mitochondria". In Methods in Molecular Biology, 161-172. Springer US, 2021. 10.1007/978-1-0716-1262-0_10 Ferreira, Luciana L.; Oliveira, Paulo J.; # Cunha-Oliveira, Teresa. Corresponding author: # Cunha-Oliveira, Teresa. "Epigenetics in Doxorubicin Cardiotoxicity". In Pharmacoepigenetics, edited by Cacabelos, Ramón, 837-846. Elsevier, 2019. Published • 10.1016/b978-0-12-813939-4.00033-4 Simões, Rui F.; Cunha-Oliveira, Teresa; Costa, Cláudio F.; Sardão, Vilma; Oliveira, Paulo. "In Vitro Methodologies to Investigate Drug-Induced Toxicities". In Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants, 229-247. John Wiley & Sons, Inc., 2018. Published • 10.1002/9781119329725.ch14 Silva, Filomena S. G.; Costa, Cláudio F.; Marques, Ricardo J.; Oliveira, Paulo J.; Pereira, Gonçalo C.. "Pharmacological Targeting of the Mitochondrial Permeability Transition Pore for Cardioprotection". In Mitochondrial Biology and Experimental Therapeutics, edited by Oliveira, Paulo J., 423-490. NewYork: Springer International Publishing, 2018. Published • 10.1007/978-3-319-73344-9_20 Deus, Cláudia; Branco, Ana F.; Oliveira, Paulo J.; Sardão, Vilma. "Caffeine Cardiovascular Toxicity". In Coffee in Health and Disease Prevention, 699-707. Elsevier, 2015. 10.1016/b978-0-12-409517-5.00078-4 Marques-Aleixo, Inês; Santos-Alves, Estela; Moreira, Paula I.; Oliveira, Paulo J.; Magalhães, José; Ascensão, António; Marques-Aleixo, I.; et al. "Exercise-Induced Protection Against Aging and Neurodegenerative Diseases". In Diet and Exercise in Cognitive Function and Neurological Diseases, 309-321. John Wiley & Sons, Inc, 2015. 10.1002/9781118840634.ch26 Moreira, Ana; Machado, Nuno; Bernardo, Telma; Sardao, Vilma; Oliveira, Paulo J.. "Mitochondria as a Biosensor for Drug-induced Toxicity ¿ Is It Really Relevant?". In Biosensors for Health, Environment and Biosecurity. InTech, 2011. Published • 10.5772/17805
Conference abstract	Marques, M. Pedro; Landim, Euclides; Varela, Carla; MARQUES, JOANA; da Costa, Ricardo MF; Carvalho, Aida; Oliveira, Paulo J.; Cabral, Célia. "Valorization of the neglected species Verbascum pulverulentum Vill. from Côa Valley for possible cosmetic applications". Paper presented in III Bio.Natural 2023 - Bioactive Natural Products Research Conference, Lisbon, 2023. Accepted Sousa, Diana; Amaro, A; Ferreira Junior, Marcos Divino; Susana P. Pereira; Rocha, Mariana; Barra, Cátia; Mello-Gomes, Rodrigo; Oliveira, Paulo; Matafome, Paulo. "Exposure to obesogenic environments during perinatal development modulates offspring nutrient sensing pathways in adipose tissue.". Paper presented in 56th Annual Scientific Meeting of the European Society for Clinical Investigation, Bari, 2022. Published Melim, Catarina; Teixeira, José; Varela, Carla; Marques, Mário; Sardão, Vilma; Oliveira, Paulo; Célia Cabral. "Potential of Côa Valley (Portugal) Plants Extracts in Cell Model for Hepatic Lipid Toxicity". Paper presented in 56th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI), Bari, 2022. Published Teixeira Camila; Marques CC; Baptista MC; Pimenta, J.; Teixeira, José; Cagide F; Borges, F; et al. "Effect of a new mitochondriotropic antioxidant on oocyte maturation and embryo production". Paper presented in 71st Annual Meeting of European Federation of Animal Science (EAAP), Porto, 2020. Published Teixeira Camila; Marques CC; Baptista MC; Pimenta, J.; Teixeira J; Cagide F; Borges F; et al. "Beneficial effect of mitochondriotropic antioxidants on oocyte maturation and embryo production". Paper presented in 54th Annual Scientific Meeting European Society for Clinical Investigation (ESCI) Bridging Gaps in Aging, Translational, and Transitional Research, Bari, 2020. Published • 10.1111/eci.13109 Diniz, Mariana S.; Grilo, Luís F.; João D. Martins; Stephen Ford; Peter W. Nathanielsz; Oliveira, Paulo J.; Susana P. Pereira. "Maternal obesity (MO) during pregnancy: are there implications for maternal hepatic mitochondrial activity?". Paper presented in ESCI Virtual Meeting 2020, 2020. 10.1111/eci.13369 Marques, R; Oliveira, Paulo; Oliveira GL. "ANT2 Silencing Promotes a Metabolic Shift in P19 Embryonal Carcinoma Stem Cells". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI), Coimbra, 2019. https://doi.org/10.1111/eci.13127 Marques, R; Silva MR; Oliveira, Paulo. "P-cadherin effect in mitochondrial dynamics and biogenesis of breast cancer cells". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI), Coimbra, 2019. 10.1111/eci.13127 Ana M Silva; Videira, Romeu; Moreira, Ana C.; Oliveira, Paulo; Carvalho, RA; Carvalho, R; Carvalho Rui; Sardão, Vilma. "Delving the Bone-buried Osteocytes lipid metabolism commitment in post-menopausal osteoporosis.". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation, Coimbra, 2019. Santos-Alves, Estela; Marques-Aleixo, Inês; Coxito, Pedro; Balça, Maria Manuel; Rizo-Roca, David; Torrella, J. Ramon; Oliveira, Paulo J.; et al. "Doxorubicin and physical exercise modulate hepatic mitochondrial bioenergetics, oxidative stress, apoptotic signaling, dynamics and quality control". Paper presented in 48th annual scientific meeting of the European Society for Clinical Investigation. European Journal of Clinical Investigation., Utrecht, 2014. Published Monteiro, João P.; Ana M Silva; Jurado, Amália S.; Oliveira, Paulo. "Rapeseed oil-rich diet impacts hepatic mitochondrial physiology and in vitro menadione and nimesulide toxicity". Paper presented in 47th Annual Meeting of the European Society of Clinical Investigation, Albufeira, 2013. Gonçalves IO; Emanuel Passos; Rocha-Rodrigues, Sílvia; Cátia V. Diogo; Santos-Alves, Estela; Oliveira, Paulo J.; António Ascensão; José Magalhães. "The preventive role of voluntary physical activity against high-fat diet induced liver mitochondrial dysfunction". Paper presented in Eur J Clin Invest, Albufeira, 2013. Published Gonçalves IO; Emanuel Passos; Rocha-Rodrigues, Sílvia; Cátia V Diogo; Estela Santos-Alves; Oliveira, Paulo J.; António Ascensão; José Magalhães. "Modulation of liver mitochondrial bioenergetics and apoptotic signaling by endurance training in high-fat diet fed rats". Paper presented in Eur J Clin Invest, Albufeira, 2013. Published Gonçalves IO; Emanuel Passos; Rocha-Rodrigues, Sílvia; Cátia V. Diogo; Santos-Alves, Estela; Oliveira, Paulo J.; Ascensão, António; Magalhães, J.. "Preventive and Therapeutic effects of physical exercise against obesity: study of clinical and anthropometric variables in rats fed with hipercaloric diets". Paper presented in 47th Annual Scientific Meeting of the European Society for Clinical Investigation, Albufeira, 2013. António Ascensão; Gonçalves IO; Lumini-Oliveira, José; Marques-Aleixo, Inês; Emanuel Passos; Rocha-Rodrigues, Silvia; Nuno Machado; et al. "Modulation of liver mitochondrial bioenergetics by endurance training and chronic intermittent hypobaric hypoxia. Relevance for salicylate-induced mitochondrial dysfunction". Paper presented in Eur J Clin Invest, Budapeste, 2012. Published Ascensão, António; Gonçalves IO; Lumini-Oliveira, José; Marques-Aleixo, Inês; Emanuel Passos; Rocha-Rodrigues, Sílvia; Nuno Machado; et al. "Endurance Training and Chronic Intermittent Hypobaric-Hypoxia Modulate Liver Mitochondrial Bioenergetics. Role Against Salicylate-Induced Mitochondrial Dysfunction". Paper presented in Med Sci Sports Exerc, 2012. Mota, Paula C.; Tavares, Renata S.; Cordeiro, M.; Pereira, Susana P.; Oliveira, Paulo J.; Ramalho-Santos, João. "Acute effects of TCDD administration on spermatogenesis and sperm: special emphasis on mitochondrial function". Stockholm, 2012. Published Moreira, Ana C.; Ana M Silva; Oliveira, Paulo; Santos, Maria Sancha; Holy, John; Sardão, Vilma. "Estrogen Dependent Effects on Breast Cancer Cell Motility and Proliferation". Paper presented in XLI Annual Meeting of the Portuguese Society of Pharmacology, Coimbra, 2011. Martins, Fatima; Margarida, Ana; Oliveira, Maria M.; Oliveira, Paulo J.; Francisco Peixoto. "Toxicity of parabens in testis mitochondria; a possible role on male infertility". 2011. Published • 10.1016/j.bbabio.2008.05.239 Diogo, C. V.; Félix, L.; Vilela, S.; Burgeiro, A.; Barbosa, I.A.; Carvalho, M.J.M.; Oliveira, Paulo J.; et al. "Possible anti-cancer application of the phytochemicals daphnetoxin and daphnoretin-relevance of mitochondrial toxicity". Paper presented in 44th Annual Scientific Meeting of the European Society for Clinical Investigation, Bari, 2010. Published Alves, Marco G.; Martins, Fátima O.; Oliveira, Paulo J.; Carvalho, Rui A.. "Energy metabolism assessment during heart preservation in celsior and histidine buffer solution by 1H-NMR spectroscopy". Paper presented in 34th Federation of european Bichemical societies (FEBS) congress, Praga, 2009. Published
Conference paper	Marques, Mário Pedro; Landim, Euclides; Varela, Carla; Marques, Joana; Costa, Ricardo M.F. da; Carvalho, Luís A.E. Batista de; Carvalho, Aida; Oliveira, Paulo J.; Cabral, Célia. "Côa Valley’s medicinal plants as potential cosmetic ingredients: cytotoxic and antioxidant assessment". 2023. Miranda-Santos, I.; Pereira, Carolina; Pinho, Sónia Andreia; Oliveira, Paulo J.; Cunha-Oliveira, T.. "Visualization of metabolic rewiring of NHDF cells in response to extracellular glucose concentration". Paper presented in 55th Annual Meeting of the European Society for Clinical Investigation, 2021. Published Cunha-Oliveira, T.; Carvalho, M.; Sardão, V.; Oliveira, Paulo J.; Silva, Filomena S.G.. "Multi-dimensional Analysis of Metabolic and Mitochondrial Dysfunction Parameters in Lymphoblasts from Amyotrophic Lateral Sclerosis Patients". Paper presented in 55th Annual Meeting of the European Society for Clinical Investigation, 2021. Published Afonso, Gonçalo; Inês Miranda-Santos; Carvalho, RA; Carvalho, R; Carvalho Rui; Oliveira, Paulo J.; Cunha-Oliveira, T.. "Impact of Rebaudioside A in the metabolism of breast cancer cells and assessment of its chemotherapeutic potential". Paper presented in ESCI Virtual Meeting 2020 ¿ COVID19 edition, 2020. Published Pino, Rute; Cunha-Oliveira, T.; Carvalho, Filipa S; Garcia, Rita; Burgeiro, Ana; Lourenço, Nuno; Carvalho, RA; Carvalho, R; Carvalho Rui; Oliveira, Paulo J.. "A Data Science Approach to Sub-chronic Doxorubicin Cardiotoxicity Reveals Hidden Patterns of Metabolic Remodeling". Paper presented in ESCI Virtual Meeting 2020 - COVID19 edition, 2020. Published Coelho, Ana R; J. Kovarova; M. Bajzikova; J. Rohlena; Oliveira, Paulo J.; Jiri Neuzil. "Mitochondrial dihydroorotate dehydrogenase plays an important role in tumor formation". Paper presented in 53rd Annual Scientific Meeting of the European Society for Clinical Investigation, Coimbra, 2019. Tavares, Rui; Ramalho-Santos, João; Oliveira, Paulo J.; Azul, Anabela Marisa. "Using Comics to Bring Mitochondria to ¿Real-Life¿". Paper presented in 6th International Conference for Illustration and Animation, Esposende*, 2018. Published Ferreira, Fernanda M.; Pereira, Olívia R.; Cardoso, Susana M.; Oliveira, Paulo J.; Moreno, António J.M.. "Potential noxious effect of mentha aquatica L. on mitochondrial bioenergetics". 2015.
Conference poster	Marques, Mário P.; Euclides Landim; Joana Marques; da Costa, Ricardo MF; Luis Baptista de Carvalho; Dias, Maria Inês; Barros, Lillian; et al. "Cistus Species from Côa Valley: a Source of Antioxidants for Natural-based Cosmetics". Paper presented in Mitochondria in Aging, Cancer and Cell Death (MAC), 2023. Amorim, Ricardo; Melim, Catarina; Marques, Mário P.; Varela, Carla; Dias, Maria Inês; Barros, Lillian; Teixeira, José; Oliveira, Paulo; Célia Cabral. "Protective Effects of Equisetum ramosissimum Desf. Against Palmitic Acid-induced Lipid Accumulation and Mitochondrial Dysfunction in Human HepG2 Cells". Paper presented in 57th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI), 2023. Benfeito, Sofia; Fernandes, Carlos; Chavarria, Daniel; Barreiro, Sandra; Cagide, Fernando; Silva, Catia; Teixeira, José; et al. "Synthesis and in vitro evaluation of versatile cell-penetrating mitochondriotropic antioxidants". Paper presented in XXVI Encontro Galego-Portugués de Química, 2022. Chavarria, Daniel; Benfeito, Sofia; Garrido, Jorge; Serrão, Paula; Soares-da-Silva, Patrício; Remião, Fernando; Oliveira, Paulo; Borges, Fernanda. "Tackling dopamine depletion and oxidative stress with innovative caffeic acid derivatives". Paper presented in X Meeting of the Paul Ehrlich Euro-PhD Network, 2022. Ilina, V.; Teixeira, José; Varela, Carla; Marques, Mário; Sardão, Vilma; Melim, Catarina; Baranenko, D.; Oliveira, Paulo; Cabral, Célia. "In Vitro Cardioprotective Potential of Côa Valley (Portugal) Plants Extracts Against Lipotoxic Insults". Paper presented in 56th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI), 2022. Mena, Débora; Pedro Soares; Cagide, Fernando; Benfeito, Ester; Grilo, Luís F.; Daniela F. Silva; Valente, Pedro; et al. "The Mitochondria-Targeted Antioxidant Antioxcin4 Protects Against Oxidative/Nitrosative Stress in the Amyotrophic Lateral Sclerosis SOD1GG3A Mouse". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience, 2021. Salermo, A.; Albertini, C.; Atzeni, S.; Uliassi, F.S.G.; Massenzio, F.; Monti, B.; Chavarria, Daniel; et al. "Combining riluzole/dexpramipexole and rasagiline in new multi-target-directed ligands in the context of Amyotrophic Lateral Sclerosis". Paper presented in 13th Young Medicinal Chemist Virtual Symposium, 2021. Simões, Rui F.; Cunha-Oliveira, Teresa; Oliveira, Paulo; Pereira, Francisco. "Differentiated SH-SY5Y cells as a cellular model to study mitochondrial physiology and dynamics". Paper presented in 54th Annual Scientific Meeting of the European Society for Clinical Investigation, COVID Edition, 2020. Marques, R; Serafim, Teresa; Deus CM; Silva, F.S.G.; Sardão, Vilma; Dias, Sérgio; Oliveira, Paulo. "Glucose dependence and metabolic reprogramming of commercial breast cancer cells.". Paper presented in EACR-AACR-ASPIC Conference on Tumor Microenvironment, 2020. Silva FSG; Cunha-Oliveira T; Silva, D.F; Daniela Silva; Daniela F. Silva; Luis Segura; Ricardo Marques; Tatiana Rosenstock; Oliveira, Paulo. "Oxidant/antioxidant imbalance in lymphoblast from amyotrophic lateral sclerosis patients with SOD1 mutations and unknown mutations". Paper presented in 11th World Congress on Targeting Mitochondria, 2020. Pino, Rute; Cunha-Oliveira, T.; Carvalho, Filipa S.; Garcia, Rita; Burgeiro, Ana; Carvalho, Rui; Oliveira, Paulo J.; Lourenço, Nuno. "Unraveling metabolic effects underlying acute cardiotoxicity of the antineoplastic drug Doxorubicin". Paper presented in FEBS 2019 Advanced Course. Oncometabolism: From Conceptual Knowledge to Clinical Applications, Luso, Portugal, 2019. Silva, Filomena S.G.; Cunha-Oliveira, T.; Bento, Guida; Oliveira, Paulo J.. "Data mining analysis of respiratory and glycolytic fluxes from amyotrophic lateral sclerosis patients: Unraveling the effect of SOD1 mutation.". Paper presented in FEBS 2019 Advanced Course. Oncometabolism: From Conceptual Knowledge to Clinical Applications, Luso, Portugal, 2019. Marques, R; Carvalho, M; Borges D; Oliveira, Paulo; Silva FSG. "Alterations in mitochondrial biogenesis and regulation of morphology in lymphoblasts from amyotrophic lateral sclerosis patients.". Paper presented in 2nd FEBS 2019 Advanced Course on. Oncometabolism: From Conceptual Knowledge to Clinical Applications, 2019. Marques, R; Borges D; Carvalho, M; Oliveira, Paulo; Silva FSG. "Understanding the influence of SOD1 mutation on mitochondrial mechanisms of autophagy and apoptosis in lymphoblasts from amyotrophic lateral sclerosis patients". Paper presented in 2nd FEBS 2019 Advanced Course on. Oncometabolism: From Conceptual Knowledge to Clinical Applications, 2019. Marques, R; Sousa, Bárbara; Sardão, Vilma; Schmitt, F.; Oliveira, Paulo; Paredes, Joana. "P-cadherin induces anoikis resistance in breast cancer stem cells by rewiring the metabolic flux and activating of antioxidant systems". Paper presented in 2nd FEBS 2019 Advanced Course on. Oncometabolism: From Conceptual Knowledge to Clinical Applications, 2019. Marques, R; Oliveira, G.; Oliveira, Paulo. "Adenine Nucleotide Translocase 2 silencing induces metabolic remodelling in P19 embryonal carcinoma stem cells". Paper presented in . 2nd FEBS 2019 Advanced Course on. Oncometabolism: From Conceptual Knowledge to Clinical Applications, 2019. Marques, R; Deus C; Silva, F.S.G.; Sardão, Vilma; Oliveira, Paulo; Serafim, Teresa. "Metabolic reprogramming forwards oxidative phosphorylation in breast cancer cells as potential drug targets". Paper presented in 2nd FEBS 2019 Advanced Course on Oncometabolism: From Conceptual Knowledge to Clinical Applications, 2019. Simões, Rui F.; Cunha-Oliveira, Teresa; Oliveira, Paulo; Pereira, Francisco. "Early mitochondrial metabolism and dynamics changes as predictors of neurodegeneration and neuronal cell death". Paper presented in 53rd Annual Scientific Meeting of European Society for Clinical Investigation, 2019. Bento, Guida; Oliveira, Paulo; Macedo, Maria; Sardão, Vilma. "Human urine-derived cells from young and old donors for assessing glycolytic and oxidative phosphorylation functions.". Paper presented in MitoPorto ¿ Mitochondrial evolution, metabolism and diseases, International symposium, University of Porto, Portugal,, 2018. Simões, Rui F.; Cunha-Oliveira, Teresa; Oliveira, Paulo; Pereira, Francisco. "Dose-dependent analysis of mitochondrial parameters in differentiated SH-SY5Y cells exposed to mitochondrial toxicants". Paper presented in 2nd Edition MitoPorto, 2018. Fonseca, Ana Catarina; Burgeiro, Ana; Dias, Cândida; Baldeiras, Inês; Cunha-Oliveira, Teresa; Lourenço, Nuno; Costa-Nunes, João; et al. "Mitochondrial function and oxidative stress in diabetic and non-diabetic human epicardial versus subcutaneous adipose tissue.". Paper presented in Mitoporto, Mitochondrial evolution, metabolism and disease,, 2018. Marques, R; Sousa, B.; Pereira, J.; Nobre AR; Carneiro P,; Sardão, Vilma; Schmitt, F.; Oliveira, Paulo; Paredes, Joana. "P- Cadherin promotes anoikis resistance in breast cancer stem cells by stimulating the glycolytic behavior and lowering the oxidative". Paper presented in 3rd ASPIC International congress, 2018. Teixeira, Jose; Amorim, Ricardo; Santos, Katia; Sardão, Vilma; Soares, Pedro; Serafim, Teresa; Garrido, Jorge; Oliveira, Paulo; Borges, Fernanda. "In vitro characterization of potential biological applications of MITOK3, A NOVEL Mitocondriotropic Menadione derivative, EpiChemBio (CM1406) and MuTaLig (CA15135)". Paper presented in COST actions joint meeting 2017, Porto, Portugal,, 2017. Sardão, Vilma; Bento, Guida; Oliveira, Paulo. "Mitochondrial bioenergetic profile of human urine-derived stem cells.". Paper presented in MitoPorto ¿ Advances in mitochondrial research, International symposium, University of Porto, Portugal, 2017. Teixeira, Jose; Amorim, Ricardo; Santos, Katia; Soares, Pedro; Sardão, Vilma; Serafim, Teresa; Garrido, Jorge; Borges, Fernanda; Oliveira, Paulo. "Improvement of menadione cytotoxic potential by a mitochondria-targeted strategy.". Paper presented in MitoPorto: Advances in Mitochondrial Research International Symposium, University of Porto, Portugal, 2017. Costa, Cláudio; Maleita, Joana; Deus, Cláudia M.; Pereira, Susana P; Serafim, Teresa; Sardão, Vilma; Oliveira, Paulo; Cunha-Oliveira, Teresa. "Characterization of mitochondrial parameters in cell lines in the presence or absence of glucose. Bioenergetic Analysis: establishment and characterization of new models.". Paper presented in MitoPorto - Advances in Mitochondrial Research, University of Porto, Portugal,, 2017. Serafim, Teresa; Pinho, Sónia; Martins, Tatiana R; Sardão, Vilma; Grilo, Luís F.; Cavallaro, Chiara H.; Yang, Shanshan; et al. "Impact of Maternal Obesity During Pregnancy on Fetal Hepatic Redox Profile and Quality Control Proteins.". Paper presented in MitoPorto - Advances in Mitochondrial Research, Porto, Portugal. University of Porto, Portugal, 2017. Serafim, Teresa; Deus, Cláudia M.; Cunha-Oliveira, Teresa; Sardão, Vilma; Cunha, Pedro; Veloso, Caroline; Costa, Daniela; et al. "Stimulation of mitochondrial metabolism in human breast cancer cells results in increased cell motility and decreased resistance to metabolic inhibitors.". Paper presented in MitoPorto - Advances in mitochondrial research, International Symposium, Porto, University of Porto, Portugal, 2017. Campos, J.; Pereira, Francisco; Costa, Ernesto; Sardão, Vilma; Cunha-Oliveira, Teresa; Silva, T.B.; Simões, Rui F.; et al. "Extracting Knowledge from Data to Predict Mitochondrial Toxicity Indexes for Pharmacological Compounds". Paper presented in MitoPorto - Advances in mitochondrial research. International symposium, 2017. Sardão, Vilma; Silva, T.B.; Simões, Rui F.; Oliveira, Paulo; Veloso, Caroline; Valente, M.J.; Silva, R.S.; et al. "Parkinson¿s disease therapy with improved Catechol O-Methyltransferase (COMT) inhibitors display lower mitochondrial liabilitie". Paper presented in MitoPorto - Advances in mitochondrial research. International symposium, 2017. Gomes, Cátia; Teixeira, José; Oliveira, Paulo J.; Ferreira, Isabel C. F. R.; Ramalho-Santos, João; Azul, Anabela Marisa. "Effects of edible mushroom extracts on palmitic acid-induced lipotoxicity in human HepG2 cells". Paper presented in MitoPorto - Advances in Mitochondrial Research: https://sites.google.com/site/mitoporto2018/, 2017. Bento, Guida; Oliveira, Paulo; Sardão, Vilma. "A Protocol for Human Urine-derived Stem Cells Isolation, Expansion, and Mitochondrial Function Profile Analysis.". Paper presented in 51th Annual Meeting of the European Society for Clinical Investigation, Genoa, Italy, 2017. Sardão, Vilma; Silva, Tiago B.,; Simões, Rui; Oliveira, Paulo; Vamente, Maria J.; Silva, Renata S.; Remião, Fernando; Borges, Fernanda. "Developing a Novel Generation of Catechol O-Methyltransferase (COMT) Inhibitors Without Mitochondrial Liabilities for the Therapy of Parkinson¿s Disase". Paper presented in 7th World Congress on Tergeting Mitochondria, 2016. André, Ferreira; Simões, Rui F.; Vilaça, A.; Carvalho, F.S.; Garcia, R.; Burgeiro, Ana; Cunha-Oliveira, Teresa; Oliveira, Paulo. "Decreased global DNA methylation levels and gene expression patterns related metabolic end epigenetic remodeling enzymes are observed after Doxorubicin sub-chronic treatment". Paper presented in 50th Annual Scientific Meeting of the European Society for Clinical Investigation, 2016. Serafim, Teresa; Teresa Cunha-Oliveira; Sardão, Vilma; Deus, Cláudia M.; Greene, Amy; Perkins, Edward; Oliveira, Paulo. "Characterization of Mitochondria of Breast Cancer Cell Lines.". Paper presented in XVIII Congress of the Portuguese Biochemical Society, 2014. Branco, Ana F.; Sampaio, Susana F.; Sardão, Vilma; Gonzales, Susana; Oliveira, Paulo. "Isoproterenol-induced toxicity on H9c2 myoblasts depends on the differentiation status". Paper presented in 47th Annual Meeting of the European Society for Clinical Investigation, Albufeira, Portugal April 17-20, 2013, 2013. Serafim, Teresa; Sardão, Vilma; Greene, Amy; Perkins, Edward; Santos, Maria S.; Oliveira, Paulo. "Profilling mitochondrial physiology in commercial human cancer cell line for evaluating coumpound anticancer activity". Paper presented in 47th Annual Meeting of the European Society for Clinical Investigation, Albufeira, Portugal, 2013. Sampaio, Susana; Moreira, Ana C.; Branco, Ana; Santos, Maria S.; Oliveira, Paulo; Sardão, Vilma. "Apoptosis-inducing Factor (AIF) Role in Anthracycline-Induced Cardiomyoblast Cell Death". Paper presented in OCC conferences: Oxidants and Antioxidants in Biology ¿ Cell Signaling and Nutrient-Gene Interactions, Alba, Italy,, 2012. Sampaio, Susana; Moreira, Ana C.; Santos, Maria S.; Oliveira, Paulo; Sardão, Vilma. "Role of the Apoptosis-inducing Factor (AIF) on Doxorubicin-induced Cardiomyoblast Cell Death". Paper presented in 6th National Meeting on Cell Signaling, Braga, Portugal, 2012. Silva, Ana M.; Oliveira, Paulo; Moreira, Ana C.; Santos, Maria S.; Sardão, Vilma. "Are phytoestrogens able to prevent lipotoxicity in cardiac cells?". Paper presented in 46th Annual Scientific Meeting of the European Society for Clinical Investigation, Budapest, Hungary, 2012. Serafim, Teresa; Sardão, Vilma; Greene, Amy; Perkins, Edward; Santos, Maria S.; Oliveira, Paulo. "Mitochondrial characterization of breast cancer cell lines for chemotherapeutic in vitro studies.". Paper presented in AACR Special Conference: Metabolism and Cancer, Baltimore, USA, 2011. Moreira, Ana C.; Branco, Ana F.; Oliveira, Paulo; Sardão, Vilma. "Caspase-independent apoptosis induced by Doxorubicin on Embryonic Ventricular H9c2 Myoblasts ¿ Role of Apoptosis Inducing Factor (AIF) and Endonuclease G". Paper presented in 44th Annual Scientific Meeting of the European Society for Clinical Investigation, Bari, Italy, 2010. Gonçalves, Inês; Carneiro, D.; Lumini-Oliveira, José; Machado, Nuno; Marques, F.; Sardão, Vilma; Oliveira, Paulo; Magalhães, José; Ascensão, António. "Effects of acute endurance exercise on heart and liver mitochondrial function in rats treated with Doxorubicin". Paper presented in 3rd Meeting of Young Researchers of University of Porto, Porto, Portugal, 2010. Branco, Ana F.; Moreira, Ana C.; Pereira, Susana P; Sardão, Vilma; Oliveira, Paulo. "Toxicity of Isoproterenol Increases with the Differentiation State of H9c2 Myoblasts". Paper presented in 49th ASCB Annual Meeting, San Diego, CA, USA, 2009. Braga, Teresa M.; Marques, J.; Almeida Paz, Filipe A.; Pillinger, M.; Branco, A.F.; Sardão, Vilma; Diogo, C.V.; et al. "Nano-encapsulation of Antitumoral Metal Drug Candidates using Cyclodextrins". Paper presented in Nanomedicine 2009 ¿ 2nd European Summer School in Nanomedicine, 2009. Branco, Ana F.; Moreira, Ana C.; Holy, Jon; Wallace, Kendall B.; Oliveira, Paulo; Sardão, Vilma. "Differential Sensitivity of Undifferentiated and Differentiated H9c2 Myoblasts to the Cardiotoxicant Doxorubicin". Paper presented in Molecular Regulation of Cardiac Disease Symposium, London, UK,, 2009. Serafim, Teresa; Sardão, Vilma; Matos, Júlio A.; Pereira, Gonçalo C.; Branco, Ana F.; Pereira, Sandro L.; Parke, Donna; et al. "Sanguinarine Inhibits the Proliferation of Metastatic Melanoma Cells by Nuclear and Mitochondrial Effects". Paper presented in Chemistry in Cancer Research: A Vital Partnership in Cancer Drug Discovery and Development, New Orleans, Louisiana, USA, 2009. Silva, Filomena S.G.; Sardão, Vilma; Oliveira, Paulo; Santos, Maria S.; Sousa, Maria do Céu; Santos-Silva, Alice; Pereira, Petronila Rocha. "Effects of 13-cis-RA and acitretin on tumor cell proliferation and isolated liver mitochondria". Paper presented in 16th National Congress of Biochemistry, Ponta Delgada, São Miguel, Açores, Portugal, 2008. Silva, João P.; Sardão, Vilma; Proença, Fernanda; Coutinho, Olga P.; Oliveira, Paulo. "Nitrogen compounds as protectors of oxidative damage induced in H9c2 myoblasts". Paper presented in 16th Euroconference on Apoptosis & 5th Swiss Apoptosis Meeting, Bern, Switzerland,, 2008. Sardão, Vilma; Oliveira, Paulo; Holy, Jon; Oliveira, Catarina R.; Wallace, Kendall B.. "Doxorubicin Toxicity in H9c2 Embryonic Cardiomyoblasts: Morphological Alterations and Activation of p53-Bax Signaling Pathway". Paper presented in 6th Annual meeting of the Society for Heart and Vascular Metabolism, Boston, Massachusetts, USA, 2008. Branco, Ana F.; Sardão, Vilma; Pereira, Sandro L.; Holy, Jon; Oliveira, Catarina R.; Wallace, Kendall B.; Oliveira, Paulo. "Differentiation of H9c2 embrionic ventricular cells results into increased susceptibility to the cardiac toxicants dosorubicin and isoproterenol". Paper presented in 6th Annual meeting of the Society for Heart and Vascular Metabolism, Boston, Massachusetts, USA, 2008. Amaral, Sandra; Mota, Paula C; Lacerda, Beatriz; Oliveira, Paulo; Ramalho-Santos, João; Martins, Luís. "Mitochondrial testicular function: effects of age". Paper presented in 15th European testis workshop (Naantali, Finland), 2008. Mota, Paula C; Martins, Luís; Amaral, Sandra; Oliveira, Paulo; Ramalho-Santos, João. "Characterization of mitochondrial bioenergetics of cat testicular cells: variations with age and other functions". Paper presented in 15th European testis workshop" ( Naantali, Finland), 2008. Pereira, Sandro L.; Sardão, Vilma; Branco, Ana F.; Holy, Jon; Oliveira, Catarina R.; Wallace, Kendall B.; Oliveira, Paulo. "Toxicity of Doxorubicin and Isoproterenol Depends on the Differentiation Stage of H9c2 Myoblasts". Paper presented in Society of Toxicology Annual Meeting 2008, Seattle, WA, EUA, 2008. Sardão, Vilma; Oliveira, Paulo; Holy, Jon; Oliveira, Catarina R.; Wallace, Kendall B.. "Doxorubicin induces Apoptosis in H9c2 myoblasts ¿ Contribution of P53/Bax pathways and oxidative stress". Paper presented in Apoptosis World 2008, From Mechanisms to Applications, Luxembourg, 2008. Branco, Ana F.; Pereira, Sandro L.; Sardão, Vilma; Wallace, Kendall B.; Oliveira, Paulo. "Apoptotic effect of isoproterenolon H9c2 myoblasts: Relevance of differentiation State". Paper presented in Apoptosis World 2008, From Mechanisms to Applications, Luxembourg,, 2008. Serafim, Teresa; Sardão, Vilma; Carvalho, Filipa S.; Marques, Maria P.; Garrido, Jorge; Milhazes, Nuno; Borges, Fernanda; et al. "Antiproliferative activity of ferulic and caffeic acid derivatives on tumor cell lines ¿ Structure-function relations and direct effects on mitochondria". Paper presented in Apoptosis World 2008, From Mechanisms to Applications, Luxembourg, 2008. Sardão, Vilma; Oliveira, Paulo; Holy, Jon; Oliveira, Catarina R.; Wallace, Kendall B.. "Morphological Hallmarks of Doxorubicin Toxicity on H9c2 Myoblasts: The pro-oxidant action of the antineoplastic agent". Paper presented in European Meeting of the Society for Free Radical Research, Vilamoura, Portugal, 2007. Braga, Susana S.; Mokal, Vijaya; Paz, Filipe A. A.; Marques, Maria P. M.; Branco, Ana F.; Sardão, Vilma; Oliveira, Paulo; et al. "Cyclodextrin encapsulation of biomimetic organometallic cancer drud candidates". Paper presented in 6th International Medicinal Chemistry Symposium, Istanbul, Turkey, 2007. Mota, Paula C; Martins, Luís; Amaral, Sandra; Oliveira, Paulo; Ramalho-Santos, João. "Characterization of the mitochondrial membrane potential in domestic cat testicular cells: possible implications for germ cell function". Paper presented in 40th Annual Meeting of the Society for the Study of Reproduction¿ (San Antonio, Texas, USA), 2007. Sardão, Vilma; Oliveira, Paulo; Holy, Jon; Oliveira, Catarina R.; Wallace, Kendall B.. "Morphologic Alterations Induced by the Antineoplastic Agent Doxorubicin in H9c2 myoblasts: Relevance for Doxorubicin Cardiotoxicity". Paper presented in First Iberic Meeting on Medicinal Chemistry ¿ Anticancer Agents, Regua, Portugal, 2007. Serafim, Teresa; Sardão, Vilma; Holy, Jon; Marques, Maria P.; Batista de Carvalho, Luís A.E.; Garrido, Jorge; Milhazes, Nuno; et al. "Anti-proliferative profile of potential lipophilic antioxidants structurally based on the dietary antioxidants ferulic and caffeic acids". Paper presented in First Iberic Meeting on Medicinal Chemistry ¿ Anticancer Agents, Regua, Portugal, 2007. Sardão, Vilma; Oliveira, Paulo; Holy, Jon; Oliveira, Catarina R.; Wallace, Kendall B.. "The H9c2 cell Line as a Model for Cardiotoxicology Studies ¿ Imaging of Cell Dysfunction Induced By Tert-Butylhydroperoxide". Paper presented in XV National Congress of Biochemistry, Aveiro, Portugal, 2006. Pereira, Gonçalo C.; Serafim, Teresa; Sardão, Vilma; Teles, Ana I.; Moreno, António J. M.; Parke, Donna; Perkins, Edward; Holy, Jon; Oliveira, Paulo. "Berberine-induced Mitochondrial Depolarization and Fragmentation in K1735-M2 Rat Melanoma Cells ¿ A Possible Mechanism for Berberine Anti-proliferative / Pro-apoptotic actions". Paper presented in XV National Congress of Biochemistry, Aveiro, Portugal, 2006. Matos, Júlio A.; Serafim, Teresa; Sardão, Vilma; Branco, Ana F.; Moreno, António J. M.; Parke, Donna; Perkins, Edward; Holy, Jon; Oliveira, Paulo. "Mitochondrial Involvement in Sanguinarine-Induced Apoptosis". Paper presented in XV National Congress of Biochemistry, Aveiro, Portugal, 2006. Marques, Maria P.; Amado, A.M.; Fiuza, S.M.; Oliveira, Paulo; Sardão, Vilma; Soares, Ana S; Urbano, Ana M.; Batista De Carvalho, L.A.E.. "Polynuclear Pt(II) and Pd(II) Polyamine Complexes as Novel Anticancer Agents,". Paper presented in XXXVII Meeting of Portuguese Society of Pharmacology, 2006, Porto, Portugal, 2006. Moreira, Ana C.; Branco, Ana F.; Holy, Jon; Oliveira, Paulo; Santos, Maria S.; Sardão, Vilma. "Role of the Apoptosis Inducing Factor and Endonuclease G in the Cytotoxicity of Doxorubicin on Embryonic Ventricular H9c2 cells". Paper presented in 7th Annual meeting of the Society for Heart and Vascular Metabolism, Padova, Italy, 2006. Fiuza, Sónia; Amado, Ana M; Oliveira, Paulo; Sardão, Vilma; Marques, Maria P.; Batista de Carvalho, Luís A.E.. "Pt(II) and Pd(II) Complexes with Biogenic Amines - Structure-Activity Study". Paper presented in First European Conference on Chemistry for Life Sciences. Rimini, Italy, 2005. Fiuza, Sónia; Amado, Ana M.; Oliveira, Paulo; Sardão, Vilma; Marques, Maria P.; Batista de Carvalho, Luis A.E.. "Structure-Activity Study of Pt(II) and Pd(II) Spermidine Complexes". Paper presented in 12th International Conference on Biological Inorganic Chemistry - ICBIC12, Ann Arbor, Michigan, USA, 2005. Sardão, Vilma; Oliveira, Paulo; Monteiro, Pedro; Gonçalves, Lino; Providência, Luís A.; Moreno, Antonio J. M.. "Caffeine Induces Cytochrome c Release and Reduces Cardiac Mitochondrial ATP Production". Paper presented in XXIV Congresso Portugues de Cardiologia , Madeira (Portugal), 2003. Sardão, Vilma; Oliveira, Paulo; Monteiro, Pedro; Gonçalves, Lino; Moreno, António J. M.. "Toxicity of Caffeine in Heart Mitochondria: Enhancement of Permeability Transition and Disturbance of Mitochondrial Bioenergetic Processes". Paper presented in XIII Congresso Português de Bioquímica, Lisboa (Portugal), 2002. Sardão, Vilma; Oliveira, Paulo; Monteiro, Pedro; Gonçalves, Lino; Providência, Luís A.; Moreno, António J. M.. "Mitocôndrias Cardíacas e Cafeína ¿ Desregulação da Homeostase do Cálcio e Interacções com Cadeia Respiratória". Paper presented in XXIII Congresso Português de Cardiologia, Vilamoura, Portugal, 2002. Oliveira, Paulo; Rolo, Anabela P.; Coxito, Pedro; Santos, Dario L.; Sardão, Vilma; Seiça, Raquel; Monteiro, Pedro; et al. "Mitochondria From Diabetic Rats Cardiomyocytes are more resistent to the Induction of Permeability Transition Pore". Paper presented in 2nd European Meeting on Vascular Biology and Medicine, ULM, German, 2001. Sardão, Vilma; Oliveira, Paulo; Monteiro, Pedro; Gonçalves, Lino; Providência, Luís A.; Moreno, António J. M.. "Caffeine Induces Directly the Permeability Transition in Isolated Rat Heart Mitochondria". Paper presented in XXII Congresso Português de Cardiologia, Vilamoura, Portugal, 2001. Oliveira, Paulo; Rolo, Anabela P.; Seiça, Raquel; Sardão, Vilma; Monteiro, Pedro; Gonçalves, Lino; Providência, Luís A.; et al. "Heart Mitochondria From Diabetic Rats Are More Resistant to the Induction of the Mitochondrial Permeability Transition". Paper presented in XXII Congresso Português de Cardiologia, Vilamoura, Portugal, 2001.
Encyclopedia entry	Marques, Mário P.; Mendonça, Laura; Neves, Beatriz G.; Varela, Carla; Oliveira, Paulo; Cabral, Célia. "Pharmacological Wound Healing Evidence of Iberian Lamiaceae". In Scholarly Community Encyclopedia, 2023. https://encyclopedia.pub/entry/41740. Published
Journal article	Ferreiro, Elisabete; Monteiro, Mariana; Pereira, Francisco; Barroso, Cristina; Egas, Conceição; Macedo, Paula; Valero, Jorge; Sardão, Vilma A.; Oliveira, Paulo J.. "Age-dependent energy metabolism and transcriptome changes in urine-derived stem cells". Mechanisms of Ageing and Development 218 (2024): 111912. http://dx.doi.org/10.1016/j.mad.2024.111912. 10.1016/j.mad.2024.111912 Amorim, Ricardo; Magalhães, Carina C.; Benfeito, Sofia; Cagide, Fernando; Tavares, Ludgero C.; Santos, Katia; Sardão, Vilma A.; et al. "Mitochondria dysfunction induced by decyl-TPP mitochondriotropic antioxidant based on caffeic acid AntiOxCIN6 sensitizes cisplatin lung anticancer therapy due to a remodeling of energy metabolism". Biochemical Pharmacology 219 (2024): 115953. http://dx.doi.org/10.1016/j.bcp.2023.115953. 10.1016/j.bcp.2023.115953 Amorim, Ricardo; Chavarria, Daniel; Soares, Pedro; Benfeito, Sofia; Cagide, Fernando; Teixeira, José; Oliveira, Paulo; Borges, Fernanda. "Decreasing the Burden of Non-Alcoholic Fatty Liver Disease: from Therapeutic Targets to Drug Discovery Opportunities". Medicinal Research Reviews (2024): Submitted Aryane Cruz Oliveira Pinho; Diana Santos; Paulo J. Oliveira; Ermelindo Carreira Leal; Eugenia Carvalho. "Real-time OXPHOS capacity analysis in wounded skin from diabetic mice: A pilot study". European Journal of Clinical Investigation (2023): https://doi.org/10.1111/eci.14128. 10.1111/eci.14128 Elsa T. Rodrigues; Eduarda Pereira; Paulo J. Oliveira; Miguel A. Pardal; Rodrigues, Elsa T.; Pereira, Eduarda; Oliveira, Paulo J.; Pardal, Miguel A.. "The H9c2(2-1) cell-based sulforhodamine B assay is a non-animal alternative to evaluate municipal wastewater quality over time". Environmental Monitoring and Assessment 195 11 (2023): https://doi.org/10.1007/s10661-023-12017-8. 10.1007/s10661-023-12017-8 Cavaleiro, Carla; Afonso, Gonçalo J. M.; Oliveira, Paulo J.; Valero, Jorge; Mota, Sandra I.; Ferreiro, Elisabete. "Urine-derived stem cells in neurological diseases: current state-of-the-art and future directions". Frontiers in Molecular Neuroscience 16 (2023): http://dx.doi.org/10.3389/fnmol.2023.1229728. 10.3389/fnmol.2023.1229728 Pereira, Susana P.; Diniz, Mariana S.; Tavares, Ludgero C.; Cunha-Oliveira, Teresa; Li, Cun; Cox, Laura A.; Nijland, Mark J.; Nathanielsz, Peter W.; Oliveira, Paulo J.. "Characterizing Early Cardiac Metabolic Programming via 30% Maternal Nutrient Reduction during Fetal Development in a Non-Human Primate Model". International Journal of Molecular Sciences 24 20 (2023): 15192. http://dx.doi.org/10.3390/ijms242015192. 10.3390/ijms242015192 Luís F. Grilo; João D. Martins; Mariana S. Diniz; Carolina Tocantins; Chiara H. Cavallaro; Inês Baldeiras; Teresa Cunha-Oliveira; et al. "Maternal hepatic adaptations during obese pregnancy encompass lobe-specific mitochondrial alterations and oxidative stress". Clinical Science 137 17 (2023): 1347-1372. https://doi.org/10.1042/CS20230048. 10.1042/CS20230048 Monteiro-Alfredo, Tamaeh; dos Santos, Jéssica Maurino; Antunes, Kátia Ávila; Cunha, Janielle; da Silva Baldivia, Debora; Pires, Ana Salomé; Marques, Inês; et al. "Acrocomia aculeata associated with doxorubicin: cardioprotection and anticancer activity". Frontiers in Pharmacology 14 (2023): http://dx.doi.org/10.3389/fphar.2023.1223933. 10.3389/fphar.2023.1223933 Tocantins, Carolina; Martins, João D.; Rodrigues, Óscar M.; Grilo, Luís F.; Diniz, Mariana S.; Stevanovic-Silva, Jelena; Beleza, Jorge; et al. "Metabolic mitochondrial alterations prevail in the female rat heart 8¿weeks after exercise cessation". European Journal of Clinical Investigation 53 11 (2023): http://dx.doi.org/10.1111/eci.14069. 10.1111/eci.14069 Quatorze, Marta; Silva, Filomena; Duarte, Ana I.; Cardoso, João; Caetano, Carolina; Ramalho-Santos, João; Oliveira, Paulo J.; Amaral, Sara Varela. "Amyotrophic Lateral Sclerosis: When Nerve Cells Run Out of Power". Frontiers for Young Minds 11 (2023): http://dx.doi.org/10.3389/frym.2023.974736. Published • 10.3389/frym.2023.974736 Amorim, Ricardo; Magalhães, Carina C.; Borges, Fernanda; Oliveira, Paulo J.; Teixeira, José. Corresponding author: Amorim, Ricardo. "From Non-Alcoholic Fatty Liver to Hepatocellular Carcinoma: A Story of (Mal)Adapted Mitochondria". Biology 12 4 (2023): 595. http://dx.doi.org/10.3390/biology12040595. 10.3390/biology12040595 Bessa, Cláudia; Loureiro, Joana B.; Barros, Matilde; Isca, Vera M. S.; Sardão, Vilma A.; Oliveira, Paulo J.; Bernardino, Raquel L.; et al. "Counteracting Colon Cancer by Inhibiting Mitochondrial Respiration and Glycolysis with a Selective PKCd Activator". International Journal of Molecular Sciences 24 6 (2023): 5710. http://dx.doi.org/10.3390/ijms24065710. 10.3390/ijms24065710 Diana Sousa; Mariana Rocha; Andreia Marreiros Amaro; Marcos Divino Ferreira-Junior; Keilah Valéria Naves Cavalcante; Tamaeh Monteiro-Alfredo; Tamaeh Monteiro Alfredo; Cátia Barra; et al. "Exposure to Obesogenic Environments during Perinatal Development Modulates Offspring Energy Balance Pathways in Adipose Tissue and Liver of Rodent Models". Nutrients (2023): https://www.mdpi.com/2072-6643/15/5/1281. 10.3390/nu15051281 Mário P. Marques; Laura Mendonça; Beatriz G. Neves; Carla Varela; Paulo Oliveira; Célia Cabral. "Exploring Iberian Peninsula Lamiaceae as Potential Therapeutic Approaches in Wound Healing". Pharmaceuticals (2023): https://doi.org/10.3390/ph16030347. 10.3390/ph16030347 Sofia Benfeito; Carlos Fernandes; Daniel Chavarria; Sandra Barreiro; Fernando Cagide; Lisa Sequeira; José Teixeira; et al. "Modulating Cytotoxicity with Lego-like Chemistry: Upgrading Mitochondriotropic Antioxidants with Prototypical Cationic Carrier Bricks". Journal of Medicinal Chemistry (2023): https://doi.org/10.1021/acs.jmedchem.2c01630. 10.1021/acs.jmedchem.2c01630 José P. Castelão-Baptista; Sara Valente; Sara Canário; David Oppolzer; A.I.R.N.A.Barros; Carlos Venâncio; Tânia Martins; et al. "Brassica oleracea Var italica by-Products Prevent Lipid Accumulation and Cell Death in a Liver Cell Model of Lipid Toxicity". Nutrients (2023): https://www.mdpi.com/2072-6643/15/4/924. 10.3390/nu15040924 Inês Ramos Rego; Daniela Silverio; Maria Isabel Eufrásio; Sandra Sofia Pinhanços; Bruna Lopes da Costa; José Carlos Santos Teixeira; Hugo Fernandes; et al. "TRAP1 Is Expressed in Human Retinal Pigment Epithelial Cells and Is Required to Maintain their Energetic Status". Antioxidants (2023): https://www.mdpi.com/2076-3921/12/2/381. 10.3390/antiox12020381 Jelena Stevanovic-Silva; Jorge Beleza; Pedro Coxito; Paulo J. Oliveira; António Ascensão; José Magalhães. "Gestational Exercise Antagonises the Impact of Maternal High-Fat High-Sucrose Diet on Liver Mitochondrial Alterations and Quality Control Signalling in Male Offspring". International Journal of Environmental Research and Public Health (2023): https://doi.org/10.3390/ijerph20021388. 10.3390/ijerph20021388 Chouvarine, Philippe; Hysko, Klea; Chan, Stephen Y.; Oliveira, Paulo; Maron, Bradley A.; Kourembanas, Stella; Hansmann, Georg. "Second International Pulmonary Hypertension/Heart Failure Symposium—Structural heart disease, right ventricular dysfunction, and stem cell therapy: The European Pediatric Pulmonary Vascular Disease Network". Pulmonary Circulation 13 1 (2023): http://dx.doi.org/10.1002/pul2.12175. 10.1002/pul2.12175 Soares, Pedro; Chavarria, Daniel; Silva, Catia; Silva, Filomena S.G.; Oliveira, Paulo J.; Borges, Fernanda. "Drug discovery and amyotrophic lateral sclerosis: Emerging challenges and therapeutic opportunities". Ageing Research Reviews 83 (2023): 101790. http://dx.doi.org/10.1016/j.arr.2022.101790. 10.1016/j.arr.2022.101790 Diniz, Mariana S; Hiden, Ursula; Falcão-Pires, Inês; Oliveira, Paulo J; Sobrevia, Luis; Pereira, Susana P; Diniz, Mariana S.; Oliveira, Paulo J.; Pereira, Susana P.. "Fetoplacental endothelial dysfunction in gestational diabetes mellitus and maternal obesity: A potential threat for programming cardiovascular disease". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1869 8 (2023): 166834. http://hdl.handle.net/10316/108720. https://doi.org/10.1016/j.bbadis.2023.166834 Luís F. Grilo; Susana P. Pereira; Oliveira, Paulo J.; Cun Li; Kenneth Lange; Jeremy P. Glenn ; Kip D. Zimmerman ; Nathanielsz, Peter W.; Cox, Laura A.. "Maternal obesity and reduced maternal nutrition during fetal development differentially result in altered cardiac transcriptome regulating cardiomyocyte maturation, proliferation, and enlargement at late gestation.". Cellular and Molecular Life Sciences (2023): Submitted Chavarria, Daniel; Benfeito, Sofia; Soares, Pedro; Lima, Carla; Garrido, Jorge; Serrão, Paula; Soares-da-Silva, Patrício; et al. Corresponding author: Borges, Fernanda. "Boosting caffeic acid performance as antioxidant and monoamine oxidase B/catechol-O-methyltransferase inhibitor". European Journal of Medicinal Chemistry 243 (2022): 114740. http://dx.doi.org/10.1016/j.ejmech.2022.114740. 10.1016/j.ejmech.2022.114740 Afonso, Marta B.; Islam, Tawhidul; Magusto, Julie; Amorim, Ricardo; Lenoir, Véronique; Simões, Rui F.; Teixeira, José; et al. "RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease". Hepatology 77 4 (2022): 1319-1334. http://dx.doi.org/10.1002/hep.32756. 10.1002/hep.32756 Carlos Fernandes; Fernando Cagide; Jorge Simões; Carlos Pita; Eurico Pereira; Afonso J. C. Videira; Pedro Soares; et al. "Targeting Hydroxybenzoic Acids to Mitochondria as a Strategy to Delay Skin Ageing: An In Vitro Approach". Molecules (2022): https://doi.org/10.3390/molecules27196183. 10.3390/molecules27196183 Amorim, Ricardo; Simões, Inês C.M.; Teixeira, José; Cagide, Fernando; Potes, Yaiza; Soares, Pedro; Carvalho, Adriana; et al. "Mitochondria-targeted anti-oxidant AntiOxCIN4 improved liver steatosis in Western diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation, quality control mechanism and antioxidant defense systems". Redox Biology 55 (2022): 102400. http://dx.doi.org/10.1016/j.redox.2022.102400. 10.1016/j.redox.2022.102400 Emiliano Panieri; Sónia A. Pinho; Gonçalo J. M. Afonso; Paulo J. Oliveira; Teresa Cunha-Oliveira; Luciano Saso. "NRF2 and Mitochondrial Function in Cancer and Cancer Stem Cells". Cells (2022): https://doi.org/10.3390/cells11152401. 10.3390/cells11152401 Albertini, Claudia; Salerno, Alessandra; Atzeni, Silvia; Uliassi, Elisa; Massenzio, Francesca; Maruca, Annalisa; Rocca, Roberta; et al. "Riluzole-Rasagiline Hybrids: Toward the Development of Multi-Target-Directed Ligands for Amyotrophic Lateral Sclerosis". ACS Chemical Neuroscience (2022): http://dx.doi.org/10.1021/acschemneuro.2c00261. 10.1021/acschemneuro.2c00261 Cláudia M. Deus; José Teixeira; Nuno Raimundo; Paolo Tucci; Fernanda Borges; Luciano Saso; Paulo J. Oliveira. "Modulation of cellular redox environment as a novel therapeutic strategy for Parkinson's disease". European Journal of Clinical Investigation (2022): https://doi.org/10.1111/eci.13820. 10.1111/eci.13820 Alves-Silva, Jorge M.; Zuzarte, Mónica; Marques, Carla; Viana, Sofia; Preguiça, Inês; Baptista, Rui; Ferreira, Cátia; et al. "1,8-Cineole ameliorates right ventricle dysfunction associated with pulmonary arterial hypertension by restoring connexin43 and mitochondrial homeostasis". Pharmacological Research 180 (2022): 106151. http://dx.doi.org/10.1016/j.phrs.2022.106151. 10.1016/j.phrs.2022.106151 Teresa Cunha-Oliveira; Daniela Franco Silva; Luis Segura; Inês Baldeiras; Ricardo Marques; Tatiana Rosenstock; Paulo J. Oliveira; Filomena S. G. Silva. "Redox profiles of amyotrophic lateral sclerosis lymphoblasts with or without known SOD1 mutations". European Journal of Clinical Investigation (2022): https://doi.org/10.1111/eci.13798. 10.1111/eci.13798 Sónia A. Pinho; Cláudio F. Costa; Cláudia M. Deus; Sonia L. C. Pinho; Inês Miranda-Santos; Gonçalo Afonso; Olivia Bagshaw; et al. "Mitochondrial and metabolic remodelling in human skin fibroblasts in response to glucose availability". The FEBS Journal (2022): https://doi.org/10.1111/febs.16413. 10.1111/febs.16413 Anabela Marisa Azul; Martin Winter; Daniel Silva; Liljana Georgievska; Paulo J. Oliveira. "Bioenergetic remodeling in the pathophysiology and treatment of nonalcoholic fatty liver disease". European Journal of Clinical Investigation (2022): https://doi.org/10.1111/eci.13749. 10.1111/eci.13749 João Campos Santos; Carla Cruz Marques; Maria Conceição Baptista; Jorge Pimenta; José Carlos Santos Teixeira; Liliana Montezinho; Fernando Cagide; et al. "Effect of a Novel Hydroxybenzoic Acid Based Mitochondria Directed Antioxidant Molecule on Bovine Sperm Function and Embryo Production". Animals (2022): https://www.mdpi.com/2076-2615/12/7/804. 10.3390/ani12070804 Paulo J Oliveira. "The heart of FOIE GRAS and mtFOIE GRAS: fundamental and clinical investigation for training and innovation in non-alcoholic fatty liver disease". European Heart Journal (2022): https://doi.org/10.1093/eurheartj/ehab399. 10.1093/eurheartj/ehab399 Amorim, Ricardo; Cagide, Fernando; Tavares, Ludgero C.; Simões, Rui F.; Soares, Pedro; Benfeito, Sofia; Baldeiras, Inês; et al. "Mitochondriotropic antioxidant based on caffeic acid AntiOxCIN4 activates Nrf2-dependent antioxidant defenses and quality control mechanisms to antagonize oxidative stress-induced cell damage". Free Radical Biology and Medicine 179 (2022): 119-132. http://dx.doi.org/10.1016/j.freeradbiomed.2021.12.304. 10.1016/j.freeradbiomed.2021.12.304 Melim, Catarina; Lauro, Maria R.; Pires, Isabel M.; Oliveira, Paulo J.; Cabral, Célia; Catarina Melim; Maria R. Lauro; et al. "The Role of Glucosinolates from Cruciferous Vegetables (Brassicaceae) in Gastrointestinal Cancers: From Prevention to Therapeutics". Pharmaceutics (2022): http://hdl.handle.net/10316/103454. https://doi.org/10.3390/pharmaceutics14010190 Simões, Rui F.; Oliveira, Paulo J.; Oliveira, Teresa Cunha; Pereira, Francisco B.; Rui F. Simões; Paulo J. Oliveira; Teresa Cunha-Oliveira; Francisco B. Pereira. "Evaluation of 6-Hydroxydopamine and Rotenone In Vitro Neurotoxicity on Differentiated SH-SY5Y Cells Using Applied Computational Statistics". International Journal of Molecular Sciences 23 6 (2022): 3009-3009. http://hdl.handle.net/10316/103323. https://doi.org/10.3390/ijms23063009 Rui F. Simões; Rute Pino; Maurício Moreira-Soares; Jaromira Kovarova; Jiri Neuzil; Rui Travasso; Paulo J. Oliveira; Teresa Cunha-Oliveira; Francisco B. Pereira. "Quantitative analysis of neuronal mitochondrial movement reveals patterns resulting from neurotoxicity of rotenone and 6-hydroxydopamine". The FASEB Journal 35 12 (2021): https://doi.org/10.1096/fj.202100899R. 10.1096/fj.202100899R Dias-Pedroso, Daniela; Ramalho, José S.; Sardão, Vilma A.; Jones, John G.; Romão, Carlos C.; Oliveira, Paulo J.; Vieira, Helena L.A.. "Carbon Monoxide-Neuroglobin Axis Targeting Metabolism Against Inflammation in BV-2 Microglial Cells". Molecular Neurobiology (2021): http://dx.doi.org/10.1007/s12035-021-02630-4. 10.1007/s12035-021-02630-4 Carlos Fernandes; Afonso J. C. Videira; Caroline D. Veloso; Sofia Benfeito; Pedro Soares; João D. Martins; Beatriz Gonçalves; et al. "Cytotoxicity and Mitochondrial Effects of Phenolic and Quinone-Based Mitochondria-Targeted and Untargeted Antioxidants on Human Neuronal and Hepatic Cell Lines: A Comparative Analysis". Biomolecules 11 11 (2021): 1605-1605. https://doi.org/10.3390/biom11111605. 10.3390/biom11111605 Luís F. Grilo; Carolina Tocantins; Mariana S. Diniz; Rodrigo Mello Gomes; Paulo J. Oliveira; Paulo Matafome; Susana P. Pereira. "Metabolic Disease Programming: From Mitochondria to Epigenetics, Glucocorticoid Signalling and Beyond". European Journal of Clinical Investigation (2021): https://doi.org/10.1111/eci.13625. 10.1111/eci.13625 Cláudia M. Deus; Susana P. Pereira; Teresa Cunha-Oliveira; José Teixeira; Rui F. Simões; Fernando Cagide; Sofia Benfeito; et al. "A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients". Redox Biology 45 (2021): 102037-102037. https://doi.org/10.1016/j.redox.2021.102037. 10.1016/j.redox.2021.102037 Amorim, Ricardo; Simões, Inês; Veloso, Caroline; Marques-Carvalho, Adriana; Simões, Rui; Pereira, Francisco; Thiel, Theresa; et al. "Exploratory Data Analysis of Cell and Mitochondrial High-Fat, High-Sugar Toxicity on Human HepG2 Cells". Nutrients 13 5 (2021): 1723. http://dx.doi.org/10.3390/nu13051723. 10.3390/nu13051723 Rui F. Simões; Rafaela Ferrão; Margarida R. 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Journal of Biochemical and Molecular Toxicology 21 2 (2007): 53-61. http://www.scopus.com/inward/record.url?eid=2-s2.0-34247399590&partnerID=MN8TOARS. 10.1002/jbt.20159 Oliveira, P.J.. "Response [2]". Journal of Biochemical and Molecular Toxicology 21 6 (2007): http://www.scopus.com/inward/record.url?eid=2-s2.0-36749085079&partnerID=MN8TOARS. 10:1002/jbt Pereira, G.C.. "Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: Comparison with direct effects on isolated mitochondrial fractions". Journal of Pharmacology and Experimental Therapeutics 323 2 (2007): 636-649. http://www.scopus.com/inward/record.url?eid=2-s2.0-35548974344&partnerID=MN8TOARS. 10.1124/jpet.107.128017 Oliveira, P.J.. "Doxorubicin-induced thiol-dependent alteration of cardiac mitochondrial permeability transition and respiration". Biochemistry (Moscow) 71 2 (2006): 194-199. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645277082&partnerID=MN8TOARS. 10.1134/S000629790602012X Oliveira, P.J.. "Depletion of adenine nucleotide translocator protein in heart mitochondria from doxorubicin-treated rats - Relevance for mitochondrial dysfunction". Toxicology 220 2-3 (2006): 160-168. http://www.scopus.com/inward/record.url?eid=2-s2.0-33244492919&partnerID=MN8TOARS. 10.1016/j.tox.2005.12.009 Teodoro, J.. "Decreased ANT content in Zucker fatty rats: Relevance for altered hepatic mitochondrial bioenergetics in steatosis". FEBS Letters 580 8 (2006): 2153-2157. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645241135&partnerID=MN8TOARS. 10.1016/j.febslet.2006.02.078 Fiuza, S.M.. "Pt(II) vs Pd(II) polyamine complexes as new anticancer drugs: A structure-activity study". Letters in Drug Design and Discovery 3 3 (2006): 149-151. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645876182&partnerID=MN8TOARS. 10.2174/157018006776286989 O'Brien, T.M.. "Esterification prevents induction of the mitochondrial permeability transition by N-acetyl perfluorooctane sulfonamides". Chemical Research in Toxicology 19 10 (2006): 1305-1312. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750209492&partnerID=MN8TOARS. 10.1021/tx060132r Ascensão, A.. "Endurance training limits the functional alterations of heart rat mitochondria submitted to in vitro anoxia-reoxygenation". International Journal of Cardiology 109 2 (2006): 169-178. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646109584&partnerID=MN8TOARS. 10.1016/j.ijcard.2005.06.003 Ascensão, A.; Ascensão A; Ferreira R; Oliveira PJ; Magalhães J. "Effects of endurance training and acute doxorubicin treatment on rat heart mitochondrial alterations induced by in vitro anoxia-reoxygenation". Cardiovascular Toxicology 6 3-4 (2006): 159-171. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947101036&partnerID=MN8TOARS. 10.1385/ct:6:3:159 Oliveira PJ; Oliveira, P.J.. "Cardiac mitochondrial alterations observed in hyperglycaemic rats--what can we learn from cell biology?". Current diabetes reviews 1 1 (2005): 11-21. http://europepmc.org/abstract/med/18220578. 10.2174/1573399052952578 Ferreira M; Coxito PM; Sardão VA; Palmeira CM; Oliveira PJ; Ferreira, M.. "Bile acids are toxic for isolated cardiac mitochondria: a possible cause for hepatic-derived cardiomyopathies?". Cardiovascular toxicology 5 1 (2005): 63-73. http://europepmc.org/abstract/med/15738586. 10.1385/ct:5:1:063 Berthiaume, J.M.. "Dietary vitamin E decreases doxorubicin-induced oxidative stress without preventing mitochondrial dysfunction". Cardiovascular Toxicology 5 3 (2005): 257-267. http://www.scopus.com/inward/record.url?eid=2-s2.0-27144450968&partnerID=MN8TOARS. 10.1385/CT:5:3:257 Oliveira, P.J.. "Are the antioxidant properties of carvedilol important for the protection of cardiac mitochondria?". Current Vascular Pharmacology 3 2 (2005): 147-158. http://www.scopus.com/inward/record.url?eid=2-s2.0-18144430946&partnerID=MN8TOARS. 10.2174/1570161053586903 Ascensão, A.. "Moderate endurance training prevents doxorubicin-induced in vivo mitochondriopathy and reduces the development of cardiac apoptosis". American Journal of Physiology - Heart and Circulatory Physiology 289 2 58-2 (2005): http://www.scopus.com/inward/record.url?eid=2-s2.0-23744489541&partnerID=MN8TOARS. 10.1152/ajpheart.01249.2004 Oliveira PJ; Rolo AP; Sardão VA; Monteiro P; Gonçalves L; Providência LA; Palmeira CM; Moreno AJ; Oliveira, P.J.. "Advantages in the use of carvedilol versus propranolol for the protection of cardiac mitochondrial function.". Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 23 10 (2004): 1291-1298. http://europepmc.org/abstract/med/15641294. Oliveira, P.J.. "Vitamin E or coenzyme Q10 administration is not fully advantageous for heart mitochondrial function in diabetic goto kakizaki rats". Mitochondrion 3 6 (2004): 337-345. http://www.scopus.com/inward/record.url?eid=2-s2.0-1942484378&partnerID=MN8TOARS. 10.1016/j.mito.2004.02.005 Oliveira, P.J.. "Carvedilol-mediated antioxidant protection against doxorubicin-induced cardiac mitochondrial toxicity". Toxicology and Applied Pharmacology 200 2 (2004): 159-168. http://www.scopus.com/inward/record.url?eid=2-s2.0-5144227343&partnerID=MN8TOARS. 10.1016/j.taap.2004.04.005 Oliveira, P.J.. "Carvedilol Inhibits the Mitochondrial Permeability Transition by an Antioxidant Mechanism". Cardiovascular Toxicology 4 1 (2004): 11-20. http://www.scopus.com/inward/record.url?eid=2-s2.0-1942486470&partnerID=MN8TOARS. 10.1385/CT:4:1:11 Oliveira, P.J.. "Calcium-dependent mitochondrial permeability transition is augmented in the kidney of Goto-Kakizaki diabetic rat". Diabetes/Metabolism Research and Reviews 20 2 (2004): 131-136. http://www.scopus.com/inward/record.url?eid=2-s2.0-1842853998&partnerID=MN8TOARS. 10.1002/dmrr.423 Ferreira FM; Oliveira PJ; Rolo AP; Santos MS; Moreno AJ; da Cunha MF; Seiça R; Palmeira CM; Ferreira, F.M.. "Cholestasis induced by chronic treatment with alpha-naphthyl-isothiocyanate (ANIT) affects rat renal mitochondrial bioenergetics.". Archives of Toxicology 77 4 (2003): 194-200. http://europepmc.org/abstract/med/12698234. Monteiro P; Oliveira PJ; Gonçalves L; Providência LA. "Mitochondria: role in ischemia, reperfusion and cell death.". Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology (2003): http://europepmc.org/abstract/med/12769003. Oliveira PJ; Esteves T; Rolo AP; Monteiro P; Gonçalves L; Palmeira CM; Moreno AJ. "Carvedilol: relation between antioxidant activity and inhibition of the mitochondrial permeability transition.". Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology (2003): http://europepmc.org/abstract/med/12712810. Oliveira PJ; Rolo AP; Seiça R; Santos MS; Palmeira CM; Moreno AJ. "Chronic cholestasis and cardiac mitochondrial function in Wistar rats: a model for cardiovascular alterations in chronic liver disease?". Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology (2003): http://europepmc.org/abstract/med/12712811. Oliveira, P.J.. "Carvedilol: Relation between antioxidant activity and inhibition of the mitochondrial permeability transition \| Carvedilol: Relação entre a actividade antioxidante e inibição da transição de permeabilidade mitocondrial". Revista Portuguesa de Cardiologia 22 1 (2003): 55-62. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346034614&partnerID=MN8TOARS. Oliveira, P.J.; Oliveira PJ; Rolo AP; Seiça R; Santos MS; Palmeira CM; Moreno AJ. "Cardiac mitochondrial calcium loading capacity is severely affected after chronic cholestasis in Wistar rats". Journal of Investigative Medicine 51 2 (2003): 86-94. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037338705&partnerID=MN8TOARS. Monteiro, P.. "Pharmacological modulation of mitochondrial function during ischemia and reperfusion \| Modulação farmacológica da função mitocondrial no contexto da isquemia e reperfusão". Revista Portuguesa de Cardiologia 22 3 (2003): 407-429. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038795126&partnerID=MN8TOARS. Monteiro, P.. "Mitochondria: Role in ischemia, reperfusion and cell death \| Mitocôndrias: Que papel na isquémia, reperfusão e morte celular?". Revista Portuguesa de Cardiologia 22 2 (2003): 233-254. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037732545&partnerID=MN8TOARS. Palmeira, C.M.. "Histological changes and impairment of liver mitochondrial bioenergetics after long-term treatment with a-naphthyl-isothiocyanate (ANIT)". Toxicology 190 3 (2003): 185-196. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042133192&partnerID=MN8TOARS. 10.1016/S0300-483X(03)00163-X Oliveira, P.J.. "Enhanced permeability transition explains the reduced calcium uptake in cardiac mitochondria from streptozotocin-induced diabetic rats". FEBS Letters 554 3 (2003): 511-514. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242541631&partnerID=MN8TOARS. 10.1016/S0014-5793(03)01233-X Ferreira, F.M.. "Diabetes induces metabolic adaptations in rat liver mitochondria: Role of coenzyme Q and cardiolipin contents". Biochimica et Biophysica Acta - Molecular Basis of Disease 1639 2 (2003): 113-120. http://www.scopus.com/inward/record.url?eid=2-s2.0-0642345079&partnerID=MN8TOARS. 10.1016/j.bbadis.2003.08.001 Oliveira, P.J.. "Chronic cholestasis and cardiac mitochondrial function in wistar rats: A model for cardiovascular alterations in chronic liver disease? \| Colestase crónica e funçá~o mitocondrial cardíaca em ratos wistar: Um modelo para alterações cardiovasculares no contexto de doenças hepáticas crónicas?". Revista Portuguesa de Cardiologia 22 1 (2003): 67-75. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344951202&partnerID=MN8TOARS. Rolo, A.P.. "Chenodexycholate induction of mitochondrial permeability transition pore is associated with increased membrane fluidity and cytochrome c release: Protective role of carvedilol". Mitochondrion 2 4 (2003): 305-311. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037347309&partnerID=MN8TOARS. 10.1016/S1567-7249(03)00007-2 Oliveira, P.J.. "Reduction in cardiac mitochondrial calcium loading capacity is observable during a-naphthylisothiocyanate-induced acute cholestasis: A clue for hepatic-derived cardiomyopathies?". Biochimica et Biophysica Acta - Molecular Basis of Disease 1637 1 (2003): 39-45. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037454702&partnerID=MN8TOARS. 10.1016/S0925-4439(02)00212-0 Rolo, A.P.. "Protection against post-ischemic mitochondrial injury in rat liver by silymarin or TUDC". Hepatology Research 26 3 (2003): 217-224. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042167601&partnerID=MN8TOARS. 10.1016/S1386-6346(03)00108-6 Oliveira PJ; Rolo AP; Monteiro P; Gonçalves L; Palmeira CM; Moreno AJ. "Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase--what role in myocardial ischemia and reperfusion?". Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology (2002): http://europepmc.org/abstract/med/12621918. Oliveira PJ; Rolo AP; Seiça R; Sardão V; Monteiro P; Gonçalves L; Providência L; et al. "Impact of diabetes on induction of the mitochondrial permeability transition.". Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 21 6 (2002): 759-766. http://europepmc.org/abstract/med/12194377. Marques, M.P.M.. "Study of carvedilol by combined Raman spectroscopy and ab initio MO calculations". Journal of Raman Spectroscopy 33 10 (2002): 778-783. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036773098&partnerID=MN8TOARS. 10.1002/jrs.916 Rolo, A.P.. "Improved efficiency of hepatic mitochondrial function in rats with cholestasis induced by an acute dose of a-naphthylisothiocyanate". Toxicology and Applied Pharmacology 182 1 (2002): 20-26. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036070550&partnerID=MN8TOARS. 10.1006/taap.2002.9434 Oliveira, P.J.. "Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase - What role in myocardial ischemia and reperfusion? \| Impacto do carvedilol sobre o dano mitocondrial induzido por hipoxantina/xantina oxidase - Que papel na isquemia e reperfusão do miocárdio?". Revista Portuguesa de Cardiologia 21 12 (2002): 1447-1455. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036998602&partnerID=MN8TOARS. Rolo, A.P.; Rolo AP; Oliveira PJ; Seiça R; Santos MS; Moreno AJ; Palmeira CM. "Disruption of mitochondrial calcium homeostasis after chronic a-naphthylisothiocyanate administration: Relevance for cholestasis". Journal of Investigative Medicine 50 3 (2002): 193-200. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036092085&partnerID=MN8TOARS. Sardão, V.A.. "Caffeine enhances the calcium-dependent cardiac mitochondrial permeability transition: Relevance for caffeine toxicity". Toxicology and Applied Pharmacology 179 1 (2002): 50-56. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037082662&partnerID=MN8TOARS. 10.1006/taap.2001.9334 Rolo, A.P.. "Protective effect of carvedilol on chenodeoxycholate induction of the permeability transition pore". Biochemical Pharmacology 61 11 (2001): 1449-1454. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035370544&partnerID=MN8TOARS. 10.1016/S0006-2952(01)00620-7 Oliveira, P.J.. "Inhibitory effect of carvedilol in the high-conductance state of the mitochondrial permeability transition pore". European Journal of Pharmacology 412 3 (2001): 231-237. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035793307&partnerID=MN8TOARS. 10.1016/S0014-2999(01)00745-2 Oliveira, P.J.; Oliveira PJ; Rolo AP; Seiça R; Palmeira CM; Santos MS; Moreno AJ. "Decreased susceptibility of heart mitochondria from diabetic GK rats to mitochondrial permeability transition induced by calcium phosphate". Bioscience Reports 21 1 (2001): 45-53. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034905572&partnerID=MN8TOARS. 10.1023/a:1010482017540 Rolo, A.P.. "Chenodeoxycholate is a potent inducer of the permeability transition pore in rat liver mitochondria". Bioscience Reports 21 1 (2001): 73-80. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034899577&partnerID=MN8TOARS. 10.1023/A:1010438202519 Oliveira, P.J.. "Carvedilol reduces mitochondrial damage induced by hypoxanthine/xanthine oxidase: Relevance to hypoxia/reoxygenation injury". Cardiovascular Toxicology 1 3 (2001): 205-213. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035750084&partnerID=MN8TOARS. 10.1385/CT:1:3:205 Oliveira, P.J.. "Carvedilol in heart mitochondria - Protonophore or opener of the mitochondrial KATP channels?". Life Sciences 69 2 (2001): 123-132. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035371154&partnerID=MN8TOARS. 10.1016/S0024-3205(01)01109-2 Rolo AP; Oliveira PJ; Moreno AJ; Palmeira CM. "Bile acids affect liver mitochondrial bioenergetics: possible relevance for cholestasis therapy.". (2000): http://europepmc.org/abstract/med/10966524. 10.1093/toxsci/57.1.177 Oliveira, P.J.. "Carvedilol inhibits the exogenous NADH dehydrogenase in rat heart mitochondria". Archives of Biochemistry and Biophysics 374 2 (2000): 279-285. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034652094&partnerID=MN8TOARS. 10.1006/abbi.1999.1624 Oliveira, P.J.. "Effects of carvedilol on isolated heart mitochondria: Evidence for a protonophoretic mechanism". Biochemical and Biophysical Research Communications 276 1 (2000): 82-87. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034675219&partnerID=MN8TOARS. 10.1006/bbrc.2000.3374
Preprint	Teresa Cunha-Oliveira; Daniela Franco Silva; Luis Segura; Inês Baldeiras; Ricardo Marques; Tatiana Rosenstock; Paulo J. Oliveira; Filomena S.G. Silva. "Oxidative stress profiles of lymphoblasts from Amyotrophic Lateral Sclerosis patients with or without known SOD1 mutations". 2022. https://doi.org/10.1101/2022.03.03.482309. 10.1101/2022.03.03.482309

Intellectual property

Patent

Borges, Maria Fernanda; Oliveira, Paulo; Teixeira, José; Cagide-Fagin, Fernando; Oliveira, Ana Catarina. 2018. "HYDROXYBENZOIC DERIVATIVES, METHODS AND USES THEREOF".
Oliveira, Paulo; Teixeira, José; Cagide-Fagin, Fernando; Benfeito, Ester Sofia. 2018. "HYDROXYCINNAMIC DERIVATIVES, METHODS AND USES THEREOF (".

Other

Other output

Synthesis, Characterisation and Antiproliferative Studies of Allyl(dicarbonyl)(cyclopentadienyl)molybdenum Complexes and Cyclodextrin Inclusion Compounds. The complexes [(eta(5)-C5H4-CO-R)Mo(CO)(2)(eta(3)-C3H5)] [R = OH (1), Phe OMe (2)] have been examined as guests for the cyclodextrin (CD) hosts beta-CD and heptakis(2,3,6-tri-O-methyl)-beta-CD (TRIMEB), and the resultant inclusion compounds have been characterised in the solid state by elemental and thermogravimetric analyses, powder X-ray diffraction, C-13{H-1) cross-polarisation (CP) magic angle. 2014. Braga, Susana S.; Mokal, Vijaya; Almeida Paz, Filipe A.; Pillinger, Martyn; Branco, Ana F.; Sardao, Vilma A.; Diogo, Catia V.; et al. http://hdl.handle.net/10773/19837.
10.1002/ejic.201402540
Bile acids are toxic for isolated cardiac mitochondria. Abstract Cholestasis and other liver diseases may affect the heart through the toxic effects of the retained bile acids on cardiac mitochondria, which could explain the origin of hepatic-derived cardiomyopathies. The objective of this work was to test the hypothesis that bile acids are toxic to heart mitochondria for concentrations that are relevant for cholestasis. Heart mitochondria were isolate. 2005. Ferreira, Manuela; Coxito, Pedro; Sardão, Vilma; Palmeira, Carlos; Oliveira, Paulo. http://hdl.handle.net/10316/7824.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2021/12/02	A Story of Bad Livers	Valorizebyproducts Webinars Universidade de Trás-os-Montes e Alto Douro (Online, Portugal)
2021/10/29	A Mitochondria-Targeted Caffeic Acid Derivative Reverts Cellular and Mitochondrial Defects in Human Skin Fibroblasts from Male Sporadic Parkinson’s Disease Patients	Targeting Mitochondria Meeting World Mitochondria Society (online, Germany)
2021/06/09	Mitochondrial Determinants of Doxorubicin Cardiotoxicity	55th Annual meeting of the European Society for Clinical Investigation, “The Micro Me’s – Exploring microbiota in health and disease” European Society for Clinical Investigation (Online, Italy)
2021/05/07	Mitochondria as a Target in Drug Development	First webinar on Medicinal Chemistry – Designing Tomorrow’s Therapeutics online, organized by Dr. Fernanda Borges, University of Porto, Portugal (Online, Portugal)
2021/03/11	Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention	Redox Webinar Series - Oxidative Stress: Biochemical and Pharmacological Aspects (online) organized by Dr. Luciano Saso, Sapienza University of Rome, Italy (online, Italy)
2020/09/03	mtFOIE-GRAS Non-invasive Profiling of Mitochondrial Function in Non-Alcoholic Fatty Liver Disease	EuroScience Open Forum (ESOF) (Trieste, Italy)
2020/02/18	FOIE GRAS or A Story of Mitochondria and Fatty Livers	Escola Superior Agrária de Coimbra (ESAC) (Coimbra, Portugal)
2019/11/30	The Cellular Chi: Mitochondria as a Target for Natural and Artificial Compounds in Health and Disease	Sino-Portugal Forum on Traditional Medicine (Nanchang, China)
2019/11/10	Over and Under-nutrition During Pregnancy as a Remodeling Factor for Liver and Heart Fetal Mitochondria	International Workshop on Advances inAnalytical Methods for Monitoring Food Quality and Safety (Bratislava, Slovakia)
2019/09/18	Mitochondria, pluripotency and quality control in embryonal carcinoma cells	6th Conference on Mitochondria, Apoptosis and Cancer (MAC2019), Prague, Czech Republic (Praga, Czech Republic)
2019/09/06	Metabolism, Quality Control, and Pluripotency in Embryonal Carcinoma Cells	II FEBS Advanced Course on Oncometabolism (Luso, Portugal)
2019/07/16	MitoTAG: From Cellular Organelle to Idea to Start Up and Beyond	EIT Health InnoStars Bootcamp (Coimbra, Portugal)
2019/07/04	Improving Nature: Targeting Active Polyphenols to Mitochondria	XIV Annual CICS-UBI Meeting (Covilhã, Portugal)
2019/07/01	POWER-UP - Mitochondrial Biology and Follies, ETN Treatment Network School	University of Coimbra (Coimbra, Portugal)
2019/05/24	Disruption of Mitochondrial Metabolism and Circadian Genes by Anthracyclines	53rd Annual Meeting of the European Society for Clinical Investigation (Coimbra, Portugal)
2019/03/30	From a small organelle to a small start-up and beyond…,	Academica StartUC, University of Coimbra (Coimbra, Portugal)
2019/03/29	In utero Programing of Mitochondrial Function by Nutrition	TIFN Midterm Project Meeting (Wageningen, Netherlands)
2019/03/16	From Mitochondria to Business. The Example of MitoTAG	III Meet.Lab (Coimbra, Portugal)
2019/01/17	Mitochondria as a Pharmacological and Toxicological Target in Drug Development	International Iberian Nanothechnology Laboratory (Braga, Portugal)
2019/01/17	MitoTAG: From Bench to Business	International Iberian Nanothechnology Laboratory (Porto, Portugal)
2018/11/23	Implications of Mitochondrial Metabolism for Aging	Leonard Davies School of Gerontology, University of Southern California (Califórnia, United States)
2018/07/29	MitoTAG	EIT Health InnoStars Bootcamp (Coimbra, Portugal)
2018/07/13	Pluripotency, mitochondrial metabolism, and quality control mechanisms in embryonal carcinoma cells	MitoPORTO 2018 (Porto, Portugal)
2018/07/12	Identifying Mitochondrial Toxicity in Early Pre-Clinical Drug Development	VIII Meeting of the Paul Ehrlich Euro-PhD Network (Porto, Portugal)
2018/07/03	Understanding the Right and Wrong Metabolism in Lifestyle, Environment and Aging-related Diseases	Encontro Ciência 2018 (Lisboa, Portugal)
2018/06/04	Malnutrition vs calorie restriction: The effects of maternal nutrient reduction in cardiac fetal mitochondrial function	Bi-annual Meeting of the Society for Free Radical Research International (Lisboa, Portugal)
2018/05/30	Back to the Basics: Evolution of Mitochondrial Respirometry and Basic Concepts	52nd Annual Meeting of the European Society for Clinical Investigation (Barcelona, Spain)
2018/01/15	Metabolism and Pluripotency in Embryonal Carcinoma Stem Cells	ICVS - Life and Health Sciences Research Institute (Braga, Portugal)
2018/01/06	An Update on the ETN Project FOIE GRAS	52nd Annual Meeting of the European Society for Clinical Investigation (Barcelona, Spain)
2017/12/21	Sirtuin 1-dependent Resveratrol Cytotoxicity and Pro-differentiation Activity on Breast Cancer Cells	2nd Biomedical Meeting at UC, University of Coimbra (Coimbra, Portugal)
2017/12/08	Anthracycline-induced Cardiotoxicity: Tales from a Mitochondrial Journey	Meet Your Future Workshop, Gottingen Medical Center (Gottingen, Germany)
2017/11/21	Mitochondrial Alterations in Non-alcoholic Fatty Liver Disease: A Tale of (Bad) Nutrition and Batteries	Science and Technology Week 2017, University of Trás-os-Montes and Alto Douro (Vila Real, Portugal)
2017/09/22	Mitochondrial Toxicology in Drug Discovery and Development	EpiChemBio (CM1406) and MuTaLig (CA15135) COST actions joint meeting 2017 (Porto, Portugal)
2017/09/19	Mitochondria vs. Godzilla: In Search of Energy	Instituto Bissaya Barreto (Coimbra, Portugal)
2017/09/16	Mitochondrial Metabolism and Cellular Quality Control Regulate Differentiation in P19 Embryonal Carcinoma Stem Cells	Mitochondria, Apoptosis and Cancer, Bled (Slovenia)
2017/06/18	Targeting Mitochondria in Cancer	FEBS Advanced Course on Oncometabolism (Figueira da Foz, Portugal)
2017/05/17	Targeting Mitochondria with Improved Dietary Antioxidants	51st Annual Meeting of the European Society for Clinical Investigation (Genoa, Italy)
2017/05/17	ETN FOIE GRAS – the European Network	51st Annual Meeting of the European Society for Clinical Investigation (Genoa, Italy)
2017/03/05	Mitochondrial Dysfunction and Bioenergetic Collapse	ENEBT 2017 – National Meeting of Biotechnology Students, University of Aveiro (Aveiro, Portugal)
2017/03/04	Mitochondria vs. Godzilla Electric Circuits, Disease and Smart Missiles	IMeet.Lab, University of Coimbra (Coimbra, Portugal)
2017/02/16	Optimizing Nature: Targeting Mitochondria with Enhanced Natural Antioxidants	VIII Course Week, Agricultural School of Coimbra (Coimbra, Portugal)
2016/12/28	Portugal, um País Apetecível?	5th GraPE Meeting, University of Coimbra (Coimbra, Portugal)
2016/12/19	Heartbroken: Mitochondrial Damage by Anthracyclines	I Biomedical Meeting @UC, University of Coimbra (Coimbra, Portugal)
2016/11/02	Mitochondrial Folies: From Basic Science to Product Development	Innovation Now 2016! (Aveiro, Portugal)
2016/10/24	Optimizing Nature: Targeting Mitochondria with Enhanced Natural Antioxidants	Targeting Mitochondria (Berlim, Germany)
2016/10/19	Mitochondrial Remodeling During Embryonal Carcinoma Stem Cell Differentiation	CEDOC, Universidade NOVA de Lisboa
2016/06/29	Polyphenol toxicity and mitochondrial function: an emergent link	Porto Polyphenols Congress 2016 (Porto, Portugal)
2016/04/28	Mitochondrial TRAP1 in cancer metabolism and quality control	50th Annual Scientific Meeting of the European Society of Clinical Investigation (Paris, France)
2016/03/21	Remodeling Mitochondria During P19 Embryonal Carcinoma Cell Differentiation	IX National Meeting of the Biochemistry Students (Coimbra, Portugal)
2015/10/08	Remodeling Mitochondria During P19 Embryonal Carcinoma Cell Differentiation	Institute of Biotechnology CAS (Prague, Czech Republic)
2015/05/30	Anthracycline-induced Cardiac Mitochondrial Injury: Multiple Targets, Multiple Effects	49th Annual Scientific Meeting of the European Society of Clinical Investigation (Cluj, Romania)
2015/05/29	Exercising Mitochondria: Improving Mitochondrial Capacity by Physical Activity	49th Annual Scientific Meeting of the European Society of Clinical Investigation (Cluj, Romania)
2015/05/07	Mitochondrial and Metabolic Remodeling During P19 Embryonal Carcinoma Cell Differentiation	XXIII Porto Cancer Meeting (Porto, Portugal)
2015/02/22	Mitochondrial Phenotype in Cancer Cells	Give Science to Life Meeting (Coimbra, Portugal)
2015/02/21	Targeting Mitochondria in Tumor Cells	IN4Med Meeting (Coimbra, Portugal)
2015/02/07	Basic mechanisms for Anthracycline cardiotoxicity and therapeutic targets	Annual Meeting of the Study Group for Myocardium and Pericardium Diseases, Portuguese Cardiology Society (Óbidos, Portugal)
2014/11/21	30. Cellular Respiration as a Biomarker: Evolution of Technology	Integrating Biomarkers and Cell Physiology for Metabolic Profiling: Next Generation Approaches and Technologies Workshop, Biocant Park (Cantanhede, Portugal)
2014/11/21	Analysis of Cell Metabolism Using the Seahorse Extracellular Flux Analyzer – Principles and Applications	“Integrating Biomarkers and Cell Physiology for Metabolic Profiling: Next Generation Approaches and Technologies” Workshop, Biocant Park (Cantanhede, Portugal)
2014/05/14	Mitochondrial Degeneration During Aging: Causes and Solutions	5th Symposium of Health Sciences “Aging”, Medical School, University of Lisbon (Lisboa, Portugal)
2014/05/03	The Role of Mitochondria on Anthracycline-induced Cardiomyopathy	48th Annual Scientific Meeting of the European Society of Clinical Investigation (Utrecht, Netherlands)
2014/04/28	Triterpenoid Derivatives as Mitochondrial Disturbing Agents in Breast Cancer Cell Lines	Nencki Institute of Experimental Biology (Varsóvia, Poland)
2013/07/09	Mitochondria as a Perfect Target in Health and Disease	Department of Biology, University of Braga (Braga, Portugal)
2013/06/11	Doxorubicin-induced Cardiac Mitochondrionopathy: A Tale of Targets and Mechanism	CIAFEL, School of Sports and Physical Activity, University of Porto (Porto, Portugal)
2013/04/29	Mitochondria as a Tool in Drug Discovery	Natural Products: Health and Pharmaceutical Research Workshop, ESAC (Coimbra, Portugal)
2013/04/17	Targeting the Powerplants in Cancer	47th Annual Meeting of the European Society for Clinical Investigation (Albufeira, Portugal)
2013/01/27	In Vitro Models in Basic Research	International Conference of Alternatives to Animal Experimentation (Almada, Portugal)
2012/12/10	Alternatives to Animal Use in Toxicological Testing	Alternatives to Animal Use in Pre-Clinical Studies, ShareBiotech (Cantanhede, Portugal)
2012/11/25	Targeting Mitochondria in Cardiovascular Diseases and Cancer	Jornadas de Bioquímica, University of Coimbra (Coimbra, Portugal)
2012/11/08	19. Mitochondria as a Perfect Target in Health and Disease	Targeting Mitochondria Meeting (Berlim, Germany)
2012/10/25	Mitochondria and Polyphenols: a Tale of Mending Hearts	Flawopiryna” Conference, Medical University of Lodz (Lodz, Poland)
2012/07/10	Mitochondria as a Perfect Target in Health and Disease	Department of Biology, University of Braga (Braga, Portugal)
2012/03/31	Our Battery: What Keeps us Moving	IEC, Institute for Education and Citizenship (Mamarrosa, Portugal)
2012/03/29	Mitochondria in Health and Disease: a Tale of Injury and Redemption	University of Tras-os-Montes and Alto Douro (UTAD) (Vila Real, Portugal)
2012/03/24	Mitochondria: You Are what You Eat	45th Annual Scientific Meeting of the European Society for Clinical Research (Budapeste, Hungary)
2012/03/23	Berberine as a Potential Mitochondrial-directed Anti-cancer Agent	45th Annual Scientific Meeting of the European Society for Clinical Investigation (Budapeste, Hungary)
2012/02/22	Regulation of Mitochondrial Function by Exercise (joint research seminar/lecture for first year Medical Students)	University of Valencia Medical School (Valência, Spain)
2011/11/10	Mitochondrial Dynamics and Physiology During P19 Embryonal Cell Differentiation	University of Texas Health Science Center, CPNR Research Seminar (San Antonio, Texas, United States)
2011/11/09	Short-Circuit: Tales of Broken Mitochondria	University of Texas Health Science Center Ob/Gyn Grand Rounds Seminar (San Antonio, Texas, United States)
2011/06/08	Tales of Broken Mitochondria: Drug-induced Cardiac Mitochondrionopathy,	World Pharma Congress (Philadelphia, PA, United States)
2010/05/19	When Batteries Fail – Tales of Broken Mitochondria	CNC Seminar (Coimbra, Portugal)
2008/09/23	Anti-melanoma Effects of the Alkaloid Berberine - Role of Mitochondrial Interactions	University of Minnesota (Duluth, MN, United States)
2008/04/26	Mitochondrial Toxicology and Pharmacology	V National Meeting of Biochemistry Students (Coimbra, Portugal)
2006/11/03	Cardiac Mitochondrial Toxicity of Antineoplastic Agents	2006 CNC Seminars (Coimbra, Portugal)
2005/09/08	Cardiac Mitochondrial Alterations During Doxorubicin Treatment: Targets and Preventive Strategies	University of Colorado Health Sciences Center (Denver, United States)
2003/11/26	Mitochondrial Permeability Transition – Relevance for Toxicity and Pathology	Conferências de Bioquímica Vítor Madeira (Coimbra, Portugal)
2002/09/10	Critical Role of Mitochondrial Protein Thiol Groups in the Inhibitory Action of Carvedilol on the Mitochondrial Permeability Transition	12th European Bioenergetics Conference (EBEC) (Arcachon, France)
2002/03/20	Resistance to Myocardial Ischemia and Reperfusion – A Mitochondrial Determinant?	V Congresso Português de Diabetes (Vilamoura, Portugal)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2017 - Current	Mitochondria-directed Antioxidants as a Therapy for Non-Alcoholic Fatty Liver Disease Supervisor	Biologia Experimental e Biomedicina (PhD) Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2016 - Current	Urinary-derived Cells in Personalized Medicine: Role of Mitochondrial Metabolism Supervisor	Envelhecimento e Doenças Crónicas (PhD) Universidade de Coimbra Faculdade de Medicina, Portugal
2015 - Current	Development of Multitarget Directed Antioxidants with Therapeutic Potential Towards Age-related Disorders Supervisor	Ciências Farmacêuticas (PhD) Universidade do Porto Faculdade de Farmácia, Portugal
2015 - Current	Role of Mitochondria in Drosophila Tissue Repair Co-supervisor	Envelhecimento e Doenças Crónicas (PhD) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2015 - Current	An Innovative Metabolic and Epigenetic Engineering Approach to Reverse the Parkinson Disease Cell State Supervisor	Biologia Experimental e Biomedicina (PhD) Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2015 - Current	Neuroprotective Effects of Potent Antioxidant Molecules Isolated From Bifurcaria bifurcata and Codium tomentosum in an in vitro and in vivo Parkinson Disease Model Co-supervisor	Ciências Marinhas, Tecnologia e Gestão (PhD) Instituto Politécnico de Leiria, Portugal
2012 - Current	Menopause vs. Osteoporosis – The Role of Phytoestrogens on Bone Remodeling and their Antiosteoporetic Effects Co-supervisor	Biociências (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2011 - Current	Modulation of Heart and Skeletal Muscle Mitochondrial Sirtuin 3 by Acute Exercise and Endurance Training – Relevance for Exercise-induced Mitochondrial Adaptations Supervisor	Biociências Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2022 - 2022	CardioCLOCK: Descoberta de Mecanismos de Interações entre Programação durante o Desenvolvimento e Envelhecimento do Coração / CardioCLOCK: Unraveling Mechanisms of Developmental Programming-aging interactions in the heart Supervisor	Biologia Experimental e Biomedicina (PhD) Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2022 - 2022	Organelle-targeted Radioconjugates for Auger Therapy of Prostate Cancer Co-supervisor	Biologia Celular e Molecular (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015 - 2020	Molecular Mechanims of Mitochondrial Transfer from Stromal cells to cancer cells with damaged mitochondrial DNA Supervisor	Biologia Experimental e Biomedicina (PhD) Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2019 - 2019	Mitochondriotropic Antioxidants Based on Dietary Phenolic Acids as Modulators of Oxidative Stress on Skin Fibroblasts Supervisor	Biotecnologia Farmacêutica (Master) Universidade de Coimbra Faculdade de Farmácia, Portugal
2019 - 2019	MitoBULLET: Antioxidant Targeting of Mitochondria to Prevent Non-Alcoholic Fatty Liver Disease-induced Oxidative Stress Supervisor	Biologia Experimental e Biomedicina (PhD) Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2019 - 2019	Development of new chemical entities based on natural scaffolds with therapeutic potential towards age-related disorders. Supervisor	Ciências Farmacêuticas (PhD) Universidade do Porto Faculdade de Farmácia, Portugal
2017 - 2019	Role of Mitochondria-Targeted Novel Antioxidants based in Dietary Polyphenols Supervisor	Biotecnologia Farmacêutica (Master) Universidade de Coimbra Faculdade de Farmácia, Portugal
2015 - 2019	Targeting Hsp70 in Huntington's Disease Co-supervisor	Ciências Farmacêuticas Universidade do Porto, Portugal
2014 - 2019	Pathophysiology of Persistent Doxorubicin Cardiotoxicity: a Mitochondrial-epigenetics Link Supervisor	Ciências Farmacêuticas (PhD) Universidade de Coimbra Faculdade de Farmácia, Portugal
2018 - 2018	Fetal Liver Mitochondria Alterations in an Ovine Model of Maternal Obesity Supervisor	Biologia Celular e Molecular (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2016 - 2018	Fetal Liver Mitochondria Alterations in an Ovine Model of Maternal Obesity Supervisor	Biologia Celular e Molecular (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015 - 2018	Effect of Life-span Exercise Against Obesity-induced Brain Mitochondrial Dysfunction Co-supervisor	Metabolismo - Clínica e Experimentação (PhD) Universidade do Porto Faculdade de Medicina, Portugal
2016 - 2016	The role of mitochondria in Drosophila wound healing Co-supervisor	Envelhecimento e Doenças Crónicas (associação) (PhD) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2012 - 2016	Targeting Dietary Antioxidants to Mitochondria: Regulating Mitochondrial Radical Production and Redox Signaling to Improve Human Health Co-supervisor	Ciências Farmacêuticas (PhD) Universidade do Porto Faculdade de Farmácia, Portugal
2011 - 2016	Mechanisms of DNA Damage Detection and Repair in Embryonic Carcinoma Cells: A Model to Study Chemotherapy Resistance in Cancer Stem Cells Co-supervisor	Biociências (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009 - 2016	Programming of fetal cardio-renal mitochondria by maternal nutrition Supervisor	Biociências (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015 - 2015	Mitochondrial-directed antioxidants as anti-cancer agents Co-supervisor	Bioquímica (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015 - 2015	Doxorubicin cardiotoxicity: Metabolic landscaping of the epigenome Co-supervisor	Biologia Celular e Molecular (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013 - 2015	Mitochondria-directed Antioxidants as Anticancer Agents Supervisor	Bioquímica (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013 - 2015	Pathophysiology of Persistent Doxorubicin Cardiotoxicity: Metabolic Landscaping of the Epigenome Supervisor	Biologia Celular e Molecular (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013 - 2015	Role of Mitochondrial p66Shc in Nefazodone-induced Mitochondrial Toxicity on HepG2 Cells Supervisor	Biologia (Master) Universidade de Trás-os-Montes e Alto Douro, Portugal
2011 - 2015	Unraveling Cancer Metabolism Through Flux Analysis and Metabolic Engineering Co-supervisor	Biociências (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2011 - 2015	Clarification of the Mitochondrial Role in the Cardiotoxicity of Doxorubicin Using a Whole Heart Perfusion System – Impact of Different Doxorubicin Treatment Regimens Supervisor	Biociências (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014 - 2014	Berberine modulation on doxorubicin-induced cell death and autophagy Co-supervisor	Bioquímica (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014 - 2014	Cardiolipin content in P19 embryonal carcinoma cells Co-supervisor	Bioquímica (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2014 - 2014	Protection provided by phytoestrogens against cardiac lipotoxicity induced by palmitic acid Co-supervisor	Bioquímica (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012 - 2014	Role of Sirtuin 3 on Doxorubicin-induced Toxicity on H9c2 Cardiomyoblasts Supervisor	Biologia Celular e Molecular (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012 - 2014	Berberine Modulation on Doxorubicin-induced Cell Death and Autophagy Supervisor	Bioquímica (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012 - 2014	Protection Provided by Phytoestrogens Against Cardiac Lipotoxicity Induced by Palmitic Acid Supervisor	Bioquímica (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012 - 2014	Cardiolipin content in P19 embryonal carcinoma cells Supervisor	Bioquímica (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009 - 2014	TRAP1 Regulation of Mitochondrial Homeostasis and Cellular Quality Control Supervisor	Biologia (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009 - 2013	Oxidative Stress, Mitochondrial Dysfunction and Cellular pathology in Experimental Models of Hyperglycaemia and High Fat Diet Supervisor	Biologia (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009 - 2013	Idiosyncrasy of Drug-induced Mitochondrial Liabilities: From Mitochondrial DNA Single Nucleotide Polymorphisms to Mitochondrial Sirtuin Supervisor	Biologia (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008 - 2013	A Metabolic Switch for Cell Differentiation Co-supervisor	Biologia (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008 - 2013	Impact of H9c2 Cardiomyoblast Differentiation on Isoproterenol Toxicity: Different Modulation of Signaling Pathways Supervisor	Biologia Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008 - 2013	A Lipidomics Approach to Hepatic Mitochondrial Function and Toxicology: Role of Diet-induced Modifications Supervisor	Biociências (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2010 - 2012	Resveratrol and Cancer – What Role for Sirtuins? Supervisor	Biologia Aplicada (Master) Universidade de Aveiro, Portugal
2010 - 2012	Role of p66Shc Signaling on Doxorubicin-induced Cardiac Mitochondrial Dysfunction Supervisor	Biologia Celular e Molecular (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008 - 2012	Mitochondrial Physiology During Doxorubicin-induced Selective Cardiotoxicity Supervisor	Biociências (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009 - 2011	Dimethylaminopyridine Derivatives of Lupane Triterpenoids Acting as Mitochondrial-directed Agents on Breast Cancer Cells Supervisor	Biologia Celular e Molecular (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2011	Mitochondria and Cancer: Opening Pandora’s Box Supervisor	Biociências (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2011	Apoptosis Signaling as a Therapeutic Target in Melanoma Supervisor	Biologia Experimental e Biomedicina (PhD) Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2006 - 2011	Mitochondrial Function and Cell Death in Cardioplegic Preserved Hearts: Effects of Ischemia and Ischemia and Ischemia/Reperfusion Co-supervisor	Bioquímica (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2009	Mitochondrial and Cellular Toxicity of Two Triterpenoid Derivatives Supervisor	Biologia Celular e Molecular (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2009	In Vivo Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on Heart and Liver Mitochondrial Bioenergetics and ATP-sensitive Potassium Channels Supervisor	Biologia Celular e Molecular (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2009	Does Sub-Chronic Administration of Doxorubicin to Wistar Rats Result in Lung Apoptotic Signalling and Oxidative Stress? Supervisor	Biologia Celular e Molecular (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2006 - 2008	Cellular Alterations Involved in the Different Susceptibility of Differentiated and Non-differentiated H9c2 Myoblasts to Doxorubicin Supervisor	Biologia Celular e Molecular (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007 - 2007	A Lipidomic Approach to Hepatic Mitochondrial Function and Toxicology: role of Diet-Induced Modifications Co-supervisor	Biociências (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Event organisation

	Event name Type of event (Role)	Institution / Organization
2019/05/22 - 2019/05/24	Organizer of the 53rd Annual Meeting of the European Society for Clinical Investigation (2019/05/22 - 2019/05/24) Seminar (Co-organisor)	European Society for Clinical Investigation, Netherlands
2019/05/22 - 2019/05/24	Organization of Workshop “Mitochondrial Biology and Medicine”, part of the 53rd Annual Meeting of the European Society for Clinical Investigation (2019/05/22 - 2019/05/24) Symposium (Co-organisor)	European Society for Clinical Investigation, Netherlands
2018/10/23 - 2018/10/23	Organizer of Meeting “Mitochondrial DNA and Derived Peptides in Health and Disease” (2018/10/23 - 2018/10/23) Seminar (Co-organisor)	Universidade de Coimbra, Portugal
2018/05/30 - 2018/06/01	Organization of Workshop “Mitochondrial Biology and Medicine”, part of the 52rd Annual Meeting of the European Society of Clinical Investigation (2018/05/30 - 2018/06/01) Symposium (Co-organisor)	ESCI - European Society for Clinical Investigation, Netherlands
2017/05/17 - 2017/05/20	Organization of Workshop “Mitochondrial Biology and Medicine” (2017/05/17 - 2017/05/20) Symposium (Co-organisor)
2017/05/16 - 2017/05/16	Member of Scientific Commission, MitoPorto meeting (2017/05/16 - 2017/05/16) Seminar (Co-organisor)	Universidade do Porto, Portugal
2016/04/27 - 2016/04/29	Organization of Workshop “Mitochondrial Biology and Medicine” (2016/04/27 - 2016/04/29) Symposium (Co-organisor)	ESCI - European Society for Clinical Investigation, Netherlands
2015/05/27 - 2015/05/30	Organization of Workshop “Mitochondria: from Organelle to Patient”, (2015/05/27 - 2015/05/30) Symposium (Co-organisor)	European Society for Clinical Investigation, Netherlands
2015/02/02 - 2015/02/03	Chair of the Meeting “Cancer Epigenetics and Metabolism: Connecting the Dots”, (2015/02/02 - 2015/02/03) Seminar (Co-organisor)	Biocant Associação de Transferência de Tecnologia, Portugal
2014/11/21 - 2014/11/21	Co-organizer of the Workshop “Integrating Biomarkers and Cell Physiology for Metabolic Profiling: Next Generation Approaches and Technologies” (2014/11/21 - 2014/11/21) Symposium (Co-organisor)	Biocant Associação de Transferência de Tecnologia, Portugal
2014/04/28 - 2014/05/02	Organization of Workshop “Mitochondrial Translational Medicine”, part of the Annual Meeting of the European Society of Clinical Investigation (2014/04/28 - 2014/05/02) Symposium (Co-organisor)	European Society for Clinical Investigation, Netherlands
2013/04/17 - 2013/04/20	President of the Local Organization of the 47th Annual Meeting of the European Society for Clinical Investigation and Organization of the workshop “Mitochondrial Physiology: From Basic Research to the Clinic” (2013/04/17 - 2013/04/20) Seminar (Co-organisor)	European Society for Clinical Investigation, Netherlands
2012/03/22 - 2012/03/23	Organization of Workshop “Mitochondria in Health and Disease”, part of the Annual Meeting of the European Society of Clinical Investigation, Budapest (2012/03/22 - 2012/03/23) Symposium (Co-organisor)	ESCI - European Society for Clinical Investigation, Netherlands
2010/05/11 - 2010/05/14	Organization of the Meeting “Survival or Death as a Matter of Fat” (International Courses on Toxicology 2010) (2010/05/11 - 2010/05/14) Seminar (Co-organisor)	CNC.IBILI, Portugal
2009/05/05 - 2009/05/09	Organization of the Meeting “Mitochondria: Between Life and Death” (International Courses on Toxicology 2009) (2009/05/05 - 2009/05/09) Seminar (Co-organisor)	CNC.IBILI, Portugal
2008/04/09 - 2008/04/11	Organization of the Meeting “Metabolic Toxicology, From Pathway to Organism” (International Courses on Toxicology 2008) (2008/04/09 - 2008/04/11) Seminar (Co-organisor)	CNC.IBILI, Portugal
2007/03/21 - 2007/03/23	Organization of the Meeting “Stem cells as a Tool in Toxicology” (International Courses on Toxicology 2007) (2007/03/21 - 2007/03/23) Seminar (Co-organisor)	CNC.IBILI, Portugal
2006/03/22 - 2006/03/24	Organization of the Meeting “Smart Toxicology: Subcellular Targets of Anti-cancer Therapy” (International Courses on Toxicology 2006) (2006/03/22 - 2006/03/24) Seminar (Co-organisor)	CNC.IBILI, Portugal
2005/04/27 - 2005/04/29	Organization of the Meeting “Mitochondria: Between Life and Death” (International Courses on Toxicology 2005) (2005/04/27 - 2005/04/29) Seminar (Co-organisor)	CNC.IBILI, Portugal

Ad Hoc journal article review

	Journal title (ISSN)	Publisher
2019/05/01 - Current	Section Editor - European Journal of Clinical Investigation	Wiley
2004/12/01 - Current	Reviewer adhoc in more than 30 scientific journals including Aging, AJP, BBA, FASEB Journal, Nature Protocols, Circulation Research

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2023/03/04 - 2023/03/31	Molecular Biology of Cancer	Biologia Celular e Molecular (Mestrado)	Universidade de Coimbra Departamento de Ciências da Vida, Portugal

Journal scientific committee

	Journal title (ISSN)	Publisher
2000/01/01 - Current	Acta Physiologica
2000/01/01 - Current	American Journal of Anatomy and Physiology
2000/01/01 - Current	Biochemical Pharmacology (0006-2952)	Elsevier
2000/01/01 - Current	Biochemical Journal (1470-8728)	Portland Press
2000/01/01 - Current	Biochimica et Biophysica Acta (BBA) - Bioenergetics (0005-2728)	Elsevier
2000/01/01 - Current	BMC Cancer (1471-2407)	Springer (Biomed Central Ltd.)
2000/01/01 - Current	British Journal of Pharmacology (1476-5381)	Wiley (Blackwell Publishing)
2000/01/01 - Current	British Journal of Sports Medicine (1473-0480)	BMJ
2000/01/01 - Current	Cancer Biology & Therapy (1555-8576)	Landes Bioscience
2000/01/01 - Current	Cardiovascular Toxicology (1530-7905)	Springer-Verlag
2000/01/01 - Current	Cell Biology and Toxicology (1573-6822)	Springer-Verlag
2000/01/01 - Current	Cell Death and Disease (2041-4889)	Springer Science and Business Media LLC
2000/01/01 - Current	Environmental Chemistry Letters (1610-3661)	Springer-Verlag
2000/01/01 - Current	Environmental Technology (1479-487X)	Informa UK (Taylor & Francis)
2000/01/01 - Current	Epigenetics (1559-2308)	Landes Bioscience
2000/01/01 - Current	European Journal of Applied Physiology (1439-6327)	Springer-Verlag
2000/01/01 - Current	European Journal of Clinical Investigation (1365-2362)	Wiley (Blackwell Publishing)
2000/01/01 - Current	Journal of Cellular and Molecular Medicine (1582-4934)	Wiley (Blackwell Publishing)
2000/01/01 - Current	Expert Review of Molecular Diagnostics (1744-8352)	Informa UK (Taylor & Francis)
2000/01/01 - Current	Experimental Biology and Medicine (1535-3699)	SAGE Publications
2000/01/01 - Current	FEBS Letters (1873-3468)	Wiley (John Wiley & Sons)
2000/01/01 - Current	Free Radical Research (1029-2470)	Informa UK (Taylor & Francis)
2000/01/01 - Current	Frontiers in Bioscience (1093-4715)	Frontiers in BioScience
2000/01/01 - Current	International Journal of Cardiology (0167-5273)	Elsevier
2000/01/01 - Current	Journal of Applied Physiology (1522-1601)	American Physiological Society
2000/01/01 - Current	Journal of Cachexia Sarcopenia and Muscle (2190-6009)	Wiley (John Wiley & Sons)
2000/01/01 - Current	Journal of Experimental & Clinical Cancer Research (1756-9966)	Springer (Biomed Central Ltd.)
2000/01/01 - Current	The journal of nutrition health & aging (1760-4788)	Springer-Verlag
2000/01/01 - Current	Journal of Pharmacy and Pharmacology (2042-7158)	Wiley (Blackwell Publishing)
2000/01/01 - Current	The Journal of Physiology (1469-7793)	Wiley (Blackwell Publishing)
2000/01/01 - Current	Mitochondrion (1567-7249)	Elsevier
2000/01/01 - Current	Molecular Pharmacology (1521-0111)	American Society for Pharmacology & Experimental Therapeutics
2000/01/01 - Current	Nature Protocols (1754-2189)	Springer Science and Business Media LLC
2000/01/01 - Current	Nutrients (2072-6643)	MDPI AG
2000/01/01 - Current	Physiological Genomics (1531-2267)	American Physiological Society
2000/01/01 - Current	PLoS ONE (1932-6203)	Public Library of Science
2000/01/01 - Current	Scientific Reports (2045-2322)	Springer Science and Business Media LLC
2000/01/01 - Current	Trends in Molecular Medicine (1471-4914)	Elsevier
2000/01/01 - Current	Toxicology in Vitro (0887-2333)	Elsevier
2000/01/01 - Current	Toxicological Sciences (1096-0929)	Oxford University Press
2000/01/01 - Current	Toxicology and Applied Pharmacology (1096-0333)	Elsevier
2000 - Current	Frontiers in Oncology

Distinctions

Award

2022	Prize for Best Oral Presentation
2021	Poster Award (Senior Author) Sociedade Portuguesa de Diabetes, Portugal
2021	Poster Award (co-author) International Society of Microbiota, France
2020	Poster Award (senior author) European Society for Clinical Investigation, Netherlands
2020	Poster Award (senior author) ESCI - European Society for Clinical Investigation, Netherlands
2020	Poster Award (co-author) ESCI - European Society for Clinical Investigation, Netherlands
2020	Poster Award (senior author) ESCI - European Society for Clinical Investigation, Netherlands
2020	Poster Award (senior author) ESCI - European Society for Clinical Investigation, Netherlands
2020	Poster Award (senior author) European Society for Clinical Investigation, Netherlands

Other distinction

2019	Poster Award (senior author) SRI - Society for Reproductive Investigation, United States
2018	FLAD Healthcare 2020 Fundação Luso-Americana, Portugal
2018	Best Oral Talk (senior author) Sociedade Portuguesa de Diabetes, Portugal
2018	Poster Award (senior author) European Society for Clinical Investigation, Netherlands
2018	Poster Award (co-author) European Society for Clinical Investigation, Netherlands
2018	Poster Award (senior author) European Society for Clinical Investigation, Netherlands
2015	Senior author of Poster Award at the 49th Annual Meeting of the European Society for Clinical Investigation, Cluj-Napoca, Romania. “New Paradigms in Anticancer Combined Therapy: Targeting Dietary Antioxidants to Mitochondria” (Kátia Santos) European Society for Clinical Investigation, Netherlands
2014	Poster Award at the 48th Annual Scientific Meeting of the European Society for Clinical Investigation, “Physical Exercise Modulates Brain Cortex and Cerebellum Mitochondrial OXPHOS, Redox Status, Apoptotic Signaling, Mitochondrial Dynamics and Auto(mito)p European Society for Clinical Investigation, Netherlands
2014	Co-author of Young Research Award communication at the Asia Pacific Lung Cancer Congress 2014, “Metabolic Coupling in Lung Cancer Cell Lines by 13C NMR isotopomer Analysis” (Ludgero C. Tavares) International Association for the Study of Lung Cancer, United States
2004	Best Young Researcher in Basic Investigation Sociedade Portuguesa de Cardiologia, Portugal
2003	Best Young Researcher in Basic Investigation Prize (co-author) Sociedade Portuguesa de Cardiologia, Portugal
2003	Prize Aventis for Scientific Research (co-author) Sanofi Spa, Italy
1999	Prize for Merit
1998	Prize for Merit
1997	Prize for Merit