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Identification

Personal identification

Full name
Ana Rita Félix

Citation names

  • Félix, Rita

Author identifiers

Ciência ID
E31F-3A88-43A8
ORCID iD
0000-0001-7192-0822

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2019/01/01 - 2023/01/01
Ongoing
 Doutoramento em Farmácia (Doutoramento)
Major in Química Farmacêutica e Terapêutica
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2015
Concluded
 Master's degree in Chemistry (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Synthesis of New Chiral Organocatalysts for Asymmetric Reactions" (THESIS/DISSERTATION)
 16
2013
Concluded
 Bachelor’s degree in Chemistry (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Synthesis of Phthalocyanines for Carbon Dioxide Capture" (THESIS/DISSERTATION)
 14
Affiliation

Others

Category
Host institution 		Employer
2019/01/01 - Current Bolseiro de Doutoramento Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2019/01 - Current Bolseiro de Doutoramento Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2018/04/02 - Current Research Fellow “POINT4PAC: Oncologia de Precisão: Terapias e Tecnologias Inovadoras" (LISBOA-01-0145-FEDER-015405 – SAICTPAC/0019/2015) Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2017/01/01 - 2018/04/01 Research Fellow “ProbeCOPD: Activity-Based Probes as chemical tools for Chronic Obstructive Pulmonary Disease biomarker discovery” PTDC/BBB-BEP/ 2463/2014 iMed.ULisboa, Faculty of Pharmacy, Universi Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2015/12/01 - 2016/05/01 Trainee Extracurricular Internship Theoretical Chemistry Group Universidade de Coimbra Centro de Química de Coimbra, Portugal
Outputs

Publications

Conference poster
  1. Félix, Rita; Ana Mallo-Abreu; Rui Moreira. Corresponding author: Félix, Rita. "Novel Biochemical Tools to Analyse Resistance to Antibiotics Through a New qABP Approach". Paper presented in 8th EFMC Young Medicinal Chemists Symposium, 2021.
  2. Félix, Ana. "ß-lactam-derived quenched activity-based probes to analyse serine hydrolases". Paper presented in Congreso de Jóvenes Químicos y Bioquímicos Terapéuticos, IV QuimBioQuim, 2019.
  3. Félix, Ana. "Exploring quenching Activity-Based Probes (qABP) to detect ß-lactamases in biological matrices". Paper presented in 11th iMed.ULisboa Postgraduate Students Meeting & 4rd i3DU Meeting, 2019.
  4. Félix, Ana. "Optimization of neutrophil-elastase inhibitors as anti-inflammatory agents". Paper presented in 4rd meeting of Colégio de Química da Universidade de Lisboa - Chemistry: Shaping the Future, 2019.
  5. Félix, Ana. "Synthesis of asymmetric 1,3-diazetidinediones as inhibitors of HNE to target COPD". Paper presented in XXV ENCONTRO NACIONAL DA SPQ – Universidade de Lisboa, 2017, 2017.
  6. Félix, Ana. "New thiazolidine-based organocatalysts for enantioselective catalysis". Paper presented in XXIV ENCONTRO NACIONAL DA SPQ - University of Coimbra, 2015.
Journal article
  1. Rita Capela; Rita Félix; Marta Clariano; Diogo Nunes; Maria de Jesus Perry; Francisca Lopes. "Target Identification in Anti-Tuberculosis Drug Discovery". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms241310482.
    10.3390/ijms241310482
  2. Rocha, Susana; Félix, Rita; Valente, Maria João; Bento-Silva, Andreia; Rebelo, Rute; Amorim, Célia Gomes; Araújo, Alberto da Nova; et al. "Polysulfone Membranes Doped with Human Neutrophil Elastase Inhibitors: Assessment of Bioactivity and Biocompatibility". Membranes (2023): https://www.mdpi.com/2077-0375/13/1/89.
    10.3390/membranes13010089
  3. Luís A. R. Carvalho; Breyan Ross; Lorenz Fehr; Oguz Bolgi; Svenja Wöhrle; Kenneth M. Lum; David Podlesainski; et al. "Chemoproteomik-basierte Identifikation von 4-Oxo-ß-lactamen als Inhibitoren der Dipeptidylpeptidasen 8 und 9". Angewandte Chemie (2022): https://doi.org/10.1002/ange.202210498.
    10.1002/ange.202210498
  4. Luís A. R. Carvalho; Breyan Ross; Lorenz Fehr; Oguz Bolgi; Svenja Wöhrle; Kenneth M. Lum; David Podlesainski; et al. "Chemoproteomics-Enabled Identification of 4-Oxo-ß-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9". Angewandte Chemie International Edition (2022): https://doi.org/10.1002/anie.202210498.
    10.1002/anie.202210498
  5. Luís A. R. Carvalho; Breyan Ross; Lorenz Fehr; Oguz Bolgi; Svenja Wöhrle; Kenneth M. Lum; David Podlesainski; et al. "Titelbild: Chemoproteomik-basierte Identifikation von 4-Oxo-ß-lactamen als Inhibitoren der Dipeptidylpeptidasen 8 und 9 (Angew. Chem. 47/2022)". Angewandte Chemie (2022): https://doi.org/10.1002/ange.202213804.
    10.1002/ange.202213804
  6. Luís A. R. Carvalho; Breyan Ross; Lorenz Fehr; Oguz Bolgi; Svenja Wöhrle; Kenneth M. Lum; David Podlesainski; et al. "Cover Picture: Chemoproteomics-Enabled Identification of 4-Oxo-ß-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9 (Angew. Chem. Int. Ed. 47/2022)". Angewandte Chemie International Edition (2022): https://doi.org/10.1002/anie.202213804.
    10.1002/anie.202213804
  7. Félix, Ana. "Novel and Modified Neutrophil Elastase Inhibitor Loaded in Topical Formulations for Psoriasis Management". Pharmaceutics 12 (2020): 358-376. 10.3390/pharmaceutics12040358.
    Published
  8. Nunes, Andreia; Marto, Joana; Goncalves, Lidia Maria; Simoes, Sandra; Felix, Rita; Ascenso, Andreia; Lopes, Francisca; Ribeiro, Helena Margarida. "Novel and Modified Neutrophil Elastase Inhibitor Loaded in Topical Formulations for Psoriasis Management". Pharmaceutics (2020): https://publons.com/wos-op/publon/30763244/.
    10.3390/PHARMACEUTICS12040358
  9. Félix, Ana Rita G.; Simões, Pedro R. D.; Sousa, Francisco J. P. M.; Serra, M. Elisa Silva; Murtinho, Dina. "Chiral thiazolidine based organocatalysts: synthesis and application in asymmetric aldol reactions". Letters in Organic Chemistry 17 5 (2019): 372-380. http://dx.doi.org/10.2174/2210681209666190807155816.
    Published • 10.2174/2210681209666190807155816
  10. Félix, Ana. "Starch nanocapsules containing a novel neutrophil elastase inhibitor with improved pharmaceutical performance". European Journal of Pharmaceutics and Biopharmaceutics 127 (2018): 1-11. http://www.sciencedirect.com/science/article/pii/S0939641117313206.
    https://doi.org/10.1016/j.ejpb.2018.01.011
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/11 ß-Phospholactams as a novel chemical tool to target serine hydrolases XXVI Encontro Galego-Portugués de Química – November 2022
Sociedade Espanhola de Química e Sociedade Portuguesa de Química (Santiago de Compostela, Spain)
2023/07 “Design of Activity-Based Probes of Four-Membered Ring to Target Serine Hydrolases” 5º Encontro CQUL – “Chemistry: Forging bonds & Summer School” – July 2022
University of Lisbon (Lisboa, Portugal)
2022/07 Expanding the Toolbox of Four-Membered Ring Activity-Based Probes to Target Serine Hydrolases European School of Medicinal Chemistry ESMEC
University of Urbino (Urbino, Italy)
2021/09 Quenched Activity-Based Probes as New Chemical Tools to Analyse Serine Hydrolases XXVI EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC 2021)
European Federation for Medicinal Chemistry and Chemical Biology (EFMC)
2021/07/15 Quenched Activity Based Probes a s New Biochemical Tools to Analyse Resistance to Antibiotics XXVII ENSPQ - National Meeting of the Portuguese Chemical Society
Universidade do Minho
2021/04 Quenched activity-based probes as new chemical tools to analyse serine hydrolases ECHC - XXIX European Colloquium on HETEROCYCLIC CHEMISTRY
University of Rouen, COBRA-IRCOF, Rouen, France

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2021/06/16 - 2021/07/07 iMed.ULisboa Meeting 2021 (2021/06/16 - 2021/07/07)
Conference (Co-organisor)
 Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2012/09 - 2013/05 1º Encontro Nacional de Estudantes de Química (2013/03/22 - 2013/03/24)
Meeting (Co-organisor)
 Universidade de Coimbra, Portugal
Distinctions

Other distinction

2009 3% Melhores Alunos no ano lectivo 2009/2010
Universidade de Coimbra, Portugal