Personal identification

Full name

Ana Rita Gomes Félix

Citation names

• Félix, Rita

Author identifiers

Ciência ID

E31F-3A88-43A8

ORCID iD

0000-0001-7192-0822

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
French	Beginner (A1)	Beginner (A1)	Beginner (A1)	Beginner (A1)
Spanish; Castilian	Beginner (A1)	Beginner (A1)	Beginner (A1)	Beginner (A1)

	Degree	Classification
2019/01/01 - 2024/12/05 Concluded	PhD in Pharmacy (Doutoramento) Major in Pharmaceutical and Therapeutic Chemistry Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal "EXPANDING THE TOOLBOX OF FOUR-MEMBERED RINGS TO STUDY SERINE HYDROLASES" (THESIS/DISSERTATION)
2015 Concluded	Master's degree in Chemistry (Mestrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Synthesis of New Chiral Organocatalysts for Asymmetric Reactions" (THESIS/DISSERTATION)	16
2013 Concluded	Bachelor’s degree in Chemistry (Licenciatura) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Synthesis of Phthalocyanines for Carbon Dioxide Capture" (THESIS/DISSERTATION)	14

Others

	Category Host institution	Employer
2025/01/15 - Current	Postdoctoral researcher- "Ferrous Iron-Activable Drug Conjugates: Targeting Iron Metabolism in the Era of Precision Oncology"	Associação da Faculdade de Farmácia para a Investigação e Desenvolvimento, Portugal
	Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2024/09/10 - 2024/12/11	Research Fellow "Ferrous Iron-Activable Drug Conjugates: Targeting Iron Metabolism in the Era of Precision Oncology"	Universidade de Lisboa Faculdade de Farmácia, Portugal
	Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2019/01/01 - 2023/05/30	PhD Fellow - SFRH/BD/137459/2018 and COVID/BD/153228/2023.	Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
	Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal (...)
2018/04/02 - 2018/12/31	Research Fellow “POINT4PAC: Oncologia de Precisão: Terapias e Tecnologias Inovadoras" (LISBOA-01-0145-FEDER-015405 – SAICTPAC/0019/2015)	Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2017/01/01 - 2018/04/01	Research Fellow “ProbeCOPD: Activity-Based Probes as chemical tools for Chronic Obstructive Pulmonary Disease biomarker discovery” PTDC/BBB-BEP/ 2463/2014 iMed.ULisboa, Faculty of Pharmacy, Universi	Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2015/12/01 - 2016/05/01	Trainee Extracurricular Internship Theoretical Chemistry Group	Universidade de Coimbra Centro de Química de Coimbra, Portugal

Grant

	Designation	Funders
2023/03/01 - 2023/05/31	Expanding the Toolbox of Four-Membered Rings to Study Bacterial Serine Hydrolases COVID/BD/153228/2023 Universidade de Lisboa Faculdade de Farmácia, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2019/01/01 - 2022/12/31	Expanding the Toolbox of Four-Membered Rings to Study Bacterial Serine Hydrolases SFRH/BD/137459/2018 Universidade de Lisboa Faculdade de Farmácia, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Contract

	Designation	Funders
2023/01/01 - 2025/12/31	Conjugados de Fármacos Ativaveis por Ião Ferroso: Alvejar o Metabolismo do Ferro na Era da Oncologia de Precisão 2022.07857.PTDC 10.54499/2022.07857.PTDC	Fundação para a Ciência e a Tecnologia Ongoing

Publications

Conference poster

Félix, Rita; Ana Mallo-Abreu; Rui Moreira. Corresponding author: Félix, Rita. "Novel Biochemical Tools to Analyse Resistance to Antibiotics Through a New qABP Approach". Paper presented in 8th EFMC Young Medicinal Chemists Symposium, 2021. Félix, Rita. "ß-lactam-derived quenched activity-based probes to analyse serine hydrolases". Paper presented in Congreso de Jóvenes Químicos y Bioquímicos Terapéuticos, IV QuimBioQuim, 2019. Félix, Rita. "Exploring quenching Activity-Based Probes (qABP) to detect ß-lactamases in biological matrices". Paper presented in 11th iMed.ULisboa Postgraduate Students Meeting & 4rd i3DU Meeting, 2019. Félix, Rita. "Optimization of neutrophil-elastase inhibitors as anti-inflammatory agents". Paper presented in 4rd meeting of Colégio de Química da Universidade de Lisboa - Chemistry: Shaping the Future, 2019. Félix, Rita. "Synthesis of asymmetric 1,3-diazetidinediones as inhibitors of HNE to target COPD". Paper presented in XXV ENCONTRO NACIONAL DA SPQ – Universidade de Lisboa, 2017, 2017. Félix, Ana. "New thiazolidine-based organocatalysts for enantioselective catalysis". Paper presented in XXIV ENCONTRO NACIONAL DA SPQ - University of Coimbra, 2015.

Journal article

Rita Capela; Rita Félix; Marta Clariano; Diogo Nunes; Maria de Jesus Perry; Francisca Lopes. "Target Identification in Anti-Tuberculosis Drug Discovery". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms241310482. 10.3390/ijms241310482 Rocha, Susana; Félix, Rita; Valente, Maria João; Bento-Silva, Andreia; Rebelo, Rute; Amorim, Célia Gomes; Araújo, Alberto da Nova; et al. "Polysulfone Membranes Doped with Human Neutrophil Elastase Inhibitors: Assessment of Bioactivity and Biocompatibility". Membranes (2023): https://www.mdpi.com/2077-0375/13/1/89. 10.3390/membranes13010089 Luís A. R. Carvalho; Breyan Ross; Lorenz Fehr; Oguz Bolgi; Svenja Wöhrle; Kenneth M. Lum; David Podlesainski; et al. "Chemoproteomik-basierte Identifikation von 4-Oxo-ß-lactamen als Inhibitoren der Dipeptidylpeptidasen 8 und 9". Angewandte Chemie (2022): https://doi.org/10.1002/ange.202210498. 10.1002/ange.202210498 Luís A. R. Carvalho; Breyan Ross; Lorenz Fehr; Oguz Bolgi; Svenja Wöhrle; Kenneth M. Lum; David Podlesainski; et al. "Chemoproteomics-Enabled Identification of 4-Oxo-ß-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9". Angewandte Chemie International Edition (2022): https://doi.org/10.1002/anie.202210498. 10.1002/anie.202210498 Luís A. R. Carvalho; Breyan Ross; Lorenz Fehr; Oguz Bolgi; Svenja Wöhrle; Kenneth M. Lum; David Podlesainski; et al. "Titelbild: Chemoproteomik-basierte Identifikation von 4-Oxo-ß-lactamen als Inhibitoren der Dipeptidylpeptidasen 8 und 9 (Angew. Chem. 47/2022)". Angewandte Chemie (2022): https://doi.org/10.1002/ange.202213804. 10.1002/ange.202213804 Luís A. R. Carvalho; Breyan Ross; Lorenz Fehr; Oguz Bolgi; Svenja Wöhrle; Kenneth M. Lum; David Podlesainski; et al. "Cover Picture: Chemoproteomics-Enabled Identification of 4-Oxo-ß-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9 (Angew. Chem. Int. Ed. 47/2022)". Angewandte Chemie International Edition (2022): https://doi.org/10.1002/anie.202213804. 10.1002/anie.202213804 Nunes, Andreia; Marto, Joana; Goncalves, Lidia Maria; Simoes, Sandra; Felix, Rita; Ascenso, Andreia; Lopes, Francisca; Ribeiro, Helena Margarida. "Novel and Modified Neutrophil Elastase Inhibitor Loaded in Topical Formulations for Psoriasis Management". Pharmaceutics (2020): https://doi.org/10.3390/pharmaceutics12040358. 10.3390/PHARMACEUTICS12040358 Félix, Ana Rita G.; Simões, Pedro R. D.; Sousa, Francisco J. P. M.; Serra, M. Elisa Silva; Murtinho, Dina. "Chiral thiazolidine based organocatalysts: synthesis and application in asymmetric aldol reactions". Letters in Organic Chemistry 17 5 (2019): 372-380. http://dx.doi.org/10.2174/2210681209666190807155816. Published • 10.2174/2210681209666190807155816 Marto, J.; Ruivo, E.; Lucas, S.D.; Gonçalves, L.M.; Simões, S.; Gouveia, L.F.; Felix, R.; et al. "Starch nanocapsules containing a novel neutrophil elastase inhibitor with improved pharmaceutical performance". European Journal of Pharmaceutics and Biopharmaceutics 127 (2018): 1-11. https://doi.org/10.1016/j.ejpb.2018.01.011. 10.1016/j.ejpb.2018.01.011

Other distinction

2009	3% Melhores Alunos no ano lectivo 2009/2010 Universidade de Coimbra, Portugal