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Tiago André Coutinho Morais. Completed the Mestrado integrado in Toxicologia Analítica Clínica e Forense in 2010/12/31 by Universidade do Porto Faculdade de Farmacia and Licenciatura in Bioquímica in 2008/09/30 by Universidade do Porto Faculdade de Ciencias. Is Researcher in Universidade do Porto Unidade Multidisciplinar de Investigacao Biomedica. Published 17 articles in journals. Has received 4 awards and/or honors. Works in the area(s) of Medical and Health Sciences with emphasis on Health Sciences, Medical and Health Sciences with emphasis on Basic Medicine with emphasis on Toxicology and Natural sciences with emphasis on Biological Sciences with emphasis on Biochemistry. In their professional activities interacted with 71 collaborator(s) co-authorship of scientific papers.
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Identification

Personal identification

Full name
Tiago André Nogueira Coutinho Morais

Citation names

  • Morais, Tiago

Author identifiers

Ciência ID
E212-E90C-58A1
ORCID iD
0000-0003-4905-706X

Email addresses

  • tiagoacmorais@gmail.com (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Health Sciences
  • Medical and Health Sciences - Basic Medicine - Toxicology
  • Natural sciences - Biological Sciences - Biochemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Spanish; Castilian Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2017/01 - 2024/10/22
Concluded
 Ciências Biomédicas (Doutoramento)
Universidade do Porto Instituto de Ciencias Biomedicas Abel Salazar, Portugal
"Epigenetic & metabolic insights into the molecular crosstalk of obesity and dysglycemia" (THESIS/DISSERTATION)
2008/10/01 - 2010/12/31
Concluded
 Toxicologia Analítica Clínica e Forense (Mestrado integrado)
Universidade do Porto Faculdade de Farmacia, Portugal
"Perfil de distribuição no rato de nanopartículas de ouro com diferentes revestimentos" (THESIS/DISSERTATION)
 17
2003/09/01 - 2008/09/30
Concluded
 Bioquímica (Licenciatura)
Universidade do Porto Faculdade de Ciencias, Portugal
"Redução da actividade tónica dos receptores A2A na transmissão neuromuscular em animais com miastenia gravis induzida pela a-bungarotoxina:Interacção com autoreceptors colinérgicos com canais CaV2.1" (THESIS/DISSERTATION)
 13
Affiliation

Science

Category
Host institution 		Employer
2013/05/01 - Current Researcher (Research) Universidade do Porto Unidade Multidisciplinar de Investigacao Biomedica, Portugal
Projects

Grant

Designation Funders
2018/10 - 2022/09 Exploring the role of epigenomic and adipocyte-associated signals in metabolic dysfunction
Provided by PTCRIS: PTDC/MEC-MET/32151/2017
 Fundação para a Ciência e a Tecnologia

Contract

Designation Funders
2011/01/01 - 2012/12/31 Strategic Project - LA 6 - 2011-2012
PEst-C/EQB/LA0006/2011
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Conference abstract
  1. Morais, Tiago; Seabra, Alexandre; Patrício, Bárbara G; Guimarães, Marta; Nora, Mário; Oliveira, Pedro F.; Alves, Marco G.; Monteiro, Mariana P.. "O perfil metabólico do tecido adiposo visceral varia de acordo com o IMC e status glicémico.". Paper presented in 16º Congresso Português de Diabetes, 2020.
Conference paper
  1. Martins, Ana D; Jarak, Ivana; Morais, Tiago; Carvalho, Rui A; Oliveira, Pedro F.; Monteiro, Mariana P; Alves, Marco G.. "Caloric restriction alters the hormonal profile and testicular metabolome resulting in sperm head defects in Wistar rats". Paper presented in SEHIT 2019, 2019.
Conference poster
  1. Morais, Tiago; Seabra, Alexandre; Patrício, Bárbara G; Guimarães, Marta; Nora, Mário; Oliveira, Pedro F; Alves, Marco G; Monteiro, Mariana P.. "The metabolomic profile of visceral adipose tissue varies with BMI and glycemic status (¿O perfil metabólico do tecido adiposo visceral varia de acordo com o IMC e status glicémico¿)". Paper presented in 16th Portuguese Congress of Diabetes, 2020.
  2. Morais, Tiago; Seabra, Alexandre; Patrício, Bárbara G; Guimarães, Marta; Nora, Mário; Oliveira, Pedro F; Alves, Marco G; Monteiro, Mariana P.. "Visceral adipose tissue of obese pre-diabetic individuals have a distict exometabolomic profile". Paper presented in II Meeting of the Doctoral Degree in Biomedical Sciences, 2019.
  3. Alexandre, Seabra; Morais, Tiago; Patrício, Bárbara G; Nora, Mário; Oliveira, Pedro F; Alves, Marco G; Monteiro, Mariana P.. "Visceral adipose tissue of patients with obesity and pre-diabetes has a distinct exometabolomic profiling signature". Paper presented in EASO New Investigators United Autumn School, 2019.
  4. Palha, António M.; Pereira, Sofia S.; Santos, Madalena; Morais, Tiago; Maia, A.F.; Guimarães, Marta; Nora, Mário; Monteiro, Mariana P.. "Diferente distribuição de células secretoras de incretinas poderão potenciar diferentes resultados no perfil endócrino". 2016.
  5. Morais, Tiago; Patrício, Bárbara; Pereira, Sofia S.; Santos, Madalena; Moreia, Ângela; Andrade, Sara; Monteiro, Duarte; et al. "Effect of chronic glp-1 exposure on the morphology of pancreatic islets of intact and truncal vagotomized rats.". 2015.
  6. Pereira, Sofia S; Máximo, Valdemar; Coelho, Ricardo; Vinagre, João; Morais, Tiago; Costa, Manuel; Soares, Paula; et al. "TERT promoter mutations and TERT expression in adrenocortical tissues". Paper presented in XX Curso Pós-Graduado de Endocrinologia, Diabetes e Metabolismo, Porto, Portugal, 2014.
  7. Pereira, Sofia S.; Morais, Tiago; Santos, Madalena; Monteiro, Mariana P.; Pignatelli, Duarte. "Immunohistochemistry markers in the differential diagnosis of adrenocortical tumors.". 2013.
Journal article
  1. Tiago Morais; Pereira SS; Sara Andrade; Diogo Neves; Marta Guimarães; Mário Nora; Marcos C. Carreira; Felipe F. Casanueva; Monteiro MP. "GLP-1 Increases Circulating Leptin Levels in Truncal Vagotomized Rats". Biomedicines 11 5 (2023): 1322-1322. http://dx.doi.org/10.3390/biomedicines11051322.
    10.3390/biomedicines11051322
  2. Morais, Tiago; Seabra, Alexandre L.; Patrício, Bárbara G.; Carrageta, David F.; Guimarães, Marta; Nora, Mário; Oliveira, Pedro F.; Alves, Marco G.; Monteiro, Mariana P.. "Dysglycemia Shapes Visceral Adipose Tissue’s Response to GIP, GLP-1 and Glucagon in Individuals with Obesity". Metabolites 13 5 (2023): 587. http://dx.doi.org/10.3390/metabo13050587.
    10.3390/metabo13050587
  3. Esteves, Mário; Silva, Carina; Bovolini, António; Pereira, Sofia S.; Morais, Tiago; Moreira, Ângela; Costa, Madalena M.; Monteiro, Mariana P; Duarte, Jose Alberto. "Regular Voluntary Running is Associated with Increased Tumor Vascularization and Immune Cell Infiltration and Decreased Tumor Growth in Mice". International Journal of Sports Medicine 44 06 (2023): 427-437. http://dx.doi.org/10.1055/a-2008-7732.
    10.1055/a-2008-7732
  4. Correia, Ana S.; Pereira, Sara C.; Morais, Tiago; Martins, Ana D.; Monteiro, Mariana P.; Alves, Marco G.; Oliveira, Pedro F.. "Obesity-Related Genes Expression in Testes and Sperm Parameters Respond to GLP-1 and Caloric Restriction". Biomedicines 10 10 (2022): 2609. http://dx.doi.org/10.3390/biomedicines10102609.
    10.3390/biomedicines10102609
  5. Andrade, Sara; Morais, Tiago; Sandovici, Ionel; Seabra, Alexandre L.; Constância, Miguel; Monteiro, Mariana P.. "Adipose Tissue Epigenetic Profile in Obesity-Related Dysglycemia - A Systematic Review". Frontiers in Endocrinology 12 (2021): http://dx.doi.org/10.3389/fendo.2021.681649.
    10.3389/fendo.2021.681649
  6. Morais, Tiago. "Visceral Adipose Tissue Displays Unique Metabolomic Fingerprints in Obesity, Pre-Diabetes and Type 2 Diabetes". International Journal of Molecular Sciences 22 11 (2021): 5695-5695. http://dx.doi.org/10.3390/ijms22115695.
    10.3390/ijms22115695
  7. Esteves M; Silva C; Pereira SS; Morais T; Moreira Â; Costa MM; Monteiro MP; Duarte JA. "Regular Voluntary Running Inhibits Androgen-Independent Prostate Cancer Growth in Mice.". Journal of physical activity & health (2021): http://europepmc.org/abstract/med/33848979.
    10.1123/jpah.2020-0761
  8. Lobato CB; Pereira SS; Guimarães M; Morais T; Oliveira P; de Carvalho JPM; Nora M; Monteiro MP. "Use of flash glucose monitoring for post-bariatric hypoglycaemia diagnosis and management.". Scientific reports (2020): http://europepmc.org/abstract/med/32632211.
    10.1038/s41598-020-68029-8
  9. Martins, A.D.; Jarak, I.; Morais, T.; Carvalho, R.A.; Oliveira, P.F.; Monteiro, M.P.; Alves, M.G.. "Caloric restriction alters the hormonal profile and testicular metabolome, resulting in alterations of sperm head morphology". American journal of physiology. Endocrinology and metabolism 318 1 (2020): E33-E43. http://www.scopus.com/inward/record.url?eid=2-s2.0-85077762000&partnerID=MN8TOARS.
    10.1152/ajpendo.00355.2019
  10. Guimarães, Marta; Morais, Tiago; Pereira, Sofia S.; Monteiro, Ana; Vilaça, Ana; Ferreira, Tiago; Castro, Tiago; et al. "HEPATIC CELL PROLIFERATION PEAKS ONE WEEK AFTER PORTAL VEIN LIGATION AND IS NOT ENHANCED BY INSULIN (EXPERIMENTAL STUDY)". (2020): https://revista.spcir.com/index.php/spcir/article/view/576.
    10.34635/rpc.576
  11. Morais, Tiago. "GLP-1 induces alpha cell proliferation and overrides leptin suppression induced by negative energy balance in vagotomized rats.". Journal of cellular biochemistry (2019): https://doi.org/10.1002/jcb.28719.
    10.1002/jcb.28719
  12. Morais, Tiago. "Acute effect of an amino acid mixture in the rat glycemic profile". (2019): http://dx.doi.org/10.1002/jcb.28576.
    10.1002/jcb.28576
  13. Pereira, S.S.; Pereira, R.; Santos, A.P.; Costa, M.M.; Morais, T.; Sampaio, P.; Machado, B.; et al. "Higher IL-6 peri-tumoural expression is associated with gastro-intestinal neuroendocrine tumour progression". Pathology 51 6 (2019): 593-599. http://www.scopus.com/inward/record.url?eid=2-s2.0-85071073687&partnerID=MN8TOARS.
    10.1016/j.pathol.2019.07.001
  14. Costa, M.; Trovão Lima, A.; Morais, T.; Almeida, R.F.; Nora, M.; Guimarães, M.; Monteiro, M.P.. "Does Reconstruction Type After Gastric Resection Matters for Type 2 Diabetes Improvement?". Journal of Gastrointestinal Surgery (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85066799086&partnerID=MN8TOARS.
    10.1007/s11605-019-04255-4
  15. Palha, A.M.; Pereira, S.S.; Costa, M.M.; Morais, T.; Maia, A.F.; Guimarães, M.; Nora, M.; Monteiro, M.P.. "Differential GIP/GLP-1 intestinal cell distribution in diabetics’ yields distinctive rearrangements depending on Roux-en-Y biliopancreatic limb length". Journal of Cellular Biochemistry 119 9 (2018): 7506-7514. http://www.scopus.com/inward/record.url?eid=2-s2.0-85053537465&partnerID=MN8TOARS.
    10.1002/jcb.27062
  16. Patrício, B.G.; Morais, T.; Guimarães, M.; Veedfald, S.; Hartmann, B.; Hilsted, L.; Holst, J.J.; Nora, M.; Monteiro, M.P.. "Gut hormone release after gastric bypass depends on the length of the biliopancreatic limb". International Journal of Obesity (2018): 1-10. http://www.scopus.com/inward/record.url?eid=2-s2.0-85047355948&partnerID=MN8TOARS.
    10.1038/s41366-018-0117-y
  17. Pereira, P.R.; Guimarães, M.; Morais, T.; Pereira, S.S.; Nora, M.; Monteiro, M.P.. "Diabetic and Elder Patients Experience Superior Cardiovascular Benefits After Gastric Bypass Induced Weight Loss". Frontiers in Endocrinology 9 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85062618065&partnerID=MN8TOARS.
    10.3389/fendo.2018.00718
  18. Nora, M.; Morais, T.; Almeida, R.; Guimarães, M.; Monteiro, M.P.. "Should Roux-en-Y gastric bypass biliopancreatic limb length be tailored to achieve improved diabetes outcomes?". Medicine (United States) 96 48 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85036572876&partnerID=MN8TOARS.
    10.1097/MD.0000000000008859
  19. Pereira, Filipe; Pereira, Sofia S.; Mesquita, Marta; Morais, Tiago; Costa, Madalena M.; Quelhas, Pedro; Lopes, Carlos; Monteiro, Mariana P.; Leite, Valeriano. "Lymph Node Metastases in Papillary and Medullary Thyroid Carcinoma Are Independent of Intratumoral Lymphatic Vessel Density". European Thyroid Journal 6 2 (2017): 57-64. http://dx.doi.org/10.1159/000457794.
    10.1159/000457794
  20. Crujeiras AB; Cabia B; Carreira MC; Amil M; Cueva J; Andrade S; Seoane LM; et al. "Secreted factors derived from obese visceral adipose tissue regulate the expression of breast malignant transformation genes.". (2016): http://europepmc.org/abstract/med/26443342.
    10.1038/ijo.2015.208
  21. Tiago P. Guedes; Sofia Martins; Madalena Costa; Sofia S. Pereira; Tiago Morais; Agostinho Santos; Mário Nora; Mariana P. Monteiro. "Detailed characterization of incretin cell distribution along the human small intestine". Surgery for Obesity and Related Diseases 11 6 (2015): 1323-1331. http://dx.doi.org/10.1016/j.soard.2015.02.011.
    10.1016/j.soard.2015.02.011
  22. Moreira, Â.; Pereira, S.S.; Costa, M.; Morais, T.; Pinto, A.; Fernandes, R.; Monteiro, M.P.. "Adipocyte secreted factors enhance aggressiveness of prostate carcinoma cells". PLoS ONE 10 4 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84928807118&partnerID=MN8TOARS.
    10.1371/journal.pone.0123217
  23. Morais, Tiago. "Vaccines for metabolic diseases: current perspectives". Vaccine: Development and Therapy (2014): http://www.dovepress.com/vaccines-for-metabolic-diseases-current-perspectives-peer-reviewed-article-VDT.
    10.2147/VDT.S47623
  24. Fraga S; Brandão A; Soares ME; Morais T; Duarte JA; Pereira L; Soares L; et al. "Short- and long-term distribution and toxicity of gold nanoparticles in the rat after a single-dose intravenous administration.". (2014): http://europepmc.org/abstract/med/24941462.
    10.1016/j.nano.2014.06.005
  25. Nora, M.; Guimarães, M.; Almeida, R.; Martins, P.; Gonçalves, G.; Santos, M.; Morais, T.; Freitas, C.; Monteiro, M.P.. "Excess body mass index loss predicts metabolic syndrome remission after gastric bypass". Diabetology and Metabolic Syndrome 6 1 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84891769865&partnerID=MN8TOARS.
    10.1186/1758-5996-6-1
  26. Moreira Â; Pereira SS; Machado CL; Morais T; Costa M; Monteiro MP; Moreira, Â.; et al. "Obesity inhibits lymphangiogenesis in prostate tumors.". International Journal of Clinical and Experimental Pathology 7 1 (2014): 348-352. http://europepmc.org/abstract/med/24427356.
  27. Morais, Tiago. "The emerging role of the molecular marker p27 in the differential diagnosis of adrenocortical tumors". (2013):
    10.1530/ec-13-0025
  28. Morais, T.; Soares, M.E.; Duarte, J.A.; Soares, L.; Maia, S.; Gomes, P.; Pereira, E.; et al. "Effect of surface coating on the biodistribution profile of gold nanoparticles in the rat". European Journal of Pharmaceutics and Biopharmaceutics 80 1 (2012): 185-193. http://www.scopus.com/inward/record.url?eid=2-s2.0-83955161689&partnerID=MN8TOARS.
    10.1016/j.ejpb.2011.09.005
  29. Morais, Tiago. "Tetanic failure due to decreased endogenous adenosine A2A tonus operating neuronal Cav1 (L-type) influx in Myasthenia gravis". (2011):
    10.1111/j.1471-4159.2011.07216.x
  30. Morais, T.; Soares, M. Elisa; Fraga, S.; Carmo, H.; Duarte, J. Alberto; Bastos, M. Lourdes. "Biokinetics of gold nanoparticles in the rat". Toxicology Letters 196 (2010): S275-S276. http://dx.doi.org/10.1016/j.toxlet.2010.03.1134.
    10.1016/j.toxlet.2010.03.1134
Distinctions

Award

2017 Prémio Nacional de Diabetologia 2017
Sociedade Portuguesa de Diabetologia, Portugal
2016 Prémio Melhor Comunicação Oral na 50ª Reunião da Sociedade Anatómica Portuguesa / 3ª Reunião Científica da Associação Anatómica Portuguesa
2015 1º Prémio para melhor artigo original publicado na revista portuguesa de endocrinologia, diabetes e metabolismo (RPEDM) em 2015 (investigação clínica)
2013 Prémio Prof. Manuel Pinheiro Hargreaves