Beatriz Serra (E01D-8C52-B396)

Curriculum Vitae

Beatriz Serra

Identification

Personal identification

Full name: Beatriz Serra

Citation names

Serra, Beatriz

Author identifiers

Ciência ID: E01D-8C52-B396

Email addresses

bserra@cnc.uc.pt (Professional)
serra.m.beatriz@gmail.com (Personal)

Knowledge fields

Medical and Health Sciences - Medical Biotechnology - Gene-based Diagnostics and Therapeutic Interventions

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese (Mother tongue)
English	Intermediate (B1)	Upper intermediate (B2)	Upper intermediate (B2)	Upper intermediate (B2)

Education

	Degree	Classification
2022/10/10 - 2026 Ongoing	Experimental Biology and Biomedicine (Doutoramento) Instituto de Investigação Interdisciplinar, Universidade de Coimbra, Portugal
2020/08/01 - 2020/10/31 Concluded	Specialization course- Scientific Research Methodologies - I&D: Therapy gene and stem cells (Outros) Instituto de Investigação Interdisciplinar, Universidade de Coimbra, Portugal	Aprovado com Muito Bom
2017/09 - 2019/12 Concluded	Ciências Biofarmacêuticas (Mestrado) Faculdade de Farmácia, Universidade de Lisboa, Portugal "Quality and reporting of clinical practice guidelines on the management of Parkinson's Disease" (THESIS/DISSERTATION)	17
2014/08 - 2017/06 Concluded	Bioquímica (Licenciatura) Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Portugal "Efeitos oxidativos de misturas de Hidrocarbonetos Aromáticos Policíclicos em células hepáticas" (THESIS/DISSERTATION)	14

Affiliation

Science

	Category Host institution	Employer
2021/10/01 - 2022/06/30	Researcher (Research)	Universidade de Coimbra, Portugal
	Center for Neuroscience and Cell Biology (CNC), Universidade de Coimbra, Portugal
2020/12/01 - 2021/07/31	Researcher (Research)	National Ataxia Foundation, United States
	Center for Neuroscience and Cell Biology (CNC), Universidade de Coimbra, Portugal
2020/08/01 - 2020/10/31	Research Trainee (Research)	Fundação para a Ciência e a Tecnologia, Portugal
	Center for Neuroscience and Cell Biology (CNC), Universidade de Coimbra, Portugal
2018/10 - 2019/10	Research Trainee (Research)	Laboratório de Farmacologia Clínica e Terapêutica, Universidade de Lisboa, Portugal
	Faculdade de Medicina, Universidade de Lisboa, Portugal
2017/01 - 2017/06	Research Trainee (Research)	Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Portugal
	Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Portugal

Others

	Category Host institution	Employer
2020/05/18 - 2020/07/31	Laboratory Technician	Covid-19 Lab - CNC / ViraVector, Portugal
	Universidade de Coimbra ViraVector, Portugal (...)
2016/08/01 - 2016/08/19	Laboratory Technician (Trainee)	MICRODIAG, Laboratório de Anatomia Patológica, Portugal

Projects

Grant

	Designation	Funders
2022/08/01 - 2022/10/31	Intravenous delivery of the brain-targeting AAV-PHPeB encoding the cholesterol hydroxylase CYP46A1 into a mouse model of spinocerebellar ataxia type 3: a promise non-invasive therapeutic strategy 686213 Research Fellow Center for Neuroscience and Cell Biology (CNC), Universidade de Coimbra, Portugal	National Ataxia Foundation
2022/01/01 - 2022/06/30	Proof of concept evaluation of the ATXN3 LNA in the homozygous YAC hATXN3 Q84.2 mouse model PSE-2020-113 Research Fellow Center for Neuroscience and Cell Biology (CNC), Universidade de Coimbra, Portugal
2021/10/01 - 2021/12/31	HEALTHYAGING 2020 CENTRO-01-0145-FEDER-000012 Research Fellow Center for Neuroscience and Cell Biology (CNC), Universidade de Coimbra, Portugal	Concluded
2020/12/01 - 2021/12/31	Intravenous delivery of the brain-targeting AAV-PHPeB encoding the cholesterol hydroxylase CYP46A1 into a mouse model of spinocerebellar ataxia type 3: a promise non-invasive therapeutic strategy 686213 Research Fellow Center for Neuroscience and Cell Biology (CNC), Universidade de Coimbra, Portugal	National Ataxia Foundation
2020/08/01 - 2020/10/31	Verão com Ciência: "Sobrexpressão mediada da CYP46A1 como estratégia terapêutica para doenças neurológicas" 685385 Scientific Initiation Fellow Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal Center for Neuroscience and Cell Biology (CNC), Universidade de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Other

	Designation	Funders
2020/08 - 2021/12	Gene Therapy for Cerebellar Ataxias: restoring cholesterol metabolism by targeting brain cholesterol 24 hydroxylase (CYP46A1) - SCA-CYP; (E-RARE International Consortium) E-Rare-3 JTC 2017 Research Fellow

Outputs

Publications

Conference poster

Serra, Beatriz; Sónia P. Duarte; Françoise, PIGUET; Nathalie Cartier; Alves, Sandro; Pereira de Almeida, Luis ; Perfeito, Rita. Corresponding author: Perfeito, Rita. "Validation of the brain-targeting AAV- PHP.eB encoding cholesterol hydroxylase CYP46A1: a promising non-invasive therapeutic strategy for Spinocerebellar Ataxia Type 3". Paper presented in FENS Regional Meeting (FRM 2023), 2023.
Serra, Beatriz; Sónia P. Duarte; Nathalie Cartier; Alves, Sandro; Pereira de Almeida, Luis ; Perfeito, Rita. Corresponding author: Perfeito, Rita. "Intravenous delivery of the brain-targeting AAV-PHPeB encoding the cholesterol hydroxylase CYP46A1 into a mouse model of spinocerebellar ataxia type 3: a promising non-invasive therapeutic strategy". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience, Coimbra, Portugal, 2021.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2022/04/02	Non-invasive delivery of the brain-targeting AAV-PHP.eB encoding the cholesterol hydroxylase CYP46A1 into a mouse model of spinocerebellar ataxia type 3: a promising therapeutic strategy	Sociedade Portuguesa de Doenças do Movimento (Luso, Portugal)
2022/02/09	Validation of the brain-targeting AAV- PHPeB enconding cholesterol hydroxylase CYP46A1 as a therapeutic candidate for Spinocerebellar Ataxia Type-3	LII Reunião da Sociedade Portuguesa de Farmacologia, XL Reunião de Farmacologia Clínica e XXI Reunião de Toxicologia (Porto, Portugal)