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Identification

Personal identification

Full name
SARA CRISTINA LOURENÇO DOS REIS

Citation names

  • Reis, Sara
  • Sara L. Reis

Author identifiers

Ciência ID
DF19-8625-A0DD

Email addresses

  • screis@med.up.pt (Professional)

Addresses

  • Faculdade de Medicina da Universidade do Porto (FMUP), Centro de Investigação Médica (CIM), Biologia Experimental - pisos 4/5, 4200-450, Porto, Porto, Portugal (Professional)

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Medical and Health Sciences - Basic Medicine - Neurosciences

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2019/10/01 - 2024/09/01
Concluded
Life Sciences (Doktor (PhD))
Major in Neuroscience
Julius-Maximilians-Universität Würzburg Graduate School of Life Sciences, Germany
"An interoceptive role for glycinergic periaqueductal grey neurons during defensive states" (THESIS/DISSERTATION)
Magna Cum Laude
2015/09 - 2017/07
Concluded
Biologia Celular e Molecular (Mestrado integrado)
Universidade de Coimbra, Portugal
"Control of fear memory by adenosine receptors: role in the physiology of the related brain circuitry and implications for fear extinction and post-traumatic stress disorder" (THESIS/DISSERTATION)
18
2012/09 - 2015/07
Concluded
Biologia Humana (Licenciatura)
Universidade de Évora, Portugal
"“Genetic variablity in obese humans: polimorphisms and telomeres quantification", no grupo de Genética e metabolismo (nota final 19 (de 20))" (THESIS/DISSERTATION)
15.4
Affiliation

Science

Category
Host institution
Employer
2019/04/01 - 2024/09/30 Researcher (Research) Universitätsklinikum Würzburg Institut für Klinische Neurobiologie, Germany
Universitätsklinikum Würzburg Institut für Klinische Neurobiologie, Germany
2017/09/15 - 2019/04/01 Contracted Researcher (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2019/01/07 - 2019/01/28 Visiting Researcher (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Institut du cerveau et de la moelle épinière, France
Projects

Grant

Designation Funders
2024/11/01 - Current Neuronal circuits underlying social behavior: using a mouse model of autism to uncover the role of the auditory system in social interactions
2022.05228.PTDC - ASD-ASD
Post-doc Fellow
Universidade do Porto Faculdade de Medicina, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2019/10/01 - 2024/09/01 An interoceptive role for glycinergic periaqueductal grey neurons during defensive states
DFG project grant (TO1124-1/2)
PhD Student Fellow
Universitätsklinikum Würzburg Institut für Klinische Neurobiologie, Germany
Fundação para a Ciência e a Tecnologia
2017/09/04 - 2019/03/31 Adenosine a1 and a2a receptors differently control synaptic plasticity in the dorsal and ventral hippocampus
CENTRO-01-0145-FEDER-000008
Research Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Concluded
2017/09/01 - 2019/03/31 Adenosine A2AR modulate the extinction of fear memories
CENTRO-01-0145-FEDER-000008
Research Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Ongoing
Outputs

Publications

Conference poster
  1. Sara L. Reis; Jérémy Signoret-Genest; Philip Tovote. "Cardiac interoceptive role for glycinergic periaqueductal grey circuits during defensive states". Paper presented in FENS Forum 2024, Viena (https://fens2024.abstractserver.com/program/#/details/presentations/4661), 2024.
  2. Sara L. Reis; Jérémy Signoret-Genest; Philip Tovoe. "An interoceptive role for glycinergic periaqueductal grey neurons during defensive states". Paper presented in 15th Göttingen Meeting of the German Neuroscience Society, 2023.
  3. Sara L. Reis; Jérémy Signoret-Genest; Philip Tovote. "An interoceptive role for glycinergic periaqueductal grey neurons during defensive states". Paper presented in SfN 2022, San Diego (https://www.sfn.org/-/media/SfN/Documents/NEW-SfN/Meetings/Neuroscience-2022/Abstracts/Abstract-PDFs/SFN22_Abstracts-PDF-Posters_SUN_PM.pdf -- Page 756), 2022.
  4. Sara L. Reis; Jérémy Signoret-Genest; Philip Tovote. "An interoceptive role of Glycinergic neurons during defensive states". Paper presented in FENS Forum 2022, Paris (https://www.world-wide.org/fens-22/interoceptive-role-glycinergic-periaqueductal-d070820b/), 2022.
  5. Reis, Sara; Jérémy Signoret-Genest; Philip Tovote. "An interoceptive role of Glycinergic neurons during defensive states". Paper presented in Eureka 2021 – International symposium, 2021.
  6. Sara L. Reis; Henrique B.Silva; Almeida, Margarida; Cunha, Rodrigo A.; Canas, Paula M.; Ana Patrícia Simões. "Adenosinergic system: a different impact in the dorsal versus ventral hippocampus". Paper presented in FENS Forum 2018, Berlin, 2018.
  7. Sara L. Reis; Henrique B.Silva; Cunha, Rodrigo A.; Ana Patrícia Simões. "Different impact of the adenosinergic system in the dorsal versus ventral hippocampus". Paper presented in XV meeting of the Portuguese Society for Neuroscience, Braga (https://meetingspn.weebly.com/presentations.html), 2017.
Journal article
  1. Reis, Sara L.; Monteiro, Patricia. "From synaptic dysfunction to atypical emotional processing in autism". FEBS Letters 598 3 (2024): 269-282. http://dx.doi.org/10.1002/1873-3468.14801.
    10.1002/1873-3468.14801
  2. Signoret-Genest, Jérémy; Schukraft, Nina; L. Reis, Sara; Segebarth, Dennis; Deisseroth, Karl; Tovote, Philip. "Integrated cardio-behavioral responses to threat define defensive states". Nature Neuroscience 26 (2023): 447-457. http://dx.doi.org/10.1038/s41593-022-01252-w.
    Accepted • 10.1038/s41593-022-01252-w
  3. Khayenko, Vladimir; Schulte, Clemens; Reis, Sara L.; Avraham, Orly; Schietroma, Cataldo; Worschech, Rafael; Nordblom, Noah F.; et al. "A Versatile Synthetic Affinity Probe Reveals Inhibitory Synapse Ultrastructure and Brain Connectivity**". Angewandte Chemie International Edition 61 30 (2022): http://dx.doi.org/10.1002/anie.202202078.
    Accepted • 10.1002/anie.202202078
  4. Reis, Sara L.; Silva, Henrique B.; Almeida, Margarida; Cunha, Rodrigo A.; Simões, Ana P.; Canas, Paula M.. "Adenosine A1 and A2A receptors differently control synaptic plasticity in the mouse dorsal and ventral hippocampus". Journal of Neurochemistry 151 2 (2019): 227-237. http://dx.doi.org/10.1111/jnc.14816.
    Accepted • 10.1111/jnc.14816
Thesis / Dissertation
  1. "An interoceptive role for glycinergic periaqueductal grey neurons during defensive states". PhD, Julius-Maximilians-Universität Würzburg, 2024. https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/year/2024/docId/32751.
  2. "CONTROL OF FEAR MEMORY BY ADENOSINE RECEPTORS: role in the physiology of the related brain circuitry and implications for fear extinction and post-traumatic stress disorder". Master, Universidade de Coimbra Centro de Neurociências e Biologia Celular, 2017. https://estudogeral.uc.pt/handle/10316/82884.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2019/02/07 Adenosine A2A receptores modulate the extinction of fear memories XLVIX meeting of the Portuguese Society of Pharmacology
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2017/02/04 ATP-derived adenosine activates A2A receptors controlling long-term potentiation in the amygdala XLVII meeting of the Portuguese Society of Pharmacology, Coimbra.
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2019/08 - 2019/11 Glycinergic expression in the brainstem and spinal cord
Co-supervisor
Biology (Scientific initiation)
Julius-Maximilians-Universität Würzburg, Germany

Event organisation

Event name
Type of event (Role)
Institution / Organization
2013/09/15 - 2014/05/04 3 Day Startup é uma atividade de 72 horas intensivas com hands-on workshops. Este programa visa ensinar as skills necessárias na área de empreendorismo a estudantes universitários através de mentores especialistas da área. No final da atividade cada grupo de participantes apresenta a sua ideia de negocio a um júri que poderá vir a financia-la. (2014/05/02 - 2014/05/04)
Workshop
Universidade de Évora, Portugal

3Day Startup, United States

Event participation

Activity description
Type of event
Event name
Institution / Organization
2024/11/16 - 2024/11/17 The 1st Phelan-McDermid Portugal Conference is an event bringing together leading experts in Phelan-McDermid Syndrome (PMS) to share knowledge and insights. The conference also included roundtable discussions and sessions dedicated to therapeutic approaches, providing a comprehensive platform for learning and collaboration among professionals, families, and individuals affected by PMS
Conference
1ª Conferência Phelan-McDermid Portugal
2021/10/30 - 2021/10/31 Autumm School – Translational Neuroscience (with poster presentation)
Symposium
2017/10/02 - 2017/10/21 The Cajal course on Connectomics is an intensive three-week course that guides participants through the theory and practice of state-of-the art methods to address pertinent questions in the field of structural/functional connectomics — from mice to humans. This goal will be achieved through a unique balance of lectures from worldwide experts in their respective fields and experimental demonstrations and hands-on laboratory work (mini-projects) in small groups.
Other
Connectomics: from Micro- to Meso- and Macro-Scales course 2017” of the CAJAL Advanced Neuroscience Training Programm
Fédération Bordeaux Neurocampus, France

Ad Hoc journal article review

Journal title (ISSN) Publisher
2024 - Current Advanced Science
2022 - Current Journal of Neuroscience
2020 - Current Nature Neuroscience

Mentoring / Tutoring

Topic Student name
2018/09 - 2019/04 Adenosine A2A receptors in the amygdala: slice recordings Vanessa Lourenço
2018/06 - 2018/07 Adenosine A2A receptors in the amygdala: implication for fear memory and mood disorders Ana Sá
Distinctions

Award

2018 SPN travel award to attend the 11th FENS forum in Berlin, July 7-11th 2018
Sociedade Portuguesa de Neurociências, Portugal
2017 CAJAL stipend award to attend the “Connectomics: from Micro-to-Meso- and Macro-Scales course 2017” of the CAJAL Advanced Neuroscience Training Programme held at the Bordeaux Neurocampus in Bordeaux, France, on October 2-21st 2017
Federation of European Neuroscience Societies, Belgium

Other distinction

2017 SPN (Portuguese Society of neuroscience) Scholarship for poster presentation in the XV meeting of the Portuguese Society of Neuroscience
Sociedade Portuguesa de Neurociências, Portugal