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Pedro Cravo (PC) earned a Bachelor's degree in Biotechnological Engineering, a Master's degree in Molecular and Biochemical Parasitology, and a Ph.D. in Genetics from the University of Edinburgh (UK), completed in 2001. PC has dedicated his career mainly to studying the molecular mechanisms of resistance to antimalarial drugs, using classical genetic tools combined with new genomic and bioinformatics concepts and technologies and to the discovery of new drugs through computational strategies. Currently, he is an Assistant Professor at the Institute of Hygiene and Tropical Medicine, at Universidade Nova de Lisboa (IHMT-NOVA), Portugal, where he continues researching into the mechanisms of resistance to antimalarial drugs and other infectious diseases of mostly tropical origin. At IHMT, he is a member of the Scientific Board of the Research Center "Global Health and Tropical Medicine" (GHTM), where he coordinates the cross-cutting issue "Antimicrobial Resistance and Drug Discovery". Within the scope of IHMT, he also coordinates the PT-OPENSCREEN infrastructure and the NOVA Green Labs initiative. PC has authored 70 publications in peer-reviewed journals, with more than 3000 citations and an holds an h-index of 33.
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Identification

Personal identification

Full name
Pedro Vitor Lemos Cravo

Citation names

  • Cravo, Pedro
  • Cravo, Pedro Vitor Lemos

Author identifiers

Ciência ID
DF15-8F85-8B9C
ORCID iD
0000-0003-1675-4504
Google Scholar ID
http://scholar.google.com.br/citations?user=6VR4d9EAAAAJ&hl=pt-BR
Researcher Id
G-3532-2012

Email addresses

  • pedrovcravo@gmail.com (Professional)

Telephones

Telephone
  • 213652600 Ext.: 303 (Professional)

Addresses

  • GHTM/Instituto de Higiene e Medicina Tropical, Rua da Junqueira, n. 100, 1349-008, Lisbon, Lisbon, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Health Sciences - Tropical Medicine

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Spanish; Castilian Upper intermediate (B2) Upper intermediate (B2) Elementary (A2) Upper intermediate (B2) Beginner (A1)
Education
Degree Classification
1996/10/01 - 2001/07/31
Concluded
 Genetics (Doctor of Philosophy)
The University of Edinburgh, United Kingdom
"The genetics of resiostance to quinoline-containing antimalarias in Plasmodium chabaudi" (THESIS/DISSERTATION)
1993/10/01 - 1994/11/01
Concluded
 Molecular and Biochemical Parasitology (Master)
University of Salford, United Kingdom
1989/10/01 - 1992/12/01
Concluded
 Biotecnologia (Bacharelato)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
Affiliation

Science

Category
Host institution 		Employer
2001/12/01 - 2003/02/01 Postdoc (Research) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2001/02/01 - 2001/11/01 Postdoc (Research) The University of Edinburgh, United Kingdom
The University of Edinburgh, United Kingdom

Teaching in Higher Education

Category
Host institution 		Employer
2017/03/01 - Current Assistant Professor (University Teacher) Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2011/01/03 - 2016/10/01 Assistant Professor (University Teacher) Universidade Federal de Goiás Instituto de Patologia Tropical e Saúde Pública, Brazil
Universidade Federal de Goiás Instituto de Patologia Tropical e Saúde Pública, Brazil
2003/03/01 - 2010/12/31 Assistant Professor (University Teacher) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Projects

Grant

Designation Funders
2018/06/06 - Current Desenvolvimento de Novas Ferramentas para Busca e Validação de Alvos Moleculares para Terapia e Profilaxia contra Plasmodium vivax
NA
Researcher
Universidade Estadual de Campinas Departamento de Genética Evolução e Bioagentes, Brazil
 Fundação de Amparo à Pesquisa do Estado de São Paulo
Ongoing
2018/10/01 - 2021/09/30 Identification of new antimalarial treatments through a target-centred “drug repositioning” approach
PTDC/SAU-PAR/28459/2017
Principal investigator
Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2015/01/03 - 2018/01/02 Identificação de novos fármacos antimaláricos através de estratégia de quimiogenômica por reposicionamento e validação experimental
NA
Principal investigator
Universidade Federal de Goiás Instituto de Patologia Tropical e Saúde Pública, Brazil
 Conselho Nacional de Desenvolvimento Científico e Tecnológico
Concluded
2007/10/01 - 2010/09/29 EARLY DETECTION OF THE BIOLOGICAL AND GENETIC DETERMINANTS OF RESISTANCE TO ARTEMISININ-BASED COMBINATION THERAPY IN MALARIA PARASITES
info:eu-repo/grantAgreement/FCT/SFRH/SFRH2%FBD2%F315182%F2006/PT
Principal investigator
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2005/10/01 - 2008/10/01 Applications of transfection technology for drug screening and immunological studies in tropical parasitic diseases
NA
Invited Scientist Fellow
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
 Organisation mondiale de la Santé
Concluded
2005/10/01 - 2008/05/05 Identification of genes influencing artemisinin and chloroquine resistance in malaria parasites by Linkage Group Selection
NA
Researcher
The University of Edinburgh, United Kingdom
 Medical Research Council
Ongoing
2003/06/01 - 2006/05/31 Development of a malaria resistance DNA chip as a public health tool for the management of Plasmodium falciparum malaria drug resistance
NA
Principal investigator
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
 Community Research and Development Information Programme
Concluded
2002/10/01 - 2005/09/29 STUDIES ON THE GENETICS OF DRUG RESISTANCE IN MALARIA
info:eu-repo/grantAgreement/FCT/SFRH/SFRH2%FBPD2%F55682%F2001/PT
Principal investigator
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2001/10/01 - 2003/10/31 STUDIES ON THE GENETICS OF DRUG RESISTANCE IN MALARIA
SFRH/BPD/5568/2001
 Fundação para a Ciência e a Tecnologia
Concluded
1997/10/01 - 2001/07/31 GENETICS OF QUININE RESISTANCE IN MALARIA PARASITES
PRAXIS XXI/BD/13824/97
 Fundação para a Ciência e a Tecnologia
Concluded
1995/01/01 - 1995/12/31 STUDIES ON THE BIOLOGY OF MALARIA WITH SPECIAL RELEVANCE TO DIAGNOSIS, IMUNOLOGY, DRUGS RESISTANCE AND VECTORS
GGP XXI/BIC/888/94
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2021/01/01 - 2025/12/31 Translation and Innovation towards Global Health
LA/P/0117/2020
10.54499/LA/P/0117/2020
Universidade Nova de Lisboa, Portugal

Universidade NOVA de Lisboa Comprehensive Health Research Centre, Portugal

Universidade de Coimbra, Portugal

Universidade de Évora, Portugal

Universidade de Lisboa Centro de Matemática Aplicações Fundamentais e Investigação Operacional, Portugal

Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal

Universidade de Lisboa Faculdade de Medicina Dentária, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/05/01 - 2025/04/30 Mechanisms of action and resistance to the antimalarial Purydrazide
PTDC/SAU-PAR/2766/2021
10.54499/PTDC/SAU-PAR/2766/2021
Universidade do Minho, Portugal

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

BnML Behavioral and Molecular Lab Lda, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/03/21 - 2022/09/30 MALREP - Identification of new antimalarial treatments through a target-centred "drug repositioning" approach
PTDC_SAU_PAR_28459_2017
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018/10/01 - 2022/09/30 Identification of new antimalarial treatments through a target-centred "drug repositioning" approach
PTDC/SAU-PAR/28459/2017
Universidade Nova de Lisboa, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2019/01/01 - 2019/12/31 Global Health and Tropical Medicine
UID/Multi/04413/2019
Universidade Nova de Lisboa, Portugal

Universidade Nova de Lisboa Saúde Global e Medicina Tropical, Portugal

Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2012/12/31 Strategic Project - LA 18 - 2011-2012
PEst-OE/SAU/LA0018/2011
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2008/01/01 - 2011/09/30 Genetics of accelerated acquisition of drug resistance to multiple drugs (ARMD) in malaria parasites: dynamics and fitness studies.
PTDC/BIA-MIC/65861/2006
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/09/01 - 2011/03/31 Early identification of the biological and genetic determinants of resistance to Artemisinin-based Combination Therapy in malaria parasites
PTDC/SAU-MII/65028/2006
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2005/09/01 - 2007/12/31 Population structure and gene flow of malaria parasites on islands.
POCI/SAU-ESP/56903/2004
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2005/08/01 - 2007/12/31 Genetic studies on drug resistance and host susceptibility in Leishmania infantum infection
POCI/CVT/56357/2004
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2005/08/01 - 2007/09/30 Biochemical characterization and inhibition studies of recombinant cysteine proteases of Plasmodium chabaudi, an animal model for human malaria.
POCI/SAU-ESP/57696/2004
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal

Instituto de Biologia Experimental e Tecnológica, Portugal

Universidade de Lisboa Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Cassiano, G.C.; Tavella, T.A.; Nascimento, M.N.; Rodrigues, D.A.; Cravo, P.V.L.; Andrade, Carolina Horta; Costa, Fabio Trindade Maranhão. "Targeting malaria protein kinases". In Advances in Protein Chemistry and Structural Biology, 225-274. London, United Kingdom: Elsevier, 2021.
    Published • 10.1016/bs.apcsb.2020.10.004
  2. G.C. Cassiano; T.A. Tavella; M.N. Nascimento; D.A. Rodrigues; Pedro Cravo; C.H. Andrade; F.T.M. Costa. "Targeting malaria protein kinases". 225-274. Elsevier, 2021.
  3. M.M. Inácio; R.B. Machado; J. Rodrigues; F.G.G. Chapadense; W. Goes; E. Novaes; Pedro Cravo. "Construção de uma vacina contra Toxoplasmose por vacionologia reversa e estratégia imunômica". 55–56-55–56. Roland E. Junior - Gr{\'a, 2018.
Book review
  1. Rodrigues, Liliana; Cravo, Pedro; Viveiros, Miguel. "Efflux pump inhibitors as a promising adjunct therapy against drug resistant tuberculosis". http://hdl.handle.net/10362/110134.
    https://doi.org/10.1080/14787210.2020.1760845
Conference abstract
  1. Rodrigues, L; Cravo, Pedro Vitor Lemos; Viveiros, Miguel. "Targeting membrane transporters and energy metabolism in Mycobacterium tuberculosis through in silico drug repurposing". Paper presented in European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), 2020.
  2. Liliana Rodrigues; Pedro Cravo; Miguel Viveiros. "In silico repurposing of approved drugs against tuberculosis: targeting membrane transporters and energy metabolism". 2019.
  3. Liliana Rodrigues; Pedro Cravo; Miguel Viveiros. "Chemogenomics and in silico repurposing as an innovative approach for rapid drug discovery in tuberculosis". 2019.
  4. O Ribeiro; f nogueira; Pedro Cravo; José Pedro Blanco Panadés Gil; Virgilio Estólio do Rosário; Vera Ribeiro. "Role of Drug Metabolising Enzymes in Antimalarial Drug Resistance". 2002.
Conference poster
  1. Julyana Cerqueira Buery; A.M.R.C. Duarte; F.E.C. Alencar; C. Furieri; S.L. Mendes; A.C. Loss; C.R. Vicente; et al. "One piece more in the puzzle of Plasmodium simium and Plasmodium vivax identity: detection of P. vivax in a liver sample of a howler-monkey". 2020.
  2. Liliana Rodrigues; Pedro Cravo; Miguel Viveiros. "Targeting membrane transporters and energy metabolism in Mycobacterium tuberculosis using an in silico repurposing-chemogenomics strategy". 2019.
  3. Martins, Tiago M.; Caldeira, R.A.; Pombo, J.L.; Afonso, A.; Cravo, Pedro Vitor Lemos; do Rosário, V.E.; novo, carlos; Berry, C.; Ana Gonçalves Domingos. "Plasmodium proteases as targets for malaria therapy". Paper presented in 1st Annual Workshop COST Action 857, Apicomplexan Biology in the post-genomic era, 2004.
  4. Martins, Tiago M.; Wyatt, D.M.; Cravo, Pedro Vitor Lemos; do Rosário, V.E.; novo, carlos; Berry, C.; Ana Gonçalves Domingos. "Activity of the Plasmodium chabaudi recombinant haemoglobinase plasmepsin I". Paper presented in X Congresso Nacional de Biotecnologia, 2003.
  5. Pombo, J.L.; Martins, Tiago M.; Caldeira, R.A.; Cravo, Pedro Vitor Lemos; do Rosário, V.E.; novo, carlos; Ana Gonçalves Domingos. "Degradation of haemoglobin by recombinant aspartic proteinase from Plasmodium chabaudi, plasmepsin I". Paper presented in X Congresso Nacional de Biotecnologia, 2003.
  6. Martins, Tiago M.; Wyatt, D.M.; Cravo, Pedro Vitor Lemos; novo, carlos; Berry, C.; Ana Gonçalves Domingos. "Expression and activity of the Plasmodium chabaudi recombinant haemoglobinase Plasmepsin I". Paper presented in 11th European Congress on Biotechnology, Basel, 2003.
Journal article
  1. Cassiano, Gustavo Capatti; Martinelli, Axel; Mottin, Melina; Neves, Bruno Junior; Andrade, Carolina Horta; Ferreira, Pedro Eduardo; Cravo, Pedro. "Whole genome sequencing identifies novel mutations in malaria parasites resistant to artesunate (ATN) and to ATN + mefloquine combination". Frontiers in Cellular and Infection Microbiology 14 (2024): http://dx.doi.org/10.3389/fcimb.2024.1353057.
    10.3389/fcimb.2024.1353057
  2. Gonçalves, Adriana F.; Lima-Pinheiro, Ana; Teixeira, Miguel; Cassiano, Gustavo Capatti; Cravo, Pedro; Ferreira, Pedro E.. "Mutation in the 26S proteasome regulatory subunit rpn2 gene in Plasmodium falciparum confers resistance to artemisinin". Frontiers in Cellular and Infection Microbiology 14 (2024): http://dx.doi.org/10.3389/fcimb.2024.1342856.
    10.3389/fcimb.2024.1342856
  3. Essoh, Anyse P.; Cassiano, Gustavo Capatti; Mandim, Filipa; Barros, Lillian; Gomes, Isildo; Medeiros, Márcia Melo; Moura, Mónica; Cravo, Pedro V.L.; Romeiras, Maria M.. "Antimalarial and cytotoxic activity of native plants used in cabo verde traditional medicine". (2023): http://hdl.handle.net/10198/29048.
    10.3390/plants12040963
  4. Pedro Cravo. "On the contribution of the rodent model Plasmodium chabaudi for understanding the genetics of drug resistance in malaria". Parasitology International 91 (2022): https://novaresearch.unl.pt/en/publications/8e37eab0-1d13-49de-8274-8c5107aee37d.
    10.1016/j.parint.2022.102623
  5. Anyse P. Essoh; Ângela Liberal; Ângela Fernandes; Maria Inês Dias; Carla Pereira; Filipa Mandim; Margarida Moldão-Martins; et al. "Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants". Pharmaceuticals 15 9 (2022): https://novaresearch.unl.pt/en/publications/95f88123-72b1-471c-81f3-e93c3f4eca98.
    10.3390/ph15091162
  6. Cravo, Pedro. "On the contribution of the rodent model Plasmodium chabaudi for understanding the genetics of drug resistance in malaria". (2022): http://hdl.handle.net/10362/142753.
    https://doi.org/10.1016/j.parint.2022.102623
  7. Essoh, Anyse P.; Liberal, Ângela; Fernandes, Ângela; Dias, Maria Inês; Pereira, Carla; Mandim, Filipa; Moldão-Martins, Margarida; et al. "Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants". (2022): http://hdl.handle.net/10400.5/25760.
  8. Tatyana Almeida Tavella; Noeli Soares Melo Da Silva; Natalie Spillman; Ana Carolina Andrade Vitor Kayano; Gustavo Capatti Cassiano; Adrielle Ayumi Vasconcelos; Antônio Pedro Camargo; et al. "Violacein-Induced Chaperone System Collapse Underlies Multistage Antiplasmodial Activity". ACS Infectious Diseases 7 4 (2021): 759-776. https://novaresearch.unl.pt/en/publications/2cdb0226-411c-4dc7-9c02-8de7f2600780.
    10.1021/acsinfecdis.0c00454
  9. Buery, Julyana Cerqueira; de Alencar, Filomena Euridice Carvalho de; Duarte, Ana Maria Ribeiro de Castro; Loss, Ana Carolina; Vicente, Creuza Rachel; Ferreira, Lucas Mendes; Fux, Blima; et al. "Atlantic Forest Malaria: A Review of More than 20 Years of Epidemiological Investigation". Microorganisms 9 1 (2021): 132. http://dx.doi.org/10.3390/microorganisms9010132.
    10.3390/microorganisms9010132
  10. Tavella, Tatyana Almeida; Da Silva, Noeli Soares Melo; Spillman, Natalie; Kayano, Ana Carolina Andrade Vitor; Cassiano, Gustavo Capatti; Vasconcelos, Adrielle Ayumi; Camargo, Antônio Pedro; et al. "Violacein-Induced Chaperone System Collapse Underlies Multistage Antiplasmodial Activity". (2021): http://hdl.handle.net/10362/116523.
    https://doi.org/10.1021/acsinfecdis.0c00454
  11. Letícia Tiburcio Ferreira; Juliana Rodrigues; Gustavo Capatti Cassiano; Tatyana Almeida Tavella; Kaira Cristina Peralis Tomaz; Djane Clarys Baia-Da-Silva; Macejane Ferreira Souza; et al. "Computational chemogenomics drug repositioning strategy enables the discovery of epirubicin as a new repurposed hit for Plasmodium falciparum and P. vivax". Antimicrobial Agents and Chemotherapy Vol. 64 n.º 9 (2020): e02041-e02058. https://novaresearch.unl.pt/en/publications/bd0d6aa8-16ae-4e0e-96cb-e77348291f84.
    10.1128/AAC.02041-19
  12. Cravo, Pedro; Rodrigues, Liliana; Viveiros, Miguel. "Efflux pump inhibitors as a promising adjunct therapy against drug resistant tuberculosis: a new strategy to revisit mycobacterial targets and repurpose old drugs". Expert Review of Anti-infective Therapy (2020):
    In press
  13. Cravo, Pedro; Cassiano, Gustavo C.. "Epirubicin as a potent antimalarial drug candidate identified by chemogenomics repurposing strategy". Antimicrobial Agents and Chemotherapy (2020):
  14. Francesca Guaracyaba Garcia Chapadense; Machado, Ricardo Luiz Dantas; Ventura, Ana Maria Revorêdo Da Silva; André Luiz Lisboa Areas; Renato Beilner Machado; Viana, Giselle Maria Rachid; Mariano Gustavo Zalis; Ana Maria Castro; Pedro Cravo. "Plasmodium falciparum malarial parasites from Brazil lack artemisinin resistance-associated mutations in the kelch13 gene". Revista Da Sociedade Brasileira De Medicina Tropical Vol. 52 (2019): e20180225-e20180229. https://novaresearch.unl.pt/en/publications/3ec7c308-000f-4b7f-b8c6-2e67c4a5083a.
    10.1590/0037-8682-0225-2018
  15. Cravo P; Machado RB; Leite JA; Leda T; Suwanarusk R; Bittencourt N; Albrecht L; et al. "In silico epitope mapping and experimental evaluation of the Merozoite Adhesive Erythrocytic Binding Protein (MAEBL) as a malaria vaccine candidate.". Malaria journal (2018): http://europepmc.org/abstract/med/29316918.
    10.1186/s12936-017-2144-x
  16. Gomes, Andrea C.S.M.; Dos Santos, Samuel R.; Ribeiro, Maycon Carvalho; Pedro Cravo; Vieira, José Daniel Gonçalves José Daniel Gonçalves; De Souza, Keili M.C.; Amaral, André Corrêa. "Is there still room to explore cyclodextrin glycosyltransferase-producers in Brazilian biodiversity?". Anais da Academia Brasileira de Ciencias Vol. 90 n.º 2 (2018): p. 1473-1480. https://novaresearch.unl.pt/en/publications/09fc209e-1a82-4b74-8b85-a2eb316e8ff0.
    10.1590/0001-3765201820170670
  17. Lima, Marilia N. N.; Melo-Filho, Cleber C.; Cassiano, Gustavo C.; Neves, Bruno J.; Alves, Vinicius M.; Braga, Rodolpho C.; Cravo, Pedro V. L.; et al. "QSAR-Driven Design and Discovery of Novel Compounds With Antiplasmodial and Transmission Blocking Activities". Frontiers in Pharmacology 9 (2018): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000426694400001&KeyUID=WOS:000426694400001.
    10.3389/fphar.2018.00146
  18. Custodio, Jean M. F.; Michelini, Lidiane J.; de Castro, Mirian Rita C.; Vaz, Wesley F.; Neves, Bruno J.; Cravo, Pedro V. L.; Barreto, Francisco S.; et al. "Structural insights into a novel anticancer sulfonamide chalcone". New Journal of Chemistry 42 5 (2018): 3426-3434. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000426488900030&KeyUID=WOS:000426488900030.
    10.1039/c7nj03523c
  19. Andrade, Carolina Horta; Neves, Bruno Junior; Melo-Filho, Cleber Camilo; Rodrigues, Juliana; Silva, Diego Cabral; Braga, Rodolpho Campos; Cravo, Pedro Vitor Lemos. "In Silico Chemogenomics Drug Repositioning Strategies for Neglected Tropical Diseases.". Current medicinal chemistry (2018): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:29521204&KeyUID=MEDLINE:29521204.
    10.2174/0929867325666180309114824
  20. Cravo, Pedro. "Genomics strategy for rapid identification of mutations associated with drug resistance in malaria parasites". (2018): https://doi.org/10.25761/anaisihmt.30.
    https://doi.org/10.25761/anaisihmt.30
  21. GOMES,ANDREA C.S.M; SANTOS,SAMUEL R. DOS; RIBEIRO,MAYCON C.; CRAVO,PEDRO V.L.; VIEIRA,JOSÉ DANIEL G.; SOUZA,KEILI M.C. DE; AMARAL,ANDRE C.. "Is there still room to explore cyclodextrin glycosyltransferase-producers in Brazilian biodiversity?". (2018): http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000401473.
  22. Brasil P; Zalis MG; de Pina-Costa A; Siqueira AM; Júnior CB; Silva S; Areas ALL; et al. "Outbreak of human malaria caused by Plasmodium simium in the Atlantic Forest in Rio de Janeiro: a molecular epidemiological investigation.". The Lancet. Global health (2017): http://europepmc.org/abstract/med/28867401.
    10.1016/S2214-109X(17)30333-9
  23. Gomes MN; Muratov EN; Pereira M; Peixoto JC; Rosseto LP; Cravo PVL; Andrade CH; Neves BJ. "Chalcone Derivatives: Promising Starting Points for Drug Design.". Molecules (Basel, Switzerland) (2017): http://europepmc.org/abstract/med/28757583.
    10.3390/molecules22081210
  24. Campos DMB; Barbosa AP; Oliveira JA; Tavares GG; Cravo PVL; Ostermayer AL. "Human lagochilascariasis-A rare helminthic disease.". PLoS neglected tropical diseases (2017): http://europepmc.org/abstract/med/28640884.
    10.1371/journal.pntd.0005510
  25. Carvalho, Paulo S Jr; Custodio, Jean M F; Vaz, Wesley F; Cirilo, Cassio C; Cidade, Amanda F; Aquino, Gilberto L B; Campos, Dulcinea M B; et al. "Conformation analysis of a novel fluorinated chalcone.". Journal of molecular modeling 23 3 (2017): 97-97. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:28251413&KeyUID=MEDLINE:28251413.
    10.1007/s00894-017-3245-8
  26. Pedro Cravo. "Estratégia genómica para identificação rápida de mutações associadas a resistência a fármacos em parasitas de malária". Anais do Instituto de Higiene e Medicina Tropical 16 (2017): 65–68-65–68. https://novaresearch.unl.pt/en/publications/2f5ebd69-8de4-4d15-8e85-8396d35c76c8.
  27. Neves, Bruno Junior; Muratov, Eugene; Machado, Renato Beilner; Andrade, Carolina Horta; Cravo, Pedro Vitor Lemos. "Modern approaches to accelerate discovery of new antischistosomal drugs". Expert Opinion on Drug Discovery 11 6 (2016): 557-567. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000375839100004&KeyUID=WOS:000375839100004.
    10.1080/17460441.2016.1178230
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  72. Martinelli, A; Hunt, P; Fawcett, R; Cravo, PVL; Walliker, D; Carter, R. "An AFLP-based genetic linkage map of Plasmodium chabaudi chabaudi". Malaria Journal 4 (2005): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000227950700001&KeyUID=WOS:000227950700001.
    10.1186/1475-2875-4-11
  73. van Harten, S; Borges, S; Cravo, P; Cardoso, LA. "Contribution to the metabolic adaptation to food restriction in rabbits (preliminary results)". Journal of Biotechnology 118 (2005): S159-S160. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000231195200554&KeyUID=WOS:000231195200554.
  74. Ferreira ID; Nogueira F; Borges ST; do Rosário VE; Cravo P; Ferreira, ID; Nogueira, F; et al. "Is the expression of genes encoding enzymes of glutathione (GSH) metabolism involved in chloroquine resistance in Plasmodium chabaudi parasites?". Molecular and biochemical parasitology 136 1 (2004): 43-50. http://europepmc.org/abstract/med/15138066.
    10.1016/j.molbiopara.2004.02.008
  75. Cravo, P; Figueiredo, S; Nogueira, F; Lopes, D; Ferreira, ID; Ferreira, C; Gil, JP. "High frequency of the genetic polymorphisms associated with sulfadoxine-pyrimethamine resistance, among Plasmodium falciparum isolates from Sao Tome and Principe, West Africa". Annals of Tropical Medicine and Parasitology 98 3 (2004): 293-296. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000221387800009&KeyUID=WOS:000221387800009.
    10.1179/000349804225003262
  76. Hunt, P; Cravo, PVL; Donleavy, P; Carlton, JMR; Walliker, D. "Chloroquine resistance in Plasmodium chabaudi: are chloroquine-resistance transporter (crt) and multi-drug resistance (mdr1) orthologues involved?". Molecular and Biochemical Parasitology 133 1 (2004): 27-35. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000187807000003&KeyUID=WOS:000187807000003.
    10.1016/j.molbiopara.2003.08.010
  77. Gil, JP; Nogueira, F; Stromberg-Norklit, J; Lindberg, J; Carrolo, M; Casimiro, C; Lopes, D; et al. "Detection of atovaquone and Malarone (TM) resistance conferring mutations in Plasmodium falciparum cytochrome b gene (cytb)". Molecular and Cellular Probes 17 2-3 (2003): 85-89. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000183657600005&KeyUID=WOS:000183657600005.
    10.1016/S0890-8508(03)00006-9
  78. Cravo, PVL; Carlton, JMR; Hunt, P; Bisoni, L; Padua, RA; Walliker, D; Pedro Cravo; et al. "Genetics of mefloquine resistance in the rodent malaria parasite Plasmodium chabaudi". Antimicrobial Agents and Chemotherapy 47 2 (2003): 709-718. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000180646800040&KeyUID=WOS:000180646800040.
    10.1128/AAC.47.2.709-718.2003
  79. Dinora Lopes; Kanchana Rungsihirunrat; f nogueira; Aree Seugorn; José Pedro Gil; Virgilio E do Rosário; Pedro Cravo. "Molecular characterisation of drug-resistant Plasmodium falciparum from Thailand". Malaria Journal 1 (2002): 12-12. https://novaresearch.unl.pt/en/publications/e880044e-ddb4-4764-b202-bb9098a46af2.
  80. Lopes, D; Nogueira, F; Gil, JP; Ferreira, C; do Rosario, VE; Cravo, P. "pfcrt and pfmdr1 mutations and chloroquine resistance in Plasmodium falciparum from Sao Tome and Principe, West Africa". Annals of Tropical Medicine and Parasitology 96 8 (2002): 831-834. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000180745500010&KeyUID=WOS:000180745500010.
    10.1179/000349802125002284
  81. Ribeiro, O; Nogueira, F; Cravo, P; Gil, JP; do Rosario, V; Ribeiro, V. "Role of drug metabolizing enzymes in antimalarial drug resistance". Drug Metabolism Reviews 34 (2002): 74-74. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000178927200148&KeyUID=WOS:000178927200148.
  82. Cravo, P; Culleton, R; Hunt, P; Walliker, D; Mackinnon, MJ. "Antimalarial drugs clear resistant parasites from partially immune hosts". Antimicrobial Agents and Chemotherapy 45 10 (2001): 2897-2901. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000171154500035&KeyUID=WOS:000171154500035.
    10.1128/AAC.45.10.2897-2901.2001
  83. Carlton, JMR; Hayton, M; Cravo, PVL; Walliker, D. "Of mice and malaria mutants: unravelling the genetics of drug resistance using rodent malaria models". Trends in Parasitology 17 5 (2001): 236-242. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000169934200010&KeyUID=WOS:000169934200010.
    10.1016/S1471-4922(01)01899-2
  84. Thaithong, S; Ranford-Cartwright, LC; Siripoon, N; Harnyuttanakorn, P; Kanchanakhan, NS; Seugorn, A; Rungsihirunrat, K; Cravo, PVL; Beale, GH. "Plasmodium falciparum: Gene mutations and amplification of dihydrofolate reductase genes in parasites grown in vitro in presence of pyrimethamine". Experimental Parasitology 98 2 (2001): 59-70. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000170149200001&KeyUID=WOS:000170149200001.
    10.1006/expr.2001.4618
  85. Portela, MJ; Moreira, R; Valente, E; Constantino, L; Iley, J; Pinto, J; Rosa, R; Cravo, P; do Rosario, VE. "Dipeptide derivatives of primaquine as transmission-blocking antimalarials: Effect of aliphatic side-chain acylation on the gametocytocidal activity and on the formation of carboxyprimaquine in rat liver homogenates". Pharmaceutical Research 16 6 (1999): 949-955. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000080989200026&KeyUID=WOS:000080989200026.
    10.1023/A:1018922425551
Preprint
  1. Essoh, Anyse Pereira; Cassiano, Gustavo Capatti; Mandim, Filipa; Gomes, Isildo; Moura, Mónica; Medeiros, Márcia Melo; Cravo, Pedro; Romeiras, Maria Manuel. "Studies on the in vitro antiplasmodial activity of endemic and native plants from Cabo Verde". 2022. http://dx.doi.org/10.21203/rs.3.rs-1881844/v1.
Working paper
  1. Julyana Cerqueira Buery; Ana Maria Ribeiro de Castro Duarte; Filomena Euridice Carvalho de Alencar; C. Furieri; S.L. Mendes; A.C. Loss; C.R. Vicente; et al. 2020. "Detection of Plasmodium vivax in a liver sample of a howler-monkey: one evidence more in favour of the identity between Plasmodium simium and P. vivax". https://novaresearch.unl.pt/en/publications/fd6b95ad-64a6-4cf7-83b4-8b95d30eebdc.
    10.1101/2020.09.06.279869

Other

Other output
  1. Editorial letter. 2018. Pedro Cravo; Sandro Dutra E. Silva; Sandro Dutra E Silva. https://novaresearch.unl.pt/en/publications/e314a533-a7b4-471b-954b-3b8c54ac3e08.
    10.21664/2238-8869.2018v7i1.p01-08
  2. Carta editorial. 2018. Pedro Cravo; Sandro Dutra E. Silva. https://novaresearch.unl.pt/en/publications/dcb0e603-58e6-43e1-905d-97fe75309ffb.
    10.21664/2238-8869.2018v7i3
  3. Editorial. Dossiê "Tecnologias, Convergência Epistemológica da Complexidade". 2015. Antonio Pedro Costa; Luis Paulo Gonçalves Dos Reis; Pedro Cravo; Alexandre Cláudio Botazzo Delbem; Clarimar José Coelho. https://novaresearch.unl.pt/en/publications/7b8f7454-a7c5-4299-a08f-3bf77f5fa0e6.
    10.21664/2238-8869.2015v4i3.p11-15
  4. Genetic characterisation of Plasmodium falciparum populations in Sao Tome and Principe Islands, West Africa. 2007. José L. Vicente; Salgueiro, P; Arez, Ana Paula; Pedro Cravo; C. Ferreira; V. E. Rosario; Pinto J.. https://novaresearch.unl.pt/en/publications/77428540-a061-464d-acf6-c756d06d988b.
    10.1111/j.1365-3156.2007.01866.x
  5. Efflux pumps of antimalarial-resistant Plasmodium falciparum. 2004. f nogueira; Dinora Lopes; J P Gil; Virgilio Estólio do Rosário; Pedro Cravo. https://novaresearch.unl.pt/en/publications/2c7d3677-8608-489e-9307-22e809f3d4f8.
  6. Molecular markers of Plasmodium falciparum drug resistance in Thailand. Complete selection of pfcrt 76t by chloroquine. 2002. S Figueiredo; f nogueira; D Lopes; C Ferreira; Pedro Cravo; Virgilio Estólio do Rosário; J P Gil. https://novaresearch.unl.pt/en/publications/49bd3993-6ce2-465f-b5ca-97b776886257.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2018 Genomics and Bioinformatics in Drug Discovery Encontro Ciência 2018
ihmt (LISBON, Portugal)
2017 Genomewide strategies for rapid discovery of drug resistance-associated mutations: malaria First GHTM Antimicrobial Resistance Awareness Day. Instituto de Higiene e Medicina Tropical (IHMT)
Instituto de Higiene e Medicina Tropical/ Universidade Nova de Lisboa (LISBON, Portugal)
2017 Application of genomics and bioinformatics tools for rapid identification of new drugs and vaccines against tropical diseases II International Scientific Meeting of Instituto Evandro Chagas. Instituto Evandro Chagas
Instituto Evandro Chagas (Belém, Brazil)
2016 Drug Resistance in Malaria: A Genomics Perspective New Approaches to Drug Discovery against Tropical Diseases
Institute of Biology – University of Campinas (UNICAMP) (Campinas, Brazil)
2016 Identification and development of a subunit vaccine against plasmodium vivax through immunogenomics and heterologous expression in transgenic plants MEDTROP 2016 52º Congresso da Sociedade Brasileira de Medicina Tropical
Brazilian Society of Tropical Medicine (Fortaleza, Brazil)
2015 Using genomics towards more effective identification of new antimalarial drugs and vaccines Meeting of the São Paulo School of Advanced Sciences on Neglected Diseases Drug Discovery. Focus on Kinetoplastids.
LNBio, Campinas, Brasil (Campinas, Brazil)
2015 An overview of P. vivax drug resistance molecular markers XIV National Malaria Research Meeting
(Sao Paulo, Brazil)
2014 Genomics and a new paradigm to identify mechanisms of resistance to antimalarial drugs 3rd Meeting of Cytogenetics of Central Brazil. IX Workshop on Genetics at PUC Goiás
PUC Goias (Goiania, Brazil)
2013 Development of P. falciparum resistance to artemisinin derivatives XIII Reunião Nacional de Pesquisa em Malária.
Fundação de Medicina Tropical - Doutor Heitor Vieira Dourado (Manaus, Brazil)
2013 Antimalarial Drug Resistance: A Historical Perspective and Contemporary Threats XLIX Congress of the Brazilian Society of Tropical Medicine
Brazilian Society of Tropical Medicine (Campo Grande, Brazil)
2012 In silico screen for target similarity identifies several candidate drugs against proteins of the Plasmodium falciparum apicoplast XVIII International Congress on Tropical Medicine and Malaria
(Rio de Janeiro, Brazil)
2012 Studies on AP2 adaptor µ-chain, a new candidate molecular marker for artemisinin resistance in Plasmodium falciparum XVIII International Congress on Tropical Medicine and Malaria
(Rio de Janeiro, Brazil)
2011 Identification of artemisinin combination treatment (ACT) resistance mutations in malaria using post-genomic strategies XXI Brazilian Congress of Parasitology
(Sao Paulo, Brazil)
2011 Research and training in drug resistance, genomics and bioinformatics STRonGer Kick-off meeting.
Institut Pasteur de la Guyane, Cayenne (Cayenne, French Guiana)
2011 A new paradigm for rapid identification of antimalarial drug resistance mechanisms XXI Brazilian Congress of Parasitology
Brazilian Society of Tropical Medicine (Sao Paulo, Brazil)
2010 New genetic markers of resistance to artemisinin derivatives in malaria IV Meeting of Tropical Medicine of Portuguese-Speaking Countries and XLVI Congress of the Brazilian Society of Tropical Medicine
Brazilian Society of Tropical Medicine (Foz do Iguaçu, Brazil)
2010 Rapid discovery of molecular markers of drug resistance in malaria through genome-wide approaches Malaria Day Workshop. GSK
Glaxo-Smithklein (GSK) (Madrid, Spain)
2009 Malaria parasites can develop resistance to artemisinin-combination therapy (ACT) British Society for Parasitology Malaria Meeting
British Society for Parasitology (Edinburgh, United Kingdom)
2009 Evaluation of new molecular markers for artemisinin resistance in Plasmodium falciparum Meeting of the Plataforma Iberica de Malária. GSK-Tres Cantos
Glaxo-Smithklein (GSK) (Madrid, Spain)
2009 Plasmodium falciparum chromosome 1 and artemisinin resistance XLV Congress of the Brazilian Society of Tropical Medicine
Brazilian Society of Tropical Medicine (Olinda, Brazil)
2009 Artemisinin resistance in Plasmodium falciparum XI National Malaria Research Meeting and I Inter-Amazon Malaria Meeting
(Manaus, Brazil)
2007 An integrated laboratory and field-based approach to identify genotype-phenotype features of artemisinin resistance in Plasmodium falciparum COST B22 Working Group 5: Drug resistance in parasitic protozoa
Cost B22 (Montreal, Quebec, Canada)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2016 - 2018 Construction of a subunit vaccine against toxoplasmosis
Supervisor of Moisés Inácio
Universidade Federal de Goiás, Brazil
2014 - 2018 Identification of new antimalarial drugs through a chemogenomics strategy by repositioning and experimental validation
Supervisor of Juliana Rodrigues
Universidade Federal de Goiás, Brazil
2014 - 2018 Malaria: analysis of the evolution of natural populations of Plasmodium falciparum under pressure from artemisinin derivatives
Supervisor
 m (PhD)
Universidade Federal de Goiás, Brazil
2014 - 2016 Identification of vaccine epitopes by genomics towards the production of an antimalarial vaccine
Supervisor of Taizy Leda
Universidade Federal de Goiás, Brazil
2012 - 2016 Analysis of energy metabolism pathways of Leishmania brasiliensistowards finding enzyme inhibitors by virtual simulation in bioinformatics
Co-supervisor of Lourival Almeida Silva
Universidade Federal de Goiás Instituto de Patologia Tropical e Saúde Pública, Brazil
2012 - 2016 Study of the in vitro response of resistance to artemether and artesunate in samples of Plasmodium falciparum from the Amazon region
Co-supervisor of Adré Lisboa Áreas
Universidade Federal do Rio de Janeiro, Brazil
2011 - 2015 Early detection of the biological and genetic determinants of resistance to artemisinin-based combination therapy in malaria parasites
Supervisor
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2012 - 2014 Kdr gene genotyping and resistance analysis of Aedes aegypti larvae and adults from Goiânia, GO to insecticides
Co-supervisor of Francesca Chapadense
Universidade Federal de Goiás, Brazil
2010 - 2014 Identification of genes determining mefloquine resistance in malaria parasites
Supervisor of Sofia Trindade Borges
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2009 - 2013 Epidemiological studies and resistance to antimalarials in East Timor
Supervisor of Afonso de Almeida
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2009 - 2013 Leishmania infantum chemo-resistance: phenotypic and genotypic studies
Co-supervisor
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2010 - 2012 Evaluation of novel molecular markers for monitoring drug resistance in Plasmodium falciparum malaria
Supervisor of Gisela Henriques
Universidade de Lisboa Faculdade de Medicina, Portugal
2008 - 2012 Artemisinin and derivatives: susceptibility and fitness studies of resistant mutants in Plasmodium falciparum
Supervisor of Isabel Dinis Ferreira
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2008 - 2012 Severe malaria in children in Maputo: antimalarial resistance studies and analysis of genetic markers of the parasite and human host
Co-supervisor of Natércia Fernandes
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2009 - 2011 Analysis of the Gene Encoding a Ubiquitin-Specific Protease (UBP-1) in Plasmodium falciparum isolates from Africa and South America
Supervisor of Ana Isabel Reis
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2006 - 2010 Studies of new molecular markers for the evaluation of chemo-resistance in malaria caused by Plasmodium falciparum
Co-supervisor
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2006 - 2010 Antimalarial resistance in P. falciparum: interaction between the pfcrt and pfmdr1 genes
Co-supervisor of Dinora Lopes
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2007 - 2009 Development of an assay for high throughput antimalarial drug screening in vivo
Supervisor of Dusan Djokovic
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2007 - 2007 Analysis of the genetic profile of populations of P.vivax and P.falciparum in the State of Amazonas
Co-supervisor
Universidade Federal do Amazonas, Brazil
2005 - 2007 Studies of Plasmodium falciparum resistance to the antimalarial drugs chloroquine, amodiaquine, mefloquine and quinine in East Timor
Supervisor of Afonso de Almeida
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2006 - 2006 Identification of kdr mutations associated with pyrethroid insecticide resistance in the malaria vector Anopheles gambiae
Supervisor of Filipa Janeira
Universidade do Algarve, Portugal
2003 - 2005 Studies of avian malaria in Spheniscus demersus penguins at the Lisbon Zoo
Co-supervisor of Ana Catarina Alves
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2003 - 2005 Antifolate resistance studies in Plasmodium falciparum
Co-supervisor of Sofia Figueiredo
Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2004 - 2004 Study of chloroquine resistance in Plasmodium chabaudi
Supervisor of Sofia Trindade Borges
Universidade de Lisboa Faculdade de Ciências, Portugal
2003 - 2003 In vivo and in vitro susceptibility/resistance studies of Plasmodium falciparum to antimalarial drugs at the Pediatric Hospital of Luanda
Supervisor
Universidade Lusófona de Humanidades e Tecnologias, Portugal
2000 - 2000 Relationship between antimalarial drugs and immunity in Plasmodium chabaudi
Supervisor of Richard Culleton
The University of Edinburgh, United Kingdom

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2019/10 - 2019/11 Participation in the Keystone Symposia Congress "The Malaria Endgame: Innovation in Therapeutics, Vector Control and Public Health Tools (G1). Paper presentation: "Epirubicin as a potent antimalarial drug candidate identified by chemogenomics repurposing strategy"
Symposium
 Keystone Symposia Congress "The Malaria Endgame: Innovation in Therapeutics, Vector Control and Public Health Tools
Bill & Melinda Gates Foundation, United States

Committee member

Activity description
Role 		Institution / Organization
2015/02 - 2016/10 Coordinator of the Parasitology area of ¿¿the Commission of the Postgraduate Program in Tropical Medicine and Public Health (PPGMTSP) of the Institute of Tropical Pathology and Public Health/Federal University of Goiás, Brazil.
Coordinator
 Universidade Federal de Goiás, Brazil
2015/02 - 2016/10 Member of the Structuring Teaching Nucleus of the Bachelor's Degree in Biotechnology at the Federal University of Goiás (UFG), Goiânia, Brazil.
Member
 Universidade Federal de Goiás, Brazil
2015 - 2016 Vice-coordinator of the Bachelor's Degree in Biotechnology at the Federal University of Goiás, Goiânia, Brazil
Coordinator
 Universidade Federal de Goiás, Brazil

Consulting

Activity description Institution / Organization
2011 - 2014 Consultant for the consortium “STRonGer: Strengthening transdisciplinary research on infectious and emerging diseases in French Guiana: linking fieldwork, benchside and bedside”. STRonGer was funded by the EU FP7-REGPOT and coordinated by the Pasteur Institute of French Guiana. STRonGer was a consortium whose main objective was to assemble an effective task force in the management of infectious and emerging diseases in French Guiana. The consortium worked with specialist consultants from the UK, the Netherlands, Portugal and France. Institut Pasteur, France

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2018 - 2018 Teaching in the Curricular Unit “Malaria”, of the Master's Degree in Medical Parasitology, IHMT/ Universidade Nova de Lisboa (Mestrado) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2017 - 2018 Teaching in the Curricular Unit “Computational Biology and Bioinformatics”, 1st semester, 3rd Cycle of studies in Biomedical Sciences, 3rd Cycle of studies in Human Genetics and Infectious Diseases at Universidade Nova de Lisboa (Curso de doutoramento (conclusão de unidades curriculares)) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2015/02 - 2016/12 Teaching in the Bachelor's Degree in Biotechnology at the Federal University of Goiás, Goiânia, Brazil, from February 2015 to December 2016 (Bachelor) Universidade Federal de Goiás, Brazil
2014 - 2016 Coordination and Teaching of three editions of the Discipline “Principles and applications of genomics and bioinformatics for the study of infectious and parasitic diseases II” of the Postgraduate Program in Tropical Medicine and Public Health, IPTSP/UFG (Postgraduate Certificate) Universidade Federal de Goiás, Brazil
2013/08 - 2013/11 Organization, coordination and teaching of the Discipline: “Scientific Methodology”, of the Master in Society, Technology and Environment, Centro Universitário de Anápolis (UniEvangélica), Anápolis, Brazil. (Master) UniEVANGÉLICA Centro Universitário de Anápolis, Brazil
2012/06 - 2012/06 Organization, coordination and teaching of the short course: “Introduction to bioinformatics and genomics applied to the study of tropical parasites”. Department of International Health, Institute of Tropical Pathology and Public Health/UFG, Goiânia, Brazil (Postgraduate Certificate) Universidade Federal de Goiás, Brazil
2011/11 - 2011/11 Organization, coordination and teaching of the module “Biotechnology in malaria therapy” of the discipline “Biotechnology applied to parasitology” of the Bachelor's Degree in Biotechnology at the Institute of Tropical Pathology and Public Health/UFG, Goiânia, Brazil. (Postgraduate Certificate) Universidade Federal de Goiás, Brazil
2011/09 - 2011/09 Organization, coordination and teaching of the Postgraduate course “Genomics and Bioinformatics of Infectious Diseases” at the Faculty of Medicine of the University of São Paulo, São Paulo, Brazil (Postgraduate Certificate) Universidade de São Paulo Faculdade de Medicina, Brazil
2009/12 - 2010/01 Teaching in the module “Cellular and Molecular Biology” of the Master of Biomedical Sciences at the Institute of Hygiene and Tropical Medicine/Universidade Nova de Lisboa, Lisbon, Portugal (Mestrado) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2008/12 - 2009/01 Teaching in the module “Cellular and Molecular Biology” of the Master of Biomedical Sciences at the Institute of Hygiene and Tropical Medicine/Universidade Nova de Lisboa, Lisbon, Portugal (Mestrado) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2007/05 - 2007/05 Teaching in the module “Molecular Epidemiology” of the Master of Biomedical Sciences of the Institute of Hygiene and Tropical Medicine/Universidade Nova de Lisboa, Lisbon, Portugal (Mestrado)
2007/01 - 2007/01 Teaching in the module “Cellular and Molecular Biology” of the Master of Biomedical Sciences at the Institute of Hygiene and Tropical Medicine/Universidade Nova de Lisboa Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2006/04 - 2006/04 Organization and coordination of the Workshop: “Malaria and drug resistance”, as part of the Graduate Program in Basic and Applied Biology (GABBA Doctoral Program). Institute of Molecular and Cell Biology (IBMC), University of Porto (Doutoramento) Universidade do Porto, Portugal
2006/04 - 2006/04 Organization, coordination and teaching of the III WORKSHOP “Practical applications of Real-time PCR “. Molecular Biology department of the Institute of Hygiene and Tropical Medicine/New University of Lisbon (Curso de Especialização Tecnológica) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2005/09 - 2005/09 Organization, coordination and teaching of the practical course “Molecular Techniques And Bioinformatics In Malaria Research” (Postgraduate Certificate) Universidad de Antioquía, Colombia
2005/05 - 2005/05 Organization, coordination and teaching of the II WORKSHOP “Practical applications of PCR in real time“. UEI Molecular Biology of the Institute of Hygiene and Tropical Medicine/New University of Lisbon (Curso de Especialização Tecnológica) Universidade Nova de Lisboa Instituto de Higiene e Medicina Tropical, Portugal
2004/05 - 2004/05 Organization, coordination and teaching of the I WORKSHOP “Practical applications of PCR in real time“. UEI Molecular Biology of the Institute of Hygiene and Tropical Medicine/New University of Lisbon (Curso de Especialização Tecnológica)
2002/02 - 2002/02 Organization, coordination and teaching of the "Malaria parasite genetics/molecular biology" module in The 3rd Workshop of the African Malaria Vaccine Testing Network (AMVTN). Mozambique (Postgraduate Certificate)
Distinctions

Award

2005 Young Researcher Award
European Society of Clinical Microbiology and Infectious Diseases, Switzerland