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Catarina Alexandra Baptista Rodrigues. Completed the Doutoramento in DOUTORAMENTO EM QUÍMICA FARMACÊUTICA E TERAPÊUTICA in 2013/12/20 by Universidade de Lisboa Faculdade de Farmácia, Mestrado in Mestrado em Química in 2007 by Universidade de Lisboa Instituto Superior Técnico and Licenciatura in Licenciatura em Química in 2007 by Universidade de Lisboa Instituto Superior Técnico. Published 18 articles in journals. Has 2 section(s) of books. Organized 1 event(s). Co-supervised 1 MSc dissertation(s). Works in the area(s) of Exact Sciences with emphasis on Chemical Sciences with emphasis on Organic Chemistry. In their professional activities interacted with 91 collaborator(s) co-authorship of scientific papers. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: Two-photon absorption, Fluorescence, Oxazolone, Solvatochromism, Nonlinear emission, Push-pull; Metal catalysed transformations; Organic Chemistry; Photochemistry; New Metodologies for the valorization of Natural Products; Structural analysis by spectroscopic methods, HPLC and MS analysis; .
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Identification

Personal identification

Full name
Catarina Alexandra Baptista Rodrigues

Citation names

  • Rodrigues, Catarina

Author identifiers

Ciência ID
DE1F-1EFC-6772
ORCID iD
0000-0003-2899-8979

Telephones

Mobile phone
  • (0034) 640694074 (Personal)

Knowledge fields

  • Exact Sciences - Chemical Sciences - Organic Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Education
Degree Classification
2013/12/20
Concluded
 DOUTORAMENTO EM QUÍMICA FARMACÊUTICA E TERAPÊUTICA (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Synthesis and photochemical characterization of Multiphoton Absorbing Chromophores" (THESIS/DISSERTATION)
 Aprovada com Distinção e Louvor
2007
Concluded
 Mestrado em Química (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"Desenvolvimento de moléculas orgânicas libertadoras de monóxido de carbono (CO) para aplicação farmacêutica" (THESIS/DISSERTATION)
 16 valores
2007
Concluded
 Licenciatura em Química (Licenciatura)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"Não existe" (THESIS/DISSERTATION)
 14 valores
Affiliation

Science

Category
Host institution 		Employer
2013/10/01 - 2014/09/30 Researcher (Research) Universidade de Lisboa Faculdade de Farmácia, Portugal

Others

Category
Host institution 		Employer
2017/02/01 - 2019/01/31 Postdoctoral Research Fellow under supervision of Dr. Fernando Lopez, Dr. Moisés Gulías, and Prof. Dr. José Luis Mascareñas “Asymmetric functionalization of C(sp3)-H bonds catalyzed by metals.”. Centro Singular de Investigación en Química Biológica y Materiales Moleculares, Spain
2015/01/01 - 2017/01/31 Bolseira de Pós-Doutoramento financiada pela FCT ref. SFRH/BPD/100677/2014 “New synthetic routes for the valorization of easily accessible bio-renewable resources” Universidade de Lisboa Faculdade de Farmácia, Portugal
2009/07/01 - 2013/06/30 Bolseira de Doutoramento, ref. SFRH/BD/48145/2008, Thesis title: “Synthesis and photochemical characterization of Multiphoton Absorbing Chromophores” Universidade de Lisboa Faculdade de Farmácia, Portugal
2007/07/01 - 2009/06/30 Investigadora, Desenvolvimento e Optimização de Formulações para aplicação tópica de Compostos Orgânicos. Alfama, Lda. (http://www.alfama.com.pt/index.php), Portugal
2006/09/18 - 2007/06/30 Estágio curricular na área de Síntese Orgânica, Orientadores: Prof. Carlos Romão (Professor Catedrático ITQB/UNL), Dra. Marta Norton de Matos (Investigadora na Alfama, Lda.) e Prof. Carlos Afonso ( Alfama, Lda. (http://www.alfama.com.pt/index.php), Portugal
2005/11/18 - 2006/03/22 Colaboração com equipa de Investigação laboratorial em Síntese Orgânica, Referências fornecidas a pedido. Universidade de Lisboa Instituto Superior Técnico, Portugal
Projects

Grant

Designation Funders
2015/01 - 2017/01 New synthetic routes for the valorization of easily accessible bio-renewable resources
SFRH/BPD/100677/2014
Post-doc Fellow
Fundacao para a Ciencia e Tecnologia
2013/10/01 - 2014/09/30 Two-photon activated photochromic polymers
info:eu-repo/grantAgreement/FCT/3599-PPCDT/114367/PT
Research Fellow
Fundação para a Ciência e a Tecnologia
Concluded
2009/07 - 2013/06 New Combinatorial Approach for the Creation of Efficient Multiphoton Chromophores
SFRH/BD/48145/2008
PhD Student Fellow
Fundacao para a Ciencia e Tecnologia
Outputs

Publications

Book chapter
  1. Eliana Martins; Rodrigues, Catarina. "2.1.6. Conversion of alcohols into alkyl chlorides using cyanuric chloride". In Comprehensive Organic Chemistry Experiments for the Laboratory Classroom, 76. Royal Society of Chemistry, 2017.
  2. Rodrigues, Catarina; José M. G. Martinho; Carlos A. M. Afonso. "4.2.3.7. Synthesis of a biologically active oxazol-5(4H)-one via Erlenmeyer-Plöchl". In Comprehensive Organic Chemistry Experiments for the Laboratory Classroom, 391. Royal Society of Chemistry, 2017.
Journal article
  1. Sara R. Oliveira; Pedro A. Dionísio; Hugo Brito; Lídia Franco; Catarina A. B. Rodrigues; Rita C. Guedes; Carlos A. M. Afonso; Joana D. Amaral; Cecília M. P. Rodrigues. "Phenotypic screening identifies a new oxazolone inhibitor of necroptosis and neuroinflammation". Cell Death Discovery 5 1 (2018): https://doi.org/10.1038%2Fs41420-018-0067-0.
    10.1038/s41420-018-0067-0
  2. David F. Fernández; Catarina A. B. Rodrigues; Martín Calvelo; Moisés Gulías; José L. Mascareñas; Fernando López. "Iridium(I)-Catalyzed Intramolecular Cycloisomerization of Enynes: Scope and Mechanistic Course". ACS Catalysis 8 8 (2018): 7397-7402. https://doi.org/10.1021%2Facscatal.8b02139.
    10.1021/acscatal.8b02139
  3. Lídia A. S. Cavaca; Catarina A. B. Rodrigues; Svilen P. Simeonov; Rafael F. A. Gomes; Jaime A. S. Coelho; Gustavo P. Romanelli; Angel G. Sathicq; José J. Martínez; Carlos A. M. Afonso. "Valorization of Oleuropein via Tunable Acid-Promoted Methanolysis". ChemSusChem 11 14 (2018): 2300-2305. https://doi.org/10.1002%2Fcssc.201800980.
    10.1002/cssc.201800980
  4. Catarina A. B. Rodrigues; Iris Neto; Patricia Rijo; Carlos A. M. Afonso. "Synthesizing a Berberine Derivative and Evaluating Antimicrobial Activity To Reinforce with Students the Potential Significance of Small Chemical Structure Changes for Biological Systems". Journal of Chemical Education 95 3 (2018): 492-495. https://doi.org/10.1021%2Facs.jchemed.7b00458.
    10.1021/acs.jchemed.7b00458
  5. Eva Zupancic; Caterina Curato; Maria Paisana; Catarina Rodrigues; Ziv Porat; Ana S. Viana; Carlos A.M. Afonso; et al. "Rational design of nanoparticles towards targeting antigen-presenting cells and improved T cell priming". Journal of Controlled Release 258 (2017): 182-195. https://doi.org/10.1016%2Fj.jconrel.2017.05.014.
    10.1016/j.jconrel.2017.05.014
  6. Catarina A. B. Rodrigues; Antonio Misale; Florian Schiel; Nuno Maulide. "Direct synthesis of $\upgamma$-pyrones by electrophilic condensation of $\upbeta$-ketoesters". Org. Biomol. Chem. (2017):
    10.1039/c6ob01884j
  7. Jérémy Merad; Thomas Maier; Catarina A. B. Rodrigues; Nuno Maulide. "Synthesis of ¿-pyrones via decarboxylative condensation of ß-ketoacids". Monatshefte für Chemie - Chemical Monthly 148 1 (2016): 57-62. https://doi.org/10.1007%2Fs00706-016-1851-2.
    10.1007/s00706-016-1851-2
  8. Martin Berger; Rajan Chauhan; Catarina A. B. Rodrigues; Nuno Maulide. "Bridging C-H Activation: Mild and Versatile Cleavage of the 8-Aminoquinoline Directing Group". Chemistry - A European Journal 22 47 (2016): 16805-16808. https://doi.org/10.1002%2Fchem.201604344.
    10.1002/chem.201604344
  9. V. Sainz; C. Peres; T. Ciman; C. Rodrigues; A. S. Viana; C. A. M. Afonso; T. Barata; et al. "Optimization of protein loaded PLGA nanoparticle manufacturing parameters following a quality-by-design approach". RSC Advances 6 106 (2016): 104502-104512. https://doi.org/10.1039/C6RA19092H.
    10.1039/C6RA19092H
  10. Catarina A. B. Rodrigues; José M. G. Martinho; Carlos A. M. Afonso. "Synthesis of a Biologically Active Oxazol-5-(4H)-one via an Erlenmeyer–Plöchl Reaction". J. Chem. Educ. 92 9 (2015): 1543-1546. http://dx.doi.org/10.1021/ed500212t.
    10.1021/ed500212t
  11. Catarina A. B. Rodrigues; Raquel F. M. Frade; Inês S. Albuquerque; Maria J. Perry; Jiri Gut; Marta Machado; Philip J. Rosenthal; et al. "Targeting the Erythrocytic and Liver Stages of Malaria Parasites with s -Triazine-Based Hybrids". ChemMedChem 10 5 (2015): 883-890. http://dx.doi.org/10.1002/cmdc.201500011.
    10.1002/cmdc.201500011
  12. I. F. A. Mariz; F. Siopa; C. A. B. Rodrigues; C. A. M. Afonso; X. Chen; J. M. G. Martinho; E. M. S. Maçôas. "A 1,3,5-triazine based polymer as a nonlinear near-infrared antenna for two-photon activated volumetric optical memory devices". Journal of Materials Chemistry C 3 41 (2015): 10775-10782. https://doi.org/10.1039/C5TC02085A.
    10.1039/C5TC02085A
  13. Rodrigues, Catarina. "Development of Functionalized Nanoparticles for Vaccine Delivery to Dendritic Cells: a Mechanistic Approach". Nanomedicines (2014):
  14. Alexandre F. Trindade; Raquel F. M. Frade; Ermelinda M. S. Ma{\c{c}}{\^{o}}as; C{\'{a}}tia Gra{\c{c}}a; Catarina A. B. Rodrigues; Jos{\'{e}} M. G. Martinho; Carlos A. M. Afonso. "{\textquotedblleft}Click and go{\textquotedblright}: simple and fast folic acid conjugation". Org. Biomol. Chem. 12 20 (2014): 3181-3181. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000335336800006&KeyUID=WOS:000335336800006.
    10.1039/c4ob00150h
  15. Catarina A. B. Rodrigues; Cátia Graça; Ermelinda Maçôas; Alexander Fedorov; Carlos A. M. Afonso; José M. G. Martinho. "Excited-State Proton Transfer of Fluorescein Anion as an Ionic Liquid Component". J. Phys. Chem. B 117 45 (2013): 14108-14114. http://dx.doi.org/10.1021/jp408616r.
    10.1021/jp408616r
  16. Catarina A.B. Rodrigues; In{\^{e}}s F.A. Mariz; Ermelinda M.S. Ma{\c{c}}{\^{o}}as; Carlos A.M. Afonso; Jos{\'{e}}. M.G. Martinho. "Unsaturated oxazolones as nonlinear fluorophores". Dyes and Pigments 99 3 (2013): 642-652. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000327560200017&KeyUID=WOS:000327560200017.
    10.1016/j.dyepig.2013.06.012
  17. Rodrigues, Catarina A.B.; Mariz, Inês F.A.; Maçôas, Ermelinda M.S.; Afonso, Carlos A.M.; Martinho, José M.G.. "Two-photon absorption properties of push–pull oxazolones derivatives". Dyes and Pigments 95 3 (2012): 713-722. http://dx.doi.org/10.1016/j.dyepig.2012.06.005.
    10.1016/j.dyepig.2012.06.005
  18. Catarina A.B. Rodrigues; Marta Norton de Matos; Bruno M.H. Guerreiro; Ana M.L. Gonçalves; Carlos C. Romão; Carlos A.M. Afonso. "Water as efficient medium for mild decarbonylation of tertiary aldehydes". Tetrahedron Letters 52 22 (2011): 2803-2807. http://dx.doi.org/10.1016/j.tetlet.2011.03.012.
    10.1016/j.tetlet.2011.03.012
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2015/12/03 “Antimalarial activity of s-Triazine based hybrids in both erythrocytic and liver stages.” 11ENQO-4EQT, 11º Encontro Nacional de Química Orgânica- 4º Encontro de Química Terapêutica
Universidade do Porto (Porto, Portugal)
2014/04/29 “Targeting the erythrocytic and liver stages of malaria parasite with s-triazine-based hybrids” 4PYCheM, 4th Portuguese Young Chemists Meeting
Universidade de Coimbra (Coimbra, Portugal)
2013/07/18 “Photochemical tools for biological applications - Fluorescent Probes and Sensors” 5th iMed Postgraduate Students Seminar
Faculdade de Farmácia, Universidade de Lisboa (Lisboa, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2016/07 - 2017/09 “New Synthetic Routes for the Valorization of Easily Accessible Bio-renewable Resources”
Co-supervisor
 Master Thesis in Bioorganic Chemistry (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2013/09/04 - 2013/09/06 10ENQO-1SLB, 10ºEncontro Nacional de Química Orgânica-1ºSimposio Luso-Brasileiro (http://10enqo.eventos.chemistry.pt/?ver=committees) (2013/09/04 - 2013/09/06)
Conference (Member of the Organising Committee)
 Universidade de Lisboa Faculdade de Farmácia, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2015/09 - 2015/12 Teacher of laboratory classes in “Pharmaceutical Chemistry II”, 4th year students of integrated Master in Pharmaceutical Sciences - 3 hours/week “Pharmaceutical Chemistry II” (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2013/03 - 2013/06 Teacher of laboratory classes in “Organic Chemistry I”, 1st year students of integrated Master in Pharmaceutical Sciences - 3 hours/week. Organic Chemistry I (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal

Mentoring / Tutoring

Topic Student name
2017/10 - 2018/06 “Catálisis enantioselectiva de iridio para la síntesis de sistemas cíclicos con múltiples estereocentros cuaternarios” Ignacio Godoy Calvo
2016/09 - 2016/12 Síntese de derivados de sais de piridinio com atividade biológica Miguel Antunes Ferreira Bárbara
2016/03 - 2016/07 Synthesis of berberine derivatives via cross-coupling reactions Eliana Martins
2015/09 - 2015/12 “Synthesis of biological active berberine derivatives” Eliana Martins
2012/09 - 2012/12 Síntese de moléculas para sensores - Triazinas e oxazolonas Maria Atanásio
2012/03 - 2012/06 “Síntese de sondas orgânicas para detecção de metais em sistemas biológicos” Andrea Pardo Latorre