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Identification

Personal identification

Full name
Margarida Cuco Quaresma

Citation names

  • Quaresma, Margarida C

Author identifiers

Ciência ID
DE1B-37F9-3DB7
ORCID iD
0000-0001-7978-4685

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Education
Degree Classification
2016/01 - 2022/04
Concluded
 Biology (Doutoramento)
Major in Systems Biology
Universidade de Lisboa Faculdade de Ciências, Portugal
"Role of CFTR in epithelial to mesenchymal transition (EMT) by functional genomics" (THESIS/DISSERTATION)
2013 - 2015
Concluded
 Biochemistry (Mestrado)
Major in Medical Biochemistry
Universidade de Lisboa Faculdade de Ciências, Portugal
"Effect of TGF-ß Signalling on CFTR Protein: Consequences for Epithelial Differentiation in Cystic Fibrosis" (THESIS/DISSERTATION)
2010 - 2013
Concluded
 Biochemistry (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
Affiliation

Science

Category
Host institution 		Employer
2014/09 - 2021/11 Researcher (Research) Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
2017/11 - 2018/05 Visiting Researcher (Research) European Molecular Biology Laboratory, Germany
2012/10 - 2013/07 Research Trainee (Research) Universidade de Lisboa Centro de Química e Bioquímica, Portugal
Outputs

Publications

Journal article
  1. Quaresma, Margarida C; Botelho, Hugo M; Pankonien, Ines; Rodrigues, Cláudia S; Pinto, Madalena C; Costa, Pau R; Duarte, Aires; Amaral, Margarida D. "Exploring YAP1-centered networks linking dysfunctional CFTR to epithelial-mesenchymal transition". Life Science Alliance 5 9 (2022): e202101326. http://dx.doi.org/10.26508/lsa.202101326.
    10.26508/lsa.202101326
  2. Ines Pankonien; Margarida C. Quaresma; Cláudia S. Rodrigues; Margarida D. Amaral. "CFTR, Cell Junctions and the Cytoskeleton". International Journal of Molecular Sciences (2022): https://doi.org/10.3390/ijms23052688.
    10.3390/ijms23052688
  3. "Synergy in Cystic Fibrosis Therapies: Targeting SLC26A9". International Journal of Molecular Sciences 22 23 (2021): 13064-13064. http://dx.doi.org/10.3390/ijms222313064.
    10.3390/ijms222313064
  4. Amaral, Margarida; Quaresma, Margarida C; Pankonien, Ines. "What Role Does CFTR Play in Development, Differentiation, Regeneration and Cancer?". International Journal of Molecular Sciences 21 9 (2020): 3133.
    Open access • Published
  5. Quaresma, Margarida C; Pankonien, Ines; Clarke, Luka A; Silva, Iris A.L.; Railean, Violeta; Doušová, Tereza; Fuxe, Jonas; Amaral, Margarida. "Mutant CFTR Drives TWIST1 Mediated Epithelial-Mesenchymal Transition". Cell Death and Disease (2020):
    Under revision
  6. Simões, Filipa B; Quaresma, Margarida C; Clarke, Luka A; Silva, Iris AL; Pankonien, Ines; Railean, Violeta; Kmit, Arthur; Amaral, Margarida D. "TMEM16A chloride channel does not drive mucus production". Life Science Alliance 2 6 (2019): e201900462. http://dx.doi.org/10.26508/lsa.201900462.
    10.26508/lsa.201900462
  7. Lérias, Joana R.; Pinto, Madalena C.; Botelho, Hugo M.; Awatade, Nikhil T.; Quaresma, Margarida C.; Silva, Iris A.L.; Wanitchakool, Podchanart; et al. "A novel microscopy-based assay identifies extended synaptotagmin-1 (ESYT1) as a positive regulator of anoctamin 1 traffic". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1865 2 (2018): 421-431. http://dx.doi.org/10.1016/j.bbamcr.2017.11.009.
    10.1016/j.bbamcr.2017.11.009
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2019/11 Partial Epithelial to Mesenchymal Transition (EMT) in CF Cells: CF as an Epithelial Differentiation Disorder 33rd Annual North American Cystic Fibrosis Conference (NACFC)
(Nashville, United States)
2017/02 Role of CFTR in epithelial mesenchymal transition (EMT) by functional genomics Chemistry and Biochemistry Postgraduate Students Meeting
Universidade de Lisboa Faculdade de Ciências (Lisboa, Portugal)

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2019/03 - Current Poster presentation: Partial Epithelial to Mesenchymal Transition (EMT) in CF: CF as an Epithelial Differentiation Disorder
Conference
 16th ECFS Basic Science Conference – New Frontiers in Basic Science of Cystic Fibrosis
2018/09 - Current Poster presentation: Role of CFTR in Epithelial-Mesenchymal Transition (EMT) by Functional Genomics
Conference
 9th Meeting on Signal Transduction – SINAL 2018
2018/04 - Current Integrating systems biology: From networks to mechanisms to models (EMBO workshop)
Workshop
 Integrating systems biology: From networks to mechanisms to models
European Molecular Biology Laboratory, Germany
2017/03 - Current Poster presentation: Role of CFTR in the maintenance of airway epithelial cell differentiation
Conference
 14th ECFS Basic Science Conference – New Frontiers in Basic Science of Cystic Fibrosis
Distinctions

Award

2019 Best Oral Presentation Award at ECFS Basic Science Conference 2019, sponsored by Bob Emmelkamp. Travel Award to participate at North-American CF Conference.

Other distinction

2019 Student helper position at the 16th ECFS Basic Science Conference
European Cystic Fibrosis Society, Denmark
2017 Christian Boulin Fellowship
European Molecular Biology Laboratory, Germany