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Roland Bücker. Completed the Doktor (PhD) in AG Mucosa/Helicobacter, Medical Faculty in 2007/10/18 by Ruhr-Universität Bochum Institut für Physiologie. Is Principal Investigator in Charité Universitätsmedizin Berlin Medizinische Klinik für Gastroenterologie Infektiologie und Rheumatologie einschliesslich Arbeitsbereich Ernährungs and Associate Professor in CharitéCentrum 13 Innere Medizin mit Gastroenterologie und Nephrologie. Published 40 articles in journals. Has 2 section(s) of books. Supervised 4 PhD thesis(es). Has received 1 awards and/or honors. Participates and/or participated as Principal investigator in 2 project(s). Works in the area(s) of Medical and Health Sciences with emphasis on Health Sciences with emphasis on Infectious Diseases, Medical and Health Sciences with emphasis on Basic Medicine with emphasis on Physiology, Natural sciences with emphasis on Biological Sciences with emphasis on Molecular Biology and Natural sciences with emphasis on Biological Sciences with emphasis on Microbiology.
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Identification

Personal identification

Full name
Roland Bücker

Citation names

  • Bücker, Roland

Author identifiers

Ciência ID
DD13-FF6F-939B
ORCID iD
0000-0002-1345-4146

Telephones

Telephone
  • (+49) 30450 Ext.: 514548 (Professional)

Addresses

  • Hindenburgdamm 30, 12203, Berlin, Berlin, Germany (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Health Sciences - Infectious Diseases
  • Medical and Health Sciences - Basic Medicine - Physiology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Microbiology

Languages

Language Speaking Reading Writing Listening Peer-review
German (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2003/07/01 - 2007/10/18
Concluded
 AG Mucosa/Helicobacter, Medical Faculty (Doktor (PhD))
Ruhr-Universität Bochum Institut für Physiologie, Germany
"The acute colonization of the stomach mucus by Helicobacter pylori in vivo - the first step of infection" (THESIS/DISSERTATION)
Affiliation

Science

Category
Host institution 		Employer
2007/10/21 - Current Principal Investigator (Research) Charité Universitätsmedizin Berlin Medizinische Klinik für Gastroenterologie Infektiologie und Rheumatologie einschliesslich Arbeitsbereich Ernährungs, Germany
Charité Universitätsmedizin Berlin, Germany

Teaching in Higher Education

Category
Host institution 		Employer
2015/07/13 - Current Associate Professor (University Teacher) CharitéCentrum 13 Innere Medizin mit Gastroenterologie und Nephrologie, Germany
Charité Universitätsmedizin Berlin, Germany
Projects

Grant

Designation Funders
2020/12/01 - Current STED superresolution confocal microscope
INST 335/753-1
Principal investigator
Deutsche Forschungsgemeinschaft, Germany
Ongoing
2017/09/15 - Current Strengthening the intestinal barrier in Campylobacter infection, BMBF project Zoonosis Network
01KI2007D
Principal investigator
Charité Universitätsmedizin Berlin Campus Benjamin Franklin, Germany
 Bundesministerium für Bildung und Forschung Dienststelle Berlin
Ongoing

Other

Designation Funders
2021/08/24 - Current Involved researcher im DFG Graduate School GRK 2318
DFG GRK 2318
Supervisor
Charité Universitätsmedizin Berlin Institut für Klinische Physiologie, Germany
Ongoing
Outputs

Publications

Book chapter
  1. Lobo de Sá, Fábia Daniela; Schulzke, Jörg-Dieter; Bücker, Roland. "Diarrheal Mechanisms and the Role of Intestinal Barrier Dysfunction in Campylobacter Infections". In Current Topics in Microbiology and Immunology, 203-231. Springer International Publishing, 2021.
    10.1007/978-3-030-65481-8_8
  2. Bücker, Roland; Schumann, Michael; Amasheh, Salah; Schulzke, Jörg-Dieter. "Claudins in Intestinal Function and Disease". In Current Topics in Membranes, 195-227. Elsevier, 2010.
    10.1016/s1063-5823(10)65009-0
Conference poster
  1. Mateus, Cristiana; Domingues, Fernanda; Bücker, Roland; Oleastro, Mónica; Ferreira, Susana. "Effect of htrA gene in the pathogenicity of Aliarcobacter butzleri". Paper presented in Microbiotec’23 - Congress of Microbiology and Biotechnology 2023, 2023.
  2. Mateus, Cristiana; Domingues, Fernanda; Bücker, Roland; Oleastro, Mónica; Ferreira, Susana. "Role of htrA gene in the pathogenicity of Aliarcobacter butzleri". Paper presented in XVIII International CICS-UBI Symposium, 2023.
  3. Mateus, Cristiana; Maia, Cláudio J. B.; Domingues, Fernanda; Bücker, Roland; Oleastro, Mónica; Ferreira, Susana. "Evaluation of Aliarcobacter butzleri response in the presence of bile salts". Paper presented in Encontro Ciência 22, 2022.
  4. Mateus, Cristiana; Maia, Cláudio J. B.; Domingues, Fernanda C.; Bücker, Roland; Oleastro, Mónica; Ferreira, Susana. "Evaluation of Aliarcobacter butzleri response to bile salts". Paper presented in Microbiotec 21 – Congress of Microbiology and Biotechnology 2021, 2021.
Journal article
  1. Heimesaat MM; Mousavi S; Lobo de Sá FD; Peh E; Schulzke JD; Bücker R; Kittler S; Bereswill S. "Oral curcumin ameliorates acute murine campylobacteriosis.". Frontiers in Immunology (2024): https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1363457/pdf.
    10.3389/fimmu.2024.1363457
  2. Karem Awad; Christian Barmeyer; Christian Bojarski; Oliver Nagel; In-Fah M. Lee; Michal Ruth Schweiger; Jörg-Dieter Schulzke; Roland Bücker. "Epithelial Barrier Dysfunction in Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) via Downregulation of Claudin-1". Cells (2023): https://www.mdpi.com/2073-4409/12/24/2846.
    10.3390/cells12242846
  3. Martina Schneemann; Lucas Heils; Verena Moos; Franziska Weiß; Susanne M Krug; January Weiner; Dieter Beule; et al. "A Colonic Organoid Model Challenged with the Large Toxins of Clostridioides difficile TcdA and TcdB Exhibit Deregulated Tight Junction Proteins". Toxins (2023): https://www.mdpi.com/2072-6651/15/11/643.
    10.3390/toxins15110643
  4. Cristiana Mateus; Maia CJ; Domingues, F.C.; Roland Bücker; Mónica Oleastro; Susana Ferreira. "Evaluation of Bile Salts on the Survival and Modulation of Virulence of Aliarcobacter butzleri". Antibiotics (2023): https://www.mdpi.com/2079-6382/12/9/1387.
    10.3390/antibiotics12091387
  5. Sholpan Omarova; Karem Awad; Verena Moos; Christoph Püning; Greta Gölz; Jörg-Dieter Schulzke; Roland Bücker. "Intestinal Barrier in Post-Campylobacter jejuni Irritable Bowel Syndrome". Biomolecules (2023): https://www.mdpi.com/2218-273X/13/3/449.
    10.3390/biom13030449
  6. Lucas Heils; Martina Schneemann; Ralf Gerhard; Jörg-Dieter Schulzke; Roland Bücker. "CDT of Clostridioides difficile Induces MLC-Dependent Intestinal Barrier Dysfunction in HT-29/B6 Epithelial Cell Monolayers". Toxins (2023): https://www.mdpi.com/2072-6651/15/1/54.
    10.3390/toxins15010054
  7. Karem Awad; Christian Barmeyer; Christian Bojarski; Oliver Nagel; In-Fah M. Lee; Michal Ruth Schweiger; Jörg-Dieter Schulzke; Roland Bücker. "Impaired Intestinal Permeability of Tricellular Tight Junctions in Patients with Irritable Bowel Syndrome with Mixed Bowel Habits (IBS-M)". Cells (2023): https://www.mdpi.com/2073-4409/12/2/236.
    10.3390/cells12020236
  8. Hader H; Hering NA; Schulzke JD; Bücker R; Rosenthal R. "Myrrh protects against IL-13-induced epithelial barrier breakdown in HT-29/B6 cells.". Frontiers in Pharmacology (2023): https://www.frontiersin.org/articles/10.3389/fphar.2023.1301800/pdf?isPublishedV2=False.
    10.3389/fphar.2023.1301800
  9. Martins, Rodrigo; Mateus, Cristiana; Domingues, Fernanda; Bücker, Roland; Oleastro, Mónica; Ferreira, Susana. "Effect of Atmospheric Conditions on Pathogenic Phenotypes of Arcobacter butzleri". Microorganisms 10 12 (2022): 2409. http://dx.doi.org/10.3390/microorganisms10122409.
    10.3390/microorganisms10122409
  10. Kaak JL; Lobo de Sá FD; Jerrold R Turner; Schulzke JD; Roland Bücker. "Unraveling the intestinal epithelial barrier in cyanotoxin microcystin-treated Caco-2 cell monolayers.". Annals of the New York Academy of Sciences (2022): https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/nyas.14870.
    10.1111/nyas.14870
  11. Fábia Lobo; Steffen Backert; Praveen Kumar Nattramilarasu; Soraya Mousavi; Geoffrey Sandle; Stefan Bereswill; Markus Heimesaat; Jörg-Dieter Schulzke; Roland Bücker. "Vitamin D Reverses Disruption of Gut Epithelial Barrier Function Caused by Campylobacter jejuni". International Journal of Molecular Sciences (2021): https://www.mdpi.com/1422-0067/22/16/8872.
    10.3390/ijms22168872
  12. Emanuel Schulz; Michael Schumann; Martina Schneemann; Violaine Dony; Anja Fromm; Oliver Nagel; Jörg-Dieter Schulzke; Roland Bücker. "Escherichia coli Alpha-Hemolysin HlyA Induces Host Cell Polarity Changes, Epithelial Barrier Dysfunction and Cell Detachment in Human Colon Carcinoma Caco-2 Cell Model via PTEN-Dependent Dysregulation of Cell Junctions". Toxins (2021): https://www.mdpi.com/2072-6651/13/8/520.
    10.3390/toxins13080520
  13. Praveen Kumar Nattramilarasu; Fábia Lobo; Jörg-Dieter Schulzke; Roland Bücker. "Immune-Mediated Aggravation of the Campylobacter concisus-Induced Epithelial Barrier Dysfunction". International Journal of Molecular Sciences (2021): https://www.mdpi.com/1422-0067/22/4/2043.
    10.3390/ijms22042043
  14. Lobo de Sá FD; Heimesaat MM; Bereswill S; Nattramilarasu PK; Schulzke JD; Bücker R. "Resveratrol Prevents Campylobacter jejuni -Induced Leaky gut by Restoring Occludin and Claudin-5 in the Paracellular Leak Pathway.". Frontiers in Pharmacology (2021):
    10.3389/fphar.2021.640572
  15. Markus Heimesaat; Soraya Mousavi; Ulrike Escher; Fábia Lobo; Elisa Peh; Jörg-Dieter Schulzke; Sophie Kittler; Roland Bücker; Stefan Bereswill. "Resveratrol Alleviates Acute Campylobacter jejuni Induced Enterocolitis in a Preclinical Murine Intervention Study". Microorganisms (2020): https://www.mdpi.com/2076-2607/8/12/1858.
    10.3390/microorganisms8121858
  16. Bücker, Roland. "Contribution of Epithelial Apoptosis and Subepithelial Immune Responses in Campylobacter jejuni Induced Barrier Disruption.". Frontiers in microbiology (2020): https://europepmc.org/articles/PMC7067706.
    10.3389/fmicb.2020.00344
  17. Bücker, Roland. "Zinc prevents intestinal epithelial barrier dysfunction induced by alpha-hemolysin-producing Escherichia coli 536 infection in porcine colon.". Veterinary Microbiology (2020): https://doi.org/10.1016/j.vetmic.2020.108632.
    10.1016/j.vetmic.2020.108632
  18. Bücker, Roland. "Campylobacter concisus Impairs Sodium Absorption in Colonic Epithelium via ENaC Dysfunction and Claudin-8 Disruption.". International journal of molecular sciences (2020): https://europepmc.org/articles/PMC7013563.
    10.3390/ijms21020373
  19. Nina Alexandra Hering; Anja Fromm; Roland Bücker; Gregor Gorkiewicz; Ellen L. Zechner; Christoph Högenauer; Michael Fromm; Jörg-Dieter Schulzke; Hanno Troeger. "Tilivalline- and Tilimycin-Independent Effects of Klebsiella oxytoca on Tight Junction-Mediated Intestinal Barrier Impairment". International Journal of Molecular Sciences (2019): https://www.mdpi.com/1422-0067/20/22/5595.
    10.3390/ijms20225595
  20. Fábia Lobo; Eduard Butkevych; Praveen Kumar Nattramilarasu; Anja Fromm; Soraya Mousavi; Verena Moos; Julia C. Golz; et al. "Curcumin Mitigates Immune-Induced Epithelial Barrier Dysfunction by Campylobacter jejuni". International Journal of Molecular Sciences (2019): https://www.mdpi.com/1422-0067/20/19/4830.
    10.3390/ijms20194830
  21. Bücker, Roland. "Campylobacter jejuni enters gut epithelial cells and impairs intestinal barrier function through cleavage of occludin by serine protease HtrA.". Gut pathogens (2019): https://europepmc.org/articles/PMC6373145.
    10.1186/s13099-019-0283-z
  22. Mousavi S; Lobo de Sá FD; Schulzke JD; Bücker R; Bereswill S; Heimesaat MM. "Vitamin D in Acute Campylobacteriosis-Results From an Intervention Study Applying a Clinical Campylobacter jejuni Induced Enterocolitis Model.". Frontiers in Immunology (2019):
    10.3389/fimmu.2019.02094
  23. Bücker, Roland. "Establishment of a Mucin Secreting Cell Line Cx-03 from an Uterine Carcino Sarcoma.". Pharmaceutical research (2018): https://doi.org/10.1007/s11095-018-2533-z.
    10.1007/s11095-018-2533-z
  24. Bücker, Roland. "In Colon Epithelia, Clostridium perfringens Enterotoxin Causes Focal Leaks by Targeting Claudins Which are Apically Accessible Due to Tight Junction Derangement.". The Journal of infectious diseases (2017): https://doi.org/10.1093/infdis/jix485.
    10.1093/infdis/jix485
  25. Bücker, Roland. "Campylobacter jejuni impairs sodium transport and epithelial barrier function via cytokine release in human colon.". Mucosal immunology (2017): https://doi.org/10.1038/mi.2017.78.
    10.1038/mi.2017.78
  26. Bücker, Roland. "Giardia's Epithelial Cell Interaction In Vitro: Mimicking Asymptomatic Infection?". Frontiers in cellular and infection microbiology (2017): https://europepmc.org/articles/PMC5622925.
    10.3389/fcimb.2017.00421
  27. Bücker, Roland. "Gastrointestinal Tract As Entry Route for Hantavirus Infection.". Frontiers in microbiology (2017): https://europepmc.org/articles/PMC5596106.
    10.3389/fmicb.2017.01721
  28. Bücker, Roland. "Campylobacter jejuni impairs sodium transport and epithelial barrier function via cytokine release in human colon.". Mucosal immunology (2017): https://doi.org/10.1038/mi.2017.66.
    10.1038/mi.2017.66
  29. Bücker, Roland. "Campylobacter fetus impairs barrier function in HT-29/B6 cells through focal tight junction alterations and leaks.". Annals of the New York Academy of Sciences (2017): https://doi.org/10.1111/nyas.13406.
    10.1111/nyas.13406
  30. Bücker, Roland. "Zinc treatment is efficient against Escherichia coli a-haemolysin-induced intestinal leakage in mice.". Scientific reports (2017): https://europepmc.org/articles/PMC5374507.
    10.1038/srep45649
  31. Bücker, Roland. "Arcobacter butzleri isolates exhibit pathogenic potential in intestinal epithelial cell models.". Journal of applied microbiology (2015): https://doi.org/10.1111/jam.12979.
    10.1111/jam.12979
  32. Bücker, Roland. "Yersinia enterocolitica Affects Intestinal Barrier Function in the Colon.". The Journal of infectious diseases (2015): https://doi.org/10.1093/infdis/jiv571.
    10.1093/infdis/jiv571
  33. Bücker, Roland. "Interleukin-13 affects the epithelial sodium channel in the intestine by coordinated modulation of STAT6 and p38 MAPK activity.". The Journal of physiology (2015): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704517.
    10.1113/jp271156
  34. Buecker, Roland; Schulz, Emanuel; Guenzel, Dorothee; Bojarski, Christian; Lee, In-Fah M.; John, Lena J.; Wiegand, Stephanie; et al. "alpha-Haemolysin of Escherichia coli in IBD: a potentiator of inflammatory activity in the colon". Gut 63 12 (2014): 1893-1901. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000343938200012&KeyUID=WOS:000343938200012.
    10.1136/gutjnl-2013-306099
  35. Schneditz, Georg; Rentner, Jana; Roier, Sandro; Pletz, Jakob; Herzog, Kathrin A. T.; Buecker, Roland; Troeger, Hanno; et al. "Enterotoxicity of a nonribosomal peptide causes antibiotic-associated colitis". Proceedings of the National Academy of Sciences of the United States of America 111 36 (2014): 13181-13186. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000341625600052&KeyUID=WOS:000341625600052.
    10.1073/pnas.1403274111
  36. Hering, N. A.; Richter, J. F.; Fromm, A.; Wieser, A.; Hartmann, S.; Guenzel, D.; Buecker, R.; et al. "TcpC protein from E. coli Nissle improves epithelial barrier function involving PKC zeta and ERK1/2 signaling in HT-29/B6 cells". Mucosal Immunology 7 2 (2014): 369-378. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000331948300017&KeyUID=WOS:000331948300017.
    10.1038/mi.2013.55
  37. Yu, Chao; Achazi, Katharina; Moeller, Lars; Schulzke, Joerg D.; Niedrig, Matthias; Buecker, Roland. "Tick-Borne Encephalitis Virus Replication, Intracellular Trafficking, and Pathogenicity in Human Intestinal Caco-2 Cell Monolayers". Plos One 9 5 (2014): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000336653300054&KeyUID=WOS:000336653300054.
    10.1371/journal.pone.0096957
  38. Buecker, R.; Schulz, E.; Troeger, H.; Schulzke, J.. "E. coli alpha-hemolysin as potential mediator of inflammatory activities in colitis". International Journal of Medical Microbiology 303 (2013): 25-25. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000331497600083&KeyUID=WOS:000331497600083.
  39. Bratz, Katharina; Buecker, Roland; Goelz, Greta; Zakrzewski, Silke S.; Janczyk, Pawel; Noeckler, Karsten; Alter, Thomas. "Experimental infection of weaned piglets with Campylobacter coli - Excretion and translocation in a pig colonisation trial". Veterinary Microbiology 162 1 (2013): 136-143. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000315002800016&KeyUID=WOS:000315002800016.
    10.1016/j.vetmic.2012.08.016
  40. Nielsen, H. L.; Engberg, J.; Ejlertsen, T.; Buecker, R.; Nielsen, H.. "Short-term and medium-term clinical outcomes of Campylobacter concisus infection". Clinical Microbiology and Infection 18 11 (2012): E459-E465. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000310069400004&KeyUID=WOS:000310069400004.
    10.1111/j.1469-0691.2012.03990.x
  41. Bratz, K.; Goelz, G.; Alter, T.; Buecker, R.; Janczyk, P.; Noeckler, K.. "Effects of dietary zinc oxide and Enterococcus faecium NCIMB 10415 supplementation on Campylobacter coli levels in weaned piglets". International Journal of Medical Microbiology 302 (2012): 56-56. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000311593300196&KeyUID=WOS:000311593300196.
  42. Buecker, Roland; Azevedo-Vethacke, Marina; Groll, Claudia; Garten, Desiree; Josenhans, Christine; Suerbaum, Sebastian; Schreiber, Soeren. "Helicobacter pylori colonization critically depends on postprandial gastric conditions". Scientific Reports 2 (2012): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000312448500006&KeyUID=WOS:000312448500006.
    10.1038/srep00994
  43. Buecker, Roland; Krug, Susanne M.; Rosenthal, Rita; Guenzel, Dorothee; Fromm, Anja; Zeitz, Martin; Chakraborty, Trinad; et al. "Aerolysin disturbs tight junction integrity and epithelial restitution". Faseb Journal 25 (2011): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000310708400924&KeyUID=WOS:000310708400924.
  44. Buecker, Roland; Krug, Susanne M.; Rosenthal, Rita; Guenzel, Dorothee; Fromm, Anja; Zeitz, Martin; Chakraborty, Trinad; et al. "Aerolysin From Aeromonas hydrophila Perturbs Tight Junction Integrity and Cell Lesion Repair in Intestinal Epithelial HT-29/B6 Cells". Journal of Infectious Diseases 204 8 (2011): 1283-1292. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000294970100018&KeyUID=WOS:000294970100018.
    10.1093/infdis/jir504
  45. Hering, Nina A.; Richter, Jan F.; Krug, Susanne M.; Guenzel, Dorothee; Fromm, Anja; Bohn, Erwin; Rosenthal, Rita; et al. "Modulation of epithelial barrier function by pathogenic Y. enterocolitica or probiotic E. coli Nissle". Faseb Journal 25 (2011): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000310708400467&KeyUID=WOS:000310708400467.
  46. Nielsen, Hans Linde; Nielsen, Henrik; Ejlertsen, Tove; Engberg, Jorgen; Guenzel, Dorothee; Zeitz, Martin; Hering, Nina A.; et al. "Oral and Fecal Campylobacter concisus Strains Perturb Barrier Function by Apoptosis Induction in HT-29/B6 Intestinal Epithelial Cells". Plos One 6 8 (2011): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000295832000068&KeyUID=WOS:000295832000068.
    10.1371/journal.pone.0023858
  47. Hering, Nina A.; Richter, Jan F.; Krug, Susanne M.; Guenzel, Dorothee; Fromm, Anja; Bohn, Erwin; Rosenthal, Rita; et al. "Yersinia enterocolitica induces epithelial barrier dysfunction through regional tight junction changes in colonic HT-29/B6 cell monolayers". Laboratory Investigation 91 2 (2011): 310-324. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000286808700013&KeyUID=WOS:000286808700013.
    10.1038/labinvest.2010.180
  48. Buecker, Roland; Schumann, Michael; Amasheh, Salah; Schulzke, Joerg-Dieter; Yu, ASL. "Claudins in Intestinal Function and Disease". Claudins 65 (2010): 195-227. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000280437500009&KeyUID=WOS:000280437500009.
    10.1016/S1063-5823(10)65009-0
  49. Buecker, Roland; Troeger, Hanno; Kleer, Josef; Fromm, Michael; Schulzke, Joerg-Dieter. "Arcobacter butzleri Induces Barrier Dysfunction in Intestinal HT-29/B6 Cells". Journal of Infectious Diseases 200 5 (2009): 756-764. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000268683900014&KeyUID=WOS:000268683900014.
    10.1086/600868
  50. Buecker, Roland; Troeger, Hanno; Fromm, Michael; Schulzke, Joerg D.. "Arcobacter Butzleri Induces Barrier Dysfunction in HT-29/B6 Epithelial Cells". Gastroenterology 136 5 (2009): A630-A630. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000275277203160&KeyUID=WOS:000275277203160.
  51. Schreiber, Soeren; Garten, Desiree; Nguyen, Thanh Hoa; Konradt, Manuela; Buecker, Roland; Scheid, Peter. "In situ measurement of pH in the secreting canaliculus of the gastric parietal cell and adjacent structures". Cell and Tissue Research 329 2 (2007): 313-320. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000247932400011&KeyUID=WOS:000247932400011.
    10.1007/s00441-007-0427-1
  52. Sudhoff, Holger; Buecker, Roland; Groll, Claudia; Shagdarsuren, Sara; Dazert, Stefan; Schreiber, Soeren. "Tracing of gastric reflux into the middle ear in a Mongolian gerbil model". Otology & Neurotology 28 1 (2007): 124-128. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000243360800021&KeyUID=WOS:000243360800021.
    10.1097/01.mao.0000244358.72626.11
  53. Schreiber, S; Bucker, R; Groll, C; Azevedo-Vethacke, M; Scheid, P; Gatermann, S; Josenhans, C; Suerbaum, S. "Gastric antibacterial efficiency is different for pepsin A and C". Archives of Microbiology 184 5 (2006): 335-340. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000233995400009&KeyUID=WOS:000233995400009.
    10.1007/s00203-005-0053-9
  54. Schreiber, S; Bucker, R; Groll, C; Azevedo-Vethacke, M; Garten, D; Scheid, P; Friedrich, S; et al. "Rapid loss of motility of Helicobacter pylori in the gastric lumen in vivo". Infection and Immunity 73 3 (2005): 1584-1589. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000227373300035&KeyUID=WOS:000227373300035.
    10.1128/IAI.73.3.1584-1589.2005
Activities

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2020/10 - 2025/04 Mechanismen epithelialer Barrierestörung durch Clostridioides difficile Toxine
Supervisor of Martina Schneemann
2020 - 2025 Unravelling the virulence potential of Aliarcobacter butzleri
Co-supervisor of Cristiana Mateus
Universidade da Beira Interior, Portugal
2022 - 2024 The effect of myrrh on the intestinal epithelial barrier function after induction of inflammation with interleukin-13
Supervisor
 Dr. med. (Degree)
Charité Universitätsmedizin Berlin, Germany
2016/04/01 - 2024 Epitheliale Barrierefunktion des Kolons beim Reizdarmsyndrom
Supervisor of Karem Awad
 Dr. med. (Degree)
Charité Universitätsmedizin Berlin Campus Benjamin Franklin, Germany
2021 - 2023 Intestinal epithelial barrier dysfunction by microcystin in Caco-2 cells
Supervisor of Jan-leo Kaak
 Dr. med. (Degree)
Charité Universitätsmedizin Berlin, Germany
2017/10/15 - 2021/04/30 Mechanismen der Barriere-Protektion von Resveratrol und Curcumin bei Campylobacter jejuni-Infektion
Supervisor of Fábia Lobo da Fonseca de Sá
 Dr. rer. nat. (PhD)
Freie Universität Berlin, Germany
2012/03/01 - 2017/04/06 Die protektive Wirkung von Zink auf Escherichia coli a Hämolysin-induzierte Darm-Läsionen
Supervisor
 Dr. rer. nat. (PhD)
Freie Universität Berlin, Germany

Association member

Society Organization name Role
2006 - Current German Society for Hygiene and Microbiology Member of section Microbial Pathogenesis, Member of section Zoonosis.

Committee member

Activity description
Role 		Institution / Organization
2017/01/01 - Current Doctoral commitee of the Charité
Member
 Charité Universitätsmedizin Berlin Campus Benjamin Franklin, Germany

Conference scientific committee

Conference name Conference host
2012 - Current ESCCMID conference, Trusted Reviewer The European Society of Clinical Microbiology and Infectious Diseases
2021/09/01 - 2021/11/10 ESCCMID conference, Trusted Reviewer, Scientific Grant Review The European Society of Clinical Microbiology and Infectious Diseases

Journal scientific committee

Journal title (ISSN) Publisher
2021/08/30 - Current TOXINS Editorial Board Member (2072-6651) MDPI
2024/05/01 - 2025/04/30 Frontiers in Pharmacology (1663-9812) Research Topic: Therapeutic and Protective Approaches to Gastrointestinal Tract Infections
2021/10/31 - 2022/11/01 TOXINS- Special Issue on Bacterial Enterotoxins ( 2072-6651) MDPI
2020/10/01 - 2021/06/14 TOXINS Topic Editor & Guest Editor (ISSN 2072-6651) MDPI
Distinctions

Award

2009 Award of the Japanese Society for Campylobacter Research
Niigata Daigaku, Japan