Rui Manuel Dias Cortesão dos Santos Bernardes (DB19-B18E-690C)

Curriculum Vitae

Rui Manuel Dias Cortesão dos Santos Bernardes

I am a full-time Assistant Professor at the Faculty of Medicine of the University of Coimbra (FMUC) since April 2015, a member of the executive board of CIBIT (Coimbra Institute for Biomedical Imaging and Translational Research) since June 2019, and a member of the scientific council of ICNAS (Institute of Nuclear Sciences Applied to Health, University of Coimbra) since 2011. Before that, I was the director of the Centre for New Technologies for Medicine (CNTM) at the AIBILI (Association for Innovation and Biomedical Research on Light and Image) (1999-2014), member of the board of directors at AIBILI (1999-2014), the coordinator of the research line ”Image Processing, Functional Imaging and Phenotyping of Complex Diseases” at IBILI (Institute for Biomedical Research in Light and Image at FMUC)(2009-2013), and adviser to the board of directors at FCT-The Portuguese Foundation for Science and Technology (2014-2016). I also served as section secretary (2014-2017) and technical adviser (2010-2017) for the IEEE-EMBS Portuguese Chapter, member of the scientific council for the Institute for Interdisciplinary Research, University of Coimbra (IIIUC)(2012-2013) and ICNAS (2008-2009), and consultant for Alcon Research Institute (Texas, USA) (2009-2010). EVER Fellow (2023). Keynote speaker at the XV Mediterranean Conference on Medical and Biological Engineering and Computing (MEDICON) and committee member for ten national and international conferences. Principal investigator (PI) in seven research projects, co-PI in another two, and team member in 21 research projects, all with national or international competitive funding, and one industry-funded research project. Editor of one book, author of five full chapters and six sections of book chapters, over 50 journal papers (Scopus h-index of 19), over 30 international conference proceedings, keynote speaker at one international conference, 13 invited talks, over 100 talks, and over 100 posters (international conferences only). Supervisor of three postdoctoral fellows, two PhD students (ongoing), and co-supervisor of another four PhD students (ongoing). I organized/co-organized several national conferences and meetings, international sessions, special interest symposia, and courses at several international conferences. I have been reviewing for several international journals, national and international conferences, and international funding agencies since 2004.

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Identification

Personal identification

Full name: Rui Manuel Dias Cortesão dos Santos Bernardes

Citation names

Bernardes, R.
Rui C Bernardes

Author identifiers

Ciência ID: DB19-B18E-690C
ORCID iD: 0000-0002-6677-2754
AuthenticusID: R-000-FXF
Google Scholar ID: aMxZyjQAAAAJ&hl
Researcher Id: M-4231-2013
Scopus Author Id: 7004634386

Email addresses

rmbernardes@fmed.uc.pt (Professional)
ruicortesaobernardes@gmail.com (Personal)

Telephones

Telephone

(351) 239480200 (Professional)

Addresses

Faculdade de Medicina, Universidade de Coimbra, Pólo III, Azinhaga Sta Comba, Celas, 3000-548, Coimbra, Coimbra, Portugal (Professional)

Websites

https://www.uc.pt/en/uid/cibit/AboutUs/CIBITpeople (Scholar)

Knowledge fields

Medical and Health Sciences - Other Medical Sciences
Engineering and Technology - Electrotechnical Engineering, Electronics and Informatics

Languages

Language	Speaking	Reading	Writing	Listening
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
French	Elementary (A2)	Elementary (A2)	Elementary (A2)	Elementary (A2)
Portuguese (Mother tongue)

Education

	Degree	Classification
2011 - 2011 Concluded	TIPs Fundamentos (Outros) Faculdade de Medicina, Universidade de Coimbra, Portugal
2008 Concluded	Doutoramento em Ciências da Saúde (Doutoramento) Major in Ciências Biomédicas Universidade de Coimbra, Portugal "Desenvolvimento de Novas Metodologias para o Mapeamento Multimodal da Mácula." (THESIS/DISSERTATION)	Distinção e Louvor
2000/07/25 Concluded	Mestrado em Engenharia Biomédica (Mestrado) Major in Instrumentação Biomédica Universidade de Coimbra, Portugal "A fluorometria confocal por laser do humor vítreo na avaliação do transporte de fluoresceína." (THESIS/DISSERTATION)	Muito Bom
1992 Concluded	Engenharia Electrotécnica (Licenciatura) Major in Informática Universidade de Coimbra, Portugal "Tacto – aquisição e tratamento de sinais provenientes de sensores piezoeléctricos e programação de microcontroladores" (THESIS/DISSERTATION)	Bom

Affiliation

Science

	Category Host institution	Employer
2018/01 - Current	Researcher (Research)	Coimbra Institute for Biomedical Imaging and Translational Research, Portugal
	Instituto das Ciências Nucleares Aplicadas à Saúde, Portugal
2016/01 - Current	Researcher (Research)	Faculdade de Medicina, Universidade de Coimbra, Portugal
	CNC.IBILI, Portugal
2011/12 - Current	Researcher (Research)	Instituto das Ciências Nucleares Aplicadas à Saúde, Portugal

2014/05 - 2016/04	Science and Technology Management	Fundação para a Ciência e a Tecnologia, Portugal

1997/03 - 2015/12	Researcher (Research)	Faculdade de Medicina, Universidade de Coimbra, Portugal
	CNC.IBILI, Portugal
1999/10 - 2014/03	Researcher (Research)	Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal

Teaching in Higher Education

	Category Host institution	Employer
2015/04 - Current	Assistant Professor (University Teacher)	Faculdade de Medicina, Universidade de Coimbra, Portugal

2009/07 - 2015/04	Assistant (University Teacher)	Faculdade de Medicina, Universidade de Coimbra, Portugal

2007/03 - 2009/07	Trainee Assistant (University Teacher)	Faculdade de Medicina, Universidade de Coimbra, Portugal

Positions / Appointments

	Category Host institution	Employer
2019/06 - Current	Executive board member	Coimbra Institute for Biomedical Imaging and Translational Research, Portugal

2011/12/05 - Current	Scientific council member	Instituto das Ciências Nucleares Aplicadas à Saúde, Portugal
	Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal
2014/02 - 2017/12/31	Section Secretary	IEEE - EMBS Portuguese Chapter, Portugal

2010/01 - 2017/12	Technical adviser	IEEE - EMBS Portuguese Chapter, Portugal

2014/05/01 - 2016/04/30	Adviser to the Board of Directors	Fundação para a Ciência e a Tecnologia, Portugal
	Fundação para a Ciência e a Tecnologia, Portugal
2013/02 - 2014/03	Member of the scientific council	Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal
	Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal
1999/10 - 2014/03	Director of the Center of New Technologies for Medicine	Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal

1999/10 - 2014/03	Member of the board of directors	Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal
	Associação para a Investigação Biomédica e Inovação em Luz e Imagem, Portugal
2012/01 - 2013/12	Scientific council member	Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
	Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2009/06 - 2013/12	Coordinator: Image Processing, Functional Imaging and Phenotyping of Complex Diseases	Faculdade de Medicina, Universidade de Coimbra, Portugal
	Faculdade de Medicina, Universidade de Coimbra, Portugal
2008 - 2009	Scientific council member	Instituto das Ciências Nucleares Aplicadas à Saúde, Portugal
	Instituto das Ciências Nucleares Aplicadas à Saúde, Portugal
2003 - 2007	Director of the Retinal Imaging Unit, Centre of Ophthalmology	Faculdade de Medicina, Universidade de Coimbra, Portugal
	Faculdade de Medicina, Universidade de Coimbra, Portugal
1997 - 1999	Fellow	Fundação para a Ciência e a Tecnologia, Portugal
	Faculdade de Medicina, Universidade de Coimbra, Portugal
1995 - 1997	Consultant	Parêntesis - Engenharia de Software, Lda, Portugal

1992 - 1995	Co-founder & Director	Parêntesis - Engenharia de Software, Lda, Portugal

Projects

Contract

	Designation	Funders
2021/01/01 - 2025/12/31	Laboratório Associado de Sistemas Inteligentes 10.54499/LA/P/0104/2020 Universidade Nova de Lisboa Centro de Tecnologias e Sistemas, Portugal Universidade de Aveiro Centro de Tecnologia Mecânica e Automação, Portugal Instituto Politécnico do Porto Centro de Investigação em Sistemas Computacionais Embebidos e de Tempo-Real, Portugal Universidade do Minho, Portugal Universidade do Porto Faculdade de Ciências, Portugal Universidade do Porto Centro de Matemática, Portugal Instituto Politécnico do Cávado e do Ave, Portugal Universidade do Porto Laboratório de Inteligência Artificial e Ciência de Computadores, Portugal Universidade do Minho Instituto de Polímeros e Compósitos, Portugal Universidade de Aveiro Instituto de Engenharia Eletrónica e Informática de Aveiro, Portugal Universidade do Minho Centro ALGORITMI, Portugal Universidade Nova de Lisboa Unidade de Investigação e Desenvolvimento em Engenharia Mecânica e Industrial, Portugal Universidade de Coimbra, Portugal Instituto Politécnico do Porto Instituto Superior de Engenharia do Porto, Portugal Universidade de Coimbra Centro de Informatica e Sistemas, Portugal Instituto Politécnico do Porto Grupo de Investigação em Engenharia e Computação Inteligente para a Inovação e o Desenvolvimento, Portugal Universidade de Aveiro, Portugal Universidade do Porto Faculdade de Engenharia, Portugal Universidade NOVA de Lisboa, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2021/01/01 - 2025/12/31	Intelligent Systems Associate Laboratory LA/P/0104/2020 Universidade Nova de Lisboa Centro de Tecnologias e Sistemas, Portugal Universidade de Aveiro Centro de Tecnologia Mecânica e Automação, Portugal Instituto Politécnico do Porto Centro de Investigação em Sistemas Computacionais Embebidos e de Tempo-Real, Portugal Universidade do Minho, Portugal Universidade do Porto Faculdade de Ciências, Portugal Universidade do Porto Centro de Matemática, Portugal Instituto Politécnico do Cávado e do Ave, Portugal Universidade do Porto Laboratório de Inteligência Artificial e Ciência de Computadores, Portugal Universidade do Minho Instituto de Polímeros e Compósitos, Portugal Universidade de Aveiro Instituto de Engenharia Eletrónica e Informática de Aveiro, Portugal Universidade do Minho Centro ALGORITMI, Portugal Universidade Nova de Lisboa Unidade de Investigação e Desenvolvimento em Engenharia Mecânica e Industrial, Portugal Universidade de Coimbra, Portugal Instituto Politécnico do Porto Instituto Superior de Engenharia do Porto, Portugal Universidade de Coimbra Centro de Informatica e Sistemas, Portugal Instituto Politécnico do Porto Grupo de Investigação em Engenharia e Computação Inteligente para a Inovação e o Desenvolvimento, Portugal Universidade de Aveiro, Portugal Universidade do Porto Faculdade de Engenharia, Portugal Universidade NOVA de Lisboa, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2023/03 - 2024/08	Searching for a neurovascular coupling reflex pathway 2022.07585.PTDC Principal investigator Universidade de Coimbra Centro de Imagem Biomédica e Investigação Translacional, Portugal	Fundação para a Ciência e Tecnologia Ongoing
2018/12 - 2021/12	Efficient Simulation and Computation for Health, Sea and Industry. PTDC/MAT-APL/28118/2017 Researcher Coimbra Institute for Biomedical Imaging and Translational Research, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2018/10/01 - 2021/09/30	Optical Coherence Elastography for imaging retina mechanical properties. PTDC/EMD-EMD/32162/2017 Researcher Coimbra Institute for Biomedical Imaging and Translational Research, Portugal Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2018/08 - 2021/07	Non-invasive optical coherence tomography towards the imaging of the neurodegenerative disease: from the animal retina to the human brain. PTDC/EMD-EMD/28039/2017 Principal investigator Coimbra Institute for Biomedical Imaging and Translational Research, Portugal Universidade Aberta, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2018/06/22 - 2021/06/21	Novos biomarcadores de imagem multimodal de conectividade neuronal na Esclerose Múltipla PTDC/MEC-NEU/31973/2017 Universidade de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia Ongoing
2018/07 - 2021/06	Novel multimodal imaging biomarkers of neuronal connectivity in Multiple Sclerosis. PTDC/MEC-NEU/1973/2017 Researcher Coimbra Institute for Biomedical Imaging and Translational Research, Portugal Instituto das Ciências Nucleares Aplicadas à Saúde, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2018/07 - 2021/06	Brain Elasticity in Multiple Sclerosis and implications in mechanomodulation of oligodendrocytes: a cellular and clinical approach. PTDC/MED-NEU/29516/2017 Researcher Coimbra Institute for Biomedical Imaging and Translational Research, Portugal BIOCANT - Associação de Transferência de Tecnologia, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2017/01 - 2020/10/31	From computational modelling and clinical research to the development of neuroimaging big data platforms for discovery of novel biomarker. CENTRO-01-0145-FEDER-000016 Researcher Instituto das Ciências Nucleares Aplicadas à Saúde, Portugal	Comissão de Coordenação e Desenvolvimento Regional do Centro Concluded
2019/01/01 - 2019/12/31	CNC. IBILI UID/NEU/04539/2019 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal Universidade de Coimbra, Portugal Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde, Portugal Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2016/01 - 2018/12	The changing brain in Alzheimer's disease: is the retina a reliable mirror of diseases onset and progression? MB-1049-2015 Researcher Faculdade de Medicina, Universidade de Coimbra, Portugal	Santa Casa da Misericórdia de Lisboa Concluded
2013/05 - 2015/09	Unveiling preclinical idiopathic macular hole formation: structural changes by high-definition optical coherence tomography and machine learning. PTDC/BBB-BMD/2739/2012 Principal investigator Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal Faculdade de Medicina, Universidade de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2013/06/01 - 2015/06/30	From molecules to man: novel diagnostic imaging tools in neurological and psychiatric disorders. CENTRO-07-ST24-FEDER-00205 Researcher Instituto das Ciências Nucleares Aplicadas à Saúde, Portugal	Comissão de Coordenação e Desenvolvimento Regional do Centro Concluded
2012/04 - 2015/03	Optical Modelling of the Human Retina in Health and Disease: from structure to function. PTDC/SAU-ENB/119132/2010 Principal investigator Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal Faculdade de Medicina, Universidade de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2011/02 - 2014/07	3D retinal vascular network from Optical Coherence Tomography data. PTDC/SAU-ENB/111139/2009 Researcher Faculdade de Medicina, Universidade de Coimbra, Portugal Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010/04 - 2014/03	Comprehensive analysis of rod-cone photoreceptor degeneration associated with rhodopsin mutations E-Rare2/SAU/0001/2008 Researcher Faculdade de Medicina, Universidade de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010/03/22 - 2013/06	Correlation phenotype/genotype in diabetic retinopathy. PTDC/SAU-OSM/103226/2008 Researcher Faculdade de Medicina, Universidade de Coimbra, Portugal Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal BIOCANT - Associação de Transferência de Tecnologia, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010/03/15 - 2013/03/14	Evaluation of blood-retinal barrier functional alterations by optical coherence tomography. PTDC/SAU-BEB/103151/2008 Principal investigator Faculdade de Medicina, Universidade de Coimbra, Portugal Universidade de Coimbra, Portugal Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal CNC.IBILI, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2008/11 - 2012/03	A new route for endothelial dysfunction on diabetes: From phenotypes to molecules. PTDC/SAU-OSM/67498/2006 Researcher Faculdade de Medicina, Universidade de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluded
2008/04 - 2012/03	Development and clinical applications of a system with adaptive optics for ocular tomography and high-resolution retinal imaging. PTDC/SAU-BEB/72220/2006 Researcher Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2007/09 - 2011/11	Validation of a predictive model to estimate the risk of conversion to clinically significant macular edema and/or vision loss in mild nonproliferative diabetic retinopathy in diabetes type 2. PTDC/SAU-OSM/72635/2006 Researcher Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2005/03 - 2009/11	Pfizer Global - MESF Fluorescein Quantification Pfizer Global MESF Principal investigator Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal Pfizer Inc, United States	Pfizer Inc Concluded
2005/12 - 2009/06	Characterization of early markers of choroidal neovascularization in fellow eyes of patients with AMD and CNV in one eye. Two-year follow-up. Pfizer Clinical Trial CNV Mark Researcher Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Pfizer Global Research and Development Concluded
2005 - 2009	EVI-GENORET - Functional Genomics of the Retina in Health and Disease LSHG-CT-2005-512036 Researcher Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal	European Commission Sixth Framework Programme Concluded
2005/06/01 - 2008/05/31	Structure-function imaging for quantitative phenotyping of retinal degenerations POSC/EEA-SRI/60716/2004 Researcher	Fundação para a Ciência e a Tecnologia Concluded
2005/10/02 - 2007/12/31	Biology of human photoreceptors and ganglion cells in health and disease: Phenotyping retinal degenerations. POCI/SAU-OBS/57070/2004 Researcher Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2004 - 2007	Multi-Modality Medical Image Registration for Eye Diagnosis. POSI/SRI/45151/2002 Researcher Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2003/02 - 2006/12	Characterization of the mechanisms of resolution of diabetic macular edema after photocoagulation treatment with laser. POCTI/CBO/43061/2001 Researcher Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal CNC.IBILI, Portugal Universidade de Coimbra, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2000/11 - 2006/05	Prospective study of the initial changes occurring in the retinal microcirculation in diabetes by multimodal imaging of the eye fundus. POCTI/CBO/35866/1999 Researcher Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2002 - 2006	EVIGeM- European Virtual Institute for Geometry Measurements G7RT-CT-2002-05086 Researcher Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal	European Commission Concluded
2000 - 2003	GLAUCAD - Glaucoma Prevention by Computer Aided Diagnostics QLG1-2000-00651 Researcher Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal	European Commission Concluded
2002/01 - 2002/12	Desenvolvimento de Novas Tecnologias e Instrumentação para Exame Clínico da Mácula POE Nº 4 Principal investigator Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal	Comissão de Coordenação e Desenvolvimento Regional do Centro Concluded
1996 - 1999	Fluorometria cinética e topográfica do vítreo usando um novo sistema óptico confocal de alta resolução em normais e diabéticos PRAXIS 2/2.1/SAU/1301/1995 Scientific Initiation Fellow CNC.IBILI, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Outputs

Publications

Book chapter	Serranho, Pedro; Morgado, António Miguel; Bernardes, Rui. "Optical coherence tomography: a concept review". Portugal: Springer Berlin Heidelberg, Pedro Serranho; Sílvia Barbeiro; Rafael Henriques; Ana Batista; Mário Santos; Carlos Correia; José Domingues; et al. "On the Numerical Solution of the Inverse Elastography Problem for Time-harmonic Excitation". 2022. 10.5220/0011125900003209 Ana Batista; Carlos Correia; Sílvia Barbeiro; João Cardoso; José Domingues; Rafael Henriques; Custódio Loureiro; et al. "Swept-source Phase-Stabilized Optical Coherence Tomography Setup for Elastography". 2022. 10.5220/0011126500003209 Rui Bernardes; Hugo Ferreira; Pedro Guimarães; Pedro Serranho. "Shedding Light on Early Central Nervous System Changes for Alzheimer’s Disease through the Retina: An Animal Study". 2022. 10.5220/0011125600003209 Bernardes, Rui; Jorge, Lília; Nunes, Ana; Castelo-Branco, Miguel. "Machine Learning Approaches in OCT: Application to Neurodegenerative Disorders". In OCT and Imaging in Central Nervous System Diseases, 507-521. Springer International Publishing, 2020. 10.1007/978-3-030-26269-3_23 Nunes, Ana; Serranho, Pedro; Quental, Hugo; Castelo-Branco, Miguel; Bernardes, Rui. "The Effect of Menopause on the Sexual Dimorphism in the Human Retina – Texture Analysis of Optical Coherence Tomography Data". In Lecture Notes in Computer Science, 344-357. Springer International Publishing, 2020. Published • 10.1007/978-3-030-50516-5_30 Nunes, Ana; Serranho, Pedro; Quental, Hugo; Ambrósio, António Francisco; Castelo-Branco, Miguel; Bernardes, Rui. "Sexual Dimorphism of the Adult Human Retina Assessed by Optical Coherence Tomography". In XV Mediterranean Conference on Medical and Biological Engineering and Computing – MEDICON 2019, 1830-1834. Springer International Publishing, 2019. Published • 10.1007/978-3-030-31635-8_222 Ferreira, Hugo; Martins, João; Nunes, Ana; Moreira, Paula I.; Castelo-Branco, Miguel; Ambrósio, António Francisco; Serranho, Pedro; Bernardes, Rui. Corresponding author: Bernardes, Rui. "Characterization of the Retinal Changes of the 3xTg-AD Mouse Model of Alzheimer’s Disease". In XV Mediterranean Conference on Medical and Biological Engineering and Computing – MEDICON 2019, 1816-1821. Springer International Publishing, 2019. Published • 10.1007/978-3-030-31635-8_220 Bernardes, Rui; Silva, Gilberto; Chiquita, Samuel; Serranho, Pedro; Ambrósio, António Francisco. "Retinal Biomarkers of Alzheimer’s Disease: Insights from Transgenic Mouse Models". In Image Analysis and Recognition, 541-550. Cham: Springer International Publishing, 2017. Published • 10.1007/978-3-319-59876-5_60 Bernardes, Rui; Silva, Gilberto; Chiquita, Samuel; Serranho, Pedro; Ambrósio, António Francisco. "Retinal Biomarkers of Alzheimer’s Disease: Insights from Transgenic Mouse Models". In Lecture Notes in Computer Science, 541-550. Springer International Publishing, 2017. 10.1007/978-3-319-59876-5_60 Silva, SF; Domingues, JP; Agnelo, J.; Morgado, AM; Bernardes, R.. "Development of an Optical Coherence Tomograph for Small Animal Retinal Imaging". In XIII Mediterranean Conference on Medical and Biological Engineering and Computing 2013, 419-422. Cham, Switzerland: Springer International Publishing, 2014. Published • 10.1007/978-3-319-00846-2_104 Ana Sílvia C. Silva; João Fizucira; Sílvia Simão; Nuno Gomes; Carlos Neves; Angelina Meireles; Natália Ferreira; Rui Bernardes. "Unveiling Preclinical Idiopathic Macular Hole Formation Using Support Vector Machines". 2014. 10.1109/bhi.2014.6864432 Rodrigues, P.; Guimarães, P.; Araújo, A.; Barbeiro, S.; Bernardes, R.; Serranho, P.. "Explicit and Semi-implicit Complex-Diffusion Schemes for Optical Coherence Tomography Despeckling". In Image Analysis and Recognition, 282-289. Berlin, Heidelberg, Germany: Springer Berlin Heidelberg, 2013. Published • 10.1007/978-3-642-39094-4_32 Cunha-Vaz, J.; Bernardes, R.; Lobo, C.. "Clinical Phenotypes of Diabetic Retinopathy". In Visual Dysfunction in Diabetes, 53-68. New York, NY, Portugal: Springer New York, 2012. Published • 10.1007/978-1-60761-150-9_5 Maduro, C.; Serranho, P.; Santos, T.; Rodrigues, P.; Cunha-Vaz, J.; Bernardes, R.. "OCT Noise Despeckling Using 3D Nonlinear Complex Diffusion Filter". In Technologies for Medical Sciences, 141-157. Dordrecht, Portugal: Springer Netherlands, 2012. Published • 10.1007/978-94-007-4068-6_7 Cunha-Vaz, J.; Bernardes, R.; Santos, T.; Oliveira, C.; Lobo, C.; Pires, I.; Ribeiro, L.. "Computer-Aided Detection of Diabetic Retinopathy Progression". In Digital Teleretinal Screening: Teleophthalmology in Practice, 59-66. Berlin, Heidelberg, Portugal: Springer Berlin Heidelberg, 2012. Published • 10.1007/978-3-642-25810-7_6 Guimarães, P.; Rodrigues, P.; Serranho, P.; Bernardes, R.. "3D Retinal Vascular Network from Optical Coherence Tomography Data". In Image Analysis and Recognition, 339-346. Berlin, Heidelberg, Portugal: Springer Berlin Heidelberg, 2012. Published • 10.1007/978-3-642-31298-4_40 Bernardes, R.; Cunha-Vaz, J.. "Evaluation of the Blood-Retinal Barrier with Optical Coherence Tomography". In Optical Coherence Tomography: A Clinical and Technical Update, 157-174. Berlin, Heidelberg, Portugal: Springer Berlin Heidelberg, 2012. Published • 10.1007/978-3-642-27410-7_8 Rui Bernardes. "Diabetic Macular Edema". edited by Bernardes, Rui; Cunha-Vaz, Jos{\'e, 1-21. Springer Berlin Heidelberg, 2012. 10.1007/978-3-642-27410-7_1 Santos, T.; Bernardes, R.; Santos, A.; Cunha-Vaz, J.. "Noninvasive Assessment of Blood-Retinal Barrier Function by High-Definition Optical Coherence Tomography.". In Technology and Medical Sciences, 215-219. The Netherlands, Portugal: CRC Press, 2011. Published • 10.1201/b11330-40 Figueira, F.; Bernardes, R.; Cunha-Vaz, J.. "Clinical Diagnostic Methodologies: Measurements of Retinal Thickness". In Diabetic Retinopathy, 61-69. Singapore, Singapore: World Scientific Publishing, 2010. Published Bernardes, R.; Lobo, C.; Cunha-Vaz, J.. "Clinical Diagnostic Methodologies: Multimodal Macula Mapping". In Diabetic Retinopathy, 95-100. Singapore, Singapore: World Scientific Publishing Co. Pte. Ltd., 2010. Published Bernardes, R.; Lobo, C.; Cunha-Vaz, J.. "3.6. Multimodal macula mapping". 95-100. 2010. Figueira, J.; Bernardes, R.; Cunha-Vaz, J.. "Medición del espesor retiniano". In Retinopatía Diabética, 73-77. Barcelona, Espanha, Spain: Sociedad Española de Oftalmología, 2006. Published Bernardes, R.; Lobo, C.; Cunha-Vaz, J.. "Cartografía multimodal de la Mácula". In Retinopatía Diabética, 1-320. Espanha, Spain: Sociedad Española de Oftalmología, 2006. Published Cunha-Vaz, J.; Bernardes, R.; Castelo-Branco, M.. "Fluorometria, Electrofisiologia, Mapa Macular Digital e Psicofísica". In Retinopatía Diabética. Tratado Médico Quirurgico, 89-104. Espanha, Spain: Sociedad Espanola de Oftalmologia, 2006. Published Rui Bernardes. "Novel imaging techniques for diabetic macular edema". edited by Wolfensberger, Thomas J., 137-143. Springer Netherlands, 1999. 10.1007/978-94-011-4152-9_16
Conference abstract	Rui C Bernardes; Ana Nunes; Guimarães, Pedro; Pedro Serranho; Castelo-Branco, Miguel. "Central nervous system interocular sex differences spotted at the retina by texture analysis". Paper presented in ARVO Annual Meeting, New Orleans, 2023. Accepted Ana Batista; Pedro Serranho; Mário Santos; Carlos Correia; José Domingues; Custódio Loureiro; João Cardoso; et al. "Novel method for higher-resolution displacement computation in phase-resolved optical coherence elastography". Paper presented in Focus on Microscopy (FOM) 2022, Porto, 2022. Published Bernardes, R.. "Retinal biomarkers for Alzheimer's and Parkinson's diseases". Paper presented in EVER, Nice, 2018. Published • 10.1111/aos.13972_38 Bernardes, R.. "Inner retinal layers of the retina predict visual cortical thickness and structural connectivity in early Alzheimer's disease". Paper presented in EVER, Nice, 2018. Published • 10.1111/aos.13972_61 Bernardes, R.. "Retina, a mirror of the brain: an association between macular and cerebral structural integrity over age". Paper presented in EVER, Nice, 2018. Published • 10.1111/aos.13972_209 Bernardes, R.. "Retina changes in Alzheimer's disease: potential biomarker for dementia". Paper presented in European Academy of Neurology (EAN), Lisboa, 2018. Published Duque, Cristina; Januário, Cristina; Lemos, João; Fonseca, P.; António L. Correia; Ribeiro, L.; Bernardes, R.; Freire, António. "Optical coherence tomography in LRRK2-associated Parkinson Disease". Paper presented in American Academy of Neurology, Washington, 2015. Published QUENDERA, B; AMORIM, A; CORDEIRO, M; FERREIRA, C; MARQUES, J; BERNARDES, R; REIS, A; RIBEIRO, L; CASTELO-BRANCO, M. "Visual impairment in diabetic patients with and without established blood-retinal barrier leakage and relation with the status of the blood-brain barrier". Paper presented in EVER, Nice, 2014. Published • 10.1111/j.1755-3768.2014.2445.x António L. Correia; Luis Pinto; Adérito Araújo; Miguel Morgado; Sílvia Barbeiro; Francisco Caramelo; Paulo Menezes; Pedro Serranho; Rui Bernardes. "Monte Carlo simulation of diabetic macular edema changes on optical coherence tomography". Paper presented in Annual Meeting of the Association for Research in Vision and Ophthalmology (ARV=), Orlando, Florida, EUA, 2014. Published Rui Bernardes; António L. Correia; Otília d'Almeida; S. Batista; Lívia Sousa; Miguel Castelo-Branco. "Optical properties of the human retina as a window into systemic and brain diseases". Paper presented in Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO), Orlando, Florida, EUA, 2014. Published Ana Sílvia C. Silva; João Figueira; Sílvia Simão; Nuno Gomes; Carlos Neves; Angelina Meireles; Natália Ferreira; Rui Bernardes. "Preclinical Identification of eyes at Risk of Developing Idiopathic Macular Hole - An Update". Paper presented in The Association for Research in Vision and Ophthalmology Annual Meeting, Orlando, Florida, USA, 2014. Published Ana Sílvia C. Silva; Figueira, J.; Lobo, C.; Simão, S.; Angelina Meireles; Nuno Gomes; Bernardes, R.. "Automatic identification of eyes at risk of developing idiopathic macular hole". Paper presented in EVER, Nice, 2014. Published • 10.1111/j.1755-3768.2014.3663.x António L. Correia; Adérito Araújo; Barbeiro, Sílvia; Caramelo, F.; Pedro Serranho; Morgado, AM; Bernardes, R.. "Simulation of DME changes on OCT". Paper presented in EVER 2014, Nice, 2014. Published • 10.1111/j.1755-3768.2014.2443.x Bernardes, R.. "Different genetic polymorphisms are associated with different phenotypes on non-proliferative diabetic retinopathy". Paper presented in The Association for Research in Vision and Ophthalmology (ARVO), Orlando, 2014. Published António L. Correia; Luis Pinto; Adérito Araújo; Sílvia Barbeiro; Pedro Serranho; Miguel Morgado; Francisco Caramelo; Paulo Menezes; Rui Bernardes. "Simulation of DME changes on OCT through Monte Carlo". Paper presented in V Annual Meeting of IBILI, Coimbra, Portugal, 2013. Published Bernardes, R.; Guimarães, P.; Rodrigues, P.; Figueira, J.; Serranho, P.. "Discrimination Between Perfused and Occluded Vessels from OCT Scans". Paper presented in The Association for Research in Vision and Ophthalmology (ARVO), Seattle, Washington, USA, 2013. Published Guimarães, P.; Rodrigues, P.; Lobo, C.; Bernardes, R.; Serranho, P.. "Fully-Automated Multimodal Co-Registration of Optical Coherence Tomography to Colour Fundus Photography and Fluorescein Angiography". Paper presented in The Association for Research in Vision and Ophthalmology (ARVO), Seattle, 2013. Published Rodrigues, P.; Guimarães, P.; Bernardes, R.; Serranho, P.. "Improved 3-Dimensional Retinal Vascular Tree Segmentation and Reconstruction from High-Definition Optical Coherence Tomography". Paper presented in The Association for Research in Vision and Ophthalmology (ARVO), Seattle, Washington, USA, 2013. Published Ana Sílvia C. Silva; João Figueira; Torcato Santos; Sílvia Simão; Rui Bernardes. "Unveiling Preclinical Idiopathic Macular Hole Formation: Structural Changes by High-Definition OCT and Machine Learning". Paper presented in V Annual Meeting of IBILI, Coimbra, Portugal, 2013. Published João Figueira; Ana Sílvia C. Silva; Angelina Meireles; Nuno Gomes; Natália Ferreira; Carlos Neves; Rui Bernardes. "Identificação de Olhos em Risco de Desenvolvimento de Buracos Maculares Idiopáticos". Paper presented in 56º Congresso da Sociedade Portuguesa de Oftalmologia, Vilamoura, Portugal, 2013. Published Farinha, C,; Figueira, J.; Santos, A.; Melo, P.; Guimarães, P.; Rodrigues, P.; Serranho, P.; Bernardes, R.. "Avaliação do estado de perfusão dos vasos retinianos com OCT.". Paper presented in 56º Congresso Português de Oftalmologia, Vilamoura, 2013. Published Bernardes, R.; Guimarães, P.; Rodrigues, P.; Figueira, J.; Serranho, P.. "Non-invasive discrimination between perfused and occluded vessels by optical coherence tomography.". Paper presented in EVER, Nice, 2013. Published Guimarães, P.; Rodrigues, P.; Lobo, C.; Serranho, P.; Bernardes, R.. "Fast fully-automated multimodal image co-registration optical coherence tomography, colour fundus photography, red-free, fluorescein angiography.". Paper presented in EVER 2013, Nice, 2013. Published Rodrigues, P.; Guimarães, P.; Serranho, P.; Bernardes, R.. "Enhanced 3D retinal vascular network reconstruction from high-definition SD-OCT.". Paper presented in EVER, Nice, 2013. Published GUIMARAES, P; RODRIGUES, P; LOBO, C; SERRANHO, P; BERNARDES, R. "Fast fully-automated multimodal image co-registration (optical coherence tomography, colour fundus photography, red-free, fluorescein angiography)". Paper presented in EVER, Nice, 2013. Published • 10.1111/j.1755-3768.2013.4462.x Bernardes, R.. "Patterns of Progression in Diabetic Retinopathy. Correlation between phenotypes and genotypes". Paper presented in The Association for Research in Vision and Ophthalmology (ARVO), Seattle, 2013. Published RODRIGUES, P; GUIMARAES, P; BERNARDES, R; SERRANHO, P. "Vascular network of the human macula from OCT". Paper presented in European Association for Vision and Eye Research, Nice, 2012. Published • 10.1111/j.1755-3768.2012.2713.x BERNARDES, R; SANTOS, T. "Optical coherence tomography: signal signature on neuronal ageing and blood-retinal barrier status". Paper presented in European Association for Vision and Eye Research, Nice, 2012. Published • 10.1111/j.1755-3768.2012.2611.x GUIMARAES, P; RODRIGUES, P; BERNARDES, R; SERRANHO, P. "3D blood vessels segmentation from optical coherence tomography". Paper presented in European Association for Vision and Eye Research, Nice, 2012. Published • 10.1111/j.1755-3768.2012.2712.x Rodrigues, P.; Santos, T.; Pereira, H.; Figueira, J.; Bernardes, R.. "Identification of eyes at risk of developing idiopathic macular holes by support vector machines". Paper presented in 2012 IEEE 2nd Portuguese Meeting in Bioengineering (ENBENG), Coimbra, 2012. Published • 10.1109/ENBENG.2012.6331372 Guimarães, P.; Serranho, P.; Castelo-Branco, M.; Bernardes, R.. "Segmentation Processes and Pattern Recognition in Retina and Brain Imaging". Paper presented in 2nd Portuguese BioEngineering Meeting IEEE-EMBS, Coimbra, 2012. Published • 10.1109/ENBENG.2012.6331395 Rodrigues, P.; Guimarães, P.; Serranho, P.; Bernardes, R.. "3D Retinal Vascular Network from OCT Data". Paper presented in ARVO 2012 Annual Meeting, Fort Lauderdale, Florida, USA, 2012. Published Guimarães, P.; Rodrigues, P.; Bernardes, R.; Serranho, P.. "Vascular Network of the Human Macula from High-Definition OCT". Paper presented in ARVO 2012 Annual Meeting, Fort Lauderdale, Florida, USA, 2012. Published Guimarães, P.; Rodrigues, P.; Serranho, P.; Lobo, C.; Bernardes, R.. "Multi-modal co-registration of fundus images". Paper presented in 4th Annual Meeting of IBILI, Coimbra, 2012. Published Rodrigues, P.; Bernardes, R.. "3D Adaptive Nonlinear Complex-Diffusion Filtering on GPU". Paper presented in 4th Annual Meeting of IBILI, Coimbra, 2012. Published BERNARDES, R; SERRANHO, P; RODRIGUES, P; GONÃ§ALVES, V; CUNHA-VAZ, J. "Blood-retinal barrier function status from OCT data". Paper presented in European Association for Vision and Eye Research, Creta, 2011. Published • 10.1111/j.1755-3768.2011.4115.x Bernardes, R.. "Validation of a predictive model for diabetic retinopathy progression in type-2 diabetic patients with mild NPDR". Paper presented in 47th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Lisboa, 2011. Published Bernardes, R.; Serranho, P.; Rodrigues, P.; Gonçalves, V.; Cunha-Vaz, J.. "Blood-retinal barrier function status from OCT data". Paper presented in EVER 2011, Crete, 2011. Published Nunes, S.; Santos, T.; Pires, I.; Lobo, C.; Bernardes, R.; Cunha-Vaz, J.. "Cluster Analysis Identification Of Early Diabetic Retinopathy Phenotypes". Paper presented in ARVO, Fort Lauderdale, 2011. Published Santos, AR; Cachulo, ML; Fonseca, P.; Nunes, S.; Bernardes, R.; Cunha-Vaz, J.; Silva, R.. "Risk Factors for the Development of Choroidal Neovascularization in the Fellow Eye of Patients with Age Related Macular Degeneration - A Three Year Follow-up Study.". Paper presented in ARVO, Fort Lauderdale, 2011. Published Serranho, P.; Rodrigues, P.; Bernardes, R.. "Optical Coherence Tomography Data Analysis by Support Vector Machines". Paper presented in 11Th Annual Metting of the European Network for Business and Industrial Statistics (ENBIS), Coimbra, 2011. Published Rodrigues, P.; Guimarães, P.; Bernardes, R.; Serranho, P.. "Retinal Vascular Network from 2D OCT Fundus Images". Paper presented in IBILI Meeting, Coimbra, 2011. Published BERNARDES, R; MADURO, C; SERRANHO, P; LOBO, C; CUNHA-VAZ, J. "Optical coherence tomography speckle denoising". Paper presented in European Association for Vision and Eye Research, Creta, 2010. Published • 10.1111/j.1755-3768.2010.4314.x BERNARDES, R; SANTOS, T; CUNHA-VAZ, J. "High-definition Fourier domain OCT: non-invasive assessment of BRB changes". Paper presented in European Association for Vision and Eye Research, Portoroz, 2009. Published • 10.1111/j.1755-3768.2009.2114.x BERNARDES, R; NUNES, S; PEREIRA, I; LOBO, C; CUNHA-VAZ, J. "Semi-automated assessment of microaneurysm formation rate from color fundus photographs in patients with mild NPDR". Paper presented in European Association for Vision and Eye Research, Portoroz, 2009. Published • 10.1111/j.1755-3768.2009.4211.x NUNES, S; BERNARDES, R; LOBO, C; CUNHA-VAZ, J. "Validation of a predictive model for diabetic retinopathy progression in type-2 diabetic patients with mild nonproliferative diabetic retinopathy.". Paper presented in European Association for Vision and Eye Research, Portoroz, 2009. Published • 10.1111/j.1755-3768.2009.4212.x PEREIRA, I; NUNES, S; RIBEIRO, ML; BERNARDES, R; CUNHA-VAZ, J. "Risk markers for progression of mild nonproliferative retinopathy to clinically significant macular edema in type 2 diabetic patients". Paper presented in European Association for Vision and Eye Research, Portoroz, 2008. Published • 10.1111/j.1755-3768.2008.4414.x BERNARDES, R; CUNHA-VAZ, J. "Retinal thickness vs. retinal sensitivity at the central human macula". Paper presented in European Association for Vision and Eye Research, Portoroz, 2008. Published • 10.1111/j.1755-3768.2008.457.x BERNARDES, R; CUNHA-VAZ, J. "New developments in OCT evaluations". Paper presented in European Association for Vision and Eye Research, Portoroz, 2008. Published • 10.1111/j.1755-3768.2008.4112.x SANTOS, T; BERNARDES, R; BAPTISTA, P; SCHWARTZ, A; CARTER, W; CUNHA-VAZ, J. "Quantitative fluorescein angiograms". Paper presented in European Association for Vision and Eye Research, Slovenia, 2007. Published • 10.1111/j.1600-0420.2007.01063_3422.x VAN DIJK, HW; KOK, PHB; ABRAMOFF, MD; SCHLINGEMANN, RO; BERNARDES, R; VERBRAAK, FD. "The sensitivity of OCT in the diagnosis of clinically significant macular edema". Paper presented in European Association for Vision and Eye Research, Portoroz, 2007. Published • 10.1111/j.1600-0420.2007.01062_3258.x BERNARDES, R. "Instrumentation adaptation for quantitative fluorescein angiograms". Paper presented in European Association for Vision and Eye Research, Portoroz, 2007. Published • 10.1111/j.1600-0420.2007.01063_2995.x Bernardes, R.; Baptista, P.; Ferreira, JF; Dias, J.; Cunha-Vaz, J.. "Registration of functional and morphological imaging modalities". Paper presented in 15th Meeting of the EASD Eye Complications Study Group, Coimbra, 2005. Published Torrent-Solans, T.; Duarte, L.; Monteiro, R.; Almeida, E.; Bernardes, R.; Cunha-Vaz, J.. "Red dots counting on digitalized fundus images of mild nonproliferative retinopathy in diabetes type 2". Paper presented in ARVO 2004 Annual Meeting, fort Lauderdale, FL, 2005. Published Bernardes, RC; Nunes, S.; Varandas, J.; Lobo, C.; Cunha-Vaz, J.. "Detailed retinal thickness mapping using the Stratus OCT". Paper presented in ARVO 2004 Annual Meeting, Fort Lauderdale, FL, 2005. Published Duarte, L.G.; Bernardes, R.C.; Soares, M.A.; Lobo, C.L.; Abreu, J.F.; Cunha-Vaz, J.G.. "Retinopathy Phenotypes in Diabetes type 2. Patterns of retinopathy progression in a two year follow-up.". Paper presented in ARVO Annual Meeting 2004, Ft. Lauderdale, Florida, 2004. Published Monteiro, R.F.; Bernardes, R.C.; Almeida, E.S.; Lobo, C.L.; Cunha-Vaz, J.G.. "Reability of the RTA for detecting changes in retinal thickness in preclinical retinopathy in subjects with type 2 diabetes". Paper presented in ARVO Annual Meeting, Fort Lauderdale, Florida, 2003. Published Duarte, L.G.; Lobo, C.L.; Bernardes, R.C.; Soares, M.A.; Figueira, J.P.; Abreu, J.F.; Cunha-Vaz, J.G.. "Macular maps of fluorescein leakage during a 3-year follow-up in patients with type 2 diabetes Mellitus and mild non-proliferative retinopathy". Paper presented in ARVO Meeting, Fort Lauderdale, Florida, 2003. Published Bernardes, R.C.; Monteiro, R.F.; Lobo, C.; Cunha-Vaz, J.. "OCT increased resolution retinal thickness mapping". Paper presented in ARVO Annual Meeting, Fort Lauderdale, Florida, 2003. Published Ribeiro, M.L.; Lobo, C.L.; Figueira, J.P.; Soares, M.A.; Marques, M.G.; Bernardes, R.C.; Cunha-Vaz, J.G.. "Correlation between progression of retinopathy and metabolic control in a two-year follow-up study of mild nonproliferative retinopathy in subjects with type 2 diabetes". Paper presented in ARVO Annual Meeting, Fort Lauderdale, Florida, 2003. Published Bernardes, R.C.; Lobo, C.; Cunha-Vaz, J.. "Retinal leakage analyzer. New developments in instrumentation and data processing". Paper presented in ARVO Annual Meeting, Fort Lauderdale, Florida, 2002. Published Lobo, C.F.; Bernardes, R.B.; De Abreu, J.R.F.; Cunha-Vaz, J.G.. "Two years evolution of alterations of the blood retinal barrier and retinal thickness in type 2 mild non-proliferative diabetic retinopathy.". Paper presented in ARVO Annual Meeting, Fort Lauderdale, Florida, 2001. Published Bernardes, R.C.; Lobo, C.; Barros, C.; Cunha-Vaz, J.G.; BERNARDES, R; LOBO C; BARROS C; CUNHA-VAZ, J. "New methodologies for multimodal macula mapping.". Paper presented in ARVO2001, Alicante, 2001. Published CUNHAVAZ JG; LOBO C; BERNARDES R; DEABREU JRF. "One-Year Evolution Of Alterations Of The Blood-Retinal Barrier and Retinal Thickness In Type-2 Mild Nonproliferative Diabetic-Retinopathy". Paper presented in ARVO Annual Meeting, Fort Lauderdale, Florida, 2000. Published Bernardes, R.C.; Lobo, C.; De Abreu, J.R.F.; Cunha-Vaz, J.G.. "Microaneurysms and degree of alteration of the blood-retinal barrier in type 2 mild nonproliferative diabetic retinopathy.". Paper presented in ARVO Annual Meeting, Fort Lauderdale, Florida, 2000. Published BERNARDES R; LOBO C; CUNHAVAZ JG. "Multimodality Imaging of The Eye Fundus Integration of Retinal Thickness And Retinal Leakage Maps With Fundus Imaging Data". Paper presented in ARVO Annual Meeting, Fort Lauderdale, Florida, 1999. Published LOBO C; BERNARDES R; CUNHAVAZ JG. "Alterations of The Blood-Retinal Barrier And Retinal Thickness In The Initial-Stages of Type-2 Diabetic-Retinopathy". Paper presented in ARVO Annual Meeting, Fort Lauderdale, Florida, 1999. Published
Conference paper	Jordão, João; Quental, Hugo; Morgado, Miguel; Figueira, João; Castro-Farías, Daniela; DeBuc, Delia Cabrera; Castelo-Branco, Miguel; Paques, Michel; Bernardes, Rui. "Neurovascular coupling reflex - Contralateral stimulation apparatus and setup". Paper presented in IEEE 7th Portuguese Meeting on Bioengineering (ENBENG), 2023. Published • 10.1109/enbeng58165.2023.10175365 Correia, Carlos; Batista, Ana; Barbeiro, Sílvia; Cardoso, João; Domingues, José P.; Henriques, Rafael; Loureiro, Custódio; et al. "Time-dependent elastic numerical model for Optical Coherence Elastography of the murine retina". 2023. Published • 10.1109/enbeng58165.2023.10175350 Bernardo, Rita; Domingues, José Paulo; Bernardes, Rui; Morgado, António Miguel; Batista, Ana. "Evaluation of skin care products using optical coherence elastography". 2023. 10.1117/12.2648348 Bernardes, Rui; Ferreira, Hugo; Guimarães, Pedro; Serranho, Pedro. "Shedding Light on Early Central Nervous System Changes for Alzheimer’s Disease through the Retina: An Animal Study". 2022. 10.5220/0011125600003209 Bernardes, R.. "Textural information from the retinal nerve fibre layer in multiple sclerosis". 2019. 10.1109/enbeng.2019.8692454 Bernardes, R.; Nunes, Ana; Ambrosio, Antonio F.; Castelo-Branco, Miguel; Bernardes, Rui. "Texture Biomarkers of Alzheimer's Disease and Disease Progression in the Mouse Retina". Paper presented in EEE 18th International Conference on Bioinformatics and Bioengineering (BIBE), 2018. Published • 10.1109/bibe.2018.00016 Domingues, Jose P.; Silva, Susana F.; Loureiro, Custodio F. M.; Bernardes, Rui; Morgado, A.M.; Clemencio, Filomena M. C.. "Data acquisition and laser scanning synchronism in SS-OCT — An experimental apparatus". Paper presented in 2017 IEEE 5th Portuguese Meeting on Bioengineering (ENBENG), Coimbra, Portugal, 2017. Published • 10.1109/ENBENG.2017.7889426 Bernardes, Rui; Silva, Gilberto; Chiquita, Samuel; Serranho, Pedro; Ambrósio, António Francisco. "Retinal biomarkers of Alzheimer's Disease: insights from transgenic mouse models". 2017. 10.1007/978-3-319-59876-5_60 Santos, Miriam; Araujo, Aderito; Barbeiro, Silvia; Caramelo, Francisco; Correia, Antonio; Marques, Maria Isabel; Pinto, Luis; et al. "Simulation of cellular changes on Optical Coherence Tomography of human retina". Paper presented in 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Milan, 2015. Published • 10.1109/EMBC.2015.7320285 Santos, Miriam; Araujo, Aderito; Barbeiro, Silvia; Caramelo, Francisco; Correia, Antonio; Marques, Maria Isabel; Morgado, Miguel; et al. "Maxwell's equations based 3D model of light scattering in the retina". Paper presented in 2015 IEEE 4th Portuguese Meeting on Bioengineering (ENBENG), Porto, Portugal, 2015. Published • 10.1109/ENBENG.2015.7088869 António L. Correia; Luis Pinto; Adérito Araújo; Sílvia Barbeiro; Francisco Caramelo; Paulo Menezes; Miguel Morgado; Pedro Serranho; Rui Bernardes. "Monte Carlo Simulation of Diabetic Macular Edema Changes on Optical Coherence Tomography Data". Paper presented in Biomedical and Health Informatics International Conference, Valencia, Spain, 2014. Published • 10.1109/BHI.2014.6864466 Ana Sílvia C. Silva; João Figueira; Sílvia Simão; Nuno Gomes; Carlos Neves; Angelina Meireles; Natália Ferreira; Rui Bernardes. "Unveiling Preclinical Idiopathic Macular Hole Formation Using Support Vector Machines". Paper presented in Biomedical and Health Informatics International Conference, Valencia, Espanha, 2014. Published Bernardes, R.; Guimarães, P.; Rodrigues, P.; Serranho, P.. "Fully-Automatic Multimodal Co-Registration of Retinal Fundus Images". Paper presented in The International Conference on Health Informatics:, Vilamoura, 2013. Published • 10.1007/978-3-319-03005-0_63 Silva, SF; Domingues, JP; Agnelo, J.; Oliveira, J.; Morgado, M.; Bernardes, R.. "Development of an Optical Coherence Tomograph (OCT) for small animal retinal imaging". Paper presented in 2013 IEEE 3rd Portuguese Meeting in Bioengineering (ENBENG), Braga, 2013. Published • 10.1109/ENBENG.2013.6518404 Silva, Ana Silvia F. C.; Correia, Antonio L.. "From optical coherence tomography to Maxwell's equations". Paper presented in 2013 IEEE 3rd Portuguese Meeting in Bioengineering (ENBENG), Braga, Portugal, 2013. Published • 10.1109/ENBENG.2013.6518419 Adérito Araújo; Sílvia Barbeiro; Luis Pinto; António L. Correia; Miguel Morgado; Pedro Serranho; Rui Bernardes; et al. "Numerical Solution of time-dependent Maxwell's Equations for modelling scattered electromagnetic wave's propagation". Paper presented in 13th International Conference on Computational and Mathematical Methods, Almeria, Espanha, 2013. Published Rodrigues, P.; Guimarães, P.; Serranho, P.; Bernardes, R.. "Retinal Vascular Network from Optical Coherence Tomography". Paper presented in V IBILI Meeting, Coimbra, 2013. Published Rodrigues, P.; Serranho, P.; Bernardes, R.. "3D Nonlinear Complex-Diffusion Filter on GPU". Paper presented in 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), San Diego, CA, USA, 2012. Published • 10.1109/EMBC.2012.6345883 Santos, T.; Ribeiro, L.; Lobo, C.; Bernardes, R.; Serranho, P.. "Validation of the automatic identification of eyes with diabetic retinopathy by OCT". Paper presented in 2012 IEEE 2nd Portuguese Meeting in Bioengineering (ENBENG), Coimbra, 2012. Published • 10.1109/ENBENG.2012.6331373 Guimarães, P.; Rodrigues, P.; Serranho, P.; Bernardes, R.. "3D Retinal Vascular Network from Optical Coherence Tomography Data". Paper presented in 9Th annual International Conference on Image Analysis and Recognition (ICIAR2012), Aveiro, 2012. Published Serranho, P.; Guimarães, P.; Rodrigues, P.; Bernardes, R.. "On the Relevance of the 3D Retinal Vascular Network from OCT Data". Paper presented in 6Th Workshop on Statistics, Mathematics and Computation and 3rd Portuguese-Polish Workshop on Biometry, Covilhã, 2012. Published Guimarães, P.; Rodrigues, P.; Bernardes, R.; Serranho, P.. "3D Blood Vessels Segmentation from Optical Coherence Tomography". Paper presented in EVER 2012, Nice, 2012. Published Rodrigues, P.; Guimarães, P.; Bernardes, R.; Serranho, P.. "Vascular Network of the Human Macula from OCT". Paper presented in EVER 2012, Nice, 2012. Published Rodrigues, P.; Guimarães, P.; Serranho, P.; Bernardes, R.. "3D Vascular Network of the Ocular Fundus from SD-OCT". Paper presented in 4th Annual Meeting of IBILI, Coimbra, 2012. Published Bernardes, R.. "3D VascularNetwork of the Human Macula from Optical Coherence Tomography". Paper presented in Retinal Imaging Treatment and Analysis (RITA), Paris, 2012. Published Bernardes, Rui C.; Lobo, Conceição L.; Cunha-Vaz, José G.. "Measuring Retinal Fluorescein Leakage into the Human Vitreous with a Modified Confocal Scanning Laser Ophthalmoscope". 2012. Maduro, C.; Bernardes, R.; Serranho, P.; Santos, T.; Cunha-Vaz, J.. "OCT noise despeckling using a 3D nonlinear complex diffusion filter". Paper presented in 6th International Conference on Technology and Medical Sciences, Porto, Portugal, 2011. Published • 10.1201/b11330-40 Santos, T.; Bernardes, R.; Santos, A.; Cunha-Vaz, J.. "Noninvasive Assessment of Blood-Retinal Barrier Function by High-Definition Optical Coherence Tomography". Paper presented in 6th International Conference on Technology and Medical Sciences, Porto, 2011. Published • 10.1201/b11330-40 Bernardes, R.. "Optical coherence tomography: Health information embedded on OCT signal statistics.". Paper presented in 2011 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Boston, MA, 2011. Published • 10.1109/IEMBS.2011.6091514 Bernardes, Rui; Maduro, Cristina; Serranho, Pedro; Dinis, João; Cunha-Vaz, José. "Adaptive complex diffusion noise despeckling for 3D OCT Data". 2011. Serranho, Pedro; Maduro, Cristina; Santos, Torcato; Bernardes, Rui; Vaz, José Cunha; Araújo, Adérito; Barbeiro, Sílvia; et al. "Ocular fundus Imaging: from structure to function". Paper presented in 1st Portuguese Meeting in Bioengineering - The Challenge of the XXI Century (ENBENG), Lisbon, Portugal, 2011. Published • 10.1109/ENBENG.2011.6026080 Serranho, P.; Maduro, C.; Santos, T.; Cunha-Vaz, J.; Bernardes, R.. "Synthetic OCT data for image processing performance testing". Paper presented in 18TH IEEE INTERNATIONAL CONFERENCE ON IMAGE PROCESSING (ICIP), Bruxelas, 2011. Published • 10.1109/icip.2011.6116534 Santos, T.; Bernardes, R.; Santos, A.; Cunha-Vaz, J.. "Noninvasive assessment of Blood-Retinal Barrier function by High-Definition Optical Coherence Tomography". Paper presented in The 6th International Conference on Technology and Medical Sciences, Porto, 2010. Published Bernardes, R.; Santos, T.; Cunha-Vaz, J.. "Evaluation of blood-retinal barrier function from Fourier domain high-definition optical coherence tomography". Paper presented in World Congress on Medical Physics and Biomedical Engineering, Munique, 2009. Published • 10.1007/978-3-642-03891-4-84 Bernardes, R.; Santos, T.; Cunha-Vaz, J.. "Evaluation of Blood-Retinal Barrier Function from Fourier Domain High-Definition Optical Coherence Tomography.". Paper presented in World Congress on Medical Physics and Biomedical Engineering, Munich, Germany, 2009. Published • 10.1007/978-3-642-03891-4_84 Bernardes, R.; Cunha-Vaz, J.. "Perspectives for multimodal imaging of the retina in disease". Paper presented in 8th EURETINA Congress, Vienna, Austria, 2008. Published Baptista, P.; Ferreira, J.; Bernardes, R.; Dias, J.; Cunha-Vaz, J.. "Multimodal macula mapping by deformable image registration". Paper presented in CompIMAGE - Computational Modeling of Objects Represented in Images - Fundamentals, Methods and Applications, Coimbra, 2006. Published Baptista, P.; Ferreira, J.; Bernardes, R.; Dias, J.; Cunha-Vaz, J.. "Multimodal Macula Mapping by Deformable Image Registration". Paper presented in CompIMAGE'2006 Symposium - Computational Modeling of Objects Represented in Images: Fundamentals, Coimbra, 2006. Published Baptista, P.; Bernardes, R.; Ferreira, J.; Dias, J.; Cunha-Vaz, J.. "Multimodal macula mapping: study for rigid, perspective and deformable image registration". Paper presented in The 3rd European Medical and Biological Engineering Conference (EMBEC’05), Prague, Czech Republic, 2005. Published Bernardes, R.; Ferreira, J.; Baptista, P.; Sebastião, A.; Dias, J.; Cunha-Vaz, J.. "Distortion free registration between multifocal ERG and retinal leakage analyzer". Paper presented in 3rd European Medical and Biological Engineering Conference, Prague, Czech Republic, 2005. Published Ferreira, JF; Bernardes, R.; Baptista, P.; Dias, J.; Cunha-Vaz, J.. "Earmarking Retinal Changes in a Sequence of Digital Color Fundus Photographs". Paper presented in The 3rd European Medical and Biological Engineering Conference (EMBEC’05), Praga, 2005. Published Bernardes, R.; Ferreira, JF; Baptista, P.; Sebastião, A.; Dias, J.; Cunha-Vaz, J.. "Functional and morphological retinal data fusion". Paper presented in The 3rd European Medical and Biological Engineering Conference (EMBEC’05), Praga, 2005. Published Bernardes, R.; Baptista, P.; Cunha-Vaz, J.; Dias, J.; Cunha-Viaz, J.. "Multimodal functional and morphological nonrigid image registration". Paper presented in 2005 International Conference on Image Processing, Genova, Italy, 2005. Published • 10.1109/ICIP.2005.1529955 Cunha-Vaz, J.; Bernardes, R.. "Multimodal Macula Mapping: Characterization of Phenotypes of Diabetic Retinopathy". Paper presented in "The International Symposium of Ocular Pharmacology and Therapeutics" (ISOPT), Monte Carlo, Monaco, 2004. Published Bernardes, R.; Figueira, J.; Lobo, C.; Cunha-Vaz, J.. "Mapping Clinically Significant Diabetic Macular Edema. Comparison Between Stereofundus Photography, RTA and OCT". Paper presented in 5th International Symposium on Ocular Pharmacology and Therapeutics, Monte Carlo, 2004. Published Bernardes, R.; Lobo, C.; Dias, J.; Cunha-Vaz, J.. "New Instrumentation For Blood-Retinal Barrier Permeability Analysis". Paper presented in The 2nd European Medical & Biological Engineering Conference (EMBEC'02), Viena, 2002. Published Bernardes, R.; Isidoro, J.; Simões, P.; Lobo, C.; Cunha-Vaz, JG; Cunha-Vaz, J.. "Measuring retinal fluorescein leakage into the human vitreous with modified confocal scanning laser ophthalmoscope". Paper presented in European Society of Engineering and Medicine, ., 1999. Published
Conference poster	Cravo, Maria Inês; Bernardes, R.; Castelo-Branco, Miguel. "The impact of neuronal noise statistics on binocular rivalry dynamics". Paper presented in CNS 2021 - Annual Computational Neuroscience Meeting, 2021. Lima, C.; Varela, R.; Otília d'Almeida; Alves, C.; Bernardes, R.; Santana, I.; Castelo-Branco, Miguel; Sousa, L.. "The role of optical coherence tomography as a predictor of cognitive impairment in multiple sclerosis". Paper presented in Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), 2018. 10.1177/1352458518798592 Duque, Cristina; Januário, Cristina; Lemos, João; Fonseca, P.; Correia, Antonio; Ribeiro, L.; Bernardes, R.; Freire, António. "Optical coherence tomography in LRRK2-associated Parkinson Disease". Paper presented in American Academy of Neurology (AAN 2015), 2015. Bernardes, R.; Guimarães, P.; Rodrigues, P.; Lobo, C.; Serranho, P.. "Multimodal co-registration of ocular fundus images". Paper presented in 3rd Portuguese Bioengineering Meeting, 2013. Rodrigues, P.; Guimarães, P.; Bernardes, R.; Serranho, P.. "Improved 3-Dimension Retinal Vascular Tree Segmentation and Reconstruction from HD-OCT". Paper presented in ARVO 2013 Annual Meeting, 2013. Bernardes, R.; Santos, T.; Serranho, P.; Horne, M.; Durbin, M.; Cunha-Vaz, J.. "Information on Neuronal Ageing from OCT Evaluation of the Retina". Paper presented in ARVO 2012 Annual Meeting, 2012. Bernardes, R.; Santos, T.. "Optical Coherence Tomography: signal signature on neuronal ageing and blood-retinal barrier status". Paper presented in 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2012. Rodrigues, P.; Bernardes, R.. "3D Adaptive Nonlinear Complex-Diffusion Filtering on GPU". Paper presented in 4th Annual Meeting of IBILI, 2012. Guimarães, P.; Rodrigues, P.; Bernardes, R.; Serranho, P.. "Vascular Network of the Human Macula from High-Definition OCT". Paper presented in ARVO 2012 Annual Meeting, 2012. Guimarães, P.; Rodrigues, P.; Serranho, P.; Lobo, C.; Bernardes, R.. "Multi-modal co-registration of fundus images". Paper presented in 4th Annual Meeting of IBILI, 2012. Rodrigues, P.; Guimarães, P.; Serranho, P.; Bernardes, R.. "3D Retinal Vascular Network from OCT Data". Paper presented in ARVO 2012 Annual Meeting, 2012. Santos, T.; Horne, M.; Durbin, M.; Bernardes, R.; Cunha-Vaz, J.. "Automatic Identification of eyes with Diabetic Retinopathy by OCT". Paper presented in ARVO 2012 Annual Meeting, 2012. Santos, T.; Bernardes, R.. "Optical Coherence Tomography: signal signature on neuronal ageing and blood-retinal barrier status". Paper presented in 4th Annual Meeting of IBILI, 2012. Guimarães, P.; Serranho, P.; Castelo-Branco, M.; Bernardes, R.. "Segmentation Process and Pattern Recognition in Retina and Brain Imaging". Paper presented in 2nd Portuguese BioEngineering Meeting, 2012. Guimarães, P.; Rodrigues, P.; Serranho, P.; Bernardes, R.. "3D Retinal Vascular Network from Optical Coherence Tomography data". Paper presented in 3rd Annual Meeting of IBILI, 2011. Pereira, H.; Alfaiate, M.; Santos, T.; Pedrosa, L.; Mendes, M.; Venâncio, R.; Figueira, J.; Bernardes, R.. "Identification of Eyes at Risk of Developing Idiopathic Macular Holes by Support Vector Machines". Paper presented in IBILI Meeting, 2011. Bernardes, R.; Maduro, C.; Serranho, P.; Dinis, J.; Rodrigues, P.; Cunha-Vaz, J.. "Adaptive complex diffusion noise despeckling for 3D OCT data". Paper presented in ARVO 2011 Annual Meeting, 2011. Serranho, P.; Rodrigues, P.; Bernardes, R.. "Optical Coherence Tomography Data Analysis by Support Vector Machines". Paper presented in 11th Annual Meeting of the European Network for Business and Industrial Statistics (ENBIS), 2011. Santos, T.; Rodrigues, P.; Guimarães, P.; Gonçalves, V.; Cunha-Vaz, J.; Bernardes, R.. "Assessing the Ageing of Neuronal Tissue Through OCT". Paper presented in 3rd Annual Meeting of IBILI, 2011. Rodrigues, P.; Guimarães, P.; Bernardes, R.; Serranho, P.. "Retinal Vascular Network From 2D OCT Fundus Images". Paper presented in 3rd Annual Meeting of IBILI, 2011. Pereira, H.; Alfaiate, M.; Santos, T.; Pedrosa, L.; Mendes, M.; Venâncio, R.; Figueira, J.; Bernardes, R.. "Identification of eyes at risk of deveolping Idiopathic Macular Holes by Support Vector Machines". Paper presented in 3rd Annual Meeting of IBILI, 2011. Serranho, P.; Bernardes, R.; Maduro, C.; Santos, T.; Cunha-Vaz, J.. "Synthetic Volume from real Optical Coherence Tomography data". Paper presented in ARVO 2011 Annual Meeting, 2011. Maduro, C.; Santos, T.; Serranho, P.; Araújo, A.; Barbeiro, S.; Cunha-Vaz, J.; Bernardes, R.. "Improved nonlinear complex diffusion filter for speckle reduction". Paper presented in 2nd Annual Meeting of IBILI, 2011. Bernardes, R.; Santos, T.; Santos, A.; Lobo, C.; Cunha-Vaz, J.. "Blood-retinal Barrier Function Assessment Using High-definition Spectral Domain OCT". Paper presented in 2010 ISIE/Imaging Conference, 2010. Almeida, O.; Mateus, C.; Bernardes, R.; Castelo-Branco, M.. "Structural and structure-function correlations in neurodevelopmental disorders of the visual system". Paper presented in II IBILI Meeting, 2010. Guimarães, P.; Serranho, P.; Almeida, O.; Castelo-Branco, M.; Bernardes, R.. "Correlation between retinal and cortical thickness". Paper presented in II IBILI Meeting, 2010. Maduro, C.; Bernardes, R.; Santos, T.; Cunha-Vaz, J.. "3D Expansion of Complex Diffusion Filter for OCT Noise Despeckling". Paper presented in ARVO 2010 Annual Meeting, 2010. Bernardes, R.; Santos, T.; Horne, M.; Cunha-Vaz, J.. "Non-invasive assessment of blood-retinal barrier changes by Cirrus HD-OCT". Paper presented in ARVO 2009 Annual Meeting, 2009. Maduro, C.; Serranho, P.; Bernardes, R.; Cunha-Vaz, J.. "High definition OCT: Despeckling and Segmentation". Paper presented in 1st IBILI Annual Meeting 2009, 2009. Santos, T.; Bernardes, R.; Cunha-Vaz, J.. "Non-invasive assessment of blood-retinal barrier changes by Cirrus HD-OCT". Paper presented in 1st IBILI Annual Meeting 2009, 2009. Schwartz, A.; Bernardes, R.; Carvajal-Gonzalez, S.; Jolin, L.; Moore, D.; Chakravarthy, U.; Staurenghi, G.; Coscas, G.; Cunha-Vaz, J.. "An Instrument performance survey of HRA Spectralis Scanning Laser ophthalmoscopes using quantitative standards for fluorescein, ICG and Autofluorescense". Paper presented in ARVO 2009 Annual Meeting, 2009. Pires, I.; Duarte, L.; Nunes, S.; Pereira, I.; Bernardes, R.; Cunha-Vaz, J.. "Microaneurysms formation rate as a predictor of DR progression to CSME needing photocoagulation in nonproliferative retinopathy in diabetes type 2". Paper presented in ARVO 2009 Annual Meeting, 2009. Pereira, I.; Nunes, S.; Ribeiro, L.; Duarte, L.; Santos, A.; Bernardes, R.; Cunha-Vaz, J.. "Weak correlation between retinal thickness and BCVA in CSME eyes of patients with diabetes type 2". Paper presented in ARVO 2009 Annual Meeting, 2009. Santos, T.; Bernardes, R.; Cunha-Vaz, J.. "Automated detection of macular changes in dry AMD using the Retmarker". Paper presented in ARVO 2009 Annual Meeting, 2009. Nunes, S.; Pereira, I.; Bernardes, R.; Pires, I.; Duarte, L.; Cunha-Vaz, J.. "A new method for semi-automated measurements of microaneurysms formation rate form color fundus photographs in diabetic retinopathy". Paper presented in ARVO 2009 Annual Meeting, 2009. Bernardes, R.; Silva, R.; Nunes, S.; Fonseca, P.; Santos, A.; Carvajal-Gonzalez, S.; Buggage, R.; Cunha-Vaz, J.. "Alteration of the Blood-Retinal Barrier Identified by Retinal Leakage Analysis is a Predictor for Conversion to Wet Age-Related Macular Degeneration". Paper presented in ARVO 2008 Annual Meeting, 2008. Bernardes, R.; Nunes, S.; Santos, A.; Pereira, I.; Cunha-Vaz, J.. "Retinal Thickness vs. Retinal Sensitivity at the Central Human Macula". Paper presented in EVER 2008 Congress, 2008. Silva, R.; Nunes, S.; Bernardes, R.; Fonseca, P.; Santos, A.; Carvajal-Gonzalez, S.; Buggage, R.; Cunha-Vaz, J.. "Retinal Edema Identified by Optical Coherence Tomography Is a Reliable Indicator of Conversion to Wet Age-Related Macular Degeneration". Paper presented in ARVO 2008 Annual Meeting, 2008. Fonseca, P.; Santos, A.; Bernardes, R.; Silva, R.; Carvajal-Gonzalez, S.; Buggage, R.; Cunha-Vaz, J.. "Fundus Autofluorescence Patterns Do Not Correlate With Development of Choroidal Neovascularization in Fellow Eyes of Patients With Neovascular Age-Related Macular Degeneration". Paper presented in ARVO 2008 Annual Meeting, 2008. Schwartz, A.; Jolin, L.; Snow, E.; Franke, S.; Marques, C.; Bernardes, R.. "Stabilizing Indocyanin Green for Use as Quantitative Standards". Paper presented in ARVO 2008 Annual Meeting, 2008. Buggage, R.; Silva, R.; Bernardes, R.; Nunes, S.; Fonseca, P.; Cunha-Vaz, J.. "Baseline Characteristics of Study Eyes Enrolled in a Longitudinal, Observational Study to Identify the Early Markers of Choroidal Neovascularization". Paper presented in ARVO 2008 Annual Meeting, 2008. Bernardes, R.; Morgado, A.; Baptista, P.; Schwartz, A.; Verdugo-Gazdik, M.; Carter, W.; Cunha-Vaz, J.. "Instrumentation Adaptation for Quantitative Fluorescein Angiograms". Paper presented in ARVO 2007 Annual Meeting, 2007. Schwartz, A.; Marques, C.; Abreu, G.; Bernardes, R.; Jolin, L.; Snow, E.; Wang, L.; et al. "Quantitative Characteristics of Fluorescein for Fluorescence Angiograms". Paper presented in ARVO 2007 Annual Meeting, 2007. Rosa, A.; Baptista, P.; Santos, A.; Soares, M.; Bernardes, R.; Schwartz, A.; Verdugo-Gazdik, M.; Carter, W.; Cunha-Vaz, J.. "Quantitative Fluorescein Angiograms". Paper presented in ARVO 2007 Annual Meeting, 2007. Santos, Ana Rita; Duarte, L.; Geraldes, E.; Nunes, S.; Bernardes, R.; Cunha-Vaz, José. "Risk Markers for the Development of Severe Macular Edema Needing Photocoagulation in Mild Nonproliferative Retinopathy in Type 2 Diabetes. A Seven Year Follow¿Up". Paper presented in ARVO 2006, 2006. Bernardes, R.; Baptista, P.; Dinis, J.; Cunha-Vaz, J.. "Multimodal functional and morphological nonrigid image registration". Paper presented in V Congresso de Investigação em Medicina, 2006. Bernardes, R.; Baptista, P.; Ferreira, J.; Duarte, L.; Cunha-Vaz, J.. "Earmarking retinal changes on a color fundus photograph time-sequence". Paper presented in ARVO 2006 Annual Meeting, 2006. Nunes, S.; Bernardes, R.; Duarte, L.; Cunha-Vaz, J.. "Identification of different phenotypes of mild non-proliferative retinopathy of type 2 diabetes using cluster and discriminant mathematical analysis". Paper presented in ARVO 2006 Annual Meeting, 2006. Baptista, P.; Santos, T.; Bernardes, R.; Cunha-Vaz, J.. "Increased OCT mapping resolution by merging line and circle scan types". Paper presented in ARVO 2006 Annual Meeting, 2006. Bernardes, R.; Baptista, P.; Dias, J.; Cunha-Vaz, J.. "Multimodal Functional and Morphological Nonrigid Image Registration". Paper presented in 12th International Conference on Image Processing (ICIP), 2005. Bernardes, R.; Baptista, P.; Ferreira, J.; Dias, J.; Cunha-Vaz, J.. "Registration of functional and morphological imaging modalities". Paper presented in 15th meeting of the EASD Eye Complications Study Group (EASDec), 2005. Bernardes, R.; Nunes, S.; Duarte, L.; Cunha-Vaz, J.. "Comparison between retinal edema by color fundus photography and retinal thickness maps". Paper presented in ARVO 2005 Annual Meeting, 2005. Bernardes, R.; Ferreira, J.; Baptista, P.; Cunha-Vaz, J.. "Earmarking retinal changes in a sequence of digital color fundus photographs". Paper presented in ISIE - 3rd Annual Meeting, 2005. Ferreira, J.; Bernardes, R.; Baptista, P.; Cunha-Vaz, J.. "Earmarking retinal changes in a sequence of digital color fundus photographs". Paper presented in 15th meeting of the EASD Eye Complications Study Group (EASDec), 2005. Baptista, P.; Bernardes, R.; Dias, J.; Cunha-Vaz, J.. "Automatic Establishment of Macular Coordinates". Paper presented in 15th meeting of the EASD Eye Complications Study Group (EASDec), 2005. Bernardes, R.. "Comparison between retinal edema by color fundus photography and retinal thickness maps". Paper presented in Dia do Centro de Oftalmologia / V Jornadas Internacionais de Oftalmologia, 2005. Baptista, P.; Bernardes, R.; Ferreira, J.; Dias, J.; Cunha-Vaz, J.. "Multimodal macula mapping: study for rigid, perspective and deformable image registration". Paper presented in 3rd European Medical and Biological Engineering Conference EMBEC'05, 2005. Nunes, S.; Bernardes, R.; Torrent-Solans, T.; Soares, M.; Cunha-Vaz, J.. "Retinal thickness measurements: RTA I vs RTA II, OCT II vs Stratus OCT and RTA II vs Stratus OCT in normal eyes". Paper presented in ARVO 2004 Annual Maeeting, 2004. Duarte, LG; Bernardes, R.; Soares, MA; Lobo, C.; Abreu, JF; Cunha-Vaz, JG. "Retinopathy Phenotypes in Diabetes type 2. Patterns of retinopathy progression in a two-year folow-up". Paper presented in ARVO 2004 Annual Meeting, 2004. Bernardes, R.; Monteiro, R.; Lobo, C.; Cunha-Vaz, J.. "OCT Increased resolution retinal thickness mapping". Paper presented in ARVO 2003 annual Meeting, 2003. Duarte, LG; Lobo, C.; Bernardes, R.; Soares, MA; Figueira, JP; Abreu, JF; Cunha-Vaz, JG. "Macular maps of fluorescein leakage during a 3-year follow-up in patients with type 2 Diabetes Mellitus and Mild Non-proliferative Retinopathy". Paper presented in ARVO 2003 Annual Meeting, 2003. Monteiro, R.; Bernardes, R.; Almeida, E.; Lobo, C.; Cunha-Vaz, J.. "Reability of the RTA for Detecting Changes in Retinal Thickness in Preclinical Retinopathy in Subjects with Type 2 Diabetes". Paper presented in ARVO 2003 Annual Meeting, 2003. Ribeiro, ML; Lobo, CL; Soares, MA; Marques, MG; Bernardes, R.; Cunha-Vaz, JG. "Correlation between Progression of Retinopathy and Metabolic Control in a Two-year Follow-up Study of Mild Nonproliferative Retinopathy in Subjects with Type 2 Diabetes.". Paper presented in ARVO 2003 Annual Meeting, 2003. Bernardes, R.; Lobo, C.; Cunha-Vaz, J.. "Retinal leakage analyzer. New developments in instrumentation and data processing.". Paper presented in ARVO 2002 Annual Meeting, 2002. Figueira, J.; Bernardes, R.; Pires, I.; Soares, M.; Lobo, C.; Cunha-Vaz, J.. "Mapping Clinically Significant Diabetic Macular Edema. Comparison between Stereofundus Photography, RTA and OCT". Paper presented in ARVO 2002 Annual Meeting, 2002. Ludovico, J.; Pires, I.; Bernardes, R.; Lobo, C.; Cunha-Vaz, J.. "Alterations of Retinal Capillary Blood-flow In Preclinical Retinopathy In Subjects with Type 2 Diabetes". Paper presented in ARVO 2002 Annual Meeting, 2002. Bernardes, R.; Santos, F.; Lobo, C.; Cunha-Vaz, J.. "Mapping Fluorescein Leakage Across the BRB Using a Modified Confocal Scanning Laser Ophthalmoscope". Paper presented in ARVO 1998 Annual Meeting, 1998.
Edited book	Bernardes, R.; Cunha-Vaz, J.. Optical Coherence Tomography. A Clinical and Technical Update. Berlin, Heidelberg, Germany: Springer Berlin Heidelberg. 2012. Published • Editor
Journal article	Franziska G. Rauscher; Rui Bernardes. "Retinale optische Kohärenztomographie Biomarker und ihr Zusammenhang mit kognitiven Funktionen". Die Ophthalmologie (2024): https://doi.org/10.1007/s00347-024-01985-y. 10.1007/s00347-024-01985-y Guimarães, Pedro; Serranho, Pedro; Duarte, João V.; Crisóstomo, Joana; Moreno, Carolina; Gomes, Leonor; Bernardes, Rui; Castelo-Branco, Miguel. "The hemodynamic response function as a type 2 diabetes biomarker: a data-driven approach". Frontiers in Neuroinformatics 17 (2024): http://dx.doi.org/10.3389/fninf.2023.1321178. 10.3389/fninf.2023.1321178 Ana Nunes; Pedro Serranho; Pedro Guimarães; João Ferreira; Miguel Castelo-Branco; Rui Bernardes. "When Sex Matters: Differences in the Central Nervous System as Imaged by OCT through the Retina". Journal of Imaging (2023): https://doi.org/10.3390/jimaging10010006. 10.3390/jimaging10010006 Cravo, Maria Inês; Bernardes, Rui; Castelo-Branco, Miguel. "Subtractive adaptation is a more effective and general mechanism in binocular rivalry than divisive adaptation". Journal of Vision 23 7 (2023): 18. http://dx.doi.org/10.1167/jov.23.7.18. 10.1167/jov.23.7.18 Ana Batista; Pedro Serranho; Mário J. Santos; Carlos Correia; José P. Domingues; Custódio Loureiro; João Cardoso; et al. "Phase-Resolved Optical Coherence Elastography: An Insight into Tissue Displacement Estimation". Sensors (2023): https://doi.org/10.3390/s23083974. 10.3390/s23083974 Ana Batista; Pedro Guimarães; João Martins; Paula I. Moreira; António Francisco Ambrósio; Miguel Castelo-Branco; Pedro Serranho; Rui Bernardes. "Normative mice retinal thickness: 16-month longitudinal characterization of wild-type mice and changes in a model of Alzheimer's disease". Frontiers in Aging Neuroscience 15 (2023): http://dx.doi.org/10.3389/fnagi.2023.1161847. 10.3389/fnagi.2023.1161847 Ana Batista; Pedro Guimarães; Pedro Serranho; Ana Nunes; João Martins; Paula I. Moreira; António Francisco Ambrósio; et al. "Retinal imaging in animal models: Searching for biomarkers of neurodegeneration". Frontiers in Ophthalmology 3 (2023): http://dx.doi.org/10.3389/fopht.2023.1156605. 10.3389/fopht.2023.1156605 Lapo Pais, Marta; Jorge, Lília; Martins, Ricardo; Canário, Nádia; Xavier, Ana Carolina; Bernardes, Rui; Abrunhosa, Antero; Santana, Isabel; Castelo-Branco, Miguel. "Textural properties of microglial activation in Alzheimer’s disease as measured by (R)-[11C]PK11195 PET". Brain Communications 5 3 (2023): http://dx.doi.org/10.1093/braincomms/fcad148. 10.1093/braincomms/fcad148 Rui Bernardes. "Stage-independent biomarkers for Alzheimer's disease from the living retina: an animal study". Scientific Reports 12 1 (2022): http://dx.doi.org/10.1038/s41598-022-18113-y. 10.1038/s41598-022-18113-y Pedro Guimarães; Pedro Serranho; João Martins; Paula I. Moreira; António Francisco Ambrósio; Miguel Castelo-Branco; Rui Bernardes. "Retinal Aging in 3× Tg-AD Mice Model of Alzheimer's Disease". Frontiers in Aging Neuroscience (2022): https://app.dimensions.ai/details/publication/pub.1148723048. 10.3389/fnagi.2022.832195 Adérito Araújo; Sílvia Barbeiro; Rui Bernardes; Miguel Morgado; Suncica Sakic. "A mathematical model for the corneal transparency problem". Journal of Mathematics in Industry (2022): https://app.dimensions.ai/details/publication/pub.1147688118. 10.1186/s13362-022-00125-y Boia, Raquel; Dias, Paulo A.N.; Galindo-Romero, Caridad; Ferreira, Hugo; Aires, Inês D.; Vidal-Sanz, Manuel; Agudo-Barriuso, Marta; et al. "Intraocular implants loaded with A3R agonist rescue retinal ganglion cells from ischemic damage". Journal of Controlled Release 343 (2022): 469-481. http://dx.doi.org/10.1016/j.jconrel.2022.02.001. Open access • Published • 10.1016/j.jconrel.2022.02.001 Maryam Khaksar Ghalati; Ana Nunes; Hugo Ferreira; Pedro Serranho; Rui Bernardes. "Texture Analysis and Its Applications in Biomedical Imaging: A Survey". IEEE Reviews in Biomedical Engineering 15 (2022): 222-246. https://doi.org/10.1109/RBME.2021.3115703. 10.1109/RBME.2021.3115703 Ferreira, Hugo; Martins, João; Moreira, Paula I.; Ambrósio, António Francisco; Castelo-Branco, Miguel; Serranho, Pedro; Bernardes, Rui. "Longitudinal normative OCT retinal thickness data for wild-type mice, and characterization of changes in the 3×Tg-AD mice model of Alzheimer's disease". Aging 13 7 (2021): 9433-9454. http://dx.doi.org/10.18632/aging.202916. Open access • Published • 10.18632/aging.202916 Lapo Pais, M.; Jorge, L.; Martins, R.; Canario, N.; Xavier, C.; Abrunhosa, A.; Santana, I.; Bernardes, R.; Castelo-Branco, M.. "Texture Quantification Parameters for Alzheimer's disease diagnosis measured by 11C-(R)-PK11195 PET images". European Journal of Nuclear Medicine and Molecular Imaging (2021): https://publons.com/wos-op/publon/53665983/. Lília Jorge; Nádia Canário; Ricardo Martins; Beatriz Santiago; Isabel Santana; Hugo Quental; Francisco Ambrósio; Rui Bernardes; Miguel Castelo-Branco. "The Retinal Inner Plexiform Synaptic Layer Mirrors Grey Matter Thickness of Primary Visual Cortex with Increased Amyloid ß Load in Early Alzheimer’s Disease". Neural Plasticity (2020): https://doi.org/10.1155/2020/8826087. 10.1155/2020/8826087 Nunes, Ana; Serranho, Pedro; Quental, Hugo; Ambrósio, António F.; Castelo-Branco, Miguel; Bernardes, Rui. "Sexual dimorphism of the adult human retina assessed by optical coherence tomography". Health and Technology 10 4 (2020): 913-924. http://dx.doi.org/10.1007/s12553-020-00428-3. Published • 10.1007/s12553-020-00428-3 Ferreira, Hugo; Martins, João; Nunes, Ana; Moreira, Paula I.; Castelo-Branco, Miguel; Ambrósio, António Francisco; Serranho, Pedro; Bernardes, Rui. "Characterization of the retinal changes of the 3×Tg-AD mouse model of Alzheimer's disease". Health and Technology 10 4 (2020): 875-883. http://dx.doi.org/10.1007/s12553-020-00413-w. Open access • Published • 10.1007/s12553-020-00413-w Jorge, Lília; Canário, Nádia; Quental, Hugo; Bernardes, Rui; Castelo-Branco, Miguel. "Is the Retina a Mirror of the Aging Brain? Aging of Neural Retina Layers and Primary Visual Cortex Across the Lifespan". Frontiers in Aging Neuroscience 11 (2020): http://dx.doi.org/10.3389/fnagi.2019.00360. Published • 10.3389/fnagi.2019.00360 Rui Bernardes; Hugo Ferreira; João Martins; Paula I. Moreira; Miguel Castelo-Branco; António F. Ambrósio; Pedro Serranho. "Retinal thickness of the triple-transgenic mice model of Alzheimer\’s disease at the age of one month". Acta Ophthalmologica (2019): https://app.dimensions.ai/details/publication/pub.1123540934. 10.1111/j.1755-3768.2019.5467 Rui Bernardes. "Optical coherence tomography - machine learning". Acta Ophthalmologica (2019): https://app.dimensions.ai/details/publication/pub.1123536986. 10.1111/j.1755-3768.2019.5017 Alves, Carolina; Jorge, Lília; Canário, Nádia; Santiago, Beatriz; Santana, Isabel; Castelhano, João; Ambrósio, António Francisco; Bernardes, Rui; Castelo-Branco, Miguel. "Interplay Between Macular Retinal Changes and White Matter Integrity in Early Alzheimer’s Disease". Journal of Alzheimer's Disease 70 3 (2019): 723-732. http://dx.doi.org/10.3233/jad-190152. Open access • Published • 10.3233/jad-190152 Nunes, Ana; Silva, Gilberto; Duque, Cristina; Januário, Cristina; Santana, Isabel; Ambrósio, António Francisco; Castelo-Branco, Miguel; Bernardes, Rui. "Retinal texture biomarkers may help to discriminate between Alzheimer’s, Parkinson’s, and healthy controls". PLOS ONE 14 6 (2019): e0218826. http://dx.doi.org/10.1371/journal.pone.0218826. Published • 10.1371/journal.pone.0218826 Abuhaiba, Sulaiman I; Cordeiro, Miguel; Amorim, Andre; Cruz, Ângela; Quendera, Bruno; Ferreira, Carlos; Ribeiro, Luisa; Bernardes, Rui; Castelo-Branco, Miguel. "Occipital Blood brain barrier permeability is an independent predictor of visual outcome in type 2 diabetics, irrespective of the retinal barrier: a longitudinal study". Journal of Neuroendocrinology 1 30 (2018): 1-10. Published • 10.1111/jne.12566 Alves, Carolina; S. Batista; Otília d'Almeida; Lívia Sousa; Cunha, Luís; Bernardes, R.; Castelo-Branco, M.. "The retinal ganglion cell layer predicts normal-appearing white matter tract integrity in multiple sclerosis: A combined diffusion tensor imaging and optical coherence tomography approach". Human Brain Mapping 39 4 (2018): 1712-1720. Published • 10.1002/hbm.23946 Bernardes, R.; Silva, G.; Batista, S.; Sousa, L.; Castelo Branco, M.. "Macular changes in patients with multiple sclerosis - A texture analysis of optical coherence tomography data". Acta Ophthalmologica (2017): https://publons.com/wos-op/publon/42705738/. 10.1111/J.1755-3768.2017.01513 Guimarães, Pedro; Rodrigues, Pedro; Celorico, Dirce; Serranho, Pedro; Bernardes, Rui. "Three-dimensional segmentation and reconstruction of the retinal vasculature from spectral-domain optical coherence tomography". Journal of Biomedical Optics 20 1 (2015): 016006-016006. Published • 10.1117/1.JBO.20.1.016006 Guimarães, Pedro; Rodrigues, Pedro; Lobo, Conceição; Leal, Sérgio; Figueira, João; Serranho, Pedro; Bernardes, Rui. "Ocular fundus reference images from optical coherence tomography". Computerized Medical Imaging and Graphics 38 5 (2014): 381-389. Published • 10.1016/j.compmedimag.2014.02.003 Rodrigues, P.; Guimarães, P.; Santos, T.; Simão, S.; Miranda, T.; Serranho, P.; Bernardes, R.. "Two-dimensional segmentation of the retinal vascular network from optical coherence tomography". Journal of Biomedical Optics 18 12 (2013): 126011-126011. http://biomedicaloptics.spiedigitallibrary.org/article.aspx?articleid=1790514%20&journalid=93#Data. Published • 10.1117/1.JBO.18.12.126011 Serranho, P.; Guimarães, P.; Rodrigues, P.; Bernardes, R.. "On the relevance of the 3D retinal vascular network from OCT data". Biometrical Letters 49 2 (2012): 95-102. Published • 10.2478/bile-2013-0007 Rodrigues, P.; Bernardes, R.. "3-D Adaptive Nonlinear Complex-Diffusion Despeckling Filter". IEEE Transactions on Medical Imaging 31 12 (2012): 2205-2212. Published • 10.1109/TMI.2012.2211609 Bernardes,, Rui; Serranho, Pedro; Santos, Torcato; Gonçalves, Valter; Vaz, José Cunha. "Optical Coherence Tomography - Automatic Retina Classification Through Support Vector Machines". European Ophthalmic Review 06 04 (2012): 200. http://dx.doi.org/10.17925/eor.2012.06.04.200. Published • 10.17925/eor.2012.06.04.200 Bernardes, R.; Santos, T.; Serranho, P.; Lobo, C.; Cunha-Vaz, J.. "Noninvasive Evaluation of Retinal Leakage Using Optical Coherence Tomography". Ophthalmologica 226 2 (2011): 29-36. http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowAbstract&ArtikelNr=326268&Ausgabe=255172&ProduktNr=224269. Published • 10.1159/000326268 Cachulo, L.; Silva, R.; Fonseca, P.; Pires, I.; Carvajal-Gonzalez, S.; Bernardes, R.; Cunha-Vaz, J.. "Early Markers of Choroidal Neovascularization in the Fellow Eye of Patients with Unilateral Exudative Age-Related Macular Degeneration". Ophthalmologica 225 3 (2011): 144-149. http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowAbstract&ArtikelNr=321064&Ausgabe=254665&ProduktNr=224269. Published • 10.1159/000321064 Cunha-Vaz, J.; Bernardes, R.; Lobo, C.. "Blood-retinal barrier". European Journal of Ophthalmology 21 Suppl. 6 (2011): 3-9. http://www.eur-j-ophthalmol.com/article/blood-retinal-barrier-ejo-d-10-00552. Published • 10.5301/EJO.2010.6049 Bernardes, R.; Serranho, P.; Lobo, C.. "Digital Ocular Fundus Imaging: A Review". Ophthalmologica 226 4 (2011): 161-181. http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowAbstract&ArtikelNr=329597&Ausgabe=255615&ProduktNr=224269. Published • 10.1159/000329597 Silva, R.; Cachulo, L.; Fonseca, P.; Bernardes, R.; Nunes, S.; Vilhena, N.; Faria de Abreu, J.. "Age-Related Macular Degeneration and Risk Factors for the Development of Choroidal Neovascularisation in the Fellow Eye: A 3-Year Follow-Up Study". Ophthalmologica 226 3 (2011): 110-118. http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowFulltext&ArtikelNr=329473&Ausgabe=0&ProduktNr=224269. Published • 10.1159/000329473 Ribeiro, L.; Bernardes, R.; Cunha-Vaz, J.. "Computer-aided Analysis of Fundus Photographs". European Ophthalmic Review 5 2 (2011): 104-107. Open access • Published • 10.17925/EOR.2011.05.02.104 Serranho, P.; Maduro, C.; Santos, T.; Cunha-Vaz, J.; Bernardes, R.. "Synthetic OCT data for image processing performance testing". Proceedings - International Conference on Image Processing, ICIP (2011): 401-404. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856274834&partnerID=MN8TOARS. 10.1109/ICIP.2011.6116534 Nunes, S.; Pereira, I.; Santos, A.; Bernardes, R.; Cunha-Vaz, J.. "Central retinal thickness measured with HD-OCT shows a weak correlation with visual acuity in eyes with CSME". British Journal of Ophthalmology 94 9 (2010): 1201-1204. Published • 10.1136/bjo.2009.165662 Bernardes, R.; Maduro, C.; Serranho, P.; Araújo, A.; Barbeiro, S.; Cunha-Vaz, J.; Bernardes, Rui; et al. "Improved adaptive complex diffusion despeckling filter". Optics Express 18 23 (2010): 24048-24059. http://www.opticsinfobase.org/oe/abstract.cfm?uri=oe-18-23-24048. Published • 10.1364/OE.18.024048 Bernardes, R.; Nunes, S.; Pereira, I.; Torrent-Solans, T.; Rosa, A.; Coelho, D.; Cunha-Vaz, J.. "Computer-Assisted Microaneurysm Turnover in the Early Stages of Diabetic Retinopathy". Ophthalmologica 223 5 (2009): 284-291. http://content.karger.com/ProdukteDB/produkte.asp?Doi=213638. Published • 10.1159/000213638 Nunes, S.; Pires, I.; Rosa, A.; Duarte, L.; Bernardes, R.; Cunha-Vaz, J.. "Microaneurysm Turnover Is a Biomarker for Diabetic Retinopathy Progression to Clinically Significant Macular Edema: Findings for Type 2 Diabetics with Nonproliferative Retinopathy". Ophthalmologica 223 5 (2009): 292-297. http://content.karger.com/ProdukteDB/produkte.asp?doi=213639. Published • 10.1159/000213639 Bernardes, R.; Santos, T.; Cunha-Vaz, J.; Bernardes, Rui; Santos, Torcato; Cunha-Vaz, Jose´. "Increased-Resolution OCT Thickness Mapping of the Human Macula: A Statistically Based Registration". Invest Ophthalmol Vis Sci. 49 5 (2008): 2046-2052. http://www.iovs.org/content/49/5/2046.short. Published • 10.1167/iovs.07-0467 Bernardes, R.; Lobo, C.; Cunha-Vaz, J.. "Multimodal mapping of the macula". Ophthalmology International 3 2 (2008): 58-61. Published Castelo-Branco, M.; Mendes, M.; Sebastião, A.; Reis, A.; Soares, M.; Saraiva, J.; Bernardes, R.; et al. "Visual phenotype in Williams-Beuren syndrome challenges magnocellular theories explaining human neurodevelopmental visual cortical disorders". J Clin Invest. 117 12 (2007): 3720-3729. http://www.jci.org/articles/view/32556/pdf. Published • 10.1172/JCI32556 Nunes, S.; Baptista, P.; Bernardes, R.; Cunha-Vaz, J.. "Comparison of retinal thickness measurements obtained by Retinal Thickness Analyzer (RTA II) and Optical Coherence Tomography (Stratus OCT) in healthy subjects". Exp. Ophthalmol. 32 1 (2006): 13-19. Published Bernardes, R.; Santos, T.; Cunha-Vaz, J.; Rui Bernardes; Torcato Santos; José Cunha-Vaz. "Increased resolution macular thickness mapping by OCT". Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings 1 (2006): 4710-4713. http://www.scopus.com/inward/record.url?eid=2-s2.0-34047106751&partnerID=MN8TOARS. 10.1109/IEMBS.2006.260710 Cunha-Vaz, JG; Bernardes, R.; Cunha-Vaz, José; Bernardes, Rui. "Nonproliferative retinopathy in diabetes type 2. Initial stages and characterization of phenotypes". Progress in Retinal and Eye Research 24 3 (2005): 355-377. http://www.sciencedirect.com/science/article/pii/S1350946204000655. Published • 10.1016/j.preteyeres.2004.07.004 Bernardes, R.; Dias, J.; Cunha-Vaz, J.. "Mapping the Human Blood-Retinal Barrier Function". IEEE Transactions on Biomedical Engineering 52 1 (2005): 106-116. http://ieeexplore.ieee.org/xpl/login.jsp?tp=&arnumber=1369593&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Farnumber%3D1369593. Published • 10.1109/TBME.2004.839801 Lobo CL; Bernardes RC; Figueira JP; de Abreu JR; Cunha-Vaz JG. "Three-year follow-up study of blood-retinal barrier and retinal thickness alterations in patients with type 2 diabetes mellitus and mild nonproliferative diabetic retinopathy.". 122 2 (2004): 211-217. Open access • Published • 10.1001/archopht.122.2.211 Lobo, C.; Faria, P.; Soares, A.; Bernardes, R.; Cunha-Vaz, J.; Lobo, Conceição L.; Faria, Pedro M.; et al. "Macular alterations after small-incision cataract surgery". J Cataract Refract Surg. 30 4 (2004): 752-760. http://www.jcrsjournal.org/article/S0886-3350(03)00582-0/abstract. Published • 10.1016/S0886-3350(03)00582-0 Bernardes, R.; Cunha-Vaz, J.. "Interpretation of Objectively Acquired Retinal Thickness Values—Reply". Arch. Ophthalmol. 121 9 (2003): 1344-1345. http://archopht.ama-assn.org/cgi/content/full/121/9/1344. Published • 10.1001/archopht.121.9.1344 Ludovico, J.; Bernardes, R.; Pires, I.; Figueira, F.; Lobo, C.; Cunha-Vaz, J.; Figueira, J.; et al. "Alterations of retinal capillary blood flow in preclinical retinopathy in subjects with type 2 diabetes". Graefe's Arch Clin Exp Ophthalmol 241 3 (2003): 181-186. http://estudogeral.sib.uc.pt/bitstream/10316/11823/1/Alterations%20of%20retinal%20capillary%20blood%20flow.pdf. Published • 10.1007/s00417-002-0520-9 Hudson, C.; Nrusimhadevara, R.K.; Guan, K.; Gilmore, E.; Flanagan, J.G.; Bernardes, R.; Cunha-Vaz, J.. "Interpretation of objectively acquired retinal thickness values [4] (multiple letters)". Archives of Ophthalmology 121 9 (2003): 1343-1345. http://www.scopus.com/inward/record.url?eid=2-s2.0-17344376226&partnerID=MN8TOARS. 10.1001/archopht.121.9.1343-a Isabel Pires; Rui C Bernardes; Conceição L Lobo; Mário A Soares; José G Cunha-Vaz. "Retinal Thickness in Eyes With Mild Nonproliferative Retinopathy in Patients With Type 2 Diabetes Mellitus: Comparison of Measurements Obtained by Retinal Thickness Analysis and Optical Coherence Tomography". JAMA Ophthalmology (2002): https://app.dimensions.ai/details/publication/pub.1044639455. 10.1001/archopht.120.10.1301 Pires, I.; Bernardes, R.C.; Lobo, C.L.; Soares, M.A.; Cunha-Vaz, J.G.. "Retinal thickness in eyes with mild nonproliferative retinopathy in patients with type 2 diabetes mellitus: Comparison of measurements obtained by retinal thickness analysis and optical coherence tomography". Archives of Ophthalmology 120 10 (2002): 1301-1306. Open access • Published Bernardes, R.; Lobo, C.; Cunha-Vaz, J.. "Multimodal Macula Mapping: A New Approach to Study Diseases of the Macula". Survey of Ophthalmology 47 6 (2002): 580-589. http://www.surveyophthalmol.com/article/S0039-6257(02)00355-7/abstract. Published • 10.1016/S0039-6257(02)00355-7 Cunha-Vaz, JG; Bernardes, R.; Lobo, C.; Faria de Abreu, J.. "Measurements of Retinal Thickness for Evaluation of Macular Edema". Contemporary Ophthalmology 1 25 (2002): 1-6. Published Lobo, C.L.; Bernardes, R.C.; De Abreu, J.R.F.; Cunha-Vaz, J.G.. "One-year follow-up of blood-retinal barrier and retinal thickness alterations in patients with type 2 diabetes mellitus and mild nonproliferative retinopathy". Archives of Ophthalmology 119 10 (2001): 1469-1474. Open access • 10.1001/archopht.119.10.1469 Ludovico, J.; Pires, I.; Bernardes, R.; Lobo, C.; Cunha-Vaz, J.. "Reproducibility of HRF". Exp. Ophtalmol. 27 1-2 (2001): 7-11. Published C L Lobo; R C Bernardes; J G Cunha-Vaz. "Alterations of the Blood-Retinal Barrier and Retinal Thickness in Preclinical Retinopathy in Subjects With Type 2 Diabetes". JAMA Ophthalmology (2000): https://app.dimensions.ai/details/publication/pub.1009294465. 10.1001/archopht.118.10.1364 Lobo, C.L.; Bernardes, R.C.; Cunha-Vaz, J.G.. "Alterations of the blood-retinal barrier and retinal thickness in preclinical retinopathy in subjects with type 2 diabetes". Archives of Ophthalmology 118 10 (2000): 1364-1369. Open access • Published • 10.1001/archopht.118. 10.1364 Lobo, CL; Bernardes, RC; Santos, F.; Cunha-Vaz, JG. "Mapping Retinal Fluorescein Leakage With Confocal Scanning Laser Fluorometry of the Human Vitreous". Archives of Ophthalmology 117 5 (1999): 631-631. Published • 10.1001/archopht.117.5.631 Lobo, C.; Cunha-Vaz, J.; Bernardes, R.. "Retinal leakage analyzer". Int. J. Metabol 2 (1999): 87-88. Published Lobo, C.; Bernardes, R.; De Abreu, J.R.F.; Cunha-Vaz, J.G.; Faria de Abreu, JR; Cunha-Vaz, JG. "Novel imaging techniques for diabetic macular edema". Documenta Ophthalmologica 97 3-4 (1999): 341-347. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033289485&partnerID=MN8TOARS. Published • 10.1023/A:1002479823690
Magazine article	Bernardes, R.; Miguel Morgado; Domingues, JP. "Avaliação do envelhecimento saudável: um exemplo da relação actual entre a engenharia e medicina", Revista da Ordem dos Engenheiros, 2017, http://www.ordemengenheiros.pt/pt/centro-de-informacao/publicacoes/revista-ingenium/revista-ingenium-n-o-152-marco-abril/. Bernardes, R.; Miguel Morgado. "A luz e a oftalmologia", Rua Larga - Universidade de Coimbra, 2015, www.uc.pt/rualarga.
Preprint	Maria Inês Cravo; Rui Bernardes; Miguel Castelo-Branco. "Subtractive adaptation is a more effective and general mechanism in binocular rivalry than divisive adaptation". 2023. https://doi.org/10.1101/2023.01.19.524840. 10.1101/2023.01.19.524840
Thesis / Dissertation	Bernardes, Rui Manuel Dias Cortesão dos Santos. "Desenvolvimento de novas metodologias para o mapeamento multimodal da mácula". PhD, Faculdade de Medicina, Universidade de Coimbra, 2008. http://hdl.handle.net/10316/7508. Bernardes, R.. "A fluorometria confocal por laser do humor vítreo na avaliação do transporte de fluoresceína.". Master, Faculdade de Medicina, Universidade de Coimbra, 2000. Bernardes, R.. "Tacto – aquisição e tratamento de sinais provenientes de sensores piezoeléctricos e programação de microcontroladores.". Degree, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 1992.

Intellectual property

Patent

Bernardes, R.; Castelo-Branco, Miguel; Ambrósio, António Francisco; Silva, Gilberto. 2018. "Method and equipment for central nervous system characterization from retina OCT imaging data.". United States.
Expired
Bernardes, Rui; Miguel Castelo-Branco; Ambrósio, F.; Gilberto Silva. 2017. "Method for the characterization of the healthy status, disease staging, disease progression, disease monitoring and assessment drug and treatment effects of the central nervous system from optical coherence tomography data in humans and animals.". Portugal.
Expired
Bernardes, R.. 2010. "System for analyzing ocular fundus images". United States.
Granted/Issued
Schwartz, A.; Bernardes, R.; Franke, S.; Morgado, A.. 2008. "Method and apparatus for measuring quantity of a fluorochrome in a biological environment.". United States.
Expired

Other

Other output

Benchtop SS-OCT – layout and performance evaluation. Abstract— Optical coherence tomography (OCT) is a non-invasive biomedical imaging technique that provides high speed and high resolution three dimensional and cross sectional images of biological samples, in vivo and in situ. OCT applications targeting small animals is believed to bring developments in medical techniques, instruments, diagnosis and therapies for a number of human diseases as alw. 2017. Domingues, Jose Paulo; Silva, Susana F.; Bernardes, Rui; Morgado, A. M.. http://journals.isel.pt/index.php/i-ETC/article/view/22.
Three-dimensional segmentation and reconstruction of the retinal vasculature from spectral-domain optical coherence tomography. In this work we reconstruct the 3-D shape and location of the retinal vascular network from commercial spectral-domain (SD) optical coherence tomography (OCT) data. The 2-D location of retinal vascular network on the eye fundus is obtained through SVM classification of properly defined fundus images from OCT data,1 taking advantage of the fact that on standard SD-OCT the incident light beam is abs. 2015. Guimarães, Pedro; Rodrigues, Pedro; Celorico, Dirce; Serranho, Pedro; Bernardes, Rui. http://hdl.handle.net/10400.2/3907.
10.1117/1.JBO.20.1.016006
Visual impairment in diabetic patients with and without established blood-retinal barrier leakage and relation with the status of the blood-brain barrier Acta Ophthalmologica. 2014. Quendera, B.; Amorim, A.; Cordeiro, M.; Ferreira, C.; Marques, J.; Bernardes, R.; Reis, A.; Ribeiro, L.; Castelo-Branco, M..
Doctoral Programme: Brain and ocular diseases: How to overcome the barriers? From Basic science to imaging approaches. 2013. Martins, A.; Fernandes, R.; Bernardes, R.. http://www.uc.pt/en/fmuc/phdhs/Courses/translationalresearchinretinaldegenerativediseases.
On the relevance of the 3D retinal vascular network from OCT data. Abnormal patterns of the retinal vascular system have been associated with several heart and cerebral diseases. However, these correlations were obtained using 2D imaging of the eye fundus, disregarding information on the third component (depth) of the vascular system. In this paper, we show that the depth component is relevant and should not be disregarded in this analysis. In this way, the relev. 2013. Serranho, Pedro; Guimarães, Pedro; Rodrigues, P.; Bernardes, Rui. http://hdl.handle.net/10400.2/2717.
Two-dimensional segmentation of the retinal vascular network from optical coherence tomography. The automatic segmentation of the retinal vascular network from ocular fundus images has been performed by several research groups. Although different approaches have been proposed for traditional imaging modalities, only a few have addressed this problem for optical coherence tomography (OCT). Furthermore, these approaches were focused on the optic nerve head region. Compared to color fundus phot. 2013. Rodrigues, Pedro; Guimarães, Pedro; Santos, Torcato; Simão, Sílvia; Miranda, Telmo; Serranho, Pedro; Bernardes, Rui. http://hdl.handle.net/10400.2/3909.
1560-228110.1117/1.JBO.18.12.126011
Explicit and Semi-implicit Complex-Diffusion Schemes for Optical Coherence Tomography Despeckling. In this paper we illustrate and compare the use of explicit and semi-implicit finite difference schemes for nonlinear complex diffusion with different boundary conditions in the context of medical imaging despeckling, namely for Optical Coherence Tomography images of the eye fundus. Performance metrics are shown to illustrate the feasibility and performance of these numerical schemes.. 2013. Rodrigues, Pedro; Guimarães, Pedro; Araújo, Adérito; Barbeiro, Sílvia; Bernardes, Rui; Serranho, Pedro. http://hdl.handle.net/10316/45008.
System for Analyzing Ocular Fundus Images. Software. 2010. Bernardes, R.; Bernardes, Rui.
Image filtering. Software. 2010. Araújo, A.; Serranho, P.; Barbeiro, S.; Bernardes, R.; Santos, T.; Maduro, C.. http://www.mathworks.com/matlabcentral/fileexchange/29801-image-filtering.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2023/10	Machine learning applied to optical coherence tomography data from human and mouse models of disease	(Valencia, Spain)
2022/10	The ageing retina of wild-type and mouse model of alzheimer’s disease	23rd European Association for Vision and Eye Research (Valencia, Spain)
2019/09/28	Optical coherence tomography: a window into the mechanism of neurodegenerative disorders	MEDICON 2019: XV Mediterranean Conference on Medical and Biological Engineering and Computing (Coimbra, Portugal)
2019/09/27	Characterization of the retinal changes of the 3xTg-AD mouse model of Alzheimer’s disease.	MEDICON 2019: XV Mediterranean Conference on Medical and Biological Engineering and Computing (Coimbra, Portugal)
2019/09/27	Sexual dimorphism of the adult human retina assessed by optical coherence tomography	MEDICON 2019: XV Mediterranean Conference on Medical and Biological Engineering and Computing (Coimbra, Portugal)
2018/11	Texture biomarkers of the Alzheimer’s disease: The retina as a window into the brain	CEDOC – Chronic Diseases Research Center, NOVA Medical School. Lisboa (Lisboa, Portugal)
2018/10	Texture biomarkers of Alzheimer’s disease and disease progression in the mouse retina	IEEE BIBE 2018 – The 18th IEEE International Conference on Bioinformatics and Bioengineering IEEE International Conference on Bioinformatics and Bioengineering (Taiwan)
2017	Data Acquisition and Laser Scanning Synchronism in SS-OCT – An Experimental Apparatus	5th Portuguese Meeting in Bioengineering (ENBENG) IEEE-EMBC (Coimbra, Portugal)
2017	Optical Coherence Tomography in Transgenic Mouse Models of Alzheimer's Disease: A Statistical Classification	5th IEEE Portuguese BioEngineering (ENBENG) IEEE-EMBC (Coimbra, Portugal)
2016	Benchtop SS-OCT – layout and performance evaluation	CETC (Portugal)
2015	Maxwell’s equations based 3D model of light scattering in the retina	4th Portuguese Meeting on Bioengineering (ENBENG) IEEE (Porto, Portugal)
2014	Optical properties of the human retina as a window into systemic and brain diseases	ARVO (United States)
2014	Modeling the topography of the healthy human retina	ISIE (United States)
2014	Monte Carlo simulation of diabetic macular edema changes on optical coherence tomography	ARVO (United States)
2014	Simulation of DME changes on OCT	EVER (France)
2014	Different genetic polymorphisms are associated with different phenotypes on non-proliferative diabetic retinopathy	ARVO (United States)
2014	Visual impairment in diabetic patients with and without established blood-retinal barrier leakage and relation with the status of the blood-brain barrier	EVER (France)
2014	Occluded and partially occluded blood vessel detection from macular OCT scans	ARVO (United States)
2014	Retinal vascular network in 3D from optical coherence tomography data	ECMI (Italy)
2014	Automatic identification of eyes at risk of developing idiopathic macular hole	EVER (France)
2014	Preclinical identification of eyes at risk of developing idiopathic macular hole – an update	ARVO (United States)
2013/02	Blood-retinal barrier function: Noninvasive assessment	Beating the Blood-Brain and Other Blood Barriers University of Lisbon (Lisboa, Portugal)
2013	Blood-retinal barrier function: noninvasive assessment	Beating the Blood-Brain and Other Blood Barriers School of Medicine, Institute of Molecular Medicine, Portugal (Lisbon, Portugal)
2013	3D Reconstruction of the Retinal Vascular Network Morphology from Optical Coherence Tomography	3rd Portuguese Bioengineering Meeting IEEE Engineering in Medicine and Biology Society Portuguese Chapter (Braga, Portugal)
2013	Improved 3D Retinal Vascular Tree Segmentation	3rd Portuguese Bioengineering Meeting IEEE Engineering in Medicine and Biology Society Portuguese Chapter (Braga, Portugal)
2013	Non-invasive discrimination between perfused and occluded vessels by optical coherence tomography	EVER 2013 European Association for Vision and Eye Research (Nice, France)
2013	Enhanced 3D retinal vascular network reconstruction from high-definition SD-OCT.	EVER 2013 European Association for Vision and Eye Research (Nice, France)
2013	Fast fully-automated multimodal image co-registration (optical coherence tomography, colour fundus photography, red-free, fluorescein angiography).	EVER 2013 European Association for Vision and Eye Research (Nice, France)
2013	Development of an Optical Coherence Tomograph for Small Animal Retinal Imaging	XIII Mediterranean Conference on Medical and Biological Engineering and Computing 2013 International Federation for Medical and Biological Engineering (IFMBE) (Sevilla, Spain)
2013	Fully-Automatic Multimodal Co-Registration of Retinal Fundus Images.	The International Conference on Health Informatics (ICHI) 2013 International Federation of Medical and Biological Engineering (IFMBE) (Vilamoura, Portugal)
2012/10	3D vascular network of the human macula from optical coherence tomography	RITA – Retinal Imaging Treatment and Analysis meeting Quinze-Vingts & Institut de la Vision (Paris, France)
2012	3D Vascular Network of the Human Macula From Optical Coherence Tomography	Retinal Imaging Treatment and Analysis meeting (RITA) 2012 Vision Institute (Paris, France)
2012	Optical Coherence Tomography: signal signature on neuronal ageing and blood-retinal barrier status	EVER 2012 EVER - European Association for Vision and Eye Research (Nice, France)
2012	3D Nonlinear Complex-Diffusion Filter on GPU	34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) IEEE Engineering in Medicine and Biology Society (EMBC) (San Diego, California, USA, United States)
2012	Identification of Eyes at Risk of Developing Idiopathic Macular Holes by Support Vector Machines	2nd Portuguese BioEngineering Meeting Portuguese Chapter of IEEE-EMBS (Coimbra, Portugal)
2012	Vascular Network of the Human Macula from OCT	Ciclo de Diulgação AIBILI/CNTM AIBILI (Coimbra, Portugal)
2012	3D Blood Vessels Segmentation from Optical Coherence Tomography	Ciclo de Divulgação AIBILI/CNTM AIBILI (Coimbra, Portugal)
2012	Vascular Network of the Human Macula from OCT	EVER 2012 European Association for Vision and Eye Research (Nice, France)
2012	3D Vascular Network of the Ocular Fundus from SD-OCT	4th Annual Meeting of IBILI IBILI (Coimbra , Portugal)
2012	3D Blood Vessels Segmentation from Optical Coherence Tomography	EVER 2012 European Association for Vision and Eye Research (Nice, France)
2012	3D Retinal Vascular Network From Optical Coherence Tomography Data	ICIAR 2012 International Conference on Image Analysis and Recognition (Aveiro, Portugal)
2011/01	A imagem na visão: Do pixel à função	Seminário de Bioengenharia Escola Superior de Tecnologia e Gestão do Instituto Politécnico de Portalegre (Portalegre, Portugal)
2011	A imagem na visão: do pixel à função	II Seminário de Bioengenharia ESTG Escola Superior de Tecnologia e Gestão (Portalegre, Portugal)
2011	Imaging New Developments	Programa Doutoral “Translational Research in Retinal Degenerative Diseases” IBILI/FMUC (Coimbra, Portugal)
2011	New approach for DME imaging using OCT	11th EURETINA Congress EURETINA (London, United Kingdom)
2011	Ocular Fundus Imaging: From Structure to Function	1 Encontro Nacional de Bioengenharia Capítulo Português do EMBS, IEEE (Oeiras, Portugal)
2010/04	Modified adaptive anisotropic complex diffusion despeckling filter	Instituto de Sistemas e Robótica, Departamento de Engenharia Electrotécnica e de Computadores, Universidade de Coimbra (Coimbra, Portugal)
2010	Imaging the Retina: From Pixel to Function. Programa Doutoral “Translational Research”	IBILI/FMUC (Coimbra, Portugal, Portugal)
2010	OCT for monitoring retinal leakage	10th EURETINA Congress EURETINA (Paris, France)
2010	Modified Adaptive Anisotropic Complex Diffusion Despeckling Filter.	(Coimbra, Portugal)
2010	Filtros Complexos na Tomografia de Coerência Óptica	Ciclo de Divulgação AIBILI: Novas Tecnologias em Imagem Médica AIBILI (Coimbra, Portugal)
2010	Optical Coherence Tomography speckle denoising	EVER 2010 European Association for Vision and Eye Research (EVER) (Heraklion, Greece)
2010	Correlation between Retinal and Cortical thickness	2nd Annual Meeting of IBILI IBILI (Coimbra, Portugal)
2010	OCT noise despeckling using a 3D nonlinear complex diffusion filter	6th International Conference on Technology and Medical Science TMSi (Porto, Portugal)
2010	Noninvasive Assessment of Blood-Retinal Barrier Function by High-Definition Optical Coherence Tomography	6th International Conference on Technology and Medical Science TMSi (Porto, Portugal)
2010	OCT Noise Despeckling by 3D Complex Diffusion Filtering	ISMA - Workshop on Imaging Sciences and Medical Applications DM-FCTUC, University of Coimbra (Coimbra, Portugal)
2010	Line Integral Images from HD-OCT Three Dimensional Data Sets	ISMA - Workshop on Imaging Sciences and Medical Applications DM-FCTUC, University of Coimbra (Coimbra, Portugal)
2009/05	Retmarker. Identifying progression on fundus images	9th EURETINA Congress EURETINA (Nice, France)
2009/05	RetMarker. Identifying progression on fundus images	EURETINA – 9th European Society of Retina Specialists Congress EURETINA – 9th European Society of Retina Specialists Congress (Nice, France)
2009	High-definition fourier domain OCT: non-invsive assssment of BRB changes	EVER 2009 EVER - European Association for Vision and Eye Research (Portoroz, Slovenia)
2009	Biomarkers of progression of retinal disease	9th EURETINA Congress Euretina (Nice, France)
2009	Imaging the Retina: From Pixel Function	1st IBILI Annual Meeting 2009 IBILI (Coimbra, Portugal)
2009	Imagiologia Funcional com OCT	Ciclo de Divulgação AIBILI/IBILI - Desenvolvimento de Productos em oftalmologia AIBILI (Coimbra, Portugal)
2009	Semi-automated assessment of microaneurysm formation rate from color fundus photographs in patients with mild NPDR	EVER 2009 Congress EVER - European Association for Vision and Eye Research (Portoroz, Slovenia)
2009	Evaluation of Blood-retinal barrier function from fourier domain high-definition Optical Coherence Tomography	11th World Congress 2009 - IFMBE Conference The World Congress on Medical Physics and Biomedical Engineering - IUPESM (Munich, Germany)
2009	Validation of a predictive model for diabetic retinopathy progression in type-2 diabetic patients with mild nonproliferative diabetic retinopathy.	EVER 2009 EVER - European Association for Vision and Eye Research (Portoroz, Slovenia)
2009	A New Method For Semi-automated Measurement Of Microaneurysms Formation Rate From Color Fundus Photographs In Diabetic Retinopathy	9th EURETINA Congress EURETINA (Nice, France)
2009	Alteration of the blood-retinal barrier identified by retinal leakage analysis is a predictor for conversion to wet age-related macular degeneration	ARVO 2009 Annual Meeting The Association for Research in Vision and Ophthalmology, Inc. (ARVO) (Fort Lauderdale, FL, United States)
2008/09	Diabetic macular edema correlation increased macula thickness/VA loss	2nd European OCT meeting: Advances in spectral domain OCT (Paris, France)
2008/09	Increased retinal thickness and FA leakage	2nd European OCT meeting: Advances in spectral domain OCT (Paris, France)
2008/06	Imaging the eye fundus	1st Workshop on Optics and Vision, School of Medicine, University of Crete (Creta, Greece)
2008	Retinal Thickness vs. Retinal Sensitivity at the Central Human Macula	2008 ARVO/ISIE Imaging Conference The Association for Research in Vision and Ophthalmology, Inc. (ARVO) (Fort Lauderdale, FL, United States)
2008	Perspectives for multimodal imaging of the retina in disease	8th Euretina Congress EURETINA (Vienna, Austria)
2008	Imaging the Eye Fundus	Postgraduate Course in "Optics and Vision", 1st Workshop on Optics and Vision Universidade de Creta (Crete, Greece)
2008	Diabetic Macular Edema Correlation Increased Macula Thickness/VA loss	2nd European OCT meeting: Advances in spectral domain OCT Carl Zeiss Meditec France (Paris, France)
2008	Increased Retinal Thickness and FA Leakage	2nd European OCT meeting: Advances in spectral domain OCT Carl Zeiss Meditec France (Paris, France)
2008	New Developments in OCT Evaluations	EVER/SIS EVER (Portoroz, Slovenia)
2008	Instrumentation Adaptation for Quantitative Fluorescein Angiograms	Ciclo Divulgação AIBILI AIBILI (Coimbra, Portugal)
2008	Increased Retinal Thickness and FA Leakage	EVER 2008 Congress European Association for Vision and Eye Research (Portoroz, Slovenia)
2008	Retinal Leakage Analysis	Jornadas Internacionais de Oftalmologia Centro de Ciências da Visão (serviço de Oftlmologia dos HUC) (Coimbra, Portugal)
2008	Risk Markers for Progression to CSME in Patients with Mild Nonproliferative Retinopathy in Diabetes Type 2	EVER 2008 Congress European Association for Vision and Eye Research (Portoroz, Slovenia)
2007	Instrumentation adaptation for quantative fluorescein aniograms	2007 EVER/SIS European Association for Vision and Eye Research (Portoroz, Slovenia)
2007	Novas Técnicas de Imagem do Fundo Ocular	XVII Jornadas Internacionais de Oftalmologia Hospitais da Universidade de Coimbra (Coimbra, Portugal)
2007	Instrumentation Adaptation for Quantitative Fluorescein Angiograms	Dia do Centro de Oftalmologia IBILI (Coimbra, Portugal)
2007	Quantificação de Fluorescência	Ciclo de Divulgação AIBILI (Coimbra, Portugal)
2007	Quantitative Fluorescein Angiograms	EVER 2007 Congress European Association for Vision and Eye Research (Portoroz, Slovenia)
2007	The Sensitivity of the OCT in the Diagnosis of Clinically Significant Macular Edema	EVER 2007 Congress EVER - European Association for Vision and Eye Research (Portoroz, Slovenia)
2006/05	Retinal leakage analysis	EURETINA – 6th European Society of Retina Specialists Congress (Lisboa, Portugal)
2006	Establishment of a Retinal Thickness Atlas (RT-Atlas)	EVER 2006 Congress European Association for Vision and Eye Research (Vilamoura, Portugal)
2006	Increased Resolution OCT Mapping	28th Annual International Conference of the IEEE Engineering Medicine and Biology Society (EMBS) IEEE Engineering in Medicine and Biology Society (EMBS) (New York City, NY, United States)
2006	Directions for Imaging Development	XVI Jornadas Internacionais de Oftalmologia Centro de Ciências da Visão (Coimbra, Portugal)
2006	Retinal Leakage Analysis	6th EURETINA Congress EURETINA (Lisboa, Portugal)
2006	Establishment of a retinal thickness atlas	2006 ARVO/ISIE Imaging Conference The Association for Research in Vision and Ophthalmology, Inc. (ARVO) (Fort Lauderdale, FL, United States)
2006	Carl Zeiss Meditec Meeting	AIBILI/ Carl Zeiss Meditec Meeting AIBILI (Coimbra, Portugal)
2006	Multimodal Macula Mapping by Deformable Image Registration	CompIMAGE Centro Internacional de Matemática (Coimbra, Portugal)
2006	Increased OCT Mapping Resolution by Merging Line and Circle Scan-Types	EVER 2006 Congress European Association for Vision and Eye Research (Vilamoura, Portugal)
2006	Identification of different phenotypes of nonproliferative retinopathy of diabetes type 2 using cluster and discriminant analysis	Ever 2006 Congress European Association for Vision and Eye Research (Vilamoura, Portugal)
2006	Establishment of a normative database by registration of RTA maps into the RT-Atlas	EVER 2006 Congress European Association for Vision and Eye Research (Vilamoura, Portugal)
2005/12	Novas tecnologias de imagem médica – A imagem no diagnóstico das alterações da retina	ISEC – Instituto Superior de Engenharia de Coimbra (Coimbra, Portugal)
2005	Functional and morphological retinal data fusion	EVER/SIS 2005 European Association for Vision and Eye Research (Vilamoura, Portugal)
2005	Novas Tecnologias de Imagem Médica – A Imagem no diagnóstico das alterações da retina	Workshop "Visão Artificial" ISEC, Instituto Superior de Engenharia de Coimbra (Coimbra, Portugal)
2005	Comparison between retinal edema by color fundus photography and retinal thickness maps	Dia do Centro de Oftalmologia / V Jornadas Internacionais de Oftalmologia IBILI (Coimbra, Portugal)
2005	Registration of functional and morphological imaging modalities	15th meeting of the EASD Eye Complications Study Group (EASDec) AIBILI (Coimbra, Portugal)
2005	Imagem Multimodal, Aplicações	Ciclo de Divulgação AIBILI / IBILI AIBILI (Coimbra, Portugal)
2005	Distortion free registration between multifocal ERG and retinal leakage analyzer	3rd European Medical and Biological Engineering Conference EMBEC'05 European Medical and Biological Engineering Conference (EMBEC) (Prgaue, Czech Republic)
2005	Earmarking retinal changes in a sequence of digital color fundus photographs	3rd European Medical and Biological Engineering Conference EMBEC'05 European Medical and Biological Engineering Conference (EMBEC) (Prague, Czech Republic)
2005	Functional and morphological retinal data fusion	3rd European Medical and Biological Engineering Conference EMBEC'05 European Medical and Biological Engineering Conference (EMBEC) (Prague, Czech Republic)
2005	Increased Resolution OCT Mapping	EVIGeM The European Virtual Institute of Geometric and Dimensional Metrology (Bilbau, Spain)
2005	Implementing a Colour-Coded scheme for Earmarking retinal changes in a sequence of digital color fundus photographs	Ever 2005 Congress European Association for Vision and Eye Research (Vilamoura, Portugal)
2005	Multimodal macula mapping: study for rigid, perspective and deformable image registration	EVER 2005 Congress European Association for Vision and Eye Research (Vilamoura, Portugal)
2005	Optical Coherence Tomography and Multimodal Mapping	EVI-Genoret - Harmonization Workshop The European Vision Institute (Coimbra, Portugal)
2005	Earmarking retinal changes in a sequence of digital color fundus photographs	15th meeting of the EASD Eye Complications Study Group (EASDec) AIBILI (Coimbra, Portugal)
2005	Automatic Establishment of Macular Coordinates	15th meeting of the EASD Eye Complications Study Group (EASDec) AIBILI (Coimbra, Portugal)
2005	Registration of functional and morphological imaging modalities	ISIE – 3rd Annual Meeting ARVO-ISIE/Imaging (Fort Lauderdale, FL, United States)
2005	Retinal thickness measurements. RTA II vs. Stratus OCT in Healthy Subjects	ISIE – 3rd Annual Meeting ARVO-ISIE/Imaging (Fort Lauderdale, FL, United States)
2005	Imagiologia da degenerescência macular	Ciclo de Divulgação AIBILI / IBILI AIBILI (Coimbra, Portugal)
2003/09	Imaging Processing – Soft Computing in Medicine	EUNITE Summer School on Intelligent Techniques for Medical Applications (Coimbra, Portugal)
2003	RLA - Retinal leakage analyzer	ARVO/SIG ARVO/SIG (Fort Lauderdale, United States)
2003	Imaging Processing - Soft Computing in Medicine	Eunite Summer School Faculdade de Ciências e Tecnologia - Universidade de Coimbra (Coimbra, Portugal)
2003	Retinal Thickness Mapping: problems and solutions	EVER/SIS EVER (Alicante, Spain)

Supervision

	Thesis Title Role	Degree Subject (Type) Institution / Organization
2023/10 - Current	New insights in middle ear anatomy: contribution of optical coherence tomography (OCT) in identification and characterization of structures and components Co-supervisor
2023/09 - Current	Searching for the interocular neurovascular link Supervisor
2023/01 - Current	Searching for a neurovascular coupling reflex pathway Supervisor	Doctorate in Physics Engineering (PhD) Universidade de Coimbra Centro de Imagem Biomédica e Investigação Translacional, Portugal
2021/09 - Current	Development of phase-sensitive optical coherence elastography with ultrasound impulses for ophthalmological imaging Supervisor
2020/10 - Current	Texture analysis of Optical Coherence Tomography retinal images as a novel and early predictor of diabetic retinopathy onset and progression Co-supervisor	Doctoral Programme in Health Sciences (PhD) Universidade de Coimbra Faculdade de Medicina, Portugal
2020/10 - Current	Texture analysis of Optical Coherence Tomography retinal images as a novel and early predictor of diabetic retinopathy onset and progression Co-supervisor	Faculdade de Medicina, Universidade de Coimbra, Portugal
2020/09 - Current	Imaging the Mechanical Properties of the Retina of Small Animals by Optical Coherence Tomography Elastography Co-supervisor	Doctorate in Biomedical Engineering (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2020/04 - Current	Neuronal Inhibition and Noise in Perceptual Decision-Making: A Computational Approach Co-supervisor	Doctorate in Biomedical Engineering (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019/07 - Current	Exploring texture biomarkers of neurodegeneration in the retina Supervisor	Doctorate in Biomedical Engineering (PhD) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2022/10 - 2023/09	Automatic segmentation of retinal layers in optical coherence tomography images: a flexible model for multiple animal models of disease and acquisition systems Supervisor
2019/12/01 - 2022/11	Non-invasive optical coherence tomography towards the imaging of the neurodegenerative disease: from the animal retina to the human brain Supervisor	Instituto das Ciências Nucleares Aplicadas à Saúde, Portugal Coimbra Institute for Biomedical Imaging and Translational Research, Portugal
2020/03 - 2022/01	Técnicas de análise de textura para processamento de imagem Co-supervisor	Master in Statistics, Mathematics and Computation (Master) Universidade Aberta, Portugal
2020/09 - 2021/09	Identification of changes in retinal images of animal models of Alzheimer’s disease using a deep learning approach Supervisor	Master in Biomedical Engineering (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019/09 - 2020/11	Age Estimation of the Central Nervous System from Retinal Images Supervisor	Engenharia Biomédica (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2018/10 - 2020/07/22	Aplicação de Máquinas de Vector Suporte para classificação de ratos transgénicos através de imagem da retina Co-supervisor	Estatística, Matemática e Computação (Master) Universidade Aberta, Portugal
2018/09 - 2019/07	Exploring texture biomarkers of neurodegeneration in the retina Supervisor	Engenharia Biomédica (Other) Universidade de Coimbra, Portugal
2016/09 - 2017/09/25	Development of an image captation system using simple reflectivity and scanning control improvements in SS-OCT Co-supervisor	Engenharia Física (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015/09 - 2016/09	Swept Source OCT for retinal imaging on small animals: Performance, phase stabilization and optical setup Co-supervisor	Engenharia Física (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015/09 - 2016/09	High speed data acquisition for Swept-Source OCT. Co-supervisor	Engenharia Física (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015/04/02 - 2016/04/30	Science Management [Post-doc fellowship: SFRH/BPD/105616/2015] Supervisor	Fundação para a Ciência e a Tecnologia, Portugal
2015/04 - 2016/04	Science Management [Postdoc fellowship: SFRH/BGCT/52191/2013] Supervisor	Fundação para a Ciência e a Tecnologia, Portugal
2011/09 - 2012/09	Retinal Vascular Network from Color Fundus Photography: A SVM Classification Approach Co-supervisor	Engenharia Biomédica (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2010/09 - 2011/07	Processos de segmentação e reconhecimento de padrões em imagiologia da retina e cérebro / Segmentation pattern recognition processes in retina and brain imaging Co-supervisor	Engenharia Biomédica (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2006/09 - 2007/09	Retinal Tracking Co-supervisor	Engenharia Biomédica (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2006/09 - 2007/09	Sistema para Calibração de disparo de Lazer através de Lâmpada de Fenda Co-supervisor	Engenharia Biomédica (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2003/09 - 2006/07	Cluster analysis and pattern identification at the initial stages of diabetic retinopathy Co-supervisor	Ciências da Visão (Master) Faculdade de Medicina, Universidade de Coimbra, Portugal Associação para Investigação Biomédica e Inovação em Luz e Imagem, Portugal
2004/09 - 2005/09	Aquisição e manipulação de imagens a partir de uma lâmpada de fenda Supervisor	Engenharia Informática (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2003/09 - 2004/09	OFTAL-SEGMENT - Segmentação de imagens de interferometria óptica da retina humana Co-supervisor	Engenharia Electrotécnica (Degree) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2002/09 - 2003/09	Cálculo do derrame de fluoresceína da circulação sanguínea para o vítreo do olho humano. Co-supervisor	Engenharia Electrotécnica (Degree) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2001/09 - 2002/09	Implementação de um Sistema de Controlo e Gestão de Informação de um Centro de Ensaios Clínicos baseado numa Internet Supervisor	Engenharia Informática e de Sistemas (Degree) Instituto Politécnico de Coimbra Instituto Superior de Engenharia de Coimbra, Portugal
2001/09 - 2002/09	Sistemas de Aquisição de dados em Aplicações Biomédicas Supervisor	Engenharia Electrotécnica (Degree) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Event organisation

	Event name Type of event (Role)	Institution / Organization
2023/10/26 - 2023/10/26	Course - Basic principles of state-of-the-art ophthalmic instrumentation - Part II - Machine learning aspects and applications @ EVER - European Association for Vision and Eye Research (2023/10/26 - 2023/10/26) Workshop (Co-organisor)
2023/10/26 - 2023/10/26	Course - Basic principles of state-of-the-art ophthalmic instrumentation - Part I - Optical concepts @ EVER - European Association for Vision and Eye Research (2023/10/26) Seminar (Co-organisor)
2022/10 - 2022/10	Course - Basic principles of state-of-the-art ophthalmic instrumentation @ EVER - European Association for Vision and Eye Research (2022/10) Symposium (Co-organisor)
2022/04 - 2022/04	Special Session - Developments in Imaging for Ocular and Neurodegenerative Disorders (Imaging4OND) (2022/04 - 2022/04) Symposium (President of the Organising Committee)
2022/02/23 - 2022/02/23	Special Session - The Retina as a Window into the Brain (2022/02/23 - 2022/02/23) Workshop (Co-organisor)	European Association for Vision and Eye Research, France
2019/10 - 2019/10	Course - Basic principles of state-of-the-art ophthalmic instrumentation @ EVER - European Association for Vision and Eye Research (2019/10 - 2019/10) Workshop (Co-organisor)	European Association for Vision and Eye Research, France
2019/09 - 2019/09	Special Session - Ocular Imaging (2019/09 - 2019/09) Symposium	MEDICON – 15th Mediterranean Conference on Medical and Biological Engineering and Computing, Portugal
2018/10/04 - 2018/10/06	Course - Basic principles of state-of-the-art ophthalmic instrumentation @ EVER - European Association for Vision and Eye Research (2018/10/04 - 2018/10/04) Workshop (Co-organisor)	European Association for Vision and Eye Research, Belgium
2017/09/27 - 2017/09/30	Course - Basic principles of state-of-the-art ophthalmic instrumentation @ EVER - European Association for Vision and Eye Research (2017/09/27 - 2017/09/27) Workshop (Co-organisor)	European Association for Vision and Eye Research, Belgium
2016 - 2017	5th Portuguese Bioengineering Meeting (2017/02/16 - 2017/02/18) Meeting (Co-organisor)	IEEE Portugal EMBS Chapter, Portugal
2016 - 2016	Mathematical methods in biology. (Mathematics of Complex Systems: from precision medicine to smart cities) Symposium (Other)
2015 - 2015	VII Annual Meeting of IBILI Meeting (Other)
2014 - 2014	VI Annual Meeting of IBILI Meeting (Other)
2013 - 2013	V Annual Meeting of IBILI Meeting (Other)	CNC.IBILI, Portugal
2012 - 2013	3rd Portuguese Bioengineering Meeting (2013/02/20 - 2013/02/22) Meeting (Member of the Organising Committee)	IEEE Portugal EMBS Chapter, Portugal
2012 - 2012	IV Annual Meeting of IBILI Meeting (Other)
2011 - 2012	2nd Portuguese Bioengineering Meeting (2012/02/23 - 2012/02/25) Meeting (Co-organisor)	IEEE Portugal EMBS Chapter, Portugal
2010/03/01 - 2011/03/04	1st Portuguese Bioengineering Meeting (2011/03/01 - 2011/03/04) Meeting (Member of the Organising Committee)	IEEE Portugal EMBS Chapter, Portugal
2011 - 2011	III Annual Meeting of IBILI Meeting (Other)
2010 - 2010	II Annual Meeting of IBILI Meeting (Other)
2009/05/14 - 2009/05/17	Session: Development of the OCT technology and its application @ EURETINA - European Society of Retina Specialists Congress (2009/05/14 - 2009/05/17) Other (Other)
2009 - 2009	I Annual Meeting of IBILI Meeting (Other)
2007/10/05 - 2007/10/05	EVER/SIS - European Association for Vision and Eye Research/Special Interest Symposium - Retinal image analysis and quantitative fluorescein angiograms - Support: Pfizer (2007/10/05 - 2007/10/05) Symposium (President of the Organising Committee)	European Association for Vision and Eye Research, Belgium
2005/10/06 - 2005/10/06	EVER/SIS - European Association for Vision and Eye Research/Special Interest Symposium - Functional imaging of the retina. - Support: Heidelberg Engineering. (2005/10/06 - 2005/10/06) Symposium (President of the Organising Committee)	European Association for Vision and Eye Research, Belgium
2003/10/10 - 2003/10/10	EVER/SIS - European Association for Vision and Eye Research/Special Interest Symposium - Macula Imaging. - Support: Heidelberg Engineering. (2003/10/10 - 2003/10/10) Symposium (President of the Organising Committee)	European Association for Vision and Eye Research, Belgium

Jury of academic degree

	Topic Role	Candidate name (Type of degree) Institution / Organization
2022/12/02	Automatic Analysis of Retinal Images to Aid in the Diagnosis and Grading of Diabetic Retinopathy (Thesis) Main arguer	Roberto Romero Oraá (PhD) Universidad de Valladolid, Spain
2022/09/28	Quantitative evaluation of collagen fiber organization from SHG images President of the jury	Maria Alves Mateus (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2022/04/19	Development of tools within a Graphical User Interface for the automatic longitudinal analysis of Dry Age-related Macular Degeneration (Thesis) Main arguer	Gustavo Sousa Brites (Master) Universidade de Lisboa Faculdade de Ciências, Portugal
2021/09/30	Identification of changes in retinal images of animal models of Alzheimer’s disease using a deep learning approach Supervisor	Rita Caetano Trindade (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2021/09/28	Glaucoma Prediction Based on 3D-OCT Speckle Imaging (Thesis) Main arguer	Vânia Sofia Bastos Silva (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2021/05/12	Diabetic Retinopathy Grading in Color Eye Fundus Images (Thesis) Arguer	Teresa Manuel Sá Finisterra Araújo (PhD) Universidade do Porto Faculdade de Engenharia, Portugal
2020/11/13	Age Estimation of the Central Nervous System from Retinal Images Supervisor	Érica Maria Vicente Prioste (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019/07/22	Exploring texture biomarkers of neurodegeneration in the retina Supervisor	Ana Teresa Casimiro Nunes (Other) Universidade de Coimbra, Portugal
2019/02/19	Cognitive and autonomic neural manifestations captured using wearable sensors for reliable software development. President of the jury	Gonçalo Daniel Tavares Duarte (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2018/09/28	Battery-free sensor with wireless capabilities for soft and biocompatible monitoring. President of the jury	Bruno da Silva de Oliveira (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2018/07/23	SWORD Zephyr: Effort monitoring in Pulmonary Rehabilitation. (Thesis) Main arguer	Daniela da Costa Santos (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017/09/25	Development of an image acquisition system using simple reflectivity and scanning control improvements in SS-OCT. Supervisor	Andoni Calvo y Santos (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017/03/27	Development of techniques for haptic exploration and recognition of objects: a contribution to autonomous robotic hands (Thesis) Arguer	Ricardo Filipe Alves Martins (PhD) Universidade de Coimbra, Portugal
2016/09/29	Vitreoretinal interface pathology: modelling and prediction. (Thesis) Main arguer	José Vargas Galveias (Other) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2016/09/22	Automatic reconstruction of the retina capillary network using blood flow models. (Thesis) Main arguer	Rute Filipa Dias Marto (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2016/03/30	Optical Coherence Tomography: Layout Simulation Using MATLAB. (Thesis) Arguer	Patrícia Miguel da Silva Carvalho (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015/09/22	Microglia as cellular targets for immunomodulation during neurodevelopment. President of the jury	Sónia Raquel Nunes Henriques (Master) Universidade de Coimbra Faculdade de Medicina, Portugal
2015/09/22	The role of EEG as a biomarker tool in assessing plastic changes induced by transcranial magnetic stimulation in stroke patients. President of the jury	Rita Barbosa Sousa Gouveia (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015/09/22	Swept Source Optical Coherence Tomography for Small Animals - Performance Parameters and Optic Modelling. (Thesis) Arguer	André Filipe Lopes Pedrosa (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015/05/15	Advanced Image Analysis for the Assessment of Retinal Vascular Changes (Thesis) Arguer	Behdad Dasht Bozorg (PhD) Universidade do Porto Faculdade de Engenharia, Portugal
2014/09/18	Hemodynamic parameters extraction using laser speckle effect. (Thesis) Main arguer	Diana Filipa Sousa Capela (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013/09/17	Swept Source Optical Coherence Tomography for Small Animals Imaging: System Control and Data Acquisition (Thesis) Main arguer	José Adriano de almeida Agnelo (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013/09/17	Software for clinical data interaction (Thesis) Main arguer	Pedro Gabriel Ferreira Gonçalves (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013/09/16	Segmentação 3D do fígado em exames de TEP e TAC (Thesis) Main arguer	Diana Sofia Xavier Mendes (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012/09/21	Lung segmentation in PET and CT exams (Thesis) Arguer	Fábio Rui Alves Nery (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2012/09/20	Retinal vascular network from color fundus photography: a SVM classification approach Supervisor	Rui Miguel Morgado Venâncio (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2011/09/14	Development of co-registration techniques for comparison of whole-body PET/CT studies. (Thesis) Arguer	André Filipe Cidra Rocha Libório (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2011/07/12	Segmentation processes and pattern recognition in retinal and brain imaging Supervisor	Pedro Guimarães Sá Correia (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2010/07/26	Structural and structure-function correlations in neurodevelopmental and aging disorders of the visual system (Thesis) Main arguer	Frederico Ramiro Santos Lourenço (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2009/09/21	Reconstrução de Imagem PET por Decomposição do Sinograma (Thesis) Arguer	Hugo Alberto da Mota Martins Lages Fernandes (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008/09/08	BW-Eye: Ophthalmological Decision Support System based on Clinical Workflow and Data Mining Techniques – Image Registration Algorithm (Thesis) Arguer	Ricardo Filipe Alves Martins (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008/07/22	BW-Eye: Ophthalmolgical Decision Support System based on Clinical Workflow and Data Mining Techniques – Angiography Equipment Integration & Creation of thickness maps using OCT images (Thesis) Arguer	Liliana Jacinta Simões Ferraz (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007/09	Retinal Tracking Supervisor	Ivânia Margarida Magalhães Pereira (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2007/09	Sistema para Calibração de disparo de Laser através de Lâmpada de Fenda Supervisor	Lionel Monteiro Morgado (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2006/07	Cluster analysis and pattern identification at the initial stages of diabetic retinopathy Supervisor	Sandrina Gonçalves Nunes (Master) Universidade de Coimbra Faculdade de Medicina, Portugal
2005/09	Aquisição e manipulação de imagens a partir de uma lâmpada de fenda Supervisor	Carlos Miguel Ribeiro & Luís Miguel Lima (Master) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2004/09	OFTAL-SEGMENT – Segmentação de imagens de interferometria óptica da retina humana Supervisor	César Miguel Rodrigues Lourenço & João Carlos Pais Baptista (Other) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2003/09	Cálculo do derrame de fluoresceína da circulação sanguínea para o vítreo do olho humano Supervisor	Bruno Miguel Aires Oliveira & Celso Gonçalo Serrano de Almeida (Other) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2002/09	Sistemas de Aquisição de dados em Aplicações Biomédicas Supervisor	Nuno Jorge Gonçalves (Other) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2002/09	Implementação de um Sistema de Controlo e Gestão de Informação de um Centro de Ensaios Clínicos baseado numa Internet. Supervisor	Pedro Samuel Santos Figueiredo Sousa (Other) Instituto Politécnico de Coimbra Instituto Superior de Engenharia de Coimbra, Portugal

Association member

	Society Organization name	Role
2014/06 - Current	IEEE - Institute of Electrical and Electronics Engineers	Senior Member
2010/04 - Current	IEEE Portugal EMBS Chapter	Member
1999 - Current	EVER - European Association for Vision and Eye Research	Member
2000 - 2014/06	IEEE - Institute of Electrical and Electronics Engineers	Member
2005 - 2014	EVI - European Vision Institute	Member
2003 - 2014	ISIE - International Society for Imaging in the Eye	Member
1998 - 2014	ARVO - Association for Research in Vision and Ophthalmology	Member

Committee member

	Activity description Role	Institution / Organization
2021/07 - Current	Associate Editor: Frontiers in Cellular Neuroscience Member
2013/10 - Current	Editorial Board Member: Applied Scientific Reports Member
2010/01 - Current	Editorial Board Member: Ophthalmologica Member
2022 - 2022	Program Committee IMPROVE 2022: International Conference on Image Processing and Vision Engineering Member
2021 - 2021	Program Committee IMPROVE 2021: International Conference on Image Processing and Vision Engineering Member
2021 - 2021	Program Committee CSA 2021: International Conference on Computer Science and Applications Member
2020 - 2020	Program Committee ICIAR 2020: International Conference on Image Analysis and Recognition Member
2019 - 2019	Program Committee MEDICON 2019: Med. Conf. on Medical and Biological Engineering and Computing Member
2019 - 2019	Scientific Committee ENBENG 2019: IEEE 6th Portuguese Meeting on Bioengineering Member
2019 - 2019	Scientific Committee Challenges in Healthcare 2019: Challenges in Healthcare ¿ The Role of Mathematics Member
2013/12 - 2018/12	Editorial Board Member: International Journal of Diagnostic Imaging Member
2016 - 2016	Program Committee ICIAR 2016: International Conference on Image Analysis and Recognition Member
2015 - 2015	Program Committee ICIAR 2015: International Conference on Image Analysis and Recognition Member
2014 - 2014	Program Committee ICIAR 2014: International Conference on Image Analysis and Recognition Member
2013 - 2013	Program Committee ICHI 2013: The International Conference on Health Informatics Member
2013 - 2013	Program Committee ICIAR 2013: International Conference on Image Analysis and Recognition Member
2012 - 2012	Program Committee ICIAR 2012: International Conference on Image Analysis and Recognition Member

Conference scientific committee

	Conference name	Conference host
2022 - 2022	EMBC 2022: Engineering in Medicine and Biology Society	Glasgow, UK
2022 - 2022	IMPROVE - International Conference on Image Processing and Vision Engineering	Online Streaming
2021 - 2021	EMBC 2021: Engineering in Medicine and Biology Society	Online Streaming
2021 - 2021	CSA - 7th Annual International Conference on Computer Science and Applications	Xiamen, China
2021 - 2021	IMPROVE - International Conference on Image Processing and Vision Engineering	Online Streaming
2021 - 2021	ISAIC - 2nd International Symposium on Automation, Information and Computing	Online Streaming
2020/07/20 - 2020/07/24	EMBC 2020: International Engineering in Medicine and Biology Conference	Montréal, Canada
2020/06/24 - 2020/06/26	ICIAR 2020: International Conference on Image Analysis and Recognition	Póvoa do Varzim, Portugal
2019/05 - 2019/05	MEDICON 2019: XV Mediterranean Conference on Medical and Biological Engineering and Computing	Coimbra, Portugal
2019/02/22 - 2019/02/23	6th Portuguese BioEngineering Meeting	Lisboa, Portugal
2019 - 2019	EMBC 2019: International Engineering in Medicine and Biology Conference	Berlin, Germany
2018 - 2018	EMBC 2018: International Engineering in Medicine and Biology Conference	Honolulu, Hawaii, USA
2018 - 2018	ICIAR 2018: International Conference on Image Analysis and Recognition	Póvoa de Varzim, Portugal
2018 - 2018	BHI 2018: IEEE EMBS International Conference on Biomedical & Health Informatics (BHI)	Las Vegas, Nevada, USA
2017/02/16 - 2017/02/18	5th Portuguese BioEngineering Meeting	Coimbra, Portugal
2017 - 2017	BHI 2017: IEEE EMBS International Conference on Biomedical & Health Informatics (BHI)	Orlando, Florida, USA
2017 - 2017	EMBC 2017: International Engineering in Medicine and Biology Conference	Jeju Island, Korea
2016 - 2016	EMBC 2016: International Engineering in Medicine and Biology Conference	Orlando, Florida USA
2016 - 2016	ICIAR 2016: International Conference on Image Analysis and Recognition	Póvoa de Varzim, Portugal
2015/02/26 - 2015/02/28	4th Portuguese BioEngineering Meeting	Porto, Portugal
2015 - 2015	EMBC 2015: International Engineering in Medicine and Biology Conference	Milan, Italy
2014 - 2014	EMBC 2014: International Engineering in Medicine and Biology Conference	Chicago, Illinois, USA
2014 - 2014	ICIAR 2014: International Conference on Image Analysis and Recognition	Vilamoura, Portugal
2014 - 2014	BHI 2014: The International Conference on Biomedical and Health Informatics	Valencia, Spain
2013/02/20 - 2013/02/22	3rd Portuguese Bioengineering Meeting	Braga, Portugal
2013 - 2013	EMBC 2013: International Engineering in Medicine and Biology Conference	Osaka, Japan
2013 - 2013	ICIAR 2013: International Conference on Image Analysis and Recognition	Póvoa de Varzim, Portugal
2012/02/23 - 2012/02/25	2nd Portuguese Bioengineering Meeting	Coimbra, Portugal
2012 - 2012	EMBC 2012: International Engineering in Medicine and Biology Conference	San Diego, California, USA
2012 - 2012	ICIAR 2012: International Conference on Image Analysis and Recognition	Aveiro, Portugal
2012 - 2012	ICCES 2012: The 2012 International Conference on Computer Engineering & Systems	Cairo, Egypt
2011/03/01 - 2011/03/04	1st Portuguese Bioengineering Meeting	Lisboa Portugal
2010 - 2010	CNSM 2010: International Conference on Networks Service Research	Niagara Falls, Canada
2010 - 2010	CNSR 2010: 8th Annual Conference on Communication Networks and Services Research	Montreal, Canada

Consulting

	Activity description	Institution / Organization
2009/11 - 2010/05	ALCON Consultant, Fort Worth, TX, USA	Alcon Research Institute, United States

Course / Discipline taught

	Academic session	Degree Subject (Type)	Institution / Organization
2018 - Current	Identificação e Validação de Biomarcadores em Imagem Médica	(Doutoramento)	Faculdade de Medicina, Universidade de Coimbra, Portugal
2013/02 - Current	Curso Avançado de Ciências da Visão	Ciências da Visão (Doutoramento)	Faculdade de Medicina, Universidade de Coimbra, Portugal
2011/09 - Current	Bioestatística	Mestrado Integrado em Engenharia Biomédica (Mestrado)	Faculdade de Medicina, Universidade de Coimbra, Portugal
2008/09 - Current	Bioquímica da Imagem	Mestrado Integrado em Engenharia Biomédica (Mestrado)	Faculdade de Medicina, Universidade de Coimbra, Portugal
2008/09 - Current	Modelos Computacionais de Processos Fisiológicos	Mestrado Integrado em Engenharia Biomédica (Mestrado)	Faculdade de Medicina, Universidade de Coimbra, Portugal
2007/09 - Current	Análise e Processamento de Imagem	Mestrado Integrado em Engenharia Biomédica (Mestrado)	Faculdade de Medicina, Universidade de Coimbra, Portugal
2007/09 - Current	Dosimetria da Radiação e Radiobiologia	Mestrado Integrado em Engenharia Biomédica (Mestrado)	Faculdade de Medicina, Universidade de Coimbra, Portugal
2007/09 - Current	Fundamentos de Imagem, Diagnóstico e Terapêutica	Mestrado Integrado em Engenharia Biomédica (Mestrado)	Faculdade de Medicina, Universidade de Coimbra, Portugal
2007/09 - Current	Visão Computacional e Percepção Biológica	Mestrado Integrado em Engenharia Biomédica (Mestrado)	Faculdade de Medicina, Universidade de Coimbra, Portugal
2008/09 - 2013	Informática Aplicada	Mestrado Integrado em Medicina (Mestrado)	Faculdade de Medicina, Universidade de Coimbra, Portugal
2007/09 - 2010/07	Image Processing and Analysis Master´s Vision´s Sciences	Ciências da Visão (Mestrado)	Faculdade de Medicina, Universidade de Coimbra, Portugal
2007/09 - 2010/07	Instrumentation, Image Processing and Analysis - PhD program in Vision´s Sciences	Ciências da Visão (Mestrado)	Faculdade de Medicina, Universidade de Coimbra, Portugal

Evaluation committee

	Activity description Role	Institution / Organization	Funding entity
2023 - 2023	PhD Studentships Evaluator	Fundação para a Ciência e a Tecnologia, Portugal	Fundação para a Ciência e a Tecnologia
2021 - 2021	H2020 projectos Evaluator
2020 - 2021	Petar Beron Specialist	Fond Naucni izsledvania, Bulgaria
2020 - 2020	H2020 monitor de projecto Specialist	European Commission, Belgium
2020 - 2020	H2020 projectos Evaluator	European Commission, Belgium
2020 - 2020	CHIST-ERA Specialist		Agence Nationale de la Recherce
2019 - 2019	H2020 projectos Evaluator	European Commission, Belgium
2019 - 2019	H2020 monitor de projecto Specialist	European Commission, Belgium
2018 - 2018	H2020 projectos Evaluator	European Commission, Belgium
2017 - 2017	Portugal Ventures Specialist
2017 - 2017	H2020 projectos Evaluator	European Commission, Belgium
2016 - 2016	H2020 projectos Evaluator	European Commission, Belgium
2015 - 2015	H2020 projectos Evaluator	European Commission, Belgium
2014 - 2015	Fundação de Amparo à Pesquisa do Estado de São Paulo Evaluator	Fundação de Amparo à Pesquisa do Estado de São Paulo, Brazil
2014 - 2014	H2020 projectos Evaluator	European Commission, Belgium
2013 - 2013	FP7 projectos Evaluator	European Commission, Belgium
2012 - 2012	FP7 projectos Evaluator	European Commission, Belgium
2011 - 2011	The Netherlands Organisation for Health Research and Development (ZonMw) Specialist	ZonMw, Netherlands

Journal scientific committee

	Journal title (ISSN)	Publisher
2022 - Current	Computer Methods in Biomechanics and Biomedical Engineering	Taylor & Francis
2021 - Current	Aging
2021 - Current	Acta Neuropathologica Communications
2021 - Current	Frontiers Cellular Neuroscience	Frontiers
2020 - Current	Health and Technology (2190-7196)	Springer-Verlag
2020 - Current	BMC Ophthalmology (1471-2415)	Springer (Biomed Central Ltd.)
2020 - Current	Translational Vision Science & Technology	IOVS
2019 - Current	Medical & Biological Engineering & Computing (1741-0444)	Springer-Verlag
2019 - Current	Symmetry (2073-8994)	MDPI AG
2018 - Current	Biomedical & Pharmacology Journal (2456-2610)	Oriental Scientific Publishing Company
2015 - Current	Computational and Mathematical Methods in Medicine	Hindawi
2015 - Current	Signal and Image Processing of Physiological Data: Methods for Diagnosis and Treatment Purposes	Hindawi
2013 - Current	PLOS ONE	PLOS
2013 - Current	Computers in Biology and Medicine	Elsevier
2013 - Current	Journal of Applied Scientific Reports (Appl Sci Rep)	Herbert Publications
2012 - Current	Scientific Reports (2045-2322)	Springer Nature
2010 - Current	Ophthalmologica - The Journal of the European Society of Retina Specialists	S. Karger AG
2010 - Current	BioMedical Engineering OnLine
2010 - Current	IEEE Journal of Biomedical and Health Informatics (J-BHI)	IEEE Computer Society & Engineering in Medicine and Biology Society
2009 - Current	Computer Methods and Programs in Biomedicine	Elsevier
2019 - 2019	Journal of Neurology (1432-1459)	Springer-Verlag
2019 - 2019	Journal of Imaging (2313-433X)	MDPI AG
2019 - 2019	Applied Sciences (2076-3417)	MDPI AG
2011 - 2019	European Journal of Ophthalmology	Wichtig Editore
2008 - 2019	Investigative Ophthalmology & Visual Science (IOVS)	IOVS
2018 - 2018	Biomedical & Pharmacology Journal (0974-6242)	Content Specialist
2013 - 2018	International Journal of Diagnostic Imaging (IJDI)	Sciedu Press
2012 - 2018	Computerized Medical Imaging and Graphics	Elsevier
2011 - 2018	Biomedical Optics Express	Optical Society of America
2004 - 2018	IEEE Transactions on Medical Imaging	http://www.ieee.org/
2011 - 2017	IEEE Transactions on Image Processing	http://www.ieee.org/index.html?WT.mc_id=hpf_logo
2015 - 2015	Journal of Biophotonics
2012 - 2012	Journal of Biomedical Optics	SPIE
2012 - 2012	International Journal of Computers and Applications (1925-7074)	Informa UK (Taylor & Francis)
2010 - 2012	Ophthalmic Research	S. Karger AG
2010 - 2012	International Journal for Numerical Methods in Biomedical Engineering	John Wiley & Sons Ltd
2010 - 2012	IEEE Transactions on Biomedical Engineering	IEEE Engineering in Medicine and Biology Society

Distinctions

Award

2019	Fraunhofer Portugal Best Paper Award (paper's senior author) Associação Fraunhofer Portugal Research, Portugal
2019	Young Investigator Competition Award (paper's senior author) - MEDICON
2015	Prémio Mantero Belard (team member) Santa Casa da Misericórdia de Lisboa, Portugal
2006	Pfizer Portugal 2006 (Clinical Investigation): Novel Retinal Mechanisms Underlying Genetically Determined Neural Dysfunction in Williams-Beuren Syndrome Pfizer - Portugal, Portugal
2003	Best Poster of the Day - Computer-assisted microaneurysms counting on digitized retinographies. EVER, Portugal

Title

2023	EVER Fellow European Association for Vision and Eye Research, Belgium
2014	IEEE Senior Member IEEE, United States
2006	ALCON Principal Investigator at AIBILI in Macular Degeneration and Glaucoma Alcon Portugal Produtos e Equipamentos Oftalmológicos LDA, Portugal

Other distinction

2019	Keynote Speaker – XV Mediterranean Conference on Medical and Biological Engineering and Computing (MEDICON), Coimbra, Portugal.
2011	Who’s Who in the World 2011, 28th Edition Who’s Who in the World 2011, Portugal