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Maria Joana Faustino Pinheiro completed the Degree in Biochemistry in 2017 and the Master in Biotechnology in 2019. The Master's thesis focused on the synthesis of new molecules with anti-Candida activity and functionalization of coatings in order to prevent the colonization of surfaces and formation of biofilms. In addition, the resistance mechanisms of Candida albicans isolates were explored, as well as the beginning of the genetic characterization of an environmental isolate of Candida glabrata. She published 2 articles in journals, presented 2 posters at national events and participated in the organization of 3 events. After completing her master's degree, she participated in the research project funded by FCT LactoCan as a research fellow at the Institute of Bioengineering and Biosciences of Instituto Superior Técnico. Currently, she is undertaking a PhD program at the Institute of Bioengineering and Biosciences of Instituto Superior Técnico.
Identification

Personal identification

Full name
Maria Joana Faustino Pinheiro

Citation names

  • Pinheiro, Maria

Author identifiers

Ciência ID
DA1C-0235-4037

Knowledge fields

  • Natural sciences - Biological Sciences - Biology
  • Natural sciences - Biological Sciences - Biochemistry
  • Natural sciences - Biological Sciences - Microbiology

Languages

Language Speaking Reading Writing Listening Peer-review
English Intermediate (B1) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Elementary (A2) Intermediate (B1)
Education
Degree Classification
2021/04 - 2025
Ongoing
Biotecnologia e Biociências (Doutoramento)
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
2017 - 2019
Concluded
Biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
18
2014 - 2017
Concluded
Bioquímica (Licenciatura)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
"Dinâmica da localização do factor NF-kB em células HeLa estimuladas com TNF-a" (THESIS/DISSERTATION)
14
Affiliation

Science

Category
Host institution
Employer
2020/09 - 2021/03 Research Assistant (Research) Laboratório para o Diagnóstico Laboratorial da COVID-19 Do Instituto Superior Técnico, Portugal
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/01 - 2020/07 Research Assistant (Research) Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018/05 - 2018/07 Research Trainee (Research) Stem Cell Engineering Research Group , Portugal
Universidade de Lisboa Instituto Superior Técnico, Portugal

Others

Category
Host institution
Employer
2019 - Current Volunteering in an association that promotes animal welfare Associação dos Animais de Lisboa, Portugal
Associação dos Animais de Lisboa, Portugal
2019/04 - 2019/12 Baby-sitting services in a daycare facility Stellaria, Portugal
Projects

Contract

Designation Funders
2023/03/01 - 2026/02/28 SMARTWINE 2.0 ¿ Desenvolvimento de Leveduras starter para a produção de vinhos estilísticos sustentavelmente preservados
2022.06777.PTDC
Universidade de Trás-os-Montes e Alto Douro, Portugal

Universidade de Lisboa Centro de Ecologia Evolução e Alterações Ambientais, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade Católica Portuguesa, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2020/01 - 2020/07 LactoCan – Exploring the interference between Candida spp. and Lactobacilii to foster the development of non-conventional antifungal therapies
PTDC/BIA-MIC/31515/2017
Research Fellow
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento
Ongoing
Outputs

Publications

Conference poster
  1. Salazar, Sara; Pinheiro, Maria. "Comparative OMICs analyses of azole-resistant Candida glabrata clinical strains reveals adaptive responses, dependent and independent of CgPdr1, in the acquisition of the resistance phenotype". Paper presented in MicroBiotec23, 2023.
  2. Pinheiro, Maria. "Exploring comparative genomics to elucidate the adaptation of the pathogenic yeast Candida glabrata to the human host". Paper presented in III iBB Workshop 2023, 2023.
  3. Pinheiro, Maria. "Exploring comparative genomics to elucidate the adaptation of the pathogenic yeast Candida glabrata to the human host". Paper presented in II iBB Workshop 2023, 2022.
  4. Joana P. Costa; M. Fernanda N. N. Carvalho; Pinheiro, Maria; Adelino M. Galvão; Jorge H. Leitão. "Design and synthesis of silver camphorimine compounds with high antimicrobial activity". Paper presented in XXVI Encontro Nacional da Sociedade Portuguesa de Química. P11, 2019.
  5. Joana P. Costa; Pinheiro, Maria; M. Fernanda NN Carvalho. "Camphor complexes with antimicrobial and/or cytotoxic properties: design, synthesis and assessment of biological activity". Paper presented in CQE Days Spring Meeting 2019. P37, 2019.
Journal article
  1. Mira, Nuno Pereira; Marshall, Robert; Pinheiro, Maria Joana F; Dieckmann, Ralf; Dahouk, Sascha Al; Skroza, Nevena; Rudnicka, Karolina; Lund, Peter A; De Biase, Daniela. "On the potential role of naturally occurring carboxylic organic acids as anti-infective agents: opportunities and challenges". International Journal of Infectious Diseases 140 (2024): 119-123. http://dx.doi.org/10.1016/j.ijid.2024.01.011.
    10.1016/j.ijid.2024.01.011
  2. Salazar, Sara; Pinheiro, Maria; Mira, Nuno Pereira; FERNANDES, FABIO. "Disclosing azole resistance mechanisms in resistant Candida glabrata strains encoding wild-type or gain-of-function CgPDR1 alleles through comparative genomics and transcriptomics". G3 Genes|Genomes|Genetics 12 7 (2022):
    Published
  3. Salazar; Simões; Pedro; Pinheiro; Carvalho; Mira. "An Overview on Conventional and Non-Conventional Therapeutic Approaches for the Treatment of Candidiasis and Underlying Resistance Mechanisms in Clinical Strains". Journal of Fungi 6 1 (2020): 23. http://dx.doi.org/10.3390/jof6010023.
    10.3390/jof6010023
  4. Costa, Joana P.; Pinheiro, M. Joana F.; Sousa, Sílvia A.; Botelho do Rego, Ana M.; Marques, Fernanda; Oliveira, M. Conceição; Leitão, Jorge H.; P. Mira, Nuno; N. N. Carvalho, M. Fernanda. "Antimicrobial Activity of Silver Camphorimine Complexes against Candida Strains". Antibiotics 8 3 (2019): 144. http://dx.doi.org/10.3390/antibiotics8030144.
    10.3390/antibiotics8030144
Thesis / Dissertation
  1. Pinheiro, Maria. "Developing novel anti-Candida therapies through the understanding of drug-resistance mechanisms and by tailoring new chemicals to be used in anti-biofilm surfaces". Master, Universidade de Lisboa Instituto de Bioengenharia e Biociências, 2019.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/09/21 Unraveling new mechanisms governing azole resistance mechanisms in clinical Candida glabrata strains: beyond CgPdr1 XXII Jornadas de Biologia de Leveduras Professor Nicolau van Uden
(Coimbra, Portugal)
2023 Phenotypic, physiological and genomic portrait of a “human-naive” Candida glabrata strain: A shed of light into the path towards colonization of the human host MicroBiotec23
Universidade da Beira Interior

Event organisation

Event name
Type of event (Role)
Institution / Organization
2025/04/05 - 2025/04/05 The doors of the Alameda campus in Lisbon are open to visitors for a unique opportunity to explore the learning and research taking place across Técnico’s three campuses. The event will showcase projects by students, researchers, and professors, and offer guided visits to laboratories, along with insights into the academic programs offered by the Schoo (2025/04/05 - 2025/04/05)
Workshop (Other)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2020/01/20 - 2020/02/16 EuroMicropH - Cost Action had the central objective of bringing together people from different fields, but with a common scientific interest: understanding and exploring the responses of microorganisms to low pH. This topic is being studied in depth and has several important practical applications in different sectors. (2020/02/12 - 2020/02/14)
Congress (Member of the Organising Committee)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018/10/25 - 2019/03/31 The 5th Semana da Bioengenharia of the Instituto Superior Técnico (SBE IST) emerged as an initiative of the students of the Masters in Biomedical Engineering, Biological Engineering, Biotechnology and Microbiology. Its mission has been to strengthen the relationship between the academic community and the business world / scientific community. The event has a set of lectures given by researchers and companies, national and international, in the area of bioengineering, study visits, workshops, among other activities. (2019/03/18 - 2019/03/22)
Conference (President of the Organising Committee)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017/12/01 - 2018/03/11 The 4th Semana da Bioengenharia of the Instituto Superior Técnico (SBE IST) emerged as an initiative of the students of the Masters in Biomedical Engineering, Biological Engineering, Biotechnology and Microbiology. Its mission has been to strengthen the relationship between the academic community and the business world / scientific community. The event has a set of lectures given by researchers and companies, national and international, in the area of bioengineering, study visits, workshops, among other activities. (2018/03/05 - 2018/03/09)
Conference (Member of the Scientific Committee)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2024/04/04 - 2024/04/05 The event covers antifungal resistance in plants, crops and agriculture, human and animal health, and urban environments, with the participation of scientists from all over the world.
Congress
One Health and the Challenge of Antifungal Resistance
2019/07/24 - 2019/07/26 XXVI Encontro Nacional da Sociedade Portuguesa de Química
Congress
XXVI Encontro Nacional da Sociedade Portuguesa de Química
Universidade do Porto Faculdade de Ciências, Portugal
2019/07/16 - 2019/07/16 The secret universe of our microbes - The Conference aims to promote the knowledge generated in different research groups dedicated to study the profound impact of bacteria in our lives, but also in the lives of other animals and plants.
Seminar
Instituto Gulbenkian de Ciência, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2024/02/06 - Current Computational Biosciences using HPC systems Unidade de Ciências Biomoleculares Aplicadas, Portugal

Infraestrutura Nacional de Computação Distribuída, Portugal
2022/02/07 - Current Specialization course in Radiological Protection and Safety - level III Universidade de Lisboa Instituto Superior Técnico, Portugal

Scientific expedition

Activity description Institution / Organization
2023/04 - Current Period of studies abroad in Prof Kyle cunningham's laboratory, with the aim of learning and how to apply Hermes transposons-based libraries to assess the effect of genetic background in C. glabrata tolerance to azoles. Johns Hopkins University Department of Biology, United States