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Ana Cláudia Nunes Carreira. Graduated in Cell and Molecular Biology, Faculty of Sciences and Technology (New University of Lisbon) and PhD in Pharmacy, Faculty of Pharmacy (Lisbon University). During the last few years I had the opportunity to develop my technical and scientific skills in different but complementary working areas, including: Cellular and Molecular Biology, Microbiology, Pharmaceutical Technology, Quality control and Bioprocessing.
Identification

Personal identification

Full name
ANA CLÁUDIA NUNES CARREIRA

Citation names

  • Carreira, Ana

Author identifiers

Ciência ID
DA14-5D79-8362
ORCID iD
0000-0003-4069-8530

Knowledge fields

  • Natural sciences - Biological Sciences - Molecular Biology
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Natural sciences - Biological Sciences - Biophysics
  • Natural sciences - Biological Sciences - Microbiology
  • Medical and Health Sciences - Health Sciences - Infectious Diseases
  • Engineering and Technology - Industrial Biotechnology - Bioprocessing Technologies

Languages

Language Speaking Reading Writing Listening Peer-review
English Upper intermediate (B2) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Portuguese (Mother tongue)
Education
Degree Classification
2024/04 - 2024/06
Concluded
 Biotecnologia Ambiental (Outros)
Universidade de Lisboa Instituto Superior Técnico, Portugal
 18
2013/01 - 2019/02
Concluded
 Farmácia (Doutoramento)
Major in Especialidade: Tecnologia Farmacêutica
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Sphingosine-induced alterations in membrane biophysical properties: biological relevance in the pathophysiology of human disease " (THESIS/DISSERTATION)
 Aprovada com Louvor e Distinção
2015/10 - 2015/10
Concluded
 Quantitative Fluorescence Microscopy Course (Outros)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2009/09 - 2012/06
Concluded
 Sistemas de Prevenção e Controlo Alimentar (Mestrado)
Instituto Politécnico de Santarém Escola Superior Agrária, Portugal
"Characterization of Campylobacter jejuni and Campylobacter coli isolates obtained from broilers caeca, in Portugal, in the framework of a prevalence community study - Genotyping and elucidation of biofilm growth associated determinants. June 2012." (THESIS/DISSERTATION)
 18
2011/03 - 2011/03
Concluded
 Gulbenkian Training Programme in Bioinformatics (Outros)
Instituto Gulbenkian de Ciência, Portugal
2005/09 - 2008/09
Concluded
 Biologia Celular e Molecular (Licenciatura)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
 15
Affiliation

Science

Category
Host institution 		Employer
2022/02 - 2022/07 Contracted Researcher (Research) FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal
2017/04/03 - 2018/09/10 Researcher (Research) FARM-ID-Associação da Faculdade de Farmácia para a Investigação e o Desenvolvimento, Portugal
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2013/02/25 - 2017/02/28 Research Trainee (Research) Fundação para a Ciência e a Tecnologia, Portugal
Universidade de Lisboa Faculdade de Farmácia, Portugal

Other Careers

Category
Host institution 		Employer
2023/11 - Current Técnico Superior (Técnico Superior) Instituto Nacional de Investigação Agrária e Veterinária Polo de Santarém, Portugal

Others

Category
Host institution 		Employer
2019/10 - 2022/01 Indústria Farmacêutica - Controlo de Qualidade/Técnica de Investigação e Desenvolvimento Neutroplast, Portugal
Projects

Grant

Designation Funders
2017/04 - 2018/09 Biophysical and biological properties of atypical sphingolipids: implications to physiology and pathophysiology
PTDC/BBB-BQB/3710/2014
Research Fellow
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2023/11 - Current INSECTERA
C632327738-00466948
Technical development
Ongoing
2022/02/01 - 2022/06 EPIRaft - Contribution of neuronal membrane and lipid raft remodelling to the pathophysiology of mesial temporal lobe epilepsy (MTLE): insight into the beneficial effects of the ketogenic diet therapy.
POCI-01-0145-FEDER-028311
Technical development
Fundação para a Ciência e a Tecnologia
Concluded
2013/07 - 2015/12 Ceramide-Platforms: implication of membrane biophysical properties on ceramide biological outcome
PTDC/BBB-BQB/0506/2012
Technical development
Fundação para a Ciência e a Tecnologia
Concluded
2010/09 - 2012/06 MyPATH- Insights into Mycobacterium tuberculosis complex PATHogenesis: assessing the benefit of confinement-induced biofilm strategies by comparative genomics
PTDC/CVT/117794/2010
Technical development
Fundação para a Ciência e a Tecnologia
Outputs

Publications

Book chapter
  1. Ana E. Ventura; Tânia Santos; Ana C. Carreira; Nuno M. Martinho; J. Conniot; Ana R. Varela; Rogério Gaspar; Helena F. Florindo; Liana C. Silva. Corresponding author: Liana C. Silva. "Drugs, delivery systems and membrane organization in model and cell membranes. In: Membrane organization and lipid rafts in the cell and artificial membranes.". Nova Science Publishers Inc, 2020.
  2. Carreira AC; Cunha MV. "Characterization of Campylobacter jejuni and Campylobacter coli genotypes in poultry flocks by restriction fragment length polymorphism (RFLP) analysis.". In Methods in molecular biology (Clifton, N.J.). 2015.
    10.1007/978-1-4939-2004-4_22
Journal article
  1. Carreira, Ana C.; Pokorna, Sarka; Ventura, Ana E.; Walker, Mathew W.; Futerman, Anthony H.; Lloyd-Evans, Emyr; de Almeida, Rodrigo F.M.; Silva, Liana C.. Corresponding author: Silva, Liana C.. "Biophysical impact of sphingosine and other abnormal lipid accumulation in Niemann-Pick disease type C cell models". Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1866 8 (2021): 158944. http://dx.doi.org/10.1016/j.bbalip.2021.158944.
    10.1016/j.bbalip.2021.158944
  2. Carreira, A.C.; Santos, T.C.; Lone, M.A.; Zupancic, E.; Lloyd-Evans, E.; de Almeida, R.F.M.; Hornemann, T.; Silva, L.C.. Corresponding author: Silva, L.C.. "Mammalian sphingoid bases: Biophysical, physiological and pathological properties". Progress in Lipid Research 75 (2019): 100988. http://dx.doi.org/10.1016/j.plipres.2019.100988.
    10.1016/j.plipres.2019.100988
  3. Dos Santos AG; Marquês JT; Carreira AC; Castro IR; Viana AS; Mingeot-Leclercq MP; de Almeida RFM; Silva LC. "The molecular mechanism of Nystatin action is dependent on the membrane biophysical properties and lipid composition.". Physical chemistry chemical physics : PCCP (2017): http://europepmc.org/abstract/med/29098221.
    10.1039/c7cp05353c
  4. Carreira AC; de Almeida RFM; Silva LC. "Development of lysosome-mimicking vesicles to study the effect of abnormal accumulation of sphingosine on membrane properties.". Scientific reports (2017): http://europepmc.org/abstract/med/28638081.
    10.1038/s41598-017-04125-6
  5. Varela AR; Ventura AE; Carreira AC; Fedorov A; Futerman AH; Prieto M; Silva LC. "Pathological levels of glucosylceramide change the biophysical properties of artificial and cell membranes.". Physical chemistry chemical physics : PCCP (2016): http://europepmc.org/abstract/med/27905603.
    10.1039/c6cp07227e
  6. Carreira AC; Ventura AE; Varela AR; Silva LC. "Tackling the biophysical properties of sphingolipids to decipher their biological roles.". Biological chemistry (2015): http://europepmc.org/abstract/med/25581755.
    10.1515/hsz-2014-0283
  7. Zupancic E; Carreira AC; de Almeida RF; Silva LC. "Biophysical implications of sphingosine accumulation in membrane properties at neutral and acidic pH.". The journal of physical chemistry. B (2014): http://europepmc.org/abstract/med/24731183.
    10.1021/jp501167f
  8. Carreira, Ana Cláudia; Clemente, Lurdes; Rocha, Teresa; Tavares, Alcina; Geraldes, Margarida; Barahona, Maria José; Botelho, Ana; Cunha, Mónica V.. Corresponding author: Cunha, Mónica V.. "Comparative Genotypic and Antimicrobial Susceptibility Analysis of Zoonotic Campylobacter Species Isolated from Broilers in a Nationwide Survey, Portugal". Journal of Food Protection 75 12 (2012): 2100-2109. http://dx.doi.org/10.4315/0362-028x.jfp-12-183.
    10.4315/0362-028x.jfp-12-183
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2015/07/15 Effect of sphingosine on the biophysical properties and permeability of raft-mimicking mixtures. 7 th iMed.ULisboa Postgraduate Students Meeting Postgraduate Students Meeting
Faculdade de Farmácia, Universidade de Lisboa (Lisboa, Portugal)

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2017/07/13 - 2017/07/14 Poster presentation - Ana C. Carreira, Rodrigo F. M. de Almeida and Liana C. Silva. Lysosomal-mimicking vesicles are a valuable tool to understand physiological and pathological processes involving the lysosomal membrane
Meeting
 9 th iMed.ULisboa Postgraduate Students Meeting & 2nd i3DU Students Meeting
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017/05/31 - 2017/05/31 Poster presentation - Ana C. Carreira, Rodrigo F. M. de Almeida and Liana C. Silva. Lysosomal-mimicking vesicles: a valuable tool to explore the effect of sphingosine abnormal accumulation on membrane biophysical properties.
Meeting
 CQB day
Universidade de Lisboa Faculdade de Ciências, Portugal
2017/02/09 - 2017/02/09 Poster presentation - Ana C. Carreira, Rodrigo F. M. de Almeida and Liana C. Silva. Development of lysosome-mimicking vesicles to study the effect of sphingosine abnormal accumulation on membrane permeability and biophysical properties.
Meeting
 Chem&BioChem Postgraduate Students Meeting
Universidade de Lisboa Faculdade de Ciências, Portugal
2016/09/01 - 2016/09/02 Poster presentation - Ana C. Carreira, Rodrigo F. M. de Almeida and Liana C. Silva. Development of lysosome-mimicking vesicles to study the effect of sphingosine abnormal accumulation on membrane permeability and biophysical properties.
Meeting
 EMBO Young Scientists' Forum 2016
Fundação Calouste Gulbenkian, Portugal
2016/07/14 - 2016/07/15 Poster presentation - Ana C. Carreira, Rodrigo F. M. de Almeida and Liana C. Silva. The effect of sphingosine on membrane permeability and biophysical properties of lysosome-mimicking vesicles.
Meeting
 8 th iMed.ULisboa Postgraduate Students Meeting & 1st i3DU Students Meeting
Universidade de Lisboa Faculdade de Farmácia, Portugal
2016/07/04 - 2016/07/06 Poster presentation - Ana C. Carreira, Rodrigo F. M. de Almeida and Liana C. Silva. Development of lysosome-mimicking vesicles to study the effect of sphingosine abnormal accumulation on membrane permeability and biophysical properties.
Meeting
 Encontro Ciência 2016
Centro de Congressos de Lisboa, Portugal
2016/06/28 - 2016/06/28 Poster presentation - Ana C. Carreira, Rodrigo F. M. de Almeida and Liana C. Silva. Development of lysosomal-mimicking vesicles to study the effect of sphingosine abnormal accumulation on membrane biophysical properties.
Meeting
 CQB day
Universidade de Lisboa Faculdade de Ciências, Portugal
2016/06/15 - 2016/06/17 Poster presentation - Ana C. Carreira, Rodrigo F. M. de Almeida and Liana C. Silva. Effect of Sphingosine on the membrane permeability and biophysical properties of lysosomal-mimicking vesicles.
Congress
 5 th International Iberian Biophysics Congress
Sociedade Portuguesa de Biofísica, Portugal
2015/09/15 - 2015/09/15 Poster presentation - Ana C. Carreira, Rodrigo F. M. de Almeida and Liana C. Silva. Modulation of the biophysical properties and permeability of model membranes by sphingosine.
Meeting
 CQB day
Universidade de Lisboa Faculdade de Ciências, Portugal
2015/05/06 - 2015/05/10 Poster presentation - Ana C. Carreira, Eva Zupancic, Rodrigo F. M. de Almeida and Liana C. Silva. Effect of sphingosine on the biophysical properties and permeability of raft-mimicking mixtures.
Conference
 International Ceramide Conference - Sphingolipid Club / Joint Meeting
2014/09/14 - 2014/09/14 Poster presentation - Ana C. Carreira, Eva Zupancic, Rodrigo F. M. de Almeida and Liana C. Silva. Niemann-Pick disease type C: implication of sphingosine accumulation on membrane biophysical properties and permeability.
Symposium
 Sphingolipids in Health and Disease, Symposium IBMC
Instituto de Biologia Molecular e Celular, Portugal
2014/07/09 - 2014/07/09 Poster presentation - Ana C. Carreira, Eva Zupancic, Rodrigo F. M. de Almeida and Liana C. Silva. Implication of Sphingosine accumulation on membrane biophysical properties: influence of pH environment and surface electrical charge.
Meeting
 CQB day
Universidade de Lisboa Faculdade de Ciências, Portugal
2014/07/02 - 2014/07/02 Poster presentation - Ana C. Carreira, Eva Zupancic, Rodrigo F. M. de Almeida and Liana C. Silva. Implication of Sphingosine accumulation on membrane biophysical properties: influence of pH environment and surface electrical charge.
Meeting
 6 th iMed.UL Postgraduate Students Meeting
Universidade de Lisboa Faculdade de Farmácia, Portugal
2014/06/02 - 2014/06/06 Poster presentation - Ana C. Carreira, Eva Zupancic, Rodrigo F. M. de Almeida and Liana C. Silva. Implication of sphingosine accumulation on membrane biophysical properties: influence of pH environment and surface electrical charge.
Workshop
 Cellular Imaging of Lipids, EMBO workshop
2013/12/06 - 2013/12/08 Poster presentation - Ana C. Carreira and Mónica Vieira Cunha. Biofilm formation by Campylobacter jejuni and Campylobacter coli in abiotic surfaces: elucidation of environmental determinants associated to persistence in the food chain.
Congress
 Microbiotec13
Universidade de Aveiro, Portugal
2013/09/20 - 2013/09/21 Poster presentation - Ana C. Carreira, Eva Zupancic, Rodrigo F. M. de Almeida and Liana C. Silva. Influence of sphingosine accumulation on membrane biophysical properties: relation to Niemann-Pick disease type C.
Congress
 The Iberian Membrane Biophysics Colloquium: Physics and Biology Meet at the Cell Membrane
CIC biomaGUNE, Spain
2013/07/18 - 2013/07/18 Poster presentation - Ana C. Carreira, Eva Zupancic, Rodrigo F. M. de Almeida and Liana C. Silva. Niemann-Pick Disease Type C: The Effects of Sphingosine Accumulation on Membrane Biophysical Properties.
Meeting
 5 th iMed.UL Postgraduate Students Meeting
Universidade de Lisboa Faculdade de Farmácia, Portugal
2013/07/13 - 2013/07/18 Poster presentation - Ana C. Carreira, Eva Zupancic, Rodrigo F. M. de Almeida and Liana C. Silva. Niemann-Pick disease type C: sphingosine accumulation affects membrane biophysical properties.
Congress
 9 th EBSA European Biophysics Congress
2013/07/04 - 2013/07/04 Poster presentation - Ana C. Carreira, Eva Zupancic, Rodrigo F. M. de Almeida and Liana C. Silva. Influence of sphingosine accumulation on membrane biophysical properties: relation to Niemann-Pick disease type C.
Meeting
 CQB day
Universidade de Lisboa Faculdade de Ciências, Portugal
2011/12/01 - 2011/12/03 Poster presentation - Ana C. Carreira, Teresa Rocha, Margarida Geraldes, Maria José Barahona, Lurdes Clemente, Ana Botelho, and Mónica V. Cunha. Molecular analysis of Campylobacter jejuni and Campylobacter coli from a nationwide survey performed on broilers: flaA typing and prevalence of potentially neuropathic strains.
Congress
 Microbiotec11
Universidade do Minho, Portugal
2011/10/13 - 2011/10/15 Poster presentation - Ana C. Carreira, Teresa Rocha, Alcina Tavares, Margarida Geraldes, Maria José Barahona, Lurdes Clemente, Ana Botelho, and Mónica Vieira Cunha. Comparative genotypic analysis of zoonotic Campylobacter jejuni and Campylobacter coli field isolates from a nationwide survey conducted on broilers.
Congress
 V Congresso da Sociedade Portuguesa de Ciências Veterinárias
Instituto Nacional de Investigação Agrária e Veterinária, Portugal

Association member

Society Organization name Role
2021 - Current Ordem dos Biólogos
2013 - 2018 Associação Portuguesa de Bioquímica
Distinctions

Award

2015 Bolsa para participação em International Ceramide Conference - Sphingolipid Club/Joint Meeting
2014 Bolsa para participação em Cellular Imaging of Lipids, EMBO workshop
2013 Bolsa de Doutoramento FCT - SFRH/BD/88194/2012
Fundação para a Ciência e a Tecnologia, Portugal
2013 Bolsa para participação em The Iberian Membrane Biophysics Colloquium: Physics and Biology Meet at the Cell Membrane