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Identification

Personal identification

Full name
Nuno Martinho

Citation names

  • Martinho, Nuno

Author identifiers

Ciência ID
D51E-5772-FF5F

Email addresses

  • nunomartinho@tecnico.ulisboa.pt (Professional)

Addresses

  • imed - Research Institute for Medicines, Universidade de Lisboa, Lisboa, 1600-277, Lisbon, Lisbon, Portugal (Professional)

Knowledge fields

  • Engineering and Technology - Nano-technology
  • Exact Sciences - Chemical Sciences - Polymer Science
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
French Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2)
Education
Degree Classification
2022/03
Concluded
 Pedagogical Skills for Teaching Assistants (Outros)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/06/30 - 2021/07/03
Concluded
 Manipulation and analysis of gene expression (Outros)
Universidade Lusófona de Humanidades e Tecnologias Escola de Ciências e Tecnologias da Saúde, Portugal
2020
Concluded
 Laboratory Animals Science (Category B) (Pós-Graduação)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018
Concluded
 Pharmaceutical Technology (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Fluorescent-based dendrimers as potential drug delivery carriers of cisplatin: from design and synthesis to platinum-membrane interactions" (THESIS/DISSERTATION)
2012
Concluded
 Master in Pharmaceutical Sciences (Mestrado)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
"Drug delivery systems of NO-donors for oral administration" (THESIS/DISSERTATION)
 16
2012
Concluded
 Basic Concepts of Cell Culture (Pós-Graduação)
Grupo Lusófona, Portugal
Affiliation

Science

Category
Host institution 		Employer
2023 - 2024 Contracted Researcher (Research) Universidade de Lisboa Faculdade de Farmácia, Portugal
2021 - 2022 Contracted Researcher (Research) Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
2018/12/15 - 2020/06/14 Contracted Researcher (Research) Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
Projects

Grant

Designation Funders
2025 - Current TRIADD: "Smart Discovery Platform: Tailored and Rapid Discovery and Repurposing of Small Molecule Drugs using AI and in silico methods"
16049.MPr-2023-12/Fundos LISBOA2030-FEDER-00719600
Integration into Research Grant Fellow
Ongoing
2022 - Current Using a Genetic Algorithm to design new urease inhibitors
CPCA/A1/407814/2021
Co-Principal Investigator (Co-PI)
Fundação para a Ciência e a Tecnologia
Ongoing
2021/03/01 - Current Urease Next-Generation inhibition Therapy
PTDC/MED-QUI/3542/2020
Principal investigator
Fundação para a Ciência e a Tecnologia
2018 - 2021 Exploring the biophysical link between Gaucher disease and Parkinson’s diseas
PTDC/BIA-BFS/29448/2017
Integration into Research Grant Fellow

Contract

Designation Funders
2021/01/01 - 2025/12/31 Institute for Health and Bioeconomy
LA/P/0140/2020
10.54499/LA/P/0140/2020
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal

Universidade Nova de Lisboa, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

INESC Microsistemas e Nanotecnologias, Portugal

Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2019/01/01 - 2023/12/31 Applied Molecular Biosciences Unit
UIDP/04378/2020
10.54499/UIDP/04378/2020
UIDB/04378/2020
10.54499/UIDB/04378/2020
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal

Universidade Nova de Lisboa, Portugal

Universidade do Porto, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

INESC Microsistemas e Nanotecnologias, Portugal

Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/12/15 - 2020/06/15 Dendrimer-based Report-Eradication Antineoplasic Machines
PTDC/MEC-ONC/29327/2017
Researcher
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
 Fundação para a Ciência e a Tecnologia
2019/01/01 - 2019/12/31 Research Institute for Medicines
UID/DTP/04138/2019
Universidade de Lisboa Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016/05/02 - 2019/12/31 Biophysical and biological properties of atypical sphingolipids: implications to physiology and pathophysiology
PTDC/BBB-BQB/3710/2014
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

Universidade de Lisboa Centro de Química-Física Molecular, Portugal

Universität Zürich, Switzerland

Universidade de Lisboa Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Martinho, Nuno; Mire Zloh. "Modelling Approaches for Studies of Drug-Polymer Interactions in Drug Delivery Systems". In Computer Aided Pharmaceutics and Drug Delivery. Springer Singapore, 2022.
  2. Silva, Catarina Oliveira; Martinho, Nuno; Aniceto, Natália; Catarina Pinto Reis. "Melanoma Prevention: Challenges and Progresses in Nanotechnology for Melanoma Prevention and Treatment". In CRC Concise Encyclopedia of Nanotechnology, 477-494. CRC Press, 2016.
    10.1201/b19457-41
  3. Reis, Catarina; Martinho, Nuno; Damgé, Christiane. "Nanotechnology for Oral Drug Delivery and Targeting". In Nanotechnology and Drug Delivery, Volume Two, 20-51. CRC Press, 2016.
    10.1201/b19976-3
  4. Martinho, Nuno; Helena F Florindo; Ana Ester Ventura; Tânia Santos; Ana Carreira; João Conniot; Ana Raquel Varela; Rogério Gaspar. "Drugs, delivery systems and membrane organization in model and cell membranes". In Membrane organization and lipid rafts in the cell and artificial membranes. 2016.
Conference poster
  1. Ledesma-Martin, V; Assis, D. L.; Martinho, Nuno; Aniceto, Natália; Decker, M.; Guedes, Rita C.. "Generation and docking of a library of orexin ligand-inspired photoswitchable ligands to treat AD circadian dysfunction". Paper presented in 5th Biophysics Festival, 2025.
  2. Barzelai, Shira; Ledesma-Martin, V; Martinho, Nuno; Guedes, Rita C.. "Structure-Activity Relationship and Virtual Screening Approaches for Identifying Natural Product Modulators of Orexin Receptors". Paper presented in 5th Biophysics Festival, 2025.
  3. Barros, H. L.; Martinho, Nuno; Bonifácio, Vasco D.B.. "Design of Polyurea Dendrimers Towards Helicobacter pylori Urease Inhibition". Paper presented in MAD-Nano24, 2024.
  4. Vasco D.B. Bonifácio; Hélio Barros; Martinho, Nuno. "Polyurea dendrimers as inhibitors of urease activity in Helicobacter pylori". Paper presented in XXVIII Encontro Galego-Português, 2024.
  5. Vasco D.B. Bonifácio; Hélio Barros; Martinho, Nuno. "Advancements in Dendrimer-Based Therapeutics for Gastrointestinal Disease Treatment". Paper presented in International Conference on Gastroenterology and Functional Gastrointestinal Diseases (ICGFGD-24), 2024.
  6. Ledesma-Martin, V; Assis, D; Martinho, Nuno; Aniceto, N; Decker, M; Guedes, R. "Structure and ligand-based strategies to discover novel orexin receptor modulators: targeting the circadian clock and Alzheimer’s disease". Paper presented in 15th National Organic Chemistry Meeting, 2024.
  7. Assis, D; Ledesma-Martin, V; Martinho, Nuno; Guedes, R. "Revolution in Neuroscience: Innovating Alzheimer's Treatment with Photoswitchable Molecules". 2024.
  8. V. Ledesma-Martin; Diana L. Assis; Martinho, Nuno; Aniceto, Natália; M. Decker; Guedes, Rita C.. "Analysis of receptor-ligand interactions to discover orexin receptor photoswitches". Paper presented in XV iMed.ULisboa Postgraduate Students Meeting., 2024.
  9. Diana L. Assis; V. Ledesma-Martin; Martinho, Nuno; Aniceto, Natália; Guedes, Rita C.. "The Neurological Clock is ticking: Advanced Computational exploration of Photoswitchable Molecules in Alzheimer's Treatment". Paper presented in XV iMed.ULisboa Postgraduate Students Meeting, 2024.
  10. Martinho, Nuno; Aniceto, Natália; Rita C. Guedes. "Cracking the Code of Antibiotics Through the Application of Multilabel Machine Learning". Paper presented in XV iMed.ULisboa Postgraduate Students Meeting, 2024.
  11. Filipe G. A. Estrada; Martinho, Nuno; Aniceto, Natália; Guedes, Rita C.. "A well-informed in silico approach to achieve significant improvements in the challenging battle against lung cancer". Paper presented in 4th Biophysics Festival, 2024.
  12. Dalila Mil-Homens; Laura Pereira; Rita F. Pires; José M. Andrade; Marta M. Alves; Gabriel Serafim; Martinho, Nuno; et al. "Biocompatible Engineered polyurea (PURE) dendrimers are a new hope against multidrug-resistant (MDR) bacteria". Paper presented in Microbiotec 23, 2023.
  13. Martinho, Nuno; Joaquim M. T. Marquês; Rodrigo F. M. Almeida; Vasco V. B. Bonifácio; Liana C Silva. "Polyurea (PURE) dendrimers as modulators of membrane permeability to enhance cisplatin delivery". Paper presented in InnovDelivery22, 2022.
  14. Martinho, Nuno; Mire Zloh; Rita F. Pires; Bonifácio, Vasco D. B.. "In silico characterization of PURE dendrimers-small molecules interactions". Paper presented in 11th International Dendrimer Symposium (IDS11), 2019.
  15. Martinho, Nuno; Liana C Silva; Helena Florindo; S. Brocchini; Mire Zloh; Teresa Barata. "Conformational behavior of poly(L-glutamic acid) dendrimers bearing different fluorophores and their interactions with membranes". Paper presented in APS UKPharmSci Conference, 2014.
  16. Martinho, Nuno; Liana C Silva; Helena Florindo; Brocchini, S.; Mire Zloh; Barata, Teresa. "In silico generation of a peptide dendrimer with different fluorophores and their interaction with a lipid bilayer model". Paper presented in EMBL-EBI/Wellcome Trust Workshop: Resources for Computational Drug Discovery, 2014.
  17. Martinho, Nuno; Philippe Maincent; Pinto Reis, Catarina; Gibaud, Stéphane. "Synthesis and characterization of S-nitroso-oligo-chitosan as NO-donor". Paper presented in Nano2013.pt, 2013.
  18. Martinho, Nuno; Barata, Teresa; Brocchini, S.; Silva, Liana C.; Helana Florindo; Mire Zloh. "Automated in silico approach to generate 3D poly(glutamic) acid dendrimers". Paper presented in 2nd EPSRC CIM in Emergent Macromolecular Therapies Annual Research Event, 2013.
  19. Martinho, Nuno; Brocchini, S.; Teresa Barata; Florindo, Helena; Silva, Liana C.; Vanessa Sainz; Mire Zloh. "A molecular Modelling Approach to the design and optimization of poly(glutamic acid) (PG) dendrimers as drug delivery vehicles". Paper presented in 2nd EPSRC CIM in emergen Macromolecular Therapies – Annual Research Event, 2013.
  20. Martinho, Nuno; Rosado, Catarina; Fernandes, Ana S.; Pinto Reis, Catarina. "Design of PLGA nanoparticles containing Azelaic Acid for Acne Treatment". Paper presented in Colloids and Nanomedicine, 2012.
  21. Martinho, Nuno; Rosado, Catarina; Pinto Reis, Catarina. "Application of new drug delivery systems in encapsulation of lipophilic drugs for transdermal use". Paper presented in III Congresso Nacional de Ciêncas Dermacosméticas, 2011.
  22. Martinho, Nuno; Pinto Reis, Catarina; Rosado, Catarina. "Design and permeation studies of Alginate multiparticulate systems for transdermal drug delivery". Paper presented in 12th Annual Meeting of Skin Forum, 2011.
  23. Martinho, Nuno; Rosado, Catarina; Silva, Catarina; Pinto Reis, Catarina. "Pre-formulation study: selection of a method for production of PLGA nanoparticles for later encapsulation of azelaic acid". Paper presented in Nano2011.pt, 2011.
  24. Martinho, Nuno; Rosado, Catarina; Pinto Reis, Catarina. "Development and optimization process of PLGA nanoparticles obtained by m-SESD method". Paper presented in Nano2011.pt, 2011.
  25. Martinho, Nuno; Rosado, Catarina; Silva, Catarina; Pinto Reis, Catarina. "Development of azelaic-acid PLGA nanoparticles by m-SESD method for topical treatment of acne". Paper presented in Nano2011.pt, 2011.
  26. Martinho, Nuno; Rosado, Catarina; Pinto Reis, Catarina. "Development of alginate beads and microparticles loaded with ibuprofen for transdermal delivery". Paper presented in IV Congresso Ibero-Americano de Ciências Farmacêuticas, 2011.
  27. Martinho, Nuno. "Avaliação comparativa da informação sobre medicamentos antidepressivos na intervenção em Cuidados Farmacêuticos". Paper presented in GICUF, 2009.
Journal article
  1. Aniceto, Natália; Martinho, Nuno; Rufino, Ismael; Guedes, Rita C. "LigExtract: Large-scale Automated Identification of Ligands from Protein Structures in the Protein Data Bank". Genomics, Proteomics & Bioinformatics (2025): https://doi.org/10.1093/gpbjnl/qzaf018.
    10.1093/gpbjnl/qzaf018
  2. Gosecki, Mateusz; Urbaniak, Malgorzata; Martinho, Nuno; Gosecka, Monika; Zloh, Mire. "Evaluation of Encapsulation Potential of Selected Star-Hyperbranched Polyglycidol Architectures: Predictive Molecular Dynamics Simulations and Experimental Validation". Molecules 28 21 (2023): 7308. http://dx.doi.org/10.3390/molecules28217308.
    10.3390/molecules28217308
  3. Aniceto, Natália; Albuquerque, Tânia S.; Bonifácio, Vasco D. B.; Guedes, Rita C.; Martinho, Nuno. "Using Machine Learning and Molecular Docking to Leverage Urease Inhibition Data for Virtual Screening". International Journal of Molecular Sciences 24 9 (2023): 8180. http://dx.doi.org/10.3390/ijms24098180.
    10.3390/ijms24098180
  4. Martinho, Nuno; Marquês, Joaquim M. T.; Todoriko, Iryna; Prieto, Manuel; de Almeida, Rodrigo F.M.; Silva, Liana C.. "Effect of Cisplatin and Its Cationic Analogues in the Phase Behavior and Permeability of Model Lipid Bilayers". Molecular Pharmaceutics (2023): http://dx.doi.org/10.1021/acs.molpharmaceut.2c00321.
    10.1021/acs.molpharmaceut.2c00321
  5. Aniceto, Natália; Bonifácio, Vasco D. B.; Guedes, Rita C.; Martinho, Nuno. "Exploring the Chemical Space of Urease Inhibitors to Extract Meaningful Trends and Drivers of Activity". Journal of Chemical Information and Modeling (2022): http://dx.doi.org/10.1021/acs.jcim.2c00150.
    10.1021/acs.jcim.2c00150
  6. Pinto, Sandra; Mil-Homens, Dalila; Pires, Rita; Alves, Marta M.; Serafim, Gabriel; Martinho, Nuno; Melo, Manuel; Fialho, Arsénio Mendes; Bonifácio, Vasco D.B.. "Core-shell polycationic polyurea pharmadendrimers: New-generation of sustainable broad-spectrum antibiotics and antifungals". Biomaterials Science (2022): http://dx.doi.org/10.1039/d2bm00679k.
    10.1039/d2bm00679k
  7. Martinho, Nuno; Pires, Rita F.; Zloh, Mire; Bonifácio, Vasco D. B.. "Intrinsic acetamide brush-off by polyurea biodendrimers". Journal of Materials Chemistry B 9 15 (2021): 3371-3376. http://dx.doi.org/10.1039/d1tb00105a.
    10.1039/d1tb00105a
  8. Martinho, Nuno; Santos, Tânia C. B.; Florindo, Helena F.; Silva, Liana C.. "Cisplatin-Membrane Interactions and Their Influence on Platinum Complexes Activity and Toxicity". Frontiers in Physiology 9 (2019): http://dx.doi.org/10.3389/fphys.2018.01898.
    10.3389/fphys.2018.01898
  9. Martinho, Nuno; Silva, Liana; Florindo, Helena; Brocchini, Steve; Zloh, Mire; Barata, Teresa. "Rational design of novel, fluorescent, tagged glutamic acid dendrimers with different terminal groups and in silico analysis of their properties". International Journal of Nanomedicine Volume 12 (2017): 7053-7073. http://dx.doi.org/10.2147/ijn.s135475.
    10.2147/ijn.s135475
  10. Martinho, Nuno; Silva, Liana C.; Florindo, Helena F.; Brocchini, Steve; Barata, Teresa; Zloh, Mire. "Practical computational toolkits for dendrimers and dendrons structure design". Journal of Computer-Aided Molecular Design 31 9 (2017): 817-827. http://dx.doi.org/10.1007/s10822-017-0041-6.
    10.1007/s10822-017-0041-6
  11. Moura, L. I. F.; Martinho, N.; Silva, L. C.; Barata, T. S.; Brocchini, S.; Florindo, H. F.; Zloh, M.. "Poly-glutamic dendrimer-based conjugates for cancer vaccination – a computational design for targeted delivery of antigens". Journal of Drug Targeting 25 9-10 (2017): 873-880. http://dx.doi.org/10.1080/1061186x.2017.1363213.
    10.1080/1061186x.2017.1363213
  12. Teresa Barata; Liane Moura; Martinho, Nuno (D51E-5772-FF5F); Helena F Florindo; Mire Zloh. "Computational design of a novel poly-glutamic dendrimer-based platform as an anticancer therapeutic approach". Febs Journal (2016):
  13. Shah, Shefaat Ullah; Martinho, Nuno; Socha, Marie; Pinto Reis, Catarina; Gibaud, Stéphane. "Synthesis and characterization ofS-nitrosoglutathione-oligosaccharide-chitosan as a nitric oxide donor". Expert Opinion on Drug Delivery 12 8 (2015): 1209-1223. http://dx.doi.org/10.1517/17425247.2015.1028916.
    10.1517/17425247.2015.1028916
  14. Martinho, Nuno; Florindo, Helena; Silva, Liana; Brocchini, Steve; Zloh, Mire; Barata, Teresa. "Molecular Modeling to Study Dendrimers for Biomedical Applications". Molecules 19 12 (2014): 20424-20467. http://dx.doi.org/10.3390/molecules191220424.
    10.3390/molecules191220424
  15. Catarina Pinto Reis; João Pinto Ferreira; Sara Candeias; Cátia Fernandes; Nuno Martinho; Natália Aniceto; António Silvério Cabrita; Isabel V. Figueiredo. "Ibuprofen Nanoparticles for Oral Delivery: Proof of Concept". Journal of Nanomedicine & Biotherapeutic Discovery 04 01 (2014): http://dx.doi.org/10.4172/2155-983x.1000119.
    10.4172/2155-983x.1000119
  16. Gomes, A.; Ascensão, L.; Rijo, P.; Baptista, M.; Candeias, S.; Martinho, N.; Fernandes, A.; Roberto, A.; Reis, C.. "Evaluation of a New Topical Treatment for Acne with Azelaic Acid-Loaded Nanoparticles". Microscopy and Microanalysis 19 S4 (2013): 59-60. http://dx.doi.org/10.1017/s1431927613000913.
    10.1017/s1431927613000913
  17. Reis, Catarina Pinto; Gomes, Ana; Rijo, Patrícia; Candeias, Sara; Pinto, Pedro; Baptista, Marina; Martinho, Nuno; Ascensão, Lia. "Development and Evaluation of a Novel Topical Treatment for Acne with Azelaic Acid-Loaded Nanoparticles". Microscopy and Microanalysis 19 05 (2013): 1141-1150. http://dx.doi.org/10.1017/s1431927613000536.
    10.1017/s1431927613000536
  18. Reis, Catarina Pinto; Martinho, Nuno; Rosado, Catarina; Fernandes, Ana S.; Roberto, Amílcar. "Design of polymeric nanoparticles and its applications as drug delivery systems for acne treatment". Drug Development and Industrial Pharmacy 40 3 (2013): 409-417. http://dx.doi.org/10.3109/03639045.2013.767826.
    10.3109/03639045.2013.767826
  19. Pinto Reis, Catarina; Silva, Catarina; Martinho, Nuno; Rosado, Catarina. "Drug carriers for oral delivery of peptides and proteins: accomplishments and future perspectives". Therapeutic Delivery 4 2 (2013): 251-265. http://dx.doi.org/10.4155/tde.12.143.
    10.4155/tde.12.143
  20. Martinho, Nuno; Rosado, Catarina; Reis, Catarina Pinto. "Influência de duas técnicas diferentes no tamanho e potencial zeta de nanopartículas de poli(D.L-láctico-co-glicólico)". (2013): http://hdl.handle.net/10437/3675.
  21. Martinho, Nuno; Rosado, Catarina; Pinto Reis, Catarina. "The influence of two different techniques on the particle size and zeta potencial of poly (D,L-Lactide-co-glycolide) nanoparticles". Journal Biomedical and Biopharmaceutical Research 8 2 (2011): 329-338. http://dx.doi.org/10.19277/bbr.8.2.21.
    10.19277/bbr.8.2.21
  22. Martinho, Nuno; Damgé, Christiane; Reis, Catarina Pinto. "Recent Advances in Drug Delivery Systems". Journal of Biomaterials and Nanobiotechnology 02 05 (2011): 510-526. http://dx.doi.org/10.4236/jbnb.2011.225062.
    10.4236/jbnb.2011.225062
Thesis / Dissertation
  1. Martinho, Nuno. "Fluorescent-based dendrimers as potential drug delivery carriers of cisplatin : from design and synthesis to platinum-membrane interactions". PhD, 2018. http://hdl.handle.net/10451/35238.

Other

Software
  1. Aniceto, Natália; Martinho, Nuno; Guedes, Rita C.. "LigExtract: Automated Ligand Indentification and Extraction from PDB Structures". https://github.com/comp-medchem/LigExtract. 2024.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025 Insights towards cutinase stabilization: Modelling interactions with triazine-scaffolded synthetic affinity ligands 5th Biophysics Festival
2024 Revolutionizing Alzheimer's Treatment: Harnessing Photoswitchable Molecules through cutting-edge in Silico methods in Neuroscience 9th Biophysics Festival
(Covilhã, Portugal)
2024 Targeting the circadian clock and Alzheimer's disease: a structure-based strategy to discover orexin receptor photoswitches. Biophysics Festival – 4th Meeting of Young Biophysicists
Faculty of Sciences of University of Beira Interior (Covilhã, Portugal)
2024 Tackling lung cancer with novel protein targets: an in silico approach 15th iMed.ULisboa Postgraduate Students Meeting
Faculdade de Farmácia da Universidade de Lisboa (Lisboa, Portugal)
2024 Using Artificial Intelligence to Uncover Molecular Patterns of Urease Inhibition EuChemS Chemistry in Life Sciences Young Investigator Workshop
(Galway, Ireland)
2023/09 Journey to the Chemical Frontier of Urease Inhibition: molecular design guided by machine learning I International meeting: Molecules 4 Life
2023 Nature-inspired anticancer polycationic core-shell dendrimers I International meeting: Molecules 4 Life
2022 Engineered polyurea (PURE) dendrimers are a potential alternative to conventional antibiotics Asiapacificbiofilms
2022 Dendrimer nanotherapeutics: A novel anticancer task force 3rd International Conference on Nanomaterials Applied to Life Sciences
2019/07/29 Insights from molecular modeling and dynamics into dendrimers as drug delivery carriers Seminar at itqb
(Portugal)
2012 Design of azelaic-acid loaded PLGA nanoparticles for topical delivery XX BRG Annual International Conference on Bioencapsulation
(Canada)
2011/11/14 Citicoline drug penetration across the blood barrier for treatment of mental diseases Angelini University Award
(Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2024 - Current Exploring the Intersection of Artificial Intelligence in Understanding Alzheimer's Disease: The Role of the Circadian Clock and Orexin Receptors
Co-supervisor
 Ciências Farmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023 ChemSlotProtein: Expanding the druggable universe to unlock chemists´creativity
(Thesis) Arguer
 Ismael Rufino de Carvalho (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023 Development of a new integrated system for the treatment of chronic kidney disease: Synergetic combination of a nano-drug delivery system and membrane technology
(Thesis) Main arguer
 Pedro Rodrigues Nunes Paulo de Almeida (Master)
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
2022/12/28 Analysis of PI(4,5)P2 organization at the plasma membrane of living cells through a combinations of FRET and FRAP Pedro Bulcão (Master)
2022 Avaliação in vitro do potencial terapêutico de novos compostos contra a tuberculose INÊS ALEXANDRA BOTELHO PORTO CUNHA E SILVA ANTUNES (Other)
2021/11 Towards nanostructured membranes for the artificial kidney
(Thesis) Main arguer
 Madalena Pereira Bonifácio Lopes (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019 Advanced dendrimers for capture and storage of sustainable energy
Thesis Member
 Rita Figueiredo Pires (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Association member

Society Organization name Role
2011 - 2012 REFlexus magazine Contributer to editorial team

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2025 - Current Inteligência Artificial e Análise de Dados na Descoberta de Medicamentos - Invited Lecturer (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2024 - Current Seminar: Introdução ao desenho de ligandos auxiliado por métodos computacionais
2023 - Current Seminar: From lab to jab: basic concepts of nano drug delivery systems
2025 - 2025 Seminar: Introdução ao desenho de ligandos auxiliado por métodos computacionais Universidade de Lisboa Instituto Superior Técnico, Portugal
2025 - 2025 Seminar: Molecules in Motion: Computational Biophysics in Drug Discovery Universidade de Lisboa Faculdade de Farmácia, Portugal
2024 - 2024 Seminar: From lab to jab: basic concepts of nano drug delivery systems
2024 - 2024 Inteligência Artificial e Análise de Dados na Descoberta de Medicamentos - Invited Lecturer Inteligência Artificial e Análise de Dados na Descoberta de Medicamentos (Mestrado integrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/01/26 - 2022/01/26 Seminar: From lab to jab: basic concepts of nano drug delivery systems Biologia Molecular (Mestrado integrado) Universidade de Lisboa Instituto Superior Técnico, Portugal

Mentoring / Tutoring

Topic Student name
2024 - 2024 In Silico Discovery and Optimization of Small Molecules Targeting Neurodegenerative Diseases Diana Assis
2024 - 2024 Exploring the Intersection of Artificial Intelligence in Understanding Alzheimer's Disease: The Role of the Circadian Clock and Orexin Receptors Ana Gonçalves
2022 - 2023 Targeting cytoplasmic lipid droplets for therapeutic and imaging applications Elodie Delavictoire
2022/09 - 2022/10 Virtual Screening of polyurea dendrimers as metalloenzyme inhibitors Ana Clara Rodrigues
2022 - 2022 Green synthesis and in vitro performance of novel urease inhibitors Tânia Albuquerque
2022 - 2022 Manufacture of biopolymers via mechanochemistry Marta Brandão
2021 - 2022 Design, synthesis and in vitro test of novel urease inhibitors Inês Azevedo
2019 - 2020 Insights into the killing mechanism of biomimetic antimicrobial polymers using MD simulations Gabriel Serafim

Other jury / evaluation

Activity description Institution / Organization
2025 - 2025 Jury for the 5th Biophysics Festival
Distinctions

Award

2013 Merit Scholarship
2013 Student Merit
Ordem dos Farmaceuticos, Portugal

Other distinction

2022 Review Editor of Technological and Methodological Advances in Drug Delivery
2020 Guest Editor of Polymers (MDPI) for issue on Polyureas
Multidisciplinary Digital Publishing Institute AG, Switzerland
2012 Merit Scholarship
2012 ERASMUS scholarship
European Commission, Belgium
2011 Merit Scholarship
2009 Merit Scholarship