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Filipe Daniel Ramos Carvalho. Concluiu o(a) Doutoramento em PhD Degree in Biotechnology and Biosciences em 2015 pelo(a) Universidade de Lisboa Instituto Superior Técnico, Mestrado em Mestrado em biotecnologia em 2010 pelo(a) Universidade de Lisboa Instituto Superior Técnico e Licenciatura em Engenharia biotecnológica em 2008 pelo(a) Universidade Lusófona de Humanidades e Tecnologias. É Pós-doutorado no(a) Universidade de Lisboa Instituto Superior Técnico. Publicou 11 artigos em revistas especializadas. Possui 1 capítulo(s) de livros e 3 livro(s). Atua na(s) área(s) de Ciências da Engenharia e Tecnologias com ênfase em Biotecnologia Industrial com ênfase em Biocatálise. Nas suas atividades profissionais interagiu com 23 colaborador(es) em coautorias de trabalhos científicos. No seu currículo Ciência Vitae os termos mais frequentes na contextualização da produção científica, tecnológica e artístico-cultural são: Bioprocess engineering; Biocatalyst immobilization; Miniaturization; Scale-up; Multi-step bioconversion; Marine biocatalysts; .
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Identification

Personal identification

Full name
Filipe Daniel Ramos Carvalho

Citation names

  • Carvalho, Filipe

Author identifiers

Ciência ID
D41F-388A-A4DE
ORCID iD
0000-0002-8381-9163

Websites

Knowledge fields

  • Engineering and Technology - Industrial Biotechnology - Biocatalysis

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Portuguese (Mother tongue)
Education
Degree Classification
2015/12/07
Concluded
 PhD Degree in Biotechnology and Biosciences (Doutoramento)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"Development of enzyme microreactors and application in biocatalysis" (THESIS/DISSERTATION)
 Pass with Distinction
2010
Concluded
 Mestrado em biotecnologia (Mestrado)
Universidade de Lisboa Instituto Superior Técnico, Portugal
"Miniature systems as platforms for the characterization of a multi-step bioconversion in silicone media" (THESIS/DISSERTATION)
 17
2008
Concluded
 Engenharia biotecnológica (Licenciatura)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
"Produção de 4-androsteno-3,17-diona (AD) em pequena escala a partir de sitosterol utilizando células de Mycobacterium sp. NRRL B-3805 imobilizadas " (THESIS/DISSERTATION)
 14
Affiliation

Science

Category
Host institution 		Employer
2017/03/01 - 2019/12/31 Postdoc (Research) Universidade de Lisboa Instituto Superior Técnico, Portugal
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
2008/01/01 - 2008/10/01 Research Trainee (Research) Universidade de Lisboa Instituto Superior Técnico, Portugal
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal
Projects

Grant

Designation Funders
2019/06/01 - 2019/12/31 IBB2019 – 1081P.00892.1.01 UID/BIO/04565/2019
IBB2019 – 1081P.00892.1.01, UID/BIO/04565/2019
Post-doc Fellow
iBB-Institute for Bioengineering and Biosciences; Department of Bioengineering of Instituto Superior Técnico, Universidade de Lisboa , Portugal
Fundação para a Ciência e a Tecnologia
2019/06 - 2019/12 IBB2019 ¿ 1081P.00892.1.01 UID/BIO/04565/2019
IBB2019 1081P.00892.1.01, UID/BIO/04565/2019
 Fundação para a Ciência e a Tecnologia
2017/03/01 - 2017/12/31 IBB2015/2017, RD0453 UID/BIO/04565/2013
IBB2015/2017, RD0453 UID/BIO/04565/2013
Post-doc Fellow
iBB-Institute for Bioengineering and Biosciences; Department of Bioengineering of Instituto Superior Técnico, Universidade de Lisboa , Portugal
Fundação para a Ciência e a Tecnologia
2017/03 - 2017/12 IBB2015/2017, RD0453 UID/BIO/04565/2013
IBB2015/2017, RD0453 UID/BIO/04565/2013
 Fundação para a Ciência e a Tecnologia

Contract

Designation Funders
2021/01/01 - 2025/12/31 Institute for Health and Bioeconomy
LA/P/0140/2020
10.54499/LA/P/0140/2020
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal

Universidade Nova de Lisboa, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

INESC Microsistemas e Nanotecnologias, Portugal

Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2019/01/01 - 2023/12/31 Applied Molecular Biosciences Unit
UIDP/04378/2020
10.54499/UIDP/04378/2020
UIDB/04378/2020
10.54499/UIDB/04378/2020
Universidade de Lisboa Instituto de Bioengenharia e Biociências, Portugal

Universidade Nova de Lisboa, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade do Porto, Portugal

Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal

INESC Microsistemas e Nanotecnologias, Portugal

Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/01/01 - 2019/03/31 Industrial Applications of Marine Enzymes: Innovative screening and expression platforms to discover and use the functional protein diversity from the sea
info:eu-repo/grantAgreement/EC/Horizon 2020 Framework Programme/634486/EU
Post-doc Fellow
European Commission
2014/04/01 - 2014/09/28 European network for innovative microbioreactor applications in bioprocess development
info:eu-repo/grantAgreement/EC/SEVENTH FRAMEWORK PROGRAMME/608104/EU
Researcher
European Commission

Other

Designation Funders
2010/01/01 - 2011/12/31 Bilateral Portugal-Slovenia Cooperation Program
xxxxx
Researcher
iBB-Institute for Bioengineering and Biosciences; Department of Bioengineering of Instituto Superior Técnico, Universidade de Lisboa , Portugal

Faculty of Chemistry and Chemical Technology, University of Ljubljana, Slovenia, Slovenia
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Carvalho, F.; Fernandes, P.. "Enzymes applied in sweeteners production". 217-243. 2024.
  2. FERNANDES, PEDRO; Carvalho, Filipe. "Microbial enzymes used in food industry". In Biotechnology of Microbial Enzymes; Production, Biocatalysis and industrial applications, edited by Goutam Brahmachari, 445-479. Academic Press, 2023.
    Published
  3. Fernandes, P.; Carvalho, F.. "Microbial enzymes used in food industry". 445-496. 2023.
  4. Carvalho, Filipe; FERNANDES, PEDRO. "Recent developments in enzyme immobilization for food production". In Value-Addition in Food Products and Processing Through Enzyme Technology, 453-466. Elsevier, 2022.
    10.1016/b978-0-323-89929-1.00017-2
  5. Carvalho, F.; Fernandes, P.. "Recent developments in enzyme immobilization for food production". 453-466. 2021.
  6. Carvalho, Filipe; Fernandes, Pedro. "Enzymes in Sweeteners Production". In Energy, Environment, and Sustainability, 151-179. Springer Singapore, 2018.
    10.1007/978-981-13-3263-0_9
  7. Fernandes, P.; Carvalho, F.. "Microbial Enzymes for the Food Industry". In Biotechnology of Microbial Enzymes Production, Biocatalysis and Industrial Applications. Elsevier Inc., 2017.
    10.1016/B978-0-12-803725-6.00019-4
  8. Fernandes, P.; Carvalho, F.. "Enzymes in Food Processing". In Agro-Industrial Wastes as Feedstock for Enzyme Production : Apply and Exploit the Emerging and Valuable Use Options of Waste Biomass. Elsevier Science Publishing Co Inc, 2016.
    Published • 10.1016/B978-0-12-802392-1.00008-3
  9. Fernandes, P.; Marques, M.P.C.; Carvalho, F.; de Carvalho, C.C.C.R.. "Organic solvents: properties, toxicity and industrial effects". In Organic-solvent tolerant Gram-positive bacteria: Applications and mechanisms of tolerance. Nova Science Publishers, Inc, 2011.
Conference poster
  1. Carvalho, Filipe; de Carvalho, C.C.C.R.; Carlos Rodrigues; Ricardo Pereira; Joaquim M.S. Cabral; Pedro Fernandes. "Culturomics approaches for finding marine biocatalysts". Paper presented in 12th Symposium of the European Society of Biochemical Engineering Sciences (ESBES 2018), 2018.
  2. Carvalho, Filipe; Marques, Marco P. C. ; Pedro Fernandes. "Immobilization of inulinase inside silica microchannels". Paper presented in 9th International Conference on Protein Stabilisation, 2012.
  3. Carvalho, Filipe; Marques, Marco P. C. ; Gabriel Monteiro; Joaquim M.S. Cabral; Fernandes, Pedro. "Maintenance of catalytic activity in complex steroid bioconversion". Paper presented in XVI Congress of Biochemistry, 2008.
  4. Carvalho, Filipe; Pedro Fernandes; Stefano Cattorini; Marques, Marco P. C. ; Susana Bernardino; de Carvalho, C.C.C.R.; Luis Fonseca; Joaquim M.S. Cabral. "A multipurpose hydrogel system for biocatalyst immobilization". Paper presented in 10th International Chemical and Biological Engineering Conference - CHEMPOR 2008, 2008.
  5. Carvalho, Filipe; Marques, Marco P. C. ; Fernandes, Pedro; Joaquim M.S. Cabral. "Multi-step biotransformations throughout scales". Paper presented in Seventh European Symposium on Biochemical Engineering Science, 2008.
  6. Carvalho, Filipe; Pedro Fernandes; Marques, Marco P. C. ; Joaquim M.S. Cabral. "A simple method for biocatalyst immobilization using PVA based hydrogel particles". Paper presented in seventh European Symposium on Biochemical Engineering Science, 2008.
  7. Carvalho, Filipe; Marques, Marco P. C. ; Joaquim M.S. Cabral; Pedro Fernandes. "On the use of log Poctanol as criterion for solvent selection in bioconversions". Paper presented in MICRO’07 BIOTEC’07-XXXIII, 2007.
Journal article
  1. Gruber, P.; Carvalho, F.; Marques, M.P.C.; O'Sullivan, B.; Subrizi, F.; Dobrijevic, D.; Ward, J.; et al. "Enzymatic synthesis of chiral amino-alcohols by coupling transketolase and transaminase-catalyzed reactions in a cascading continuous-flow microreactor system". Biotechnology and Bioengineering (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85033397153&partnerID=MN8TOARS.
    10.1002/bit.26470
  2. Carvalho, F.; Marques, M.P.C.; Fernandes, P.. "Sucrose hydrolysis in a bespoke capillary wall-coated microreactor". Catalysts 7 2 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85013042436&partnerID=MN8TOARS.
    10.3390/catal7020042
  3. Carvalho, F.; Paradiso, P.; Saramago, B.; Ferraria, A.M.; Do Rego, A.M.B.; Fernandes, P.. "An integrated approach for the detailed characterization of an immobilized enzyme". Journal of Molecular Catalysis B: Enzymatic 125 (2016): 64-74. http://www.scopus.com/inward/record.url?eid=2-s2.0-84955263791&partnerID=MN8TOARS.
    10.1016/j.molcatb.2016.01.001
  4. Carvalho, F.; Fernandes, P.. "Packed bed enzyme microreactor: Application in sucrose hydrolysis as proof-of-concept". Biochemical Engineering Journal (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84928817262&partnerID=MN8TOARS.
    10.1016/j.bej.2015.04.023
  5. Carvalho, Filipe. "A microscopic perspective of a microreactor". Microscopy and Microanalysis (2013):
    10.1017/S1431927613000780
  6. Fernandes, P.; Carvalho, F.; Marques, M.P.C.. "Miniaturization in biotechnology: Speeding up the development of bioprocesses". Recent Patents on Biotechnology 5 3 (2011): 160-173. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054124219&partnerID=MN8TOARS.
    10.2174/187220811797579105
  7. Marques, M.P.C.; Carvalho, F.; de Carvalho, C.C.C.R.; Cabral, J.M.S.; Fernandes, P.. "Steroid bioconversion: Towards green processes". Food and Bioproducts Processing 88 1 (2010): 12-20. http://www.scopus.com/inward/record.url?eid=2-s2.0-77949271542&partnerID=MN8TOARS.
    10.1016/j.fbp.2010.01.009
  8. Cattorini, S.; Marques, M.P.C.; Carvalho, F.; Chheub, V.; Cabral, J.M.S.; Fernandes, P.. "Lentikat®-based biocatalysts: Effective tools for inulin hydrolysis". Chemical and Biochemical Engineering Quarterly 23 4 (2009): 429-434. http://www.scopus.com/inward/record.url?eid=2-s2.0-74549204570&partnerID=MN8TOARS.
  9. Fernandes, P.; Marques, M.P.C.; Carvalho, F.; Cabral, J.M.S.. "A simple method for biocatalyst immobilization using PVA-based hydrogel particles". Journal of Chemical Technology and Biotechnology 84 4 (2009): 561-564. http://www.scopus.com/inward/record.url?eid=2-s2.0-67449116849&partnerID=MN8TOARS.
    10.1002/jctb.2080
  10. Carvalho, F.; Marques, M.P.C.; Carvalho, C.C.C.R.d.; Cabral, J.M.S.; Fernandes, P.. "Sitosterol bioconversion with resting cells in liquid polymer based systems". Bioresource Technology 100 17 (2009): 4050-4053. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349117272&partnerID=MN8TOARS.
    10.1016/j.biortech.2009.03.044
  11. Marques, M.P.C.; Carvalho, F.; Magalhães, S.; Cabral, J.M.S.; Fernandes, P.. "Screening for suitable solvents as substrate carriers for the microbial side-chain cleavage of sitosterol using microtitre plates". Process Biochemistry 44 5 (2009): 556-561. http://www.scopus.com/inward/record.url?eid=2-s2.0-64049116045&partnerID=MN8TOARS.
    10.1016/j.procbio.2009.01.014

Other

Other output
  1. Cover Image, Volume 115, Number 3, March 2018; Biotechnology and Bioengineering 115(3):i-i; DOI: 10.1002/bit.26413. 2018. Carvalho, Filipe; Gruber, Pia; Marques, Marco P. C..
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2014/09 An integrated approach for the thorough characterization of an enzymatic microreactor 10th european Symposium on Biochemical Engineering Sciences
ESBES (Lille)
2013/12 Towards a rational approach for enzyme immobilization in a microreactor framework Micro Biotec´13 Portuguese Congress of Microbiology and Biotechnology
(Aveiro, Portugal)
2013/09 A microscopic perspective of a microreactor Microscopy: A tool for the advancement of Science
Congress of the Portuguese Society for Microscopy 2012 (Lisbon, Portugal)
2013/05 Continuous sucrose hydrolysis in microchannel reactors Implementation of Microreactor Technology in Biotechnology; 2nd International Conference
(Cavtat, Croatia)
2010/10 Bringing miniaturization to bioconversion systems Laboratório Associado IBB - Institute for Biotechnology and Bioengineering, 2nd Scientific Meeting
(braga, Portugal)
2009/07 The sunny side of mycobacteria Congress of the European Society of Mycobacteriology - ESM 2009
(Porto, Portugal)
2009/05 Carbohydrate hydrolysis with commercial inulinase entrapped in PVA-based beads Achema 2009
(Frankfurt, Germany)
2009/05 Steroids bioconversion: towards green processes 2009 American Control Conference
(Frankfurt, Germany)
2009/01 A dual purpose immobilized biocatalyst for inulin and sucrose hydrolysis Carbohydrates as Organic Raw Materials V
(Lisboa, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2020/02/01 - 2020/11/15 Developing bioprocesses using marine lipases
Co-supervisor of Miguel Alexandre Ricardo da Cunha
 Engenharia Biológica (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2019/09/15 - 2020/11/15 Towards the optimization of a heterogeneous biocatalyst: Endoinulinase to produce high fructose syrups
Co-supervisor of Luís António da Silva Duarte
 Master Programme in Biotechnology (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2019/06/01 - 2020/06/30 1st iBB workshop and periodic scientific seminars- organizing committe member (2019/10/29)
Workshop (Member of the Organising Committee)
 iBB-Institute for Bioengineering and Biosciences; Department of Bioengineering of Instituto Superior Técnico, Universidade de Lisboa , Portugal
2012/05/02 - 2012/05/04 Member of the organization committee of the 9th International Conference on Protein Stabilisation (2012/05/02 - 2012/05/04)
Congress (Member of the Organising Committee)
 Universidade de Lisboa Instituto Superior Técnico, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2019/11 Enzyme immobilization in porous micro beads in microfluidics for continuous production of L-DOPA and dopamine
(Thesis) Main arguer
 Cristiana Maria Filipe Domingues (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018/11 "Exploiting the Biocatalytic Potential of Marine Bacteria"
(Thesis) Main arguer
 Daniela Dias Silva (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018/11 "Protein Hydrolysis - Study of the agglomeration, degree of hydrolysis and peptide pattern"
(Thesis) Main arguer
 Tatiana Rodrigues Almeida (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2020/02/01 - 2021/01/31 Industrial Microbiology; Microbiology; Bioprocess Engineering Principles; Introduction to Bioreactors; Enzymatic Engineering Biotecnologia (Licenciatura) Universidade Lusófona de Humanidades e Tecnologias, Portugal
Distinctions

Title

2015 PhD completed with distinction
iBB-Institute for Bioengineering and Biosciences; Department of Bioengineering of Instituto Superior Técnico, Universidade de Lisboa , Portugal