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Susana Lopes da Silva graduated in Medicine in 1997 (Faculdade de Medicina, Universidade de Lisboa - FMUL) and completed her resident training in Allergy and Clinical Immunology in 2005 in Hospital de Santa Maria, Lisboa.. She spent 3 months working in Hospital Val d´Hebron in 2004 dedicated to Primary Immunodeficiencies and there she completed her Master Thesis on Regulatory T cells in patients with Common Variable Immunodeficiency. Since then, she has been dedicating her interest to children and adults with Inborn Errors of Immunity (IEI). She is currently the coordinator of Centro de Imunodeficiências Primárias, Lisboa and local Vice -Representative of ERN RITA. She joined AESousa Lab Team in IMM in 2007 and she obtained a PhD Degree on Clinical Immunology in 2016 (FMUL) with a thesis focused on the "Long term strategies to preserve naive compartment upon thymectomy in early childhood". This background, and the fact that she leads the clinical Team dedicated to IEI in Adulthood in Hospital de Santa Maria contributed to set the scenario for continued Research in the field. She has also been involved in teaching at FMUL and is currently Co-regent of the optional discipline of Clinical Immunology of the 4th and 5th year of the Degree in Medicine. She has supervised clinical training in Allergy / IEI for medical residents from different Hospitals.
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Identification

Personal identification

Full name
Susana Lopes da Silva

Citation names

  • Silva, Susana L
  • Susana Silva
  • Susana L Silva
  • Susana Lopes-da-Silva

Author identifiers

Ciência ID
D216-A049-12EF
ORCID iD
0000-0003-3943-1185

Telephones

Mobile phone
  • 912529394 (Personal)

Addresses

  • Avenida Prof Egas Moniz, 1649-¿028, Lisboa, Lisboa, Portugal (Professional)

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Immunology
  • Medical and Health Sciences - Clinical Medicine - Allergy
  • Medical and Health Sciences - Clinical Medicine - Other Clinical Medicine Subjects
  • Medical and Health Sciences - Basic Medicine - Human Genetics

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Advanced (C1)
French Elementary (A2) Intermediate (B1) Intermediate (B1) Intermediate (B1) Elementary (A2)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Intermediate (B1) Elementary (A2)
Education
Degree Classification
2015/05 - 2020
Concluded
 Grau de Consultor - Carreira Médica - Imunoalergologia (Outros)
Centro Hospitalar Universitário Lisboa Norte EPE, Portugal
2012 - 2016/11/21
Concluded
 Programa Doutoral do Centro Académico de Medicina de Lisboa (ramo de Medicina; ramo de Ciências Biomédicas; ramo de Ciências e Tecnologias da Saúde) (Doutoramento)
Universidade de Lisboa Faculdade de Medicina, Portugal
"Living without thymus: lessons from adults thymectomized in early infancy" (THESIS/DISSERTATION)
 Aprovada com Louvor e Distinção
2013 - 2013
Concluded
 Clinical Scholars Research Training Certificate Program (I) (Pós-Graduação)
Harvard Medical School, United States
2003 - 2007
Concluded
 Imunologia Clínica (Mestrado)
Universidade de Lisboa Faculdade de Medicina, Portugal
"Autoimmunidade e céulas reguladoras T CD4CD25high na Imunodeficiência Comum Variável" (THESIS/DISSERTATION)
 20 / 20 values
2000 - 2005
Concluded
 Especialidade de Imunoalergologia (Título de especialista)
Centro Hospitalar Universitário Lisboa Norte EPE, Portugal
 19,8 / 20 valores
1991 - 1997
Concluded
 Medicina (Licenciatura)
Universidade de Lisboa Faculdade de Medicina, Portugal
 17 / 20
Affiliation

Science

Category
Host institution 		Employer
2017/01 - Current Postdoc (Research) Instituto de Medicina Molecular João Lobo Antunes, Portugal
2007 - 2017 Researcher (Research) Instituto de Medicina Molecular João Lobo Antunes, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2017/01 - Current Invited Assistant Professor (University Teacher) Universidade de Lisboa Faculdade de Medicina, Portugal
2008 - 2016 Assistant (University Teacher) Universidade de Lisboa Faculdade de Medicina, Portugal
1997 - 2003 Invited Assistant (University Teacher) Universidade de Lisboa Faculdade de Medicina, Portugal

Other Careers

Category
Host institution 		Employer
2015/05 - Current Assistente graduado (Médica) Centro Hospitalar Universitário Lisboa Norte EPE, Portugal
CHULN-Servuiço de Imunoalergologia, Portugal
2005 - 2015 Assistente (Médica) Centro Hospitalar Universitário Lisboa Norte EPE, Portugal
CHULN-Servuiço de Imunoalergologia, Portugal
2004/01/01 - 2004/04/30 Interno (Médica) Centro Sociosanitario de la Vall d'Hebron de Barcelona, Spain

Positions / Appointments

Category
Host institution 		Employer
2007 - Current Co-Coordinator Centro de Imunodeficiências Primárias, Portugal
Projects

Grant

Designation Funders
2020/09 - Current Gut Permeability in Children and Adults with Systemic Lupus Erythematosus
Lupus
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Fundação Amélia de Mello
Concluded
2013/06/01 - 2015/05/31 Bee Venom as a tool to expand the human regulatory T-cell compartment
PTDC/DTP-PIC/0508/2012
Researcher
2009/01/02 - 2011/12/31 Long-term impact of thymectomy performed in early infancy
PIC/IC/83068/2007
Researcher
Concluded

Contract

Designation Funders
2022 - Current Modulação da resposta humoral por células T auxiliares foliculares humanas
2022.04903.PTDC
Researcher
2021/03/28 - Current Targeting naïve CD4 T cells to avoid human immunodeficiency
PTDC/MED-IMU/0938/2020
Researcher
2021/01/01 - 2025/12/31 Instituto de Medicina Molecular João Lobo Antunes
LA/P/0082/2020
10.54499/LA/P/0082/2020
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2019/01/01 - 2019/12/31 Instituto de Medicina Molecular - IMM
UID/BIM/50005/2019
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2015/01/01 - 2017/12/31 Targeting Germinal Centre Dysregulation in Allergy
HMSP-ICT/0034/2013
Researcher
Concluded

Other

Designation Funders
2013/01/01 - 2015/12/31 Infecções crónicas por Candida albicans e defeitos intrínsecos do sistema imunitário: optimização dos cuidados de saúde através do diagnóstico de imunodeficiências primárias.
xxxxxx
Principal investigator
Outputs

Publications

Book chapter
  1. Silva, Susana L. "Misturas de alergénios: sim ou não?". In Manual Imunoterapia com alergénios., 121-124. Portugal: Bial Aristegui, 2015.
    Published
  2. Silva, Susana L. "Imunodeficiências primárias". In Fundamentos de Imunoalergologia. Da Epidemiologia ao Tratamento., 271-284. Portugal: Lidel, 2011.
    Published
  3. Silva, Susana L. "Aspergilose Bronco Pulmonar Alérgica". In Livro de Homenagem a Antero da Palma Carlos, 189-200. Portugal: GlaxoSmithKline,, 2004.
    Published
  4. Silva, Susana L. "Broncodilatadores". In A Criança Asmática no Mundo da Alergia, 161-172. Portugal: Euromédice, 2003.
    Published
Conference poster
  1. Santos, Diana F; Paulo-Pedro, Margarida; Moleirinho, Beatriz; Gomes, Andre Miguel Carapinha; Afonso RM Almeida; Susana Lopes-da-Silva; Ana E Sousa. "Thymus Transplantation in FOXN1 Deficiency: 17 years Follow-up revealed Lack of Naïve T-Cell Sustainability despite Clinical Success". Paper presented in ESID 2024 Human inborn errors of immunity: an expanding universe, 2024.
  2. Paulo-Pedro, Margarida; Moleirinho, Beatriz; Santos, Diana F; Gomes, Andre Miguel Carapinha; Susana Lopes-da-Silva; Afonso RM Almeida; Ana E Sousa. "The T-Cell Compartment 17 Years Post Allogeneic Thymus Transplantation in a Patient with FOXN1 Mutation". Paper presented in ThymE 24: T Cell & Thymus Biology, 2024.
  3. Paulo-Pedro, Margarida; Moleirinho, Beatriz; Santos, Diana F; Gomes, Andre Miguel Carapinha; Susana Lopes-da-Silva; Raposo, AASF; Afonso RM Almeida; Ana E Sousa. "The T-cell compartment at a single-cell level 17 years post thymus transplantation in a patient with FOXN1 mutation". Paper presented in SPI’49 XLIX Annual Meeting Portuguese Society for Immunology, 2024.
  4. Moleirinho, Beatriz; Paulo-Pedro, Margarida; Santos, Diana F; Gomes, Andre Miguel Carapinha; Susana Lopes-da-Silva; Afonso RM Almeida; Ana E Sousa. "Thymectomy in early childhood: probing 30 years of CD4 T-Cell resilience". Paper presented in SPI’49 XLIX Annual Meeting Portuguese Society for Immunology, 2024.
  5. Moleirinho, Beatriz; Paulo-Pedro, Margarida; Diana F Santos; Gomes, Andre Miguel Carapinha; Susana Lopes-da-Silva; Afonso RM Almeida; Ana E Sousa. "Living without a Thymus: Impact on CD4 T cell compartment". Paper presented in 3rd Symposium of the National Research Infrastructure for Genome Sequencing and Analysis, 2023.
  6. Paulo-Pedro, Margarida; Moleirinho, Beatriz; Santos, Diana F; Gomes, Andre Miguel Carapinha; Susana Lopes-da-Silva; Afonso RM Almeida; Ana E Sousa. "Once upon Athymia: the T-cell pool a patient with FOXN1 mutation, 17 years post-thymic transplant". Paper presented in 3rd Symposium of the National Research Infrastructure for Genome Sequencing and Analysis, 2023.
  7. Raposo, AASF; Rosmaninho, Pedro; PAÇO, SUSANA; Ângelo-Dias, M; Godinho-Santos, Ana; Nunes-Cabaço, Helena; Tokunaga-Mizoro, Yumie; et al. "Differential Binding in human thymic regulatory T cells refine whole-genome analyses of complex immune diseases". Paper presented in XLVIII Annual Meeting of the Portuguese Society for Immunology, 2023.
Journal article
  1. Paulo-Pedro, Margarida; Moleirinho, Beatriz; Santos, Diana F.; Gomes, André M.C.; Rei, Margarida; Almeida, Afonso R.M.; Marques, José G.; Silva, Susana L.; Sousa, Ana E.. "Adulthood outcomes of thymic transplantation in a case of congenital athymia due to FOXN1 mutation". Journal of Allergy and Clinical Immunology (2025): https://doi.org/10.1016/j.jaci.2025.02.006.
    10.1016/j.jaci.2025.02.006
  2. Raposo, Alexandre A. S. F.; Rosmaninho, Pedro; Silva, Susana L.; Paço, Susana; Brazão, Maria E.; Godinho-Santos, Ana; Tokunaga-Mizoro, Yumie; et al. "Decoding mutational hotspots in human disease through the gene modules governing thymic regulatory T cells". Frontiers in Immunology 15 (2024): https://doi.org/10.3389/fimmu.2024.1458581.
    10.3389/fimmu.2024.1458581
  3. Van Coillie, Samya; Prévot, Johan; Sánchez-Ramón, Silvia; Lowe, David M.; Borg, Michael; Autran, Brigitte; Segundo, Gesmar; et al. "Charting a course for global progress in PIDs by 2030 — proceedings from the IPOPI global multi-stakeholders’ summit (September 2023)". Frontiers in Immunology 15 (2024): http://dx.doi.org/10.3389/fimmu.2024.1430678.
    10.3389/fimmu.2024.1430678
  4. Sofia Cosme Ferreira; Josefina Vieira; Maria Inês T. Silva; Sara P. Silva; Joana Caiado; Elisa Pedro; Susana L. Silva. "Terapêutica Substitutiva com Imunoglobulina G Polivalente: Particularidades de um Coorte Português". Acta Médica Portuguesa (2024): https://doi.org/10.20344/amp.20677.
    10.20344/amp.20677
  5. Rebelo, Sandra D; Ferreira, Tiago; Pacheco, Teresa; Silva, Susana L; Tornada, Ana. "Good Syndrome in a Young Woman: An Unusual Presentation". Cureus (2024): http://dx.doi.org/10.7759/cureus.52705.
    10.7759/cureus.52705
  6. Costa, Célia; Esteves Caldeira, Leonor; Paulino, Marisa; Santos, Diana F.; Silva, Susana L.. "Atopy and Response to Omalizumab Treatment in Chronic Spontaneous Urticaria". International Archives of Allergy and Immunology (2023): 1-7. http://dx.doi.org/10.1159/000535414.
    Accepted • 10.1159/000535414
  7. Torres-Valle, Alba; Aragon, Larraitz; Silva, Susana L.; Serrano, Cristina; Marcos, Miguel; Melero, Josefa; Bonroy, Carolien; et al. "In-depth blood immune profiling of Good syndrome patients". Frontiers in Immunology 14 (2023): http://dx.doi.org/10.3389/fimmu.2023.1285088.
    10.3389/fimmu.2023.1285088
  8. Sousa e Silva, R.; Pereira da Silva, S.; Luís, R.; Baldaia, C.; Silva, S.L.. "Nodular regenerative hyperplasia in CVID patients: could low-dose oral glucocorticoids be part of the solution?". European Annals of Allergy and Clinical Immunology 55 06 (2023): 313. http://dx.doi.org/10.23822/eurannaci.1764-1489.251.
    10.23822/eurannaci.1764-1489.251
  9. Varandas, Cláudia; Presa, Ana; Ferreira, Rúben; Silva, Sara; Silva, Susana; Cláudia Varandas; Ana Presa; et al. "Infeção por SARS-CoV-2 nos doentes com agamaglobulinemia ligada ao X". Revista Portuguesa de Imunoalergologia 31 (2023): http://dx.doi.org/10.32932/rpia.2023.08.117.
    10.32932/rpia.2023.08.117
  10. Joana, Queirós Gomes; Sara, Silva; Tiago, Marques; Susana, Lopes da Silva. "Goods’s Syndrome: Immunodeficiency Beyond Thymectomy". (2023):
    10.48729/pjctvs.313
  11. Sofia Couto; Sara P Silva; Célia osta; Susana L Silva. "Hiperplasia nodular linfóide no intestino em adultos com Imunodeficiência comum variável". Revista Portuguesa de Imunoalergologia 31 2 (2023): http://dx.doi.org/10.32932/rpia.2023.06.115.
    10.32932/rpia.2023.06.115
  12. Ana Presa; Cláudia Varandas; Leonor Caldeira; Ruben Ferreira; Tiago Marques; Sara Silva; José Marques; Susana Silva. "Doença granulomatosa crónica no adulto: Evolução clínica e opções terapêuticas". Revista Portuguesa de Imunoalergologia (2023): https://doi.org/10.32932/rpia.2023.06.113.
    10.32932/rpia.2023.06.113
  13. Varandas, C.; Vieira, J.; Correia, C.J.; Paulino, M.; Spínola Santos, A.; Lopes, A.; Lopes Da Silva, S.; Pedro, E.; Caiado, J.. "Hypersensitivity reactions to iron products: 10-year experience in a Portuguese tertiary Centre". European Annals of Allergy and Clinical Immunology online fir (2023): http://dx.doi.org/10.23822/eurannaci.1764-1489.290.
    10.23822/eurannaci.1764-1489.290
  14. Bernardino,Ana; Costa,Célia; Silva,Maria Inês T.; Mendes,Ana; Santos,Amélia Spínola; Silva,Susana L.; Neto,Marta; et al. "Autoadministração de omalizumab na urticária crónica espontânea - Estudo observacional num centro UCARE". Revista Portuguesa de Imunoalergologia (2023): http://scielo.pt/scielo.php?script=sci_arttext&pid=S0871-97212023000200123.
    10.32932/rpia.2023.04.109
  15. Gomes, André M. C.; Farias, Guilherme B.; Trombetta, Amelia C.; Godinho-Santos, Ana; Parreira, Inês; Gonçalves, Hélder Diogo; Simões, Mariana Lessa; et al. "Phenotype of BTK-lacking myeloid cells during prolonged COVID-19 and upon convalescent plasma". European Journal of Haematology 110 2 (2022): 209-212. http://dx.doi.org/10.1111/ejh.13881.
    10.1111/ejh.13881
  16. Susana Silva. "Imunoalergologistas – O que nos distingue, o que queremos acrescentar?". Revista Portuguesa de Imunoalergologia (2022): https://doi.org/10.32932/rpia.2022.09.085.
    10.32932/rpia.2022.09.085
  17. Cláudia Varandas; Maria Conceição Pereira-Santos; Marta Neto; Ana E. Sousa; Anabela Lopes; Susana L. Silva. "Serum IL-22 binding protein as a marker for atopic dermatitis activity and response to dupilumab treatment". Clinical & Experimental Allergy 52 6 (2022): 820-823. https://doi.org/10.1111/cea.14147.
    10.1111/cea.14147
  18. Motta-Raymundo, Adriana; Rosmaninho, Pedro; Santos, Diana F.; Ferreira, Ruben D.; Silva, Sara P.; Ferreira, Cristina; Sousa, Ana E.; Silva, Susana L.. "Contribution of Helicobacter pylori to the Inflammatory Complications of Common Variable Immunodeficiency". Frontiers in Immunology 13 (2022): http://dx.doi.org/10.3389/fimmu.2022.834137.
    10.3389/fimmu.2022.834137
  19. Thalhammer, Julian; Kindle, Gerhard; Nieters, Alexandra; Rusch, Stephan; Seppänen, Mikko R.J.; Fischer, Alain; Grimbacher, Bodo; et al. "Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations". Journal of Allergy and Clinical Immunology 148 5 (2021): 1332-1341.e5. http://dx.doi.org/10.1016/j.jaci.2021.04.015.
    10.1016/j.jaci.2021.04.015
  20. Globig, Anna-Maria; Heeg, Maximilian; Larsen, Carsten Schade; Ferreira, Ruben Duarte; Kindle, Gerhard; Goldacker, Sigune; Strohmeier, Valentina; et al. "International multicenter experience of transjugular intrahepatic portosystemic shunt implantation in patients with common variable immunodeficiency". The Journal of Allergy and Clinical Immunology: In Practice (2021): http://dx.doi.org/10.1016/j.jaip.2021.02.056.
    10.1016/j.jaip.2021.02.056
  21. Gullo, Irene; Costa, Catarina; Silva, Susana L.; Ferreira, Cristina; Motta, Adriana; Silva, Sara P.; Ferreira, Rúben Duarte; et al. "The Dysfunctional Immune System in Common Variable Immunodeficiency Increases the Susceptibility to Gastric Cancer". Cells 9 6 (2020): 1498. http://dx.doi.org/10.3390/cells9061498.
    Open access • Published • 10.3390/cells9061498
  22. Silva, Susana L.; Fonseca, Mariana; Pereira, Marcelo L. M.; Silva, Sara P.; Barbosa, Rita R.; Serra-Caetano, Ana; Blanco, Elena; et al. "Monozygotic Twins Concordant for Common Variable Immunodeficiency: Strikingly Similar Clinical and Immune Profile Associated With a Polygenic Burden". Frontiers in Immunology 10 (2019): http://dx.doi.org/10.3389/fimmu.2019.02503.
    10.3389/fimmu.2019.02503
  23. Blanco, Elena; Pérez-Andrés, Martín; Arriba-Méndez, Sonia; Serrano, Cristina; Criado, Ignacio; Del Pino-Molina, Lucía; Silva, Susana; et al. "Defects in memory B-cell and plasma cell subsets expressing different immunoglobulin-subclasses in patients with CVID and immunoglobulin subclass deficiencies". Journal of Allergy and Clinical Immunology 144 3 (2019): 809-824. http://dx.doi.org/10.1016/j.jaci.2019.02.017.
    10.1016/j.jaci.2019.02.017
  24. McDermott, David H.; Pastrana, Diana V.; Calvo, Katherine R.; Pittaluga, Stefania; Velez, Daniel; Cho, Elena; Liu, Qian; et al. "Plerixafor for the Treatment of WHIM Syndrome". New England Journal of Medicine 380 2 (2019): 163-170. http://dx.doi.org/10.1056/nejmoa1808575.
    10.1056/nejmoa1808575
  25. Fonseca, Valter R.; Agua-Doce, Ana; Maceiras, Ana Raquel; Pierson, Wim; Ribeiro, Filipa; Romão, Vasco C.; Pires, Ana Rita; et al. "Human blood T fr cells are indicators of ongoing humoral activity not fully licensed with suppressive function". Science Immunology 2 14 (2017): eaan1487. http://dx.doi.org/10.1126/sciimmunol.aan1487.
    10.1126/sciimmunol.aan1487
  26. Silva, Susana L.; Albuquerque, Adriana; Amaral, Andreia J.; Li, Quan-Zhen; Mota, Catarina; Cheynier, Rémi; Victorino, Rui M. M.; Pereira-Santos, M. Conceição; Sousa, Ana E.. "Autoimmunity and allergy control in adults submitted to complete thymectomy early in infancy". PLOS ONE 12 7 (2017): e0180385. http://dx.doi.org/10.1371/journal.pone.0180385.
    10.1371/journal.pone.0180385
  27. Albuquerque, Adriana S.; Fernandes, Susana M.; Tendeiro, Rita; Cheynier, Rémi; Lucas, Margarida; Silva, Susana L.; Victorino, Rui M. M.; Sousa, Ana E.. "Major CD4 T-Cell Depletion and Immune Senescence in a Patient with Chronic Granulomatous Disease". Frontiers in Immunology 8 (2017): http://dx.doi.org/10.3389/fimmu.2017.00543.
    10.3389/fimmu.2017.00543
  28. Silva, Susana L.; Albuquerque, Adriana S.; Matoso, Paula; Charmeteau-de-Muylder, Bénédicte; Cheynier, Rémi; Ligeiro, Dário; Abecasis, Miguel; et al. "IL-7-Induced Proliferation of Human Naive CD4 T-Cells Relies on Continued Thymic Activity". Frontiers in Immunology 8 (2017): http://dx.doi.org/10.3389/fimmu.2017.00020.
    10.3389/fimmu.2017.00020
  29. Silva, Susana L.; Sousa, Ana E.. "Establishment and Maintenance of the Human Naïve CD4+ T-Cell Compartment". Frontiers in Pediatrics 4 (2016): http://dx.doi.org/10.3389/fped.2016.00119.
    10.3389/fped.2016.00119
  30. Amorim, A.; Gamboa, F.; Sucena, M.; Cunha, K.; Anciães, M.; Lopes, S.; Pereira, S.; et al. "Recommendations for aetiological diagnosis of bronchiectasis". Revista Portuguesa de Pneumologia (English Edition) 22 4 (2016): 222-235. http://dx.doi.org/10.1016/j.rppnen.2016.03.004.
    10.1016/j.rppnen.2016.03.004
  31. Silva, Susana L.; Albuquerque, Adriana S.; Serra-Caetano, Ana; Foxall, Russell B.; Pires, Ana R.; Matoso, Paula; Fernandes, Susana M.; et al. "Human naive regulatory T-cells feature high steady-state turnover and are maintained by IL-7". Oncotarget 7 11 (2016): http://dx.doi.org/10.18632/oncotarget.7512.
    10.18632/oncotarget.7512
  32. Silva, Susana L. "Severe Bronchiectasis in a Patient With Common Variable Immunodeficiency". European Annals of Allergy and Clinical Immunology 47 3 (2015): 95-98.
  33. Barbosa, Rita R.; Silva, Susana L.; Silva, Sara P.; Melo, Alcinda C.; Pereira-Santos, M. Conceição; Barata, João T.; Hammarström, Lennart; Cascalho, Marília; Sousa, Ana E.. "Reduced BAFF-R and Increased TACI Expression in Common Variable Immunodeficiency". Journal of Clinical Immunology 34 5 (2014): 573-583. http://dx.doi.org/10.1007/s10875-014-0047-y.
    10.1007/s10875-014-0047-y
  34. Barbosa, R. R.; Silva, S. P.; Silva, S. L.; Tendeiro, R.; Melo, A. C.; Pedro, E.; Barbosa, M. P.; et al. "Monocyte activation is a feature of common variable immunodeficiency irrespective of plasma lipopolysaccharide levels". Clinical & Experimental Immunology 169 3 (2012): 263-272. http://dx.doi.org/10.1111/j.1365-2249.2012.04620.x.
    10.1111/j.1365-2249.2012.04620.x
  35. Albuquerque, Adriana S.; Marques, José G.; Silva, Susana L.; Ligeiro, Dario; Devlin, Blythe H.; Dutrieux, Jacques; Cheynier, Rémi; et al. "Human FOXN1-Deficiency Is Associated with aß Double-Negative and FoxP3+ T-Cell Expansions That Are Distinctly Modulated upon Thymic Transplantation". PLoS ONE 7 5 (2012): e37042. http://dx.doi.org/10.1371/journal.pone.0037042.
    10.1371/journal.pone.0037042
  36. Barbosa, Rita R.; Silva, Sara P.; Silva, Susana L.; Melo, Alcinda Campos; Pedro, Elisa; Barbosa, Manuel P.; Pereira-Santos, M. Conceição; Victorino, Rui M. M.; Sousa, Ana E.. "Primary B-Cell Deficiencies Reveal a Link between Human IL-17-Producing CD4 T-Cell Homeostasis and B-Cell Differentiation". PLoS ONE 6 8 (2011): e22848. http://dx.doi.org/10.1371/journal.pone.0022848.
    10.1371/journal.pone.0022848
  37. Reis Boto, Maria Leonor; Sandes, Ana Rita; Brites, Anabela; Silva, Susana; Stone, Rosário; Almeida, Margarida. "Severe immune haemolytic anaemia due to ceftriaxone in a patient with congenital nephrotic syndrome". Acta Paediatrica 100 10 (2011): e191-e193. http://dx.doi.org/10.1111/j.1651-2227.2011.02268.x.
    10.1111/j.1651-2227.2011.02268.x
  38. Markert, M. Louise; Marques, José G.; Neven, Bénédicte; Devlin, Blythe H.; McCarthy, Elizabeth A.; Chinn, Ivan K.; Albuquerque, Adriana S.; et al. "First use of thymus transplantation therapy for FOXN1 deficiency (nude/SCID): a report of 2 cases". Blood 117 2 (2011): 688-696. http://dx.doi.org/10.1182/blood-2010-06-292490.
    10.1182/blood-2010-06-292490
  39. Rodrigues-Alves, Rodrigo; Lopez, Anabela; Pereira-Santos, Maria Conceição; Lopes-Silva, Susana; Spínola-Santos, Amélia; Costa, Célia; Branco-Ferreira, Manuel; Lidholm, Jonas; Pereira-Barbosa, Manuel. "Clinical, Anamnestic and Serological Features of Peach Allergy in Portugal". International Archives of Allergy and Immunology 149 1 (2008): 65-73. http://dx.doi.org/10.1159/000176308.
    10.1159/000176308
  40. Lopes-da-Silva, Susana; Rizzo, Luiz Vicente. "Autoimmunity in Common Variable Immunodeficiency". Journal of Clinical Immunology 28 S1 (2008): 46-55. http://dx.doi.org/10.1007/s10875-008-9172-9.
    10.1007/s10875-008-9172-9
  41. Detková, Drahomíra; de Gracia, Javier; Lopes-da-Silva, Susana; Vendrell, Montserrat; Alvarez, Antonio; Guarner, Luisa; Vidaller, Antonio; et al. "Common Variable Immunodeficiency: association between memory B cells and lung diseases". Chest 131 6 (2007): 1883-1889. http://dx.doi.org/10.1378/chest.06-2994.
    10.1378/chest.06-2994
Preprint
  1. Raposo, AASF; Rosmaninho, Pedro; Susana Lopes-da-Silva; Paço, Susana; Brazão, Maria E.; Godinho-Santos, Ana; Tokunaga-Mizoro, Yumie; et al. Corresponding author: Raposo, AASF. "Decoding mutational hotspots in human disease through the gene modules governing thymic regulatory T cells". 2023. http://dx.doi.org/10.1101/2023.12.27.573411.
    10.1101/2023.12.27.573411
Thesis / Dissertation
  1. Cochicho, Joana Gomes. "Allergy in young adults submitted to thymectomy early in infancy". Master, 2016. http://hdl.handle.net/10451/27443.
Activities

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2021/03/01 - Current Deciphering complex inborn errors of immunity through the integration of clinical data, high-dimensional immune profile and whole-genome sequencing
Supervisor
Universidade de Lisboa Faculdade de Medicina, Portugal
2022 - 2022 "Contribution of Helicobacter pylori infection to the clinical and immunological profile of Common Variable Immunodeficiency"
Supervisor
 Microbiologia Clínica e Doenças Infecciosas Emergentes (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
2021 - 2021 Homeostasia do ferro em doentes com asma
Supervisor
 Medicina (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
2019/09/01 - 2020/07/30 Complex CVID and Familial Autoimmunity: a Case Report
Supervisor
Universidade de Lisboa Faculdade de Medicina, Portugal
2019/09/01 - 2020/07/30 Classification of patients with Common Variable Immunodeficiency - different strategies
Supervisor
Universidade de Lisboa Faculdade de Medicina, Portugal
2018 - 2018 Adenocarcinoma Gástrico em Doentes com Imunodeficiência Comum Variável
Supervisor
 Medicina (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
2016 - 2016 From immune phenotype to clinical manifestations in CVID
Supervisor
 Medicina (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
2015 - 2016 From immune phenotype to clinical manifestations in CVID
Supervisor
 Mestrado Integrado em Medicina (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
2015 - 2016 Allergy in young adults submitted to thymectomy early in infancy
Supervisor
 Mestrado Integrado em Medicina (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
2015 - 2015 Urticária Crónica, associação a Tiroidite Autoimune, Revisão a propósito de um caso clínico
Supervisor
 Medicina (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
2013 - 2014 Urticária Crónica, associação a Tiroidite Autoimune
Supervisor
 Mestrado Integrado em Medicina (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal

Association member

Society Organization name Role
2013 - Current Sociedade Portuguesa de Imunologia Member of the Direction Board of Sociedade Portuguesa de Imunologia (SPI) 2015 - 2018
2006 - Current Grupo Português de Imunodeficiências Primárias / Sociedade Portuguesa de Imunologia Member of the Board 2006 - 2008
2002 - Current European Society for Immunodeficiency (ESID)
2001 - Current Sociedade Portuguesa de Alergologia e Imunologia Clínica Coordination Grupo de Interesse de Imunodeficiências Primárias (2010-2017)
2000 - Current European Academy of Allergy and Clinical Immunology Member

Committee member

Activity description
Role 		Institution / Organization
2021/01/01 - Current Membro do Grupo de Trabalho nomeado pela DGS para apoio à realização sobre normas para vacinação anti SARS COV 2 - avaliação de reações de provavel alergia
Member
2011 - Current Editoral Board of Revista Portuguesa de Alergologia e Imunologia Clínica
Member
2009 - 2022 Member of the Board of Comissão Executiva da Comissão Técnica de Vacinas, Direcção Geral de Saúde
Member

Consulting

Activity description Institution / Organization
2013 - Current Medical Advisor Associação Portuguesa de Dontes com Imunodeficiências Primárias

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2018 - Current Master-course Clinical Microbiology and Emerging Infectious Diseases (Mestrado) Universidade de Lisboa Faculdade de Medicina, Portugal
2016 - Current Clinical Immunology / Medicina 2 - 5th year of the Medical Course - Faculdade de Medicina da Universidade de Lisboa Estudos Básicos de Medicina (Licenciatura) Universidade de Lisboa Faculdade de Medicina, Portugal
2015 - Current Clinical Immunology - optative discipline of the Medical Course - Faculdade de Medicina da Universidade de Lisbo (Mestrado integrado) Universidade de Lisboa Faculdade de Medicina, Portugal