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Fernando Remião. Concluiu o Título de Agregado em Toxicologia em 2015 pela Universidade do Porto Faculdade de Farmácia, Doutoramento em Toxicologia em 2002 pela Universidade do Porto Faculdade de Farmácia, Provas de Aptidão Pedagógica em 1998 pela Universidade do Porto Faculdade de Farmácia e Licenciatura em Pharmaceutical Sciences em 1993 pelo(a) Universidade do Porto Faculdade de Farmácia. É Professor Associado no Departamento de Ciências Biológicas na Universidade do Porto Faculdade de Farmácia. Publicou 149 artigos em revistas especializadas. Possui 1 livro(s). Recebeu 3 prémio(s) e/ou homenagens. No seu currículo Ciência Vitae os termos mais frequentes na contextualização da produção científica, tecnológica e artístico-cultural são: Medicina básica; Basic medicine; Ciências médicas e da saúde::Medicina básica; Medical and Health sciences::Basic medicine; Ciências da educação, Ciências da educação; Educational sciences, Educational sciences; Ciências sociais::Ciências da educação; Social sciences::Educational sciences; ensino superior; inovação; património cultural; Mitoxantrone; Cardiotoxicity; Mitochondria; Modos de utilização de um Recurso Educacional; Experiência digital; experiência fenomenológica; encontros educacionais; Paraquat; Sodium salicylate; Charge-transfer complexes; Trabalhos-projeto; Interação entre pares; Avaliação; Metabolism; Bioactivation; LC/MS; S9 fraction; MULTIPLE-SCLEROSIS; PROTEIN-SYNTHESIS; LIVER; HEPATOTOXICITY; CELLS; TOXICITY; PHARMACOKINETICS; CARDIOTOXICITY; CHEMOTHERAPY; INHIBITION; Energetic failure; Oxidative stress; Energetic imbalance; Toxicologia; Catecolaminas; Óxido de alumínio; Cromatografia líquida; Brassica oleracea var. acephala; Pieris brassicae; Phenolic compounds; V79 cells; Glutathione status; .
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Identification

Personal identification

Full name
Fernando Remião

Citation names

  • Remião, Fernando

Author identifiers

Ciência ID
D11B-8F58-AF98
ORCID iD
0000-0003-1382-5119

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Toxicology
  • Social Sciences - Educational Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
English Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
French Intermediate (B1) Intermediate (B1) Beginner (A1) Intermediate (B1)
Education
Degree Classification
2015/07/21
Concluded
 Ciências Farmacêuticas - especialização Toxicologia (Título de Agregado)
Major in Toxicologia
Universidade do Porto Faculdade de Farmácia, Portugal
"n/a" (THESIS/DISSERTATION)
 Approved by unanimity
2002/12/16
Concluded
 Ciências Farmacêuticas - especialização Toxicologia (Doutoramento)
Major in Toxicologia
Universidade do Porto Faculdade de Farmácia, Portugal
"Cardiotoxicidade do Isoproterenol e dos Produtos da Sua Oxidação - Estudos Mecanísticos em Suspensões de Cardiomiócitos Isolados de Ratos Adultos" (THESIS/DISSERTATION)
1998
Concluded
 Aptidão Pedagógica e Capacidade Científica (Mestrado)
Major in Toxicologia
Universidade do Porto Faculdade de Farmácia, Portugal
"The heart as target organ of toxicity - use of isolated cardiomyocytes from adult rat for cardiotoxicity studies" (THESIS/DISSERTATION)
 Very Good
1993
Concluded
 Pharmaceutical Sciences (Licenciatura)
Universidade do Porto Faculdade de Farmácia, Portugal
"Not applicable" (THESIS/DISSERTATION)
 15/20
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2008/02/18 - Current Associate Professor (University Teacher) Universidade do Porto Faculdade de Farmácia, Portugal
2002/12/16 - 2008/02/17 Assistant Professor (University Teacher) Universidade do Porto Faculdade de Farmácia, Portugal
1998/03/20 - 2002/12/15 Assistant (University Teacher) Universidade do Porto Faculdade de Farmácia, Portugal
1995/11/02 - 1998/03/19 Trainee Assistant (University Teacher) Universidade do Porto Faculdade de Farmácia, Portugal

Positions / Appointments

Category
Host institution 		Employer
2019/05 - Current Director de Curso do Mestrado Integrado em Ciências Farmacêuticas Universidade do Porto Faculdade de Farmácia, Portugal
2017/04/17 - Current Editor Associado da Revista "Toxicology and Applied Pharmacology" Elsevier Inc, United States
Universidade do Porto Faculdade de Farmácia, Portugal
(...)
2016/04 - Current Coordenador ECTS da Faculdade de Farmácia Universidade do Porto Faculdade de Farmácia, Portugal
2014/05 - Current Membro da Comissão Cientifica - Mestrado em Toxicologia Analítica Clínica e Forense Universidade do Porto Faculdade de Farmácia, Portugal
2014/01 - Current Investigador Sénior na Unidade de Investigação em Ciências Biomoleculares Aplicadas (UCIBIO, REQUIMTE) Universidade do Porto Faculdade de Farmácia, Portugal
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2002/12/16 - Current Membro do Conselho científico da Faculdade de Farmácia Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2019/02 - 2023/02 Membro Cooptado do Conselho Cientifico da Faculdade de Psicologia e Ciências da Educação Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Psicologia e de Ciências da Educação, Portugal
2019/02 - 2022/02 Membro da Direção (Tesoureiro) da Sociedade Portuguesa de Farmacologia Universidade do Porto Faculdade de Farmácia, Portugal
Sociedade Portuguesa de Farmacologia, Portugal
2019/05 - 2020/02 Membro do Conselho Pedagógico da Faculdade de Farmácia Universidade do Porto Faculdade de Farmácia, Portugal
2014/06/27 - 2018/06/27 Pro-Rector Universidade do Porto, Portugal
Universidade do Porto, Portugal
2014/06 - 2018/06 Responsável, enquanto Pró-Reitor, pela Unidade de "Inovação Pedagógica" da Universidade do Porto Universidade do Porto, Portugal
Universidade do Porto, Portugal
2010/11/08 - 2015/05/01 President of the Pedagogic Council Universidade do Porto Faculdade de Farmácia, Portugal
2007/02 - 2015/05 Coordenador do Gabinete de Relações Exteriores (Programas de mobilidade) Universidade do Porto Faculdade de Farmácia, Portugal
2013/09 - 2014/11 Membro da Comissão de Acompanhamento de Curso - Mestrado em Toxicologia Analítica Clínica e Forense Universidade do Porto Faculdade de Farmácia, Portugal
2002/01 - 2013/12 Investigador Sénior no Laboratório Associado REQUIMTE (Rede de Química e Tecnologia) Universidade do Porto Faculdade de Farmácia, Portugal
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2007/06/01 - 2011/11/01 Membro da Comissão Cientifica - Mestrado em Toxicologia Analítica Clínica e Forense Universidade do Porto Faculdade de Farmácia, Portugal
2002 - 2007/02 Membro do Gabinete de Relações Exteriores (programas de mobilidade) Universidade do Porto Faculdade de Farmácia, Portugal
2002/03/01 - 2004/04/01 Membro do Conselho Directivo Universidade do Porto Faculdade de Farmácia, Portugal
1996/01 - 2001/12 Investigador no Instituto de Ciências e Tecnologias Agrárias e Agroalimentares/Centro de Química da Universidade do Porto Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

Others

Category
Host institution 		Employer
1993/09/01 - 1995/09/01 Researcher in Faculty of Pharmacy - University of Porto - BJI 1643 Associação Nacional de Farmácias, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
1993/09/01 - 1994/09/01 Scholar - Grant for younger researchers Fundação para a Ciência e a Tecnologia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
Projects

Contract

Designation Funders
2015/01 - Current UnIdade Ciências Biomoleculares Aplicadas
4378
Researcher
Fundação para a Ciência e a Tecnologia
Ongoing
2021/12/01 - 2024/11/30 INES: Innovative teaching and learning paths for the prevention of new drugs abuse
2021-1-IT02-KA220-SCH-000032570
Principal investigator
Universidade do Porto Faculdade de Farmácia, Portugal
 Erasmus Plus
Ongoing
2021/02/01 - 2024/01/31 Pensos antimicrobianos e halocrómicos à base de fibras para o tratamento de feridas baseados em novas moléculas derivadas de pirimidina
PTDC/CTM-TEX/1213/2020
Researcher
Universidade do Minho, Portugal

Centro de Ciência e Tecnologia Têxtil, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2019/09/01 - 2023/08/31 OEMONOM: Open access Educational Materials on Naturally Occurring Molecules - sources, biological activity and use
2020-1-CZ01-KA203-078218
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
 European Commission
Ongoing
2021/03 - 2023/08 SUCTIA - SYSTEMIC UNIVERSITY CHANGE TOWARDS INTERNATIONALISATION for Academia
2019-1-PL01-KA203-065656
Researcher
European Comission
Ongoing
2018 - 2021/05 Antimicrobials from the sea: models for innovative agents to revert multidrug resistance” antimicrobial resistance in health and aquatic pollution
POCI-01-0145-FEDER-028736
Researcher
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2017/10 - 2020/10 PRINTeL - Change in Classroom: Promoting Innovative Teaching & Learning to Enhance Student Learning Experience in Eastern Partnership Countries
585760-EPP-1-2017-1-AM-EPPKA2-CBHE-JP
Principal investigator
Universidade do Porto, Portugal
 European Commission
Ongoing
2017/10 - 2020/10 PRINTeL - Change in Classroom: Promoting Innovative Teaching & Learning to Enhance Student Learning Experience in Eastern Partnership Countries
585760-EPP-1-2017-1-AM-EPPKA2-CBHE-JP
 European Commission
2016/10 - 2019/10 e-VAL Exploração e valorização de conhecimentos para uma melhor inserção e visibilidade profissionais
573674-EPP-1-2016-1-ES-EPPKA2-CBHE-SP
Principal investigator
Universidade do Porto, Portugal
 European Commission
Concluded
2015/12 - 2019/02 EFFECT - European Forum for Enhanced Collaboration in Teaching - a feasibility study
562147-EPP-1-2015-1-BE-EPPKA3-PI-FORWARD
Principal investigator
Universidade do Porto, Portugal
 European Commission
Concluded
2015/09 - 2018/02 TOX-OER - Learning Toxicology through Open Educational Resources
2015-1-ES01-KA203-015957
Principal investigator
Universidade do Porto Faculdade de Farmácia, Portugal
 European Commission
Concluded
2013/05/01 - 2014/10/31 Porque é a mitoxantrona um veneno para o coração? Em destaque os mecanismos mitocondriais, sobre o citoesqueleto e de bioactivação metabólica.
EXPL/DTP-FTO/0290/2012
Researcher
Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade do Porto Faculdade de Desporto, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/02/05 - 2013/08/03 Desenvolvimento e aplicação de indutores da glicoproteína-P na profilaxia e terapêutica da toxicidade de xenobióticos
PTDC/SAU-OSM/101437/2008
Principal investigator
Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade de Aveiro, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2007/10/01 - 2009/09/30 OXIDATIVE STRESS IN HEART DISEASE: ROLE OF CATECHOLAMINES
info:eu-repo/grantAgreement/FCT/POCI/55849/PT
Principal investigator
Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2005/06/01 - 2008/06/30 Estudos farmacogenéticos para avaliação da influência do metabolismo na expressão da toxicidade de derivados anfetamínicos usados correntemente como drogas de abuso
POCI/SAU-FCF/57187/2004
Researcher
REQUIMTE LAQV Porto, Portugal

Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2005/10/01 - 2007/12/31 Stress oxidativo na Doença Cardíaca: acção das catecolaminas
POCI/SAU-OBS/55849/2004
Principal investigator
REQUIMTE LAQV Porto, Portugal

Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal

Universidade de Aveiro, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2019 - Current Evaluation of Curriculum Development: a transdisciplinary approach
FFUP/FPCEUP/FEUP
Researcher
Universidade do Porto Centro de Investigação e Intervenção Educativas, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
Outputs

Publications

Book
  1. Carvalho, F.; Carmo, H.; Guedes de Pinho, P.; Remião, F.; de Lourdes Bastos, M.; Carvalho, M.. Mephedrone. 2014.
    10.1016/B978-0-12-386454-3.01189-1
Book chapter
  1. Remião, Fernando; Ma¨kela¨, Merja. "Learning recognition / Reconocimiento del aprendizage". In Challenges in Open Educational Resources: The Case of TOX-OER MOOC / Retos en los Recursos Educativos Abiertos: Desarrollo del MOOC TOX-OER, 123-134. Salamanca, Spain: Editorial Amarante, 2018.
    Published
  2. Renata Silva; Remião, Fernando; Ricardo Jorge Dinis-Oliveira; Félix Dias Carvalho; Maria de Lourdes Bastos. "Toxicocinética". In Toxicologia Fundamental, edited by Ricardo Jorge Dinis-Oliveira; Félix Dias Carvalho; Maria de Lourdes Bastos, 9-33. Lisboa, Portugal: Lidel, 2018.
    Published
  3. Remião, Fernando; Maria de Lourdes Bastos. "Disposição dos xenobióticos nos sistemas biológicos: absorção, distribuição, metabolismo, excreção e transporte (ADMET)". In Toxicologia Forense, edited by Ricardo Jorge Dinis-Oliveira; Félix Dias Carvalho; Maria de Lourdes Bastos, 9-58. Lisboa, Portugal: Pactor, 2015.
    Published
  4. Marisa, Vera; Carvalho, Flix; Lourdes, Maria; Albuquerque, Rui; Carvalho, Márcia; Remião, Fernando (D11B-8F58-AF98). "Adrenaline and Noradrenaline: Partners and Actors in the Same Play". In Neuroscience - Dealing With Frontiers. InTech, 2012.
    10.5772/36070
Conference abstract
  1. Maria Amélia Veiga; Remião, Fernando; João Pêgo; Fátima Matos; Olga Lage. "Aulas invertidas: relato de um estudo transdisciplinar". Paper presented in CNaPPES 2019 -Congresso Nacional de Práticas Pedagógicas no Ensino Superior, Santarém, 2019.
    Published
  2. Remião, Fernando; Helena Carmo; António Miguel Gomes; Renata Silva; Vera Marisa Costa; Félix Dias Carvalho; Maria de Lourdes Bastos. "Video lecture capture (VLC) - impacto na aprendizagem dos estudantes". Paper presented in CNaPPES 2019 -Congresso Nacional de Práticas Pedagógicas no Ensino Superior, Santarém, 2019.
    Published
Conference paper
  1. Barbara Silva; Joana Saraiva Rodrigues; Joana Paiva Miranda; Ana Sofia Almeida; Carla Fernandes; Paula Guedes de Pinho; Fernando Remião. "Metabolism of Cathinones in Functional Hepatocyte-like Cells Derived from Human Neonatal Mesenchymal Stem Cells: An Enantioselectivity Approach". 2022.
    10.3390/ECMC2022-13302
  2. Remião, Fernando; Carolina Rocha-Pereira; Renata Silva; Vera Marisa Costa; Jorge Soares; Helena Carmo; Félix Dias Carvalho; Maria de Lourdes Bastos. "TOX-OER MOOC : uma ferramenta para o ensino e a aprendizagem". Paper presented in CNaPPES 2018 – Congresso Nacional de Práticas Pedagógicas no Ensino Superior, Braga, 2018.
    Published
  3. Fernandes, F.; Teixeira, J.P.; Taveira, M.; Sousa, C.; Costa, Solange; Coelho, P.; Valentão, P.; et al. "Pieris brassicae excrements: cytological effects". 2009.
Edited book
  1. Remião, Fernando. Livro de Atas do CNaPPES 2018 – Congresso Nacional de Práticas Pedagógicas no Ensino Superior. Braga, Portugal. 2018.
    Published • Editor
  2. Remião, Fernando. Livro de Atas do CNaPPES 2017 – Congresso Nacional de Práticas Pedagógicas no Ensino Superior. Setúbal. 2017.
    Published • Editor
  3. Remião, Fernando. Livro de Atas do CNaPPES 2016 – Congresso Nacional de Práticas Pedagógicas no Ensino Superior. Lisboa. 2016.
    Published • Editor
  4. Remião, Fernando. Livro de Atas do CNaPPES 2015 – Congresso Nacional de Práticas Pedagógicas no Ensino Superior. Leiria, Portugal. 2015.
    Published • Editor
Journal article
  1. Inês Costa; Daniel José Barbosa; Sofia Benfeito; Vera Silva; Daniel Chavarria; Fernanda Borges; Fernando Remião; Renata Silva. "Molecular mechanisms of ferroptosis and their involvement in brain diseases". Pharmacology & Therapeutics 244 (2023): 108373-108373. http://dx.doi.org/10.1016/j.pharmthera.2023.108373.
    10.1016/j.pharmthera.2023.108373
  2. Joana Torres; José Miguel Pereira; Rita Marques-Oliveira; Inês Costa; Eva Gil-Martins; Renata Silva; Fernando Remião; et al. "An In Vitro Evaluation of the Potential Neuroprotective Effects of Intranasal Lipid Nanoparticles Containing Astaxanthin Obtained from Different Sources: Comparative Studies". Pharmaceutics (2023): https://doi.org/10.3390/pharmaceutics15041035.
    10.3390/pharmaceutics15041035
  3. Ana Isabel Ribeiro; Bárbara Vieira; Daniela Dantas; Bárbara Silva; Eugénia Pinto; Fátima Cerqueira; Renata Silva; et al. "Synergistic Antimicrobial Activity of Silver Nanoparticles with an Emergent Class of Azoimidazoles". Pharmaceutics (2023): https://doi.org/10.3390/pharmaceutics15030926.
    10.3390/pharmaceutics15030926
  4. Ana Sofia Almeida; Bárbara Silva; João Pedro Silva; José Augusto Pereira; Fernando Remião; Carla Fernandes. "Semi-Preparative Separation, Absolute Configuration, Stereochemical Stability and Effects on Human Neuronal Cells of MDPV Enantiomers". Molecules (2023): https://doi.org/10.3390/molecules28052121.
    10.3390/molecules28052121
  5. Sofia Benfeito; Carlos Fernandes; Daniel Chavarria; Sandra Barreiro; Fernando Cagide; Lisa Sequeira; José Teixeira; et al. "Modulating Cytotoxicity with Lego-like Chemistry: Upgrading Mitochondriotropic Antioxidants with Prototypical Cationic Carrier Bricks". Journal of Medicinal Chemistry (2023): https://doi.org/10.1021/acs.jmedchem.2c01630.
    10.1021/acs.jmedchem.2c01630
  6. Ana Sofia Almeida; Bárbara Silva; Fernando Remião; Carla Fernandes. "Assessment of the Permeability of 3,4-Methylenedioxypyrovalerone (MDPV) across the Caco-2 Monolayer for Estimation of Intestinal Absorption and Enantioselectivity". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24032680.
    10.3390/ijms24032680
  7. Ana Reis-Mendes; Félix Carvalho; Fernando Remião; Emília Sousa; Maria de Lourdes Bastos; Vera Marisa Costa. "Autophagy (but not metabolism) is a key event in mitoxantrone-induced cytotoxicity in differentiated AC16 cardiac cells". Archives of Toxicology (2023): https://doi.org/10.1007/s00204-022-03363-6.
    10.1007/s00204-022-03363-6
  8. Daniela Dantas; Ana Ribeiro; Filipe Carvalho; Eva Gil-Martins; Renata Silva; Fernando Remião; Zille Andrea; et al. "Red-shifted and pH-responsive imidazole-based azo dyes with potent antimicrobial activity". Chemical Communications 59 19 (2023): 2791-2794. http://dx.doi.org/10.1039/d3cc00372h.
    10.1039/d3cc00372h
  9. Vera Marisa Costa; Luciana Grazziotin Rossato Grando; Elisa Milandri; Jessica Nardi; Patrícia Teixeira; Premysl Mladenka; Fernando Remião. "Natural Sympathomimetic Drugs: From Pharmacology to Toxicology". Biomolecules (2022): https://doi.org/10.3390/biom12121793.
    10.3390/biom12121793
  10. Jirí Janoušek; Veronika Pilarová; Katerina Macáková; Anderson Nomura; Jéssica Veiga-Matos; Diana Dias da Silva; Fernando Remião; et al. "Vitamin D: sources, physiological role, biokinetics, deficiency, therapeutic use, toxicity, and overview of analytical methods for detection of vitamin D and its metabolites". Critical Reviews in Clinical Laboratory Sciences (2022): https://doi.org/10.1080/10408363.2022.2070595.
    10.1080/10408363.2022.2070595
  11. Fernando Remião; Helena Carmo; Miguel Gomes; Renata Silva; Vera Marisa Costa; Félix Carvalho; Maria de Lourdes Bastos. "The impact of video lecture capture on student attainment and achievement of intended learning outcomes". Pharmacy Education (2022): https://doi.org/10.46542/pe.2022.221.843855.
    10.46542/pe.2022.221.843855
  12. Sandra Barreiro; Bárbara Silva; Solida Long; Madalena Pinto; Fernando Remião; Emília Sousa; Renata Silva. "Fiscalin Derivatives as Potential Neuroprotective Agents". Pharmaceutics (2022): https://doi.org/10.3390/pharmaceutics14071456.
    10.3390/pharmaceutics14071456
  13. Rita Roque Bravo; Ana Carolina Faria; Andreia Machado Brito-da-Costa; Carmo H; Premysl Mladenka; Diana Dias da Silva; Fernando Remiao; on behalf of The OEMONOM Researchers. "Cocaine: An Updated Overview on Chemistry, Detection, Biokinetics, and Pharmacotoxicological Aspects including Abuse Pattern". Toxins (2022): https://www.mdpi.com/2072-6651/14/4/278.
    10.3390/toxins14040278
  14. Ana Isabel Ribeiro; Vasyl Shvalya; Uroš Cvelbar; Renata Silva; Rita Marques-Oliveira; Fernando Remião; Helena P. Felgueiras; Jorge Padrão; Andrea Zille. "Stabilization of Silver Nanoparticles on Polyester Fabric Using Organo-Matrices for Controlled Antimicrobial Performance". Polymers (2022): https://doi.org/10.3390/polym14061138.
    10.3390/polym14061138
  15. Barbara Silva; Joana S. Rodrigues; Ana Sofia da Costa Almeida; Ana Rita Couto Machado Lima; Carla Fernandes; Guedes de Pinho P.; Joana P Miranda; Fernando Remiao. "Enantioselectivity of Pentedrone and Methylone on Metabolic Profiling in 2D and 3D Human Hepatocyte-like Cells". Pharmaceuticals (2022): https://www.mdpi.com/1424-8247/15/3/368.
    10.3390/ph15030368
  16. Ana Sofia da Costa Almeida; Barbara Silva; Guedes de Pinho P.; Fernando Remiao; Carla Fernandes. "Synthetic Cathinones: Recent Developments, Enantioselectivity Studies and Enantioseparation Methods". Molecules (2022): https://www.mdpi.com/1420-3049/27/7/2057.
    10.3390/molecules27072057
  17. Marcel Hrubša; Tomáš Siatka; Iveta Nejmanová; Marie Vopršalová; Lenka Kujovská Krcmová; Katerina Matoušová; Lenka Javorská; et al. "Biological Properties of Vitamins of the B-Complex, Part 1: Vitamins B1, B2, B3, and B5". Nutrients 14 3 (2022): 484-484. https://doi.org/10.3390/nu14030484.
    10.3390/nu14030484
  18. Bárbara Silva; Jorge Soares; Carolina Rocha-Pereira; Premysl Mladenka; Fernando Remião. "Khat, a Cultural Chewing Drug: A Toxicokinetic and Toxicodynamic Summary". Toxins (2022): https://doi.org/10.3390/toxins14020071.
    10.3390/toxins14020071
  19. Ana S. Serras; Sérgio P. Camões; Bernardo Antunes; Vera M. Costa; Flávio Dionísio; Volkan Yazar; Rui Vitorino; et al. "The Secretome of Human Neonatal Mesenchymal Stem Cells Modulates Doxorubicin-Induced Cytotoxicity: Impact in Non-Tumor Cells". International Journal of Molecular Sciences (2021): https://doi.org/10.3390/ijms222313072.
    10.3390/ijms222313072
  20. Ana Reis-Mendes; Ana Isabel Padrão; José Alberto Duarte; Salomé Gonçalves-Monteiro; Margarida Duarte-Araújo; Fernando Remião; Félix Carvalho; et al. "Role of Inflammation and Redox Status on Doxorubicin-Induced Cardiotoxicity in Infant and Adult CD-1 Male Mice". Biomolecules 11 11 (2021): 1725-1725. https://doi.org/10.3390/biom11111725.
    10.3390/biom11111725
  21. Tony Cardoso; Ana Sofia Almeida; Fernando Remião; Carla Fernandes. "Enantioresolution and Binding Affinity Studies on Human Serum Albumin: Recent Applications and Trends". Chemosensors 9 11 (2021): 304-304. https://doi.org/10.3390/chemosensors9110304.
    10.3390/chemosensors9110304
  22. Jéssica S. Barbosa; Miguel Pinto; Sandra Barreiro; Carlos Fernandes; Ricardo F. Mendes; Pedro Lavrador; Vítor M. Gaspar; et al. "Coordination Compounds As Multi-Delivery Systems for Osteoporosis". ACS Applied Materials & Interfaces (2021): https://doi.org/10.1021/acsami.1c09121.
    10.1021/acsami.1c09121
  23. Fernando Durães; Andreia Palmeira; Bárbara Cruz; Joana Freitas-Silva; Nikoletta Szemerédi; Luís Gales; Paulo Martins da Costa; et al. "Antimicrobial Activity of a Library of Thioxanthones and Their Potential as Efflux Pump Inhibitors". Pharmaceuticals 14 6 (2021): 572-572. https://doi.org/10.3390/ph14060572.
    10.3390/ph14060572
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  135. Dinis-Oliveira, R.J.; Remião, F.; Carmo, H.; Duarte, J.A.; Navarro, A.S.; Bastos, M.L.; Carvalho, F.. "Paraquat exposure as an etiological factor of Parkinson's disease". NeuroToxicology 27 6 (2006): 1110-1122. http://www.scopus.com/inward/record.url?eid=2-s2.0-33751520926&partnerID=MN8TOARS.
    10.1016/j.neuro.2006.05.012
  136. Carmo, H.; Brulport, M.; Hermes, M.; Oesch, F.; Silva, R.; Ferreira, L.M.; Branco, P.S.; et al. "Influence of CYP2D6 polymorphism on 3,4-methylenedioxymethamphetamine ('Ecstasy') cytotoxicity". Pharmacogenetics and Genomics 16 11 (2006): 789-799. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750289167&partnerID=MN8TOARS.
    10.1097/01.fpc.0000230419.05221.fc
  137. Dinis-Oliveira, R.J.; Remião, F.; Duarte, J.A.; Ferreira, R.; Sánchez Navarro, A.; Bastos, M.L.; Carvalho, F.. "P-glycoprotein induction: an antidotal pathway for paraquat-induced lung toxicity". Free Radical Biology and Medicine 41 8 (2006): 1213-1224. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749065926&partnerID=MN8TOARS.
    10.1016/j.freeradbiomed.2006.06.012
  138. Dinis-Oliveira, R.J.; Duarte, J.A.; Remião, F.; Sánchez-Navarro, A.; Bastos, M.L.; Carvalho, F.. "Single high dose dexamethasone treatment decreases the pathological score and increases the survival rate of paraquat-intoxicated rats". Toxicology 227 1-2 (2006): 73-85. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748740652&partnerID=MN8TOARS.
    10.1016/j.tox.2006.07.025
  139. Santos-Marques, M.J.; Carvalho, F.; Sousa, C.; Remião, F.; Vitorino, R.; Amado, F.; Ferreira, R.; Duarte, J.A.; de Lourdes Bastos, M.. "Cytotoxicity and cell signalling induced by continuous mild hyperthermia in freshly isolated mouse hepatocytes". Toxicology 224 3 (2006): 210-218. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745658260&partnerID=MN8TOARS.
    10.1016/j.tox.2006.04.028
  140. Dinis-Oliveira, R.J.; Sarmento, A.; Reis, P.; Amaro, A.; Remião, F.; Bastos, M.L.; Carvalho, F.. "Acute paraquat poisoning: Report of a survival case following intake of a potential lethal dose". Pediatric Emergency Care 22 7 (2006): 537-540. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746658144&partnerID=MN8TOARS.
    10.1097/01.pec.0000223179.07633.8a
  141. Capela, J.P.; Meisel, A.; Abreu, A.R.; Branco, P.S.; Ferreira, L.M.; Lobo, A.M.; Remião, F.; Bastos, M.L.; Carvalho, F.. "Neurotoxicity of ecstasy metabolites in rat cortical neurons, and influence of hyperthermia". Journal of Pharmacology and Experimental Therapeutics 316 1 (2006): 53-61. http://www.scopus.com/inward/record.url?eid=2-s2.0-29244463299&partnerID=MN8TOARS.
    10.1124/jpet.105.092577
  142. Carmo, H.; Hengstler, J.G.; Boer, D.D.; Ringel, M.; Remião, F.; Carvalho, F.; Fernandes, E.; et al. "Metabolic pathways of 4-bromo-2,5-dimethoxyphenethylamine (2C-B): Analysis of phase I metabolism with hepatocytes of six species including human". Toxicology 206 1 (2005): 75-89. http://www.scopus.com/inward/record.url?eid=2-s2.0-10044284034&partnerID=MN8TOARS.
    10.1016/j.tox.2004.07.004
  143. Carvalho, M.; Remião, F.; Milhazes, N.; Borges, F.; Fernandes, E.; Carvalho, F.; Bastos, M.L.. "The toxicity of N-methyl-a-methyldopamine to freshly isolated rat hepatocytes is prevented by ascorbic acid and N-acetylcysteine". Toxicology 200 2-3 (2004): 193-203. http://www.scopus.com/inward/record.url?eid=2-s2.0-2942714874&partnerID=MN8TOARS.
    10.1016/j.tox.2004.03.016
  144. Duarte, J.A.; Carvalho, F.; Fernandes, E.; Remião, F.; Bastos, M.L.; Magalhães, J.; Appell, H.-J.. "D-amphetamine-induced hydrogen peroxide production in skeletal muscle is modulated by monoamine oxidase inhibition". International Journal of Sports Medicine 25 6 (2004): 446-449. http://www.scopus.com/inward/record.url?eid=2-s2.0-4544278505&partnerID=MN8TOARS.
    10.1055/s-2004-820937
  145. Carvalho, M.; Remião, F.; Milhazes, N.; Borges, F.; Fernandes, E.; Do Céu Monteiro, M.; Gonçalves, M.J.; et al. "Metabolism is required for the expression of ecstasy-induced cardiotoxicity in vitro". Chemical Research in Toxicology 17 5 (2004): 623-632. http://www.scopus.com/inward/record.url?eid=2-s2.0-2442639021&partnerID=MN8TOARS.
    10.1021/tx049960f
  146. Soares, M.E.; Carvalho, M.; Carmo, H.; Remião, F.; Carvalho, F.; Batos, M.L.. "Simultaneous determination of amphetamine derivatives in human urine after SPE extraction and HPLC-UV analysis". Biomedical Chromatography 18 2 (2004): 125-131. http://www.scopus.com/inward/record.url?eid=2-s2.0-1842503142&partnerID=MN8TOARS.
    10.1002/bmc.315
  147. Carmo, H.; Hengstler, J.G.; De Boer, D.; Ringel, M.; Carvalho, F.; Fernandes, E.; Remião, F.; et al. "Comparative metabolism of the designer drug 4-methylthioamphetamine by hepatocytes from man, monkey, dog, rabbit, rat and mouse". Naunyn-Schmiedeberg's Archives of Pharmacology 369 2 (2004): 198-205. http://www.scopus.com/inward/record.url?eid=2-s2.0-10744225635&partnerID=MN8TOARS.
    10.1007/s00210-003-0850-0
  148. Carvalho, M.; Milhazes, N.; Remião, F.; Borges, F.; Fernandes, E.; Amado, F.; Monks, T.J.; Carvalho, F.; Bastos, M.L.. "Hepatotoxicity of 3,4-methylenedioxyamphetamine and a-methyldopamine in isolated rat hepatocytes: Formation of glutathione conjugates". Archives of Toxicology 78 1 (2004): 16-24. http://www.scopus.com/inward/record.url?eid=2-s2.0-1442278713&partnerID=MN8TOARS.
    10.1007/s00204-003-0510-7
  149. Remião, F.; Rettori, D.; Han, D.; Carvalho, F.; Bastos, M.L.; Cadenas, E.. "Leucoisoprenochrome-o-semiquinone formation in freshly isolated adult rat cardiomyocytes". Chemical Research in Toxicology 17 12 (2004): 1584-1590. http://www.scopus.com/inward/record.url?eid=2-s2.0-10844285575&partnerID=MN8TOARS.
    10.1021/tx049924g
  150. Carmo, H.; Boer, D.D.; Remião, F.; Carvalho, F.; Reys, L.A.D.; Bastos, M.D.L.. "Metabolism of the designer drug 4-bromo-2,5-dimethoxyphenethylamine (2C-B) in mice, after acute administration". Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 811 2 (2004): 143-152. http://www.scopus.com/inward/record.url?eid=2-s2.0-7544246357&partnerID=MN8TOARS.
    10.1016/j.jchromb.2004.08.026
  151. Soares, M.E.; Carvalho, M.; Remião, F.; Carvalho, F.; Bastos, M.D.L.. "Implementation of HPLC methodology for the quantification of malondialdehyde in cell suspensions and liver". Journal of Liquid Chromatography and Related Technologies 27 15 (2004): 2357-2369. http://www.scopus.com/inward/record.url?eid=2-s2.0-4444331498&partnerID=MN8TOARS.
    10.1081/JLC-200028139
  152. Carmo, H.; Remião, F.; Carvalho, F.; Fernandes, E.; De Boer, D.; Dos Reys, L.A.; Bastos, M.D.L.. "4-Methylthioamphetamine-induced hyperthermia in mice: Influence of serotonergic and catecholaminergic pathways". Toxicology and Applied Pharmacology 190 3 (2003): 262-271. http://www.scopus.com/inward/record.url?eid=2-s2.0-0043094096&partnerID=MN8TOARS.
    10.1016/S0041-008X(03)00190-X
  153. Remião, F.; Milhazes, N.; Borges, F.; Carvalho, F.; Bastos, M.L.; Lemos-Amado, F.; Domingues, P.; Ferrer-Correia, A.. "Synthesis and analysis of aminochromes by HPLC-photodiode array. Adrenochrome evaluation in rat blood". Biomedical Chromatography 17 1 (2003): 6-13. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037281216&partnerID=MN8TOARS.
    10.1002/bmc.203
  154. Amado, F.M.; Remião, F.; Milhazes, N.; Borges, F.; Carvalho, F.D.; Bastos, M.L.; Domingues, P.M.; Ferrer-Correia, A.J.. "Analysis of aminochromes by ESI-MS/MS determination of adrenochrome in rat blood". Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics (2002): 437-438. http://www.scopus.com/inward/record.url?eid=2-s2.0-2442651835&partnerID=MN8TOARS.
  155. Remião, F.; Carvalho, M.; Carmo, H.; Carvalho, F.; Bastos, M.L.. "Cu2+-induced isoproterenol oxidation into isoprenochrome in adult rat calcium-tolerant cardiomyocytes". Chemical Research in Toxicology 15 6 (2002): 861-869. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035998297&partnerID=MN8TOARS.
    10.1021/tx025518q
  156. Carmo, H.; De Boer, D.; Remião, F.; Carvalho, F.; Dos Reys, L.A.; De Lourdes Bastos, M.. "Identification of 4-methylthioamphetamine and some of its metabolites in mouse urine by GC-MS after acute administration". Journal of Analytical Toxicology 26 4 (2002): 228-232. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036014547&partnerID=MN8TOARS.
    10.1093/jat/26.4.228
  157. Carvalho, M.; Carvalho, F.; Remião, F.; De Lourdes Pereira, M.; Pires-Das-Neves, R.; De Lourdes Bastos, M.. "Effect of 3,4-methylenedioxymethamphetamine ("ecstasy") on body temperature and liver antioxidant status in mice: Influence of ambient temperature". Archives of Toxicology 76 3 (2002): 166-172. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036214775&partnerID=MN8TOARS.
    10.1007/s00204-002-0324-z
  158. Carvalho, F.; Fernandes, E.; Remião, F.; Gomes-Da-Silva, J.; Tavares, M.A.; Bastos, M.D.L.. "Adaptative response of antioxidant enzymes in different areas of rat brain after repeated d-amphetamine administration". Addiction Biology 6 3 (2001): 213-221. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034927677&partnerID=MN8TOARS.
    10.1080/13556210120056544
  159. Remião, F.; Carmo, H.; Carvalho, F.; Bastos, M.L.. "Letter to the editor: Cardiotoxicity studies using freshly isolated calcium-tolerant cardiomyocytes from adult rat". In Vitro Cellular and Developmental Biology - Animal 37 1 (2001): 1-4. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035234870&partnerID=MN8TOARS.
    10.1290/1071-2690(2001)037<0001:CSUFIC>2.0.CO;2
  160. Remião, F.; Carmo, H.; Carvalho, F.; Bastos, M.L.. "Copper enhances isoproterenol toxicity in isolated rat cardiomyocytes: Effects on oxidative stress". Cardiovascular Toxicology 1 3 (2001): 195-204. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035755983&partnerID=MN8TOARS.
    10.1385/CT:1:3:195
  161. Lemos-Amado, F.; Domingues, P.; Ferrer-Correia, A.; Remião, F.; Milhazes, N.; Borges, F.; Carvalho, F.D.; Bastos, M.L.. "Electrospray tandem mass spectrometry of aminochromes". Rapid Communications in Mass Spectrometry 15 24 (2001): 2466-2471. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035543079&partnerID=MN8TOARS.
    10.1002/rcm.498
  162. Carvalho, F.; Duarte, J.; Neuparth, M.; Carmo, H.; Fernandes, E.; Remião, F.; Bastos, M.. "Hydrogen peroxide production in mouse tissues after acute d-amphetamine administration. Influence of monoamine oxidase inhibition". Archives of Toxicology 75 8 (2001): 465-469. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034758492&partnerID=MN8TOARS.
    10.1007/s002040100264
  163. Remião, F.; Carmo, H.; Carvalho, F.; Bastos, M.L.. "The study of oxidative stress in freshly isolated Ca2+-tolerant cardiomyocytes from the adult rat". Toxicology in Vitro 15 4-5 (2001): 283-287. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034830263&partnerID=MN8TOARS.
    10.1016/S0887-2333(01)00022-4
  164. Remio, F.; Carmo, H.; Carvalho, F.; Bastos, M.L.. "Simultaneous determination of reduced and oxidized glutathione in freshly isolated rat hepatocytes and cardiomyocytes by HPLC with electrochemical detection". Biomedical Chromatography 14 7 (2000): 468-473. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033728344&partnerID=MN8TOARS.
  165. Remiäo, F.; Carmo, H.; Carvalho, F.D.; Bastos, M.L.. "Inhibition of glutathione reductase by isoproterenol oxidation products". Journal of Enzyme Inhibition 15 1 (1999): 47-61. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033404556&partnerID=MN8TOARS.
  166. Carvalho, F.; Fernandes, E.; Remião, F.; De Lourdes Bastos, M.. "Effect of d-amphetamine repeated administration on rat antioxidant defences". Archives of Toxicology 73 2 (1999): 83-89. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032940969&partnerID=MN8TOARS.
    10.1007/s002040050591
  167. Remiao, F.; Bastos, M.D.L.. "Potential cardiotoxic agents | Farmacos como potenciais agentes cardiotoxicos". Revista Portuguesa de Farmacia 49 2 (1999): 87-94. http://www.scopus.com/inward/record.url?eid=2-s2.0-0040366195&partnerID=MN8TOARS.
  168. Remião, F.; Bastos, M.D.L.. "O fenómeno isquemia-reperfusão e o stress oxidativo como indutores de cardiotoxicidade". Revista Portuguesa de Farmacia 48 2 (1998): 71-76. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346364582&partnerID=MN8TOARS.
  169. Bastos, M.L.; Carvalho, F.; Remião, F.; Mendes, M.E.; Ferreira, M.A.; Soares, M.E.; Timbrell, J.A.. "Changes in taurine levels in response to repeated administration of the ß2-agonist salbutamol in lambs". Journal of Veterinary Pharmacology and Therapeutics 20 1 (1997): 33-37. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031058218&partnerID=MN8TOARS.
  170. Appell, H.-J.; Duarte, J.A.; Gloser, S.; Remião, F.; Carvalho, F.; Bastos, M.L.; Soares, J.M.C.. "Administration of tourniquet: II. Prevention of postischemic oxidative stress can reduce muscle edema". Archives of Orthopaedic and Trauma Surgery 116 1-2 (1997): 101-105. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031059958&partnerID=MN8TOARS.
  171. Duarte, J.A.; Glöser, S.; Remiäo, F.; Carvalho, F.; Bastos, M.L.; Soares, J.M.C.; Appell, H.-J.. "Administration of tourniquet: I. Are edema and oxidative stress related to each other and to the duration of ischemia in reperfused skeletal muscle?". Archives of Orthopaedic and Trauma Surgery 116 1-2 (1997): 97-100. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031060012&partnerID=MN8TOARS.
  172. Carvalho, F.; Remião, F.; Soares, M.E.; Catarino, R.; Queiroz, G.; Bastos, M.L.. "d-Amphetamine-induced hepatotoxicity: Possibie contribution of catecholamines and hyperthermia to the effect studied in isolated rat hepatocytes". Archives of Toxicology 71 7 (1997): 429-436. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030927810&partnerID=MN8TOARS.
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Preface / Postscript
  1. Faculdade de Psicologia e de Ciências da Educação. "Promovendo a Excelência Pedagógica da Universidade / Fostering Pedagogical Excellence in the University". Preface to EDUCAÇÃO SOCIEDADE E CULTURA: reflexões interdisciplinares, 5-8. Porto, Portugal: Edições Afrontamento. 2011.
    Published
Thesis / Dissertation
  1. Remião, Fernando Manuel Gomes. "Cardiotoxicidade do isoproterenol e dos produtos da sua oxidação : Estudos mecanísticos em suspensões de cardiomiócitos isolados de rato adulto". PhD, 2002. http://hdl.handle.net/10216/9849.
Activities

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2022 - Current Physiologically relevant cellular systems for predicting the bioavailability of dry powder inhalation products
Co-supervisor
 Química Farmacêutica (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2021 - Current Modulation of P-glycoprotein expression/activity at kidney level: a new therapeutic strategy to reduce cisplatin-induced nephrotoxicity
Co-supervisor of Jéssica Patrícia Veiga Matos
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2021 - Current Improving Edaravone's mitochondrial targeting using cationic smart carriers: a novel therapeutic approach
Co-supervisor of Sandra Filipa Carvalho Barreiro
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2020 - Current Dual-acting drugs targeting Ferroptosis and COMT: a new potential therapeutic strategy to fight Parkinson's Disease
Co-supervisor of Vera Lúcia Santos Silva
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/03 - Current Enantioselective studies of promethazine and its metabolites: chemical and toxicology approaches
Co-supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/03 - Current Using a nanomedicine-based approach as a second chance for tolcapone.
Co-supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/03 - Current Phenethylamine derivatives: new insights on their pharmacological and toxicological profile
Co-supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2016/07 - Current Design of new inducers/activators of ABC transporters: An innovative strategy to fight Alzheimer's disease
Supervisor
 Pós-Doutoramento (Other)
Universidade do Porto Faculdade de Farmácia, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2021 - 2022 Semi-preparative enantioresolution, racemization and enantioselectivity studies with MDPV and binding affinity studies with synthetic cathinones
Co-supervisor of Ana Sofia da Costa Almeida
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2021 - 2022 In vitro study of Innovative Antiparkinsonian agents: evaluation of their toxicological profile and neuroprotective potential
Co-supervisor
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2021 - 2022 Development of lipid-based nanosystems (SLN and NLC) for nose-to-brain delivery: a potential strategy for the treatment of neurodegenerative diseases
Co-supervisor of José Miguel Rodrigues Pereira
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2021 - 2022 Spermatogenesis protection by P-Glycoprotein modulation
Co-supervisor of Maria Sousa Dias
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2021 - 2022 Combination effects of polycyclic aromatic hydrocarbons (PAH) ubiquitous in the environment – A metabolomics approach
Co-supervisor of Vânia Raquel da Cunha Monteiro
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2021 - 2022 Alzheimer's disease: unraveling the biological activity of novel synthetic compounds targeting tau hyperphosphorylation and the amyloid-beta pathway
Co-supervisor of Ana Rita Pinto Monteiro
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/09 - 2022 Estudos toxicocinéticos com indutores/ativadores dos transportadores de efluxo membranares (glicoproteína-P)
Supervisor
 Pós-Doutoramento (Other)
Universidade do Porto Faculdade de Farmácia, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2018 - 2021 Pentedrona e Metilona; Enantiorresolução e Enantiosseletividade; Toxicocinética e toxicodinâmica; In vitro
Supervisor
 Farmacologia e Toxicologia Experimentais e Clínicas (associação) (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2015/09 - 2020/01/17 Development of new chemical entities based on natural scaffolds with therapeutic potential towards age-related disorders
Co-supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2019 - 2020 Interindividual variability in ABCB1 expression in human Sertoli cells
Co-supervisor
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2019 - 2020 Mecanismos de reconhecimento molecular e determinação da afinidade de ligação de catinonas sintéticas à albumina sérica humana, por cromatografia de afinidade de alta eficiência
Co-supervisor
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2019 - 2020 Evaluation of P-Glycoprotein Expression/Activity in HK2 Cells
Supervisor of Jéssica Patrícia Veiga Matos
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2019 - 2020 Innovative Microsampling Approach For The Analysis of Methadone by HPLC-ED
Co-supervisor
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2016/05 - 2019/07 New Technologies for three Health Challenges of Modern Societies: Diabetes, Drug Abuse and Kidney Diseases (DESignBIOtecHealth). Task 3: Exploratory ADME & Safety
Supervisor
 Pós-Doutoramento (Other)
Universidade do Porto Faculdade de Farmácia, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2013/09 - 2018/07/16 Design and development of multi-target agents for neurodegenerative diseases
Co-supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2013/09 - 2018/07/11 Development of PEGylated platforms to overcome blood-brain barrier constraints in neurodegenerative therapy
Co-supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2011/09 - 2016/07/08 Hidroxycinnamic Acid, a Valid Scaffold for the Development of CNS Multitarget Drugs. Synthesis, Pharmacological and Toxicological Studies.
Co-supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2014/06 - 2016/06 Biological studies of new inducers and activators of ABC Transporters
Supervisor
 Pós-Doutoramento (Other)
Universidade do Porto Faculdade de Farmácia, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2015 - 2016 Separação enantiomérica de derivados catinónicos em drogas de abuso por HPLC quiral - Estudo da citotoxidade dos enantiómeros da 3,4- metilenodioxipirovalerona (MDPV)
Supervisor
 Ciências Forenses (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2015 - 2016 Estudo da Permeabilidade da TX5 em Caco-2 e RBE4 - um Potencial indutor/activador da Glicoproteína-P
Supervisor
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2011 - 2015 Mechanisms of Regulation of P-glycoprotein and Breast Cancer Resistance Protein at the Blood-Brain Barrier: Focus on the Role of Mhorphine, and P-glycoprotein Activation
Supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2010/01 - 2014/12 Cardiac and neurologic toxicity of Mitoxantrone using in vitro, in vivo models and clinical studies. Relevance to the side effects observed in cancer and multiple sclerosis mitoxantrone treated patients
Co-supervisor
 Pós-Doutoramento (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 - 2014 Estudo da Glicoproteína-P em Linfócitos T Humanos e em Plasma de Ratos Charles Rivers usando a TX5 como Potencial Indutor da sua Expressão e Actividade
Supervisor
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2014 - 2014 Comparison of Paraquat Cytotoxicity in Cell Cultures: Caco-2 AND RBE4
Supervisor
 Toxicologia Analítica Clínica e Forense (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2011/02 - 2013/02 Effects of exercise training on endothelial progenitor cells in coronary artery disease patients recovering from an acute myocardial infarction
Co-supervisor
 Pós-Doutoramento (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2013 - 2013 Relatórios de Estágio realizado na Farmácia Cristo Rei e no The Whittington Hospital ­ Londres
Co-supervisor
 Ciências Farmacêuticas (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2007 - 2013 Development and application of antidotes for the treatment of xenobiotic intoxications in pre-clinical and clinical studies using the model of paraquat-induced pulmonary toxicity
Co-supervisor
 Pós-Doutoramento (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2006/01 - 2009/03/11 Interacções toxicológicas entre o álcool e a ecstasy. Estudos in vivo e in vitro.
Co-supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2009 - 2009 The cardiotoxicity of mitoxantrone: a mechanistic approach using in vitro and in vivo models.
Supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2006 - 2006 Screening of P-Glycoprotein Inducers and Activators as Effective Antidotes Against its Toxic Substrates in Caco-2 Cells. The Example of Paraquat
Supervisor
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2005 - 2006 Desenvolvimento de uma metodologia de HPLC para a detecção de aductos das catecolaminas com a GSH em amostras biológicas
Supervisor
 Mestrado em Toxicologia (Master)
Universidade de Aveiro, Portugal
2005 - 2005 Oxidative Stress in Heart Disease: Role of Catecholamines and Metals. in Vitro and Clinical Studies
Supervisor
 Toxicologia (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2014/06 - 2018/06 Responsável pela organização regular de cursos, seminários e workshops de formação pedagógica para a docência no Ensino Superior na Universidade do Porto https://inovacaopedagogica.up.pt/42-2/formacao/cursos/ (2014/06 - 2018/06)
Workshop
 Universidade do Porto, Portugal
2015/09/13 - 2015/09/16 51.º Congresso das Sociedades Europeias de Toxicologia "Bridging Sciences for Safety" é o lema do 51.º Congresso das Sociedades Europeias de Toxicologia, que se realizará em Portugal, na cidade do Porto, entre os dias 13 e 16 de setembro 2015. O evento, onde são aguardados mais de 1.500 delegados da Europa e de outros países, vai ser organizado em parceria com a Sociedade Portuguesa de Farmacologia. O Congresso é presidido por Félix Carvalho, professor da Faculdade de Farmácia da Universidade do Porto. (2015/09/13 - 2015/09/16)
Congress (Member of the Organising Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal

EUROTOX, Belgium
2014/09/05 - 2014/09/05 Primeiro Congresso Nacional de Práticas Pedagógicas no Ensino Superior https://cnappes.org/cnappes-2014/ (2014/09/05 - 2014/09/05)
Congress (President of the Organising Committee)
 Universidade do Porto, Portugal

Committee member

Activity description
Role 		Institution / Organization
2023/01 - Current Membro do Conselho de Representantes da FFUP
Member
 Universidade do Porto Faculdade de Farmácia, Portugal
2020/11 - Current Membro da Comissão de Acompanhamento de Curso - Mestrado em Toxicologia Analítica Clínica e Forense
Member
 Universidade do Porto Faculdade de Farmácia, Portugal
2020/11 - Current Membro da Comissão Cientifica - Mestrado em Toxicologia Analítica Clínica e Forense
Member
 Universidade do Porto Faculdade de Farmácia, Portugal
2020/03/11 - Current Coordenador da Task-Force para a dinamização do Ensino à Distância na Faculdade de Farmácia da U.Porto, no contexto do plano de contingência do Covid-19
Coordinator
 Universidade do Porto Faculdade de Farmácia, Portugal
2019/05 - Current Director de Curso de Mestrado Integrado - Mestrado Integrado em Ciências Farmacêuticas
President / Vice-president
 Universidade do Porto Faculdade de Farmácia, Portugal
2014 - Current Membro da Comissão Coordenadora do Congresso Nacional de Práticas Pedagógicas no Ensino Superior (CNaPPES)
Member
2012 - Current Membro da Comissão Científica que organiza anualmente o "Congreso Internacional de Docencia Universitaria (CINDU)"
Member
 Universidade de Vigo, Spain
2002 - Current Membro do Conselho Cientifico da FFUP
Member
 Universidade do Porto Faculdade de Farmácia, Portugal
2017/03/14 - 2021/03/13 MC Member at COST Action - CA16113 - CliniMARK: ‘good biomarker practice’ to increase the number of clinically validated biomarkers.
Member
 European Cooperation in Science and Technology, Belgium

Journal scientific committee

Journal title (ISSN) Publisher
2017/04/17 - Current Toxicology and Applied Pharmacology (1096-0333) Elsevier

Other jury / evaluation

Activity description Institution / Organization
2022 - 2022 Membro do Júri do Prémio Inovação Pedagógica 2022 do Departamento das Ciências Farmacêuticas e do Medicamento da Faculdade de Farmácia da Universidade de Lisboa
2020 - 2020 Membro do Júri do Prémio em Excelência Pedagógica da Universidade de Coimbra Universidade de Coimbra, Portugal
2020 - 2020 Membro do Júri do Concurso "Unidades Curriculares InovPed" https://inovacaopedagogica.up.pt/42-2/excelencia-pedagogica/inovped-2/ Universidade do Porto, Portugal
2018 - 2019 Membro do Júri do Prémio em Excelência Pedagógica da Universidade do Porto Universidade do Porto, Portugal
2018 - 2018 Presidente do Júri do Concurso "Unidades Curriculares InovPed" https://inovacaopedagogica.up.pt/42-2/excelencia-pedagogica/inovped-2/ Universidade do Porto, Portugal
2016 - 2017 Presidente do Júri do Prémio "Projetos de Inovação Pedagógica" da Universidade do Porto https://inovacaopedagogica.up.pt/42-2/excelencia-pedagogica/projetos-inovacao-pedagogica/ Universidade do Porto, Portugal
2014 - 2017 Presidente do Júri do Prémio em Excelência Pedagógica da Universidade do Porto Universidade do Porto, Portugal
2014/04 - 2014/04 Membro do Júri do Concurso "Partilha e Divulgação de Experiências no Ensino da Inovação no Ensino Superior Português". A Fundação para a Ciência e a Tecnologia, I. P., com a colaboração da Direção-Geral do Ensino Superior, lançou, em abril de 2014, um concurso público para financiamento de projetos que visassem a partilha e a divulgação de experiências de inovação didática no ensino superior português. Foram apresentadas 181 candidaturas, tendo sido propostos para financiamento 35 projetos e concluídos 33. Fundação para a Ciência e a Tecnologia, Portugal
2012 - 2013 Membro do Júri do Prémio em Excelência Pedagógica da Universidade do Porto Universidade do Porto, Portugal
Distinctions

Award

2008 Prémio de Excelência em e-Learning 2006/7 da U.Porto
Universidade do Porto, Portugal
1998 Primeiro Prémio no concurso “Prémios UCB de Farmacologia - Edição de 1998”
Sociedade Portuguesa de Farmacologia, Portugal

Other distinction

2005 Creditação como Pessoa Competente para a Prática de Experimentação Animal
Direcção-Geral de Alimentação e Veterinária, Portugal
1996 Menção honrosa no concurso “Prémios UCB de Farmacologia - Edição de 1996”
Sociedade Portuguesa de Farmacologia, Portugal