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Philip Guilherme Capelo O Toole. Completed the Mestrado in Bioquímica in 2021/02/04 by Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia and Licenciatura in Bioquímica in 2018/07/14 by Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia. Published 1 articles in journals. Participated in 5 event(s). Works in the area(s) of Natural sciences with emphasis on Biological Sciences with emphasis on Biochemistry.
Identification

Personal identification

Full name
Philip Guilherme Capelo OToole

Citation names

  • Philip O'Toole

Author identifiers

Ciência ID
D01C-E52C-652E
ORCID iD
0000-0002-4995-7255

Email addresses

  • p.otoole@campus.fct.unl.pt (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English (Mother tongue)
Education
Degree Classification
2021/11/01 - 2025/11/01
Ongoing
 Doctoral Program in Chemistry (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2018/09/10 - 2021/02/04
Concluded
 Bioquímica (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"An NMR insight into the liquid-liquid phase separation of FUS Grade: 19/20" (THESIS/DISSERTATION)
 18
2015/09/20 - 2018/07/14
Concluded
 Bioquímica (Licenciatura)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Crowding Effects on Protein Structure and Functionality" (THESIS/DISSERTATION)
 17
Affiliation

Science

Category
Host institution 		Employer
2020/07/26 - 2020/10/24 Researcher (Research) REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Projects

Grant

Designation Funders
2021/11/01 - 2025/11/01 Development of 19F/B-complexes probes for 19F NMR structural studies of protein liquid phase separation
2021.05564.BD
PhD Student Fellow
Fundação para a Ciência e a Tecnologia
Ongoing
2020/07/26 - 2020/10/24 Aplicação de técnicas de RMN ao estudo de separação de fases líquido-líquido de proteínas
Escola de Verão UCIBIO
Research Fellow
REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Conference abstract
  1. Barreiro, Daniela S.; Favinha, André G.; Martins, Joana N. ; Philip O'Toole; Pauleta, Sofia R.. Corresponding author: Pauleta, Sofia R.. "Hemoglobin-Acrylamide Adduct - A Spectroscopy Study". Paper presented in XXVI Encontro Nacional da Sociedade Portuguesa de Química, Porto, 2019.
Conference poster
  1. Silva, Micael S.; Viegas, Aldino; Philip O'Toole; Figueiredo, Angelo M; Cabrita, Eurico J.. "Choline glutamate modulates protein folding and stability: an NMR view". Paper presented in 2020 CCPN Conference online, 2020.
  2. Micael S. Silva; Philip O'Toole; Aldino Viegas; Angelo M. Figueiredo; Eurico J. Cabrita. "Choline glutamate modulates protein folding and stability: an NMR view (Presented by Micael S. Silva)". Paper presented in 2020 CCPN Conference online, 2020.
  3. André G. Favinha; Daniela S. Barreiro; Joana N. Martins; Philip O'Toole; Sofia R. Pauleta. "Acrylamide-hemoglobin adduct: a spectroscopic study (Presented by Joana N. Martins)". Paper presented in XXVI Encontro Nacional da SPQ, 2019.
  4. Barreiro, Daniela S.; Favinha, André G.; Martins, Joana N. ; Philip O'Toole; Pauleta, Sofia R.. Corresponding author: Pauleta, Sofia R.. "Hemoglobin-Acrylamide Adduct - a Spectroscopic Study". Paper presented in XXVI Encontro Nacional da Sociedade Portuguesa de Química, 2019.
  5. Micael S. Silva; Philip O'Toole; Aldino Viegas; Angelo M. Figueiredo; Eurico J. Cabrita. "Modulation of protein (de)stabilization by ionic liquids: an NMR view (Presented by Micael S. Silva)". Paper presented in 21th ISMAR - 15th EUROMAR joint conference, 2019.
  6. Philip O'Toole; Filipa Marcelo; Eurico Cabrita. "Characterization of crowding effects on protein structure and functionality (Presented by Philip O'Toole)". Paper presented in VIII Ibero-American NMR Meeting, 2018.
  7. Micael S. Silva; Philip O'Toole; Aldino Viegas; Angelo M. Figueiredo; Eurico J. Cabrita. "Tuning protein stability with ionic liquids: investigation of destabilizing vs stabilizing effects (Presented by Micael S. Silva)". Paper presented in 28th ICMRBS - International Conference on Magnetic Resonance in Biological Systems, 2018.
Journal article
  1. Favinha, A.G.; Barreiro, D.S.; Martins, J.N.; O'Toole, P.; Pauleta, S.R.. "Acrylamide-hemoglobin adduct: A spectroscopic study". Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy 241 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85087110236&partnerID=MN8TOARS.
    10.1016/j.saa.2020.118644
Preprint
  1. Sara S. Félix; Philip O’Toole; Nuno A. S. Oliveira; Brígida R. Pinho; Thomas S. Blacker; Fábio Fernandes; Jorge M. A. Oliveira; et al. "Pathological mutation in SMN impairs modulation of GAR1 phase separation linking condensate dysfunction to Spinal Muscular Atrophy". 2025. https://doi.org/10.1101/2025.01.30.635772.
    10.1101/2025.01.30.635772
Activities

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2024/05/09 - 2024/05/10 4th Meeting of Young Biophysicists (2024/05/09 - 2024/05/10)
Conference (Member of the Organising Committee)
 Universidade da Beira Interior, Portugal
2023/06/01 - 2023/06/02 3rd Meeting of Young Biophysicists (2023/06/01 - 2023/06/02)
Conference (Member of the Organising Committee)
 Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/06/03 - 2022/06/03 2nd Meeting of Young Biophysicists (2022/06/03 - 2022/06/03)
Conference (Member of the Organising Committee)
 Universidade de Aveiro, Portugal
2018/06/26 - 2018/06/29 Assisted in the organization of VIII Ibero-American NMR Meeting - 6th Iberian NMR Meeting - 9th GERMN Meeting - 4th Portuguese RNRMN Meeting (2018/06/26 - 2018/06/29)
Conference (Member of the Organising Committee)
 Universidade Nova de Lisboa, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023/06/18 - 2023/06/23 NMR course in XV “Manuel Rico” NMR Summer School The course consisted of 24 hours of specialized classes on NMR Spectroscopy
Workshop
 XV “Manuel Rico” NMR Summer School
Universidad de Zaragoza, Spain
2023/03/06 - 2023/03/10 Attended the 5th GNMR school, which was held in Heinrich Heine University of Düsseldorf during March 6-10, 2023 Attended a total of 35 hours of tutorial talks/exercise sessions/application-oriented talks
Workshop
 5th GNMR school
Heinrich-Heine-Universität Düsseldorf, Germany
2022/09/12 - 2022/09/16 Participated in the ’Barcelona Protein Aggregation Training School’ on 12-16 September 2022
Workshop
 Barcelona Protein Aggregation Training School
Universitat Autònoma de Barcelona Institut de Biotecnologia i de Biomedicina, Spain
2022/04/18 - 2022/04/22 Attended the PhasAGE Training School “Biomolecular condensates in cell function, aging and disease” held on 18 - 22 April 2022 at i3S - Instituto de Investigação e Inovação em Saúde, with an approximate duration of 35 hours
Workshop
 Biomolecular condensates in cell function, aging and disease
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020/07/26 - 2020/10/24 During the UCIBIO "Verão com Ciência" workshop. The participant carried out experimental research and orally presented in a symposium.
Workshop
 Verão com Ciência 2020
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/10/15 - 2020/01/07 Massive Open Online Course: Nuclear Magnetic Resonance a Compass to Nanoworld - session 3
Workshop
 Nuclear Magnetic Resonance a Compass to Nanoworld - session 3
Université de Lille, France
2019/09/04 - 2019/09/06 I NOVA Biophysica International Conference
Conference
 I NOVA Biophysica International Conference
Universidade Nova de Lisboa, Portugal
2019/07/24 - 2019/07/26 XXVI Encontro Nacional da Sociedade Portuguesa da Química
Conference
 XXVI Encontro Nacional da Sociedade Portuguesa da Química
Universidade do Porto Faculdade de Ciências, Portugal
2018/10/18 - 2018/10/19 ESOR/Champalimaud ASKLEPIOS Symposium Imaging Hallmarks of Cancer
Conference
 Imaging Hallmarks of Cancer
Fundação Champalimaud, Portugal
2018/06/26 - 2018/06/29 VIII Ibero-American NMR Meeting
Conference
 VIII Ibero-American NMR Meeting
Universidade Nova de Lisboa, Portugal