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Biologist and researcher in the field of Systems Biology. Holds a Bachelor of Science degree in Biology (branch of Molecular Biology and Genetics, with a minor in Informatics) from the Faculty of Sciences of the University of Lisbon and a Master of Science degree in Biotechnology from the NOVA School of Science and Technology of NOVA University Lisbon. His scientific interests concern the usage of molecular and computational tools in the modelling of complex biological systems and the study of their relation with human health and heredity. Has research experience in the field of epigenetics and gene regulation, and metabolomics, and has collaborated with the private sector in the improvement of vaccine production through biochemical modelling and deep learning techniques.
Identification

Personal identification

Full name
MÁRIO GIL POIARES RODRIGUES DE OLIVEIRA

Citation names

  • Gil P. Oliveira
  • Mário Gil Poiares Rodrigues de Oliveira
  • Gil Poiares-Oliveira

Author identifiers

Ciência ID
D019-5596-42E2
ORCID iD
0000-0003-4638-2879
Google Scholar ID
IvGHLzkAAAAJ
Researcher Id
AAE-9440-2021
Scopus Author Id
57932405100

Email addresses

  • gil.oliveira@tecnico.ulisboa.pt (Professional)

Telephones

Telephone
  • (+351) 213100300 Ext.: 2318 (Professional)

Addresses

  • Room 401, INESC-ID, Rua Alves Redol, 9, 1000-029, Lisboa, Lisboa, Portugal (Professional)

Websites

Knowledge fields

  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Genetics and Heredity
  • Engineering and Technology - Industrial Biotechnology
  • Medical and Health Sciences - Medical Biotechnology
  • Exact Sciences - Computer and Information Sciences - Bioinformatics
  • Medical and Health Sciences - Medical Biotechnology - Gene-based Diagnostics and Therapeutic Interventions
  • Medical and Health Sciences - Basic Medicine - Human Genetics
  • Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
French Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2019/09 - 2022/06/28
Concluded
Biotecnologia (Mestrado)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Development of a novel hybrid genome-scale modelling method and showcase with HEK293 cell cultures" (THESIS/DISSERTATION)
16
2016/09 - 2019/06/21
Concluded
Biologia (Licenciatura)
Major in Biologia Molecular e Genética com Minor em Informática
Universidade de Lisboa Faculdade de Ciências, Portugal
14
Affiliation

Science

Category
Host institution
Employer
2022/09/07 - 2023/03/31 Research Trainee (Research) Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
Universidade de Lisboa Faculdade de Ciências, Portugal
2021/01 - 2022/07/31 Researcher (Research) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2020/08/25 - 2020/12 Research Trainee (Research) Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Universidade de Lisboa Faculdade de Medicina, Portugal

Other Careers

Category
Host institution
Employer
2023/06/05 - Current Técnico Superior (Técnico Superior) Instituto de Engenharia de Sistemas e Computadores Investigação e Desenvolvimento em Lisboa, Portugal
Universidade de Lisboa Instituto Superior Técnico, Portugal
(...)

Others

Category
Host institution
Employer
2017 - 2018/01 Membro do Departamento de Gestão de Projetos - Ciências da Vida Júnior Empresa Ciências, Portugal
Projects

Grant

Designation Funders
2021/10/01 - 2022/03/31 SILICOMEDIA - In silico culture or feed media design based on prior metabolic knowledge: Application to the Production phase of a mammalian cell line
LAQV/BI/006/2021
Research Fellow
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade Nova de Lisboa Departamento de Química, Portugal
GlaxoSmithKline Biologicals SA
Concluded
Outputs

Publications

Conference poster
  1. Estima, Cláudia; Marques, Madalena; Gil Poiares-Oliveira; Ana Espada de Sousa; Gama-Carvalho, Margarida. Corresponding author: Estima, Cláudia. "Dissecting the role of miR-34c-5p in Human CD4+ T cells". Paper presented in XLVIII Annual Meeting of the Portuguese Society for Immunology, 2023.
  2. Estima, Cláudia; Marques, Madalena; Gil Poiares-Oliveira; B. Farias, Guilherme; Ana E Sousa; Gama-Carvalho, Margarida. Corresponding author: Estima, Cláudia. "The impact of miR-34c-5p on the transcriptome of Human CD4+ T cells". Paper presented in RNA in Disease - IX ptRNA Meeting, 2023.
Journal article
  1. Ramos, João R. C.; Pinto, José; Gil Poiares-Oliveira; Peeters, Ludovic; Dumas, Patrick; Oliveira, Rui. Corresponding author: Oliveira, Rui. "Deep hybrid modeling of a HEK293 process: Combining long short-term memory networks with first principles equations". Biotechnology and Bioengineering (2024): http://dx.doi.org/10.1002/bit.28668.
    Open access • Published • 10.1002/bit.28668
  2. Ramos, João R. C.; Gil P. Oliveira; Dumas, Patrick; Oliveira, Rui. "Genome-scale modeling of Chinese hamster ovary cells by hybrid semi-parametric flux balance analysis". Bioprocess and Biosystems Engineering (2022): http://dx.doi.org/10.1007/s00449-022-02795-9.
    10.1007/s00449-022-02795-9
Thesis / Dissertation
  1. "Development of a HEK293 Cell-line Digital Twin Based on Hybrid Semi-Parametric Modeling at the Genome-Scale". Master, Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, 2022. https://hdl.handle.net/10362/142477.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/09/13 Development of a HEK293 Cell-line Digital Twin Based on Hybrid Semi-Parametric Modeling at the Genome-Scale GSK Vaccines Staff Meeting
GlaxoSmithKline Biologicals SA (Rixensart, Belgium)
2022/02 Development of a HEK293 Cell-line Digital Twin Based on Hybrid Semi-Parametric Modeling at the Genome-Scale Jornadas de Investigação do DQ e DCV
Departamentos de Química e Ciências da Vida da NOVA School of Science and Technology (Caparica, Portugal)

Association member

Society Organization name Role
2017 - 2019/06 AEFCL - Associação dos Estudantes da Faculdade de Ciências de Lisboa Membro da Direção

Committee member

Activity description
Role
Institution / Organization
2016 - 2019/09 Conselho Pedagógico da Licenciatura em Biologia
Member
Universidade de Lisboa Faculdade de Ciências, Portugal
2016/09 - 2019/06 Comissão de Curso da Licenciatura em Biologia
Member
Universidade de Lisboa Faculdade de Ciências, Portugal
2018 - 2019 Conselho de Escola
Member
Universidade de Lisboa Faculdade de Ciências, Portugal
2018 - 2019 Comissão ad-hoc de Boas Práticas Pedagógicas
Member
Universidade de Lisboa Faculdade de Ciências, Portugal
2018 - 2018 Conselho Pedagógico
Member
Universidade de Lisboa Faculdade de Ciências, Portugal
Distinctions

Other distinction

2019 Membro Graduado da Ordem dos Biólogos
Ordem dos Biólogos, Portugal