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I am a PhD student at João Barata's Laboratory at the Instituto de Medicina Molecular-João Lobo Antunes (IMM-JLA) in Lisbon since 2020. My main goal is to study the aberrant IL-7R signaling in leukemogenesis. I have a bachelor's in Biomedical Sciences by University of Algarve (2011-2014) and a master's degree in Biopharmaceutical Sciences by Faculty of Pharmacy University of Lisbon (2014-2016). My main expertises include molecular biology, cell culture, histology, flow cytometry and animal models (Felassa B). My main scientific topic is Hemato-oncobiology.
Identification

Personal identification

Full name
Ana Patrícia Cebola Cachucho

Citation names

  • Cachucho, Ana

Author identifiers

Ciência ID
D013-F1F4-DB01
ORCID iD
0000-0003-4815-1687

Email addresses

  • anacachucho@medicina.ulisboa.pt (Professional)

Knowledge fields

  • Medical and Health Sciences - Basic Medicine
  • Natural sciences - Biological Sciences
  • Medical and Health Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Intermediate (B1) Upper intermediate (B2) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2020/01/01 - 2024/01/01
Ongoing
 Ciências Biomédicas (Doutoramento)
Universidade de Lisboa Faculdade de Medicina, Portugal
2014/10/06 - 2016/11/02
Concluded
 Ciências Biofarmacêuticas (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Characterization of the mechanism of action of two compounds with bone formation properties" (THESIS/DISSERTATION)
 17/2o
2011/09/12 - 2014/07/08
Concluded
 Ciências Biomédicas (Licenciatura)
Universidade do Algarve, Portugal
""Histological characterization of knockout mice for Grp gene"" (THESIS/DISSERTATION)
 15/20
Affiliation

Science

Category
Host institution 		Employer
2017/02/01 - 2019/12/31 Research Assistant (Research) Instituto de Medicina Molecular, Portugal
Instituto de Medicina Molecular, Portugal
2014/05/01 - 2014/07/31 Research Trainee (Research) Universidade do Algarve, Portugal
Centro de Ciências do Mar, Portugal

Others

Category
Host institution 		Employer
2015/09/01 - 2016/11/02 MSc Student TechnoPhage SA, Portugal
TechnoPhage SA, Portugal
(...)
Projects

Grant

Designation Funders
2019/09/01 - 2019/12/31 "IL-7/IL-7R signaling networks in health and malignancy"
info:eu-repo/grantAgreement/EC/H2020/648455/EU
Research Fellow
European Research Council
Ongoing
2017/02/01 - 2019/09/30 "Aberrant IL7R signaling in leukemogenesis: from the basics to potential therapeutics"
FAPESP/20015/2014
Research Fellow
Instituto de Medicina Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2019/01/01 - 2019/12/31 Instituto de Medicina Molecular - IMM
UID/BIM/50005/2019
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Conference poster
  1. Cachucho, Ana; Corrêa, Juliana Ronchi; Amaral, Patrícia; Araújo, Tatiana F.; Fernandes, Marta B.; Euzébio, Mayara; João L. Neto; et al. "Characterizing the risk for IL-7R-mediated malignancy in different stages of hematopoietic development". Paper presented in XLVIII Annual Meeting of Sociedade Portuguesa de Imunologia, 2023.
  2. Fazenda, Cindy*; Vitorino, Marta*; Cachucho, Ana; Shu-Wha, L; Gavaia, PJ; Conceição, Natércia; Cancela, ML. "Gla-rich protein deficient mice born from homozygous mutant progenitors show cartilage and bone defects". Paper presented in XL Jornadas Portuguesas de Genética, Coimbra, Portugal, 2016.
    Assistant staff
Journal article
  1. Almeida, Afonso R. M.; Neto, João L.; Cachucho, Ana; Euzébio, Mayara; Meng, Xiangyu; Kim, Rathana; Fernandes, Marta B.; et al. "Interleukin-7 receptor a mutational activation can initiate precursor B-cell acute lymphoblastic leukemia". Nature Communications 12 1 (2021): http://dx.doi.org/10.1038/s41467-021-27197-5.
    Published • 10.1038/s41467-021-27197-5
  2. Silva, Ana Patricia; Almeida, Afonso R.M.; Cachucho, Ana; Neto, João L; Demeyer, Sofie; Ramos de Matos, Mafalda; Hogan, Thea; et al. "Overexpression of wild type IL-7Ra promotes T-cell acute lymphoblastic leukemia/lymphoma". Blood (2021): http://dx.doi.org/10.1182/blood.2019000553.
    10.1182/blood.2019000553
Thesis / Dissertation
  1. Cachucho, Ana. "Characterization of the mechanism of action of two compounds with bone formation properties". Master, Universidade de Lisboa Faculdade de Farmácia, 2016.
  2. Cachucho, Ana. "Histological characterization of knockout mice for Grp gene". Degree, Universidade do Algarve, 2014.
Activities

Association member

Society Organization name Role
2012/12/01 - 2014/01/31 Biomedical Sciences Student Association at University of Algarve Secretary of the General Meeting Board