Maria Inês Costa de Sousa (CB1A-2C81-A5B4)

Curriculum Vitae

Maria Inês Costa de Sousa

Maria Inês Costa de Sousa completed her BSc in Biomedical Sciences in 2018. After finishing her BSc, Maria has worked as a Laboratory Technician at Morinha Lab - Laboratório de Biodiversidade e Genética Molecular. Maria did her MSc in Biotechnology at Universidade de Aveiro and for her master's disseration Maria worked at the Single Molecule Microbiology Lab, at ITQB. Maria was a Research Trainee in Universidade de Aveiro CICECO and now a PhD Student and has received 3 awards and/or honors. Her work focuses on the production and clarification of mRNA using thermorreversible aqueous biphasic systems and ionic liquids. Maria I. Sousa has experience on in vitro transcription for mRNA production, agarose gel eletrophoresis, Dot-blot analysis, chromatography, PCR and thermorreversible aquouse biphasis system phase separation with Ionic liquids as adjuvants.

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Identification

Personal identification

Full name: Maria Inês Costa de Sousa
Date of birth: 1997/05/15
Gender: Female

Citation names

Sousa, Maria I.

Author identifiers

Ciência ID: CB1A-2C81-A5B4

Knowledge fields

Engineering and Technology - Industrial Biotechnology
Natural sciences - Biological Sciences - Molecular Biology
Natural sciences - Biological Sciences - Microbiology

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese (Mother tongue)
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)

Education

	Degree	Classification
2019 - 2021 Concluded	Mestrado em Biotecnologia (Mestrado) Major in Biotecnologia Molecular Universidade de Aveiro, Portugal "Improved Techniques for Single-Molecule mRNA Detection and Tracking in Living Escherichia coli Cells" (THESIS/DISSERTATION)	17/20
2015 - 2018 Concluded	Licenciatura em Ciências Biomédicas (Licenciatura) Universidade de Aveiro, Portugal	16/20

Affiliation

Science

	Category Host institution	Employer
2022/05 - 2023/07	Research Trainee (Research)	Universidade de Aveiro CICECO, Portugal
	Universidade de Aveiro CICECO, Portugal

Others

	Category Host institution	Employer
2023/08 - Current	PhD Student	Universidade de Aveiro CICECO, Portugal

2018 - 2019	Laboratory Technician	Morinha Lab- Laboratório de Biodiversidade e Genética Molecular, Portugal

Projects

Grant

	Designation	Funders
2022 - Current	mVACCIL- Improving the manufacturing of mRNA vaccines applying ionic liquids and integrated production-clarification processes EXPL/BII-BTI/0731/2021 Research Fellow Universidade de Aveiro CICECO, Portugal	Ongoing

Outputs

Publications

Conference poster

Sousa, Maria I.. "Improving the manufacturing of mRNA with thermoreversible aqueous biphasic systems and ionic liquids". Paper presented in Jornadas CICECO 2025, 2025.
Sousa, Maria Inês. "Improving the manufacturing of mRNA vaccines with an integrated production-clarification process". Paper presented in mRNA Health Conference, 2024.
Sousa, Maria Inês. "Improving the manufacturing of mRNA vaccines with an integrated production-clarification process". Paper presented in Jornadas CICECO 2024, 2024.
Sousa, Maria Inês. "Improving the manufacturing of mRNA nanomedicines using thermoreversible aqueous biphasic systems and ionic liquids". Paper presented in 6th EBTM, 2024.
Filipa Domingues. "EXPLORING THE USE OF METHYLCELLULOSE-BASED AQUEOUS BIPHASIC SYSTEMS FOR DOUBLE-STRANDED REMOVAL IN MRNA IN VITRO PRODUCTION PROCESSES". Paper presented in 6th EBTM, 2024.
Sousa, Maria Inês. "Improving the manufacturing of mRNA nanomedicines using thermoreversible aqueous biphasic systems and ionic liquids". Paper presented in MicroBiotec, 2023.
Luís C. V. Silva. "The use of thermoreversible ionic liquid-based aqueous biphasic systems as an integrated production-clarification platform in mRNA vaccines manufacturing". Paper presented in Jornadas CICECO 2023, 2023.
Sousa, Maria Inês. "Manufacturing of mRNA nanomedicines using thermoreversible aqueous biphasic systems and ionic liquids". Paper presented in 5th EBTM, 2022.
Sousa, Maria Inês. "Development of integrated strategies for the manufacturing of mRNA resorting to aqueous biphasic systems and ionic liquids". Paper presented in Jornadas CICECO 2022, 2022.
Sousa, Maria Inês. "Integrated manufacturing of mRNA nanomedicines using thermoreversible aqueous biphasic systems and ionic liquids". Paper presented in BPP 2022, 2022.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2025/09/24	Improving the manufacturing of mRNA vaccines with thermoreversible aqueous biphasic systems and ionic liquids	Summer School on Pharmaceutical Analysis (SSPA2025) Division of Medicinal Chemistry, Italian Chemical Society (Italy)
2025/09/24	Sistemas aquosos bifásicos termoreversíveis para a integração da produção/clarificação ¿ de ARNm¿	Workshop "Tecnologias Inovadoras no Fabrico de Vacinas de ARN mensageiro" University of Aveiro (Portugal)
2025/07/18	Improving the manufacturing of mRNA with thermoreversible aqueous biphasic systems and ionic liquids	Research Summit 2025 University of Aveiro
2024/12/06	Production and clarification of mRNA vaccines using integrated processes based on thermoreversible aqueous biphasic systems and ionic liquids¿	Pathlestra CICECO (Portugal)
2024/07	Using thermoreversible aqueous biphasic systems and ionic liquids to improve the manufacturing of mRNA vaccines	Research Summit 2024 Universidade de Aveiro
2024/05	Improving the manufacturing of mRNA vaccines using thermoreversible aqueous biphasic systems and ionic liquids	VI IBIMED Symposium (Portugal)
2023/07	Using thermoreversible aqueous biphasic systems and ionic liquids to improve the manufacturing of mRNA nanomedicines	Research Summit 2023 Universidade de Aveiro (Portugal)
2021	Live-cell imaging, localization and tracking of single mRNA molecules in E. coli cells	Single-molecule bacteriology online symposium Biochemical society
2021	Live-cell imaging, localization and tracking of single mRNA molecules in E. coli cells	SPAOM2021 REMOA and PPBI

Event participation

	Activity description Type of event	Event name Institution / Organization
2018 - Current	Picth presentation Workshop	Scale-up Build Your Own Future Universidade de Aveiro, Portugal

Distinctions

Award

2021	Best Flash Presentation Biochemical Society, United Kingdom
2018	Best picth presentation Universidade de Aveiro, Portugal

Other distinction

2018	Merit distinction Universidade de Aveiro, Portugal