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I finished Pharmaceutical Sciences (MSc) in December of 2016 at Universidade do Algarve, Faculdade de Ciências e Tecnologia. After a 6-month period abroad, in Lyon, I returned to Portugal. In 2018, I started developing his PhD project at Universidade do Algarve - Campus de Gambelas finishing in 2023 in the area of pharmaceutical technology allied with biomedical sciences. The works performed were related to the production, characterisation and therapeutic evaluation of polysaccharide-based micro and nanoparticles envisaged for lung drug delivery. Moreover, my PhD project focused also on the methodological and analytical development of an insufflation device for in vitro tests. At present, I work as an Analytical Scientist at Hovione Farmaciência, S.A..
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Identification

Personal identification

Full name
Jorge Filipe Rodrigues Pontes

Citation names

  • Pontes, Jorge F.

Author identifiers

Ciência ID
CB16-5CBD-8B89
ORCID iD
0000-0002-6447-0242
Google Scholar ID
btBP5fUAAAAJ&hl
Scopus Author Id
57195033461

Email addresses

  • jfpontes@ualg.pt (Professional)

Knowledge fields

  • Medical and Health Sciences - Health Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
French Elementary (A2) Elementary (A2) Elementary (A2) Elementary (A2)
German Elementary (A2) Elementary (A2) Elementary (A2) Beginner (A1)
Education
Degree Classification
2018/03/12 - 2023/06/28
Concluded
 Mecanismos de Doença e Medicina Regenerativa (Doutoramento)
Universidade do Algarve, Portugal
"Dry powders: Developing tools to study the impact of inhalation over respiratory epithelium" (THESIS/DISSERTATION)
2010/09 - 2016/12
Concluded
 Ciências Farmacêuticas (Mestrado)
Major in Sem especialização
Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
"Chitosan/dextran sulfate nanoparticles: stability evaluation and assessment of the effect of different acidic media on nanoparticle preparation " (THESIS/DISSERTATION)
 16 valores
Affiliation

Science

Category
Host institution 		Employer
2017/10 - 2018/03 Research Trainee (Research) Université Claude Bernard Lyon 1, France
Université Claude Bernard Lyon 1, France
2017/01 - 2017/10 Research Trainee (Research) Universidade do Algarve, Portugal
Projects

Other

Designation Funders
2019 - 2021 NANOSPEED - Nanoencapsulation of drugs using biopolymers with specific abilities for drug delivery
5116/
PhD Student Fellow
Centro de Ciências do Mar, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2015 - 2015 Fighting TB: Development of microparticulate systems to target alveolar macrophages in tuberculosis therapy
info:eu-repo/grantAgreement/FCT/3599-PPCDT/124096/PT
Master Student Fellow
Universidade do Algarve, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Pontes, Jorge F.; Fonseca, Magda; Macedo, Ana; Grenha, Ana; Fonte, Pedro. "New and Revisited Approaches on the Transdermal Delivery of Polyphenols-Loaded Nanoparticles for Melanoma Prevention and Treatment". In Phytopharmaceuticals and Herbal Drugs: Prospects and Safety Issues in the Delivery of Natural Products. Elsevier, 2023.
    Accepted
  2. Moreira, Juliana Botelho; de Morais, Etiele Greque; de Almeida, Ana Claudia Araujo; Pontes, Jorge F.; Grenha, Ana; Barreira, Luísa; Varela, João; Costa, Jorge Alberto Vieira; de Morais, Michele Greque. "Microalgal Applications in Nanotechnology: An Outstanding Tool for Nanocompounds Synthesis and Bioproducts Obtention". In Bioprospecting Algae for Nanosized Materials, 95-116. Springer International Publishing, 2021.
    Published • 10.1007/978-3-030-81557-8_4
  3. Bebianno, Maria João; Rocha, Thiago Lopes; Pontes, Jorge Filipe; Amaral, André Corrêa; Grenha, Ana. "Potential Ecotoxicological Risk of Nanopharmaceuticals in the Aquatic Environment". In Nanopharmaceuticals: Principles and Applications Vol. 2, 289-317. Springer International Publishing, 2020.
    Published • 10.1007/978-3-030-44921-6_8
Conference poster
  1. Grenha, Ana; Guerreiro, Filipa; Pontes, Jorge F.; Cruz, Joana; Rico, João; Gaspar, Maria Manuela; Rosa da Costa, Ana M. "Inhalable therapy of tuberculosis: Matching the delivery route with the infection route". Paper presented in 36º Congresso de Pneumologia, 2020.
  2. Pontes, Jorge F.; Braz, Luis; Costa, Ana Rosa da; Almouazen, Eyad; Lollo, Giovanna; Grenha, Ana. "Stability evaluation of sulphated locust bean gum-coated lipid nanocapsules". Paper presented in XIIIth Spanish-Portuguese Conference on Controlled Drug Delivery, 2020.
  3. Flórez-Fernández, Noelia; Pontes, Jorge F.; Domínguez, Herminia; Grenha, Ana. "Evaluation of nanosystems based on biopolymers: Fucoidan from the edible brown seaweed Laminaria japonica and Chitosan". Paper presented in XIIIth Spanish-Portuguese Conference on Controlled Drug Delivery, 2020.
  4. Flórez-Fernández, Noelia; Afonso, Inês; Pontes, Jorge F.; Domínguez, Herminia; Grenha, Ana. "Development of polysaccharide-based nanosystem using marine-based polymers". Paper presented in XXV Encontro Galego-Portugues de Química, 2019.
  5. Pontes, Jorge F.; Braz, Luis; Costa, Ana Rosa da; Almouazen, Eyad; Lollo, Giovanna; Grenha, Ana. "Development of nanocapsules using a locust bean gum sulfate derivative". Paper presented in 22nd International Symposium on Microencapsultation, 2019.
  6. Araújo, Nuna; Viegas, Carla; Pontes, Jorge F.; Marreiros, Catarina; Raimundo, Pedro; Macedo, Anjos; Alves de Matos, António; et al. "Nanoencapsulation as a novel delivery approach for therapeutic applications of gla-rich protein (GRP)". Paper presented in 4th International Congress of CiiEM - Health, Well-Being and Ageing in the XXI Century, 2019.
  7. Gaspar, Maria Manuela; Rodrigues, Susana; Cunha, Ludmylla; Musacchio, Flávia; Pontes, Jorge F.; Guerreiro, Filipa; Grenha, Ana. "Gum-based microparticles: An inhalable platform for the treatment of lung tuberculosis". Paper presented in CRS Annual Meeting and Exposition, 2018.
  8. Pontes, Jorge F.; Cordeiro, Clara; Grenha, Ana. "Design of experiments to study the stability of chitosan/dextran sulfate (CS/DS) nanoparticles". Paper presented in CRS Annual Meeting and Exposition, 2018.
  9. Pontes, Jorge F.; Cordeiro, Clara; Grenha, Ana. "Chitosan/dextran sulfate (CS/DS) nanoparticles: Stability evaluation using factorial design". Paper presented in 21st International Symposium on Microencapsulation, 2017.
  10. Araújo, Nuna; Viegas, Carla; Pontes, Jorge F.; Magalhães, J.; Blanco, F. J.; Macedo, Anjos; Grenha, Ana; Simes, Dina Costa. "Nano-encapsulation of gla-rich protein (GRP) and potential added value as a therapeutic agent for osteoarthritis". Paper presented in 21st International Symposium on Microencapsulation, 2017.
Journal article
  1. Pontes, Jorge F.; Diogo, Hermínio P.; Conceição, Eusébio; Almeida, Maria P.; Borges dos Santos, Rui M.; Grenha, Ana. "Development of a dry powder insufflation device with application in in vitro cell-based assays in the context of respiratory delivery". European Journal of Pharmaceutical Sciences 197 (2024): 106775. https://doi.org/10.1016/j.ejps.2024.106775.
    Published • 10.1016/j.ejps.2024.106775
  2. Guerreiro, Filipa; Pontes, Jorge F.; Gaspar, Maria Manuela; Rosa da Costa, Ana M.; Faleiro, Maria Leonor; Grenha, Ana. "Respirable konjac glucomannan microparticles as antitubercular drug carriers: Effects of in vitro and in vivo interactions". International Journal of Biological Macromolecules 248 (2023): 125838. http://dx.doi.org/10.1016/j.ijbiomac.2023.125838.
    10.1016/j.ijbiomac.2023.125838
  3. Nuc, Zofia; Brusotti, Gloria; Catenacci, Laura; Grenha, Ana; Pontes, Jorge F.; Pinto da Silva, Joana; Rosa da Costa, Ana Maria; et al. "Pontastacus leptodactylus (Eschscholtz, 1823) and Faxonius limosus (Rafinesque, 1817) as New, Alternative Sources of Chitin and Chitosan". Water 15 17 (2023): 3024. http://dx.doi.org/10.3390/w15173024.
    Published • 10.3390/w15173024
  4. Flórez-Fernández, Noelia; Pontes, Jorge F.; Guerreiro, Filipa; Afonso, Inês T.; Lollo, Giovanna; Torres, Maria Dolores; Domínguez, Herminia; Costa, Ana M. Rosa da; Grenha, Ana. "Fucoidan from Fucus vesiculosus: Evaluation of the Impact of the Sulphate Content on Nanoparticle Production and Cell Toxicity". Marine Drugs 21 2 (2023): 115. http://dx.doi.org/10.3390/md21020115.
    10.3390/md21020115
  5. Viegas, Carla S. B.; Araújo, Nuna; Carreira, Joana; Pontes, Jorge F.; Macedo, Anjos L.; Vinhas, Maurícia; Moreira, Ana S.; et al. "Nanoencapsulation of Gla-Rich Protein (GRP) as a Novel Approach to Target Inflammation". International Journal of Molecular Sciences 23 9 (2022): 4813. http://dx.doi.org/10.3390/ijms23094813.
    Published • 10.3390/ijms23094813
  6. Pontes, Jorge F.; Diogo, Hermínio P.; Conceição, Eusebio; Musacchio, Flávia; Borges dos Santos, Rui M.; Grenha, Ana. "Development of a prototype of an aerosolization device for dry powders to improve in vitro cell-based assays in the context of lung delivery". Journal of Aerosol Medicine and Pulmonary Drug Delivery 35 2 (2022): A20-A20. Drug Delivery to the Lungs 2021: https://www.liebertpub.com/doi/abs/10.1089/jamp.2022.ab01.abstracts.
    Published
  7. Pontes, Jorge F.; Duarte, Emanuel; Flórez-Fernández, Noelia; Rico, João; Cruz, Joana; Lollo, Giovanna; Grenha, Ana. "Fucoidan-coated lipid nanocapsules encapsulating a model drug for lung drug delivery". Journal of Aerosol Medicine and Pulmonary Drug Delivery 34 3 (2021): A19. Drug Delivery to the Lungs 2020: https://www.liebertpub.com/doi/full/10.1089/jamp.2021.ab01.abstracts.
    Published
  8. Araújo, Nuna; Viegas, Carla; Pontes, Jorge F.; Marreiros, Catarina; Raimundo, Pedro; Macedo, Anjos L.; Alves de Matos, António; et al. "Nanoencapsulation as a novel delivery approach for therapeutic applications of gla-rich protein (GRP)". Annals of Medicine 53 sup1 (2021): S23-S24. http://dx.doi.org/10.1080/07853890.2021.1896900.
    Published • 10.1080/07853890.2021.1896900
  9. Rosso, Annalisa; Almouazen, Eyad; Pontes, Jorge F.; Andretto, Valentina; Leroux, Marine; Romasko, Etienne; Azzouz-Maache, Samira; et al. "Supersaturable self-microemulsifying delivery systems: An approach to enhance oral bioavailability of benzimidazole anticancer drugs". Drug Delivery and Translational Research (2021):
    Published
  10. Pontes, Jorge F.; Braz, Luis; Rosa da Costa, Ana M; Almouazen, Eyad; Lollo, Giovanna; Grenha, Ana. "Sulphated locust bean gum-coated lipid nanocapsules as potential drug delivery carriers". Journal of Aerosol Medicine and Pulmonary Drug Delivery 33 2 (2020): A15. Drug Delivery to the Lungs 2019: https://www.liebertpub.com/doi/10.1089/jamp.2020.ab01.abstracts.
    Published
  11. Pontes, Jorge F.; Grenha, Ana. "Multifunctional Nanocarriers for Lung Drug Delivery". Nanomaterials 10 2 (2020): 183. http://dx.doi.org/10.3390/nano10020183.
    Published • 10.3390/nano10020183
  12. Guerreiro, Filipa; Pontes, Jorge F.; Costa, Ana Rosa da; Grenha, Ana. "Spray-drying of konjac glucomannan to produce microparticles for an application as antitubercular drug carriers". Powder Technology 342 (2019): 246-252. http://dx.doi.org/10.1016/j.powtec.2018.09.068.
    Published • 10.1016/j.powtec.2018.09.068
  13. Rodrigues, Susana; Alves, Ana D.; Cavaco, Joana S.; Pontes, Jorge F.; Guerreiro, Filipa; Costa, Ana Rosa da; Buttini, Francesca; Grenha, Ana. "Dual antibiotherapy of tuberculosis mediated by inhalable locust bean gum microparticles". International Journal of Pharmaceutics 529 1-2 (2017): 433-441. http://dx.doi.org/10.1016/j.ijpharm.2017.06.088.
    Published • 10.1016/j.ijpharm.2017.06.088
Magazine article
  1. Pontes, Jorge F.; Flórez-Fernández, Noelia; Afonso, Carolina; Cruz, Joana; Alsayyed, Rahaf; Grenha, Ana. "Será o mar a próxima grande fonte de biomateriais?", UAlgoritmo, 2021, Revista de promoção da ciência/investigação feita na Universidade do Algarve: https://www.researchgate.net/publication/356361104_Volume_3_Numero_2_-Novembro_2021.
Thesis / Dissertation
  1. Pontes, Jorge Filipe Rodrigues. "Chitosan/dextran sulfate nanoparticles: Stability evaluation and assessment of the effect of different acidic media on nanoparticle preparation". Master, Universidade do Algarve Faculdade de Ciências e Tecnologia, 2016. http://hdl.handle.net/10400.1/9913.

Intellectual property

Provisional application for patent
  1. 2022. "Inhalable microparticles of bacterial lysate for prevention of respiratory infections".
    Protected
  2. 2022. "Prototype of a dry powder aerosolisation device for in vitro assays".
    Protected
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2021/12 Development of a prototype of an aerosolization device for dry powders to improve in vitro cell-based assays in the context of lung delivery Drug Delivery to the Lungs
The Aerosol Society (Edinburgh, United Kingdom)
2020/12 Fucoidan-coated lipid nanocapsules encapsulating a model drug for lung drug delivery Drug Delivery to the Lungs
The Aerosol Society (Edinburgh, United Kingdom)
2020/11 Inhalable therapy of tuberculosis: Matching the delivery route with the infection route 36º Congresso de Pneumologia
Sociedade Portuguesa de Pneumologia (Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2017 - 2017 21st International Symposium on Microencapsulation - Member of the organising committee (2017/09/27 - 2017/09/29)
Conference (Member of the Organising Committee)
 Universidade do Algarve, Portugal
2017 - 2017 Open Day at Universidade do Algarve - Responsible for the activities related to Pharmaceutical Technology (2017/02/23 - 2017/02/23)
Exhibition (Member of the Organising Committee)
 Universidade do Algarve, Portugal
Distinctions

Award

2021 Honourable Mention in "Ideias em Caixa, 7th Edition"
Universidade do Algarve, Portugal
2020 Best Oral Communication Award at "36º Congresso de Pneumologia"
Sociedade Portuguesa de Pneumologia, Portugal