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João Fernando Pereira Mendes completed the Doctoral Program in Health Sciences in 2022/07/19 by the Faculty of Medicine of Coimbra University. He concluded his Master´s degree in Biochemistry in 2008 at the University of Beira Interior and his degree in Biochemistry in 2006/09/01 at the University of Beira Interior. João Fernando Pereira Mendes is an Invited Assistant at the Faculty of Medicine of Coimbra University since 2020. He teaches the practical course unit of Genetics in the first year of the integrated Master's degree in Dental Medicine. He teaches the practical course unit on Genetics in the course of Medicinal Chemistry. He collaborates in the teaching of the discipline Biological Basis of Behavior in the course of Psychology. During this time, he has been invited to lecture in the Doctoral Program in Health Sciences. At the moment he is a scientific supervisor for pupils elaborating their final master thesis. He has published seven articles in peer-reviewed journals. Two in quartile one, for in quartile two, and one in quartile three. João Fernando Pereira Mendes also works as a research scientist in the UC Genomics - Institute of Medical Genetics from the Faculty of Medicine at the University of Coimbra. Here he collaborated on several projects including "In2Genome", funded by Horizon 2020 Framework Program; or "Projeto de Capacitação da Região Centro para a Medicina Personalizada/de Precisão, de base genómica", CENTRO-08-5864-FSE-000039, funded by Programa Operacional Regional do Centro. In this field, he had the opportunity to work in diverse research areas namely in accelerating the diagnosis of genetic diseases, including whole-exome analysis; he worked with liquid biopsies and NGS panels, as well as, metagenomic analysis. In addition, he has been involved in giving formation to undergraduate students in laboratory practices. While he was in this institution he was under the evaluation of SIADAP receiving the appraisal of adequate performance.
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Identification

Personal identification

Full name
João Fernando Pereira Mendes

Citation names

  • Mendes, João

Author identifiers

Ciência ID
C614-3186-20BC

Websites

Knowledge fields

  • Medical and Health Sciences - Health Sciences
  • Natural sciences - Biological Sciences - Biochemistry
  • Medical and Health Sciences - Basic Medicine - Human Genetics
  • Medical and Health Sciences - Basic Medicine - Immunology
  • Natural sciences - Biological Sciences - Genetics and Heredity
Education
Degree Classification
2017/10/01 - 2022/07/19
Concluded
 Doctoral Programme in Health Sciences (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
"Innate Lymphoid Cells at the Maternal-Fetal Interface. The role of Progesterone in Preterm Birth." (THESIS/DISSERTATION)
 Approved with praise and distinction (17.4)
2008
Concluded
 Bioquímica (Mestrado)
Universidade da Beira Interior, Portugal
"Farmacogenética na Transplantação de Orgãos Sólidos" (THESIS/DISSERTATION)
 16
1999/10 - 2006/09/01
Concluded
 Bioquímica (Licenciatura)
Universidade da Beira Interior, Portugal
"The Expression Patterns of Anti-Mulerian Hormone in Zebrafish Testis" (THESIS/DISSERTATION)
 13
Affiliation

Science

Category
Host institution 		Employer
2017/09/01 - Current Researcher (Research) Faculdade de Medicina da Universidade de Coimbra, Portugal
Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, Portugal
2016/09/01 - Current Researcher (Research) Universidade de Coimbra Faculdade de Medicina, Portugal
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia - CIMAGO, Portugal
2016/05/01 - 2019/04/30 Researcher (Research) Universidade de Coimbra Faculdade de Medicina, Portugal
Instituto de Patologia Geral, Portugal
2011/04/01 - 2012/08/06 Researcher (Research) Instituto Português do Sangue e da Transplantação IP, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2020/09/30 - Current Invited Assistant (University Teacher) Universidade de Coimbra Faculdade de Medicina, Portugal
Faculty of Medicine of Coimbra University, Portugal

Other Careers

Category
Host institution 		Employer
2019/05/01 - Current Técnico Superior (Técnico Superior) Universidade de Coimbra Faculdade de Medicina, Portugal
UC Genomics - Medical Genetics Institute, Portugal

Others

Category
Host institution 		Employer
2012/08/06 - 2013/08/06 Technical Support Diagnostica LongWood, Spain
2008/02/01 - 2011/01/31 Laboratory Technician Associação Portuguesa Contra a Leucemia , Portugal
Instituto Português do Sangue e da Transplantação IP, Portugal
Projects

Grant

Designation Funders
2017/09 - 2018/09 Progesterone in Pretirm Birth: Role of Regulatory T cells
06/14
Researcher
Centro de Investigação em Meio Ambiente, Genética e Oncobiologia - CIMAGO
2011/04/01 - 2012/08/06 Functional and phenotipical characterization of mesenchymal stem cells from umbilical cord blood
0
Integration into Research Grant Fellow
Instituto Português do Sangue e da Transplantação IP, Portugal
Concluded
Outputs

Publications

Conference poster
  1. I. Gante; J. Martins Ribeiro; A. Gomes; Mendes, João; V. Almeida; F.S. Regateiro; F. Caramelo; H. Coimbra Silva; M. Figueiredo Dias. "Exploring the lymph node’s microenvironment for personalized management of luminal A breast cancer". 2022.
    10.1016/s0959-8049(22)01569-6
  2. Mendes, João. "Innate Lymphoid Cells at the maternal fetus interface: Implications in Preterm Birth?". Paper presented in CIMAGO Scientific Meeting, 2018.
Journal article
  1. Andre Lazaro; Igor Tiago; Joao Mendes; Joana Ribeiro; Antonio Bernardes; Fernando Oliveira; Fernando Regateiro; Francisco Caramelo; Henriqueta Silva. "Sleeve Gastrectomy and Gastric Bypass Impact in Patient’s Metabolic, Gut Microbiome, and Immuno-inflammatory Profiles—A Comparative Study". Obesity Surgery (2025): http://dx.doi.org/10.1007/s11695-025-07708-9.
    10.1007/s11695-025-07708-9
  2. João Mendes; João Palma; Amândio Santos; Joana Ribeiro; Bárbara Oliveiros; Henriqueta Silva. "Association of rs35767 polymorphism in the IGF1 gene with athletic performance in power and endurance sports: A meta-analysis". Growth Hormone & IGF Research (2024): http://dx.doi.org/10.1016/j.ghir.2024.101627.
    10.1016/j.ghir.2024.101627
  3. Joana Martins Ribeiro; João Mendes; Inês Gante; Margarida Figueiredo-Dias; Vânia Almeida; Ana Gomes; Fernando Jesus Regateiro; et al. "Two Different Immune Profiles Are Identified in Sentinel Lymph Nodes of Early-Stage Breast Cancer". Cancers (2024): https://doi.org/10.3390/cancers16162881.
    10.3390/cancers16162881
  4. João Mendes; Adriana Rocha Guimarães; Joana Martins Ribeiro; Bárbara Oliveiros; Luís Alcides Mesquita; Maria Helena Fernandes; Francisco José Fernandes do Vale; Henriqueta Coimbra Silva. "Role of MTHFR, IRF6, PAX7 and TP63 SNPs in susceptibility to non-syndromic orofacial cleft, a candidate gene study in a Portuguese population". Orthodontics & Craniofacial Research (2024): https://doi.org/10.1111/ocr.12838.
    10.1111/ocr.12838
  5. Inês Gante; Joana Martins Ribeiro; João Mendes; Ana Gomes; Vânia Almeida; Frederico Soares Regateiro; Francisco Caramelo; Henriqueta Coimbra Silva; Margarida Figueiredo-Dias. "One Step Nucleic Acid Amplification (OSNA) Lysate Samples Are Suitable to Establish a Transcriptional Metastatic Signature in Patients with Early Stage Hormone Receptors-Positive Breast Cancer". Cancers (2022): https://doi.org/10.3390/cancers14235855.
    10.3390/cancers14235855
  6. Maria João Cavaco; Celeste Alcobia; Bárbara Oliveiros; Luís Alcides Mesquita; Aurora Carvalho; Fernando Matos; José Miguel Carvalho; et al. "Clinical and Genetic Risk Factors for Drug-Induced Liver Injury Associated with Anti-Tuberculosis Treatment—A Study from Patients of Portuguese Health Centers". Journal of Personalized Medicine (2022): https://doi.org/10.3390/jpm12050790.
    10.3390/jpm12050790
  7. Sérgio B. Sousa; Maria José Simões; Belinda Campos-Xavier; Hugo Froufe; Carolina Ribeiro; Mendes, João; Joaquim Sá; et al. "Abstracts from the 54th European Society of Human Genetics (ESHG) Conference: e-Posters". European Journal of Human Genetics 30 S1 (2022): 88-608. http://dx.doi.org/10.1038/s41431-021-01026-1.
    10.1038/s41431-021-01026-1
  8. João Mendes; Paulo Rodrigues-Santos; Ana Luísa Areia; Jani-Sofia Almeida; Vera Alves; Manuel Santos-Rosa; Anabela Mota-Pinto. "Type 2 and type 3 innate lymphoid cells at the maternal-fetal interface: implications in preterm birth". BMC Immunology (2021): https://doi.org/10.1186/s12865-021-00423-x.
    10.1186/s12865-021-00423-x
  9. Mendes, João. "Innate Lymphoid Cells in Human Pregnancy". Frontiers in Immunology 11 (2020): http://dx.doi.org/10.3389/fimmu.2020.551707.
    10.3389/fimmu.2020.551707
  10. Alves, José Luís; Mendes, João; Leitão, Ricardo; Silva, Ana Paula; Pinto, Anabela Mota; Alves, J.L.; Mendes, J.; et al. "A multi-staged neuropeptide response to traumatic brain injury". European Journal of Trauma and Emergency Surgery 48 1 (2020): 507-517. http://dx.doi.org/10.1007/s00068-020-01431-z.
  11. Martinho A; Mendes J; Simões O; Nunes R; Gomes J; Dias Castro E; Leiria-Pinto P; et al. "Mutations analysis of C1 inhibitor coding sequence gene among Portuguese patients with hereditary angioedema.". (2013): http://europepmc.org/abstract/med/23123409.
    10.1016/j.molimm.2012.09.003
  12. Mendes, João. "ABSTRACTS - 24th European Immunogenetics and Histocompatibility Conference 17th Annual Meeting of the Italian Society for Immunogenetics and Transplantation Biology, May 15-18, 2010, Florence, Italy". Tissue Antigens 75 5 (2010): 466-643. http://dx.doi.org/10.1111/j.1399-0039.2010.01488.x.
    10.1111/j.1399-0039.2010.01488.x
  13. Mendes, João. "Abstracts for the 23rd European Immunogenetics and Histocompatibility Conference, Ulm, Germany, 9-12 May 2009". Tissue Antigens 73 5 (2009): 385-523. http://dx.doi.org/10.1111/j.1399-0039.2009.01255.x.
    10.1111/j.1399-0039.2009.01255.x
  14. Mendes J; Martinho A; Simoes O; Mota A; Breitenfeld L; Pais L. "Genetic polymorphisms in CYP3A5 and MDR1 genes and their correlations with plasma levels of tacrolimus and cyclosporine in renal transplant recipients.". (2009): http://europepmc.org/abstract/med/19376366.
    10.1016/j.transproceed.2009.01.050

Other

Other output
  1. Exploring the lymph node’s microenvironment for personalized management of Luminal A breast cancer. 2022. Gante, I.; Ribeiro, J.M.; Mendes, J.; Gomes, A.; Almeida, V.; Regateiro, F.S.; Caramelo, F.; Silva, H.C.; Dias, M.F.. http://www.scopus.com/inward/record.url?eid=2-s2.0-85142122824&partnerID=MN8TOARS.
    10.21203/rs.3.rs-2136378
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2010/03/26 Molecular and celular studies in transplantation. Curso de Hematologia e Imunologia Clínico-laboratorial
Instituto Politécnico de Bragança (Bragança, Portugal)
2009/06/24 Pharmacogenetics in Transplantation One Lambda's 10th European Clinical Histicompatibility Workshop
One Lambda's (Evian, France)
2008/11/21 Pharmacogenetics in Transplantation II Congresso das Ciências Aplicadas na Saúde
Escola Superior de Tecnologia da Saúde de Coimbra (Coimbra, Portugal)
2008/10/03 Genetic Polymorphisms in CYP3A5 and MDR1 Genes and Their Correlations With Plasma Levels of Tacrolimus and Cyclosporine in Renal Transplant Recipients VII Congresso Luso-Brasileiro de Transplantação
Sociedade Portuguesa de Transplantação (Albufeira, Portugal)

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2017 - 2017 Participation Modular Structure Training In Laboratoy Aanimal Science, held at Coimbra University (Function A, Function B and Function C) a FELASA certified course. October 2017
Other
 Modular Structure Training In Laboratoy Aanimal Science
Universidade de Coimbra Faculdade de Medicina, Portugal

Consulting

Activity description Institution / Organization
2020/04/01 - 2020/06/30 Services provided at the Clinical Analysis Laboratory of the University of Coimbra (UC), a high-security unit dedicated to the performance of Covid-19 diagnostic tests. Universidade de Coimbra Faculdade de Medicina, Portugal