???global.info.a_carregar???
Marta Paiva. Concluiu o(a) Doutoramento em Cellular Biology PhD em 2011/10/21 pelo(a) Universidade de Coimbra Faculdade de Ciencias e Tecnologia e Licenciatura em Biochemistry em 2005/07/01 pelo(a) Universidade de Coimbra Faculdade de Ciencias e Tecnologia. É Investigador Contratado no(a) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica. Publicou 17 artigos em revistas especializadas. Recebeu 1 prémio(s) e/ou homenagens.
Identification

Personal identification

Full name
Marta Paiva

Citation names

  • Paiva, Marta
  • Paiva, Marta Abreu

Author identifiers

Ciência ID
C611-E097-77C7
ORCID iD
0000-0003-2933-9895

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Italian Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2011/10/21
Concluded
 Cellular Biology PhD (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Impact of diabetes and its pharmacological treatment on cardiovascular function: studies on ischaemia-reperfusion models" (THESIS/DISSERTATION)
 Approved with honours and distinction
2005/07/01
Concluded
 Biochemistry (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Insulin’s impact on global ischemia-reperfusion ex- vivo models" (THESIS/DISSERTATION)
 17 valores
Affiliation

Science

Category
Host institution 		Employer
2018/08/01 - Current Contracted Researcher (Research) Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2017/10/01 - 2018/07/31 Postdoc (Research) iNOVA4Health, Portugal
iNOVA4Health, Portugal
2014/02/01 - 2017/09/01 Postdoc (Research) Imperial College London Department of Medicine, United Kingdom
Imperial College London Faculty of Medicine, United Kingdom
2011/01/01 - 2014/01/31 Research Assistant (Research) Imperial College Faculty of Medicine - Hammersmith Campus, United Kingdom
Imperial College Faculty of Medicine - Hammersmith Campus, United Kingdom
2010/01/01 - 2010/10/30 Research Assistant (Research) University College London Hatter Cardiovascular Institute, United Kingdom
University College London Hatter Cardiovascular Institute, United Kingdom
2004/09/01 - 2005/07/31 Research Trainee (Research) Centro Hospitalar e Universitário de Coimbra EPE, Portugal
Hospitais da Universidade de Coimbra, Portugal
Projects

Grant

Designation Funders
2018/04 - 2021/09 MetaCardio: Metabolic signatures of human pluripotent stem cells derived cardiomyocytes for improved cell therapy
02/SAITC/2017/032566
 Fundação para a Ciência e a Tecnologia
2014/12 - 2017/11 CARDIOSTEM- Engineered cardiac tissues and stem cell-based therapies for cardiovascular applications
grant.Provided by PTCRIS: 137185
 Stichting Weten
2010/04 - 2013/06 Heart regeneration by embryonic vascular cells and a biomimetic scaffold
grant.Provided by PTCRIS: 98468
 Stichting Weten
Outputs

Publications

Journal article
  1. Fiedler LR; Chapman K; Xie M; Maifoshie E; Jenkins M; Golforoush PA; Bellahcene M; et al. "MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo.". Cell stem cell (2019): http://europepmc.org/abstract/med/30853557.
    10.1016/j.stem.2019.01.013
  2. Adamowicz, Martyna; Morgan, Claire C.; Haubner, Bernhard J.; Noseda, Michela; Collins, Melissa J.; Paiva, Marta Abreu; Srivastava, Prashant K.; et al. "Functionally Conserved Noncoding Regulators of Cardiomyocyte Proliferation and Regeneration in Mouse and Human". Circulation-Cardiovascular Genetics 11 2 (2018): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000426177700003&KeyUID=WOS:000426177700003.
    10.1161/CIRCGEN.117.001805
  3. Paiva, Marta. "Multimodal Hydrogel-Based Platform To Deliver and Monitor Cardiac Progenitor/Stem Cell Engraftment.". ACS central science (2017): http://europepmc.org/abstract/med/28470052.
    10.1021/acscentsci.7b00039
  4. Paiva, Marta. "Enhanced efficiency of genetic programming toward cardiomyocyte creation through topographical cues.". Biomaterials (2015): http://europepmc.org/abstract/med/26302234.
    10.1016/j.biomaterials.2015.07.063
  5. Paiva, Marta. "PDGFRa demarcates the cardiogenic clonogenic Sca1+ stem/progenitor cell in adult murine myocardium.". Nature communications (2015): http://europepmc.org/abstract/med/25980517.
    10.1038/ncomms7930
  6. Paiva, Marta. "Forward Programming of Cardiac Stem Cells by Homogeneous Transduction with MYOCD plus TBX5.". PloS one (2015): http://europepmc.org/abstract/med/26047103.
    10.1371/journal.pone.0125384
  7. Noseda, M.; Abreu-Paiva, M.; Schneider, M.D.; Michela Noseda; Marta Abreu-Paiva; Michael D. Schneider. "The quest for the adult cardiac stem cell". Circulation Journal 79 7 (2015): 1422-1430. http://www.scopus.com/inward/record.url?eid=2-s2.0-84934268195&partnerID=MN8TOARS.
    10.1253/circj.CJ-15-0557
  8. Noseda, M.; Harada, M.; Mcsweeney, S.; Leja, T.; Belian, E.; Macaulay, I.; Paiva, M. Abreu; et al. "PDGFRalpha demarcates the cardiogenic and clonogenic Sca-1+stem cell". Cardiovascular Research 103 (2014): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000343730100460&KeyUID=WOS:000343730100460.
    10.1093/cvr/cvu098.25
  9. Belian, Elisa; Noseda, Michela; Leja, Thomas; Harada, Mutsuo; Lumbers, Richard T.; Paiva, Marta S. Abreu; East, Nick; Sampson, Robert; Schneider, Michael D.. "Is Myocardin a limiting factor for cardiac programming?". Circulation Research 111 12 (2012): E386-E386. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000311994700030&KeyUID=WOS:000311994700030.
  10. Noseda, Michela; De Smith, Adam J.; Leia, Thomas; Rao, Pulivarthi H.; Paiva, Marta S. Abreu; Al-Beidh, Farah; Blakemore, Alex I.; Schneider, Michael D.. "The Cdkn2a/2b Tumour Suppressor Locus is a Hot Spot for Genome Instability in Mouse Cardiac Progenitor Cells". Circulation 126 21 (2012): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000208885008239&KeyUID=WOS:000208885008239.
  11. Paiva, Marta. "Enhancing AMPK activation during ischemia protects the diabetic heart against reperfusion injury.". American Journal of Physiology - Heart and Circulatory Physiology (2011): http://europepmc.org/abstract/med/21421816.
    10.1152/ajpheart.00707.2010
  12. Paiva, Marta. "Transitory activation of AMPK at reperfusion protects the ischaemic-reperfused rat myocardium against infarction.". Cardiovascular drugs and therapy (2010): http://europepmc.org/abstract/med/20229055.
    10.1007/s10557-010-6222-3
  13. Paiva, M.; Riksen, N.P.; Davidson, S.M.; Hausenloy, D.J.; Monteiro, P.; Gonçalves, L.; Providência, L.; et al. "Metformin prevents myocardial reperfusion injury by activating the adenosine receptor". Journal of Cardiovascular Pharmacology 53 5 (2009): 373-378. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650921900&partnerID=MN8TOARS.
    10.1097/FJC.0b013e31819fd4e7
  14. Paiva, Marta. "Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening.". Basic research in cardiology (2008): http://europepmc.org/abstract/med/18080084.
    10.1007/s00395-007-0691-y
  15. Monteiro, P. F.; Paiva, M.; Carreira, R.; Duarte, A. I.; Goncalves, L. M.; Providencia, L. A.; Monteiro, Pedro; et al. "Effect of chronic insulin therapy in the mitochondrial function in an ex-vivo animal model of global myocardial ischemia-reperfusion". European Heart Journal 27 5 (2006): 527-527. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000240668403436&KeyUID=WOS:000240668403436.
  16. Paiva, Marta. "Impact of acute ischemia-reperfusion on myocardial mitochondrial function in an ex-vivo model of global myocardial ischemia.". Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology (2005): http://europepmc.org/abstract/med/16463987.
  17. Paiva, M.A.; Carreira, R.; Monteiro, P.; Gonçalves, L.M.; Providência, L.A.. "Impact of acute ischemia-reperfusion on myocardial mitochondrial function in an ex-vivo model of global myocardial ischemia | Impacto da isquemia-reperfusão aguda na função mitocondrial num modelo animal ex-vivo de isquemia global". Revista Portuguesa de Cardiologia 24 11 (2005): 1381-1392. http://www.scopus.com/inward/record.url?eid=2-s2.0-30944444776&partnerID=MN8TOARS.
Distinctions

Award

2019 Runner-up for Best Poster Presentation at the 53rd Annual Scientific Meeting 22th- 24th May 2019 - Coimbra, Portugal
European Society of Clinical Investigation, Netherlands

Other distinction

2005 Alvaro JS Basto FCTUC /CGD award
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal