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Teresa Summavielle has a degree in biochemistry and a PhD in developmental neurotoxicology. Presently she coordinates the Neurobiology and Neurologic Disorders integrative program at i3S, where she is also Vice-Director and Head of the Addiction Biology Group. Her research explores the crosstalk between neurons and glial cells under exposure to psychoactive substances and has a strong focus on neuro-immune regulation. She coordinates courses in Neurobiology of Addiction and Neurotoxicology in doctoral and master programs (University of Porto) and she is an invited professor at the Escola Superior de Saúde (Polytechnic University). She supervised 6 postdocs, 10 PhDs (2 ongoing) and 16 Master students and attracted close to 3M euros of competitive national and international funding, which include a FP7 EU project and recently she integrated the EU LIVESAFER project. Her recent publications include Neuropsychopharmacology, Nat Commun, Cell Rep, Sci Signal, Brain, Brain Commun, Neurosc Biobehav Rev. She is also highly engaged in the scientific and academic community: She on the Board of the Portuguese Neuroscience Society and on the Board of the National Union for Higher Education (contributing for better Science Policy). Advocating for responsible experimentation, she integrates the CARE committee at FENS. On a societal perspective, she runs since 2008 a science-based campaign to prevent drug use by the adolescent population and is an acting city council women at the municipality of Porto. Recognising her societal impact,she was awarded a Women in Science distinction by the National Agency for Scientific and Technological Culture (Ciência Viva).
Identification

Personal identification

Full name
Maria Teresa Burnay Summavielle
Gender
Female

Citation names

  • Summavielle, Teresa

Author identifiers

Ciência ID
C41E-0816-5C85
ORCID iD
0000-0003-2548-6281
Researcher Id
C-9776-2012
Scopus Author Id
6603092949

Email addresses

  • tsummavi@ibmc.up.pt (Professional)

Addresses

  • I3S, Instituto de Investigação e Inovação em Saúde, Addiction Biology Group, R. Alfredo Allen 208, 4200-135, Porto, Porto, Portugal (Professional)

Websites

  • http://www.i3s.up.pt/research-groups/neurobiology-and-neurologic-disorders/addiction-biology (Professional)

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Medical and Health Sciences - Basic Medicine - Toxicology
  • Medical and Health Sciences - Health Sciences - Substance Abuse
Education
Degree Classification
2003/12/10
Concluded
Biomedical Sciences (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Neonatal exposure on the dopaminergic and serotonergic systems of the developing rat" (THESIS/DISSERTATION)
Approved by unanimity
1988/10/01 - 1992/09/30
Concluded
Biochemistry (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
" Role of the Ganglionar Nervous System in Anodonta cygnea" (THESIS/DISSERTATION)
Affiliation

Science

Category
Host institution
Employer
2013/06/01 - Current Principal Investigator (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2008/03/01 - 2013/02/28 Auxiliary Researcher (Research) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2007 - 2008 Postdoc (Research) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2004 - 2007 Postdoc (Research) Universidade do Porto Faculdade de Farmácia, Portugal
1993 - 1997 Research Trainee (Research) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Teaching in Higher Education

Category
Host institution
Employer
2010/09/01 - Current Invited Adjunct Teacher (Polytechnic Teacher) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2016 - 2019 Invited Adjunct Teacher (Polytechnic Teacher) Instituto Politécnico do Porto, Portugal
2013 - 2016 Adjunct Teacher (Polytechnic Teacher) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2002 - 2010 Invited Assistant (Polytechnic Teacher) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal

Positions / Appointments

Category
Host institution
Employer
2023/06/01 - Current Member of the Board Sociedade Portuguesa de Neurociências, Portugal
2023/03/16 - Current Vice-President Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/03 - Current Coordinator of the Neurobiology and Neurologic disorders Research program Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/09 - Current CARE commitee FENS-Kavli Network of Excellence, Belgium
FENS - Federation of European Neuroscience Societies, Belgium
2022/03/01 - Current Vice-president SNESup, Portugal
SNESup, Portugal
2013/09/01 - Current Group Leader at I3S (IBMC) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/06/01 - 2023/05/30 Treasurer Sociedade Portuguesa de Neurociências, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017/10 - 2021/09 Member of the Executive Board Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Others

Category
Host institution
Employer
1998 - 2003 PhD student (Research) Universidade do Porto Faculdade de Medicina, Portugal
Projects

Grant

Designation Funders
2020/03 - 2021/06 Adult-use cannabis regulation: a systematic literature review
OR2019-61834
Invited Scientist Fellow
Universidade Católica Portuguesa Centro de Estudos de Gestão e Economia Aplicada, Portugal
Foundation to Promote Open Society (FPOS) - George Soros Open Society Foundations
Ongoing
2012/03 - 2014/08 The impact of early life adversity on the social behaviour pathways: a crosstalk between oxytocin and corticosteroids Fundação para a Ciência e a Tecnologia
2010/04 - 2013/09 Neuroprotecting mechanisms of carnitine in mitochondrial dysfunction Fundação para a Ciência e a Tecnologia

Contract

Designation Funders
2023/03/01 - 2029/02/28 TREATING - Advanced therapeutic approaches in addiction: targeting the crosstalk between neuronal and glial cells
2022.03699.CEECIND/CP1735/CT0020
Instituto de Astrofísica e Ciências do Espaço, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/01/01 - 2024/12/31 Advanced therapeutic approaches in addiction: targeting neuroinflammation (PI - 249,911.25€ )
PTDC/SAU-TOX/0067/2021
Principal investigator
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/01/01 - 2024/12/31 Profilin1 at the crossroads between microglia, aging and neurodegeneration
PTDC/MED-NEU/1677/2021
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2021 - 2024 LIFESAVER
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Ongoing
2022/01/01 - 2023/06/30 Increasing Vitamin C uptake in Microglia for halting Alzheimer´s disease
EXPL/MED-NEU/0588/2021
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/01/01 - 2023/06/30 STRESS AND BREAST CANCER METASTASIS TO BONE: Exploring the Yin-Yang of sympathetic adrenergic signaling
EXPL/BIA-BQM/0255/2021
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/01 - 2022/04/30 Pathological nerve sprouting in bone metastases: OSTEOCLASTS, what are you doing?
PTDC/MED-PAT/30158/2017
Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/07/26 - 2021/12/31 Individual differences underlying addiction vulnerability: interaction between adolescent environmental enrichment exposure and endogenous oxytocin system (CoPI, 237,518.67€)
PTDC/SAU-TOX/32231/2017
Principal investigator
Instituto de Biologia Molecular e Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2018/10 - 2021/09 Rac1 regulation of microglia homeostasis and pro-inflammatory polarization (CoPi - 224 180,00€)
PTDC/SAU-TOX/31318/2017
Principal investigator
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
FCT - Fundação para a Ciência e Tecnologia
Ongoing
2018/06 - 2021/05 Psychostimulant-induced neuroinflammation: new insight in the crosstalk between microglia, astrocytes and neurons (PI - 237,905.00€)
PTDC/SAU-TOX/30647/2017
Principal investigator
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2018 - 2021 Pathological nerve sprouting in bone metastases: OSTEOCLASTS, what are you doing? (PI at IBMC, 5,000.00€)
PTDC/MED-PAT/30158/2017
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
FCT - Fundação para a Ciência e Tecnologia
Ongoing
2016/06 - 2019/05 Porto Neurosciences and Neurologic Disease Research Initiative at i3S: Research Line (RL) 3 - In-vivo approaches in neuroscience: Development of animal models and research infrastructures (PI - 1,333,513.00€)
NORTE-07-0124-FEDER-0000018
Principal investigator
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Comissao de Coordenacao e Desenvolvimento Regional do Norte
Concluded
2013/06/01 - 2018/05/31 RhoGTPase signaling on long-term methamphetamine-induced neuronal morphological and functional changes in the brain
IF/00875/2012/CP0158/CT0004
Principal investigator
Instituto de Biologia Molecular e Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2013/03 - 2016/09 Neuro-Enhancement: Responsible Research and Innovation (NERRI) (IBMC - 142,299.00€)
FP7-SCIENCE-IN-SOCIETY-2012-1
Researcher
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
European Commission Seventh Framework Programme for Research and Technological Development
Concluded
2013/06 - 2015/12 Neurodegenerative disorders. Sub-Task 1.7 “Can regulation of cytoskeleton actin dynamics prevent methamphetamine-induced dysfunction?”
NORTE-07-0124-FEDER-000001
Principal investigator
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Comissao de Coordenacao e Desenvolvimento Regional do Norte
Concluded
2013/06/01 - 2015/09/30 Methylphenidate and blood-brain barrier changes in health and attention deficit hyperactivity disorder
PTDC/NEU-OSD/0312/2012
Researcher
Universidade de Coimbra, Portugal

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2012/03/01 - 2014/08/31 The impact of early life adversity on the social behaviour pathways: a crosstalk between oxytocin and corticosteroids
PTDC/PSI-PCO/116612/2010
Researcher
Universidade do Minho, Portugal

Universidade do Minho Centro de Investigação em Psicologia, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/04/01 - 2013/09/30 Effects of Ketamine anaesthesia in animal models used on research (PI at IBMC - 80 606 €)
PTDC/CVT/099022/2008
Principal investigator
Centro de Ciência Animal e Veterinária, Portugal

Universidade de Trás-os-Montes e Alto Douro, Portugal

Instituto de Biologia Molecular e Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/04/01 - 2013/09/30 Neuroprotecting mechanisms of carnitine in mitochondrial dysfunction (PI - 175 850 €)
PTDC/SAU-OSM/100630/2008
Principal investigator
Instituto de Biologia Molecular e Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/02/05 - 2013/07/31 NPwhY - Innervation and angiogenesis for the benefit of osteogenesis: the involvement of NPY neuronal pathway in bone repair (PI at IBMC - 5,860.00€)
PTDC/SAU-OSM/101469/2008
Research Fellow
Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Faculdade de Medicina, Portugal

Instituto de Biologia Molecular e Celular, Portugal

Garvan Institute of Medical Research, Australia

Centre Hospitalier Universitaire Vaudois Service de pharmacologie clinique, Switzerland

Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2008/03/01 - 2013/02/28 Neonatal exposure on the dopaminergic and serotonergic system of the developing rat
CONT_DOUT/23/IBMC/316/6098/ 13/2006
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2009/06/01 - 2010/05/30 Neuroprotective Effects of Acetyl-L-Carnitine, Acetyl-L-Carnitine Glycinate, Acetyl-L-Carnitine Taurinate, DHA, Resveratrol and Lipoic Acid alone and combination in an in vitro model of ischemia (PI - 10,000.00 €)
--
Principal investigator
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Stabilimento e Centro di Ricerche Sigma-Tau SpA
Concluded
2009 - 2010 Prevention of Ecstasy abuse in the adolescent - "e-drogas" (PI - 25,000.00€)
--
Principal investigator
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Fundação Calouste Gulbenkian
Concluded
2005/04/01 - 2008/02/29 EFEITOS NEUROTÓXICOS DA EXPOSIÇÃO A MDMA/ECSTASY NO RATO ADOLESCENTE
SFRH/BPD/20997/2004
Post-doc
Fundação para a Ciência e a Tecnologia
Concluded
2004 - 2008 Behavioral and neurochemical effects of MDMA (Ecstasy) throughout adolescence. (PI - 100,000.00¿)
--
Principal investigator
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Fundação Calouste Gulbenkian
Concluded
1998/01/01 - 2002/04/30 SERÃO AS ÁREAS DOPAMINÉRGICAS E SEROTONINÉRGICAS DO SISTEMA NERVOSO CENTRAL DO RATO IGUAL OU DIFERENCIAL- MENTE AFECTADAS PELA EXPOSIÇÃO À COCAÍNA DURANTE O DESENVOLVIMENTO
PRAXIS XXI/BD/14742/97
PhD Student Fellow
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Alves, C.J.; Magalhães, A.; Monteiro, P.R.; Summavielle, T.. "Very Long-Term Effects of Chronic Cocaine on Anxiety and Stress". In The Neuroscience of Cocaine, 343-352. London, United Kingdom: Elsevier, 2017.
    10.1016/b978-0-12-803750-8.00035-x
  2. Lobo, Andrea; Summavielle, Teresa. "Brain Neurochemistry and Cognitive Performance: Neurotransmitter Systems". In Biomedical Chemistry, 148-176. De Gruyter Open, 2015.
    Published • 10.1515/9783110468755-006
  3. Carvalho, Carmo; Veríssimo, Lurdes; Summavielle, Teresa. "Prevenção do Consumo de Álcool e Drogas: Da Centralidade da Informação à Centralidade da Relação". In Estudos sobre o Álcool: Contributo para a Prática, 105-140. Axioma - Publicações da Faculdade de Filosofia, 2015.
    10.17990/axi/2015_9789726972372_105
  4. Summavielle, T; Relvas, J.B.. "Células do sistema nervoso". In Biologia Molecular e Celular, edited by Carlos Azevedo ; Claudio Sunkel, 455-464. Porto, Portugal: Lidel, 2012.
    Published
  5. Summavielle T. "Alguma luz dentro da caixa". In Exuberâncias da caixa Preta, edited by Maria Rui Vilar; Sonia Martins; Julio Borlido Santos, 90-95. Porto, Portugal: Edições ESAD, 2011.
    Published
  6. Summavielle, Teresa. "Drug metabolism". In Assessing illicit drugs in wastewater: Potential and limitations of a new monitoring approach, edited by Frost N; Griffiths P. Luxembourg: Office for Official Publications of the European Communities, 2008.
    Published
Conference abstract
  1. Andrade, Elva Bonifacio; Magalhães, Ana; Puga, Ana; Costa, Madalena; Bravo, Joana; Portugal, Camila Cabral; Ribeiro, Adilia; et al. "AB009. A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection". 2020.
    Published • 10.21037/pm.2020.ab009
  2. Lobo, Andrea; Terceiro, Ana F.; Carvalhais, Lia; Magalhães, Ana; Garcia, Andreia; Bettencourt Relvas, João; Summavielle, Teresa. "Psychostimulant induce neuronal plasticity by cytoskeleton remodeling via cdc42 pathway". Paper presented in I3S Annual Meeting 2019, Porto, 2019.
    Published
  3. Summavielle, Teresa; João Paulo Brás; Joana Bravo; Mário Adolfo Barbosa; Susana Gomes Santos; Maria Ines Almeida. "TNF-Alpha-Induced Activation of Microglia Requires miR-342: Impact on NF-kB Signalling and Neurotoxicity". 2019.
    Published
  4. Summavielle, Teresa. "RhoGTPase regulation of redox homeostasis in microglia". Paper presented in Free Radical Biology and Medicine, Porto, 2019.
    Published
  5. Summavielle, Teresa. "RhoA signaling in microglia and the impact for neurodegeneration". Paper presented in Glia, Porto, 2019.
    Published
  6. Summavielle, Teresa. "Methamphetamine induced neuroimmune response: an interaction between astrocytes and microglia". Paper presented in Glia, Porto, 2019.
    Published
  7. Lobo, Andrea; Carvalhais, Lia; Terceiro, Ana F.; Magalhães, Ana; Garcia, Andreia; Socodato, Renato; Bettencourt Relvas, João; Summavielle, Teresa. "Psychostimulants induce neuronal remodeling via intersectin1-cdc42 pathway". Paper presented in SPN2019 - Meeting of the Portuguese Society for Neurosciences, Lisboa, 2019.
    Published
  8. Summavielle, Teresa. "Psychostimulant abuse and neuroinflammation: a crosstalk between glial cells and neurons". Paper presented in Glia, Porto, 2019.
    Published
  9. Alves, Renata; Santos, A.; Polonia, I.; Summavielle, Teresa; Magalhães, Ana. "Light cycle and cage change: behavioural effects over two different mice strains". Paper presented in Laboratory Animals, 2019.
    Published
  10. Summavielle, Teresa. "Exploring the role of miRNAs on microglia activation". Paper presented in HUMAN GENE THERAPY, 2018.
    Published
  11. Summavielle, Teresa. "Unmasking the impact of methylphenidate on blood-brain barrier function: in vitro and animal studies". Paper presented in FEBS OPEN BIO, 2018.
    Published
  12. Summavielle, Teresa. "Molecular mechanisms regulating glia homeostasis". Paper presented in Free Radical Biology and Medicine, 2018.
    Published
  13. Summavielle, Teresa. "Peripheric metabolic abnormalities in schizophrenia patients". Paper presented in European Psychiatry, 2017.
    Published
  14. Magalhães, Ana; Valentim, Ana M; Pereira, M.; Melo, P; Venâncio, C.; Summavielle, Teresa; Antunes, LM; et al. "Is ketamine alone or combined with midazolam or dexmedetomidine a good anaesthetic to use in biomedical research that requires behavioural evaluation?". Paper presented in 12th FELASA SECAL Congress, Barcelona, 2013.
    Published
  15. Valentim, A.; Magalhães, A.; Venâncio, C; Summavielle, Teresa; Antunes, Luis. "Is ketamine alone and in combination with midazolam or dexmedetomidine safe regarding post-anaesthetic memory?". Paper presented in Euroanaesthesia 2013 Congress, Barcelona, Spain, 01 - 04 June, European Journal of Anaesthesiology,, 2013.
    Published
  16. Venâncio, C.; Félix, L.; Antunes, L.; Summavielle, Teresa; Peixoto, F.. "Rat liver mitochondrial complex I impairment after chronic ketamine treatments.". Paper presented in Euroanaesthesia 2012 ¿ The European Anaesthesiology Congress - European Journal of Anaesthesiology, Paris, 2012.
    Published
  17. Venâncio, C.; Peixoto, F.; Antunes, L.; Summavielle, Teresa. "Mitochondrial Function Following Ketamine Chronic Treatments.". Paper presented in 2011 Annual Meeting of the American Society Anesthesiologists, Chicago, 2011.
    Published
  18. Venâncio, C; Almeida, V.; Peixoto, F.; Antunes, L.; Summavielle, Teresa. "Anesthetic doses of ketamine increase superoxide dismutase (SOD) activity in the brain of rats.". Paper presented in 2010 Annual Meeting of the American Society Anesthesiologists, San Diego, 2010.
    Published
  19. Venâncio, C.; Fernades, S.; Antunes, L.; Summavielle, Teresa; Magalhães, A.. "Chronic analgesic doses of ketamine increased thalamus cell death and induced abnormal spatial behavior in adult rats.". Paper presented in 6th EuroNeuro Congress - European Society of Anaesthesiology - European Journal of Anaesthesiology, Porto, 2010.
    Published
  20. Venâncio, C.; Peixoto, F.; Firmino, A.; Summavielle, Teresa; Antunes, L. M.. "Evaluation of the rat mitochondrial function after chronic ketamine administration.". Paper presented in 2009 Annual Meeting of the American Society Anesthesiologists, New Orleans, 2009.
    Published
  21. Magalhães, Ana; Alves, C.J.; Summavielle, Teresa; de Sousa, L.; Tavares, M.A.. "Dopaminergic system response to an anxiogenic situation in rats chronically exposed to cocaine during adolescence". Paper presented in Neurotoxicology and Teratology, 2007.
    Published
  22. Alves, C.J.; Magalhães, Ana; Summavielle, Teresa; Tavares, M.A.; Monteiro, P.R.R. "Effects of chronic administration on behavior of adolescent rats in the Elevated Plus Maze.". Paper presented in Neurotoxicology and Teratology, 2006.
  23. Summavielle, Teresa; Magalhães, Ana; Alves, C.J.,; de Sousa, Liliana; Tavares, Maria Amélia. "The interaction of setononergic and dopaminergic systems in the developing rat after cocaine exposure". Paper presented in The Toxicologist, 2004.
    Published
  24. Magalhães, Ana; Summavielle, Teresa; de Sousa, L.,; Amélia Tavares, MD, PhD. "Effects of neonatal cocaine on the serotonin system and behavior in the developing rat". Paper presented in Neurotoxicology and Teratology, 2003.
    Published
  25. Magalhães, Ana; Summavielle, Teresa; Amélia Tavares, MD, PhD; de Sousa, Liliana. "Postnatal cocaine exposure and rearing effects on open-field behavior.". Paper presented in Neurotoxicology and Teratology, 2003.
    Published
  26. Magalhães, Ana; Summavielle, Teresa; Tavares, M.A.. "Open-field activity along the development of rats postnatally exposed to cocaine". Paper presented in Neurotoxicology, 2001.
    Published
Conference paper
  1. Alves, Cecília J; Rocha, Daniela; Summavielle, Teresa; Fidalgo Carvalho, Isabel; Lamghari, Meriem. "Hypothalamic NPY expression during bone regeneration.". Paper presented in Neuropeptides 2010 Conference: The 7th Joint Meeting of the European Neuropeptide Club and the American Summer Neuropeptide Conference 21¿24 June 2010 Pécs, Hungary, Pecs, 2010.
    Published
Conference poster
  1. Terceiro, Ana F.; Lobo, Andrea; Canedo, Teresa; Socodato, Renato; Carvalhais, Lia; Aroso, Miguel; Sousa, Mafalda; et al. "Rho GTPases in the spotlight: unveiling methamphetamine's effects on neuronal remodeling in the hippocampus". Paper presented in Neuroscience 2023, 2023.
  2. Terceiro, Ana F.; Canedo, Teresa; Silva, Ana I; Magalhães, Ana; Relvas, João B.; Summavielle, Teresa. "Methamphetamine activates rac1 in striatal microglia". Paper presented in VII Symposium of the Portuguese Glial Network, 2023.
  3. Margarida Rodrigues; Canedo, T.; Ana Filipa Terceiro; Joana Tedim-Moreira; Silva, Ana Isabel; Ana Magalhães; Bettencourt Relvas, João; Summavielle, Teresa. "Deciphering the astrocytic and synaptic changes under chronic alcohol exposure using a self-administration paradigm". Paper presented in 9th McBiology Symposium, 2023.
  4. Terceiro, Ana F.; Lobo, Andrea; Canedo, Teresa; Carvalhais, Lia; Aroso, Miguel; Sousa, Mafalda; Socodato, Renato; et al. "Methamphetamine-induced modulation of RhoGTPases in hippocampal neurons and microglia (Presented by A. Terceiro)". Paper presented in n FENS-Hertie Winter School on Neuro-Immune Interactions in Health and Disease, 2023.
  5. Joana Gomes Ribeiro; Joana E. Coelho; Inês Marques-Morgado; Martins, João; Sereno, José Vitor Oliveira; Summavielle, Teresa; Miguel Castelo Branco; Remondes, Miguel; Luísa V. Lopes. "Chasing the trace of opioid addiction in the memory system". Paper presented in XVII Meeting of the Portuguese Society for Neurosciences, 2021.
  6. Ana Isabel Silva; Carolina Pinto; Ana Filipa Terceiro; Teresa Canedo; Ana Magalhães; João Bettencourt Relvas; Margarida Saraiva; et al. "Psychostimulant-induced neuroinflammation: the protective role of IL-10". Paper presented in Portuguese Society for Neuroscience (SPN) 2021, Coimbra, Portugal, 2021.
  7. Lobo, Andrea; Ana Filipa Terceiro; Lia Carvalhais; Aroso, Miguel; Mafalda Sousa; Ana Magalhães; Aguiar, Paulo; et al. "Methamphetamine remodelling of hippocampal neurons is orchestrated via cdc42 pathway". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience - SPN2021, 2021.
  8. Abreu, Daniela; Gomes, Joana I.; Sottomayor, Mariana; Ribeiro, Filipa Ferreira; Vicente Miranda, Hugo; Marques, Marta C; Summavielle, Teresa; et al. "Astrocyte's dysregulation: a central hub in Alzheimer's disease pathophysiology?". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  9. Canedo, Teresa; Silva, Ana I.; Andrade, Elva B.; Almeida, Tiago O.; Pombinho, António R.; Maia, André F.; Bravo, Joana; et al. "Unveiling the mechanism of methamphetamine-induced neuroinflammarory response: focus on astrocyte to microglia glutamatergic signaling (Presented by T. Summavielle)". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  10. Gomes, João R.; Lobo, Andrea; Nogueira, Renata; Terceiro, Ana F.; Costelha, Susete; Lopes, Igor M.; Magalhães, Ana; Summavielle, Teresa; Saraiva, Maria J.. "Neuronal megalin mediates synaptic plasticity¿a novel mechanism underlying intellectual disabilities in megalin gene pathologies (Presented by J. Gomes)". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  11. Lobo, Andrea; Terceiro, Ana F.; Bettencourt Relvas, João; Summavielle, Teresa. "Psychostimulant effects on hippocampal neurons: from morphology to cytoskeleton remodelling (Presented by A. Terceiro)". Paper presented in iMed Conference 11.0, 2019.
  12. Portugal, Camila; Socodato, Renato; Canedo, Teresa; Henriques, Joana F.; Silva, Cátia M; Ferreira, Mélanie M.; Magalhães, João; et al. "Profilin-1 deficiency specifically in microglia leads to microglial dysfunction, blood-brain barrier disruption and changes im mice bahaviour". Paper presented in IV Portuguese Glial Networking, Glia Diversity in Neuromodulation and Neurodegeneration, 2019.
  13. Ribeiro, Inês; Bravo, Joana; Canedo, Teresa; Lopes, Cátia DF; Summavielle, Teresa. "Methamphetamine and neuroinflammation: unveiling the crosstalk between glial cells and neurons". Paper presented in XVI Meeting of Portuguese Society for Neuroscience, 2019.
  14. Chavarria, Daniel; Silva, Tiago; Summavielle, Teresa; Borges, Fernanda. "Development of Novel Neuroprotective Antioxidants Inspired on Hydroxycinnamic Acid Scaffold". Paper presented in V Meeting of the Paul Ehrlich MedChem Euro-PhD Network, Krakow, Poland, 2015.
  15. Chavarria, Daniel; Silva, Tiago; Summavielle, Teresa; Borges, Fernanda. "Neuroprotective Properties of Lipophilic Antioxidants Based on Hydroxycinnamic Acid Template". Paper presented in 2nd Symposium on Medicinal Chemistry of University of Minho, Braga, Portugal., 2015.
  16. Coelho-Santos, Vanessa; Socodato, Renato; Portugal, Camila; Rito, Manuel; Barbosa, Marcos; Couraud, Pierre-Olivier; Romero, Ignacio A.; et al. "Unmasking the underlying mechanisms of methylphenidate effects on human brain endothelial cells". Paper presented in I Concurso Fundação AstraZeneca do IV In4Med, 2015.
  17. Coelho-Santos, Vanessa; Socodato, Renato; Portugal, Camila; Rito, Manuel; Barbosa, Marcos; Couraud, Pierre-Olivier; Romero, Ignacio A.; et al. "Unravelling the effect of methylphenidate on human brain endothelial cells". Paper presented in 5th World Congress on ADHD, 2015.
  18. Coelho-Santos, Vanessa; Socodato, Renato; Portugal, Camila; Leitão, Ricardo Alexandre; Rito, Manuel; Barbosa, Marcos; Cardoso, Filipa L; et al. "Methylphenidate activates Src pathway leading to caveolae-mediated transcytosis in human brain endothelial cells". Paper presented in XIV Portuguese Society for Neurosciences, 2015.
Journal article
  1. Socodato, Renato; Almeida, Tiago O.; Portugal, Camila C.; Santos, Evelyn C.S.; Tedim-Moreira, Joana; Galvão-Ferreira, João; Canedo, Teresa; et al. "Microglial Rac1 is essential for experience-dependent brain plasticity and cognitive performance". Cell Reports 42 12 (2023): 113447. http://dx.doi.org/10.1016/j.celrep.2023.113447.
    10.1016/j.celrep.2023.113447
  2. Bravo, Joana; Magalhães, Catarina; Andrade, Elva B.; Magalhães, Ana; Summavielle, Teresa. "The impact of psychostimulants on central and peripheral neuro-immune regulation: a scoping review of cytokine profiles and their implications for addiction". Frontiers in Cellular Neuroscience 17 (2023): http://dx.doi.org/10.3389/fncel.2023.1109611.
    10.3389/fncel.2023.1109611
  3. Vaz, Mariana; Summavielle, Teresa; Sebastião, Raquel; Ribeiro, Rita P.. "Multimodal Classification of Anxiety Based on Physiological Signals". Applied Sciences 13 11 (2023): 6368. http://dx.doi.org/10.3390/app13116368.
    10.3390/app13116368
  4. Alves, Renata L.; Portugal, Camila C.; Lopes, Igor M.; Oliveira, Pedro; Alves, Cecília J.; Barbosa, Fernando; Summavielle, Teresa; Magalhães, Ana. "Maternal stress and vulnerability to depression: coping and maternal care strategies and its consequences on adolescent offspring". Translational Psychiatry 12 1 (2022): http://dx.doi.org/10.1038/s41398-022-02220-5.
    10.1038/s41398-022-02220-5
  5. Joana Bravo; Inês Ribeiro; Ana Filipa Terceiro; Elva B. Andrade; Camila Cabral Portugal ; Igor M. Lopes ; Maria Azevedo; et al. Corresponding author: Summavielle, Teresa. "Neuron-microglia contact dependent mechanisms attenuate methamphetamine-induced microglia reactivity and enhance neuronal plasticity". Cells 11 3 (2022): https://www.mdpi.com/2073-4409/11/3/355.
    Accepted • https://doi.org/10.3390/cells11030355
  6. Ana Bela Campos; Sara Duarte-Silva; Bruno Fernandes; Sofia Pereira das Neves; Fernanda Marques; Andreia Teixeira-Castro; Andreia Neves-Carvalho; et al. "Profiling Microglia in a Mouse Model of Machado–Joseph Disease". Biomedicines (2022): https://www.mdpi.com/2227-9059/10/2/237.
    10.3390/biomedicines10020237
  7. Joana Bravo; Ines Ribeiro; Ana Filipa Terceiro; Elva Bonifácio Andrade; Camila Portugal; Igor Moreira Lopes; Maria M. Azevedo; et al. "Neuron–Microglia Contact-Dependent Mechanisms Attenuate Methamphetamine-Induced Microglia Reactivity and Enhance Neuronal Plasticity". Cells (2022): https://www.mdpi.com/2073-4409/11/3/355.
    10.3390/cells11030355
  8. Soares NL; Paiva I; Bravo J; Queiroga CSF; Melo BF; Conde SV; Romão CC; Summavielle T; Vieira HLA. "Carbon Monoxide Modulation of Microglia-Neuron Communication: Anti-Neuroinflammatory and Neurotrophic Role.". Molecular neurobiology (2021): http://europepmc.org/abstract/med/34796462.
    10.1007/s12035-021-02643-z
  9. Canedo T; Portugal CC; Socodato R; Almeida TO; Terceiro AF; Bravo J; Silva AI; et al. "Astrocyte-derived TNF and glutamate critically modulate microglia activation by methamphetamine.". Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (2021): http://europepmc.org/abstract/med/34400780.
    10.1038/s41386-021-01139-7
  10. Summavielle, Teresa. "Altered environmental perception by parental stress and depression vulnerability: impact on mothers and offspring". - (2021): bioRxiv 2021.02.23.432580.
    Submitted • doi: https://doi.org/10.1101/2021.02.23.432580
  11. Renato Socodato; Joana F. Henriques; Camila C. Portugal; Tiago O. Almeida; Joana Tedim-Moreira; Renata L. Alves; Teresa Canedo; et al. "Daily alcohol intake triggers aberrant synaptic pruning leading to synapse loss and anxiety-like behavior". Science Signaling 13 650 (2020): eaba5754. https://doi.org/10.1126/scisignal.aba5754.
    Published • 10.1126/scisignal.aba5754
  12. João R Gomes; Andrea Lobo; Renata Nogueira; Ana F Terceiro; Susete Costelha; Igor M Lopes; Ana Magalhães; et al. "Neuronal megalin mediates synaptic plasticity—a novel mechanism underlying intellectual disabilities in megalin gene pathologies". Brain Communications (2020): fcaa135. https://doi.org/10.1093/braincomms/fcaa135.
    Published • 10.1093/braincomms/fcaa135
  13. Socodato, Renato; Portugal, Camila C.; Canedo, Teresa; Rodrigues, Artur; Almeida, Tiago O.; Henriques, Joana F.; Vaz, Sandra H.; et al. "Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration". Cell Reports 31 12 (2020): 107796. http://dx.doi.org/10.1016/j.celrep.2020.107796.
    Published • 10.1016/j.celrep.2020.107796
  14. Brás, João Paulo; Bravo, Joana; Freitas, Jaime; Barbosa, Mário Adolfo; Santos, Susana Gomes; Summavielle, Teresa; Almeida, Maria Inês. "TNF-alpha-induced microglia activation requires miR-342: impact on NF-kB signaling and neurotoxicity". Cell Death & Disease 11 6 (2020): http://dx.doi.org/10.1038/s41419-020-2626-6.
    Open access • Published • 10.1038/s41419-020-2626-6
  15. Alves, R.L.; Oliveira, P.; Lopes, I.M.; Portugal, C.C.; Alves, C.J.; Barbosa, F.; Summavielle, T.; Magalhães, A.. "Early-life stress affects drug abuse susceptibility in adolescent rat model independently of depression vulnerability". Scientific Reports 10 1 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85089153440&partnerID=MN8TOARS.
    Open access • Published • 10.1038/s41598-020-70242-4
  16. Carvalheiro, Joana; Seara-Cardoso, Ana; Mesquita, Ana Raquel; de Sousa, Liliana; Oliveira, Pedro; Summavielle, Teresa; Magalhães, Ana. "Helping behavior in rats (Rattus norvegicus) when an escape alternative is present.". Journal of Comparative Psychology 133 4 (2019): 452-462. http://dx.doi.org/10.1037/com0000178.
    Published • 10.1037/com0000178
  17. Alves, Renata L.; Portugal, Camila Cabral; Summavielle, Teresa; Barbosa, Fernando; Magalhães, Ana. "Maternal separation effects on mother rodents’ behaviour: A systematic review". Neuroscience & Biobehavioral Reviews (2019): http://dx.doi.org/10.1016/j.neubiorev.2019.09.008.
    Published • 10.1016/j.neubiorev.2019.09.008
  18. Andrade, Elva Bonifácio; Magalhães, Ana; Puga, Ana; Costa, Madalena; Bravo, Joana; Portugal, Camila Cabral; Ribeiro, Adília; et al. "A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection". Nature Communications 9 1 (2018): 3138-3151. http://dx.doi.org/10.1038/s41467-018-05492-y.
    Open access • Published • 10.1038/s41467-018-05492-y
  19. Amorim, Manuela; Bravo, Joana; Silva, Ana Isabel; Juliana Alves, CecA­lia; Monteiro, Pedro RR; MagalhAEes, Ana; Summavielle, Teresa. "Repeated Exposure to Ketamine in Adolescent Rats Results in Persistent Anxiety in the Adulthood". Journal of Drug and Alcohol Research 07 01 (2018): 1-10. http://dx.doi.org/10.4303/jdar/236060.
    Published • 10.4303/jdar/236060
  20. Henriques, J.F.; Portugal, C.C.; Canedo, T.; Relvas, J.B.; Summavielle, T.; Socodato, R.. "Microglia and alcohol meet at the crossroads: Microglia as critical modulators of alcohol neurotoxicity". Toxicology Letters 283 (2018): 21-31. http://www.scopus.com/inward/record.url?eid=2-s2.0-85034097322&partnerID=MN8TOARS.
    Published • 10.1016/j.toxlet.2017.11.002
  21. Magalhães, A.; Valentim, A.; Venâncio, C.; Pereira, M.; Melo, P.; Summavielle, T.; Antunes, L.. "Ketamine alone or combined with midazolam or dexmedetomidine does not affect anxiety-like behaviours and memory in adult wistar rats". Laboratory Animals 51 2 (2017): 147-159. http://www.scopus.com/inward/record.url?eid=2-s2.0-85018396469&partnerID=MN8TOARS.
    Published • 10.1177/0023677216652380
  22. Braz, S.O.; Cruz, A.; Lobo, A.; Bravo, J.; Moreira-Ribeiro, J.; Pereira-Castro, I.; Freitas, J.; et al. "Expression of Rac1 alternative 3' UTRs is a cell specific mechanism with a function in dendrite outgrowth in cortical neurons". Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1860 6 (2017): 685-694. http://www.scopus.com/inward/record.url?eid=2-s2.0-85018940086&partnerID=MN8TOARS.
    Published • 10.1016/j.bbagrm.2017.03.002
  23. Coelho-Santos, V.; Socodato, R.; Portugal, C.; Leitão, R.A.; Rito, M.; Barbosa, M.; Couraud, P.-O.; et al. "Methylphenidate-triggered ROS generation promotes caveolae-mediated transcytosis via Rac1 signaling and c-Src-dependent caveolin-1 phosphorylation in human brain endothelial cells". Cellular and Molecular Life Sciences 73 24 (2016): 4701-4716. http://www.scopus.com/inward/record.url?eid=2-s2.0-84976878471&partnerID=MN8TOARS.
    Published • 10.1007/s00018-016-2301-3
  24. Alves, C.J.; Alencastre, I.S.; Neto, E.; Ribas, J.; Ferreira, S.; Vasconcelos, D.M.; Sousa, D.M.; Summavielle, T.; Lamghari, M.. "Bone injury and repair trigger central and peripheral NPY neuronal pathways". PLoS ONE 11 11 (2016): e0165465. http://www.scopus.com/inward/record.url?eid=2-s2.0-84993996075&partnerID=MN8TOARS.
    Open access • Published • 10.1371/journal.pone.0165465
  25. Fernandes, S.; Salta, S.; Bravo, J.; Silva, A.P.; Summavielle, T.. "Acetyl-L-Carnitine Prevents Methamphetamine-Induced Structural Damage on Endothelial Cells via ILK-Related MMP-9 Activity". Molecular Neurobiology 53 1 (2016): 408-422. http://www.scopus.com/inward/record.url?eid=2-s2.0-84914140189&partnerID=MN8TOARS.
    Published • 10.1007/s12035-014-8973-5
  26. Summavielle, T.; Venâncio, C.; Antunes, L.; Summavielle, Teresa; Venâncio, Carlos; Antunes, Luís. "In Response". Anesthesia and Analgesia 122 3 (2016): 918-920. http://www.scopus.com/inward/record.url?eid=2-s2.0-84959042892&partnerID=MN8TOARS.
    Published • 10.1213/ANE.0000000000001001
  27. Teixeira-Castro, A.; Jalles, A.; Esteves, S.; Kang, S.; Da Silva Santos, L.; Silva-Fernandes, A.; Neto, M.F.; et al. "Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease". Brain 138 11 (2015): 3221-3237. http://www.scopus.com/inward/record.url?eid=2-s2.0-84947806720&partnerID=MN8TOARS.
    Published • 10.1093/brain/awv262
  28. Venâncio, C.; Félix, L.; Almeida, V.; Coutinho, J.; Antunes, L.; Peixoto, F.; Summavielle, T.. "Acute ketamine impairs mitochondrial function and promotes superoxide dismutase activity in the rat brain". Anesthesia and Analgesia 120 2 (2015): 320-328. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922337300&partnerID=MN8TOARS.
    Published • 10.1213/ANE.0000000000000539
  29. Fernandes, S.; Salta, S.; Summavielle, T.. "Methamphetamine promotes a-tubulin deacetylation in endothelial cells: The protective role of acetyl-l-carnitine". Toxicology Letters 234 2 (2015): 131-138. http://www.scopus.com/inward/record.url?eid=2-s2.0-84923364136&partnerID=MN8TOARS.
    Published • 10.1016/j.toxlet.2015.02.011
  30. Silva, T.; Bravo, J.; Summavielle, T.; Remião, F.; Pérez, C.; Gil, C.; Martínez, A.; Borges, F.. "Biology-oriented development of novel lipophilic antioxidants with neuroprotective activity". RSC Advances 5 21 (2015): 15800-15811. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922828018&partnerID=MN8TOARS.
    Published • 10.1039/c4ra15164j
  31. Chavarria, Daniel; Silva, Tiago; Martins, Daniel; Bravo, Joana; Summavielle, Teresa; Garrido, Jorge; Borges, Fernanda; et al. "Exploring cinnamic acid scaffold: development of promising neuroprotective lipophilic antioxidants". Med. Chem. Commun. 6 6 (2015): 1043-1053. http://hdl.handle.net/10400.22/7481.
    Published • 10.1039/C5MD00018A
  32. Cunha, L.; Horvath, I.; Ferreira, S.; Lemos, J.; Costa, P.; Vieira, D.; Veres, D.S.; et al. "Preclinical imaging: An essential ally in modern biosciences". Molecular Diagnosis and Therapy 18 2 (2014): 153-173. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897397513&partnerID=MN8TOARS.
    Published • 10.1007/s40291-013-0062-3
  33. Alves, C.J.; Magalhães, A.; Melo, P.; de Sousa, L.; Tavares, M.A.; Monteiro, P.R.R.; Summavielle, T.. "Long-term effects of chronic cocaine exposure throughout adolescence on anxiety and stress responsivity in a Wistar rat model". Neuroscience 277 (2014): 343-355. http://www.scopus.com/inward/record.url?eid=2-s2.0-84905366454&partnerID=MN8TOARS.
    Published • 10.1016/j.neuroscience.2014.07.008
  34. Venâncio, C.; Antunes, L.; Félix, L.; Rodrigues, P.; Summavielle, T.; Peixoto, F.. "Chronic ketamine administration impairs mitochondrial complex i in the rat liver". Life Sciences 93 12-14 (2013): 464-470. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884202630&partnerID=MN8TOARS.
    Published • 10.1016/j.lfs.2013.08.001
  35. Ribeiro Do Couto, B.; Daza-Losada, M.; Rodríguez-Arias, M.; Nadal, R.; Guerri, C.; Summavielle, T.; Miñarro, J.; Aguilar, M.A.. "Adolescent pre-exposure to ethanol and 3,4-methylenedioxymethylamphetamine (MDMA) increases conditioned rewarding effects of MDMA and drug-induced reinstatement". Addiction Biology 17 3 (2012): 588-600. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860240599&partnerID=MN8TOARS.
    10.1111/j.1369-1600.2011.00382.x
  36. Valentim, A.M.; Vengncio, C.; Summavielle, T.; Antunes, L.M.. "Importance of body temperature and clinical data in behavioral and anesthesia studies". Anesthesiology 116 1 (2012): 226-227. http://www.scopus.com/inward/record.url?eid=2-s2.0-84555218001&partnerID=MN8TOARS.
    Published • 10.1097/ALN.0b013e31823cf056
  37. Melo, P.; Magalhães, A.; Alves, C.J.; Tavares, M.A.; de Sousa, L.; Summavielle, T.; Moradas-Ferreira, P.. "Methamphetamine mimics the neurochemical profile of aging in rats and impairs recognition memory". NeuroToxicology 33 3 (2012): 491-499. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861188767&partnerID=MN8TOARS.
    Published • 10.1016/j.neuro.2012.03.002
  38. Baptista, S.; Bento, A.R.; Gonçalves, J.; Bernardino, L.; Summavielle, T.; Lobo, A.; Fontes-Ribeiro, C.; et al. "Neuropeptide Y promotes neurogenesis and protection against methamphetamine-induced toxicity in mouse dentate gyrus-derived neurosphere cultures.". Neuropharmacology 62 7 (2012): 2413-2423. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871869687&partnerID=MN8TOARS.
    Published • 10.1016/j.neuropharm.2012.02.015
  39. Venâncio, C.; Magalhães, A.; Antunes, L.; Summavielle, T.. "Impaired spatial memory after ketamine administration in chronic low doses". Current Neuropharmacology 9 1 (2011): 251-255. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953036071&partnerID=MN8TOARS.
    Published • 10.2174/157015911795016912
  40. Santos, M.; Summavielle, T.; Teixeira-Castro, A.; Silva-Fernandes, A.; Duarte-Silva, S.; Marques, F.; Martins, L.; et al. "Monoamine deficits in the brain of methyl-CpG binding protein 2 null mice suggest the involvement of the cerebral cortex in early stages of Rett syndrome". Neuroscience 170 2 (2010): 453-467. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956186732&partnerID=MN8TOARS.
    Published • 10.1016/j.neuroscience.2010.07.010
  41. Alves, E.; Summavielle, T.; Alves, C.J.; Custódio, J.B.A.; Fernandes, E.; De Lourdes Bastos, M.; Tavares, M.A.; Carvalho, F.. "Ecstasy-induced oxidative stress to adolescent rat brain mitochondria in vivo: Influence of monoamine oxidase type A". Addiction Biology 14 2 (2009): 185-193. http://www.scopus.com/inward/record.url?eid=2-s2.0-61849137910&partnerID=MN8TOARS.
    Published • 10.1111/j.1369-1600.2008.00143.x
  42. Alves, E.; Binienda, Z.; Carvalho, F.; Alves, C.J.; Fernandes, E.; de Lourdes Bastos, M.; Tavares, M.A.; Summavielle, T.. "Acetyl-l-carnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain". Neuroscience 158 2 (2009): 514-523. http://www.scopus.com/inward/record.url?eid=2-s2.0-58149463913&partnerID=MN8TOARS.
    Published • 10.1016/j.neuroscience.2008.10.041
  43. Alves, C.J.; Magalhães, A.; Summavielle, T.; Melo, P.; De Sousa, L.; Tavares, M.A.; Monteiro, P.R.R.. "Hormonal, neurochemical, and behavioral response to a forced swim test in adolescent rats throughout cocaine withdrawal". Annals of the New York Academy of Sciences 1139 (2008): 366-373. http://www.scopus.com/inward/record.url?eid=2-s2.0-53549107231&partnerID=MN8TOARS.
    Published • 10.1196/annals.1432.047
  44. Magalhães, A.; Melo, P.; Alves, C.J.; Tavares, M.A.; De Sousa, L.; Summavielle, T.. "Exploratory behavior in rats postnatally exposed to cocaine and housed in an enriched environment". Annals of the New York Academy of Sciences 1139 (2008): 358-365. http://www.scopus.com/inward/record.url?eid=2-s2.0-53549102243&partnerID=MN8TOARS.
    Published • 10.1196/annals.1432.046
  45. Alves, E.; Summavielle, T.; Alves, C.J.; Gomes-da-Silva, J.; Barata, J.C.; Fernandes, E.; Bastos, M.D.L.; Tavares, M.A.; Carvalho, F.. "Monoamine oxidase-B mediates ecstasy-induced neurotoxic effects to adolescent rat brain mitochondria". Journal of Neuroscience 27 38 (2007): 10203-10210. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548842751&partnerID=MN8TOARS.
    Published • 10.1523/JNEUROSCI.2645-07.2007
  46. Mesquita, A.R.; Pêgo, J.M.; Summavielle, T.; Maciel, P.; Almeida, O.F.X.; Sousa, N.. "Neurodevelopment milestone abnormalities in rats exposed to stress in early life". Neuroscience 147 4 (2007): 1022-1033. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547102233&partnerID=MN8TOARS.
    10.1016/j.neuroscience.2007.04.007
  47. Magalhães, A.; Summavielle, T.; Tavares, M.A.; De Sousa, L.. "Postnatal exposure to cocaine in rats housed in an enriched environment: Effects on social interactions". Human and Experimental Toxicology 26 4 (2007): 303-309. http://www.scopus.com/inward/record.url?eid=2-s2.0-34248345906&partnerID=MN8TOARS.
    10.1177/0960327106070458
  48. Faria, R.; Magalhães, A.; Monteiro, P.R.R.; Gomes-Da-Silva, J.; Tavares, M.A.; Summavielle, T.. "MDMA in adolescent male rats: Decreased serotonin in the amygdala and behavioral effects in the elevated plus-maze test". Annals of the New York Academy of Sciences 1074 (2006): 643-649. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749555776&partnerID=MN8TOARS.
    Published • 10.1196/annals.1369.062
  49. Magalhães, A.; Summavielle, T.; Melo, P.; Rosa, R.; Tavares, M.A.; De Sousa, L.. "Prenatal exposure to cocaine and enriched environment: Effects on social interactions". Annals of the New York Academy of Sciences 1074 (2006): 620-631. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749542491&partnerID=MN8TOARS.
    Published • 10.1196/annals.1369.060
  50. Magalhães, A.; Summavielle, T.; Melo, P.; Tavares, M.A.; De Sousa, L.. "Prenatal cocaine exposure: Effects on locomotor activity in rat offspring". Environmental Toxicology and Pharmacology 19 3 (2005): 767-773. http://www.scopus.com/inward/record.url?eid=2-s2.0-17044425030&partnerID=MN8TOARS.
    Published • 10.1016/j.etap.2004.12.043
  51. Magalhães, A.; Summavielle, T.; Tavares, M.A.; De Sousa, L.. "Effects of postnatal cocaine exposure and environmental enrichment on rat behavior in a forced swim test". Environmental Toxicology and Pharmacology 1025 (2004): 619-629. http://www.scopus.com/inward/record.url?eid=2-s2.0-10444275641&partnerID=MN8TOARS.
    Published • 10.1196/annals.1316.077
  52. Summavielle, T.; Alves, C.J.; Monteiro, P.R.R.; Tavares, M.A.. "Abnormal immunoreactivity to serotonin in cerebellar purkinje cells after neonatal cocaine exposure". Environmental Toxicology and Pharmacology 1025 (2004): 630-637. http://www.scopus.com/inward/record.url?eid=2-s2.0-10444279249&partnerID=MN8TOARS.
    Published • 10.1196/annals.1316.078
  53. Gomes-Da-Silva, J.; De Miguel, R.; Fernández-Ruiz, J.; Summavielle, T.; Tavares, M.A.. "Effects of neonatal exposure to methamphetamine: Catecholamine levels in brain areas of the developing rat". Annals of the New York Academy of Sciences 1025 (2004): 602-611. http://www.scopus.com/inward/record.url?eid=2-s2.0-10444268132&partnerID=MN8TOARS.
    Published • 10.1196/annals.1316.075
  54. Summavielle, T.; Monteiro, P.R.R.; Reis-Henriques, M.A.; Coimbra, J.. "In vitro metabolism of steroid hormones by ovary and hepatopancreas of the crustacean Penaeid shrimp Marsupenaeus japonicus". Scientia Marina 67 3 (2003): 299-306. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242498770&partnerID=MN8TOARS.
  55. Tavares, Maria Amélia; Castro Vale, Ivone; Magalhães, Ana; Summavielle, Teresa; de Sousa, Liliana. "Abordagem Multidisciplinar do Complexo Amigdalóide do Rato Exposto à Cocaína: Modelo de Neurotoxicologia Experimental no Desenvolvimento". TOXICODEPENDÊNCIAS ¿Edição IDT 9 1 (2003): 3-27. http://www.sicad.pt/BK/RevistaToxicodependencias/Lists/SICAD_Artigos/Attachments/165/2003_01_TXT1.pdf.
    Published
  56. Summavielle, T.; Magalhães, A.; Castro-Vale, I.; De Sousa, L.; Tavares, M.A.. "Neonatal exposure to cocaine: Altered dopamine levels in the amygdala and behavioral outcomes in the developing rat". Annals of the New York Academy of Sciences 965 1 (2002): 515-521. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036290213&partnerID=MN8TOARS.
    Published
  57. Summavielle, T.; Silva-ARAÚJO, A.; Silva, M.C.; Tavares, M.A.. "Effects of neonatal exposure to cocaine in the development of the neurotransmitters retinal systems: An immunocytochemical and neurochemical study". Annals of the New York Academy of Sciences 914 (2000): 418-430. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033695142&partnerID=MN8TOARS.
    Published
Magazine article
  1. Summavielle, Teresa; Filomena Nave. "Tecnologias mostram o cérebro a sorrir", DN Life, 2019, https://life.dn.pt/comportamento/como-as-novas-tecnologias-mostram-o-cerebro-a-sorrir/?fbclid=IwAR2-6fjq8WPUwy8nUuDJuisaMTZX1lUCrB0xE_mJDff97eTf_RAd0kzJ7z8.
Newspaper article
  1. Summavielle, Teresa. "A precariedade mora aqui", Público, 2019, Opinion, https://www.publico.pt/2019/09/18/ciencia/opiniao/precariedade-mora-aqui-1886966.
  2. Summavielle, Teresa. "A utopia da hospitalidade aplicada à universidade", Público, 2019, Opinion, https://www.publico.pt/2019/03/23/ciencia/opiniao/utopia-hospitalidade-aplicada-universidade-1866524.
  3. Summavielle, Teresa; Joao Santos Relvas. "Cannabis para uso terapêutico", Público, 2018, https://www.publico.pt/2018/04/15/sociedade/opiniao/canabis--uso-terapeutico-1810348#gs.kjXRr69I.
Preprint
  1. Evelyn C. S. Santos; Ana Filipa Terceiro; Rui Vitorino; Igor Lopes; Renata L. Alves; João B. Relvas; Teresa Summavielle; Ana Magalhães. "Prefrontal cortex proteomic alteration after social instability stress in adolescents rats". 2023. https://doi.org/10.1101/2023.05.08.539806.
    10.1101/2023.05.08.539806
  2. Socodato R; Almeida TO; Portugal CC; Santos ECS; Tedim-Moreira J; Canedo T; Baptista FI; et al. "Rac1 signaling in microglia is essential for synaptic proteome plasticity and experience-dependent cognitive performance". 2021. http://europepmc.org/abstract/PPR/PPR409062.
    10.1101/2021.10.18.464802
  3. Socodato, Renato; Henriques, Joana F.; Portugal, Camila C.; Almeida, Tiago O.; Tedim-Moreira, Joana; Alves, Renata L.; Canedo, Teresa; et al. "Alcohol intake triggers aberrant synaptic pruning leading to synapse loss and anxiety-like behavior". 2019. http://dx.doi.org/10.1101/870279.
    10.1101/870279
Working paper
  1. Lobo, Andrea; Summavielle, Teresa; Ana Isabel Ferreira de Magalhães Gamito Carrilho; Ana Filipa Martins Terceiro; Joao Carlos Bettencourt de Medeiros relvas. 2021. "Methamphetamine regulates neuronal remodeling and synaptic plasticity via Intersectin1-cdc42 pathway".
  2. Summavielle, Teresa. 2017. "Genetic ablation of RhoA in adult microglia causes synapse and neuronal loss". https://doi.org/10.1101%2F218107.
    10.1101/218107

Other

Other output
  1. Not so smart drugs. Not so smart drugs” - Scientific Coordination of a multidisciplinary team to create a simple tool for prevention of smart drug use. This initiative was part of the NERRI project (FP7), both a Portuguese a English version were made available.. 2017. Summavielle, Teresa. https://drive.google.com/file/d/1FzIVS-wAduwl6UvkAxfiaFSUnSC29UjR/view?usp=sharing.
  2. Protege o teu cérebro. Competition “Protege o teu cérebro” - Scientific Coordination. This initiative was part of the Brain Awareness Week (DANA). 2011. Summavielle, Teresa. http://www.ibmc.up.pt/cerebro/.
  3. e-drogas. Scientific coordination of “e-drogas”, a webpage that targets the adolescent population and was designed to inform on the consequences of drug use/abuse. This site also facilitates access to qualified health support. This webpage was sponsored by Fundação Calouste Gulbenkian and can be consulted at http://www.ibmc.up.pt/e-drogas. 2009. Summavielle, Teresa. http://e-drogas.blogspot.com/.
  4. Põe-te a Milhas das Pastilhas. Leads the project “Põe-te a Milhas das Pastilhas”, a communication project based on education that aims to prevent the use of illicit drugs among high-school students. The message is focused on the impact on brain function, emphasizing the long-term consequences. It has reached close to 20 000 students in high-schools from the Porto’s metropolitan area. This project was initially supported by FCG.. 2008. Summavielle, Teresa. https://i3sedu.wordpress.com/projectos/poe-te-a-milhas-das-pastilhas/.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/12/05 Desafios e constrangimentos à política de Ciência em Portugal Ciencias, humanidade e sociedade
Academia de Ciências (Lisboa, Portugal)
2023/11/23 Quão longe poderemos ir explorando o papel das citocinas na dependência? / How far can cytokines take us in a context of addiction? XVII Congresso Nacional de Psiquiatria (CNP)
Portuguese Society of Psychiatry and Mental Health (Portugal)
2023/10/10 Conferência inaugural – O CÉREBRO DEPENDENTE EM VERSÃO NEUROIMUNE 2nd National Encounter of CAD
SICAD (Aveiro, Portugal)
2023/09 PsychoGlia: a tale of neurons, drugs and glia ICVS Seminars
ICVS, University of Minho (Braga, Portugal)
2023/05 Os efeitos epigenéticos do uso de substâncias psicoactivas O cérebro e a vontade
Associação Portuguesa de Adictologia – Associação para o Estudo das Drogas e das Dependências (Coimbra, Portugal)
2023/04 PsychoGlia, sex differences in the fate of glial cells under psychostimulants Heterogeneity of glial cells - sex-sensitive communication between cells and organs - Homburg Spring Symposium
Homburg University (Homburg, Germany)
2022/11 Binge alcohol intake triggers microglial activation and TNF-dependent aberrant synaptic pruning, causing synapse loss and increased anxiety 4th Lisbon Addiction conference
SICAD (Lisboa, Portugal)
2022/06/17 The future of drug reforms: how to regulate the substance use in the 21st century PTMC – Portugal Medical Cannabis
PTMC (Lisboa, Portugal)
2022/03/09 PsychoGlia - a fronteira entre o cérebro e o sistema imunitário Brain Gain
University of Coimbre (Coimbra, Portugal)
2022/01 Em busca de novas abordagens terapêuticas para a dependência. Biotech and Beyond
ESS.PP (Porto)
2021/11/30 PsychoGlia: a crosstalk between glial cells under psychoactive drugs NetworkGlia Meeting
University of Coimbra (Coimbra, Portugal)
2021/03/12 Exploring glial cells in drug context VI SBE – Bioengineering Week 2021
IST (Lisboa, Portugal)
2021/01/18 Neuroinflammation and substance abuse: partners in crime Neuroscience seminars
Lisbon Medical School (Lisboa, Portugal)
2020/11/17 A relevância da regulação neuroimune no comportamento aditivo (The relevance of neuroinflammation for the addictive behaviour) - DICAD conferences (National Health System) DICAD conferences
DICAS (National Health System) (Porto, Portugal)
2020/11/14 O papel da neuroinflamação no comportamento adictivo. (The role of neuroinflammation in substance abuse) XV Congresso da AEFFUP
Faculty of Pharmacy- Student Nucleus (Porto, Portugal)
2020/07 Ensino e Investigação. Recrutamento e progressão. (Academic careers entrance and progression) University of Coimbra Ciclo de Conferências “Repensar o RJIES” (Conference cycle "Rethinking the University Juridic Regimen"
University of Coimbra (Coimbra, Portugal)
2019/11/06 Breaking Barriers - Cannabis in Modern Medicine and Society: Science is the best advocate Berlin Science Week
https://berlinscienceweek.com/programme/breaking-barriers-cannabis-in-modern-medicine-and-society (Berlin, Germany)
2019/10/23 An astrocyte-microglia crosstalk mediating neuroinflammation under exposure to psychostimulants 3rd Lisbon Addictions conference
SICAD (Lisboa, Portugal)
2019/10/23 Role of cytoskeleton regulation in methamphetamine induced changes on the hippocampal neuronal morphology 3rd Lisbon Addictions conference
SICAD (Lisboa, Portugal)
2019/07/03 Precariedade na Investigação (Science as a precarious job) INVESTIGAÇÃO DOCÊNCIA E FORMAÇÃO: QUE DESAFIOS PARAASUNIVERSIDADES ECENTROS DE INVESTIGAÇÃO?
Universidade de Coimbra, Centro de Estudos Sociais (Porto, Portugal)
2019/06/19 Uma Universidade nas nossas mãos (The University in our hands) Universidade: do conceito à concretização do ontem ao amanhã
UTAD (Vila Real, Portugal)
2019/06/06 Factos e mitos no uso de cannabis As vertigens do Risco e os Labirintos da Vontade Olhares sobre Comportamentos Aditivos
Jornadas da Associação Portuguesa Adictologia (Coimbra, Portugal)
2019/05/29 “TNF and glutamate dependent microglia reactivity under a psychoactive drug Glia Diversity in Neuromodulation and Neurodegeneration. IV Symposium
Portuguese Glial Network (Lisboa, Portugal)
2019/05/16 The influence of science in Drug Addiction policy: the Portuguese case Debate – How to influence through Science Policy: Who, What and Why
Transpeer - A Transnational Project to Enhance Researcher Employability (Lisboa, Portugal)
2019/05/02 Psychostimulant-elicited synaptic modulation through regulation of Cdc42 UCL-Discoveries Centre, Synaptic Function, Dysfunction and Repair Workshop
CEDOC and UCL- Discoveries Centre (Lisboa, Portugal)
2019/03/17 Neuroinflammation and drug addiction, partners in crime? X National Event for Biomedical Sciences (JNBC),
Univ. Aveiro (Aveiro, Portugal)
2019/03/15 The therapeutic potential of cannabis VII AEICBAS Biomedical Congress (ABC),
Medical Students ICBAS, Univ. Porto (Porto, Portugal)
2019/03/15 Smart Drugs, Nootropic and Brain Enhancers VII AEICBAS Biomedical Congress (ABC),
Medical Students ICBAS Univ.of Porto (Porto, Portugal)
2019/03/12 Who's in charge at the addicted brain? Opening of the Brain Awareness Week
Medical School of Porto (Porto, Portugal)
2018/11/08 Nicotine and cannabinoids, a complex cross-talk 34º Congresso da Sociedade Portuguesa de Pneumologia
Sociedade Portuguesa de Pneumologia (Algarve, Portugal)
2018/10/27 Smart Drugs, Nootropic and Brain Enhancers V Congresso National de Estudantes de Medicina
CNEM (Porto, Portugal)
2018/05/17 Padrões de exposição binge e desregulação neuroimune Encontro de Adições de Cascais
(Cascais, Portugal)
2018/05/15 Not so smart drugs A Pint of Science
(Porto, Portugal)
2018/03/17 Legalizing cannabis 6th AEICBAS Biomedical Congress
AEICBAS (Porto, Portugal)
2018/03/14 Neuroinflamação na exposição a psicoestimulantes: uma conversa cruzada entre neurónios e glia Seminário FMUP
FMUP (Porto, Portugal)
2017/06/21 The adolescente brain under drug abuse 35th Youth Science Meeting
(Porto, Portugal)
2017/05/24 New insights on psychostimulant regulation of microglia activation II Glia meeting
ICVS (Braga, Portugal)
2017/03/09 The addicted brain: a neuronal disease or a crosstalk between different neuronal players? IV AEICBAS Biomedical Conference
AEICBAS (Porto, Portugal)
2017/03/09 O cérebro adolescente e os compostos psicoactivos Dias da psicologia
FEP, Universidade Católica (Porto, Portugal)
2016/06/06 Facts and myths on cannabis use Portuguese Society for Addiction
Portuguese Society for Addiction (Coimbra, Portugal)
2016/05/20 Genes, cérebro e substâncias psicoativas GAF
GAF (Viana do Castelo, Portugal)
2016/03/16 Drug addiction: methods in Neuroscience III Cognition, Emotion, Behaviour - The Brain at Work
FPCEUP (Porto, Portugal)
2016/03/11 Not so smart drugs II Simpósio do Programa Doutoral em Psicologia
FPCEUP (Porto, Portugal)
2015/10/15 The adolescent brain under drug of abuse Opening year conference, Instituto Superior de Serviço Social do Porto (ISSS)
ISSS (Porto, Portugal)
2015/09/24 Methamphetamine-induced changes in hippocampal neurons morphology is mediated by Rac1 activation I Lisbon Addiction
SICAD (Lisboa, Portugal)
2015/09/06 Methamphetamine at the cytoskeletal level: molecular, morphologic and behavioural effects CNC.IBILI Seminars
CNC (Coimbra, Portugal)
2015/05/13 The adolescent brain under drug of abuse PhD Honor Lectures 2015
Dep. of Basic Psychology (Braga, Portugal)
2015/05/13 O cérebro Adolescente e o consumo de substâncias psicoativas B fora da caixa
XVI Jornadas de Biologia Aplicada (Braga, Portugal)
2014/11/20 Drogas na adolescência IX Congresso Científico AEFFUP, “Toxicomanias e Drogas de Abuso”
FFUP (Porto, Portugal)
2014/11/06 O cérebro adolescente e o consumo de Psicofármacos Cérebro e (Dis)funções VIII Congresso Científico do NEF/ACC
NEF (Coimbra, Portugal)
2013/11 Põe.te a milhas das pastilhas” - A case-study on public health and scientific knowledge interchange Congresso Nacional de Adictologia
(Aveiro, Portugal)
2013/09/24 Acetyl-L-carnitine in acute methamphetamine exposure leads to excessive glucose uptake, impairing reference memory and deregulating mitochondrial function. Rede de Transtornos Adictivos (RTA) Meeting
RTA (Oviedo, Spain)
2013/06/01 The role of acetyl-L-carnitine in the brain glucose uptake under methamphetamine SPN Conference
SPN (Curia, Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2020/01/01 - Current Psychostimulant-induced neuroinflammation: the protective role of IL-10 (FCT Grant- SFRH/BD/144324/2019)
Supervisor of Ana Isabel Silva
MCBiology doctoral program (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018 - Current Encoding of temporal and spatial cues in drug-seeking behavior
Co-supervisor of Joana Gomes Ribeiro
LisbonBioMed doctoral program (PhD)
Instituto de Medicina Molecular, Portugal
2018 - Current Psychostimulants and neuroinflammation: finding critical players in a crosstalk between glial cells and neurons (FCT - PD/BD/135450/2017)
Supervisor of Joana Catarina Silva Bravo
GABBA doctoral program (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023 - 2023 Deciphering the glial and synaptic changes under chronic alcohol exposure using a self-administration paradigm
Supervisor of Ana Margarida Bravo Rodrigues
Neurobiologia (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2016 - 2022/02 Unveiling the cellular and molecular players involved in methamphetamine-induced neuroinflammation: focus on astrocyte-microglial crosstalk (FCT – SFRH/BD/117148/2016)
Supervisor of Teresa Correia Soares Canedo
Doctoral Program in Neurosciences (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2021 - 2021 The impact of natural cannabinoids on neuroinflammation
Supervisor of Catarina Magalhães Silva
Medicina (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021 - 2021 Psychostimulant-induced neuroinflammation: the roleo of RhoGTPases in microglia (FCT Grant- 2020.07188.B)
Supervisor
Biologia Molecular e Celular (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013 - 2021 Postdoc work - Can regulation of cytoskeleton actin dynamics prevent methamphetamine-induced dysfunction?
Supervisor of Andrea Catarina Amaro Campos Lobo
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019 - 2019 Neuron-microglia crosstalk under methamphetamine: exploring ligand-receptor pairs that may attenuate microglia reactivity
Supervisor of Inês Moreira Ribeiro
Neurobiologia (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2017 - 2019 Neuron-microglia crosstalk under methamphetamine: exploring ligand-receptor pairs that may attenuate microglia reactivity
Supervisor of Inês Ribeiro
Master in Neurobiology (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2018 - 2018 Psychostimulants and neuroinflammation: finding critical players in the crosstalk between glial cells and neurons
Supervisor
Biologia Básica e Aplicada (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015 - 2017/09 Psychostimulant abuse and neuroinflammation: a crosstalk between glial cells and neurons
Supervisor of Joana Catarina Silva Bravo
Master in Neurobiology (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2017 - 2017 Unveiling the cellular and molecular players involved in methemphetamine induced neuroinflammation: focus on astrocyte-microglial crosstalk
Supervisor
Neurociências (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2017 - 2017 Psychostimulant abuse and neuroinflammation: a crosstalk between glial cells and neurons
Supervisor
Neurobiologia (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2015 - 2017 Mechanisms of alcohol modulation of microglial function
Supervisor of Joana Fernandes Henriques
Integrated Master in Bioengineering (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016 - 2016 Exploring new possible targets in Methamphetamine exposure
Supervisor
Biologia Celular e Molecular (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2016 - 2016 Neuronal morphology regulation under chronic exposure to psychostimulant drugs: new therapeutic targets
Supervisor
Bioquímica (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2014 - 2016 Exploring new targets in metamphetamine exposure
Supervisor of Joana Alexandra Moreira Ribeiro
Master in Cellular and Molecular Biology (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2014 - 2016 Neuronal morphology regulation and new therapeutic targets under psychostimulant drugs
Supervisor of João Magalhães
Master in Biochemistry (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2010 - 2016 Postdoc work - NPwhY, cross-talk between regenerating bone and NPY
Co-supervisor
Instituto Nacional de Engenharia Biomédica, Portugal
2011 - 2015 Understanding the neuroprotective mechanisms of acetyl-L-carnitine
Supervisor of Sílvia Patrícia Morim Fernandes
Doctoral Program in Neurosciences (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2012 - 2014 The role of microglia in methamphetamine exposure
Supervisor of Teresa Correia Soares Canedo
Master in Forensic Sciences (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2010 - 2014 Acetyl-L-Carnitine Neuroprotection in Mitochondrial Dysfunction
Supervisor of Lídia Alexandra Santos Cunha
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2010 - 2014 Postdoc work - Relevance of early social adverse experiments in risk-taken behaviors and substance use in the adolescent
Supervisor of Ana Isabel Magalhães Gamito Carrilho
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011 - 2013 Caracterização de modelos in vitro para avaliação dos mecanismos moleculares envolvidos na ação da acetil-L-carnitina
Supervisor of Joana Filipa Ramos Lapa
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências e Tecnologia, Portugal
2008 - 2013 Effects of Ketamine administration in rats: mitochondrial and functional changes in brain and liver
Supervisor of Carlos Alberto da Silva Venâncio
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências Agrárias e Veterinárias, Portugal
2011 - 2011 Understanding the mecahanisms of acetyl-l-carnitine through neuroprotection after methamphetamine administration
Supervisor
Neurociências (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2008 - 2011 Postdoc work - Brain damage produced by consumption of ecstasy (MDMA) and alcohol in the adolescence and neuroprotective strategies
Co-supervisor
Universitat de València Facultat de Psicologia, Spain
2009 - 2010 Acetyl-L-Carnitine neuroprotection in a in vitro model
Supervisor of Danira Damiani
Università degli Studi di Pavia Facoltà di Medicina e Chirurgia, Italy
2005 - 2008/02 Neurotoxicity of methylenodioxymethamphetamine (MDMA; ecstasy) its main metabolites, in rat brain mitochondria in vivo
Co-supervisor of Ema Luís Alves
Universidade do Porto Faculdade de Farmácia, Portugal
2007 - 2007 Effects of hetamine administration in rats: mitochondrial and functional changes in brain and liver
Supervisor
Ciências Veterinárias (PhD)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências Agrárias e Veterinárias, Portugal

Event organisation

Event name
Type of event (Role)
Institution / Organization
2018/09 - Current Organized the first Retreat of the “Seminars on Neurobiology and Neurologic Disorders “ at I3S, Casa de Serralves, Porto. (2018 - 2018)
Meeting (Co-organisor)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/09/19 - 2023/09/19 Exposure to cannabis in the adolescent, conference taking place at the Portuguese Parliament. (2023/09/19 - 2023/09/19)
Conference (Co-organisor)
GAT - Grupo de Activistas de tratamentos, Portugal
2023/07 - 2023/07 ISN Douro Myelin meeting (2023/07 - 2023/07)
Conference (Co-organisor)
Sociedade Portuguesa de Neurociências, Portugal
2023/05 - 2023/05 FENS regional meeting (2023/05 - 2023/05)
Conference (Member of the Organising Committee)
FENS - Federation of European Neuroscience Societies, Belgium
2021/09 - 2023/05 FENS 2023 Regional Meeting (2021/09 - 2023/05)
Conference (Co-organisor)
Sociedade Portuguesa de Neurociências, Portugal
2019/03/16 - 2019/03/21 Brain Awareness Week (2019/03/18 - 2019/03/21)
Exhibition (Co-organisor)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018 - 2019 Integrates the Local Organizing Committee of XIV European Meeting on Glial Cells in Health and Disease, Porto, Portugal (2019/06 - 2019/06)
Conference (Member of the Organising Committee)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2016 - 2019 Co-organized the first three rounds of “Seminars on Neurobiology and Neurologic Disorders “ at I3S, Porto. (2016)
Seminar (Co-organisor)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2015 - 2015 Co-organized the XIV Meeting of the PORTUGUESE SOCIETY FOR NEUROSCIENCES 4-5 JUNE, PÓVOA DE VARZIM, Portugal (2015 - 2015)
Conference (Member of the Organising Committee)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2013/04 - 2013/04 Organized the Think Tank “Mexer no cérebro”, April , EDP, Porto. (2013/04 - 2013/04)
Round table (Co-organisor)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2012/06 - 2012/06 Organized the workshop “Neurobiology of addiction”, June, ICBAS, Porto (2012/06 - 2012/06)
Workshop (Co-organisor)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011/05 - 2011/05 Organized the workshop “The other cells of the nervous system”, May, ESTSP, Porto. (2011/05 - 2011/05)
Workshop (Co-organisor)
Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2009 - 2011 Coordinated the Brain Awareness Week activities at IBMC (supported by DANA Alliance and the Portuguese Neuroscience Society). (2009 - 2011)
Other (Co-organisor)
Dana Foundation, United States
2006/06 - 2006/06 Organized the “II Symposium on the Neurobiology of Drugs of Abuse”, June, IBMC, Porto (2006 - 2006)
Symposium (Co-organisor)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2005/05 - 2005/05 Organized the “I Symposium on the Neurobiology of Drugs of Abuse”, May, IBMC, Porto. (2005/05 - 2005/05)
Symposium (Co-organisor)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2009 - 2010 Collaborated with the project “Exuberances of the Black Box”, an exhibition planned to celebrate the centenary of Darwin’s death through its book “The Expression of the Emotions in Man and Animals". Museu Nacional Soares dos Reis, Porto.
Exhibition
Exuberances of the Black Box
Museu Nacional Soares dos Reis, Portugal
2008/05 - 2008/05 Collaborated with the association “Ilhas em Movimento” presenting informative sessions in all high schools at Ponta Delgada, São Miguel, Azores.
Workshop
Põe.te amilhas das pastilhas
Governo dos Açores, Portugal

Association member

Society Organization name Role
2020/06/17 - Current Instituto de Biologia Molecular e Celular Associated Member

Committee member

Activity description
Role
Institution / Organization
2022/01 - Current European Brain Council -task force for animal experimentation
Member
2021/12 - Current Portuguese Network Glia - board member
Member
2021/01 - Current Member of CARE (Committee on Animals in Research) at FENS, as the portuguese representative
Member
Federation of European Neuroscience Societies, Belgium
2015 - Current Member of Scientific Committee of the Instituto de Investigação e inovação em Saúde (i3S)
Member
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2010/01/01 - Current Founder Member of the Ethical Commission for Animal Experimentation at IBMC representing the Neuroscience Research Line
Member
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2010 - Current Member of the Ethical Commission for Animal Experimentation at IBMC representing the Neuroscience Research Line (since 2010- present)
Member
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2016/01/01 - 2022/01 Founder member of the ORBEA body at I3S, representing the Neurobiology and Neurologic Disorders program.
Member
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017/11/01 - 2021/10/30 Executive committee IBMC, represents the IBMC investigators.
Member
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Conference scientific committee

Conference name Conference host
2019 - Current XVI Meeting of the Portuguese Society for Neuroscience Portuguese Society for Neuroscience (SPN)
2024/10 - 2024/10 Lisbon Addictions conference 2024 SICAD/ICAD
2023/07 - 2023/07 ISN Douro Myelin meeting SPN
2023/05 - 2023/05 FESN Regional meeting SPN
2018 - 2019/07 XIV European Meeting on Glial Cells in Health and Disease Network Glia
2018/05/30 - 2019/05/30 XVI Meeting of the Portuguese Society for Neuroscience iMM
2015 - 2016 International Conference Projecto Homem Projecto Homem
2013/05 - 2015/06 XIV Meeting of the Portuguese Society for Neuroscience SPN

Consulting

Activity description Institution / Organization
2018 - Current Invited by the Health Commission at the Portuguese Parliament to contribute as Expert in the field of Drug Abuse to the scientific and politic discussion regarding the use o Medical Cannabis (Spring 2018) Assembleia da República, Portugal
2016 - Current Nominated National Stakeholder for ERANID (European Research Area Network on Illicit Drugs) to represent the Portuguese delegation Serviço de Intervenção nos Comportamentos Aditivos e nas Dependências IP, Portugal
2015/05/08 - 2015/05/10 Represented FCT in a Working Group on Research Infrastructures (WG RIs) to explore the opportunity for national organisations to engage with networks of research infrastructures as a tool to promote cooperation between national infrastructure strategies and/or between national and EU infrastructure strategies. FCT - Fundação para a Ciência e Tecnologia, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2018/01 - Current MCBiology doctoral program, I3S, University of Porto Neurosciences course - Neurotransmission and higher functions PhD level (Doutoramento) Universidade do Porto, Portugal
2015 - Current Short course on “Neurobiology of Addiction” to health professionals in the field of addiction, invited by Administração Regional de Saúde do Norte (ARS Norte, Porto) – 24 hours. (Outros) Administração Regional de Saúde do Norte IP, Portugal
2015 - Current Master course in Neurbiology, FMUP, University of Porto. Coordinates the Neurotoxicology module (13 h). Master in Neurobiology (Mestrado) Universidade do Porto Faculdade de Medicina, Portugal
2014 - Current Short course on “Neurobiology of Addiction” to health professionals in the field of addiction, invited by Administração Regional de Saúde do Norte (ARS Norte, Porto) – 24 hours. (Outros) Administração Regional de Saúde do Norte IP, Portugal
2013 - Current Collaborates in the Educational Program of both the Male a Female prisons in Custoias, delivering sessions on "The Addicted brain"¿. (Outros)
2012/06/01 - Current Core Member of the Neuroscience Doctoral Program, Medical School, University of Porto (FMUP) – Coordinates the Neurotoxicology course (13 h) PDN - Neurotoxicologia (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2012 - Current GABBA Doctoral Program, University of Porto (ICBAS) – Coordinates the Neurobiology of Addiction course Neurobiology of Addiction (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012 - Current Master course in “Risk and Environmental Health” (12h), ESS.PP Coordinator of the module “Intervention in adolescent risk behaviour”, (Previously known as master course of “Environment, Hygiene and high-school security” , ESS.PP) Risk and Environmental Health (Mestrado) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2010 - Current Collaborates in Master course in “Psychology of the Deviant Behaviour” invited by Fernando Barbosa and João Marques Teixeira (2h), Faculty of Psychology, University of Porto (Mestrado) Universidade do Porto Faculdade de Psicologia e de Ciências da Educação, Portugal
2009/10/01 - Current Master in Occupational Health, Mental Health Option: Neuroinflammation and disease (4h); Addiction and Substance abuse (4h); Smart drugs and Neuroenhancement (4h). Terapia Ocupacional - Opção em Saúde Mental (Mental Health) (Mestrado) Instituto Politécnico do Porto Escola Superior de Saúde, Portugal
2018/05 - 2018/05 Short course on “Neurobiology of Addiction” to health professionals in the field of addiction, invited by Administração Regional de Saúde do Norte (ARS Centro, Coimbra) – 8 hours. (Outros) Administração Regional de Saúde do Centro IP, Portugal
2007 - 2007 “Neurobiology of drug abuse” (9h), Master course “Psychology of Rehabilitation”, Faculty of Phycology, University of Porto (under a protocol with ESS.PP) (Mestrado) Universidade do Porto Faculdade de Psicologia e de Ciências da Educação, Portugal

Evaluation committee

Activity description
Role
Institution / Organization Funding entity
2021/11 - Current Evaluator for La Caixa" Foundation (Spain), Junior Group Leader positions
Evaluator
Obra Social La Caixa, Spain
2020/02 - Current Evaluator for “La Caixa" Foundation (Spain), Grants and Awards for PhD Grants
Evaluator
Obra Social La Caixa, Spain Obra Social La Caixa
2018/12 - 2021/07 Evaluator for “La Caixa" Foundation (Spain), Grants and Awards to Junior Group Leaders
Evaluator
Obra Social La Caixa, Spain Obra Social La Caixa
2020/05 - 2020/05 Evaluation of Research Grants
Evaluator
Poland National Science Centre, Poland Poland National Science Centre
2017/06 - 2017/06 Mostra Nacional de Ciência, Ciência Viva for junior students (Coordinator of the Medical Sciences panel).
Evaluator
Ciência Viva, Portugal Ciência Viva
2015 - 2015 GAI research projects (University of Coimbra) evaluation pannel
Evaluator
Universidade de Coimbra Faculdade de Medicina, Portugal Universidade de Coimbra Faculdade de Medicina

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2019/02/18 How to measure happiness in brain activity. DN Life
2018 The risks of smoking cannabinoids Sol
2018 Fact check. Cannabis for medical use Observador
2017 Smart shops and synthetic cannabinoids. Visão
2016 Academic doping. Obervador
2015 Article discussing the use of smart drugs. Visão

Interview (tv / radio show)

Program Topic
2019 - Current Olhe que não (Maybe not...) Discussion on cannabis legalization
2016/11 - Current 90 Seconds of Science (http://www.90segundosdeciencia.pt/) Teresa Summavielle research aims, episode #2
2014 - Current Participation in TV live debate regarding the use of cognitive enhancers, Prós e Contras, February, RTP, Lisboa. Smart drugs
2013 - Current Participation in TV live debate on the Smart shops problem, Prós e Contras, RTP, February, Lisboa Smart shops
2021/05/04 - 2021/05/04 É ou não é? Research precarity

Other jury / evaluation

Activity description Institution / Organization
2010 - Current Participation in Master Committees: Integrated 26 Master Evaluation Committees, 20 of them as external examiner.
2005 - Current Integrated 20 PhD Evaluation Committees, 12 of them as external/main examiner.
2004 - Current AD HOC Reviewer for Scientific Journals: Brain Behavior and Immunity, Neuropharmacology; Scientific Reports; J Neuroinflammation; Eur Neuropsychopharmacol; Pharmacological Reports; Neuroscience; BJP; Toxicol Letters; Neurobiology of Disease; Acta Neuropathologica; Pharmacology, Biochemistry and Behaviour; Synapse; Journal of Neurotransmission; Psychopharmacology; Metabolic Brain Disease; Drug and Alcohol Dependence; Journal of Psychopharmacology; Clinical Case Reports; Neurotoxicology; Clinical and Experimental Pharmacology; Neurotherapeutics; Cells
Distinctions

Award

2022 CEECindividual
FCT - Fundação para a Ciência e Tecnologia, Portugal
2019 Best paper
Sociedade Portuguesa de Imunologia, Portugal
2017 Honorable Mention, 8th Edition of the Manuel António da Mota Awards, for a collaborative Social Project between Santa Casa da Misericórdia, FMUP and I3S (target population – problematic adolescent drug users).
Fundação Manuel António da Mota, Portugal
2016 Mulheres na Ciencia
Ciência Viva, Portugal
2015 Mulheres na Ciencia
Ciência Viva, Portugal
2013 Investigador FCT - Development Level
Fundação para a Ciência e a Tecnologia, Portugal
2013 Investigador FCT (Development Level) –IF (IF/00875/2012)
FCT - Fundação para a Ciência e Tecnologia, Portugal
2007 Travel award to SFN
National Institute on Drug Abuse Medicinal Chemistry Section, United States
2007 FCT postdoctoral grant (SFRH/BPD/20997/2004), second trienium
FCT - Fundação para a Ciência e Tecnologia, Portugal
2004 FCT postdoctoral grant (SFRH/BPD/20997/2004)
FCT - Fundação para a Ciência e Tecnologia, Portugal
1998 FCT PhD grant, reference PRAXIS XXI/BD/14742/97
FCT - Fundação para a Ciência e Tecnologia, Portugal
1997 Student Travel Award

Other distinction

2020 Editorial note in Science: Leslie K. Ferrarelli. Tipsy microglia binge on synapses. Science 25 Sep 2020: Vol. 369, Issue 6511, pp. 1579 https://science.sciencemag.org/content/369/6511/twis.full; Altmetric score 312 - top 5% of all research outputs score
2017 I3S Ambassador
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal