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Ana Filipa Sousa Pestana Mourão concluiu o Doutoramento em Medicina pela Faculdade de Ciências Médicas, Universidade Nova de Lisboa em 2016. É licenciada em Medicina pela Faculdade de Medicina, Universidade de Lisboa desde 2002. Concluiu o internato complementar de Reumatologia no Hospital de Egas Moniz em 2010. É Professora Auxiliar Convidada na Faculdade de Ciências Médicas, Universidade Nova de Lisboa desde 2016. É Assistente de Reumatologia no Hospital de Egas Moniz desde 2010. É coordenadora da consulta de Reumatologia Pediátrica no Hospital de Egas Moniz desde 2017. É coordenadora da consulta de Reumatologia Pediátrica no Hospital de São Francisco Xavier desde 2015. É membro da equipa de investigação da unidade de Doenças Reumáticas no Centro de Estudos de Doenças Crónicas (CEDOC), Universidade Nova de Lisboa desde 2009. Participa em diversos projectos de investigação com colaborações nacionais e internacionais desde 2005. É co-autora de vários prémios com mérito científico reconhecido, incluindo o Grande Prémio Bial de Medicina 2015. Publicou mais de 60 artigos em revistas especializadas, 4 capítulos de livros e é primeira autora e/ ou co-autora de mais de 200 comunicações orais e posters em encontros científicos nacionais e internacionais.
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Identification

Personal identification

Full name
Ana Filipa Sousa Pestana Mourão

Citation names

  • Mourão, Ana F.
  • Mourão AF

Author identifiers

Ciência ID
C415-49D5-3029

Email addresses

  • afilipamourao@gmail.com (Professional)

Telephones

Mobile phone
  • 965829733 (Personal)

Addresses

  • Hospital Egas Moniz - Centro Hospitalar de Lisboa Ocidental, EPE, Lisboa. Rua da Junqueira, 126, 1349-019, Lisboa, Lisboa, Portugal (Professional)

Knowledge fields

  • Medical and Health Sciences - Clinical Medicine - Rheumatology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
French Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
Spanish; Castilian Advanced (C1) Advanced (C1) Intermediate (B1) Advanced (C1)
English Advanced (C1) Advanced (C1) Intermediate (B1) Advanced (C1)
Education
Degree Classification
2016
Concluded
 Medicina (Doutoramento)
Major in Especialidade de Reumatologia
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
"Factores de susceptibilidade e Prognóstico em doentes Portugueses com artrite idiopática juvenil" (THESIS/DISSERTATION)
 Aprovação com distinção e louvor
2002
Concluded
 Medicina (Licenciatura)
Universidade de Lisboa Faculdade de Medicina, Portugal
 16
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2016 - Current Invited Assistant Professor (University Teacher) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2009 - 2016 Invited Assistant (University Teacher) Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Others

Category
Host institution 		Employer
2017 - Current Coordenadora da Consulta de Reumatologia Pediátrica Hospital de Egas Moniz, Portugal
2015 - Current Coordenadora da Consulta de Reumatologia Pediátrica Hospital de São Francisco Xavier, Portugal
2010 - Current Assistente de Reumatologia Hospital de Egas Moniz, Portugal
2009 - Current Investigadora na unidade de Doenças Reumáticas Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
2010 - 2016 Estudante de Doutoramento Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2003 - 2016 Investigadora na Unidade de Investigação em Reumatologia Instituto de Medicina Molecular João Lobo Antunes, Portugal
2005 - 2010 Internato Complementar de Reumatologia Hospital de Egas Moniz, Portugal
2002 - 2004 Internato Geral Hospital S. José, Portugal
1996 - 2002 Estudante de Medicina Universidade de Lisboa Faculdade de Medicina, Portugal
Projects

Other

Designation Funders
2010 - 2016 Factores de susceptibilidade, prognóstico e farmacogenéticos em doentes Portugueses com Artrite Idiopática Juvenil
N/A
Other
2008 - 2008 Mulher Portuguesa pós-menopausica - Estudo da relação entre osteoporose, aterosclerose e litíase renal – potenciais implicações clínicas futuras
N/A
Researcher
2007 - 2007 Monócitos CD14+CD16+ na artrite
N/A
Researcher
2006 - 2006 Espondilite Anquilosante: caracterização genómica e funcional dos genes candidatos e a sua repercussão na prática clínica
N/A
Researcher
2005 - 2005 Gene do factor de necrose tumoral alfa e artrite reumatóide – prognóstico e farmacogenética
N/A
Researcher
2005 - 2005 Papel do polimorfismo na posição -308 do gene do factor de necrose tumoral alfa na susceptibilidade e padrão de actividade da artrite idiopática juvenil
N/A
Other
Outputs

Publications

Journal article
  1. Marona, Jose; Sepriano, Alexandre; Rodrigues-Manica, Santiago; Pimentel-Santos, Fernando; Mourão, Ana Filipa; Gouveia, Nélia; Branco, Jaime Cunha; et al. "Eligibility criteria for biologic disease-modifying antirheumatic drugs in axial spondyloarthritis: going beyond BASDAI". RMD Open 6 1 (2020): e001145. http://dx.doi.org/10.1136/rmdopen-2019-001145.
    10.1136/rmdopen-2019-001145
  2. Mourão AF. "Benign transient hyperphosphatasemia in Juvenile Idiopathic Arthritis: a case report". Acta Reumatol Port 44 4 (2019): 317-319.
  3. Mourão AF. "Portuguese recommendations for the prevention, diagnosis and management of primary osteoporosis - 2018 update". Acta Reumatol Port 43 1 (2018): 10-31.
  4. Gonçalves, Maria J.; Mourão, Ana F.; Martinho, António; Simões, Olívia; Melo-Gomes, José; Salgado, Manuel; Estanqueiro, Paula; et al. "Genetic Screening of Mutations Associated with Fabry Disease in a Nationwide Cohort of Juvenile Idiopathic Arthritis Patients". Frontiers in Medicine 4 (2017): http://dx.doi.org/10.3389/fmed.2017.00012.
    10.3389/fmed.2017.00012
  5. Mourão AF. "Reuma.pt contribution to the knowledge of immune-mediated systemic rheumatic diseases". Acta Reumatol Port (2017):
  6. Mourão AF. "The Portuguese Society of Rheumatology position paper on the use of biosimilars - 2017 update". Acta Reumatol Port (2017):
  7. Mourão AF. "Acta Reumatológica Portuguesa: perspectives in 2017". Acta Reumatol Port (2017):
  8. Mourão AF. "Portuguese recommendations for the use of methotrexate in rheumatic diseases - 2016 update". (2017):
  9. Mourão AF. "Real-life effectiveness of Golimumab in biologic-naïve patients with rheumatoid arthritis - data from the Rheumatic Diseases Portuguese Register (Reuma.pt)". (2017):
  10. Oliveira-Ramos, Filipa; Eusébio, Mónica; M Martins, Fernando; Mourão, Ana Filipa; Furtado, Carolina; Campanilho-Marques, Raquel; Cordeiro, Inês; et al. "Juvenile idiopathic arthritis in adulthood: fulfilment of classification criteria for adult rheumatic diseases, long-term outcomes and predictors of inactive disease, functional status and damage". RMD Open 2 2 (2016): e000304. http://dx.doi.org/10.1136/rmdopen-2016-000304.
    10.1136/rmdopen-2016-000304
  11. Araujo, Galber R.; Fujimura, Patricia T.; Vaz, Emília R.; Silva, Tamiris A.; Rodovalho, Vinícius R.; Britto-Madurro, Ana Graci; Madurro, João M.; et al. "A novel reactive epitope-based antigen targeted by serum autoantibodies in oligoarticular and polyarticular juvenile idiopathic arthritis and development of an electrochemical biosensor". Immunobiology 221 5 (2016): 634-640. http://dx.doi.org/10.1016/j.imbio.2016.01.006.
    10.1016/j.imbio.2016.01.006
  12. Branco, Jaime C; Rodrigues, Ana M; Gouveia, Nélia; Eusébio, Mónica; Ramiro, Sofia; Machado, Pedro M; da Costa, Leonor Pereira; et al. "Prevalence of rheumatic and musculoskeletal diseases and their impact on health-related quality of life, physical function and mental health in Portugal: results from EpiReumaPt– a national health survey". RMD Open 2 1 (2016): e000166. http://dx.doi.org/10.1136/rmdopen-2015-000166.
    10.1136/rmdopen-2015-000166
  13. Mourão AF. "2016 update of the Portuguese recommendations for the use of biological therapies in children and adolescents with Juvenile Idiopathic Arthritis". (2016):
  14. Mourão, Ana F.; Santos, Maria J.; Melo Gomes, José A.; Martins, Fernando M.; Mendonça, Sílvia C.; Oliveira Ramos, Filipa; Fernandes, Susana; et al. "Effectiveness and long-term retention of anti-tumour necrosis factor treatment in juvenile and adult patients with juvenile idiopathic arthritis: data from Reuma.pt". Rheumatology 55 4 (2015): 697-703. http://dx.doi.org/10.1093/rheumatology/kev398.
    10.1093/rheumatology/kev398
  15. Araujo, Galber R.; Fonseca, João E.; Fujimura, Patricia T.; Cunha-Junior, Jair P.; Silva, Carlos H.M.; Mourão, Ana F.; Canhão, Helena; et al. "Anti-type II collagen antibodies detection and avidity in patients with oligoarticular and polyarticular forms of juvenile idiopathic arthritis". Immunology Letters 165 1 (2015): 20-25. http://dx.doi.org/10.1016/j.imlet.2015.03.006.
    10.1016/j.imlet.2015.03.006
  16. Mourão, Ana Filipa; Santos, Maria José; Mendonça, Sílvia; Oliveira-Ramos, Filipa; Salgado, Manuel; Estanqueiro, Paula; Melo-Gomes, José; et al. "Genetic Predictors of Poor Prognosis in Portuguese Patients with Juvenile Idiopathic Arthritis: Data from Reuma.pt". Journal of Immunology Research 2015 (2015): 1-6. http://dx.doi.org/10.1155/2015/706515.
    10.1155/2015/706515
  17. Mourão AF. "EpiReumaPt: how to perform a national population based study - a practical guide". (2015):
  18. Laires, P.A.; Canhão, H.; Gouveia, M.; Rodrigues, A.; Gouveia, N.; Branco, J.. "EpiReumaPt- the study of rheumatic and musculoskeletal diseases in Portugal: a detailed view of the methodology". (2015):
  19. Mourão, Ana F.; Santos, Maria J.; Melo-Gomes, José; Martins, Fernando M.; Costa, José A.; Ramos, Filipa; Brito, Iva; et al. "Using the Juvenile Arthritis Disease Activity Score Based on Erythrocyte Sedimentation Rate or C-Reactive Protein Level: Results From the Portuguese Register". Arthritis Care & Research 66 4 (2014): 585-591. http://dx.doi.org/10.1002/acr.22215.
    10.1002/acr.22215
  20. Mourão AF. "Portuguese recommendations for the diagnosis and management of gout". (2014):
  21. Mourão AF. "Phlyctenular keratoconjunctivitis - an atypically severe case treated with systemic biologic immunosuppressive therapy". (2014):
  22. Pimentel-Santos, F. M.; Matos, M.; Ligeiro, D.; Mourão, A. F.; Ribeiro, C.; Costa, J.; Santos, H.; et al. "HLA alleles and HLA-B27 haplotypes associated with susceptibility and severity of ankylosing spondylitis in a Portuguese population". Tissue Antigens 82 6 (2013): 374-379. http://dx.doi.org/10.1111/tan.12238.
    10.1111/tan.12238
  23. Moura, Rita A.; Canhão, Helena; Polido-Pereira, Joaquim; Rodrigues, Ana M.; Navalho, Márcio; Mourão, Ana F.; Resende, Catarina; et al. "BAFF and TACI Gene Expression Are Increased in Patients with Untreated Very Early Rheumatoid Arthritis". The Journal of Rheumatology 40 8 (2013): 1293-1302. http://dx.doi.org/10.3899/jrheum.121110.
    10.3899/jrheum.121110
  24. Canhao, H.; Rodrigues, A. M.; Mourao, A. F.; Martins, F.; Santos, M. J.; Canas-Silva, J.; Polido-Pereira, J.; et al. "Comparative effectiveness and predictors of response to tumour necrosis factor inhibitor therapies in rheumatoid arthritis". Rheumatology 51 11 (2012): 2020-2026. http://dx.doi.org/10.1093/rheumatology/kes184.
    10.1093/rheumatology/kes184
  25. Mourão AF. "[Portuguese recommendations for pain management by pharmocotherapy in inflammatory arthritis]". (2012):
  26. Mourão AF. "Portuguese recommendations for the use of biological therapies in children and adolescents with juvenile idiopathic arthritis--December 2011 update". (2012):
  27. Mourão AF. "CoReumaPt protocol: the Portuguese cohort of rheumatic diseases". (2012):
  28. Mourão AF. "Caspase-1 is active since the early phase of rheumatoid arthritis". (2012):
  29. PIMENTEL-SANTOS, FERNANDO MANUEL; LIGEIRO, DARIO; MATOS, MAFALDA; MOURÃO, ANA FILIPA; VIEIRA de SOUSA, ELSA; PINTO, PATRICIA; RIBEIRO, ANA; et al. "ANKH and Susceptibility to and Severity of Ankylosing Spondylitis". The Journal of Rheumatology 39 1 (2011): 131-134. http://dx.doi.org/10.3899/jrheum.110681.
    10.3899/jrheum.110681
  30. Pimentel-Santos, Fernando M.; Mourão, Ana Filipa; Ribeiro, Célia; Costa, José; Santos, Helena; Barcelos, Anabela; Pinto, Patricia; et al. "Spectrum of ankylosing spondylitis in Portugal. Development of BASDAI, BASFI, BASMI and mSASSS reference centile charts". Clinical Rheumatology 31 3 (2011): 447-454. http://dx.doi.org/10.1007/s10067-011-1854-7.
    10.1007/s10067-011-1854-7
  31. Pimentel-Santos, Fernando M; Ligeiro, Dário; Matos, Mafalda; Mourão, Ana F; Costa, José; Santos, Helena; Barcelos, Anabela; et al. "Whole blood transcriptional profiling in ankylosing spondylitis identifies novel candidate genes that might contribute to the inflammatory and tissue-destructive disease aspects". Arthritis Research & Therapy 13 2 (2011): http://dx.doi.org/10.1186/ar3309.
    10.1186/ar3309
  32. Mourão AF. "[Practical guide for the use of biological agents in rheumatoid arthritis - December 2011 update]". (2011):
  33. Mourão AF. "Portuguese guidelines for the use of biological agents in rheumatoid arthritis - October 2011 update". (2011):
  34. Mourão AF. "Markers of progression to rheumatoid arthritis: discriminative value of the new ACR/EULAR rheumatoid arthritis criteria in a Portuguese population with early polyarthritis". (2011):
  35. Mourão, Ana Filipa; Blyth, Fiona M.; Branco, Jaime C.. "Generalised musculoskeletal pain syndromes". Best Practice & Research Clinical Rheumatology 24 6 (2010): 829-840. http://dx.doi.org/10.1016/j.berh.2010.10.005.
    10.1016/j.berh.2010.10.005
  36. Moura, R. A.; Cascao, R.; Perpetuo, I.; Canhao, H.; Vieira-Sousa, E.; Mourao, A. F.; Rodrigues, A. M.; et al. "Cytokine pattern in very early rheumatoid arthritis favours B-cell activation and survival". Rheumatology 50 2 (2010): 278-282. http://dx.doi.org/10.1093/rheumatology/keq338.
    10.1093/rheumatology/keq338
  37. Cascão, Rita; Moura, Rita A; Perpétuo, Inês; Canhão, Helena; Vieira-Sousa, Elsa; Mourão, Ana F; Rodrigues, Ana M; et al. "Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritis". Arthritis Research & Therapy 12 5 (2010): http://dx.doi.org/10.1186/ar3168.
    10.1186/ar3168
  38. Jonsdottir, T.; Gunnarsson, I.; Mourao, A. F.; Lu, T. Y.; van Vollenhoven, R. F.; Isenberg, D.. "Clinical improvements in proliferative vs membranous lupus nephritis following B-cell depletion: pooled data from two cohorts". Rheumatology 49 8 (2010): 1502-1504. http://dx.doi.org/10.1093/rheumatology/keq055.
    10.1093/rheumatology/keq055
  39. Moura, R. A.; Weinmann, P.; Pereira, P. A.; Caetano-Lopes, J.; Canhao, H.; Sousa, E.; Mourao, A. F.; et al. "Alterations on peripheral blood B-cell subpopulations in very early arthritis patients". Rheumatology 49 6 (2010): 1082-1092. http://dx.doi.org/10.1093/rheumatology/keq029.
    10.1093/rheumatology/keq029
  40. Bogas, Mónica; Machado, Pedro; Mourão, Ana Filipa; Costa, Lúcia; Santos, Maria José; Fonseca, João Eurico; Silva, José António P.; Canhão, Helena. "Methotrexate treatment in rheumatoid arthritis: management in clinical remission, common infection and tuberculosis. Results from a systematic literature review". Clinical Rheumatology 29 6 (2010): 629-635. http://dx.doi.org/10.1007/s10067-010-1380-z.
    10.1007/s10067-010-1380-z
  41. Mourão AF. "[Portuguese recommendations on "How to diagnose, monitor, and treat undifferentiated peripheral arthritis": systematic review of the literature and the experts' opinion]". (2010):
  42. Mourão AF. "From a neutrophilic synovial tissue infiltrate to a challenging case of rheumatoid arthritis". (2010):
  43. Mourão AF. "Exacerbation of psoriatic skin lesions in patients with psoriatic arthritis receiving anti-tumour necrosis factor-alpha therapy: description of 3 cases and review of the literature". (2010):
  44. Mourão AF. "Portuguese guidelines for the use of biological agents in rheumatoid arthritis - March 2010 update". (2010):
  45. Mourão, AF; Amaral, M.; Caetano-Lopes, J.; Isenberg, D.. "An analysis of joint replacement in patients with systemic lupus erythematosus". Lupus 18 14 (2009): 1298-1302. http://dx.doi.org/10.1177/0961203309345795.
    10.1177/0961203309345795
  46. Sousa, Elsa; Caetano-Lopes, Joana; Pinto, Patrícia; Pimentel, Fernando; Teles, José; Canhão, Helena; Rodrigues, Ana; et al. "Ankylosing Spondylitis Susceptibility and Severity-Contribution of TNF Gene Promoter Polymorphisms at Positions -238 and -308". Annals of the New York Academy of Sciences 1173 1 (2009): 581-588. http://dx.doi.org/10.1111/j.1749-6632.2009.04758.x.
    10.1111/j.1749-6632.2009.04758.x
  47. MOURÃO, ANA FILIPA; CAETANO-LOPES, JOANA; COSTA, PAULA; CANHÃO, HELENA; SANTOS, MARIA JOSÉ; PINTO, PATRÍCIA; BRITO, IVA; et al. "Tumor Necrosis Factor-a -308 Genotypes Influence Inflammatory Activity and TNF-a Serum Concentrations in Children with Juvenile Idiopathic Arthritis". The Journal of Rheumatology 36 4 (2009): 837-842. http://dx.doi.org/10.3899/jrheum.080615.
    10.3899/jrheum.080615
  48. Mourão AF. "Association of IL23R and ERAP1 genes with ankylosing spondylitis in a Portuguese population". (2009):
  49. Mourão AF. "[Juvenile dermatomyositis associated with anasarca - a clinical case]". (2009):
  50. Mourão AF. "[Foreign body reaction to palm leaf]". (2009):
  51. Mourão AF. "[Portuguese recommendations for the use of methotrexate in the treatment of rheumatoid arthritis]". (2009):
  52. Mourão AF. "[Eosinophilic fasciitis and aplastic anemia]". (2009):
  53. Mourão AF. "[Is the response to anti-TNFalpha treatment influenced by the presence of IgM rheumatoid factor, in Rheumatoid Arthritis patients?]". (2008):
  54. Mourão AF. "[Cystic Rheumatoid Arthritis--case report]". (2007):
  55. Mourão AF. "[Fetal safety profile of drugs used in the treatment of inflammatory rheumatic diseases]". (2007):
  56. Mourão AF. "[Genetic basis of ankylosing spondylitis]". (2007):
  57. Fonseca, João; Cavaleiro, João; Teles, José; Sousa, Elsa; Andreozzi, Valeska L; Antunes, Marília; Amaral-Turkman, Maria A; et al. "Contribution for new genetic markers of rheumatoid arthritis activity and severity: sequencing of the tumor necrosis factor-alpha gene promoter". Arthritis Research & Therapy 9 2 (2007): R37. http://dx.doi.org/10.1186/ar2173.
    10.1186/ar2173
  58. Mourão AF. "[Stroke as the dramatic presentation of infectious endocarditis: the importance of the clinical history]". (2006):
  59. Fonseca, J E. "Polymorphism at position -308 of the tumour necrosis factor   gene and rheumatoid arthritis pharmacogenetics". Annals of the Rheumatic Diseases 64 5 (2005): 793-794. http://dx.doi.org/10.1136/ard.2004.028167.
    10.1136/ard.2004.028167
  60. Mourão AF. "Nutritional risk and status assessment in surgical patients: a challenge amidst plenty". (2004):
Activities

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2021/02/18 Caracterização da utilização de instrumentos autoreportados na fisioterapia músculo-esquelética em Portugal
President of the jury
 Ruben José Frazão Santos (Master)
Instituto Politécnico de Setúbal, Portugal
2021/02/18 Programa SPLIT: Resultados e fatores de prognóstico para os resultados de sucesso em utentes com lombalgia
President of the jury
 Cláudia da Conceição Teixeira Silva (Master)
Instituto Politécnico de Setúbal, Portugal
2021/02/18 Fatores de Prognostico para a dor persistente e incapacitante em utentes com Lombalgia que recorrem aos cuidados de saúde primários
President of the jury
 Daniela Ferreira Gomes da Silva Correia (Master)
Instituto Politécnico de Setúbal, Portugal
2019/02/20 Coupling of atherosclerosis progression and bone disturbances in inflammatory rheumatic diseases
(Thesis) Arguer
 Diana Almeida Carmona Fernandes (PhD)
Universidade de Lisboa Faculdade de Medicina, Portugal
2015 The role of inflammation in the coupling of atherosclerosis and osteoporosis Natacha Leonardo (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal

Other jury / evaluation

Activity description Institution / Organization
2017 - 2017 Membro do Júri do Prémio Egdar Stene 2017, da Liga Europeia Contra as Doenças Reumáticas (EULAR)
2017 - 2017 Presidente do Júri da Bolsa Sociedade Portuguesa de Reumatologia/ Celgene com o tema "Avaliação Multidisciplinar na Artrite Psoriatica"
Distinctions

Award

2016 Grande Prémio BIAL de Medicina 2015 (co-autoria)
2015 Prémio “Grunenthal Dor 2014” (co-autoria)
2010 Prémio Banco Espírito Santo 2010
2008 Prémio BIAL de Medicina Clínica 2008 (co-autoria)

Other distinction

2012 Bolsa do Fundo de Apoio à Investigação da Sociedade Portuguesa de Reumatologia
2010 Bolsa Abbvie (110000€) atribuída ao projeto “Fatores de susceptibilidade e prognóstico em doentes portugueses com artrite idiopática juvenil”
2009 Bolsa do Programa Doutoral do Interno Doutorando da Fundação para a Ciência e Tecnologia
Fundação para a Ciência e a Tecnologia, Portugal
2005 Prémio de Investigação Clínica da Fundação AstraZeneca