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MARGARIDA CASAL, Full Professor at the University of Minho. Expertise: Molecular Biotechnology, Structural Biology and Synthetic Protein Biotechnology. Currently my main scientific interests are dedicated to: i) Uncovering novel Plasma Membrane Transporters. By using a variety of biological materials, covering bacteria, yeasts or human cells, we have been able to unlock the structure and function of carboxylic acid permeases. We want to understand how they work and selectively transport platform chemical compounds eg. lactate, succinate, citrate. ii) Multifunctional protein-based materials for advanced applications. Our team gathers the expertise to design, produce, characterize and develop applications for natural and recombinant biopolymers with the ultimate goal of substituting, in the future, petro-based materials (plastics). My research is aligned with an agenda that intends to contrubute to an environmental sustainable Society! I have authored 12 patents, 9 book chapters and 157 WoS indexed publications (February, 2026). I have assured the supervision of more than 20 pos-Doc, 25 PhD (1 ongoing), 23 Master (2 ongoing) students and 45 project fellows. I was invited as a speaker to 50 lectures in national and international symposia. I am Referee of 22 Journals indexed in ISI and Scopus. I have evaluated research projects submitted to funding agencies from Austria, Czech Republic and Belgium as well as from FCT, FP7, IFS and ESF. I had severel positions at UMinho, namely Director of the Department of Biology, member of the General Council, Dean of the School of Sciences and Vice Rector for Education and Head of the Center of Molecular and Environmental Biology (2013-16) evaluated with Excellent. Currently I am the coordinator of the PhD program in Applied and Environmental Microbiology enrolling 30 PhD students. I was president of the organizing committee of ten national and two international conferences and President of the Portuguese Society of Genetics. I have participated in more than 50 research projects funded by national or international agencies, as well as private companies. As PI, in the last 6y I raised about 5 ME of funding. In summary, my contribution to Science, after working more than 30 years as a Biologist, my scientific interests have always focused on the structural-functional analysis of proteins with the aim of understanding the molecular characteristics that allow proteins to carry out work in the cell.
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Identification

Personal identification

Full name
Margarida Paula Pedra Amorim Casal

Citation names

  • Casal, Margarida
  • Margarida Paula Pedra Amorim Casal

Author identifiers

Ciência ID
C415-042A-1C05
ORCID iD
0000-0002-0143-9758
Google Scholar ID
https://scholar.google.pt/citations?hl=pt-PT&user=02W9yO4GjtsC
Researcher Id
B-6386-2009
Scopus Author Id
58241831600

Email addresses

  • mcasal@bio.uminho.pt (Professional)

Telephones

Telephone
  • 253604044 (Professional)

Addresses

  • Departamento de Biologia, Universidade do Minho. Campus de Gualtar, 4710-057, Braga, Braga, Portugal (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Genetics and Heredity
  • Natural sciences - Biological Sciences - Microbiology
  • Engineering and Technology - Industrial Biotechnology - Bioplastics

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2008
Concluded
 Biologia (Título de Agregado)
Universidade do Minho Escola de Ciências, Portugal
 Unanimidade
2002
Concluded
 Ciências (Doutoramento)
Major in Sem especialidade
Universidade do Minho, Portugal
"Transporte e Utilização de Ácidos Dicarboxílicos Nas Leveduras Kluyveromyces Sp. e Saccharomyces Cerevisiae: uma Abordagem Fisiológica, Bioquímica e Genética" (THESIS/DISSERTATION)
1995
Concluded
 Ciências (Doutoramento)
Major in Biologia
Universidade do Minho, Portugal
"Estudos Fisiológicos e Moleculares Sobre o Transporte de Ácido Láctico e de Outros Ácidos Monocarboxílicos em Sacharomyces cerevisiae e Torulaspora delbruecki " (THESIS/DISSERTATION)
1985
Concluded
 Biologia- ramo científico (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
 16 valores
Affiliation

Teaching in Higher Education

Category
Host institution		 Employer
2009/06/25 - Current Full Professor (University Teacher) Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Positions / Appointments

Category
Host institution		 Employer
2016/06/13 - 2017/10/27 Organic Unit President Universidade do Minho, Portugal
Universidade do Minho, Portugal

Others

Category
Host institution		 Employer
2015/01/01 - 2026/08/01 Director of the FCT_PhD Programme in Applied and Environmental Microbiology http://phdmicrobiology.pt/ Universidade do Minho, Portugal
2018/09/01 - 2022/08/30 Deputy Diretor for Research and Innovation of CBMA Universidade do Minho, Portugal
2017/11/27 - 2018/10/25 Vice-Rector for Education Universidade do Minho, Portugal
2013/07/29 - 2016/07/30 Head of the CBMA - Centro de Biologia Molecular e Ambiental (R&D unit). CBMA was evaluated as Excelente. Universidade do Minho, Portugal
2009/10/01 - 2016/06/12 Member (elected) of the General Council Universidade do Minho, Portugal
2011/02/08 - 2015/02/01 Member of the Scientific Council (elected) Universidade do Minho, Portugal
2007/06/01 - 2013/02/01 Deputy Diretor for Research and Innovation of CBMA Universidade do Minho, Portugal
2006/03/08 - 2012/02/01 Head of the Biology Department (elected 3 times) Universidade do Minho, Portugal
Projects

Contract

Designation Funders
2016/06 - Current EcoAgriFood: Innovative green products and processes to promote Agri-Food BioEconomy
1
Principal investigator
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
 NORTE-01-0145-FEDER-000009.
Concluded
2021/01/01 - 2025/12/31 ARNET - Aquatic Research Network
LA/P/0069/2020
10.54499/LA/P/0069/2020
Universidade do Minho, Portugal

Universidade do Algarve, Portugal

Instituto Politécnico de Leiria, Portugal

Universidade Nova de Lisboa, Portugal

Instituto Universitário de Ciências Psicológicas Sociais e da Vida, Portugal

FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal

Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade de Lisboa Faculdade de Ciências, Portugal

Universidade de Coimbra, Portugal

Universidade de Évora, Portugal

Agência Regional para o Desenvolvimento da Investigação Tecnologia e Inovação, Portugal

Centro de Ciências do Mar e do Ambiente, Portugal

Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2021/06/01 - 2024/05/31 MetaFungal-Metabolismo de ácidos carboxílicos em Infeções Fúngicas
PTDC/BIA-MIC/5246/2020
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2021/04/01 - 2023/03/31 River2Ocean – Socio-ecological and biotechnological solutions for the conservation and valorisation of aquatic biodiversity in the Minho Region
NORTE-01-0145-FEDER-000068
Researcher
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
 Comissao de Coordenacao e Desenvolvimento Regional do Norte
Concluded
2018/09/18 - 2021/08/21 ECOBiB. Eco-Innovative Bag-In-Box Solutions
POCI-01-0247-FEDER-033997
Researcher
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
 Ministério da Economia
Concluded
2017/09 - 2021/08 YEASTDOC - Yeast Biotechnology Doctoral Training Programme
764927
Principal investigator
European Commission, Belgium
 EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
Concluded
2016/05/01 - 2020/09/01 Structural-functional studies of carboxylic acid transporters: Novel tools in production optimization using industrial microbes
PTDC/BIA-MIC/5184/2014
Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2015/10 - 2020/05/01 Trans-Acids. Structural-functional studies of carboxylic acid transporters: Novel tools in production optimization using industrial microbes
Provided by PTCRIS: 143819
PTDC/BIA-MIC/5184/2014
Principal investigator
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2016/10/01 - 2020/03/31 FunBioPlas - Novel synthetic biocomposites for biomedical devices
ERA-IB-2-6/0004/2014
Researcher
Universidade do Minho, Portugal

Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2019/01/01 - 2019/12/31 CENTRE OF MOLECULAR AND ENVIRONMENTAL BIOLOGY
UID/BIA/04050/2019
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2015/01 - 2017/12 CENTRE OF MOLECULAR AND ENVIRONMENTAL BIOLOGY
Provided by PTCRIS: 147364
BIA/UI4050/2014
UID/BIA/04050/2013
Principal investigator
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2014/01/01 - 2015/12/31 Incentive - UI 4050 - 2014
Incentivo/BIA/UI4050/2014
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2014/04 - 2015/09 Unravelling the determinants of xylanase function and stability and enhancing the biotechnological value of a highly active Antarctic xylanase.
Provided by PTCRIS: 134797
EXPL/BBB-BIO/1772/2013
Researcher
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2013/06 - 2015/09 ACROSS-Development of AntimiCRObial Spider Silk sutures for preventing surgical site infections
Provided by PTCRIS: 125502
Researcher
Fundação para a Ciência e a Tecnologia
2012/03/01 - 2015/08/31 Mechanisms of Candida glabrata biofilms tolerance to antifungal agents
PTDC/SAU-MIC/119069/2010
Provided by PTCRIS: 119069
Researcher
Instituto de Biotecnologia e Bioengenharia, Portugal

Universidade do Minho, Portugal

Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2014/01/01 - 2014/12/31 Strategic Project - UI 4050 - 2014
PEst-OE/BIA/UI4050/2014
Provided by PTCRIS: 137277
Incentivo/BIA/UI4050/2014
Principal investigator
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal

Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2014/01/01 - 2014/12/31 Strategic Project - UI 4050 - 2014
PEst-OE/BIA/UI4050/2014
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2013/12/31 Projecto Estratégico - UI 4050 - 2011-2012
PEst-C/BIA/UI4050/2011
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2011/01/01 - 2013/12/31 Strategic Project - UI 4050 - 2011-2012
PEst-C/BIA/UI4050/2011
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010/06 - 2013/11 PhenoMet - Integrative Pheno-Metabolomic and Genomic Approaches for Saccharomyces cerevisiae winemaking yeasts
Provided by PTCRIS: 103392
PTDC/AGR-ALI/103392/2008
Researcher
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal

Universidade Católica Portuguesa, Portugal

Universidade de Aveiro Centro de Estudos do Ambiente e do Mar, Portugal

Universidade do Minho Centro de Engenharia Biológica, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010/04/01 - 2013/09/30 Chimera - Development of new chimeric proteins to be used in the fabrication of a novel biomaterial for bone regeneration application
PTDC/EBB-EBI/109093/2008
Provided by PTCRIS: 109093
Researcher
Universidade do Minho, Portugal

Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010/04 - 2013/09 BIOMYR: Towards the metabolic engineering of beta-myrcene pathway of Pseudomonas sp. M1: functional genomics and structural biochemistry approaches
Provided by PTCRIS: 104980
PTDC/EBB-BIO/104980/2008
Researcher
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal

Universidade de Lisboa Instituto Superior Técnico, Portugal

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica António Xavier, Portugal

Instituto de Biotecnologia e Bioengenharia, Portugal

Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2009/01/01 - 2012/06/30 MONOLIPO - MONOOLEIN-BASED LIPOPLEXES: PHYSICOCHEMICAL CHARACTERIZATION AND STUDY OF THEIR POTENTIAL AS NON-VIRAL VECTORS
PTDC/QUI/69795/2006
Provided by PTCRIS: 69795
Researcher
Centro de Física das Universidades do Minho e do Porto, Portugal

Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2009/01/01 - 2011/12/31 Implementation of a Nacional Facility for DNA Microarrays: Phase II
PTDC/BIA-BCM/64745/2006
Provided by PTCRIS: 64745
Researcher
Universidade de Aveiro, Portugal

Universidade de Aveiro Centro de Estudos do Ambiente e do Mar, Portugal

Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2005/07 - 2008/12 LeVini - Novel approaches in the wine industry: Exploration of yeast genetic resources and development of diagnostic molecular tools
Provided by PTCRIS: 56102
POCI/AGR/56102/2004
Researcher
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho, Portugal

Universidade do Minho Departamento de Biologia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2005/06 - 2008/12 PermYeast - Molecular biology of the monocarboxylic acids permeases in yeast: from functional to structural analysis
Provided by PTCRIS: 57812
POCI/BIA-BCM/57812/2004
Researcher
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal

Universidade do Minho Departamento de Biologia, Portugal

Universidade do Minho, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2005/05/01 - 2008/06/30 ElastM - Elastomeric protein-based polymers: from biological synthesis to mouldings
POCI/CTM/57177/2004
Provided by PTCRIS: 57177
Principal investigator
Universidade do Minho Departamento de Biologia, Portugal

Universidade do Minho, Portugal

Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2005/05/01 - 2007/12/31 Leveduras produtoras de fenóis voláteis: uma grande preocupação na indústria dos vinhos que necessita de ser compreendida
POCI/AGR/56771/2004
Provided by PTCRIS: 56771
Researcher
Universidade de Lisboa Instituto Superior de Agronomia, Portugal

Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Universidade do Minho, Portugal

Universidade de Lisboa Centro de Investigação em Agronomia Alimentos Ambiente e Paisagem, Portugal

Universidade de Évora, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2004 - 2007 FunCarb – Funcionalização de materiais biomédicos usando um domínio de ligação a carbohidratos. Functionalization of biomedical materials using a carbohydrate binding domain
Projeto POCTI/ BIO/45356/2002
 Fundação para a Ciência e a Tecnologia
2004 - 2007 EnoSafe – Segurança e controlo de qualidade de vinhos: implementação de técnicas rápidas para monitorização e rastreabilidade microbiológica.
programa AGRO - Medida 8 - Desenvolvimento Tecnológico e Demonstração – Acção 8.1 Desenvolvimento Experimental e de Demonstração (DE&D), projeto 762
programa AGRO - Medida 8 - Desenvolvimento Tecnológico e Demonstração Acção 8.1 Desenvolvimento Experimental e de Demonstração (DE&D), projeto 762
 Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior
2003 - 2006 - Málico/FCT - Construção de estirpes de Saccharomyces cerevisiae com capacidade de remover ácido málico sob controlo genético. Engineering of Saccharomyces cerevisiae species able to remove malic acid under genetic control
POCTI/BIO/38106/2001
 Fundação para a Ciência e a Tecnologia
2001 - 2004 JENesis - Caracterização genética e molecular de transportadores de ácidos monocarboxílicos em leveduras. Molecular and genetic analysis of monocarboxylic acid transporters in yeasts
POCTI- Projecto POCTI/ 1999/ BME / 36625
 Fundação para a Ciência e a Tecnologia
1996 - 1999 Optimização de Fermentações Alcoólicas: Construção de Estirpes da Levedura Saccharomyces cerevisiae com capacidade de remoção de ácidos fracos do meio de fermentação
GRANT_NUMBER: PRAXIS 2/2.1/BIO/1068/95
 Fundação para a Ciência e a Tecnologia
1996 - 1999 Isolamento e caracterização de leveduras: aplicações em enologia
programa PAMAF 2029 - Projeto 2025
 Ministério da Agricultura
1986 - 1989 A biotecnologia vegetal no melhoramento das castas do vinho verde. Aplicação de técnicas de cultura in vitro.
cont 819.86.03
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book
  1. Casal, Margarida; Schuller, Dorit Elisabeth; Machado, Sofia; Cerdeira, António; Duarte, F. L.; Campos, Ângela; Moura, Fernando; Miguel, Vasco; Batista, Julião. Corresponding author: Casal, Margarida. Manual de boas práticas de produção vitivinícola (BPPV). 2009.
Book chapter
  1. Machado, Raul; da Costa, André; Pereira, Ana Margarida Macedo Bernardes; Rodriguez-Cabello, José Carlos; Casal, Margarida; Machado R; da Costa A; et al. "Elastins-based antimicrobial particles for delivery of bioactive compounds". Humana Press, 2020.
    10.1007/978-1-0716-0319-2_3
  2. Casal, Margarida; Queirós, Odília; Talaia, Gabriel; Ribas, David Manuel Nogueira; Paiva, Sandra; Casal, M.; Queirós, O.; et al. "Carboxylic acids plasma membrane transporters in Saccharomyces cerevisiae". Springer, 2016.
    10.1007/978-3-319-25304-6_9
  3. Casal, Margarida; Cunha, A. M.; Machado, Raul; Casal, M.; Cunha, A.M.; Machado, R.. "Future trends for recombinant protein-based polymers: the case study of development and application of silk-elastin-like polymers". Wiley, 2014.
    10.1002/9781118676646.ch12
  4. Machado, Raul; Bessa, Paulo C.; Reis, R. L.; Rodriguez-Cabello, José Carlos; Casal, Margarida; MacHado, R.; Bessa, P.C.; et al. "Elastin-based nanoparticles for delivery of bone morphogenetic proteins". In npj Biofilms and Microbiomes. 2012.
    10.1007/978-1-61779-953-2_29
  5. Castanheira, Pedro; Moreira, Susana Margarida Gomes; Casal, Margarida; Gama, F. M.; Faro, Carlos. "Recombinant laforin for structural studies". In npj Biofilms and Microbiomes. InTech, 2011.
  6. Leonor, I.B.; Gomes, S.; Bessa, P.C.; Mano, J.F.; Reis, R.L.; Casal, M.. "New biomineralization strategies for the use of natural-based polymeric materials in bone-tissue engineering". In npj Biofilms and Microbiomes. 2008.
    10.1533/9781845694814.2.193
  7. Schuller, Dorit Elisabeth; Pais, Célia; Casal, Margarida. "Métodos moleculares de identificação de leveduras do vinho". 2004.
  8. Queirós, Odília; Casal, Margarida; Moradas-Ferreira, Pedro; Leão, Cecília. "Gene Disruption in the Yeast Kluyveromyces lactis". In Non-Conventional Yeasts in Genetics, Biochemistry and Biotechnology, 161-167. Springer Berlin Heidelberg, 2003.
    10.1007/978-3-642-55758-3_25
  9. Queiros, Odilia; Casal, Margarida; Ferreira, Pedro Moradas; Leão, Cecília. "PCR¿based strategy for gene disruption in Kluyvermyces lactis". In Non-Conventional Yeasts in Genetics, Biochemistry and Biotechnology, edited by Wolf, Klaus; Breunig, Karin D.; Barth, Gerold. Springer Berlin Heidelberg, 2003.
    Published
  10. Casal, Margarida; Pais, M. Salomé S.. "Micropropagation of Vitis Vinifera from “Vinho Verde” Region of Portugal: A Method for Grapevine Leafroll Virus Elimination". In Plant Aging, 327-334. Springer US, 1990.
    10.1007/978-1-4684-5760-5_40
Conference abstract
  1. Pereira, A.M.; da Costa, A.; Casal, M.; Machado, R.; Machado, Raul; da Costa, André; Sencadas, Vitor; et al. Corresponding author: Machado, R.. "Genetically engineered protein-based polymers for the development of antimicrobial materials". Paper presented in 4th International Conference on Natural Fibers ¿ Smart Sustainable Solutions, Boston, 2019.
    Published
  2. Machado, Raul; Gomes, Diana; da Costa, André; Pereira, Ana Margarida; Casal, Margarida; da Costa, André; Pereira, Ana; Machado, Raul. "Development and antimicrobial evaluation of genetically engineered protein-based/essential oil composites". Paper presented in 256th ACS National Meeting & Exposition, Boston, 2018.
    Published
  3. Talaia, Gabriel; Gournas, Christos; Saliba, Elie; Antunes, Cláudia Barata; Casal, Margarida; André, Bruno; Diallinas, George; Paiva, Sandra. "Signals and mechanisms of endocytosis of eukaryotic lactate transporters". 2017.
  4. Costa, André Manuel Abreu; Silva, Andreia Maria; Pereira, Ana Margarida Macedo Bernardes; Gomes, Andreia Castro; Sencadas, Vítor João Gomes Silva; Casal, Margarida; Machado, Raul; Gomes, Andreia C. "Electrospun silk-elastin fibres functionalized with silver nanoparticles as antibacterial wound dressings". 2017.
  5. Costa, André Manuel Abreu; Sencadas, Vítor João Gomes Silva; Lanceros-Méndez, S.; Gomes, Andreia Castro; Rodríguez-Cabello, J.C.; Casal, Margarida; Machado, Raul; Gomes, Andreia C. "Antibacterial protein-based fibres: combining recombinant DNA technology with electrospinning". 2017.
  6. Talaia, Gabriel; Saliba, Elie; Gournas, Christos; Barata-Antunes, Cláudia; André, Bruno; Diallinas, George; Casal, Margarida; Paiva, Sandra. "A novel pathway for the endocytic regulation of Jen1 lactate transporter of Saccharomyces cerevisiae". 2017.
  7. Alves, Rosana Maria Abreu; Stavroula, Kastora; Pinho, Eva Patrícia Paiva Santos; Rodrigues, Célia Fortuna; Silva, Sónia Carina; Casal, Margarida; Brown, Alistair; Henriques, Mariana; Paiva, Sandra. "Global transcriptome characterization of Candida glabrata biofilms in response to acetate and fluconazole". 2017.
  8. Talaia, Gabriel; Casal, Margarida; Diallinas, George; Paiva, Sandra. "Analysis of the intracellular traffic and turnover of yeast membrane transporters using a novel domain swap strategy". 2017.
  9. Alves, Rosana Maria Abreu; Kastora, Stavroula; Pinho, Eva Patrícia Paiva Santos; Rodrigues, Célia Fortuna; Silva, Sónia Carina; Casal, Margarida; Alistair, Brown; et al. "Impact of alternative carbon sources and antifungal treatment on Candida glabrata biofilms' transcription profile". 2016.
    10.13140/RG.2.2.29676.77444
  10. Barroca, Mário Jorge Faria; Rodrigues, Paulo; Branca, Fernanda; Casal, Margarida; Collins, Tony. "High-level biosynthesis of a silk-elastin-like protein in E. coli: fed batch production and antibiotic free selection". 2016.
  11. Alves, Rosana; Mota, Sandra; Silva, Sónia Carina; Rodrigues, Célia Fortuna; Brown, Alistair J.; Henriques, Mariana; Casal, Margarida; et al. "Lactic acid increases the susceptibility of Candida albicans to fluconazole". 2016.
    10.13140/RG.2.2.36387.66089
  12. Talaia, Gabriel; Casal, Margarida; Diallinas, George; Paiva, Sandra. "The study of the endocytic trafficking of the yeast monocarboxylate transporter Jen1 from Saccharomyces cerevisiae". 2015.
  13. Talaia, Gabriel; Casal, Margarida; Diallinas, George; Paiva, Sandra. "Study of intracellular trafficking of yeast monocarboxylate transporter Jen1 from Saccharomyces cerevisiae". 2015.
  14. Costa, André Manuel Abreu; Machado, Raul; Sencadas, Vítor João Gomes Silva; Lanceros-Méndez, S.; Gomes, Andreia Castro; Rodríguez-Cabello, José Carlos; Casal, Margarida. "Electrospun fibres of an elastin-like polymer functionalized with an antimicrobial domain". 2015.
  15. Azevedo-Silva, João; Queirós, Odília; Ko, YH; Pedersen, Peter; Preto, Ana; Casal, Margarida. "Characterization of 3-bromopyruvate uptake in breast cancer cells". Paper presented in 4th Annual Meeting of the International Society of Proton Dynamics in Cancer, 2014.
  16. Collins, Tony; Barroca, Mário Jorge Faria; Branca, Fernando; Silva, João Azevedo; Costa, André da; Machado, Raul; Casal, Margarida. "Optimising the production of a silk-elastin-like protein in E. coli: overcoming acetate accumulation and plasmid instability". 2013.
  17. Costa, André da; Machado, Raul; Ribeiro, Artur J.; Gomes, Andreia; Rodríguez-Cabello, José Carlos; Casal, Margarida. "A synthetic biology approach for the development of recombinant protein-based polymers exhibiting antimicrobial properties". 2013.
  18. Collins, Tony; Barroca, Mário Jorge Faria; Branca, Fernando; Silva, João Azevedo; Costa, André da; Machado, Raul; Casal, Margarida. "Optimising a cell factory system for the bioproduction of silk-elastin-like polymers.". 2013.
  19. Machado, Raul; da Costa, André; Ribeiro, Artur; Gomes, Andreia Castro; Rodriguez-Cabello, José Carlos; Casal, Margarida. "Development of an ex vivo assay for the characterization of a new elastin-like polymer with antimicrobial properties". Paper presented in TERM STEM 2013, Porto, 2013.
    Published
  20. Machado, Raul; da Costa, André; Sencadas, Vitor; Gomes, Andreia Castro; Lanceros-Méndez, Senentxu; Rodríguez-Cabello, José Carlos; Casal, Margarida. "Electrospun recombinant Protein-Based Polymers fibre matrices for skin regeneration". Paper presented in TERM STEM 2013, 2013.
    Published
  21. Campos, A. R.; Oliveira, B.; Machado, Raul; Collins, Tony; Azevedo-Silva, João; da Costa, André; Immonen, K.; Wikström, L.; Casal, Margarida. "Novel nanocellulose reinforced recombinant protein based polymer composites". Paper presented in 1st Internacional Conference on Natural Fibres (ICNF2013), 2013.
    Published
  22. Machado, Raul; da Costa, André; Sencadas, Vitor; Azevedo-Silva, João; Collins, Tony; Arias, Francisco Javier; Lanceros-Méndez, Senentxu; Rodríguez-Cabello, José Carlos; Casal, Margarida. "Synthesis and processing of recombinant silk and elastin copolymers". Paper presented in 1st Internacional Conference on Natural Fibres (ICNF2013), 2013.
    Submitted
  23. Duarte, Ricardo Franco; Carrelo, Laura; Dequin, Sylvie; Santos, Manuel A. S.; Casal, Margarida; Schuller, Dorit Elisabeth; Cambon, Brigitte; Carreto, Laura. "Microevolutionary changes of commercial Saccharomyces cerevisiae strains recovered from vineyard environments identified by comparative genome hybridization on array.". 2012.
  24. Costa, André da; Machado, Raul; Ribeiro, Artur J.; Gomes, Andreia; Rodríguez-Cabello, José Carlos; Casal, Margarida. "Antibacterial and antifungal activity of a new solvent-cast film based on a functionalized elastin-like polymer". 2011.
  25. Duarte, Ricardo Franco; Carreto, Laura; Cambon, Brigitte; Dequin, Sylvie; Santos, Manuel A. S.; Casal, Margarida; Schuller, Dorit Elisabeth. "Comparative genomics of commercial Saccharomyces cerevisiae isolates recovered from vineyard environments". 2011.
  26. Duarte, Ricardo Franco; Carreto, Laura; Cambon, Brigitte; Dequin, Sylvie; Santos, Manuel A. S.; Casal, Margarida; Schuller, Dorit Elisabeth. "Genetic characterization of commercial Saccharomyces cerevisiae isolates recovered from vineyard environments using comparative genome hybridization on array (aCGH)". 2011.
  27. Pessoa, Joana Sá; Viegas, Sandra; Rocha, Gabriel Azevedo Carreira Talaia da; Diallinas, George; Paiva, Sandra; Arraiano, Cecilia; Casal, Margarida. "Discovery and initial characterization of members of the new YaaH family of microbial acetate transporters". 2011.
  28. Rocha, Gabriel Azevedo Carreira Talaia da; Diallinas, George; Casal, Margarida; Paiva, Sandra. "Pinpointing intracellular trafficking determinants in the Jen1 yeast lactate transporter by domain swap". 2011.
  29. Pereira, Filipa Maria Rodrigues; Ribeiro, Gabriela; Casal, Margarida; Johansson, Björn; Paiva, Sandra. "Screening for interactions with predicted soluble domains of the yeast lactate transporter JEN1". 2011.
  30. Costa, A.; Machado, Raul; Casal, Margarida. "Solvent-cast films of an elastin-like polymer fused to an antimicrobial peptide, ABP-CM4, exhibits high antibacterial activity against pseudomonas aeruginosa". 2011.
  31. Becuwe, Michel; Vieira, N.; Vincent, O.; Haguenauer-Tsapis, Rosine; Paiva, Sandra; Casal, Margarida. "A metabolic switch on a yeast arrestin connects glucose signaling to transporter endocytosis". 2011.
  32. Pessoa, Joana Sá; Silva, Isabel Soares; Myrianthopoulos, Vassilios; Mikros, Emmanuel; Diallinas, George; Casal, Margarida. "Identification of amino acid residues critical for the substrate translocation in lactate permease JEN1p of saccharomyces cerevisiae". 2011.
  33. Bessa, Daniela Sofia Santos; Paiva, Sandra; Moreira, Roxana; Casal, Margarida; Queirós, Odília. "Functional characterization of a Yarrowia lipolytica gene family coding for carboxylic acids permeases homologues". 2011.
  34. Collins, Tony; Silva, J. Azevedo; Costa, A.; Machado, Raul; Casal, Margarida; Silva, João Azevedo; Costa, André da; Branca, Fernando. "Key stress factors and parameters for batch production optimisation of silk-elastin-like proteins in E. coli". 2011.
  35. Machado, Raul; Arias, F. J.; Rodríguez-Cabello, José Carlos; Casal, Margarida. "High level expression and facile purification of recombinant silk-elastin-like polymers in auto-induction shake flask cultures". 2011.
  36. Silva, J. Azevedo; Machado, Raul; Reis, R. L.; Rodríguez-Cabello, José Carlos; Casal, Margarida. "Creating new functional biomaterials: construction and production of Bone Morphogenetic 2-ELP hybrid proteins". 2010.
  37. Pessoa, Joana Sá; Silva, Isabel Soares; Diallinas, George; Casal, Margarida. "Identification of amino acid residues critical for distinguishing mono- and di-Carboxylate substrates in JEN 1". 2010.
  38. Costa, André da; Machado, Raul; Matamá, Maria Teresa; Rodríguez-Cabello, José Carlos; Paulo, Artur Cavaco; Casal, Margarida. "Production and purification of recombinant antimicrobial peptides by exploiting the termoresponsiveness of the elastin-like polymer based on the VPAVG sequence". 2010.
  39. Vieira, E.; Neves, J. Drumonde; Gambon, Brigitte; Valero, Eva; Gomes, Ana Catarina; Sousa, Susana; Lima, Maria Teresa; et al. "A colecção de Saccharomyces cerevisiae para a selecção de novas estirpes de vinificação". 2010.
  40. Vieira, E.; Neves, J. Drumonde; Gambon, Brigitte; Valero, Eva; Gomes, Ana Catarina; Sousa, Susana; Lima, Maria Teresa; et al. "A Saccharomyces cerevisiae bio-databank for winemaking strain selection". 2010.
  41. da Costa, André; Machado, Raul; Matamá, Teresa; Rodríguez-Cabello, José Carlos; Cavaco-Paulo, Artur; Casal, Margarida. "Production and purification of recombinant antimicrobial peptides by exploiting the thermoresponsiveness of the elastin-like polymer based on the VPAVG sequence". Paper presented in XXXV Jornadas Portuguesas de Genética, 2010.
    Published
  42. Machado, Raul; Arias, Francisco Javier; Rodríguez-Cabello, José Carlos; Casal, Margarida. "Engineering of recombinant silk and elastin copolymers". 2010.
    Published
  43. Duarte, Ricardo Franco; Casal, Margarida; Schuller, Dorit Elisabeth. "The phenotypic heterogeneity of saccharomyces cerevisiae strains from natural environments". 2008.
  44. Bessa, P. C.; Balmayor, E. R.; Cerqueira, M. T.; Rada, Tommaso; Gomes, M. E.; Neves, N. M.; Azevedo, H.S; Casal, Margarida; Reis, R. L.. "Silk nanoparticles for delivery of human BMP-2 in bone regenerative medicine applications". 2008.
  45. Bessa, P. C.; Cerqueira, M. T.; Rada, Tommaso; Gomes, M. E.; Neves, N. M.; Casal, Margarida; Reis, R. L.. "Expression, purification and bioactivity of recombinant human bone morphogenetic protein-4,-9,-10,-11 and-14 produced in Escherichia coli for tissue engineering applications". 2008.
  46. Pereira, Leonor; Duarte, Ricardo Franco; Ramos, P.; Alemão, F.; Gomes, P.; Sousa, S.; Santos, Manuel A. S.; et al. "Microsatellite analysis reveals populational structures of Saccharomyces cerevisiae strains from different appellations of origin and grape varieties". 2008.
  47. Machado, Raul; Padrão, Jorge; Nobre, Alexandra; Arias, F. J.; Teixeira, J. A.; Cunha, A. M.; Rodríguez-Cabello, José Carlos; Casal, Margarida; Cunha, António. "Construction and bioproduction of a "green" synthetic protein-based polymer exhibiting a smart behaviour". 2008.
  48. Pereira, Leonor; Casal, Margarida; Schuller, Dorit Elisabeth. "Differential malic acid degradation by indigenous and commercial Saccharomyces cerevisiae wine strains". 2007.
  49. Moreira, Susana Margarida Gomes; Domingues, Lucília; Gama, F. M.; Casal, Margarida. "Cloning, expression and purification of carbohydrate binding module in Pichia Pastoris: functionalization of biomedical materials using a carbohydrate binding domain". 2007.
  50. Pereira, Leonor; Machado, Sofia; Ramos, P.; Alemão, F.; Gomes, P.; Sousa, S.; Santos, Manuel A. S.; et al. "Comparison of Saccharomyces cerevisiae populations from different appellations of origin and grape varieties by microsatellite analysis". 2007.
  51. Silva, D.; Padrão, Jorge; Machado, Raul; Teixeira, J. A.; Casal, Margarida; Nobre, Alexandra. "Response surface optimization of the culture medium for production of elastin-like polymers by Escherichia coli". 2007.
  52. Moreira, Susana; Domingues, Lucília; Casal, Margarida; Gama, F. M.. "Cloning and expression of a recombinant human CBD (carbohydrate binding domain) : a comparison between two expression models". 2007.
  53. Moreira, Susana Margarida Gomes; Domingues, Lucília; Gama, F. M.; Casal, Margarida. "Production of the human carbohydrate binding module from laforin protein : a comparative study between bacterial and yeast expression systems". 2007.
  54. Machado, Raul; Correia, Cristina; Padrão, Jorge; Nobre, Alexandra; Cunha, A. M.; Rodríguez-Cabello, J. Carlos; Casal, Margarida. "Construction, bioproduction and characterization of Protein Based Polymers: exploiting the sequence of naturally occurring Elastin and Silk fibroin". 2007.
  55. Padrão, Jorge; Silva, Dina; Machado, Raul; Nobre, Alexandra; Casal, Margarida. "Elastin-like protein production kinetics at different environmental conditions in Escherichia coli". 2007.
  56. Pereira, Leonor; Schuller, Dorit Elisabeth; Queirós, Odília; Ferreira, Pedro Moradas; Casal, Margarida. "Malic acid degradation by indigenous and commercial Saccharomyces cerevisiae wine strains". 2006.
  57. Moreira, Susana Margarida Gomes; Domingues, Lucília; Gama, F. M.; Casal, Margarida. "Cloning, expression and purification of a carbohydrate binding module in Pichia pastoris". 2006.
  58. Moreira, Susana; Domingues, Lucília; Casal, Margarida; Gama, F. M.. "Improving the solubility of a recombinant human CBD (carbohydrate binding domain)". 2006.
  59. Padrão, Jorge; Machado, Raul; Nobre, Alexandra; Casal, Margarida. "Physical and chemical optimization of a synthetic medium for Pichia pastoris growth". 2006.
  60. Valero, Eva; Cambon, Brigitte; Dequin, Sylvie; Casal, Margarida. "Comparison of vineyard-associated Saccharomyces cerevisiae populations by microsatellite analysis". 2006.
  61. Bessa, Paulo C.; Pedro, A.; Nobre, Alexandra; Dungl, P.; Banerjee, A.; Dopler, D.; Klosch, B.; et al.. "Expression, purification and in vitro biological activity from human recombinant BMP-2 produced by a novel approach". 2006.
  62. Schuller, Dorit Elisabeth; Alves, Hugo; Cambon, Brigitte; Dequin, Sylvie; Casal, Margarida. "Genetic instability of a commercial Saccharomyces cerevisiae strain". 2006.
  63. Queiros, Odilia; Pereira, Leonor; Paiva, Sandra; Moradas-Ferreira, Pedro; Casal, Margarida. "Kljen1 and Kljen2 are essencial for the transport of monocarboxylic and dicarboxylic acids in the yeast Kluyveromyces lactis". Paper presented in Yeast Genetics and Molecular Biology Meeting, Princeton, 2006.
  64. Schuller, Dorit Elisabeth; Sampaio, Paula; Pais, Célia; Casal, Margarida. "Genetic structure of vineyard-associated Saccharomyces cerevisiae populations revealed by microsatellite analysis". 2005.
  65. Schuller, Dorit Elisabeth; Vieira, Teresa; Casal, Margarida. "E-learning strategies in the teaching of Microbiology and Genetics - a practical approach for primary and secondary schools". 2005.
  66. Schuller, Dorit Elisabeth; Alves, Hugo; Cambon, Brigitte; Dequin, Sylvie; Casal, Margarida. "Genetic instability of commercial Saccharomyces cerevisiae strains recovered from vineyard’s microflora". 2005.
  67. Dellinger, B.; Machado, Sofia; Schuller, Dorit Elisabeth; Casal, Margarida. "Commercial yeast utilization and genetic structure of vineyard-associated Saccharomyces cerevisiae populations revealed by microsatellite analysis". 2005.
  68. Valero, Eva; Schuller, Dorit Elisabeth; Cambon, Brigitte; Casal, Margarida; Dequin, Sylvie. "Dissemination and survival of commercial wine yeast in the vineyard: a large-scale, three years study". 2005.
  69. Schuller, Dorit Elisabeth; Valero, Eva; Dequin, Sylvie; Casal, Margarida. "Molecular methods evaluation for the typing of Saccharomyces cerevisiae wine strains". 2004.
  70. Valero, Eva; Schuller, Dorit Elisabeth; Cambon, Brigitte; Casal, Margarida; Dequin, Sylvie. "Dissémination des levures œnologiques dans le vignoble". 2004.
  71. Schuller, Dorit Elisabeth; Alves, Hugo; Sampaio, Paula; Pais, Célia; Casal, Margarida. "Biodiversity and phenotypic characterization of Saccharomyces cerevisiae strains isolated from the Vinho Verde Wine Region". 2004.
  72. Paiva, Sandra; Devaux, Frederic; Barbosa, Sónia; Jacq, Claude; Casal, Margarida. "Ady2p is essential for the acetate pemease activity in the yeast Saccharomyces cerevisae". 2004.
  73. Ramalho, Patrícia A.; Paiva, Sandra; Casal, Margarida; Ramalho, Maria Teresa; Cardoso, M. Helena; Paulo, Artur Cavaco. "Reductive biological treatment of textile effluents". 2004.
  74. Ramalho, Patrícia A.; Paiva, Sandra; Paulo, Artur Cavaco; Casal, Margarida; Ramalho, Maria Teresa; Cardoso, M. Helena. "The azoreductase of yeast cells: a new feature of an old enzyme". 2004.
  75. Queirós, Odília; Paiva, Sandra; Ferreira, Pedro Moradas; Casal, Margarida. "Molecular and physiological characterization of mono- and dicarboxylic acids permeases in the yeast Kluyveromyces lactis". 2003.
  76. Schuller, Dorit Elisabeth; Alves, Hugo; Dequin, Sylvie; Casal, Margarida. "Disseminação de leveduras comerciais em ecossistemas vitivinícolas". 2003.
  77. Schuller, Dorit Elisabeth; Alves, Hugo; Sampaio, Paula; Pais, Célia; Casal, Margarida. "Molecular diversity and phenotypic characterization of Saccharomyces sp. strains isolated from the Vinho Verde Wine Region". 2003.
  78. Schuller, Dorit Elisabeth; Valero, Eva; Gambon, Brigitte; Casal, Margarida; Dequin, Sylvie. "Commercial yeast strains do not significantly disseminate in vineyard ecosystems". 2003.
  79. Schuller, Dorit Elisabeth; Valero, Eva; Dequin, Sylvie; Casal, Margarida. "The genetic characterization of Saccharomyces cerevisiae commercial enological strains : a survey of molecular typing techniques". 2003.
  80. Queiros, Odilia; Casal, Margarida; Moradas-Ferreira, Pedro; Leão, Cecília. "Molecular and physiological characterization of monocarboxylic acids permeases in Kluyveromyces lactis". Paper presented in XXIth International Conference on Yeast Genetics and Molecular Biology, Gotemburgo, 2003.
  81. Schuller, Dorit Elisabeth; Cambon, Brigitte; Quintas, L.; Blondin, Bruno; Dequin, Sylvie; Casal, Margarida. "Monitoring the spreading of industrial yeast populations in the winery environment". 2002.
  82. Schuller, Dorit Elisabeth; Quintas, L.; Dequin, Sylvie; Casal, Margarida. "Avaliação da dispersão da levedura starter - Zymaflore Vl1 de Laffort Oenologie, em ambiente natural na proximidade de adegas da Região dos Vinhos Verdes". 2002.
  83. Schuller, Dorit Elisabeth; Andrade, Raquel P.; Silva, Isabel Soares; Casal, Margarida. "Permease de monocarboxilatos de Saccharomyces cerevisiae (JEN1): expressão constitutiva em S. cerevisiae e sobre-expressão em Pichia pastoris". 2002.
  84. Queiros, Odilia; Casal, Margarida; Moradas-Ferreira, Pedro; Leão, Cecília. "Molecular studies on malic acid transport in the yeast Kluyveromyces marxianus". Paper presented in 27th Meetting of the FEBS and Pan-American Association Molecular Biology., 2001.
  85. Queiros, Odilia; Casal, Margarida; Moradas-Ferreira, P.; Leão, Cecília. "Molecular studies on a Kluyveromyces marxianus malate inducible plasma membrane protein". Paper presented in XXth International Conference on Yeast Genetics and Molecular Biology, Praga, 2001.
  86. Queiros, Odilia; Casal, Margarida; Moradas-Ferreira, Pedro; Leão, Cecília. "Kluyveromyces lactis heterologous gene expression improves the ability of Saccharomyces cerevisiae to use malate". Paper presented in XVII Small Meeting on Yeast Transport and Energetics (SMYTE), 1999.
  87. Queiros, Odilia; Casal, Margarida; Moradas-Ferreira, Pedro; Leão, Cecília. "Engineering of a Saccharomyces cerevisiae strain improves the ability to use malic acid". Paper presented in XIX International Conference on Yeast Genetics and Molecular Biology, Rimini, 1999.
  88. Queiros, Odilia; Casal, Margarida; Althoff, S.; Moradas-Ferreira, Pedro; Leão, Cecília. "Phenotypic characterisation of Kluyveromyces marxianus deficient mutants on malate transport". Paper presented in XV Small Meeting on Yeast Transport and Energetics (SMYTE), Morelos, 1997.
  89. Queiros, Odilia; Casal, Margarida; Moradas-Ferreira, Pedro; Leão, Cecília. "Isolation and characterization of Kluyveromyces marxianus deficient mutants on malate transport". Paper presented in XVII International Conference on Yeast Genetics and Molecular Biology, Lisboa, 1995.
Conference paper
  1. Rendulic, Toni; Alves, João; Soares-Silva, Isabel João; Nevoigt, Elke; Casal, Margarida. "Engineering the activity and specificity of Saccharomyces cerevisiae Acetate Transporter Ady2/Ato1". 2021.
  2. Silva, Maria Antónia Sousa Correia; Ribas, David Manuel Nogueira; Casal, Margarida; Soares-Silva, Isabel João. "Characterization of Cyberlindnera jadinii carboxylate permeases by heterologous expression in Saccharomyces cerevisiae". 2019.
  3. Senra, Emanuel Sousa; Silva, Maria Antónia Sousa Correia; Ribas, David Manuel Nogueira; Casal, Margarida; Soares-Silva, Isabel João. "Characterization of novel plasma membrane carboxylate transporters from non-conventional yeasts". 2019.
  4. Silva, Maria Antónia Sousa Correia; Ribas, David Manuel Nogueira; Casal, Margarida; Soares-Silva, Isabel João. "Characterization of Cyberlindnera jadinii carboxylate transporters by heterologous expression in S. cerevisiae". 2019.
  5. Silva, Maria Antónia Sousa Correia; Ribas, David Manuel Nogueira; Casal, Margarida; Soares-Silva, Isabel João; Sousa-Silva, M.. "Identification of novel carboxylate transporters encoded in the Cyberlindnera jadinii transportome by heterologous expression in S. cerevisiae". 2019.
  6. Gonçalves, Anabela Ferreira; da Costa, André; Casal, Margarida; Gomes, Andreia C; Machado, Raul. "A molecular biology platform for the production of cytokines and cytokine-functionalized materials". 2019.
    Published
  7. Silva, Maria Antónia Sousa Correia; Ribas, David Manuel Nogueira; Franco-Duarte, Ricardo; Pais, Célia; Casal, Margarida; Soares-Silva, Isabel João; Sousa-Silva, M.. "Screening of non-Saccharomyces wild yeasts for biotechnological applications". 2019.
  8. Silva, Maria Antónia Sousa Correia; Vieira, Daniel; Ribas, David Manuel Nogueira; Soares, Pedro; Casal, Margarida; Soares-Silva, Isabel João. "Exploring the Cyberlindnera jadinii transportome for the identification of novel carboxylate transporters". 2019.
  9. Sousa-Silva, M.; Ribas, David Manuel Nogueira; Casal, Margarida; Soares-Silva, Isabel João. "Characterization of Cyberlindnera jadinii carboxylate permeases by heterologous expression in Saccharomyces cerevisiae". 2019.
  10. Alves, Rosana Maria Abreu; Timmermans, Bea; Van Ende, Mieke; Casal, Margarida; Van Dijck, Patrick; Paiva, Sandra. "Functional characterization of putative acetate transporters and channels in the human fungal pathogen Candida glabrata". 2019.
  11. Sousa-Silva, M.; Vieira, Daniel; Ribas, David Manuel Nogueira; Soares, Pedro; Casal, Margarida; Soares-Silva, Isabel João; Silva, Maria Antónia Sousa Correia. "Exploring the Cyberlindnera jadinii yeast transportome to uncover novel carboxylate transporters for biotechnological applications". 2019.
  12. Alves, Rosana Maria Abreu; Timmermans, Bea; Van Ende, Mieke; Henriques, Mariana; Casal, Margarida; Van Dijck, Patrick; Paiva, Sandra. "Role of carboxylate transporters during carbon adaptation in Candida glabrata". 2019.
  13. Alves, Rosana Maria Abreu; Gonçalves, Alexandra Carmo Gomes; Timmermans, Bea; Van Ende, Mieke; Casal, Margarida; Van Dijck, Patrick; Paiva, Sandra. "Acetate assimilation is an integral part of Candida glabrata survival in the human host". 2019.
  14. Rendulic, Toni; Silva, João Pedro Azevedo; Ribas, David Manuel Nogueira; Castagnoli, Davide; Paiva, Sandra; Soares-Silva, Isabel João; Nevoigt, Elke; Casal, Margarida. "Engineering of AceTr membrane transporters to improve organic acid production in yeast". 2019.
  15. Rendulic, Toni; Silva, João Pedro Azevedo; Xiberras, Joeline; Medonça Bahia, Frederico; Ribas, David Manuel Nogueira; Castagnoli, Davide; Paiva, Sandra; et al. "Exploring plasma membrane transporters to improve organic acid production in yeast – Characterization and engineering". 2019.
  16. Rendulic, Tony; Barbosa, Augusto Alexandre Costa; Pereira, Cátia; Barata, Cláudia; Mendes, Filipa; Pereira, Humberto; Ferreira, João Carlos; et al. "Yeast as a Biotechnological factory". 2019.
  17. Silva, Maria Antónia Sousa Correia; Ribas, David Manuel Nogueira; Casal, Margarida; Soares-Silva, Isabel João; Sousa-Silva, M.. "The Cyberlindnera jadinii carboxylate transporters Ady2 and Jen1 homologs are functional in Saccharomyces cerevisiae". 2018.
  18. Silva, Maria Antónia Sousa Correia; Ribas, David Manuel Nogueira; Franco-Duarte, Ricardo; Pais, Célia; Casal, Margarida; Soares-Silva, Isabel João; Sousa-Silva, M.. "Exploring organic acid producer microorganisms – Identification, morpho- and physiological characterization of wild yeast strains". 2018.
  19. Azevedo-Silva, João; Ribas, David; Castagnoli, Davide; Sa-Pessoa, Joana; Athayde, Diogo; Soares-Silva, Isabel; Archer, Margarida; Casal, Margarida. "Exploring the function and structure of the acetate transporter family". 2018.
    10.1016/j.freeradbiomed.2018.04.389
  20. Silva, Maria Antónia Sousa Correia; Ribas, David Manuel Nogueira; Casal, Margarida; Soares-Silva, Isabel João. "Functional characterization of Cyberlindnera jadinii carboxylate transporters in Saccharomyces cerevisiae". 2018.
  21. Silva, Maria Antónia Sousa Correia; Ribas, David Manuel Nogueira; Casal, Margarida; Soares-Silva, Isabel João. "Functional characterization of Cyberlindnera jadinii carboxylate transporters in Saccharomyces cerevisiae". 2018.
  22. Ribas, David Manuel Nogueira; Soares-Silva, Isabel João; Vieira, Daniel; Silva, Maria Antónia Sousa Correia; Sá-Pessoa, Joana; Silva, João Pedro Azevedo; Viegas, Sandra; et al. "The Ady2 “NPAPLGL(M/S)” motif is critical for acetate uptake and binding". 2018.
  23. Salgado, Ana; Côrte-Real, Manuela; Casal, Margarida. "Comunicar ciência: a formação em competências transversais dos estudantes de doutoramento da Escola de Ciências da Universidade do Minho". 2018.
  24. Sousa-Silva, M.; Ribas, David Manuel Nogueira; Casal, Margarida; Soares-Silva, Isabel João. "Functional characterization of Cyberlindnera jadinii carboxylate transporters in Saccharomyces cerevisiae". 2018.
  25. da Costa, André; Sencadas, Vítor João Gomes Silva; Lanceros-Méndez, S.; Gomes, Andreia C; Rodriguez-Cabello, Jose; Casal, Margarida; Machado, Raul. "Genetically engineered protein-based polymers with broad antimicrobial activity for biomedical applications". 2018.
  26. Pereira, Ana Margarida Macedo Bernardes; da Costa, André; Dias, Simoni Campos; Sa-Correia, Isabel; Casal, Margarida; Machado, Raul. "Development of antimicrobial protein-based polymers for biomedical applications". 2018.
    10.1016/j.freeradbiomed.2018.04.412
  27. Casal, Margarida. "The diversity of links between the functional and structural features of carboxylate transporters in prokaryotic and eukaryotic cells: Implications in health and biotechnology". 2018.
    10.1016/j.freeradbiomed.2018.04.556
  28. Vieira, Joana Margarida Pereira; Azevedo-Silva, João; Preto, Ana; Casal, Margarida; Queirós, Odília. "Monocarboxylate transporters expression is influenced by different extracellular conditions determining the effect of 3-bromopyruvate in colorectal cancer cells". 2018.
  29. Gonçalves, Alexandra; Alves, Rosana Maria Abreu; Casal, Margarida; Dijck, Patrick van; Paiva, Sandra. "Candida glabrata biofilm development on medical devices is modulated by the presence of alternative carbon sources.". 2017.
  30. Machado, Raul; Costa, André Manuel Abreu; Pereira, Ana Margarida Macedo Bernardes; Silva, Andreia Maria; Gomes, Diana; Gomes, Andreia Castro; Lanceros-Méndez, S.; et al. "Genetically engineered Silk-Elastin-Like Proteins as a versatile platform for the development of new biomaterials". 2017.
  31. Talaia, Gabriel; Saliba, Elie; Gournas, Christos; Barata-Antunes, Cláudia; André, Bruno; Diallinas, George; Casal, Margarida; Paiva, Sandra. "A novel pathway for the endocytic regulation of Jen1 lactate transporter of Saccharomyces cerevisiae". 2017.
  32. Sousa-Silva, M.; Ribas, David Manuel Nogueira; Casal, Margarida; Soares-Silva, Isabel João; Silva, Maria Antónia Sousa Correia. "Heterologous expression of Candida utilis carboxylic acid transporters in Saccharomyces cerevisiae". 2017.
  33. Alves, Rosana Maria Abreu; Kastora, Stavroula; Pinho, Eva Patrícia Paiva Santos; Rodrigues, Célia Fortuna; Silva, Sónia Carina; Casal, Margarida; Alistair, Brown; et al. "Impact of alternative carbon sources and antifungal treatment on Candida glabrata biofilms' transcription profile". 2016.
    10.13140/RG.2.2.29676.77444
  34. Talaia, Gabriel; Casal, Margarida; Diallinas, George; Paiva, Sandra. "Analysis of the intracellular traffic and turnover of yeast membrane transporters using a novel domain swap strategy". 2016.
  35. Costa, André Manuel Abreu; Machado, Raul; Rodríguez-Cabello, J.C.; Gomes, Andreia Castro; Casal, Margarida; Gomes, Andreia C. "Creation of antimicrobial biopolymers by the use of recombinant DNA technology". 2016.
  36. Alves, Rosana; Kastora, Stavroula; Pinho, Eva; Rodrigues, Célia Fortuna; Silva, Sónia Carina; Casal, Margarida; Brown, Alistair J.; Henriques, Mariana; Paiva, Sandra. "Impact of alternative carbon sources and antifungal treatment on Candida glabrata biofilms transcription profile". 2016.
  37. Marques, Margarida; Casal Ribeiro, Helder. "Towards an authentic architecture - Auguste Perret". 2016.
  38. Pereira, Ana Margarida Macedo Bernardes; Machado, Raul; Costa, André Manuel Abreu; Ribeiro, Artur J.; Collins, Tony; Gomes, Andreia C; Leonor, I. B.; et al. "Genetically engineered silk-based composite biomaterials functionalized with fibronectin type-II that promote cell adhesion". 2016.
  39. Talaia, Gabriel; Casal, Margarida; Diallinas, George; Paiva, Sandra. "The study of the endocytic trafficking of the yeast monocarboxylate transporter Jen1 from Saccharomyces cerevisiae". 2015.
  40. Talaia, Gabriel; Casal, Margarida; Diallinas, George; Paiva, Sandra. "Study of intracellular trafficking of yeast monocarboxylate transporter Jen1 from Saccharomyces cerevisiae". 2015.
  41. Pereira, Ana Margarida Macedo Bernardes; Machado, Raul; Bernardo, T.; Costa, André Manuel Abreu; Ribeiro, Artur J.; Collins, Tony; Gomes, Andreia C; et al. "Advanced silk-based genetic polymers with improved cell adhesion properties". 2015.
  42. Machado, Raul; Silva, Andreia Maria; Costa, André Manuel Abreu; Gomes, Andreia C; Rodríguez-Cabello, J.C.; Lanceros-Méndez, S.; Sencadas, Vítor João Gomes Silva; Casal, Margarida; Gomes, Andreia Castro. "Antimicrobial Electrospun Membranes of Selp/Ag Composites". 2015.
  43. Costa, André Manuel Abreu; Machado, Raul; Sencadas, Vítor João Gomes Silva; Lanceros-Méndez, S.; Gomes, Andreia C; Rodríguez-Cabello, José Carlos; Casal, Margarida. "Electrospun fibres of an elastin-like polymer functionalized with an antimicrobial domain". 2015.
  44. Costa, André Manuel Abreu; Machado, Raul; Ribeiro, Artur J.; Collins, Tony; Thiagarajan, V.; Neves-Petersen, M.T.; Rodríguez-Cabello, J.C.; et al. "Synthetic Protein Biotechnology approaches for the creation of antimicrobial biopolymers". 2015.
  45. Talaia, Gabriel; Casal, Margarida; Diallinas, George; Paiva, Sandra. "Study of intracellular trafficking of yeast monocarboxylate transporter Jen1 from Saccharomyces cerevisiae". 2015.
  46. Padrão, Jorge; Machado, Raul; Casal, Margarida; Rodrigues, L. R.; Dourado, Fernando; Lanceros-Méndez, S.; Sencadas, V.. "Antibacterial performance of bovine lactoferrin-fish gelatine electrospun nanocomposites". 2014.
  47. Pereira, A. M.; Bernardo, T. C.; Costa, André da; Collins, Tony; Machado, Raul; Leonor, I. B.; Casal, Margarida; Reis, R. L.. "Development of new chimeric proteins for tissue engineering". 2013.
    10.1002/term.1822
  48. Costa, André da; Machado, Raul; Ribeiro, Artur J.; Gomes, Andreia C; Rodríguez-Cabello, José Carlos; Casal, Margarida. "Antibacterial and antifungal activity of a new solvent-cast film based on a functionalized elastin-like polymer". 2013.
  49. Collins, Tony; Silva, João Azevedo; Costa, André da; Branca, Fernando; Machado, Raul; Casal, Margarida. "Key stress factors and parameters for production optimisation of silk-elastin-like proteins in E. coli BL21(DE3)". 2013.
  50. Duarte, Ricardo Franco; Carrelo, Laura; Dequin, Sylvie; Santos, Manuel A. S.; Casal, Margarida; Schuller, Dorit Elisabeth; Cambon, Brigitte. "Microevolutionary changes of commercial Saccharomyces cerevisiae strains recovered from vineyard environments identified by comparative genome hybridization on array.". 2012.
  51. Duarte, Ricardo Franco; Carreto, Laura; Mendes, Inês; Cambon, Brigitte; Dequin, Sylvie; Santos, Manuel A. S.; Casal, Margarida; Schuller, Dorit Elisabeth. "Intra-strain phenotypic and genomic variability of the commercial Saccharomyces cerevisiae strains Zymaflore VL1 recovered from vineyard environments". 2012.
  52. Diallinas, George; Soares-Silva, Isabel; Pessoa, Joana Sa; Myrianthopoulos, Vassilios; Mikros, Emmanuel Mikros; Casal, Margarida. "Identification of a Substrate Translocation Trajectory in the Inward-Facing Conformation of the Monocarboxylate/H plus Symporter Jen1". 2011.
  53. Pessoa, Joana Sá; Silva, Isabel Soares; Myrianthopoulos, Vassilios; Mikros, Emmanuel; Diallinas, George; Casal, Margarida. "A substrate translocation trajectory in the monocarboxylate/h+ symporter jen1". 2011.
  54. Duarte, Ricardo Franco; Carreto, Laura; Cambon, Brigitte; Dequin, Sylvie; Santos, Manuel A. S.; Casal, Margarida; Schuller, Dorit Elisabeth. "Microevolutionary changes of commercial Saccharomyces cerevisiae strains recovered from vineyard environments identified by comparative genome hybridization on array". 2011.
  55. Vieira, E.; Neves, J. Drumonde; Lima, Maria Teresa; Araújo, Isabel M.; Casal, Margarida; Schuller, Dorit Elisabeth. "A new high-throughput method for the rapid extraction of yeast DNA". 2011.
  56. Leon, S.; Becuwe, Michel; Vieira, N.; Lara, D.; Casal, Margarida; Vincent, O.; Paiva, Sandra; Haguenauer-Tsapis, Rosine. "Connecting glucose signalling to ubiquitin-dependent transporter endocytosis: arrestin the culprit!". 2011.
  57. Becuwe, Michel; Vieira, N.; Vincent, O.; Haguenauer-Tsapis, Rosine; Paiva, Sandra; Casal, Margarida. "A metabolic switch on a yeast arrestin connects glucose signaling to transporter endocytosis". 2011.
  58. Machado, Raul; García-Arévalo, C.; Arias, F. J.; Rodríguez-Cabello, José Carlos; Casal, Margarida. "Tunable morphology and structural properties of recombinant silk-elastin biopolymers by electrospinning". 2011.
  59. Costa, A.; Machado, Raul; Casal, Margarida. "Solvent-cast films of an elastin-like polymer fused to an antimicrobial peptide, ABP-CM4, exhibits high antibacterial activity against pseudomonas aeruginosa". 2011.
  60. Vieira, E.; Neves, J. Drumonde; Gambon, Brigitte; Valero, Eva; Gomes, Ana Catarina; Sousa, Susana; Lima, Maria Teresa; et al. "A collection of indigenous saccharomyces cerevisiae strains from appellations of origin in Portugal and France". 2010.
  61. Vieira, E.; Neves, J. Drumonde; Machado, Raul; Silva, Paulo; Gomes, Ana Catarina; Sousa, Susana; Ramos, P.; et al. "A colecção de estirpes autóctones de Saccharomyces cerevisiae das principais regiões vitivinícolas portuguesas". 2010.
  62. Pessoa, Joana Sá; Silva, Isabel Soares; Diallinas, George; Casal, Margarida. "Identification of amino acid residues critical for distinguishing mono- and di-carboxylate permeases in the lactate/pyruvate:H+symporter subfamily". 2010.
  63. Pessoa, Joana Sá; Silva, Isabel Soares; Diallinas, George; Casal, Margarida. "Identification of amino acid residues critical for distinguishing mono- and di-Carboxylate substrates in JEN 1". 2010.
  64. Silva, J. Azevedo; Costa, A.; Machado, Raul; Rodríguez-Cabello, José Carlos; Casal, Margarida. "Use of elastin like polymer (VPAVG)220 fusion TAGS for recombinant protein, production and purification". 2010.
  65. Machado, Raul; Araújo, Rita; Silva, Carla Manuela Pereira Marinho da; Bessa, Paulo C.; Cunha, A. M.; Teixeira, J. A.; Paulo, Artur Cavaco; et al. "Recombinant elastin-like polymers: from the design towards application". 2009.
  66. Balmayor, Elizabeth Rosado; Bessa, P. C.; Tuzlakoglu, Kadriye; Azevedo, H. S.; Casal, Margarida; Reis, R. L.. "Novel biodegradable polymeric microparticles for the localized delivery of differentiation agents in bone tissue engineering applications". 2008.
  67. Pereira, Leonor; Machado, Sofia; Ramos, P.; Alemão, F.; Gomes, P.; Sousa, S.; Santos, Manuel A. S.; et al. "Populational analysis of Saccharomyces cerevisiae strains from different appellations of origin and grape varieties by microsatellite analysis". 2008.
  68. Moreira, Susana Margarida Gomes; Domingues, Lucília; Casal, Margarida; Gama, F. M.. "Development of a strategy to functionalize dextrin-based hydrogel for animal cell cultures". 2008.
  69. Duarte, Ricardo Franco; Casal, Margarida; Schuller, Dorit Elisabeth. "Bioinformatic approaches for the genetic and phenotypic characterization of a Saccharomyces cerevisiae wine yeast collection". 2007.
  70. Silva, D.; Padrão, Jorge; Machado, Raul; Teixeira, J. A.; Casal, Margarida; Nobre, Alexandra. "Response surface optimization of the culture medium for production of elastin-like polymers by Escherichia coli". 2007.
  71. Padrão, Jorge; Silva, Dina; Machado, Raul; Nobre, Alexandra; Casal, Margarida. "Elastin-like protein production kinetics at different environmental conditions in Escherichia coli". 2007.
  72. Dellinger, B.; Graça, Magda Maria Couto da Silva; Casal, Margarida; Schuller, Dorit Elisabeth. "Identification of wine related yeast species by capillary electrophoresis single- strand conformation polymorphism". 2007.
  73. Moreira, Susana Margarida Gomes; Domingues, Lucília; Gama, F. M.; Casal, Margarida; Moreira, Susana. "Cloning and expression of carbohydrate binding module in Pichia pastoris". 2005.
  74. Schuller, Dorit Elisabeth; Alves, Hugo; Cambon, Brigitte; Dequin, Sylvie; Casal, Margarida. "Genetic instability of commercial Saccharomyces cerevisiae strains recovered from vineyard’s microflora". 2005.
  75. Schuller, Dorit Elisabeth; Vieira, Teresa; Casal, Margarida. "E-learning strategies in the teaching of Microbiology and Genetics - a practical approach for primary and secondary schools". 2005.
  76. Schuller, Dorit Elisabeth; Valero, Eva; Dequin, Sylvie; Casal, Margarida. "Survey of molecular methods for the typing of wine yeast strains". 2004.
  77. Schuller, Dorit Elisabeth; Valero, Eva; Cambon, Brigitte; Casal, Margarida; Dequin, Sylvie. "Commercial yeast strains do not disseminate significantly in winery ecosystems of wine producing regions in France and Portugal". 2003.
  78. Silva, Isabel Soares; Andrade, Raquel P.; Schuller, Dorit Elisabeth; Casal, Margarida. "Exploring genetic tools for the overexpression of the lactate permease Jen1p of Saccharomyces cerevisiae: constitutive expression in S. cerevisiae and heterologous expression in Pichia pastoris". 2003.
  79. Silva, Isabel Soares; Schuller, Dorit Elisabeth; Andrade, Raquel P.; Baltazar, Fátima; Cássio, Fernanda; Casal, Margarida. "Functional expression of the lactate permease Jen1p of Saccharomyces cerevisiae in Pichia pastoris". 2003.
  80. Schuller, Dorit Elisabeth; Casal, Margarida; Leão, Cecília. "Constitutive expression and functionality of the gene JEN1 of Saccharomyces cerevisiae in the presence of glucose". 2000.
  81. Pereira, J.A.; Casal, Susana; Oliveira, Beatriz; Ferreira, Margarida A.. "Azeites varietais das Cv. Cobrançosa, Madural e Verdeal: influência do tempo de armazenamento da azeitona no teor de tocoferóis do azeite". 1999.
  82. Pereira, J.A.; Oliveira, Beatriz; Casal, Susana; Ferreira, Margarida A.. "Olive oil quality versus strorage of varietal olives (Fatty acid profile, acidity and peroxide value).". 1999.
  83. Paiva, Sandra; Casal, Margarida; Leão, Cecília. "Genetic characterization of monocarboxylic acids transporters of Saccharomyces cerevisiae.". Paper presented in 16th Small Meeting on Yeast Transport and Energetics (SMYTE), Bratislava, 1998.
    Published
Conference poster
  1. Pereira-Vieira, Joana; Weber, Daniela; Sónia Pires Celeiro; Granja, Sara; Reis, Rui Manuel; Moura, Rute S; Queiros, Odilia; et al. "Treatment with 3-bromopyruvate boosts the effect of chemotherapy in acute myeloid leukemia". Paper presented in Annual Congress of EACR, 2025.
  2. Gomes-Gonçalves, Alexandra; Genechten, Wouter; Ataíde, Patrícia; Barata-Antunes, Cláudia; Ghasemi, Faezeh; Casal, Margarida; Teixeira, Miguel A.C.; et al. "Iron homeostasis in Candida albicans is modulated by the presence of lactate". Paper presented in 31th Annual BSM Symposium – amAIzing Microbiology: demystifying AI for all microbiologists, Brussels, Belgium, 2025.
  3. Ataíde, Patrícia; Ghasemi, Faezeh; Cláudia Barata-Antunes; Gomes-Gonçalves, Alexandra; Alves, Rosana; Casal, Margarida; Brown, Alistair J. P.; et al. "Exploring Ato6 subcellular dynamics in Candida albicans". Paper presented in II CBMA Open Day & III PhD | Bio Symposium, 2025.
  4. Ataíde, Patrícia; Ghasemi, Faezeh; Cláudia Barata-Antunes; Gomes-Gonçalves, Alexandra; Alves, Rosana; Casal, Margarida; Brown AJP; et al. "Fungi and Nutrition: Exploring Ato6 subcellular dynamics in Candida albicans". Paper presented in II CBMA Open Day & III PhD|BIO Symposium, 2025.
  5. Pereira-Vieira, Joana; Granja, Sara; Sónia Pires Celeiro; Ana Catarina Barbosa Matos; Ana Preto; Queiros, Odilia; Ko, YH; Casal, Margarida; Maria de Fátima Monginho Baltazar. "3-Bromopiruvato aumenta o efeito da quimioterapia na leucemia mieloide aguda por um mecanismo mediado por ROS". Paper presented in 6ºENJIC – LPCC, 2024.
  6. Pereira-Vieira, Joana; Weber, Daniela; Silva, Sâmia; Ana Catarina Barbosa Matos; Granja, Sara; Reis, Rui Manuel; Ko, YH; et al. "Targeting glucose metabolism in acute myeloid leukemia (AML) chemoresistance". Paper presented in 6th ASPIC International Congress, 2024.
  7. Ghasemi, Faezeh; Cláudia Barata-Antunes; Ataíde, Patrícia; Alves, João; Isabel, Soares-Silva; Alves, Rosana; Gomes-Gonçalves, Alexandra; et al. "Differential affinity and expression patterns among Candida albicans Ato family members". Paper presented in I CBMA Open Day & II PhD|Bio Symposium, February 02, 2024, University of Minho, Braga, Portugal, 2024.
  8. Gomes-Gonçalves, Alexandra; Van Genechten, Wouter; Cláudia Barata-Antunes; Ghasemi, Faezeh; Alves, Rosana; Casal, Margarida; Ariño, Joaquin; et al. "Transcriptional response of Candida albicans cells to the presence of lactic acid and environmental pH". Paper presented in I CBMA Open Day & II PhD|Bio Symposium, 2024.
  9. Ghasemi, Faezeh; Ataíde, Patrícia; Cláudia Barata-Antunes; Gomes-Gonçalves, Alexandra; Alves, Rosana; Casal, Margarida; Alistair Brown; et al. "Expression and Subcellular Localization Patterns of Ato2 transport protein of Candida albicans". Paper presented in UMinho Research & Innovation Open Days, January 30-31, 2024; University of Minho, Braga, Portugal, 2024.
  10. Bragança, Ana Rita; Silva, Rui; Casal, Margarida; Isabel, Soares-Silva; Machado, Raul. Corresponding author: Machado, Raul. "Bioprospection of marine microorganisms as a source of inspiration to design novel antimicrobial peptides.". Paper presented in UMinho Research & Innovation Open Days, 2024.
  11. Ghasemi, Faezeh; Cláudia Barata-Antunes; Ataíde, Patrícia; Alves, João; Isabel, Soares-Silva; Alves, Rosana; Gomes-Gonçalves, Alexandra; et al. Corresponding author: Ghasemi, Faezeh. "Candida albicans Acetate transporter orthologues (ATOs): docking and expression studies". Paper presented in UMinho Research & Innovation Open Days, January 30-31, 2024; University of Minho, Braga, Portugal,, 2024.
  12. Gomes-Gonçalves, Alexandra; Van Genechten, Wouter; Cláudia Barata-Antunes; Ghasemi, Faezeh; Alves, Rosana; Casal, Margarida; Ariño, Joaquin; et al. "Transcriptomic analysis of C. albicans cells in distinct metabolic conditions". Paper presented in UMinho Research & Innovation Open Days, 2024.
  13. Patrícia Ataíde; Ghasemi, Faezeh; Cláudia Barata-Antunes; Gomes-Gonçalves, Alexandra; Alves, Rosana; Casal, Margarida; Brown, Alistair; et al. "Fungi and Nutrition: Expression and Subcellular Localization Patters of Ato2 Transport Protein of Candida albicans". Paper presented in UMinho Research & Innovation Open Days, January 30-31, 2024; University of Minho, Braga, Portugal, 2024.
  14. Bragança A.R.; Marques Silva A.R.; Gomes J.; Collins, Tony; Casal, Margarida; Soares Silva I.; Machado R.; et al. Corresponding author: Machado, Raul. "Unlocking the biotechnological potential of marine microorganisms: the River2Ocean project's contribution to the blue bioeconomy". Paper presented in Microbiotec¿23: Congress of Microbiology and Biotechnology 2023, Covilhã, Portugal, 2023.
  15. Ghasemi, Faezeh; Alexandra Gomes-Gonçalves; Vitor Fernandes; Cláudia Barata-Antunes; Alves, Rosana; Alves Joao; Isabel João soares Silva; et al. "The role of Nutrient Transporters in Candida albicans pathogenesis". Paper presented in IV International Meeting of the Portuguese Society of Genetics (IMPSG)-Braga, Portugal, 2023.
  16. Bragança A.R.; Gomes J.; Marques Silva A.R.; Collins, Tony; Casal, Margarida; Soares Silva I.; Machado R. "The River2Ocean project: isolation, genotyping and phenotyping of marine microorganisms as key drivers for sustainable innovation.". Paper presented in IV International Meeting of the Portuguese Society of Genetics (IMPSG IV), 2023.
  17. Alves, Rosana; Cláudia Barata-Antunes; Ghasemi, Faezeh; Vitor Fernandes ; Alexandra Gonçalves; Casal, Margarida; Alistair J. P. Brown; Patrick Van Dijck; Sandra Paiva. "ATO transporters as essential elements of cellular function and homeostasis in Candida albicans pathogenesis.". Paper presented in FEMS Congress 2023 (Hamburg, Germany), 2023.
  18. Gomes-Gonçalves, Alexandra; Ghasemi, Faezeh; Cláudia Barata-Antunes; Fernandes, Vitor; Alves, Rosana; Casal, Margarida; Wouter Van Genechten; Patrick Van Dijck; Paiva, Sandra. Corresponding author: Gomes-Gonçalves, Alexandra. "Metabolic Induced Pathogenesis in Candida albicans: the role of ATO transporters and carboxylic acids". Paper presented in I Symposium PhDBio, 2023.
  19. Pereira-Vieira, Joana; Maria Barreto-Gonçalves; Ana Catarina Barbosa Matos; Queiros, Odilia; Ko, YH; Casal, Margarida; Maria de Fátima Monginho Baltazar. "Characterization of metabolic profile of acute myeloid leukaemia cells resistant to chemotherapy". Paper presented in Cancer Metabolism EACR, 2022.
  20. Vieira, Joana; Sónia Pires-Celeiro; Granja, Sara; Barbosa-Matos, Catarina; H Ko, Young ; Preto, Ana; Odília Queirós; Casal, Margarida; Baltazar, Fátima. "Targeting glycolytic metabolism as a therapeutic strategy for Acute Myeloid Leukemia". Paper presented in EACR 2021 Virtual Congress, 2021.
  21. Pereira-Vieira, Joana; Granja, Sara; Ana Catarina Barbosa Matos; Ko, YH; Ana Preto; Queiros, Odilia; Casal, Margarida; et al. "Non-toxic concentrations of 3-bromopyruvate sensitize acute myeloid leukemia (AML) cells to chemotherapy by inducing oxidative stress". Paper presented in EACR-AACR with ASPIC, Lisbon, 2020.
  22. Gomes-Gonçalves, Alexandra; Alves, Rosana; Casal, Margarida; Van Dijck, Patrick; Paiva, Sandra. "Presence of alternative carbon sources modulates Candida glabrata biofilm development on medical devices". Paper presented in V Simpósio PDBMA, 2019.
  23. Alves, Rosana; Bea Timmermans; Mieke Van Ende; Mariana Henriques; Margarida Paula Pedra Amorim Casal; Patrick Van Dijck; Sandra Paiva. "Role of carboxylate transporters during carbon adaptation". Paper presented in HFP2019: Molecular Mechanisms of Host-Pathogen Interactions and Virulence in human fungal Pathogens (La Colle sur Loup, France), 2019.
  24. Pereira-Vieira, Joana; Sara Granja; Ana Catarina Barbosa Matos; Ko, YH; Ana Preto; Casal, Margarida; Maria de Fátima Monginho Baltazar. "3-Bromopyruvate sensitizes Acute Myeloid Leukemia cell lines to chemotherapy". Paper presented in 26th Porto Cancer Meeting, 2019.
  25. Cunha, Andrea; Ana Margarida Barbosa; Casal, Margarida; Queiros, Odilia. "Comparison of 3-bromopyruvate effect in a parental and resistant breast cancer cell line". Paper presented in XI Jornadas Científicas do Instituto Universitário de Ciências da Saúde/IV Congresso da Associação Portuguesa de Ciências Forenses, 2019.
  26. Pereira, A. M.; da Costa, André; Dias, S. C.; Sá-Correia, I.; Casal, Margarida; Machado, Raul. "Elastin-based tags for the biotechnological production of antimicrobial peptides". Paper presented in Congress of Microbiology and Biotechnology ¿Microbiotec19, 2019.
  27. Alves, Rosana; Kastora, Stavroula L.; Margarida Paula Pedra Amorim Casal; Alistair J. P. Brown; Mariana Henriques; Sandra Paiva; Alves, Rosana Maria Abreu; et al. "Adapting to survive: how Candida glabrata responds to environmental physiological constrains". Paper presented in 14th ASM Conference on Candida and Candidiasis (Providence, RI, USA), 2018.
  28. da Costa, André; Sencadas, Vitor; Pereira, Ana Margarida; Lanceros-Méndez, Senentxu; Gomes, Andreia Castro; Rodríguez-Cabello, José Carlos; Casal, Margarida; Machado, Raul. "Bioinspired antibacterial protein fibres: from recombinant DNA technology to electrospinning". Paper presented in International Symposium on Bioinspired Macromolecular Systems (ISBMS), 2017.
  29. Pereira, Ana Margarida; da Costa, André; Dias, Simoni Campos; Sá-Correia, Isabel; Casal, Margarida; Machado, Raul. "Fabrication of polymeric protein-based materials with antimicrobial properties for biomedical applications". Paper presented in International Symposium on Bioinspired Macromolecular Systems (ISBMS), 2017.
  30. da Costa, André; Sencadas, Vitor; Lanceros-Méndez, Senentxu; Gomes, Andreia Castro; Rodríguez-Cabello, José Carlos; Casal, Margarida; Machado, Raul. "Antimicrobial activity of genetically engineered-derived materials". Paper presented in XLI Jornadas Portuguesas de Genética, 2017.
  31. Pereira, Ana Margarida; da Costa, André; Sá-Correia, Isabel; Casal, Margarida; Machado, Raul. "Genetically engineered antimicrobial biopolymers as promising therapeutics for biomedical application". Paper presented in XLI Jornadas Portuguesas de Genética, 2017.
  32. Gomes, Diana; da Costa, André; Pereira, Ana Margarida; Casal, Margarida; Machado, Raul. "Antimicrobial activity of genetically engineered silk-elastin protein films containing essential oils". Paper presented in XIX Congresso Nacional de Bioquímica SPB2016, 2016.
  33. da Costa, André; Machado, Raul; Rodríguez-Cabello, José Carlos; Gomes, Andreia Castro; Casal, Margarida. "Recombinant DNA technology as tool for antimicrobial biopolymers creation". Paper presented in XIX Congresso Nacional de Bioquímica SPB2016, 2016.
  34. Pereira, Ana Margarida; Machado, Raul; Bernardo, Telma; da Costa, André; Ribeiro, Artur; Collins, Tony; Gomes, Andreia Castro; et al. "Silk-based biomaterials with improved cell adhesion properties". Paper presented in XIX Congresso Nacional de Bioquímica SPB2016, 2016.
  35. Silva, A. M.; da Costa, André; Pereira, Ana Margarida; Gomes, Andreia Castro; Sencadas, Vitor; Casal, Margarida; Machado, Raul. "Production of antimicrobial protein-based materials via one-step synthesis of silver nanoparticles". Paper presented in XIX Congresso Nacional de Bioquímica SPB2016, 2016.
  36. Azevedo-Silva, J.; Oliveira, CSF; Queirós, O; Ribas, D; Côrte-Real, M; Baltazar, F; Goffeau, A; et al. "Transport of monocarboxylic acids in cancer cells: implications of short chain fatty acids and 3-bromopyruvate for cancer therapy.". Paper presented in SMYTE 34, Chania, Crete, Greece, 2016.
  37. Ribas, David; Sá-Pessoa, Joana; Paiva, Sandra; Ruohonen, Laura; Penttilä, Merja; Casal, Margarida. "Yeast as a tool to express carboxylic acid transporters with biotechnological interest.". Paper presented in PYFF6 - Sixth Conference on Physiology of Yeasts and Filamentous Fungi, 2016.
  38. Machado, Raul; Silva, A. M.; da Costa, André; Pereira, Ana Margarida; Gomes, Andreia Castro; Sencadas, Vitor; Casal, Margarida. "Antimicrobial activity of genetically engineered silk-elastin-like composite materials". Paper presented in XL Jornadas Portuguesas de Genética, 2016.
  39. Gomes, Diana; da Costa, André; Pereira, Ana Margarida; Casal, Margarida; Machado, Raul. "Formulation of biocomposites based on recombinant proteins and plant essential oils for the development of active wound dressings". Paper presented in XL Jornadas Portuguesas de Genética, 2016.
  40. Vieira, Joana; Barbosa, Ana; Moreira, Roxana; Casal, Margarida; Queirós, Odília. "3-Bromopyruvate induces cytotoxicity and inhibits glycolysis and migratory capacity in glioblastomas and colorectal cancer cell lines". Paper presented in 2nd ASPIC Interntional Congress, 2016.
  41. Azevedo-Silva, J.; Queirós, O.; Ribeiro, A; Baltazar, F; Ko YH; Petersen PL; Preto, A.; Casal, Margarida. "The extracellular pH influences the cytotoxicity and transport of 3-Bromopyruvate in breast cancer cells". Paper presented in 2nd ASPIC International Congress, 2016, IPO-Porto, 2016.
  42. Granja, Sara; João Azevedo-Silva ; Preto, Ana; Queirós, Odília; Baltazar, Fatima; Casal, Margarida. "Targeting glycolysis in acute myeloid leukemia: therapeutic applications". Paper presented in XIX National Congress of Biochemistry, 2016.
  43. da Costa, André; Machado, R.; Sencadas, V.; Lanceros-Méndez, S.; Gomes, A.C.; Rodriguez-Cabello, J.C.; Casal, Margarida. "Electrospun fibres of an elastin-like recombinamer functionalized with an antimicrobial domain". Paper presented in MicroBiotec¿15, 2015.
  44. Machado, Raul; Silva, A. M.; da Costa, André; Gomes, Andreia Castro; Rodríguez-Cabello, José Carlos; Lanceros-Méndez, Senentxu; Sencadas, Vitor; Casal, Margarida. "Fabrication of antimicrobial composite materials comprising a genetically engineered copolymer". Paper presented in MICROBIOTEC ¿15, 2015.
  45. da Costa, André; Machado, Raul; Sencadas, Vitor; Lanceros-Méndez, Senentxu; Gomes, Andreia Castro; Rodríguez-Cabello, José Carlos; Casal, Margarida. "Antimicrobial electrospun fibres of an elastin-like recombinamer functionalized with an antimicrobial domain". Paper presented in MICROBIOTEC ¿15, 2015.
  46. Barroca, Mário; Rodrigues, Paulo; Branca, Fernando; Casal, Margarida; Collins, Tony. "Reducing Acetate Accumulation and Plasmid Instability for Enhanced Recombinant Protein Production in E. coli". Paper presented in III Symposium PDBMA, Braga, Portugal, 2015.
  47. Pereira, Ana Margarida; Viana, J. F. C.; da Costa, André; Machado, Raul; Ferreira, A. C. R.; Casal, Margarida; Franco, O. L.; Dias, Simoni Campos. "Heterologous expression of antimicrobial peptide synoeca-mp fused to recombinant protein-based polymer as platform for biomaterials". Paper presented in 23rd International Congress of the International Union for Biochemistry and Molecular Biology (IUBMB) and 44th Annual Meeting of the Brazilian Society for Biochemistry and Molecular Biology, 2015.
  48. Pereira, A.M.; Machado, R.; Bernardo, T.C.; da Costa, André; Ribeiro, A.; Collins, T.; Gomes, A.C.; et al. "Silk-based polymers functionalized with fibronectin type-II for improved cell adhesion". Paper presented in XXXIX Jornadas Portuguesas de Genética, 2015.
  49. Machado, Raul; Silva, A. M.; da Costa, André; Gomes, Andreia Castro; Rodríguez-Cabello, José Carlos; Lanceros-Méndez, Senentxu; Sencadas, Vitor; Casal, Margarida. "Antibacterial activity of genetically engineered silk-elastin-like films and fibres containing silver nanoparticles". Paper presented in XXXIX Jornadas Portuguesas de Genética, 2015.
  50. Campos, A. R.; Oliveira, B.; Machado, Raul; Collins, Tony; Azevedo-Silva, João; da Costa, André; Immonen, K.; Wikstrom, L.; Casal, Margarida. "Nanocellulose composites using a recombinant protein based polymer as matrix.". Paper presented in International Conference on Natural Fibers (ICNF2015), Sao Miguel, Azores, Portugal,, 2015.
  51. Barroca, Mário; Rodrigues, Paulo; Branca, Fernando; Casal, Margarida; Collins, Tony. "High-level biosynthesis of a silk-elastin-like protein in E. coli: reducing acetate accumulation and plasmid instability.". Paper presented in XVIII Congress of the Portuguese Biochemical Society (SPB), Coimbra, Portugal, 2014.
  52. Chitas, Rute; Ribeiro, Artur; Gomes, Andreia C.; Casal, Margarida; Machado, Raul. "A molecular biotechnological approach for the development of Silk-Elastin-Like Proteins functionalized with Leukemia Inhibitory Factor". Paper presented in II Symposium of the PhD Programme on Molecular and Environmental Biology, 2014.
  53. Pereira, A.M.; Machado, R.; da Costa, André; Ribeiro, A.; Collins, T.; Gomes, A.C.; Leonor, I.B.; Reis, R.L.; Casal, Margarida. "Functionalized silk-based polymers as advanced biomaterials". Paper presented in II Symposium of the PDBMA, 2014.
  54. Silva, A.M.; da Costa, André; Chitas, R.; Collins, T.; Gomes, A.C.; Rodriguez-Cabello, J.C.; Lanceros-Méndez, S.; et al. "Fabrication of SELP/Ag nanocomposite materials with antimicrobial properties by electrospinning and solvent casting". Paper presented in International Conference on Antimicrobial Research (ICAR 2014), 2014.
  55. Machado, R.; da Costa, André; Sencadas, V.; Gomes, A.C.; Lanceros-Méndez, S.; Rodriguez-Cabello, J.C.; Casal, Margarida. "Electrospun silk-elastin-like fiber mats with potential application for tissue engineering". Paper presented in Electrospinning, Principles, Possibilities and Practice 2013, 2013.
  56. Mota, Sandra; Vieira, Neide; Devaux, Frédéric; Barbosa, Sónia; Garcia, Mathilde; Lemoine, Sophie; Coulpier, Fanny; et al. "Transcriptional and post-transcriptional regulation of yeast lactate and acetate transporters by a RNA helicase". Paper presented in MICROBIOTEC¿13, 2013.
  57. Machado, R.; da Costa, André; Sencadas, V.; Gomes, A.C.; Lanceros-Méndez, S.; Rodriguez-Cabello, J.C.; Casal, Margarida. "Fabrication of recombinant silk-elastin-like fiber mats for tissue engineering applications". Paper presented in Materials Today Virtual Conference: Biomaterials - http://www.materialstoday.com/virtualconference/materials-today-virtual-conference-biomaterials-2013, 2013.
  58. da Costa, André; Machado, R.; Ribeiro, A.; Gomes, A.C.; Rodriguez-Cabello, J.C.; Casal, Margarida. "Development of functionalized recombinant protein-based polymers exhibiting antimicrobial properties". Paper presented in Materials Today Virtual Conference: Biomaterials - http://www.materialstoday.com/virtualconference/materials-today-virtual-conference-biomaterials-2013, 2013.
  59. Machado, R.; da Costa, André; Sencadas, V.; Gomes, A.C.; Lanceros-Méndez, S.; Rodriguez-Cabello, J.C.; Casal, Margarida. "Electrospun silk-elastin-like fibre matrices for tissue engineering applications". Paper presented in ESBP 2013, 2013.
  60. Vieira, Neide; Mota, Sandra; Devaux, Frédéric; Barbosa, Sónia; Garcia, Mathilde; Lemoine, Sophie; Coulpier, Fanny; et al. "The RNA helicase Dhh1 as a regulator of monocarboxylic acids transporters expression in yeast". Paper presented in SMYTE30 (Small Meeting in Yeast Transport and Energetics), Salamanca, Spain, 2012.
  61. Becuwe, Michel; Vieira, Neide; Lara, David; Gomes-Rezende, Jéssica; Soares-Cunha, Carina; Casal, Margarida; Haguenauer-Tsapis, Rosine; et al. "A molecular switch on a yeast arrestin-like protein connects glucose signalling to ubiquitin-dependent transporter endocytosis". Paper presented in Gordon Research Conference on Lysosomes & Endocytosis, Andover, USA, 2012.
  62. Valente D; Pinheiro C; Baltazar, F; Casal, Margarida; Moreira R; Queirós O. "Molecular mechanisms underlying multidrug resistance in cancer cell lines: targeting cell metabolism and pH regulation". Paper presented in XXI Porto Cancer Meeting, abril 2012, Porto, Portugal., 2012.
  63. Pacheco A; Queirós O; Preto A; Pinheiro C; Azevedo-Silva J; Moreira R; Pedro M; Baltazar, F; Casal, Margarida. "Butyric acid increases monocarboxylate transportes (MCT) expression and enhances the cytotoxicity of the anti-tumoral agent 3-bromopyruvate (3-BP) in breast cancer cells.". Paper presented in XXI Porto Cancer Meeting, abril 2012, Porto, Portugal., 2012.
  64. Pacheco A; Queirós, O; Preto A; Pinheiro C; Azevedo-Silva J; Moreira R; Pedro M; Baltazar, F; Casal, Margarida. "3-bromopyruvate cytotoxic effect in breast cancer cells is dependent of monocarboxylate transporters (MCT) expression and is enhanced by butyrate". Paper presented in Metabolism 2012. From signaling to disease, 2012, Heidelberg, Germany., 2012.
  65. Vieira, João Daniel de Almeida; Soares-Silva, Isabel; Ribas, David; Azevedo-Silva, João; Casal, Margarida; Soares, Pedro. "A tool for the extraction of relevant and representative homologues of a given gene: the example of a transmembrane protein from Eukaryotic and Prokaryotic genomes". Paper presented in IJUP - 5th Meeting of Young Researchers of University of Porto, 2012.
  66. Talaia, Gabriel; Diallinas, George; Casal, Margarida; Paiva, Sandra. "Pinpointing intracelllar trafficking determinants in the Jen1 yeast lactate transporter by domain swap.". Paper presented in MicroBiotec11 Congress. Braga, Portugal, 2011.
  67. Collins, T.; Azevedo-Silva, J.; da Costa, André; Machado, R.; Rodriguez-Cabello, J.C.; Casal, Margarida. "Key stress factors and parameters for bath production optimisation of silk-elastin-like proteins in E. coli". Paper presented in Microbiotec¿11, 2011.
  68. Strachotová, Dita; Paiva, Sandra; Casal, Margarida; Váchová, Libu¿e; Palková, Zdena. "Jen1p mediated lactate transport in yeast colony development". Paper presented in 26th Small Meeting on Yeast Transport and Energetics, SMYTE26, Braga, Portugal, 2008.
  69. Vieira, Neide; Casal, Margarida; Johansson, Björn; Brown, Alistair J.; Paiva, Sandra. "Assessing the role of CaJEN2 dicarboxylate permease in fungal virulence.". Paper presented in Yeast Genetics and Molecular Biology Meeting. Toronto, Canada, 2008.
  70. Paiva, Sandra; Urban-Grimal, Danièle; Haguenauer-Tsapis, Rosine; Casal, Margarida. "Glucose-regulated ubiquitylation of the Jen1 permease of Saccharomyces cerevisiae.". Paper presented in Yeast Genetics and Molecular Biology Meeting. Princeton University, USA, 2006.
  71. Barbosa, Sónia; Paiva, Sandra; Casal, Margarida. "The transcription of the monocarboxylic acid transporters JEN1 and ADY2 is downregulated by the gene DHH1 in Saccharomyces cerevisiae". Paper presented in Yeast Genetics and Molecular Biology Meeting. University of Washington, Seattle, USA, 2004.
  72. Queirós, Odília; Paiva, Sandra; Moradas-Ferreira, Pedro; Casal, Margarida. "Molecular and physiological characterization of monocarboxylic acids permeases in the yeast Kluyveromyces lactis.". Paper presented in XXI International Conference on Yeast Genetics and Molecular Biology. Göteborg, Sweden, 2003.
  73. Paiva, Sandra; Kruckeberg, Arthur L.; Casal, Margarida. "Catabolite inactivation of the lactate transporter in Saccharomyces cerevisiae: ubiquitination, endocytosis and degradation in the vacuole.". Paper presented in XX International Conference on Yeast Genetics and Molecular Biology. Prague, Czech Republic, 2001.
  74. Paiva, Sandra; Casal, Margarida; Kruckeberg, Arthur L.; van Dam, Karel; Leão, Cecília. "Functional expression, quantitation and cellular localization of the Jen1 lactate transporter of Saccharomyces cerevisiae tagged with the green fluorescent protein.". Paper presented in Gordon Research Conference "Membrane Transport Proteins". Connecticut College, USA, 2000.
  75. Casal, Margarida; Paiva, Sandra; Andrade, Raquel P.; Leão, Cecília. "Genetic and functional analysis of the Saccharomyces cerevisiae gene JEN1 encoding the lactate permease.". Paper presented in XIX International Conference on Yeast Genetics and Molecular Biology. Rimini, Italy, 1999.
  76. Schuller, Dorit; Andrade, Raquel P.; Paiva, Sandra; Queirós, Odília; Casal, Margarida; Moradas-Ferreira, Pedro; Leão, Cecília. "Cloning of the genes involved on the lactate, acetate and malate transport in the yeasts Saccharomyces cerevisiae and Kluyveromyces. sp.". Paper presented in MICRO´99, Luso, Portugal, 1999.
  77. Casal, Margarida; Paiva, Sandra; Leão, Cecília. "JEN1, a gene coding for a monocarboxylate transporter in Saccharomyces cerevisiae.". Paper presented in XI Congresso Nacional de Bioquímica, Tomar, Portugal, 1998.
Edited book
  1. Mendes, Adélio; Onofre, António; Tavares, Carlos; Serrão, Ester; Granja, Helena; Maia, Hernâni L. S.; Marcos, João Carlos; et al, ed. conversas com Ciência - Tertúlias FNACiência. Braga, Portugal: Comissão de Interação com a Sociedade da Escola de Ciências da Universidade do Minho. 2012.
    Published
Journal article
  1. Cláudia Barata-Antunes; Marieke Warmerdam; Erik de Hulster; Inês P. Ribeiro; Clara Cardoso; Beatriz Leite; Margarida Casal; et al. "Endocytosis of the Saccharomyces cerevisiae Jen1 monocarboxylate-proton symporter under mildly alkaline conditions: a mechanism to prevent metabolite loss?". Microbial Cell Factories (2026): https://doi.org/10.1186/s12934-026-02955-6.
    10.1186/s12934-026-02955-6
  2. Gomes-Gonçalves, Alexandra; Van Genechten, Wouter; Ataíde, Patrícia; Barata-Antunes, Cláudia; Ghasemi, Faezeh; Casal, Margarida; Teixeira, Miguel C.; et al. "Lactic Acid Influences Iron Assimilation by a Fungal Pathogen via the Iron Reductive Uptake Pathway". MicrobiologyOpen 14 6 (2025): https://doi.org/10.1002/mbo3.70167.
    10.1002/mbo3.70167
  3. Alves, Rosana; Ghasemi, Faezeh; Van Genechten, Wouter; Wijnants, Stefanie; Van Goethem, Odessa; Barata-Antunes, Cláudia; Fernandes, Vitor; et al. "The <i>ATO</i> gene family governs <i>Candida albicans</i> colonization in the dysbiotic gastrointestinal tract". mBio 16 10 (2025): https://doi.org/10.1128/mbio.01644-25.
    10.1128/mbio.01644-25
  4. Pereira-Vieira, Joana; Granja, Sara; Sónia Pires Celeiro; Barbosa-Matos, Catarina; Preto, Ana; Queirós, Odília; Ko, Young Hee; Casal, Margarida; Baltazar, Fátima. "3-Bromopyruvate boosts the effect of chemotherapy in acute myeloid leukemia by a pro-oxidant mechanism". Free Radical Biology and Medicine 234 (2025): 192-202. https://doi.org/10.1016/j.freeradbiomed.2025.04.017.
    10.1016/j.freeradbiomed.2025.04.017
  5. Joana Pereira-Vieira; Daniela D. Weber; Sâmia Silva; Catarina Barbosa-Matos; Sara Granja; Rui Manuel Reis; Odília Queirós; et al. "Glucose Metabolism as a Potential Therapeutic Target in Cytarabine-Resistant Acute Myeloid Leukemia". Pharmaceutics (2024): https://doi.org/10.3390/pharmaceutics16040442.
    10.3390/pharmaceutics16040442
  6. Rendulic, Toni; Perpelea, Andreea; Ortiz, Juan Paulo Ragas; Casal, Margarida; Nevoigt, Elke. Corresponding author: Casal, Margarida. "Mitochondrial membrane transporters as attractive targets for the fermentative production of succinic acid from glycerol in <i>Saccharomyces cerevisiae</i>". FEMS Yeast Research 24 (2024): https://doi.org/10.1093/femsyr/foae009.
    10.1093/femsyr/foae009
  7. Costa-Barbosa, Augusto; Ferreira, Diogo; Pacheco, Maria Inês; Casal, Margarida; Duarte, Henrique Oliveira; Gomes, Catarina; Barbosa, Ana Margarida; et al. "<i>Candida albicans</i> chitinase 3 with potential as a vaccine antigen: production, purification, and characterisation". Biotechnology Journal 19 1 (2023): http://dx.doi.org/10.1002/biot.202300219.
    10.1002/biot.202300219
  8. J. Alves; M. Sousa-Silva; P. Soares; M. Sauer; M. Casal; I. Soares-Silva; Alves, J.; et al. "Structural characterization of the Aspergillus niger citrate transporter CexA uncovers the role of key residues S75, R192 and Q196". Computational and Structural Biotechnology Journal 21 (2023): 2884-2898. http://dx.doi.org/10.1016/j.csbj.2023.04.025.
    Open access • 10.1016/j.csbj.2023.04.025
  9. Margarida Casal; Azevedo-Silva, J.; D. Tavares-Valente; A. Almeida; O. Queirós; F. Baltazar; Y. H. Ko; et al. "Cytoskeleton disruption by the metabolic inhibitor 3-bromopyruvate: implications in cancer therapy". Medical Oncology 39 9 (2022): http://dx.doi.org/10.1007/s12032-022-01712-0.
    10.1007/s12032-022-01712-0
  10. Toni Rendulic; Frederico Mendonça Bahia; Isabel Soares-Silva; Elke Nevoigt; Margarida Casal. "The Dicarboxylate Transporters from the AceTr Family and Dct-02 Oppositely Affect Succinic Acid Production in S. cerevisiae". Journal of Fungi (2022): https://doi.org/10.3390/jof8080822.
    10.3390/jof8080822
  11. "Interactions of cytosolic tails in the Jen1 carboxylate transporter are critical for trafficking and transport activity". Journal of Cell Science 135 10 (2022): http://dx.doi.org/10.1242/jcs.260059.
    10.1242/jcs.260059
  12. Gomes DS; da Costa A; Pereira AM; Casal M; Machado R. "Biocomposites of Silk-Elastin and Essential Oil from <i>Mentha piperita</i> Display Antibacterial Activity.". ACS omega (2022): http://europepmc.org/abstract/med/35252653.
    10.1021/acsomega.1c05704
  13. Maria Sousa-Silva; Pedro Soares; João Alves; Daniel Vieira; Margarida Casal; Isabel Soares-Silva. "Uncovering Novel Plasma Membrane Carboxylate Transporters in the Yeast Cyberlindnera jadinii". Journal of Fungi (2022): https://doi.org/10.3390/jof8010051.
    10.3390/jof8010051
  14. "Evolutionary engineering reveals amino acid substitutions in Ato2 and Ato3 that allow improved growth of Saccharomyces cerevisiae on lactic acid". FEMS Yeast Research 21 4 (2021): http://dx.doi.org/10.1093/femsyr/foab033.
    10.1093/femsyr/foab033
  15. da Costa, André; Pereira, Ana M.; Sampaio, Paula; Rodríguez-Cabello, José Carlos; Gomes, Andreia C.; Casal, Margarida; Machado, Raul. "Protein-Based Films Functionalized with a Truncated Antimicrobial Peptide Sequence Display Broad Antimicrobial Activity". ACS Biomaterials Science & Engineering 7 2 (2021): 451-461. http://dx.doi.org/10.1021/acsbiomaterials.0c01262.
    Open access • Published • 10.1021/acsbiomaterials.0c01262
  16. Sousa-Silva, Maria; Vieira, Daniel; Soares, Pedro; Casal, Margarida; Soares-Silva, Isabel. "Expanding the Knowledge on the Skillful Yeast Cyberlindnera jadinii". Journal of Fungi 7 1 (2021): 36. http://dx.doi.org/10.3390/jof7010036.
    Open access • Published • 10.3390/jof7010036
  17. Rendulic, Toni; Alves, João; Azevedo-Silva, João; Soares-Silva, Isabel; Casal, Margarida. "New insights into the acetate uptake transporter (AceTr) family: Unveiling amino acid residues critical for specificity and activity". (2021): http://hdl.handle.net/1822/75506.
    10.1016/j.csbj.2021.08.002
  18. Pereira, Ana Margarida; da Costa, André; Dias, Simoni Campos; Casal, Margarida; Machado, Raul. "Production and purification of two bioactive antimicrobial peptides using a two-step approach involving an elastin-like fusion tag". (2021): http://hdl.handle.net/1822/75785.
    10.3390/ph14100956
  19. Barata-Antunes, Cláudia; Alves, R.; Talaia, Gabriel; Casal, Margarida; Gerós, H.; Mans, Robert; Paiva, Sandra. "Endocytosis of nutrient transporters in fungi: the ART of connecting signaling and trafficking". (2021): http://hdl.handle.net/1822/72047.
    10.1016/j.csbj.2021.03.013
  20. Pereira, Ana Margarida Macedo Bernardes; Gomes, Diana Cristina Serra; da Costa, André; Dias, Simoni Campos; Casal, Margarida; Machado, Raul. "Protein-engineered polymers functionalized with antimicrobial peptides for the development of active surfaces". (2021): https://hdl.handle.net/1822/74226.
    10.3390/app11125352
  21. Becerra-Rodríguez, Carmen; Taghouti, Géraldine; Portier, Perrine; Dequin, Sylvie; Casal, Margarida; Paiva, Sandra; Galeote, Virginie; et al. "Yeast plasma membrane Fungal Oligopeptide Transporters display distinct substrate preferences despite their high sequence identity". Journal of Fungi 7 11 (2021): 963-963. https://hdl.handle.net/1822/76480.
    10.3390/jof7110963
  22. Margarida Paula Pedra Amorim Casal; Alves, Rosana; Barata-Antunes, Claudia; Casal, Margarida; Brown, Alistair J. P.; Van Dijck, Patrick; Paiva, Sandra. "Adapting to survive: How Candida overcomes host-imposed constraints during human colonization". PLOS Pathogens (2020): http://dx.doi.org/10.1371/journal.ppat.1008478.
    10.1371/journal.ppat.1008478
  23. Gomes, Sara Daniela; Oliveira, Claudia Suellen; Azevedo-Silva, João; Casanova, Marta Alexandra Rodrigues; Barreto, Judite; Pereira, Helena; Chaves, Susana; et al. "The role of diet related short-chain fatty acids in colorectal cancer metabolism and survival: prevention and therapeutic implications". Current Medicinal Chemistry 25 (2020): http://hdl.handle.net/1822/58525.
    Published • 10.2174/0929867325666180530102050
  24. Alves, R.; Kastora, Stavroula L.; Gomes-Gonçalves, Alexandra; Azevedo, Nuno Miguel Morais; Rodrigues, Célia F.; Silva, Sónia Carina; Demuyser, Liesbeth; et al. "Transcriptional responses of Candida glabrata biofilm cells to fluconazole are modulated by the carbon source". npj Biofilms and Microbiomes 6 1 (2020): http://hdl.handle.net/1822/65601.
    Published • 10.1038/s41522-020-0114-5
  25. Soares-Silva, Isabel João; Ribas, D.; Sousa-Silva, M.; Azevedo-Silva, J.; Rendulic, T.; Casal, Margarida; I Soares-Silva; et al. "Membrane transporters in the bioproduction of organic acids: state of the art and future perspectives for industrial applications". FEMS Microbiology Letters (2020): https://hdl.handle.net/1822/72964.
    Accepted • 10.1093/femsle/fnaa118
  26. Alves, Rosana; Sousa-Silva, M.; Vieira, Daniel; Soares, Pedro; Chebaro, Yasmin; Lorenz, Michael C.; Casal, Margarida; et al. "Carboxylic acid transporters in Candida pathogenesis". mBio. Accepted 11 3 (2020): https://hdl.handle.net/1822/72875.
    Accepted • 10.1128/mBio.00156-20
  27. Correia, Daniela M.; Ribeiro, S.; Costa, André da; Ribeiro, Clarisse; Casal, Margarida; Lanceros-Méndez, S.; Machado, Raul; et al. "Development of bio-hybrid piezoresistive nanocomposites using silk-elastin protein copolymers". Composites Science and Technology 172 (2019): 134-142. http://hdl.handle.net/1822/58896.
    10.1016/j.compscitech.2019.01.017
  28. Pereira-Vieira, Joana; Azevedo-Silva, Joao; Preto, Ana; Casal, Margarida; Queiros, Odilia; Pereira-Vieira, J.; Azevedo-Silva, J.; et al. "MCT1, MCT4 and CD147 expression and 3-bromopyruvate toxicity in colorectal cancer cells are modulated by the extracellular conditions". Biological Chemistry (2019): http://hdl.handle.net/1822/72947.
    10.1515/hsz-2018-0411
  29. Ribas, David; Soares-Silva, Isabel; Vieira, Daniel; Sousa-Silva, M.; Sa-Pessoa, Joana; Azevedo-Silva, Joao; Viegas, Sandra Cristina; et al. "The acetate uptake transporter family motif "NPAPLGL(M/S)" is essential for substrate uptake". Fungal Genetics and Biology 122 (2019): 1-10. https://hdl.handle.net/1822/72900.
    10.1016/j.fgb.2018.10.001
  30. Ko, Young H.; Niedzwiecka, Katarzyna; Casal, Margarida; Pedersen, Peter L.; Ulaszewski, Stanislaw. "3-Bromopyruvate as a potent anticancer therapy in honor and memory of the late Professor Andre Goffeau". Yeast 36 4 (2019): 211-221. http://hdl.handle.net/1822/72960.
    Published • 10.1002/yea.3367
  31. Niedzwiecka, Katarzyna; Ribas, David; Casal, Margarida; Ulaszewski, Stanislaw; Niedzwiecka K; Ribas D; Casal M; Ulaszewski S. "The Cryptococcus neoformans monocarboxylate transporter Jen4 is responsible for increased 3-bromopyruvate sensitivity". (2019): http://hdl.handle.net/1822/73112.
    10.1093/femsyr/foz029
  32. Machado, R.; da Costa, A.; Silva, D.M.; Gomes, A.C.; Casal, M.; Sencadas, V.. "Antibacterial and Antifungal Activity of Poly(Lactic Acid)–Bovine Lactoferrin Nanofiber Membranes". Macromolecular Bioscience 18 3 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85040675171&partnerID=MN8TOARS.
    10.1002/mabi.201700324
  33. da Costa, A.; Pereira, Ana Margarida Macedo Bernardes; Gomes, Andreia C; Rodriguez-Cabello, J. C.; Casal, Margarida; Machado, Raul; Pereira, A.M.; et al. "Production of bioactive hepcidin by recombinant DNA tagging with an elastin-like recombinamer". New Biotechnology 46 (2018): 45-53. http://hdl.handle.net/1822/72889.
    Published • 10.1016/j.nbt.2018.07.001
  34. Fernandes, Margarida; Correia, D. M.; Costa, A. da; Ribeiro, S.; Casal, M.; Lanceros-Méndez, S.; Machado, R.; et al. "Multifunctional magnetically responsive biocomposites based on genetically engineered silk-elastin-like protein". Composites Part B: Engineering 153 (2018): 413-419. http://hdl.handle.net/1822/56387.
    10.1016/j.compositesb.2018.09.019
  35. Pereira, A.M.; Machado, R.; da Costa, A.; Ribeiro, A.; Collins, T.; Gomes, A.C.; Leonor, I.B.; et al. "Silk-based biomaterials functionalized with fibronectin type II promotes cell adhesion". Acta Biomaterialia 47 (2017): 50-59. http://www.scopus.com/inward/record.url?eid=2-s2.0-84995494159&partnerID=MN8TOARS.
    10.1016/j.actbio.2016.10.002
  36. Ribas, D.; Sá-Pessoa, J.; Soares-Silva, I.; Paiva, S.; Nygård, Y.; Ruohonen, L.; Penttilä, M.; et al. "Yeast as a tool to express sugar acid transporters with biotechnological interest". FEMS Yeast Research 17 2 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85019698072&partnerID=MN8TOARS.
    10.1093/femsyr/fox005
  37. Costa, André Manuel Abreu; Pereira, Ana Margarida Macedo Bernardes; Gomes, Andreia; Rodríguez-Cabello, José Carlos; Sencadas, Vítor João Gomes Silva; Casal, Margarida; Machado, Raul; et al. "Single step fabrication of antimicrobial fibre mats from a bioengineered protein-based polymer". Biomedical Materials (Bristol) 12 4 (2017): http://hdl.handle.net/1822/47690.
    10.1088/1748-605X/aa7104
  38. Talaia, Gabriel; Gournas, Christos; Saliba, Elie; Barata-Antunes, Cláudia; Casal, Margarida; André, Bruno; Diallinas, George; et al. "The a-Arrestin Bul1p Mediates Lactate Transporter Endocytosis in Response to Alkalinization and Distinct Physiological Signals". Journal of Molecular Biology 429 23 (2017): 3678-3695. http://hdl.handle.net/1822/50889.
    10.1016/j.jmb.2017.09.014
  39. Alves, R.; Mota, Sandra; Silva, Sónia Carina; Rodrigues, Célia F.; Brown, Alistair J.; Henriques, Mariana; Casal, Margarida; et al. "The carboxylic acid transporters Jen1 and Jen2 affect the architecture and fluconazole susceptibility of Candida albicans biofilm in the presence of lactate". Biofouling 33 10 (2017): 943-954. http://hdl.handle.net/1822/48442.
    10.1080/08927014.2017.1392514
  40. Azevedo-Silva, J.; Queirós, O.; Baltazar, F.; Ulaszewski, S.; Goffeau, A.; Ko, Y.H.; Pedersen, P.L.; et al. "The anticancer agent 3-bromopyruvate: a simple but powerful molecule taken from the lab to the bedside". Journal of Bioenergetics and Biomembranes 48 4 (2016): 349-362. http://www.scopus.com/inward/record.url?eid=2-s2.0-84979641440&partnerID=MN8TOARS.
    10.1007/s10863-016-9670-z
  41. Ferro, Suellen; Azevedo-Silva, João; Casal, Margarida; Côrte-Real, Manuela; Baltazar, Fátima; Preto, Ana; Ferro, S.; et al. "Characterization of acetate transport in colorectal cancer cells and potential therapeutic implications". Oncotarget 7 43 (2016): 70639-70653. http://hdl.handle.net/1822/48145.
    10.18632/oncotarget.12156
  42. Barroca, Mário Jorge Faria; Rodrigues, Paulo; Sobral, Rómulo Sacramento; Costa, Maria Manuela Ribeiro; Chaves, Susana R.; Machado, Raul; Casal, Margarida; et al. "Antibiotic free selection for the high level biosynthesis of a silk-elastin-like protein". Scientific Reports 6 (2016): http://hdl.handle.net/1822/45777.
    10.1038/srep39329
  43. Mota, S.; Alves, R.; Carneiro, C.; Silva, S.; Brown, A.J.; Istel, F.; Kuchler, K.; et al. "Candida glabrata susceptibility to antifungals and phagocytosis is modulated by acetate". Frontiers in Microbiology 6 SEP (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84946741757&partnerID=MN8TOARS.
    Published • 10.3389/fmicb.2015.00919
  44. Padrão, Jorge; Machado, Raul; Casal, Margarida; Lanceros-Méndez, S.; Rodrigues, L. R.; Dourado, Fernando; Sencadas, V.; et al. "Antibacterial performance of bovine lactoferrin-fish gelatine electrospun membranes". International Journal of Biological Macromolecules 81 (2015): 608-614. http://hdl.handle.net/1822/37129.
    10.1016/j.ijbiomac.2015.08.047
  45. Machado, Raul; Costa, André da; Sencadas, Vítor João Gomes Silva; Pereira, Ana Margarida Arantes; Collins, Tony; Rodríguez-Cabello, José Carlos; Lanceros-Méndez, S.; et al. "Exploring the properties of genetically engineered silk-elastin-like protein films". Macromolecular Bioscience 15 12 (2015): 1698-1709. http://hdl.handle.net/1822/40689.
    Published • 10.1002/mabi.201500132
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    Published • 10.1016/j.femsyr.2005.04.007
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  117. Ramalho, Patrícia A.; Paiva, Sandra; Paulo, Artur Cavaco; Casal, Margarida; Cardoso, M. Helena; Ramalho, Maria Teresa; Ramalho, P.A.; et al. "Azo reductase activity of intact Saccharomyces cerevisiae cells is dependent on the Fre1p component of plasma membrane ferric reductase". Applied and Environmental Microbiology 71 7 (2005): 3882-3888. http://hdl.handle.net/1822/2587.
    10.1128/AEM.71.7.3882-3888.2005
  118. Paiva, S.; Devaux, F.; Barbosa, S.; Jacq, C.; Casal, M.. "Ady2p is essential for the acetate permease activity in the yeast Saccharomyces cerevisiae". Yeast 21 3 (2004): 201-210. http://www.scopus.com/inward/record.url?eid=2-s2.0-1342290477&partnerID=MN8TOARS.
    10.1002/yea.1056
  119. Soares-Silva, I.; Paiva, S.; Kötter, P.; Entian, K.-D.; Casal, M.; Silva, Isabel Soares; Paiva, Sandra; et al. "The disruption of JEN1 from Candida albicans impairs the transport of lactate". Molecular Membrane Biology 21 6 (2004): 403-411. http://www.scopus.com/inward/record.url?eid=2-s2.0-11144341410&partnerID=MN8TOARS.
    10.1080/09687860400011373
  120. Schuller, Dorit Elisabeth; Valero, Eva; Dequin, Sylvie; Casal, Margarida; Schuller, D.; Valero, E.; Dequin, S.; Casal, M.. "Survey of molecular methods for the typing of wine yeast strains". FEMS Microbiology Letters 231 1 (2004): 19-26. http://hdl.handle.net/1822/2213.
    10.1016/S0378-1097(03)00928-5
  121. Paiva, Sandra; Devaux, Frederic; Barbosa, Sónia; Jacq, Claude; Casal, Margarida. "Ady2p is essential for the acetate permease activity in the yeast Saccharomyces cerevisiae". (2004): http://hdl.handle.net/1822/2935.
    10.1002/yea.1056
  122. Soares-Silva, I.; Schuller, D.; Andrade, R.P.; Baltazar, F.; Cássio, F.; Casal, M.; Silva, Isabel Soares; et al. "Functional expression of the lactate permease Jen1p of Saccharomyces cerevisiae in Pichia pastoris". Biochemical Journal 376 3 (2003): 781-787. http://www.scopus.com/inward/record.url?eid=2-s2.0-0347986613&partnerID=MN8TOARS.
    10.1042/BJ20031180
  123. Paiva, S.; Kruckeberg, A.L.; Casal, M.; Paiva, Sandra; Kruckeberg, Arthur L.; Casal, Margarida. "Utilization of green fluorescent protein as a marker for studying the expression and turnover of the monocarboxylate permease Jen1p of Saccharomyces cerevisiae". Biochemical Journal 363 3 (2002): 737-744. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036566150&partnerID=MN8TOARS.
    10.1042/0264-6021:3630737
  124. Salgado, A. C. P.; Schuller, Dorit Elisabeth; Casal, Margarida; Leão, Cecília; Leiper, F. C.; Carling, D.; Fietto, L. G.; et al. "Relationship between Protein kinase C and derepression of different enzymes". FEBS Letters 532 3 (2002): 324-332. http://hdl.handle.net/1822/2258.
    10.1016/S0014-5793(02)03695-5
  125. Queirós, O.; Casal, M.; Moradas-Ferreira, P.; Leão, C.. "PCR-based method for the construction of gene disruption cassettes in yeast". BioTechniques 31 2 (2001): 264-268. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034880445&partnerID=MN8TOARS.
  126. Makuc, J.; Paiva, S.; Schauen, M.; Krämer, R.; André, B.; Casal, M.; Leo, C.; et al. "The putative monocarboxylate permeases of the yeast Saccharomyces cerevisiae do not transport monocarboxylic acids across the plasma membrane". Yeast 18 12 (2001): 1131-1143. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034834876&partnerID=MN8TOARS.
    10.1002/yea.763
  127. Andrade, R.P.; Casal, M.. "Expression of the lactate permease gene JEN1 from the yeast Saccharomyces cerevisiae". Fungal Genetics and Biology 32 2 (2001): 105-111. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035574192&partnerID=MN8TOARS.
    10.1006/fgbi.2001.1254
  128. Paiva, S.; Althoff, S.; Casal, M.; Leão, C.; Paiva, Sandra; Althoff, Stefanie; Casal, Margarida; Leão, Cecília. "Transport of acetate in mutants of Saccharomyces cerevisiae defective in monocarboxylate permeases". FEMS Microbiology Letters 170 2 (1999): 301-306. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032960160&partnerID=MN8TOARS.
    10.1016/S0378-1097(98)00522-9
  129. Casal, Margarida; Paiva, Sandra; Andrade, Raquel P.; Gancedo, Carlos; Leão, Cecília; Casal, M.; Paiva, S.; et al. "The lactate-proton symport of Saccharomyces cerevisiae is encoded by JEN1". Journal of Bacteriology 181 8 (1999): 2620-2623. https://hdl.handle.net/1822/2971.
    10.1128/JB.181.8.2620-2623.1999
  130. Casal, M.; Cardoso, H.; Leão, C.. "Effects of ethanol and other alkanols on transport of acetic acid in Saccharomyces cerevisiae". Applied and Environmental Microbiology 64 2 (1998): 665-668. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031912520&partnerID=MN8TOARS.
  131. Queiros, O.; Casal, M.; Althoff, S.; Moradas-Ferreira, P.; Leao, C.. "Isolation and characterization of Kluyveromyces marxianus mutants deficient in malate transport". Yeast 14 5 (1998): 401-407. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032579810&partnerID=MN8TOARS.
    10.1002/(SICI)1097-0061(19980330)14:5<401::AID-YEA234>3.0.CO;2-T
  132. Casal, M.; Cardoso, H.; Leão, C.. "Mechanisms regulating the transport of acetic acid in Saccharomyces cerevisiae". Microbiology 142 6 (1996): 1385-1390. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030001104&partnerID=MN8TOARS.
  133. Casal, M.; Leão, C.. "Utilization of short-chain monocarboxylic acids by the yeast Torulaspora delbrueckii: Specificity of the transport systems and their regulation". BBA - Molecular Cell Research 1267 2-3 (1995): 122-130. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029020764&partnerID=MN8TOARS.
    10.1016/0167-4889(95)00067-3
  134. Casal, M.; Blázquez, M.; Gamo, J.; Gancedo, C.; Leao, C.. "Transport of lactate and its regulation in Saccharomyces cerevisiae mutants deficient in specific metabolic steps". Folia Microbiologica: Official Journal of the Institute of Microbiology, Academy of Sciences of the Czech Republic 39 6 (1994): 512-512. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028679720&partnerID=MN8TOARS.
    10.1007/BF02814076
  135. Casal, M.; Leão, C.. "Utilization of acetic acid and other short-chain monocarboxylic acids in the yeasts Torulaspora delbrueckii and Saccharomyces cerevisiae: Transport and its regulation". Folia Microbiologica: Official Journal of the Institute of Microbiology, Academy of Sciences of the Czech Republic 39 6 (1994): 512-513. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028679008&partnerID=MN8TOARS.
    10.1007/BF02814077
Magazine article
  1. Schuller, Dorit Elisabeth; Casal, Margarida. "Utilisation de souches de levures génétiquement modifiées en œnologie", Revista internet de viticultura e enologia, 2006, http://hdl.handle.net/1822/5003.
  2. Schuller, Dorit Elisabeth; Casal, Margarida. "A utilização de estirpes de leveduras geneticamente modificadas em enologia", Revista internet de viticultura e enologia, 2006, http://hdl.handle.net/1822/5084.
  3. Valero, Eva; Schuller, Dorit Elisabeth; Cambon, Brigitte; Casal, Margarida; Dequin, Sylvie. "Uso dei lieviti selezionati e biodiversità", Revista internet de viticultura e enologia, 2006, http://hdl.handle.net/1822/5009.
  4. Schuller, Dorit Elisabeth; Alves, Hugo; Dequin, Sylvie; Casal, Margarida. "Panorama ecólogico de cepas de Saccharomyces cerevisiae en um viñedo dela región Vinho Verde en Portugal", Revista Internet de Viticultura e Enologia, 2005, http://hdl.handle.net/1822/4369.
  5. Schuller, Dorit Elisabeth; Alves, Hugo; Dequin, Sylvie; Casal, Margarida. "Estudo ecológico das estirpes Saccharomyces cerevisiae numa vinha da Região dos Vinhos Verdes em Portugal", Infowine : Revista Internet de Viticultura e Enologia, 2005, http://hdl.handle.net/1822/4387.
  6. Schuller, Dorit Elisabeth; Alves, Hugo; Dequin, Sylvie; Casal, Margarida. "Recensement ecologique des souches de Saccharomyces cerevisiae presentes dans des vignobles de la region du Vinho Verde (Portugal)", Infowine : Revue Internet de Viticulture et Oenologie, 2005, http://hdl.handle.net/1822/4370.
  7. Valero, Eva; Schuller, Dorit Elisabeth; Cambon, Brigitte; Casal, Margarida; Dequin, Sylvie. "Selected yeast utilization and biodiversity", Infowine : Revista Internet de Viticultura e Enologia, 2005, http://hdl.handle.net/1822/6110.
  8. Valero, Eva; Schuller, Dorit Elisabeth; Cambon, Brigitte; Casal, Margarida; Dequin, Sylvie. "Assessment of environmental impact of commercial wine yeast in vineyard ecosystems", Infowine : Revista Internet de Viticultura e Enologia, 2005, http://hdl.handle.net/1822/6078.
  9. Leão, Cecília; Rodrigues, Fernando José dos Santos; Paiva, Sandra; Queirós, Odília; Schuller, Dorit Elisabeth; Cássio, Fernanda; Cardoso, M. Helena; Casal, Margarida; Côrte-Real, Manuela. "Remoção zimológica da acidez volátil e fixa de mostos e vinhos: da fisiologia à manipulação genética de leveduras", Boletim de Biotecnologia, 2000, http://hdl.handle.net/1822/2079.
Manual
  1. Casal, Margarida; Machado, Raul; da Costa, André. Biopolymers from renewable resouces: from synthesis to applications.. Braga, Portugal, Portugal: -. 2020.
    Published
  2. Casal, Margarida; Schuller, Dorit Elisabeth; Ribeiro, Ana; Cardoso, Helena; Nobre, Alexandra. Prospecção de bactérias produtoras de antibióticos. Copissaurio. 2004.
    Published
  3. Schuller, Dorit Elisabeth; Pais, Célia; Casal, Margarida. Métodos moleculares de identificação de leveduras do vinho. 2004.
    Published
  4. Casal, Margarida; Schuller, Dorit Elisabeth; Rodrigues, Georgina Maria Martins; Pais, Célia. Métodos convencionais em microbiologia. 2004.
    Published
Newsletter article
  1. Leão, Cecília; Rodrigues, Fernando José dos Santos; Paiva, Sandra; Queirós, Odília; Schuller, Dorit; Cássio, Fernanda; Cardoso, M. Helena; Casal, Margarida; Côrte-Real, Manuela. "Remoção Zimológica da acidez volátil e fixa de mostos e vinhos: da fisiologia à manipulação genética de leveduras.", Boletim de Biotecnologia, 2000
Newspaper article
  1. Margarida Paula Pedra Amorim Casal. "A quem pertencem os nossos genes", Correio do Minho, 2016, https://www.ecum.uminho.pt/pt/Media/Documents/Correio%20do%20Minho/2015/06-02-2015.pdf.
Preprint
  1. Ghasemi, Faezeh; Ataíde, Patrícia; Barata-Antunes, Cláudia; Pyrris, Yiannis; Alves, João; Fernandes, Vitor; Alves, Rosana; et al. "Expansion, Functional Diversification, and Gene Fusion Events in the Ato Protein Family". 2026.
  2. Schuller, Dorit Elisabeth; Casal, Margarida. "The genetic structure of fermentative vineyard-associated Saccharomyces cerevisiae populations revealed by microsatellite analysis". 2007. https://hdl.handle.net/1822/6486.
  3. Ramalho, Patrícia A.; Paiva, Sandra; Paulo, Artur Cavaco; Casal, Margarida; Cardoso, M. Helena; Ramalho, Maria Teresa. "Role of the component Fre1p of the plasma membrane ferric reductase on the azo reductase activity of intact Saccharomyces cerevisiae cells". 2005. http://hdl.handle.net/1822/2326.
Thesis / Dissertation
  1. Vieira, Joana Margarida Pereira. "Exploration of glucose metabolism in acute myeloid leukemia: effect of 3-bromopyruvate in the response to chemotherapy". PhD, 2025. https://hdl.handle.net/1822/98503.
  2. Alves, João Fernando Machado. "Yeast as a model system for the study of carboxylic acid transporters". PhD, 2024. https://hdl.handle.net/1822/95054.
  3. Rendulic, Toni. "Engineering plasma membrane transporters to improve organic acid production". PhD, 2023. https://hdl.handle.net/1822/87077.
  4. Sousa-Silva, M.. "Identification and functional characterization of novel plasma membrane carboxylate transporters". PhD, 2021. https://hdl.handle.net/1822/75606.
  5. Pereira, Ana Margarida Macedo Bernardes. "Insights into the mechanism of antimicrobial activity and its exploitation for developing new therapies against clinically relevant bacteria". PhD, 2021. http://hdl.handle.net/1822/77298.
  6. Alves, Rosana Maria Abreu. "Function and regulation of Candida albicans and C. glabrata carboxylic acid transporters and their Role in biofilm formation, antifungal drug resistance and phagocytosis". PhD, 2020. https://hdl.handle.net/1822/75984.
  7. Rocha, Gabriel Azevedo Carreira Talaia da. "Endocytic trafficking and ubiquitylation of plasma membrane transporters in yeast". PhD, 2019. http://hdl.handle.net/1822/60239.
  8. Vieira, Maria Eugénia Gonçalves. "Novos produtos biotecnológicos e serviços para a indústria dos vinhos". PhD, 2019. http://hdl.handle.net/1822/60642.
  9. Ribas, David Manuel Nogueira. "Characterization of carboxylate transporters: functional and structural studies for the improvement of cell factories". PhD, 2018. https://hdl.handle.net/1822/59022.
  10. Gomes, Diana Cristina Serra. "Formulation of biocomposites based on recombinant proteins and plant essential oils for the development of active wound dressings". Master, 2017. http://hdl.handle.net/1822/50068.
  11. Vieira, Joana Margarida Pereira. "Molecular mechanisms involved in 3- bromopyruvate effect in colorectal cancer cell lines". Master, 2017. https://hdl.handle.net/1822/54803.
  12. Almeida, Ana Carolina Gomes. "Functional expression of transporters in yeast". Master, 2017. http://hdl.handle.net/1822/64829.
  13. Barbosa, Ana Margarida Oliveira. "Unravelling the molecular mechanismsunderlying 3-bromopyruvate resistance in tumor cell lines". Master, 2016. http://hdl.handle.net/20.500.11816/2541.
  14. Casal, Margarida; Gomes, Andreia; Cabello, José Carlos Rodríguez; Costa, André Manuel Abreu da. "Functionalization of protein-based polymers for advanced biomaterials". PhD, 2016. http://hdl.handle.net/1822/42525.
  15. Silva, João Pedro Azevedo. "The role of monocarboxylate transporters in 3-bromopyruvate effect in cancer cells". PhD, 2016. http://hdl.handle.net/1822/41582.
  16. Athayde, Diogo Pinto Pereira de. "Structural studies of succinate acetate transporter and type II NADH dehydrogenase". Master, 2016. https://hdl.handle.net/1822/42936.
  17. Barardo, Diogo Gonçalves. "Creation of databases of ageing-related drugs and statistical analysis and applied machine learning for the prioritization of potential lifespan-extension drugs". Master, 2016. http://hdl.handle.net/1822/42973.
  18. Silva, Andreia Maria Azevedo da. "Production of silk-elastin-like composite materials with antimicrobial properties". Master, 2015. http://hdl.handle.net/1822/35713.
  19. Rodrigues, Paulo Jorge Barbosa. "Fed-batch production of a silk-elastin-like protein: investigating plasmid stabilisation and glycerol as carbon source". Master, 2015. http://hdl.handle.net/1822/37298.
  20. Chitas, Rute Malarranha. "A molecular biotechnological approach for the development of silk-elastin-like proteins functionalized with leukemia inhibitory factor". Master, 2014. http://hdl.handle.net/1822/34651.
  21. Mota, Sandra Marlene da Silva. "Study of the mechanisms of transport and regulation of carboxylic acids in Candida albicans and Candida glabrata". PhD, 2014. http://hdl.handle.net/1822/35502.
  22. Ribeiro, Ana Luísa Ferreira. "3-Bromopyruvate as an anticancer agent in breast cancer cell lines: exploring the role of monocarboxylate transporters". Master, 2013. http://hdl.handle.net/1822/27922.
  23. Ferreira, Catherine Oliveira. "Thiol-disulphide oxidoreductases : production, purification and structural analysis of a cold adapted DsbA". Master, 2013. http://hdl.handle.net/1822/25520.
  24. Santos, Joana Margarida Sá Pessoa da Graça. "Structural-functional studies of plasma membrane carboxylate transporters in yeast". PhD, 2013. http://hdl.handle.net/1822/28839.
  25. Ribas, David Manuel Nogueira. "Structural-functional studies of carboxylic acid transporters : novel tools in production optimization using industrial microbes". Master, 2013. http://hdl.handle.net/1822/28030.
  26. Barroca, Mário Jorge Faria. "Optimisation of the fed-batch production of a silk-elastin-like protein: overcoming acetate accumulation and plasmid instability". Master, 2013. https://hdl.handle.net/1822/27914.
  27. Machado, Raul Miguel Ribeiro. "Design, bioproduction and characterization of protein recombinant silk-elastin-based polymers: a new class of nano-biomaterials". PhD, 2012. http://hdl.handle.net/1822/23177.
  28. Alves,Ana Margarida Fernandes Grácio de Almeida. "I know why the caged bird sings: uma experiência tradutória". Master, 2012. http://hdl.handle.net/10451/6971.
  29. Pereira, Neide Marina Vieira. "The transport of carboxylic acids in yeasts : from physiology towards structural-functional characterization of permeases". PhD, 2010. http://hdl.handle.net/1822/10563.
  30. Costa, André da; Casal, Margarida; Paulo, Artur Cavaco. "Cloning and expression of antimicrobial peptides and their evaluation for biotechnological applications". Master, 2010. http://hdl.handle.net/1822/13360.
  31. Bessa, Paulo C.. "Novel biodegradable drug delivery systems for the controlled release of growth factors in bone healing and tissue engineering". PhD, 2009. http://hdl.handle.net/1822/10265.
  32. Moreira, Susana Margarida Gomes. "Recombinant carbohydrate-binding modules for biomedical applications Biocompatibility of polysaccharide-based materials". PhD, 2009. http://hdl.handle.net/1822/9824.
  33. Catarino, Raquel Jorge Ferreira. "Polimorfismo no gene da Ciclina D1 em neoplasias associadas a vírus". Master, 2005. http://hdl.handle.net/1822/3468.

Intellectual property

Patent
  1. Elke Nevoigt; Rendulic, Toni; Casal, Margarida. 2023. "Patent application submitted (Patent Application 10 2023 114 310.7 - GENTECHNISCH VERÄNDERTE HEFEZELLE / CÉLULA DE LEVEDURA GENETICAMENTE MODIFICADA). Inventors: CASAL, Margarida; NEVOIGT, Elke; RENDULIC, Toni.". Germany.
    Pending
  2. Soares-Silva, Isabel João; Rendulic, Toni; Casal, Margarida. 2023. "Pedido de patente europeia 2022. N.º: EP 22166183.8 - 25.07.2023 - YEAST CELL EXPRESSING A PLASMA MEMBRANE ORGANIC ACID TRANSPORTER, METHODS AND USES. Inventors: PEDRA AMORIM CASAL, Margarida Paula; SOARES DA SILVA, Isabel João; RENDULIC, Toni.". Portugal.
    Pending
  3. I. Soares-Silva; Rendulic, Toni; Casal, Margarida. 2021. "Pedido Provisório de Patente 2021. nº 117253 YEAST CELL EXPRESSING A PLASMA MEMBRANE ORGANIC ACID TRANSPORTER, METHODS AND USES THEREOF Inventors: PEDRA AMORIM CASAL, Margarida Paula; SOARES DA SILVA, Isabel João; RENDULIC, Toni.". Portugal.
  4. Margarida Paula Pedra Amorim Casal. 2020. "A METHOD FOR EXPRESSION OF A PROKARYOTIC MEMBRANE PROTEIN IN AN EUKARYOTIC ORGANISM, PRODUCTS AND USES THEREOF". United States.
  5. Margarida Paula Pedra Amorim Casal; Dorit Schuller; Isabel Maria Morais Araújo; Maria Eugénia GONÇALVES VIEIRA. 2017. "Saccharomyces cerevisiae strain EP2837698B1".
    Granted/Issued
  6. Real Oliveira, M. Elisabete C.D.; Gomes, Andreia; Paulo J. G. Coutinho; Casal, Margarida; Coutinho, Olga; Neves Silva, J.P.. 2012. "Lipofection system for transfecting DNA or RNA into cell lines of mammal used in e.g. molecular biology, comprises nucleic acid, cationic dioctadecyldimethylammonium derived lipid, monoolein lipid and cholesterol or its derivative". Portugal.
    Granted/Issued
  7. Real Oliveira, Maria Elisabete C.D.; Silva, J.P.Neves; Coutinho, P.J.G; Casal, Margarida; Coutinho, Olga M. F. Pereira; Gomes, A.C.. 2011. "Use of Monoolein as a New Auxiliar Lipid in Lipofection".
  8. Margarida Paula Pedra Amorim Casal; Maria Elisabete Cunha Dias Real Oliveira. 2010. "Aplicação da monooleína como novo lípido adjuvante em lipofecção".
    Allowed
  9. Margarida Paula Pedra Amorim Casal; Carla Manuela Pereira Da Silva; RITA ARAÚJO; Paulo, Artur Cavaco; Machado, Raul; Cavaco-Paulo, Artur; Araújo, Rita Isabel Lima; Rodriguez-Cabello, José Carlos; Silva, Carla Manuela Pereira. 2010. "Process for the treatment of animal fibres aimed at improving the shrink-resistance thereof WO2010001356A1".
    Granted/Issued
  10. Real Oliveira, MECD; Neves Silva, J.P.; Coutinho, P.J.G.; Casal, Margarida; Coutinho, O.M.F.P.; Gomes, Andreia C.. 2010. "Use of Monoolein as new auxiliary lipid in lipofection".
  11. Real Oliveira, Maria Elisabete C.D.; Silva Neves, J.P.; Coutinho, P.J.G.; Casal, Margarida; Coutinho, Olga M. F. Pereira; Gomes, Andreia C.. 2008. "Aplicação da monooleina como novo lipído adjuvante em lipofecção".
  12. Domingues, Lucília; Casal, Margarida; Moreira, Susana; Gama, F. M.. 2007. "Modified proteins comprising a bioactive peptide/protein linked to a sequence of aminoacids containing a human carbohydrate binding module (CBM), and development of a system for the administration of therapeutically active proteins and respective utilizations for biomedical purposes".
  13. Margarida Paula Pedra Amorim Casal; FILIPA CARNEIRO, CARLA SILVA; TERESA MATAMÁ; RITA ARAÚJO; GEORG GÜEBITZ; Artur Cavaco Paulo. 2005. "Method for the modification of polyacrylonitrile fibres containing vinyl acetate as a comonomer and polyamide fibres, using a cutinase enzyme".

Other

Other output
  1. Interactions of cytosolic termini of the Jen1 monocarboxylate transporter are critical for trafficking, transport activity and endocytosis. 2021. Barata-Antunes, C.; Talaia, G.; Broutzakis, G.; Ribas, D.; De Beule, P.; Casal, M.; Stefan, C.J.; Diallinas, G.; Paiva, S.. http://www.scopus.com/inward/record.url?eid=2-s2.0-85118615164&partnerID=MN8TOARS.
    10.1101/2021.09.27.461913
  2. Biopolymers based on renewable resources: from synthesis to applications. The course aims at presenting and discussing cutting edge progresses in tailor-made biopolymers – the design, the production, the present and prospective applications. Conscious of the increasing ecological awareness along with new legislation that boosted the demand for products with a high ecological image, both science and industry partners are aiming to develop biopolymers based on renewable r. 2020. Machado, Raul; Casal, Margarida; da Costa, André. http://hdl.handle.net/1822/73175.
  3. 3-bromopyruvate boosts the effect of chemotherapy in acute myeloid leukemia by reducing cell antioxidant defense. Single Cause Single Cure Foundation. Fundação para a Ciência e Tecnologia (FCT) through the PhD grant (SFR/BD/146065/2019). NewG Lab Pharma. 2020. Vieira, Joana Margarida Pereira; Celeiro, Sónia Pires; Granja, Sara Costa; Matos, Ana Catarina Barbosa; Preto, Ana; Queirós, Odília; Ko, Young; Casal, Margarida; Baltazar, Fátima. http://hdl.handle.net/1822/73254.
  4. 3-Bromopyruvate pre-treatment sensitizes MOLM13 and KG-1 cell lines to chemotherapy. Single Cause Single Cure Foundation. 2019. Vieira, Joana Margarida Pereira; Granja, Sara Costa; Matos, Ana Catarina Barbosa; Ko, Young; Preto, Ana; Queirós, Odília; Casal, Margarida; Baltazar, Fátima. http://hdl.handle.net/1822/73256.
  5. Exploring the Cyberlindnera jadinii transportome for the identification of novel carboxylate transporters. Considering the global problems of resource scarcity and environmental damage, new technologies based on renewable biological sources are needed as current model of natural resource exploitation is unsustainable. Novel strategies to boost bio-based production of organic acids are based on the expression of carboxylate transporters in microbial cell factories. In this work we have focused on the id. 2019. Sousa-Silva, M.; Vieira, Daniel; Ribas, David Manuel Nogueira; Soares, Pedro; Casal, Margarida; Soares-Silva, Isabel João. https://hdl.handle.net/1822/73030.
  6. Characterization of novel plasma membrane carboxylate transporters from non-conventional yeasts. Carboxylic acids (CAs) are a group of organic compounds that play a central role in cellular metabolism of many organisms, using it as unique sources of carbon and energy [1]. In order to replace conventional petroleum-based methods for the obtainment of CAs, alternatives are required for more sustainable way of producing these compounds. The exploitation of yeast biodiversity has received great i. 2019. Senra, Emanuel Sousa; Sousa-Silva, M.; Ribas, David Manuel Nogueira; Casal, Margarida; Soares-Silva, Isabel João. https://hdl.handle.net/1822/73048.
  7. Insights on signal-elicited endocytosis of yeast lactate transporters. Eukaryotic cells regulate their membrane protein repertoire by vesicle trafficking pathways such as endocytosis. Defects in this traffic event lead to protein accumulation and can result in several human diseases. In yeast, a-arrestins play a major role on the endocytosis of plasma membrane transporters, acting as signalling platforms and ubiquitin ligase adaptors. The Saccharomyces cerevisiae lac. 2018. Talaia, Gabriel; Gournas, Christos; Saliba, Elie; Antunes, Cláudia Barata; Casal, Margarida; André, Bruno; Diallinas, George; Paiva, Sandra. http://hdl.handle.net/1822/51233.
  8. Corrigendum to ‘‘Silk-based biomaterials functionalized with fibronectin type II promotes cell adhesion” [Acta Biomater. 47 (2017) 50–59]. The authors regret that Telma C. Bernardo was inadvertently omitted in the author line-up. The correct authorship order should be as follows: Ana Margarida Pereira, Raul Machado, André da Costa, Artur Ribeiro, Telma C. Bernardo, Tony Collins, Andreia C. Gomes, Isabel B. Leonor, David L. Kaplan, Rui L. Reis, Margarida Casal. Telma C. Bernardo participated in recombinant 6mer+FNII production and pur. 2017. Pereira, Ana Margarida Macedo Bernardes; Machado, Raul; da Costa, André; Ribeiro, Artur; Bernardo, Telma C.; Collins, Tony; Gomes, Andreia C; et al. http://hdl.handle.net/1822/73064.
    10.1016/j.actbio.2016.11.008
  9. A novel pathway for the endocytic regulation of Jen1 lactate transporter of Saccharomyces cerevisiae. NORTE-01-0145-FEDER-000009; PTDC/BIAMIC/5184/2014. info:eu-repo/semantics/publishedVersion. 2017. Talaia, Gabriel; Saliba, Elie; Gournas, Christos; Barata-Antunes, Cláudia; André, Bruno; Diallinas, George; Casal, Margarida; Paiva, Sandra. http://hdl.handle.net/1822/51305.
  10. Candida glabrata biofilm development on medical devices is modulated by the presence of alternative carbon sources.. Candida species are the most common cause of fungal infection in humans. Their capacity to cause disease is dependent on the ability to grow within the human host environment and to assimilate the carbon sources available. Previous studies have shown that the presence of alternative carbon sources influence the behaviour of these fungal pathogens, suggesting that some carboxylic acid transporters. 2017. Gonçalves, Alexandra; Alves, Rosana Maria Abreu; Casal, Margarida; Dijck, Patrick van; Paiva, Sandra. http://hdl.handle.net/1822/51004.
  11. 3-Bromopyruvate induces cytotoxicity, inhibits glycolysis and decreases migratory capacity in glioblastomas and colorectal cancer cell lines. CESPU project BioCat-CESPU-2016. 2016. Barbosa, Ana Margarida; Vieira, Joana Margarida Pereira; Miranda, Joana; Moreira, Roxana; Casal, Margarida; Queirós, Odília. http://hdl.handle.net/1822/73258.
  12. Towards an authentic architecture - Auguste Perret [comunicação oral]. 2016. Casal Ribeiro, Helder; Marques, Margarida. https://hdl.handle.net/10216/145905.
    10.13140/RG.2.2.20948.88962
  13. Carboxylic acid transportes Jen1 and Jen2 affect Candida albicans biofilms' formation and susceptibility to fluconazole. Candida spp. often inhabits niches that are glucose-limited but rich in alternative carbon sources (e.g. lactate, acetate), an ability that contributes to cells' virulence. In glucose-poor niches, Candida albicans cells express JEN1 and JEN2 genes encoding the carboxylic acids transporters Jen1 and Jen2, respectively, which have been reported to be important in the early stages of infection. In th. 2016. Alves, Rosana Maria Abreu; Mota, Sandra; Barata, Cláudia; Silva, Sónia Carina; Rodrigues, Célia Fortuna; Brown, Alistair; Henriques, Mariana; Casal, Margarida; Paiva, Sandra. http://hdl.handle.net/1822/51014.
  14. Analysis of the intracellular traffic and turnover of yeast membrane transporters using a novel domain swap strategy. info:eu-repo/semantics/publishedVersion. 2016. Talaia, Gabriel; Casal, Margarida; Diallinas, George; Paiva, Sandra. http://hdl.handle.net/1822/51301.
  15. Impact of alternative carbon sources and antifungal treatment on Candida glabrata biofilms' transcription profile. Candida glabrata is considered a major opportunistic fungal pathogen of humans and has emerged as a leading cause of nosocomial fungal infections. The capacity of this yeast species to cause infections is dependent on the ability to grow within the human host environment and to assimilate the carbon sources available. Previous studies have suggested that Candida can encounter glucose-poor microenv. 2016. Alves, Rosana Maria Abreu; Kastora, Stavroula; Pinho, Eva Patrícia Paiva Santos; Rodrigues, Célia Fortuna; Silva, Sónia Carina; Casal, Margarida; Alistair, Brown; Henriques, Mariana; Paiva, Sandra. http://hdl.handle.net/1822/51017.
    10.13140/RG.2.2.29676.77444
  16. The study of the endocytic trafficking of the yeast monocarboxylate transporter Jen1 from Saccharomyces cerevisiae. Poster apresentado no "XXXIX Portuguese Genetics Conference", em Braga, Portugal, 2015. The monocarboxylate transporter Jen1 of the yeast Saccharomyces cerevisiae has proven to be an excellent model system for genetically dissecting mechanisms that regulate trafficking of a eukaryotic plasma membrane protein, according to physiological constraints. Glucose triggers a rapid endocytosis of Jen1 bein. 2015. Talaia, Gabriel; Casal, Margarida; Diallinas, George; Paiva, Sandra. http://hdl.handle.net/1822/51220.
  17. Matéria-Prima, vol.3, nº2 (Jul./Dez. 2015). A educação pela arte faz-se através dos seus materiais, da sua operação, da transformação das matérias em ideias novas, em novas coisas. No seu sucesso está implicada uma literacia, uma capacidade interpretativa, ou crítica, sobre a semiosfera cada vez mais povoada, saturada de mensagens parasitárias. A educação implica uma leitura do mundo (Paulo Freire), que se projeta na interpretação de todas. 2015. Queiroz, João; Calado, Margarida; Oliveira, Elisabete Silva; Pessanha, Ana Maria Araújo; Leal, Alda Maria Encarnação Rodrigues; Liberato, Aline Fernanda Huber Vicente; Albuquerque, Isabel; et al. http://hdl.handle.net/10451/50906.
  18. Effective perinatal intensive care in europe (epice): Descrição do Projeto e primeiros resultados em Portugal. A melhoria da qualidade dos cuidados pré-natais e dos cuidados intensivos neonatais resultaram, nas últimas décadas, numa continuada diminuição da morbilidade e da mortalidade perinatais e infantis, particularmente de recém-nascidos muito pré-termo. No entanto, há uma grande variabilidade entre unidades de saúde na decisão sobre procedimentos e intervenções, quer a nível nacional quer internaciona. 2014. Barros,Henrique; Rodrigues,Carina; Costa,Raquel; Baía,Inês; Rodrigues,Teresa; Machado,Maria do Céu; Graça,Luís; et al. http://scielo.pt/scielo.php?script=sci_arttext&pid=S0871-34132014000600004.
  19. Key stress factors and parameters for batch production optimisation of silk-elastin-like proteins in E. coli. European Commission via the 7th Framework Programme Project EcoPlast. Fundação para a Ciência e a Tecnologia (FCT) via Ciência 2008.. 2011. Collins, Tony; Silva, J. Azevedo; Costa, A.; Machado, Raul; Casal, Margarida. http://hdl.handle.net/1822/15993.
  20. A colecção de Saccharomyces cerevisiae para a selecção de novas estirpes de vinificação. Na indústria vitivinícola, verifica-se actualmente uma procura acrescida de novas estirpes de leveduras, adaptadas a diferentes tipos e estilos de vinhos, no sentido da sua diversificação. Neste sentido, o Centro de Biologia Molecular e Ambiental (CBMA) da Universidade do Minho constituiu uma das maiores colecções de estirpes de Saccharomyces cerevisiae, obtidas a partir de ambientes vitivinícolas. 2010. Vieira, E.; Neves, J. Drumonde; Gambon, Brigitte; Valero, Eva; Gomes, Ana Catarina; Sousa, Susana; Lima, Maria Teresa; et al. http://hdl.handle.net/1822/12028.
  21. A Saccharomyces cerevisiae bio-databank for winemaking strain selection. The winemaking industry faces currently an increased demand for novel Saccharomyces cerevisiae strains that are well adapted to different wine styles and that contribute to improved aromatic characteristics. In this reasoning, the Centro de Biologia Molecular e Ambiental (CBMA) at the University of Minho gathered one of the largest bio-databanks of S. cerevisiae, obtained from winemaking environme. 2010. Vieira, E.; Neves, J. Drumonde; Gambon, Brigitte; Valero, Eva; Gomes, Ana Catarina; Sousa, Susana; Lima, Maria Teresa; et al. http://hdl.handle.net/1822/12018.
  22. Elastin-like protein production kinetics at different environmental conditions in Escherichia coli. Elastomeric proteins are known by their great resilient properties being able to withstand significant deformations without rupture, returning to their original state when the stress is removed. In this family we find elastin like polymers (ELPs) that have the ability to undergo inverse temperature transition1 along with other smart behaviour properties. Furthermore, they present astonishing bioco. 2007. Padrão, Jorge; Silva, Dina; Machado, Raul; Nobre, Alexandra; Casal, Margarida. http://hdl.handle.net/1822/53970.
  23. Biologia Molecular, bloco 1: expressão genética: guião das aulas práticas. http://hdl.handle.net/1822/18546. 2007. Casal, Margarida; Lucas, Cândida; Ferreira, Célia; Aguiar, Cristina; Paiva, Sandra; Pereira, Leonor; Vieira, N.; et al. http://hdl.handle.net/1822/18546.
  24. Response surface optimization of the culture medium for production of elastin-like polymers by E. coli. ASTM program POCI 2010 (project POCI/CTM/57177/2004) suported by FEDER and FCT. Elastin-Like Polymers (ELP`s), a family of proteins based on repetitive pentapeptide sequences known by their smart and extremely biocompatible behavior (1, 2), are of great interest to our research group. Ongoing work using E. coli as the expression system, strongly suggests that the biomass and polymer production are. 2007. Silva, D.; Padrão, Jorge; Machado, Raul; Teixeira, J. A.; Casal, Margarida; Nobre, Alexandra. http://hdl.handle.net/1822/54044.
  25. Identification of wine related yeast species by capillary electrophoresis single strand conformation polymorphism analysis (CE-SSCP) of the 26S rRNA Gene. Financially supported by the programs POCI 2010 (FEDER/FCT, POCTI/AGR/56102/2004, POCTI/AGR/56771/2004), and AGRO (ENOSAFE, Nº 762).. 2006. Dellinger, B.; Graça, Magda Maria Couto da Silva; Casal, Margarida; Schuller, Dorit Elisabeth. http://hdl.handle.net/1822/5972.
  26. Physical and chemical optimization of a synthetic medium for Pichia pastoris growth. The methylotrophic yeast Pichia pastoris is widely used as a host strain for the production of a variety of heterologous proteins. The basal salt medium (BSM) described by Invitrogen (2000) is one of the most broadly used media for this expression system, although it possesses many problems, namely unbalanced composition, salt precipitation and undesirable ionic strength. This medium also uses NH4. 2006. Padrão, Jorge; Machado, Raul; Nobre, Alexandra; Casal, Margarida. http://hdl.handle.net/1822/6119.
  27. A novel approach for the production of human recombinant BMP-2 for bone tissue engineering applications. Bone tissue engineering has been an increasing field of research during the last years. The ideal approach for a regenerative application would consist in the use of cells from the patient, scaffolding materials and differentiation growth factors. Bone morphogenetic protein-2 (BMP-2) is one such growth factors with a strong ability to induce new bone and cartilage formation and has been used as a. 2006. Bessa, Paulo C.; Pedro, A. J.; Nobre, Alexandra; Dungl, P.; Klosch, B.; Redl, Heinz; Casal, Margarida; Reis, R. L.. http://hdl.handle.net/1822/54026.
  28. Malic acid degradation by indigenous and commercial Saccharomyces cerevisiae wine strains. Malic acid contributes to the acidic taste of wine and is, together with tartaric acid, the most abundant organic acid in wine. Contaminating lactic acid bacteria cause wine spoilage after bottling and may use malic acid as a substrate. It is therefore essential to remove excess malic acid from wines to ensure their physical, biochemical and microbial stability. The aim of this work was to gain in. 2006. Pereira, Leonor; Schuller, Dorit Elisabeth; Queirós, Odília; Ferreira, Pedro Moradas; Casal, Margarida. http://hdl.handle.net/1822/6118.
  29. Expression, purification and in vitro biological activity from human recombinant BMP-2 produced by a novel approach. Bone morphogenetic proteins have promoted great biomedical interest due to their ability in inducing new bone formation when used as powerful osteoinductive components of several late-stage bone grafting products. Recombinant human bone morphogenetic protein-2 (rhBMP-2) is obtained from mammalian cell expressing systems in low amounts or from bacteria inclusion bodies after timeconsuming refolding. 2006. Bessa, Paulo C.; Pedro, A. P.; Nobre, Alexandra; Klosch, B.; Redl, Heinz; Reis, R. L.; Casal, Margarida. http://hdl.handle.net/1822/54019.
  30. Expression, purification and in vitro biological activity from human recombinant BMP-2 produced by a novel approach. Bone tissue engineering has been an increasing field of research during the last years. The ideal approach for a regenerative application would consist in the use of cells from the patient, scaffolding materials and differentiation growth factors. Bone morphogenetic protein-2 (BMP-2) is one such growth factors with a strong ability to induce new bone and cartilage formation and has been used as a. 2006. Bessa, Paulo C.; Pedro, A.; Nobre, Alexandra; Dungl, P.; Banerjee, A.; Dopler, D.; Klosch, B.; et al. http://hdl.handle.net/1822/54027.
  31. Assessment of environmental impact of commercial wine yeast in vineyard ecosystems. Modern winemaking practices and diversification of wine products involve an increasing quest for specialised wine yeasts. During the last two decades considerable efforts have been made to improve wine yeast strains through the use of new biotechnologies. In the present study we used commercial wine yeast currently used in wineries as a model to assess the potential environmental risks associated. 2005. Valero, Eva; Schuller, Dorit Elisabeth; Cambon, Brigitte; Casal, Margarida; Dequin, Sylvie. https://hdl.handle.net/1822/6078.
  32. Commercial yeast utilization and genetic structure of vineyard-associated Saccharomyces cerevisiae populations revealed by microsatellite analysis. Since the beginning of the 1980’s, the use of active dried Saccharomyces cerevisiae yeast starters has been extensively generalised. Today, the majority of wine production is based on the use of active dried yeast, which ensures rapid and reliable fermentations. The behaviour of these yeasts in the ecosystem of the vineyard is totally unknown as is their potential impact on the natural microflora.. 2005. Dellinger, B.; Machado, Sofia; Schuller, Dorit Elisabeth; Casal, Margarida. http://hdl.handle.net/1822/6109.
  33. Assessment of environmental impact of commercial wine yeast in vineyard ecosystems. Poster e resumo apresentados no congresso "Intrafood 2005 - Innovations in traditional foods", em Valencia, Espanha, em 2005.. Modern winemaking practices and diversification of wine products involve an increasing quest for specialised wine yeasts. During the last two decades considerable efforts have been made to improve wine yeast strains through the use of new biotechnologies. In the present st. 2005. Valero, Eva; Schuller, Dorit Elisabeth; Cambon, Brigitte; Casal, Margarida; Dequin, Sylvie. http://hdl.handle.net/1822/3622.
  34. The disruption of JEN1 from Candida albicans impairs the transport of lactate. Poster apresentado em XXI International Conference on Yeast Genetics and Molecular Biology, Gotemburgo, Suécia, 7 Jul. - 12 Jul. 2004. Portugal - grant POCTI/1999/BME/36625 (Eixo 2, Medida 2.3, QCAIII - FEDER). PRAXIS XXI/BD/18198/98. fellowship SFRH/BD/4699/2001. 2004. Paiva, Sandra; Silva, Isabel Soares; Kötter, Peter; Entian, Karl-Dieter; Casal, Margarida. http://hdl.handle.net/1822/2874.
  35. Is Saccharomyces cerevisiae azoreductase the plasma membrane ferric reductase?. Poster apresentado na International Conference on Plasma Membrane Redox Systems and their Role in Biological Stress and Disease, 7, Asilomar, Califórnia, Estados Unidos da América, 14-18 Abril 2004.. Unspecific bacterial reduction of azo dyes is a widely studied process in correlation with the biological treatment of coloured waste waters but the enzyme system associated to this bacterial capabili. 2004. Ramalho, Patrícia A.; Paiva, Sandra; Paulo, Artur Cavaco; Casal, Margarida; Ramalho, Maria Teresa; Cardoso, M. Helena. http://hdl.handle.net/1822/2253.
  36. Ady2p is essential for the acetate pemease activity in the yeast Saccharomyces cerevisae. Poster apresentado em 2004 Yeast Genetics and Molecular Biology Meeting, Seattle, USA, 27 Jul. - 1 Ag. 2004. Portuguese Government - Ph.D. Grant from the (BD/1898/98). FEBS - short term fellowship. Portuguese Government - Technichal Grant POCTI/BME/36625/2000 , POCTI/1999/36625. 2004. Paiva, Sandra; Devaux, Frederic; Barbosa, Sónia; Jacq, Claude; Casal, Margarida. http://hdl.handle.net/1822/2872.
  37. Métodos convencionais em microbiologia. 2004. Casal, Margarida; Schuller, Dorit Elisabeth; Rodrigues, Georgina Maria Martins; Pais, Célia. https://hdl.handle.net/1822/2241.
  38. A contribution for the identification of the azo reductase activity in intact yeast cells. Poster apresentado no International Congress on Yeasts (ICY) -Yeasts in Science and Biotechnology : The Quest for Sustainable Development", 11, Rio de Janeiro, Brasil, Agosto 2004.. Azo dyes are synthetic organic colorants which are extensively used in textile, food and cosmetic industries. A large fraction of these dyes is released into the environment even after conventional wastewater treatment. 2004. Ramalho, Patrícia A.; Paiva, Sandra; Paulo, Artur Cavaco; Casal, Margarida; Ramalho, Maria Teresa; Cardoso, M. Helena. http://hdl.handle.net/1822/2162.
  39. Reductive biological treatment of textile effluents. Poster apresentado no "Simpósio Corantes e Pigmentos Orgânicos", na Universidade de Trás-os-Montes e Alto Douro, em Vila Real, Portugal, em Novembro de 2004.. Our group is undertaking an investigation on the potential application of ascomycete yeasts to the decolourisation of azo dyes. Two of these strains, Candida zeylanoides (UM2) and Issatchenkia occidentalis (UM41), were isolated from contamin. 2004. Ramalho, Patrícia A.; Paiva, Sandra; Casal, Margarida; Ramalho, Maria Teresa; Cardoso, M. Helena; Paulo, Artur Cavaco. http://hdl.handle.net/1822/2247.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025 Invited Lecture- MICROBIAL CARBOXYLIC ACID MEMBRANE TRANSPORTERS : distinct features for importers and exporters. FCUL. Lisboa. 29 de maio de 2025.
Faculdade de Ciências de Lisboa (Lisboa, Portugal)
2024/11/18 Invited Lecture – CITRATE TRANSPORTERS IN FUNGI: distinct features for importers and exporters. Universidade de BOKU. Viena. Austria. 18 de novembro, 2024. Invited Lecture
BOKU. Viena. Austria. (Wien, Austria)
2024/04/21 O ensino e a investigação em BIOINFORMÁTICA na UMinho. 21 de abril de 2024. Universidade do Minho
(Portugal)
2022/03/11 Invited Lecture – Isabel Soares-Silva, Margarida Casal, 3D structure prediction and molecular docking for the study of carboxylate permeases - Membrane transporter engineering for the optimization of microbial cell factories. PSI-BIOTalia Theatre, Lisbon Portugal,11th March 2022
2021/03/10 Invited Lecture – Biosustainability in circular economy– bioengineering of microbial cell factories in the production of bioplastics. VII Jornadas de Bioengenharia. UTAD. Vila Real, Portugal,10th March 2021.
2020/06/22 Invited Lecture – Learning from nature: designing recombinant proteins for advanced biomaterials production. Advanced Course in "Biopolymers based on renewable resources: from synthesis to applications (5th Edition)". University of Minho, Braga, Portugal, 22nd June, 2020.
2019/07/04 Invited Lecture – The diversity of links between the functional and structural features of carboxylate transporters in prokaryotic and eukaryotic cells: implications in health and biotechnology. Universidade de BOKU. Viena. Austria. 4 de Julho de 2019
2018/09/29 Invited Lecture – Keynote 3. Learning from nature: biopolymer design with biomimetic properties and smart behavior. UCIBIO Annual Meeting. FCT NOVA, Campus Caparica. 29 September 2018.
2018/07/04 Invited Lecture - The diversity of links between the functional and structural features of carboxylate transporters in prokaryotic and eukaryotic cells: implications in health and biotechnology. 19th Biennial SFRRI meeting. Lisbon 4-7 July. 2018 19th Biennial SFRRI meeting
(Portugal)
2017/05/21 Invited Lecture - Breast cancer cell lines susceptibility to 3-bromopyruvate: understanding the role of monocarboxylate transporters. Post-graduated international course: Cancer therapy: from basic research to clinic. Departamento de Biologia, Campus de Gualtar. 21 de maio, 2017.
Universidade do Minho (Braga, Portugal)
2017/05/18 Invited Lecture - Learning from Nature: modular biomimetics for biopolymer design. HYBER Symposium 2017, Grand Marina, Centre of Excellence HYBER Aalto University, Helsinki, Finland. 18 de Maio. HYBER Symposium 2017
HYBER Symposium 2017, Grand Marina, Centre of Excellence HYBER Aalto University, Helsinki, Finland. 18 de Maio. (Helsinki, Finland)
2017/02/23 Invited Lecture - On the diversity of links between transport and metabolism of carboxylic acids. António V. Xavier Seminars, ITQB, Oeiras, 23 Fevereiro, 2017. António V. Xavier Seminars, ITQB, Oeiras, 23 Fevereiro, 2017.
UniVersidade Nova (Oeiras, Portugal)
2016/06/03 Invited Lecture - Engineering Synthetic Biopolymers -with biomimetic properties and smart behavior. Jornadas Portuguesas de Genética. Universidade de Coimbra. 3 de Junho 2016.
SPG (Coimbra, Portugal)
2016/05/05 Invited Lecture - Transport of lactic acid across plasma membrane: the common features between yeast and cancer cells. Post-graduate international course Protein degradation and trafficking in health and disease. Departamento de Biologia, Campus de Gualtar. 5 de maio, 2016.
UMinho (Braga, Portugal)
2016/02/19 Invited Lecture - A relevância social do conhecimento sobre o genoma humano. Encontro CERACeG - Encontro sobre Contextualização do Ensino e Relevância da Aprendizagem das Ciências e da Geografia. Instituto de Educação da Universidade do Minho. 19 de fevereiro de 2016.
Universidade do Minho (Braga, Portugal)
2015/12/02 Invited Lecture - Synthetic Biology as a Powerful Tool in The Development of Advanced Materials. Seminários enquadrado no âmbito do Mestrado em Biofísica e Bionanossistemas. Escola de Ciências UMinho.
UMinho (Braga, Portugal)
2014/07/01 Invited Lecture - Transport of lactic acid across plasma membrane: implications in health and biotechnology. University of Milano-Bicocca, Italy. YeastCell Symposium
University of Milano-Bicocca, Italy. 1 de Julho 2014. (Milano, Italy)
2013/09/28 Keynote speaker Lecture N. Van Uden: When physiology meets structural biology: the story of lactate transporters in yeast. Small Meeting in Yeast Transport and Energetics (SMYTE 31). September 24-28 2013. Antalya, Turkey
Scientific committee (Antalya, Turkey)
2013/06/09 Keynote Lecture Synthetic Biology as a powerful tool in the development of bioinspired smart materials. First Interantional Conference on Natural Fibers: Sustainable Materials and Advanced Applications. Guimarães, Portugal. 9-11 june, 2013.
(Guimarães, Portugal)
2013/05/10 INVITED LECTURE: Breast cancer cell lines susceptibility to 3-bromopyruvate: understanding the role of monocarboxylate transporters. Universidade de Atenas, Grécia, 10 May, 2013. Lectures.
Universidade de Atenas, Grécia, 10 May, 2013. (Atenas, Greece)
2013/05/09 INVITED LECTURE - Synthetic Biology as a source of inspiration to design advanced biopolymers. Universidade de Atenas, Grécia, 9 May , 2013 Lectures.
Universidade de Atenas, Grécia, 9 May , 2013 (Atenas, Greece)
2012/10/16 INVITED LECTURE: Synthetic Biology as a source of inspiration to design advanced biopolymers. 16 October 2012. Invited speaker on the Celebrating Industrial Biotechnology Day, a VTT tribute to Merja Penttilä who has received the Wihuri Foundation International Prize for her prominent work in industrial biotechnology.
VTT (Espoo, Finland)
2012/06/03 INVITED LECTURE: The role and regulation of monocarboxylate transporters families in bacteria, yeast and cancer cells. Faculty of Bioscience Engineering, Leuven, Belgium. Lectures.
Faculty of Bioscience Engineering, Leuven, Belgium. (Leuven, Belgium)
2012/05/25 INVITED LECTURE - Transport of lactic acid across plasma membrane: implications in health and biotechnology. 25 May 2012, University of Gothenburg, Sweden. University of Gothenburg, Sweden.
University of Gothenburg, Sweden. (Gothenburg, Sweden)

Supervision

Thesis Title
Role		 Degree Subject (Type)
Institution / Organization
2024/10/01 - 2026/02/10 Modelling carboxylic acid transporter proteins for the improvement of microbial cell factories
Co-supervisor
 Mestrado em Genética Molecular
Universidade do Minho, Portugal
2023/06/01 - 2025/06/01 Characterization of carboxylate transporters in yeasts
Co-supervisor
 Mestrado em Genética Molecular (Master)
Universidade do Minho, Portugal
2023/10/01 - 2025/02/20 Produção de um Bioadesivo Recombinante Bioinspirado
Co-supervisor
 Mestrado em Genética Molecular (Master)
Universidade do Minho, Portugal
2020/02/01 - 2024/11/21 Yeast as a model system for the study of carboxylic acid transporters
Supervisor
 Programa Doutoral em Biologia Molecular e Ambiental (PhD)
Universidade do Minho, Portugal
2019/10/01 - 2023 Role of monocarboxylate transporters in the resistance phenotype of acute leukemia: therapeutic implications
Supervisor of Joana Margarida Pereira Vieira
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2019 - 2022 Engineering Plasma Membrane Transporters to Improve Organic Acid Production
Supervisor of Toni Rendulic
 Biologia (PhD)
Universidade do Minho, Portugal
2017 - 2021 Identification and functional characterization of novel plasma membrane carboxilate transporters
Supervisor of Maria Antónia Sousa Correia da Silva
 Biologia Molecular e Ambiental (PhD)
Universidade do Minho, Portugal
2017 - 2020 Function and regulation of Candida glabrata and C. albicans carboxylic acid transporters and their role in biofilm formation, antifungal drug resistance and phagocytosis
Supervisor of Rosana Maria Abreu Alves
 Biologia Molecular e Ambiental (PhD)
Universidade do Minho, Portugal
2016 - 2020 Insights into the mechanism of antimicrobial activity and its exploitation for developing new therapies against clinically relevant bacteria
Supervisor of Ana Margarida Macedo Bernardes Pereira
 Biologia Molecular e Ambiental (PhD)
Universidade do Minho, Portugal
2012 - 2019 Endocytic trafficking and ubiquitylation of plasma membrane transporters in yeast.
Co-supervisor of Gabriel Azevedo Carreira Talaia da Rocha
 Biologia Molecular e Ambiental (PhD)
Universidade do Minho, Portugal
2009 - 2019 Novos produtos biotecnológicos e serviços para a indústria dos vinhos
Supervisor of Maria Eugénia Gonçalves Vieira
 Biologia (PhD)
Universidade do Minho, Portugal
2015 - 2018 Characterization of carboxylate transporters: functional and structural studies for the improvement of cell factories
Supervisor of David Manuel Nogueira Ribas
 Biologia Molecular e Ambiental (PhD)
Universidade do Minho, Portugal
2016 - 2017 Functional expression of transporters in yeast
Supervisor of Ana Carolina Gomes Almeida
 Bioquímica Aplicada (Master)
Universidade do Minho, Portugal
2016 - 2017 Formulation of biocomposites based on recombinant proteins and plant essential oils for the development of active wound dressings
Co-supervisor of Diana Cristina Serra Gomes
 Biologia Molecular, Biotecnologia e Bioempreendedorismo em Plantas (Master)
Universidade do Minho, Portugal
2016 - 2017 Molecular Mechanisms Involved in 3-Bromopyruvate Effect in Colorectal Cancer Cell Lines
Co-supervisor of Joana Margarida Pereira Vieira
 Genética Molecular (Master)
Universidade do Minho, Portugal
2013 - 2017 Functionalization of protein-based polymers for advanced biomaterials
Supervisor of André Manuel Abreu da Costa
 Biologia Molecular e Ambiental (PhD)
Universidade do Minho, Portugal
2013 - 2017 The role of monocarboxylate transporters in 3-bromopyruvate effect in cancer cells
Supervisor of João Pedro Azevedo Silva
 Biologia Molecular e Ambiental (PhD)
Universidade do Minho, Portugal
2016 - 2016 Creation of databases of ageing-related drugs and statistical analysis and applied machine learning for the prioritization of potential lifespan-extension drugs
Co-supervisor of Diogo Gonçalves Barardo
 Biofísica e Bionanossistemas (Master)
Universidade do Minho, Portugal
2016 - 2016 Structural studies of succinate acetate transporter and type II NADH dehydrogenase
Co-supervisor of Diogo Pinto Pereira de Athayde
 Bioquímica Aplicada (Master)
Universidade do Minho, Portugal
2016 - 2016 Unravelling the molecular mechanismsunderlying 3-bromopyruvate resistance in tumor cell lines
Co-supervisor of Ana Margarida Oliveira Barbosa
 Terapias Moleculares (Master)
Instituto Universitário de Ciências da Saúde, Portugal
2015 - 2015 Production of silk-elastin-like composite materials with antimicrobial properties
Co-supervisor of Andreia Maria Azevedo da Silva
 Bioquímica Aplicada (Master)
Universidade do Minho, Portugal
2015 - 2015 Fed-batch production of a silk-elastin-like protein: investigating plasmid stabilisation and glycerol as carbon source
Co-supervisor of Paulo Jorge Barbosa Rodrigues
 Bioquímica Aplicada (Master)
Universidade do Minho, Portugal
2011 - 2015 Design, bioproduction and characterization of protein recombinant silk-elastin-based polymers - a new class of nano-biomaterials
Supervisor of Raul Miguel Ribeiro Machado
 Ciências (PhD)
Universidade do Minho, Portugal
2014 - 2014 A molecular biotechnological approach for the development of Silk-elastin-like proteins functionalized with leukemia inhibitory factor
Co-supervisor of Rute Malarranha Chitas
 Genética Molecular (Master)
Universidade do Minho, Portugal
2013 - 2014 3-Bromopyruvate as an anticancer agent in breast cancer cell lines: exploring the role of monocarboxylate transporters
Supervisor of Ana Luísa Ferreira Ribeiro
 Genética Molecular (Master)
Universidade do Minho, Portugal
2000 - 2014 Study of the mechanisms of transport and regulation of carboxylic acids in Candida albicans and Candida glabrata
Co-supervisor of Sandra Mota
 Biologia Molecular e Ambiental (PhD)
Universidade do Minho, Portugal
2013 - 2013 Optimisation of the fed-batch production of a silk-elastin-like protein: overcoming acetate accumulation and plasmid instability
Co-supervisor of Mário Jorge Faria Barroca
 Biofísica e Bionanossistemas (Master)
Universidade do Minho, Portugal
2013 - 2013 Structural-functional studies of carboxylic acid transporters: novel tools in production optimization using industrial microbes
Supervisor of David Manuel Nogueira Ribas
 Genética Molecular (Master)
Universidade do Minho, Portugal
2012 - 2013 Thiol-disulphide oxidoreductases : production, purification and structural analysis of a cold adapted DsbA
Co-supervisor of Catherine Oliveira Ferreira
 Genética Molecular (Master)
Universidade do Minho, Portugal
2009 - 2013 Structural-functional studies of plasma membrane carboxilate transporters in yeast
Supervisor of Joana Margarida Sá Pessoa da Graça Santos
 Biologia Molecular e Ambiental (PhD)
Universidade do Minho, Portugal
2009 - 2010 Cloning and expression of antimicrobial peptides and their evaluation for biotechnological applications
Supervisor of André da Costa
 Genética Molecular (Master)
Universidade do Minho, Portugal
2006 - 2010 The transport of carboxylic acids in yeasts : from physiology towards structural-functional characterization of permeases
Co-supervisor of Neide Marina Vieira Pereira
 Biologia (PhD)
Universidade do Minho, Portugal
2005 - 2009 Novel biodegradable drug delivery systems for the controlled release of growth factors in bone healing and tissue engineering
Supervisor of Paulo Bessa
 Biologia (PhD)
Universidade do Minho, Portugal
2005 - 2009 Recombinant carbohydrate-binding modules for biomedical applications Biocompatibility of polysaccharide-based materials
Co-supervisor of Susana Margarida Gomes Moreira
 Engenharia Química e Biológica (PhD)
Universidade do Minho, Portugal
2008 - 2008 Molecular Biotechnology Approaches Towards Optimization of Enzymes for Advanced Textile Applications
Co-supervisor of Rita Isabel Lima de Araújo
 Ciências (PhD)
Universidade do Minho, Portugal
2002 - 2006 Characterization of Monocarboxylate Permeases in Yeast - Functional and Structural Analysis
Supervisor of Isabel João Soares da Silva
 Ciências (PhD)
Universidade do Minho, Portugal
2002 - 2006 Molecular Biology of Monocarboxylic Acids Permeases in Yeast
Supervisor of Neide Marina Vieira Pereira
 Ciências (PhD)
Universidade do Minho, Portugal
2004 - 2005 Polimorfismo no gene da Ciclina D1 em neoplasias associadas a vírus
Co-supervisor of Raquel Jorge Ferreira Catarino
 Genética Molecular (Master)
Universidade do Minho, Portugal
2000 - 2004 Genetic diversity and molecular characterization of Saccharomyces cerevisiae strains from winemaking environments
Supervisor of Dorit Elisabeth Schuller
 Biologia (PhD)
Universidade do Minho, Portugal
1999 - 2002 Transporte e Utilização de Ácidos Dicarboxílicos nas Leveduras Kluyveromyces Sp. e Saccharomyces cerevisiae: uma Abordagem Fisiológica, Bioquímica e Genética
Supervisor of Odília dos Anjos Pimenta Marques de Queirós
 Ciências (PhD)
Universidade do Minho, Portugal
1999 - 2002 Molecular Characterization of the Jen1 Coding for a Monocarboxylate. Transportes in Saccharomyces cerevisiae - Gene Expression Studies
Supervisor of Raquel Gláucia Varzielas Pego de Andrade
 Ciências (PhD)
Universidade do Minho, Portugal
1999 - 2002 Identification and Characterization of Plasma Membrane Monocarboxy Lactate Transporters in Saccharomyces cerevisiae and Candida albicans
Supervisor of Sandra Cristina Almeida Paiva
 Ciências (PhD)
Universidade do Minho, Portugal

Event organisation

Event name
Type of event (Role)		 Institution / Organization
2021/11/23 - 2021/11/26 Scientific committee and Chair person. MICROBIOTEC 21. MICROBIOTEC’21 (online version). NOVA University of Lisbon, Portugal, Nov 23-26, 2021. (2021/11/23 - 2021/11/26)
Congress (Member of the Scientific Committee)
 Sociedade Portuguesa de Microbiologia, Portugal
2020 - 2020 Scientific committee - Congresso Nacional de Bioquímica. Dezembro 2020. Universidade de Évora. Évora. (2020 - 2020)
Congress (Member of the Scientific Committee)
 Sociedade Portuguesa de Bioquímica, Portugal
2019 - 2019 Scientific committee - Congresso Nacional MICROBIOTEC’19. 5-7 dezembro 2019. Universidade de Coimbra. Coimbra. (2019 - 2019)
Congress (Member of the Scientific Committee)
 Sociedade Portuguesa de Microbiologia, Portugal
2019 - 2019 Chair person. 6th International Society of Cancer Metabolism (IsCam) annual meeting, Cancer metabolic rewiring: mapping the road to clinical translation. Braga, 17-19 Outubro, 2019. (2019 - 2019)
Congress (Other)
2018 - 2018 Scientific committee - XLII Jornadas Portuguesas de Genética. 2018. Junho 14-15 Porto. (2018 - 2018)
Congress (Member of the Scientific Committee)
 Sociedade Portuguesa de Genética, Portugal
2017 - 2017 Scientific committee - Congresso Nacional MICROBIOTEC’17. 10-12 dezembro 2017. Universidade Católica Portuguesa. Porto. Coordenadora de Painel. (2017 - 2017)
Congress (Member of the Scientific Committee)
 Sociedade Portuguesa de Microbiologia, Portugal
2017 - 2017 Scientific committee - XLI Jornadas Portuguesas de Genética. 2017. Junho 7-8. Aveiro. (2017 - 2017)
Congress (Member of the Scientific Committee)
 Sociedade Portuguesa de Genética, Portugal
2016 - 2016 President - XIX Congresso Nacional de Bioquimica. 8 – 10 Dezembro, Campus de Azurém, Universidade do Minho, Guimarães, 2016. (2016 - 2016)
Congress (President of the Organising Committee)
 Sociedade Portuguesa de Bioquímica, Portugal
2016 - 2016 Scientific committee - XL Jornadas Portuguesas de Genética. 2016. Junho 2-3. Coimbra. (2016 - 2016)
Congress (Member of the Scientific Committee)
 Sociedade Portuguesa de Genética, Portugal
2016 - 2016 Chair person – PYFF 2016 PYFF6 - Sixth Conference on Physiology of Yeasts and Filamentous Fungi - Session in Transport, Signalling and Intracellular Trafficking. 11-14 July 2016, Lisbon. (2016 - 2016)
Congress (Other)
2016 - 2016 Chair person – SMYTE 34 – Small Meeting in Yeast Transport and Energetics, 29 August-1 September, 2016, Crete, Greece. (2016 - 2016)
Congress (Other)
2015 - 2015 President - XXXIX Jornadas Portuguesas de Genética. 25 - 27 Maio, Campus de Gualtar, Universidade do Minho, Braga, 2015. (2015 - 2015)
Congress (President of the Organising Committee)
 Sociedade Portuguesa de Genética, Portugal
2015 - 2015 Scientific committee - Congresso Nacional MICROBIOTEC’15. 10-12 dezembro 2015. Universidade de Évora, Évora. Coordenadora de Painel. (2015 - 2015)
Congress (Member of the Scientific Committee)
 Sociedade Portuguesa de Microbiologia, Portugal
2015 - 2015 President - International Congress SMYTE33. Universidade de Lisboa, ISA_UL). 21 a 24 Julho 2015. (2015 - 2015)
Congress (Co-organisor)
2013 - 2013 Scientific committee - XXXVIII Jornadas Portuguesas de Genética . 4-5 junho, IBMC, ICBAS, Universidade do Porto, Porto, 2013. (2013 - 2013)
Congress (Member of the Scientific Committee)
 Sociedade Portuguesa de Genética, Portugal
2013 - 2013 Scientific committee- Congresso Nacional MICROBIOTEC’13. dezembro 2013. Universidade de Aveiro, Aveiro. (2013 - 2013)
Congress (Member of the Scientific Committee)
 Sociedade Portuguesa de Microbiologia, Portugal
2012 - 2012 Scientific committee- XXXVII Jornadas Portuguesas de Genética. 28-30 Maio, Universidade de Nova de Lisboa, Lisboa, 2012. (2012 - 2012)
Congress (Member of the Scientific Committee)
 Sociedade Portuguesa de Genética, Portugal
2011 - 2011 Scientific committee - XXXVI Jornadas Portuguesas de Genética. 31 Maio – 1 Junho, Universidade de Coimbra, Coimbra, 2011. (2011 - 2011)
Congress (Member of the Scientific Committee)
 Sociedade Portuguesa de Genética, Portugal
2011 - 2011 Scientific committee - Congresso Nacional MICROBIOTEC’11. 1-3 dezembro 2011. Universidade do Minho, Campus de Gualtar, Braga. (2011 - 2011)
Congress (Member of the Scientific Committee)
 Sociedade Portuguesa de Microbiologia, Portugal
2011 - 2011 Scientific committee - 34º World Congress of Wine and Wine /Congresso Mundial da Vinha e do Vinho. Porto, Portugal. 20-27 de Junho de 2011. (2011 - 2011)
Congress (Member of the Scientific Committee)
2011 - 2011 President - Workshop Internacional “Biopolymers based on renewable resources: from synthesis to applications”, uma iniciativa do projecto europeu FP7 EcoPlast. Braga, Universidade do Minho, Portugal. 8 de Junho de 2011. (2011 - 2011)
Workshop (President of the Organising Committee)
2010 - 2010 President - XXXV Jornadas Portuguesas de Genética. 31 Maio – 2 Junho, Campus de Gualtar, Universidade do Minho, Braga, 2010 (2010/05/30 - 2010/06/02)
Congress (President of the Organising Committee)
 Sociedade Portuguesa de Genética, Portugal
2010 - 2010 Scientific committee - Congresso Nacional de Bioquimica, simpósio Biotecnologia. Porto, 15-18 de Dezembro de 2010. (2010 - 2010)
Congress (Member of the Scientific Committee)
 Sociedade Portuguesa de Bioquímica, Portugal
2009 - 2009 Scientific committee - Congresso Nacional Micro09/ Biotec09/ XXXIV JPG, 28-30 de Novembro, 2009, Vila Moura. (2009/11/28 - 2009/11/30)
Congress (Member of the Scientific Committee)
 Sociedade Portuguesa de Microbiologia, Portugal

Sociedade Portuguesa de Genética, Portugal
2009 - 2009 Scientific committee - 5th European Symposium on Biopolymers ESBP2009, Funchal, Madeira, Portugal. 18-20 Novembro de 2009. (2009 - 2009)
Symposium (Member of the Scientific Committee)
2008 - 2008 President International Congress Internacional SMYTE26. Braga, Universidade do Minho, Portugal. 6 a 9 Setembro 2008. (2008 - 2008)
Congress (Co-organisor)
2007 - 2007 Scientific Committee - Congresso Nacional Micro 07/ Biotec 07/ XXXIII JPG, 31 de Novembro a 3 de Dezembro, 2007, Lisboa. (2007/11/30 - 2007/12/03)
Congress (Member of the Scientific Committee)
 Sociedade Portuguesa de Genética, Portugal
2006 - 2006 Organizing Committee - XXXII Jornadas Portuguesas de Genética. UTAD, Vila Real, 2 a 5 de Maio, 2006. (2006/04/02 - 2006/05/05)
Congress (Member of the Organising Committee)
 Sociedade Portuguesa de Genética, Portugal
2005 - 2005 Coordenation of a symposium - 13as Jornadas de Biologia de Leveduras Professor N. van Uden. Vila Real, 2005. (2005 - 2005)
Congress (Other)
2005 - 2005 President - 1º Congresso Nacional MicroBiotec´2005. Póvoa de Varzim, 30 de Novembro a 3 de Dezembro, 2005 (2005/11/30 - 2005/12/03)
Congress (President of the Organising Committee)
2005 - 2005 President - Workshop “Natural Polymers: the challenges for engineering applications”. Projecto NaturPlas. Braga, Universidade do Minho, Portugal. 8 de Junho de 2005. (2005 - 2005)
Workshop (President of the Organising Committee)
2004 - 2004 Coordenation of a symposium - 12as Jornadas de Biologia de Leveduras Professor N. van Uden. Aveiro, 2004. (2004)
2003 - 2003 Organizing Committee - Comissão Organizadora - Encontro de Docentes de Genética do Ensino Superior, uma iniciativa da Sociedade Portuguesa de Genética. Ponte de Lima, 21 e 22 de Julho de 2003. (2003/07/21 - 2003/07/22)
Meeting (Member of the Organising Committee)
2003 - 2003 Scientific Committee - Congresso Nacional de Microbiologia, MICRO´2003. (Sociedade Portuguesa de Microbiologia), integrada na equipa coordenadora do Simpósio Microbiologia Molecular e Celular. Tomar, 29 de Novembro a 2 de Dezembro de 2003. (2003/11/29 - 2003/12/02)
Congress (Member of the Scientific Committee)
2002 - 2002 Coordenation of a symposium - 10as Jornadas de Biologia de Leveduras Professor N. van Uden. Faro, 2002. (2002 - 2002)
1998 - 1998 Organizing committee - 19th ISSY - Yeast in the production and spoilage of food and beverages, Braga, Portugal. 30 de Agosto a 3 de Setembro de 1998. (1998 - 1998)
Congress (Member of the Organising Committee)
1996 - 1996 Organizing Committee - X Congresso Nacional de Bioquímica, Braga, 31 de Outubro a 2 de Novembro de 1996. (1996/10/31 - 1996/11/02)
Congress (Member of the Organising Committee)
 Sociedade Portuguesa de Bioquímica, Portugal
1994 - 1994 Organizing Committee - 2as Jornadas de Biologia de Leveduras Professor Nicolau van Uden, Braga, 20 e 21 de Maio de 1994. (1994/05/20 - 1994/05/21)
Congress (Member of the Organising Committee)
 Sociedade Portuguesa de Microbiologia, Portugal

Jury of academic degree

Topic
Role		 Candidate name (Type of degree)
Institution / Organization
2026/03/12 Arguente nas provas de agregação da Doutora Andreia Cristina Silva Viegas Mata Figueiredo, em Biologia, na especialidade de Biologia Celular e Molecular. 12 de Março de 2026, Faculdade de Ciências da Universidade de Lisboa
(Thesis) Main arguer
 Andreia Cristina Silva Viegas Mata Figueiredo (Aggregation)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
2026/02/26 Presidente nas provas de Carla Erica Olund Matos. Programa Doutoral em Biologia Molecular e Ambiental com a tese intitulada “Bioinformatic approaches to the genomic and epidemiological study of hospital- and community-acquired Klebsiella pneumoniae infections ". 26 de fevereiro 2026.
President of the jury
 Carla Erica Olund Matos (PhD)
2026/02/25 Presidente nas provas de Ticiana Barbosa Fernandes. Programa Doutoral em Biologia Molecular e Ambiental com a tese intitulada “Biotechnological potential of non-Saccharomyces yeasts for the production of added-value compounds using biowaste-derived substrates". 25 de fevereiro 2026.
President of the jury
 Ticiana Barbosa Fernandes (PhD)
Universidade do Minho, Portugal
2026/02/06 Arguente nas provas de agregação da Doutora Ana Margarida da Costa Macedo Fortes, em Biologia, na especialidade de Biologia Celular e Molecular. 6 de Fevereiro de 2026, Faculdade de Ciências da Universidade de Lisboa
(Thesis) Arguer
 Ana Margarida da Costa Macedo Fortes (Aggregation)
2026 Presidente nas provas de Mariana Rita Amorim Rodrigues. Doutoramento no âmbito do Programa Doutoral em Biologia Molecular e Ambiental, com a tese intitulada "Antagonism of Wickerhamomyces anomalus Against Phytopathogens and the Impact of Climate Variability on Olive and Chestnut Crops ". 19 de janeiro de 2026.
President of the jury
 Mariana Rita Amorim Rodrigues (PhD)
Universidade do Minho, Portugal
2026 Presidente nas provas de Rita Maria Martins Alves. Programa Doutoral em Biologia Molecular e Ambiental com a tese intitulada “Contact Lens Materials: An ecosystem issue and a contribution to a circular economy ". 16 de março 2026
President of the jury
 Rita Maria Martins Alves (PhD)
Universidade do Minho, Portugal
2025 Presidente nas provas de Leslie Ann Silva Amaral. Doutoramento do Programa Doutoral em Biologia Molecular e Ambiental com a tese intitulada " A humanized yeast model system to assess the risk of environmental pollutants to Parkinson's disease progression”. 8 de Julho de 2025.
President of the jury
 Leslie Ann Silva Amaral (PhD)
Universidade do Minho, Portugal
2025 Presidente nas provas de Flávia Natacha Silva Sousa. Doutoramento do Programa Doutoral em Biologia Molecular e Ambiental com a tese intitulada "Elucidation of the molecular basis underlying complex traits of Torulaspora delbrueckii: toward its industrial exploitation”. 26 de Junho de 2025.
President of the jury
 Flávia Natacha Silva Sousa (PhD)
Universidade do Minho, Portugal
2025 Presidente nas provas de João Tadeu Fontes. Doutoramento do Programa Doutoral em Biologia Molecular e Ambiental com a tese intitulada " Bioinformatics in Support of DNA-based Fish Monitoring and Screening of Intraspecific Genetic Divergence in Eastern Atlantic Ichthyofauna”. 18 de Junho de 2025.
President of the jury
 João Tadeu Fontes (PhD)
Universidade do Minho, Portugal
2025 Presidente nas provas de André Luís Oliveira Ferreira. Doutoramento do Programa Doutoral em Biologia Molecular e Ambiental com a tese intitulada "DNA-based monitoring of ichthyoplankton for application to fish biodiversity conservation and fisheries management”. 19 de Maio de 2025.
President of the jury
 André Luís Oliveira Ferreira (PhD)
Universidade do Minho, Portugal
2025 Presidente nas provas de Henrique Emanuel Araújo Silva. Doutoramento do Programa Doutoral em Biologia Molecular e Ambiental com a tese intitulada "G4CANCER – Green graphene/lipid nanosystems for cancer imaging and treatment". 4 de Abril de 2025.
President of the jury
 Henrique Emanuel Araújo Silva (PhD)
Universidade do Minho, Portugal
2025 Presidente nas provas de Maria Inês da Costa Pacheco. Doutoramento do Programa Doutoral em Biologia Molecular e Ambiental com a tese intitulada " Combined action of benzo[a]phenoxazine derivatives and fluconazole against Candida spp.". 13 de março de 2025.
President of the jury
 Maria Inês da Costa Pacheco (PhD)
Universidade do Minho, Portugal
2025 Presidente nas provas de Ana Sofia de Castro Lavrador. Doutoramento do Programa Doutoral em Biologia Molecular e Ambiental com a tese intitulada "Optimization of DNA-metabarcoding for the early detection and improved monitoring of non-indigenous species (NIS) in Portuguese coastal ecosystems". 5 de março de 2025.
President of the jury
 Ana Sofia de Castro Lavrador (PhD)
Universidade do Minho, Portugal
2025 Presidente nas provas de Vanessa Tatiana Pinho. Doutoramento do Programa Doutoral em Biologia Molecular e Ambiental com a tese intitulada "(Nano)structured bioactive materials for the delivery of pleiotropic leukemia inhibitory factor”. 28 de fevereiro de 2025.
President of the jury
 Vanessa Tatiana Pinho (PhD)
Universidade do Minho, Portugal
2025 Presidente nas provas de Ana Rita Pinto Brás. Doutoramento do Programa Doutoral em Biologia Molecular e Ambiental com a tese intitulada "New ruthenium-based anticancer agents: promising therapeutic approach towards colorectal cancer”. 10 de janeiro de 2025.
President of the jury
 Ana Rita Pinto Brás (PhD)
Universidade do Minho, Portugal
2024/11/18 Arguente principal nas provas de Yuelag Yao, Biomolecular Technology of Protein doctoral program com a tese intitulafa “Screening of the Acetate Transport Protein”. Institute of Bioprocess Science and Engineering, Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna. 18 de Novembro de 2024
(Thesis) Main arguer
 Yuelag Yao (PhD)
2024/11/01 Membro da Comissão externa de avaliação. Examinador externo. SONIA ALBILLOS ARENAL com a tese intitulada " Metabolic adaptations of Saccharomyces yeasts to wine Fermentation: Exploring their molecular bases". Doctorado en Biomedicina y Biotecnología. University de Valência, Espanha, sob a supervisão de AMPARO QUEROL e ELADIO BARRIO. November 2024.
(Thesis) Arguer
 SONIA ALBILLOS ARENAL (PhD)
2024/03/04 Arguente nas provas de Pablo Carril Vaglini, em Biologia, com a tese "A multidisciplinary study to investigate Herbaspirillum seropedicae-mediated priming in the wheat holobiont” Universidade de Lisboa, 4 de março 2024.
(Thesis) Main arguer
 ablo Carril Vaglini, em Biologia (PhD)
2024/02/26 Arguente principal nas provas de Paulo César Fernandes da Silva em Biologia, s com a tese "Metabolic engineering of sustainable branched chain unsaturated fatty acid production in Saccharomyces cerevisiae ". Universidade do Minho. 26 de fevereiro 2024
(Thesis) Main arguer
 Paulo César Fernandes da Silva (PhD)
2024/01/12 Arguente nas provas de agregação da Doutora Lucília Helena Ataíde Saraiva, em Ciências Farmacêuticas, no ramo de conhecimento de Biotecnologia Molecular e Celular Aplicada às Ciências da Saúde. 11 e 12 de Janeiro de 2024, Faculdade de Farmácia da Universidade do Porto.
(Thesis) Main arguer
 Lucília Helena Ataíde Saraiva (Aggregation)
2023/05/26 Arguente e membro do comité de avaliação nas provas do Maurizio Mormino em Biociencias- Biotecnologia Industrial, sob orientação de Yvonne Nygard e Verena Siewers, com a tese Exploring Saccharomyces cerevisiae’s responses to acetic acid and other inhibitors found in lignocellulosic hydrolysates. Chalmers University, Suécia, 26 de maio de 2023.
(Thesis) Arguer
 Maurizio Mormino (PhD)
Chalmers tekniska högskola - Campus Lindholmen, Sweden
2022/10/12 Arguente principal nas provas do Ricardo Aguilar Andrade Ribeiro em Biociencias e Biotecnologia sob orientação de Isabel Sá-Correia, com a tese Yeast adaptive response and tolerance to acetic acid stress: focus on the cell envelope. IST, Lisboa, 12 de outubro de 2022.
(Thesis) Main arguer
 Ricardo Aguilar Andrade Ribeiro (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2022/09/26 Arguente nas provas de Lorena Donzella. Doutoramento em Biologia da UMinho, sob orientação de Maria João Marques Ferreira de Sousa Moreira e Doutor John P. Morrissey, com a tese "Characterization and engineering of sugar transporters in the yeast Kluyveromyces marxianus for biotechnological applications". UMinho, 26 de setembro, 2022.
(Thesis) Arguer
 Lorena Donzella (PhD)
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2022/04/06 Arguente nas provas de agregação da Doutora Manuela Alexandra de Abreu Serra Marques Pereira, em Bioquímica, 5 e 6 de Abril de 2022, Faculdade de Ciências da Universidade de Lisboa.
(Thesis) Arguer
 Manuela Alexandra de Abreu Serra Marques Pereira (Aggregation)
2021/10/15 Arguente principal nas provas de S.J. Wiersma. Doutoramento em “Industrial Microbiology”, at the Delft University of Technology, sob orientação de J.M.G. Daran e Jack Pronk, com a tese intitulada “Oxygen requirements for lipid biosynthesis in yeast”. 15 outubro 2021.
(Thesis) Main arguer
 S.J. Wiersma (PhD)
Technische Universiteit Delft, Netherlands
2020/10/05 Arguente principal nas provas do Ing. Dominik Jeschek, MSc., "An in vitro assay to analyze the activity of membrane transport proteins", Department für Biotechnologie, Universität für Bodenkultur Wien, sob a orientação do Ass.Prof. Dipl.Natw. ETH FH-Prof. Dr. Michael Sauer.
(Thesis) Main arguer
 Dominik Jeschek (PhD)
2019 Arguente principal nas provas de Ana Cláudia Rodrigues Fonseca. Doutoramento em Biociências, Especialização em Farmácia, Universidade de Lisboa, sob orientção de Graça Soveral, Membrane permeability and aquorporin involvement in oxidative stress and cancer. 17 junho 2019.
(Thesis) Main arguer
 Ana Cláudia Rodrigues Fonseca (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019 Arguente principal nas provas de Maria Fernanda Niño González para prestação de Provas de Doutoramento no ramo de Biociências Moleculares e especialidade de Biologia. ITQB sob orientação de Paula Duque, The Major Facilitator Superfamily (MFS) of membrane transporters: Uncovering novel determinants of plant abiotic stress tolerance. 9 dezembro 2019.
(Thesis) Main arguer
 Maria Fernanda Niño González (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2018 Arguente principal nas provas de Carla Isabel Gomes Gonçalves. Doutoramento em Biologia, Genética Molecular, FCT, Universidade Nova de Lisboa, sob orientação de Paula Gonçalves, “Unravelling the molecular basis of the evolution of fructophily in yeasts: a comparative genomics approach”. 10 de Maio 2018.
(Thesis) Main arguer
 Carla Isabel Gomes Gonçalves (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018 Arguente principal nas provas de Tânia de Jesus Travassos Leandro. Doutoramento em Biociências, Especialização em Microbiologia, Universidade Coimbra, sob orientção de Milton Costa, “Microbial diversity and anaerobic mrtabolisms in the sursurface of the Iberian Pyritic Belt”. 5 Julho 2018.
(Thesis) Main arguer
 Tânia de Jesus Travassos Leandro (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017/10/10 Arguente nas provas de Agregação de Carlos José Manaia Sinogas. 09 e 10 de Outubro de 2017. Universidade de Évora.
(Thesis) Main arguer
 Carlos José Manaia Sinogas (Aggregation)
Universidade de Évora, Portugal
2017/06/27 Arguente nas provas de Agregação de Paula Maria de Melim e Vasconcelos de Vitorino Morais. 26 e 27 Junho 2017. Universidade de Coimbra.
(Thesis) Main arguer
 Paula Maria de Melim e Vasconcelos de Vitorino Morais (Aggregation)
Universidade de Coimbra, Portugal
2017 Arguente principal nas provas de Mara Teresa Caldeira da Silva. Doutoramento em Bioquimica, sob a orientação de Teresa Caldeira, com a tese “Novel Biocides for cultural Heritage”. 29 de Março de 2017, Universidade de Évora.
(Thesis) Main arguer
 Mara Teresa Caldeira da Silva (PhD)
Universidade de Évora, Portugal
2017 External examiner. Katarzyna Niedzwiecka’s doctoral dissertation "Molecular mechanisms of 3-bromopyruvate activity in multiple myeloma cells and pathogenic microorganisms of the genus Cryptococcus and Prototheca" performed at the Institute of Genetics and Microbiology, Faculty of Biological Sciences, University of Wroclaw, under the supervision of prof. dr hab. Stanislaw Ulaszewski. June 2017.
(Thesis) Arguer
 Katarzyna Niedzwiecka (PhD)
Uniwersytet Wroclawski Wydzial Biotechnologii, Poland
2017 Arguente principal nas provas de Soraia Cristina Marques Caetano. Doutoramento em Biologia, Especialidade de Biologia Molecular, ITQB Nova sob a orientação de Claudina Rodrigues-Pousada, com a tese “Stress response mechanisms underlying metal detoxification in yeast”. 25 de julho 2017.
(Thesis) Main arguer
 Soraia Cristina Marques Caetano (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2016/10/11 Arguente nas provas de Agregação de Célia Manaia. 10 e 11 de Outubro 2016. Universidade Católica. Porto.
(Thesis) Main arguer
 Célia Manaia (Aggregation)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2016 Arguente principal nas provas de Cláudia Suellen Ferro de Oliveira. Doutoramento em Patologia e Genética Molecular, ICBAS, sob a orientação de Ana Arminda Lopes Preto de Almeida com a tese “Unraveling the mechanism involved in acetate induced apoptosis in colorectal cancer”. 11 Março 2016. Universidade do Porto.
(Thesis) Main arguer
 Cláudia Suellen Ferro de Oliveira (PhD)
Universidade do Porto, Portugal
2015/06/03 Arguente nas provas de Agregação de Carlos Farinha. 2 e 3 de Junho 2015. FCUL. Lisboa.
(Thesis) Main arguer
 Carlos Farinha (Aggregation)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
2015 Arguente principal nas provas de Cátia Andreia Lourenço Marques. Doutoramento em Ciências Biomédicas, sob orientação de Leonor Cancela e de Vincent Laizé, com a tese “Evolution, gene regulation and functional analysis of BMP2 in fish”. 10 de Fevereiro de 2015. Universidade do Algarve.
(Thesis) Main arguer
 Cátia Andreia Lourenço Marques (PhD)
Universidade do Algarve - Campus de Gambelas, Portugal
2015 Arguente principal nas provas de Sara Isabel Rodrigues dos Santos. Doutoramento em Genética Molecular Comparativa e Tecnológica, UTAD, sob a orientação de Henrique Guedes-Pinto e de Raquel Chaves com a tese “ERBB2 and TWIST1 genes survey in Cat mammary tumours – nucleic acids sequnces and expression changes”. 2 de Março de 2015. UTAD.
(Thesis) Main arguer
 Sara Isabel Rodrigues dos Santos (PhD)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2015 Arguente principal nas provas de Maria Leonor Gonçalves Pereira. Doutoramento em Genética Molecular Comparativa e Tecnológica, UTAD, sob a orientação de Henrique Guedes-Pinto e de Paula Martins-Lopes com a tese “Wine Authenticity – a genomic approach”. 15 dezembro 2015. UTAD.
(Thesis) Main arguer
 Maria Leonor Gonçalves Pereira (PhD)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2014 Arguente nas provas de Sara Cristina Sequeira Alves. Doutoramento em Ciências – especialidade em Biologia, sob orientação de Ana Preto, com a tese “Impact of mutated KRAS signaling on autophagy regulation in colorectal carcinoma”. 12 de Fevereiro de 2014. UMinho.
(Thesis) Main arguer
 Sara Cristina Sequeira Alves (PhD)
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2014 Arguente da tese (OVERSEA EXAMINER) de Michele Bruschi para obtenção do grau de Doctor of Philosophy, University of Queensland, Australian Institute for Bioengineering and Nanotechnology. 31 de Maio de 2014.
(Thesis) Main arguer
 Michele Bruschi (PhD)
The University of Queensland Australian Institute for Bioengineering and Nanotechnology, Australia
2014 Arguente principal nas provas de Fátima Gil. Doutoramento em Biotecnologia, sob orientação de Cristina Viegas e Jorge Leitão, com a tese “Development of bioassays for pesticide toxicity assessment using the eukaryotic models Saccharomyces cerevisiae and Caenorhabditis elegans”. 24 de Julho de 2014. IST, Universidade de Lisboa.
(Thesis) Main arguer
 Fátima Gil (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014 Arguente principal nas provas de Tiago Monteiro Lomba Viana. Doutoramento em Biotecnologia, sob orientação de Catarina Prista, com a tese “In search of role of yeasts regulatory pathways during the late stages of fermentation”. 4 de Setembro de 2014. ISA, Universidade de Lisboa.
(Thesis) Main arguer
 Tiago Monteiro Lomba Viana (PhD)
Universidade de Lisboa Instituto Superior de Agronomia, Portugal
2013 Arguente principal nas provas de Ana Rita Macedo Bezerra. Doutoramento em Biologia, Universidade de Aveiro, sob a orientação de Manuel Santos com a tese “Genómica molecular de uma alteração ao código genético”. 27 fevereiro 2013. Universidade de Aveiro.
(Thesis) Main arguer
 Ana Rita Macedo Bezerra (PhD)
Universidade de Aveiro, Portugal
2013 Arguente principal nas provas de Sandra Louzada Gomes Pereira. Doutoramento em Genética Molecular, Comparativa e Tecnológica, UTAD, sob a orientação de Raquel Chaves e Filomena Adega com a tese “Karyotype restructuring in Rodentia: from evolution to cancer”. 14 maio 2013. UTAD.
(Thesis) Main arguer
 Sandra Louzada Gomes Pereira (PhD)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2013 Arguente principal nas provas de Ana Sofia Cunha. Doutoramento em Bioquímica, Universidade de Coimbra, sob a orientação de Milton Costa, com a tese “Insights on the accumilation and biosynthetic pathway for mannosylglucosylglycerate in the deep-branching phylum Panctomycetes”. 23 outubro 2013. UCoimbra.
(Thesis) Main arguer
 Ana Sofia Cunha (PhD)
Hospitais da Universidade de Coimbra, Portugal
2012/07/17 Arguente nas provas de Agregação de Gilberto Igrejas. 16 e 17 de Julho 2012. UTAD. Vila Real.
(Thesis) Main arguer
 Gilberto Igrejas (Aggregation)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2012/02/07 Arguente nas provas de Agregação de Maria Luísa Lopes de Castro e Brito. 6 e 7 de Fevereiro 2012. Instituto Superor de Agronomia, Universidade Técnica de Lisboa.
(Thesis) Main arguer
 Maria Luísa Lopes de Castro e Brito (Aggregation)
Universidade de Lisboa Instituto Superior de Agronomia, Portugal
2012 Arguente principal nas provas de Stefan de Kok. Doutoramento em “Industrial Microbiology”, at the Delft University of Technology, sob orientação de Ton van Maris and Jack Pronk, com a tese “Metabolic engineering of free-energy (ATP) conserving reactions in Saccharomyces cerevisiae”. 3 de Abril 2012, the Delft University of Technology, Holanda.
(Thesis) Main arguer
 Stefan de Kok (PhD)
Technische Universiteit Delft, Netherlands
2012 Arguente principal nas provas de Doryaneh Ahmadpours. Doutoramento na Faculty Department of Chemistry and Molecular Biology, University of Gothenburg sob a orientação de Stefan Homman e Markus Tamas com a tese “Stress, hoemostasis and robustness - molecular and systems biology level analysis in yeast”. 24 maio de 2012, University of Gothenburg, Suècia.
(Thesis) Main arguer
 Doryaneh Ahmadpours (PhD)
Göteborgs Universitet, Sweden
2012 Arguente principal nas provas de Ben Souffriau. Doutoramento em Bioscience Engineering, University of Leuven, sob a orientação de Ir. F. Delvaux e J. Thevelein com a tese “Transport and metabolism of D-galacturonic acid in the yeast Saccharomyces cerevisiae”. 22 junho de 2012, Bélgica
(Thesis) Main arguer
 Ben Souffriau (PhD)
Université catholique de Louvain Unité de pharmacologie cellulaire et moléculaire, Belgium
2011/07/20 Arguente nas provas de Agregação de Maria da Graça Tavares Rebelo de Soveral Rodrigues. 19 e 20 de Julho 2011. Faculdade de Farmácia da Universidade de Lisboa.
(Thesis) Main arguer
 Maria da Graça Tavares Rebelo de Soveral Rodrigues (Aggregation)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2011 Arguente nas provas de Sílvia Cristina Gomes Pereira. Doutoramento em Engenharia de Tecidos, Medicina Regenerativa e Células Estaminais, com a tese intitulada “Genetically engineered new spider silk chimeras for bone regeneration”, dia 08 de Abril de 2011, Universidade do Minho.
(Thesis) Main arguer
 Sílvia Cristina Gomes Pereira (PhD)
Universidade do Minho - Campus de Azurém, Portugal
2010 Arguente principal nas provas de Catarina Sá Almeida Amaral, Doutoramento em Biologia, com a tese intitulada “Role of Yap8 and Yap1 b-ZIP transcription factors in arsenic stress”. 22 de Janeiro de 2010, Instituto de Tecnologia Química e Biológica da Universidade Nova de Lisboa, Oeiras
(Thesis) Main arguer
 Catarina Sá Almeida Amaral (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2010 Arguente principal nas provas de Artur Magalhães Ribeiro, Doutoramento em Biologia, com a tese intitulada “Functionality development is systems based on elastin-like recombinamers: from nano-objects to macrogels”. 1 de Março de 2010, Universidade de Valladolid
(Thesis) Main arguer
 Artur Magalhães Ribeiro (PhD)
Universidad de Valladolid, Spain
2010 Arguente principal nas provas de Maria Joana Patrício Gonçalves de Sá, Doutoramento em Bioquímica, especialidade Biologia Celular e Molecular, com a tese intitulada “Identification and characterization of a new calcium binding protein from sturgeon, Gal rich protein or GRP. Contribuition to unveil its function in vertebrates”, 16 de Julho de 2010, Universidade do Algarve, Faro
(Thesis) Main arguer
 Maria Joana Patrício Gonçalves de Sá (PhD)
Universidade do Algarve - Campus de Gambelas, Portugal
2010 Arguente principal nas provas de Carla Alexandra São Bento Viegas, Doutoramento em Biologia de Sistemas, com a tese intitulada “Communication and Choice in yeast mating”, 23 de Junho de 2010, IGC, Oeiras, Universidade de Nova de Lisboa
(Thesis) Main arguer
 Carla Alexandra São Bento Viegas (PhD)
Instituto Gulbenkian de Ciência, Portugal
2010 Arguente principal nas provas de Carla Alexandra São Bento Viegas, Doutoramento em Biologia de Sistemas, com a tese intitulada “Communication and Choice in yeast mating”, 23 de Junho de 2010, IGC, Oeiras, Universidade de Nova de Lisboa
(Thesis) Main arguer
 Carla Alexandra São Bento Viegas (PhD)
Instituto Gulbenkian de Ciência, Portugal
2010 Arguente principal nas provas de Margarida Isabel Rosa Bento Palma, Doutoramento em Biologia, com a tese intitulada “Sugar transport in yeast: phylogenetic analysis of sugar porters in the global response to chemical stress”, dia 21 de Dezembro de 2010, FCT, Monte da Caparica, Universidade de Nova de Lisboa.
(Thesis) Main arguer
 Margarida Isabel Rosa Bento Palma (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2009 Arguente principal nas provas de Esperanza López Franco, Doutoramento em Microbiologia, com a tese intitulada “Desacetilasas de Histonas Y Morfogénesis en Candida albicans”, 23 de Janeiro de 2009, Universidade de Salamanca, Espanha
(Thesis) Main arguer
 Esperanza López Franco (PhD)
Universidad de Salamanca, Spain
2008 Arguente principal nas provas de Maria José Leandro, Doutoramento em Biologia, especialidade Biologia Molecular, com a tese intitulada “Molecular characterization of xylose/glucose transport in the yeast Candida intermedia”. 22 de Fevereiro de 2008, Universidade Nova de Lisboa, Faculdade de Ciências e Tecnologia.
(Thesis) Main arguer
 Maria José Leandro (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2008 Arguente principal nas provas de Jorge Augusto Machado Pereira, Doutoramento em Bioquímica, especialidade Bioquímica, com a tese intitulada “Deciphering the role of Yap4 phosphorylation under stress conditions”. 15 de Dezembro de 2008, Instituto de Tecnologia Química e Biológica da Universidade Nova de Lisboa, Oeiras
(Thesis) Main arguer
 Jorge Augusto Machado Pereira (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2006 Arguente principal nas provas de Isabel Miranda, Doutoramento em Biologia, com a tese intitulada “Estudo molecular de uma alteração ao código genético de Cândida albicans”. 21 de Setembro de 2006, Universidade de Aveiro.
(Thesis) Main arguer
 Isabel Miranda (PhD)
Universidade de Aveiro, Portugal
2005 Arguente principal nas provas de Marta Pinheiro Torres Marques, Doutoramento em Ciências Biomédicas, especialidade Bioquímica, com a tese intitulada “Oxidative stress in Saccharomyces cerevisiae: the key role of ISC1p sphingomyelinase in cell resistance, and the molecular mechanisms associated to the recovery from hydrogen peroxyde stress”. 21 de Março de 2005, ICBAS, Universidade do Porto.
(Thesis) Main arguer
 Marta Pinheiro Torres Marques (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2005 Arguente principal nas provas de Célia Maria Jesus Ferreira, Doutoramento em Ciências, ramo Biologia, com a tese intitulada “Identification and characterization of the glycerol/H+ symporter in Saccharomyces cerevisiae and the involvement of related genes in the cell wall integrity”. 11 de Outubro de 2005, Universidade do Minho.
(Thesis) Main arguer
 Célia Maria Jesus Ferreira (PhD)
Universidade do Minho, Portugal
2004 Arguente principal nas provas de Maria Luísa Vieira das Neves, Doutoramento em Ciências, ramo Biologia, com a tese intitulada “Glycerol transport in yeasts: physiological, molecular and phylogenetic approaches”. 15 de Novembro de 2004, Universidade do Minho.
(Thesis) Main arguer
 Maria Luísa Vieira das Neves (PhD)
Universidade do Minho, Portugal

Committee member

Activity description
Role		 Institution / Organization
2010 - 2011 Member of the EU international panel of experts - European Commission DG Research Biotechnologies, Agriculture and Food Horizontal and co-ordination aspects B - 1049 Brussels. Assessment of the Researcg Impact of the EU-Frame Work Program on Research in Biotechnologies, Agriculture and Food. November 2010- March 2011.
Advisor / Consultant

Conference scientific committee

Conference name Conference host
2025/12/04 - 2025/12/06 Scientific committee MicroBiotec´25 Universidade dos Açores
2025/06/05 - 2025/06/06 6th INTERNATIONAL MEETING OF THE PORTUGUESE SOCIETY OF GENETICS – IMPSG 2025. ITQB, Oeiras ITQB. Oeiras
2024/09/20 - 2024/09/21 XXII Jornadas de Biologia de Leveduras Professor Nicolau van Uden. Curia. Portugal
2023/12/07 - 2023/12/09 Scientific committee MicroBiotec´23 Universidade da Beira Interior, Covilhã
2023 - 2023 - Scientific committee and Chair person. 4th INTERNATIONAL MEETING OF THE PORTUGUESE SOCIETY OF GENETICS – IMPSG 2023. UMinho, Braga, 19-20 Outubro, 2023.
2022 - 2022 Scientific committee and Chair person. 3rd INTERNATIONAL MEETING OF THE PORTUGUESE SOCIETY OF GENETICS – IMPSG 2022. UÉvora, Évora, 27-28 Junho, 2022.
2021 - 2021 Scientific committee and Chair person. 2nd INTERNATIONAL MEETING OF THE PORTUGUESE SOCIETY OF GENETICS – IMPSG 2021. UTAD, Vila Real. 1 -2 de Julho, 2021.
2019 - 2019 Chair person – 6th International Society of Cancer Metabolism (IsCam) annual meeting, Cancer metabolic rewiring: mapping the road to clinical translation. Braga, 17-19 Outubro, 2019.
2016 - 2016 Chair person – SMYTE 34 – Small Meeting in Yeast Transport and Energetics, 29 August-1 September, 2016, Crete, Greece.
2016 - 2016 Chair person – PYFF 2016 PYFF6 - Sixth Conference on Physiology of Yeasts and Filamentous Fungi - Session in Transport, Signalling and Intracellular Trafficking. 11-14 July 2016, Lisbon.

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2001 - Current Genética Clássica e Molecular de Leveduras. 30 de Janeiro a 2 de Fevereiro de 2001. Departamento de Biologia da Universidade do Minho. Mestrado de genética Universidade do Minho, Portugal
2024 - 2024 Advanced course Advanced Course on Structural Biology of Membrane Transporters. Coordination: Margarida Casal and Isabel João Silva. Curso de Mestrado em Genética Molecular e Curso Doutoral em Biologia Molecular e Ambiental. UMinho. 2024. Mestrado em Genética Molecular; Mestrado em Bioquímica Aplicada (Pós-Graduação) Universidade do Minho, Portugal
2010 - 2020 Advanced course on Biopolymers based on renewable resources: from synthesis to applications. Post-graduated training programme, Centro de Biologia Molecular e Ambiental da Universidade do Minho (CBMA-UM). Total 60 h, 6 ECTS. Regente do curso e responsável. Edições 2011, 2015, 2016, 2020, 2025 Mestrado em Biofísica e Bionanosistemas, Mestrado em Genética Molecular. (Mestrado) Universidade do Minho, Portugal
2014 - 2014 TRANSPROT - New insights into structure, function and regulation of transport proteins. ERASMUS Intensive programme. Nº 2013-PT1-ERA10-16664. Centro de Biologia Molecular e Ambiental da Universidade do Minho (CBMA-UM). 2 -13 June, 2014. 11 dias de trabalho, 23 h lectures,17 h lab work,14 h theoretical/practical, 9 h seminars. Universidade do Minho, Portugal
2013 - 2014 Genética e Biotecnologia Molecular. Responsável por aulas teóricas e teórico-práticas. 2013/14. Mestrado em Genética Molecular. (Mestrado) Universidade do Minho, Portugal
2002 - 2014 Advanced course on plasma membrane transporters: physiology, genetics and phylogeny. Post-graduated training programme, Centro de Biologia Molecular e Ambiental da Universidade do Minho (CBMA-UM). Total 60 h, 6 ECTS. Regente do curso e responsável pela organização. Aulas teóricas e práticas. Edições: 2002/03. 2006/07. 2009/10. 2011/12. 2013/14. Mestrado em Genética Molecular (Mestrado) Universidade do Minho, Portugal
2007 - 2010 Engenharia Genética. Regente e responsável pelas aulas teóricas e práticas da disciplina do Mestrado em Bioinformática. Ano lectivo 2007/2008, 2008/2009, 2009/2010. Mestrado em Bioinformática (Mestrado) Universidade do Minho, Portugal
2005 - 2010 Biology’s Engineering Principles for Design of Protein-based Machines and Materials. Dan W. Urry, University of Minnesota, EUA, M. Casal (organizer, UMinho). Post-graduated training programme. 24 h teóricas e 6 h práticas. 2005. 2007. 2011. Mestrado em Genética Molecular Universidade do Minho, Portugal
2002 - 2009 Genética e Biotecnologia Molecular. Regente e responsável pelas aulas teóricas e teórico-práticas do módulo Expressão Genética. Anos lectivos 2002/2003, 2004/2005, 2006/2007, 2007/2008, 2008/2009. Mestrado em Genética Molecular (Mestrado) Universidade do Minho, Portugal
2005 - 2007 Genética Molecular. Regente e responsável pelo módulo Bioinformática. Aulas teóricas e práticas. Anos lectivos 2005/2006 e 2006/ 2007. Mestrado em Genética Molecular. (Mestrado) Universidade do Minho, Portugal

Evaluation committee

Activity description
Role		 Institution / Organization Funding entity
2012 - Current Avaliadora do programa de projetos da “International Foundation for Science”, IFS Research Grant Application AF 23447. Abril 2012.
Evaluator
 International Foundation for Science, Sweden
2025 - 2025 Avaliadora científica das candidaturas submetidas à Edição do Programa Promove para a tipologia ‘projetos de I&D mobilizadores’, lançada pela Fundação “la Caixa” em parceria com a FCT. 30 de abril 2025.
Evaluator
2023 - 2024 Colabora com a Agência de Avaliação e Acreditação do Ensino Superior (A3ES) como membro do painel de avaliação dos Mestrados em Microbiologia da Faculdade de Farmácia da UPorto, 2023
Evaluator
2022 - 2024 Avaliadora ECUM – nomeada avaliadora do desempenho de investigadores relativo ao biénio 2022-2023 (art.º 22º do Regulamento de Avaliação do Desempenho do Pessoal Investigador da Escola de Ciências da Universidade do Minho (RAPI EC). 2024.
Evaluator
2014 - 2017 Agência de Avaliação e Acreditação do Ensino Superior (A3ES). Membro do painel de avaliação em Biologia, Bioquímica e Biotecnologia. Edições: 2014, 2015, 2016, 2017.
Evaluator
 Agência de Avaliação e Acreditação do Ensino Superior , Portugal Agência de Avaliação e Acreditação do Ensino Superior
2013 - 2017 Membro do Supervisory Board do YEASTCELL ITN project, Irlanda 2013-17.
Specialist
 University College Cork National University of Ireland University College Cork Boole Library, Ireland University College Cork National University of Ireland University College Cork Boole Library
2014 - 2016 Membro da Comissão de Avaliação de Relatórios Finais da área da Biologia Experimental, coordenada pela Professora Cecília Rodrigues. Edições: 2014, 2015, 2016.
Evaluator
 Fundação para a Ciência e a Tecnologia, Portugal Fundação para a Ciência e a Tecnologia
2014 - 2014 Avaliadora de projetos do Programa AgreenSkills & AgreenSkills+ um program de bolsas post-dos co-financiado pela União Europeia e o INRA (França), em colaboração com instituições de ensino superior (www.agreenskills.eu). 2014.
Evaluator
 AgroParisTec Microbiologie et génétique moléculaire, France AgroParisTec Microbiologie et génétique moléculaire
2012 - 2012 Membro da Comissão de Avaliação de Recursos da área das Ciências Biológicas FCT-2010, coordenada pelo Professor Nuno Ferrand. Janeiro de 2012.
Evaluator
 Fundação para a Ciência e a Tecnologia, Portugal Fundação para a Ciência e a Tecnologia
2010 - 2012 Membro do painel de avaliação das candidaturas ao “Concurso para Atribuição de Bolsas Individuais de Doutoramento e Pós-Doutoramento – na área das Ciências Biológicas”. Edições: 2010. 2011. 2012
Evaluator
 Fundação para a Ciência e a Tecnologia, Portugal Fundação para a Ciência e a Tecnologia
2011 - 2011 Avaliadora do programa de projetos de investigação. Université Libre de Bruxelles (ULB),2012-2017 programme, a convite de Prof. Pierre Marage, Vice-Rector for Academic Policy and Research & Dr. Daniele Carati, Head of the Research Department, ULB. Outubro 2011.
Specialist
 Université Libre de Bruxelles, Belgium Université Libre de Bruxelles
2011 - 2011 Membro da Comissão de Avaliação de Recursos da área das Ciências Biológicas FCT-2009, coordenada pelo Professor Nuno Ferrand. Março de 2011.
Evaluator
 Fundação para a Ciência e a Tecnologia, Portugal Fundação para a Ciência e a Tecnologia
2010 - 2010 Membro da Comissão de Avaliação de Recursos da área das Ciências Biológicas FCT –2007, coordenada pelo Professor Nuno Ferrand. Agosto de 2010.
Evaluator
 Fundação para a Ciência e a Tecnologia, Portugal Fundação para a Ciência e a Tecnologia
2009 - 2009 Avaliação de Projectos de Intercâmbio na área das Ciências Biológicas FCT – 2009, coordenada pelo Professor Manuel Santos. 2009.
Evaluator
 Fundação para a Ciência e a Tecnologia, Portugal Fundação para a Ciência e a Tecnologia
2008 - 2008 Avaliação de projectos da Agência de Inovação, Portugal. Julho de 2008.
Evaluator
 Agência Nacional de Inovação SA, Portugal Agência Nacional de Inovação SA
2008 - 2008 Membro da Comissão de Avaliação de Recursos da área das Ciências Biológicas FCT – 2006, coordenada pelo Professor Arsélio Pato de Carvalho e sub-coordenada pelo Professor Carlos Duarte. Agosto de 2008.
Evaluator
 Fundação para a Ciência e a Tecnologia, Portugal Fundação para a Ciência e a Tecnologia
2007 - 2007 Avaliadora do Grantová Agentura Ceské Republiky, Czech Science Foundation, (Registration No.:15/05/2007 Chemistry 203/08/J005). República Checa. 2007.
Evaluator
 Grantová agentura Ceské republiky, Czech Republic Grantová agentura Ceské republiky
2005 - 2006 Membro do Comité de Avaliação de Tecnologias (CAT) do programa Programa TecValor – Valorização de Tecnologias lançado pelo Vice-Reitor Prof. Doutor Manuel Mota, responsável pelo pelouro da Investigação Científica e Extensão Universitária, e que visou dinamização da política de valorização do conhecimento da Universidade do Minho.
Evaluator
 Universidade do Minho, Portugal Universidade do Minho

Journal scientific committee

Journal title (ISSN) Publisher
2021/01/01 - 2023/04/04 Special Issue Editor of Special Issue on "Fungi Nutrient Transportation" (https://www.mdpi.com/journal/jof/special_issues/nutrient_transportation) (https://www.mdpi.com/journal/jof/special_issues/nutrient_transportation)
Distinctions

Award

2023 Prize for Best Poster Communication , 8th Conference on Physiology of Yeasts and Filamentous Fungi: Fungal Oligopeptide Transporters among fungi. reflects their complex evolutionary history. Becerra C, Casal M, Paiva S, Galeote V and Devillers H.
Federation Of European Microbiological Societies, Netherlands
2023 Prize for Best Poster Communication- Unravelling the molecular mechanisms behind pH-induced downregulation of a lactate nutrient transporter”. Barata-Antunes C, de Hulster E, Fernandes V, Cardoso C, Ribeiro IP, Diallinas G, Casal M, Gerós H, Ariño J, Mans
Sociedade Portuguesa de Genética, Portugal
2020 Prémio de melhor comunicação em painel. 3-bromopyruvate boosts the effect of chemotherapy in acute myeloid leukaemia by reducing cell antioxidant defence. Cancer Biology: from basic to translational research
Liga Portuguesa Contra o Cancro, Portugal
2019 Best Poster - Barbosa, A.M., Cunha, A., Casal, M., Queirós, O. 2019 Comparison of 3-bromopyruvate effect in a parental and resistant breast cancer cell line. XI Jornadas Científicas do Instituto Universitário de Ciências da Saúde
2016 Best Oral communication - Alves R, Mota S, Silva S, Rodrigues CF, Brown A J, Henriques M, Casal M & Paiva S. Lactic acid increases the susceptibility of Candida albicans to fluconazole. XIX National Congress of Biochemistry
2015 Best Poster - Silk-based polymers functionalized with fibronectin type-II for improved cell adhesion
Sociedade Portuguesa de Genética, Portugal
2013 Editor’s pick in Biomedical Materials - The article “Electrospun silk-elastin-like fibre mats for tissue engineering applications” was chosen as an Editor’s Pick in 2013.
2012 The team was awarded for the publication: Butyrate activates the monocarboxylate transporter MCT4 expression in breast cancer cells and enhances the antitumor activity of 3-bromopyruvate. Journal of Bioenergetics and Biomembranes 44, 141-153
2011 Nature Cell Biology Poster Prize, 2011 - "Ubiquitin and ubiquitin-like modifiers: from functional modules to systems biology”.
2010 1º Prize"SpinUM" - entrepreneurship contest to the idea "NanoBiodelivery".
Universidade do Minho, Portugal
2009 MICRO/BIOTEC´09 - Best poster- “The lactate permease from Saccharomyces cerevisiae and the lactose permease from Esch
Sociedade Portuguesa de Microbiologia, Portugal
2008 MICRO/BIOTEC´08 - Best Work - Prémio simpósio “Biotechnologia Ambiental”
Sociedade Portuguesa de Microbiologia, Portugal

Other distinction

2023 Editor Choice 2023 was attributed to the work "Uncovering Novel Plasma Membrane Carboxylate Transporters in the Yeast Cyberlindnera jadinii" - Journal of Fungi
2022 Cover Issue - selected paper “Interactions of cytosolic termini in the major facilitator superfamily member Jen1 are critical for trafficking and transport activity” https://doi.org/10.1242/jcs.260059
2021 The paper entitled "Expanding the Knowledge on the Skillful Yeast Cyberlindnera jadinii"in /J. Fungi/. https://www.mdpi.com/2309-608X/7/1/36 was been selected to be featured issue cover (Volume 7, Issue 1: https://www.mdpi.com/2309-608X/7/1).
2020 Prémio de reconhecimento- Internacional Microorganism Day -new article on Federation of European Microbiological Societies FEMS - On International Microorganism Day new article by the researcher M. Casal team, was highlighted on the web
2017 Member of the Directive Board of the Sociedade Portuguesa de Bioquímica (Vogal) 2017/19
Sociedade Portuguesa de Bioquímica, Portugal
2012 Elected Vice-President of the Portuguese Society of Genetics - 2012/14- 2015/17 - 2017/19
Sociedade Portuguesa de Genética, Portugal
2010 Elected President of the Portuguese Society of Genetics - June 2010/ June 2012
Sociedade Portuguesa de Genética, Portugal
1993 FEBS Short Term Fellowship. Instituto de Investigaciones Biomédicas, Madrid, Espanha. Supervised by Prof. Doutor Carlos Gancedo. 1 September - 30 October 1993.
1992 EMBO Short Term Fellowship. Instituto de Investigaciones Biomédicas, Madrid, Espanha. Supervised by Prof. Doutor Carlos Gancedo, 1 September - 30 October 1992.