Identification
Personal identification
- Full name
- Rune Matthiesen
Citation names
- Matthiesen, Rune
Author identifiers
- Ciência ID
- BB1A-A606-EE77
- ORCID iD
- 0000-0002-6353-2616
Knowledge fields
- Natural sciences - Biological Sciences - Biochemistry
- Exact Sciences - Computer and Information Sciences - Bioinformatics
- Medical and Health Sciences - Medical Biotechnology
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
Danish (Mother tongue) | |||||
English | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) |
German | Upper intermediate (B2) | Proficiency (C2) | Upper intermediate (B2) | Proficiency (C2) | Intermediate (B1) |
Portuguese | Intermediate (B1) | Intermediate (B1) | Beginner (A1) | Intermediate (B1) | Intermediate (B1) |
Education
Degree | Classification | |
---|---|---|
2000/12/31 - 2003/12/16
Concluded
|
Departmen of Life Science, University of Aalborg (Doutoramento)
Aalborg Universitet, Denmark
"Mass spectrometry in Proteomics" (THESIS/DISSERTATION)
|
|
1998/07/01 - 1999/07/01
Concluded
|
Molecular biology (Mestrado)
Aarhus Universitet, Denmark
"Crystallography of ternary complex of eIF2" (THESIS/DISSERTATION)
|
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2016/08/01 - Current | Principal Investigator (Research) | iNOVA4Health, Portugal |
2013/08/01 - 2016/08/01 | Principal Investigator (Research) | Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal |
Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal | ||
2008/08/01 - 2013/08/01 | Principal Investigator (Research) | Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal |
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal | ||
2006/01/01 - 2008/08/01 | Principal Investigator (Research) | CIC bioGUNE, Spain |
CIC bioGUNE, Spain | ||
2004/01/01 - 2006/01/01 | Auxiliary Researcher (Research) | Syddansk Universitet, Denmark |
Syddansk Universitet, Denmark | ||
2004/01/01 - 2005/01/01 | Auxiliary Researcher (Research) | European Bioinformatics Institute, United Kingdom |
European Bioinformatics Institute, United Kingdom |
Projects
Grant
Designation | Funders | |
---|---|---|
2022/10/01 - 2025/10/01 | Centre for Excellence in Diagnostic and Advanced Therapeutics based on Extracellular Vesicles (EVCA)
Coordinator
Universidade Nova de Lisboa, Portugal
|
EU Framework Programme for Research and Innovation Euratom
Ongoing
|
2022/10 - 2025/10 | Centre for Excellence in Diagnostic and Advanced Therapeutics based on Extracellular Vesicles (EVCA)
Coordinator
|
EU Framework Programme for Research and Innovation Euratom
Cancelled
|
2022/01/17 - 2025/01/17 | Optimizing mass spectrometry based detection of biomarkers for immunotherapy response across urologic cancers
PTDC/BTM-TEC/1746/2021
Principal investigator
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2019/01 - 2022/12 | Immune- and microenvironment- proteogenomics profiling for classifying lung cancer patients | Science and Technology Foundation |
2019/01 - 2022/12 | Impact of B-cell deregulated pathways on tumor immune evasion - relevance for Diffuse Large B-Cell Lymphoma therapy response | Science and Technology Foundation |
2021/06/01 - 2022/06/01 | How could we predict Intraductal and Cribriform Prostate Cancer in Prostate Biopsies?
a2018775d
Researcher
|
Liga Portuguesa Contra o Cancro
Ongoing
|
2018/01 - 2021/12 | UBICODE | _H2020 |
Contract
Designation | Funders | |
---|---|---|
2018/10/01 - 2022/09/30 | Implementação de um teste de diagnóstico para avaliação clínica de doentes com cancro do pulmão com base na análise proteómica
das características imunológicas e do micro-ambiente do tumor.
PTDC/BTM-TEC/30088/2017
Universidade Nova de Lisboa, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2018/10/01 - 2022/09/30 | Sodium-iodide symporter posttranslational interactome: identification of novel targets to enhance iodide-related cancer therapy
PTDC/BIA-MOL/31787/2017
Associação para a Investigação e Desenvolvimento da Faculdade de Medicina, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2018/10/01 - 2021/09/30 | Diffuse Large B-cell lymphoma blood based proteome signatures
PTDC/BTM-TEC/30087/2017
Universidade Nova de Lisboa, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2016/06/01 - 2019/12/31 | ProbeCOPD. Protease activity-based probes for Chronic Obstructive Pulmonary Disease diagnostics
PTDC/BBB-BEP/2463/2014
Associação para a Investigação e Desenvolvimento da Faculdade de Medicina, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2014/03/01 - 2015/06/30 | Identificação global por Espectrometria de Massa de aspirados bronquiais: visando modificações específicas do cancro do pulmão.
EXPL/DTP-PIC/0616/2013
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2010/06 - 2013/11 | Molecular and nanotechnology-based approaches to improve the antitumor activity of small molecules
PTDC/SAU-FCF/100930/2008
Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal Cooperativa de Ensino Superior Politécnico e Universitário CRL, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2011/01/01 - 2012/12/31 | Projecto Estratégico - LA 3 - 2011-2012
PEst-C/SAU/LA0003/2011
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
Other
Designation | Funders | |
---|---|---|
2016/06 - 2021/02/28 | Implications of Medical Low Dose Radiation Exposure
Invited Scientist Fellow
|
Ongoing
|
Outputs
Publications
Book |
|
Conference abstract |
|
Conference paper |
|
Conference poster |
|
Journal article |
|
Preprint |
|
Other
Other output |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2021/02/13 | From lung cancer to prostate cancer | CAncer Prostate Consortium of India ( CAPCI) meeting
CAncer Prostate Consortium of India (Birla Institute of Scientific Research (BISR), India, India)
|
2020/12/18 | R package for proteome quality control of extracellular vesicles | First Workshop of the Portuguese Network on Extracellular Vesicles
IPATIMUP (Porto)
|
2019/02/26 | Proteostasis factors in cancer exosomes | druggability of the ubiquitin system
CEDOC (Lsibon, Portugal)
|
2019/02/15 | Cancer diagnostic potential of exosome proteome | Invited presentation
IMM, Lisbon (Lisbon)
|
2018/04/16 | Diagnostic potential of exosome proteome | BIOSAM
University of Lisbon (Lisbon)
|
2018/02/18 | Bioconductor R package for Proteostasis factors | UBICODE
University of Toulouse (Toulouse, France)
|
Supervision
Thesis Title Role |
Degree Subject (Type) Institution / Organization |
|
---|---|---|
2020/12/31 - 2024/01/01 | Artifical agents in Metabolomics
Supervisor
|
iNOVA4Health - Programme in Translational Medicine, Universidade Nova de Lisboa – NMS|FCM (PhD)
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
|
2020/01/01 - 2024/01/01 | Microenvironment, the shelter of brain malignancies: bidirectional communication between glia and brain tumors
Co-supervisor
|
iNOVA4Health - Programme in Translational Medicine, Universidade Nova de Lisboa – NMS|FCM (PhD)
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
|
2020/01/01 - 2024/01/01 | Urine extracellular vesicle proteome for classification of cribriform and intraductal patterns
Supervisor
|
BioMedicine (PhD)
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
|
2019/12/01 - 2023/01/01 | Urinary proteomics: new insights in overac$ve bladder syndrome
Supervisor
|
BioMedicine (PhD)
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
|
2019/01/01 - 2023/01/01 | Identification of therapeutic targets and disease biomarkers for mutant KRAS cancer patients: fulfilling an unmet clinical
need
Co-supervisor
|
Oncology (PhD)
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
|
2019/01/01 - 2022/01/01 | Correlation of phospho protein network in immune and cancer cells from patients with clinical outcome
Supervisor
|
BioMedicine (PhD)
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
|
2019/01/01 - 2022/01/01 | Ubiquitin proteasome system in cancer and immune cells of patients with Diffuse Large B-Cell Lymphoma (DLBCL)
Supervisor
|
Biomedicine (PhD)
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
|
2019/01/01 - 2020/12/18 | Diffuse Large B-cell Lymphoma current classification based extracellular vesicle proteome
Supervisor
|
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
|
Event organisation
Event name Type of event (Role) |
Institution / Organization | |
---|---|---|
2019/02/26 - 2019/02/28 | druggability of the ubiquitin system (2019/02/26 - 2019/02/28)
Conference (President of the Organising Committee)
|
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal |
2016/11/07 - 2016/11/09 | Proteostasis cost action meeting (2016/11/07 - 2016/11/09)
Conference (President of the Organising Committee)
|
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal |
Jury of academic degree
Topic Role |
Candidate name (Type of degree) Institution / Organization |
|
---|---|---|
2022/07/28 | Study of the protein cargo of extracellular vesicles released by Acute Myeloid Leukemia cell lines
(Thesis) Arguer
|
Inês Adriana Miranda (PhD)
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
|
2020/12/19 | Extracellular vesicles: agents of gut communication in prediabetes scenario
(Thesis) Arguer
|
Ines Antunes Ferreira (PhD)
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
|
2020/12/18 | VENCODE – A VERSATILE ENTRY CODE FOR POST-DNA DELIVERY IDENTIFICATION OF TARGET CELLS
(Thesis) Arguer
|
André Macedo (PhD)
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
|
2019/11/03 | Studying extracellular vesicles from P-glycoprotein overexpressing multidrug resistant cells: New insight into their cargo
and release
(Thesis) Arguer
|
Diana Sousa (PhD)
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
|
2019/03/06 | Multi-omics Integration for Biomarker Discovery
(Thesis) Arguer
|
Marc Clos Garcia (PhD)
CIC bioGUNE, Spain
|
2019/01/27 | REGULATION OF THE RP- MDM2-P53 PATHWAY BY SUMO
(Thesis) Arguer
|
Ahmed Hassan El Motiam (PhD)
Universidade de Santiago de Compostela, Spain
|
2017/06/20 | The Endoplasmic Reticulum Quality Control: Dissecting Protein
Networks in Cystic Fibrosis
(Thesis) Arguer
|
Sara Canato (PhD)
Universidade de Lisboa, Portugal
|
2017 | Methods to compare the proteome of the parasite Trypanosome brucei isolated from two different tissues of its host
(Thesis) Main arguer
|
Mariana Sequeira (PhD) |
2017 | Mass spectrometry-based proteomic strategies to define protein NEDDyation
(Thesis) Main arguer
|
Sofia Celeste Lobato (PhD)
CIC bioGUNE, Spain
|
Association member
Society Organization name | Role | |
---|---|---|
2023/06/01 - Current | Vice president of Portuguese network of extracellular vesicles | accounting |
2018/01/01 - 2022/01/01 | UBICODE https://euraxess.ec.europa.eu/jobs/277683 | Memeber |
2014/01/01 - 2019/01/01 | Proteostasis | National representative |
Committee member
Activity description Role |
Institution / Organization | |
---|---|---|
2024/01/01 - Current | ISEV EV-TRACK task force member working group 3 focusing on outreach and future developments
Member
|
|
2022/10/01 - 2025/10/10 | Coordinator of EVCA board for internal funded EVCA projects.
Coordinator
|
Universidade NOVA de Lisboa NOVA Medical School, Portugal |
2023/01/28 - 2023/01/29 | Coordinator of extracellular vesicles in clinical applications (EVCA) kick off meeting, Ericeia, Portugal
Coordinator
|
|
2020/09/01 - 2023/01/01 | Editor on the journal Cancers
Member
|
Conference scientific committee
Conference name | Conference host | |
---|---|---|
2024/05/07 - 2024/05/10 | Scientific advisory board in ProteoCure meeting in Warsaw Poland | Warsaw Poland |
2023/11/24 - 2023/11/24 | Workshop on arginine methylation extracellular vesicles and cancer | Nova medical school, Lisbon |
2023/06/01 - 2023/06/03 | Organiser of Portuguese Network on Extracellular Vesicles (PNEV) meeting | Nova medical school, Lisbon |
2019/03/26 - 2019/03/29 | druggability of the ubiquitin system | CEDOC |
2016/11/07 - 2016/11/09 | Proteostasis cost action meeting | CEDOC |
Consulting
Activity description | Institution / Organization | |
---|---|---|
2024/01/01 - 2025/01/01 | External consultant Mursla, Cambridge. |
Course / Discipline taught
Academic session | Degree Subject (Type) | Institution / Organization | |
---|---|---|---|
2020/01/01 - Current | Cofounder of master program and responsible for advanced metabolomics and proteomcis course. | MSc in Computational Biology and Bioinformatics (MCBBI) (Mestrado) | Universidade Nova de Lisboa, Portugal |
Evaluation committee
Activity description Role |
Institution / Organization | Funding entity | |
---|---|---|---|
2020/12/01 - Current | The Hellenic Foundation for Research and Innovation (HFRI)
Evaluator
|
||
2022/10/01 - 2025/10/01 | Coordinator of twining project “Centre for Excellence in Diagnostic and Advanced Therapeutics based on Extracellular Vesicles” | Universidade NOVA de Lisboa NOVA Medical School, Portugal | |
2022/01/01 - 2022/01/02 | GrantsUKRI, University of Oxford | University of Oxford - Old Road Campus, United Kingdom | |
2011/01/01 - 2020/01/01 | Evaluator and rapporteur of national projects submitted to the research council of Romania (bioinformatics, proteomics and
clinical projects) and evaluator for the national BrainMap investigator program.
Evaluator
|
uefiscdi.gov.ro | |
2009/01/01 - 2020/01/01 | Evaluator of Spanish National projects (MEC projects)
https://www.mineco.gob.es/evalua/jsp/menu/menu.do?operacion=pintaMenu
Evaluator
|
Ministerio de Ciencia E innovacion, Spain | |
2018/05/16 - 2018/06/30 | Remote and local evaluation of H2020 projects. H2020 Framework program, Brussels, Belgium
Evaluator
|
_H2020, Denmark | EU Framework Programme for Research and Innovation Euratom |
2016/01/01 - 2016/06/01 | Bilateral Scientific Cooperation China" application to the Research Foundation Flanders
Evaluator
|
||
2014/01/01 - 2014/03/01 | Czech-Norwegian Research Programme (CZ09)
Evaluator
|
||
2013/01/01 - 2013/03/01 | Evaluator of FCT investigators
Evaluator
|
||
2010/01/01 - 2010/03/01 | EU INDIGO projects in the area of biomarker discovery, bioinformatics and proteomics
Evaluator
|
Distinctions
Award
2023 | Prémio SPAVC/ Stroke Biomarkers |
2021 | Urinary EV proteomics can we distinguise cribriform and intraductral carcinoma of the prostate |
2020 | Molecular Characterization of Intraductal and Cribriform Prostate Cancer: The future of Exosomes as Biomarkers
Associação Portuguesa de Urologia, Portugal
|
2020 | Urinary extracellular vesicle proteomics |
2019 | CEEC position (FCT); https://doi.org/10.54499/CEECIND/03906/2017/CP1421/CT0004
Fundação para a Ciência e a Tecnologia, Portugal
|
2016 | SPP/ Pfizer Vaccines |
2013 | FCT investigator
Fundação para a Ciência e a Tecnologia, Portugal
|
2008 | Ciencia
Fundação para a Ciência e a Tecnologia, Portugal
|
2006 | Ramón y Cajal (RYC) |
2004 | Carlsberg foundation
Carlsbergfondet, Denmark
|