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Tânia Morais is an junior researcher at Centro de Química Estrutural of Faculdade de Ciências da Universidade de Lisboa (CQE-FCUL). She obtained her degree in Chemistry (2007) by Faculdade de Ciências da Universidade de Lisboa (FCUL), where she also completed a master's degree in Chemistry with specialization in Chemistry, Health and Nutrition (2008). Tânia Morais got her PhD in Chemistry with specialization in Inorganic Chemistry (2013) by University of Lisbon developing ruthenium organometallic compounds for cancer therapy. In 2013 she start a postdoc at Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa and Centro de Química Estrutural, Faculdade de Ciências da Universidade de Lisboa, where she develops peptide-metal conjugates for targeted therapy. In 2014 she was honored by the Portuguese Chemical Society with the prize "Portuguese Young Chemist Award". In 2015, Tânia was a visitor postdoc researcher at Barcelona Biomedical Research Park (PRBB), Barcelona, Spain under a Marie Sklodowska-Curie project, that allow her to acquire important know-how in peptide synthesis. In 2019, Tânia won a contract in the frame of CEEC Individual 2017 program and started an independent research at CQE-FCUL where she develops smart metal-peptide conjugates for targeted therapy, merging her know-how in organometallic chemistry with her expertise in peptide chemistry. Tânia research focuses on the design, synthesis and characterization of Ru, Fe and Cu complexes with targeting molecules (e.g. peptides, carbohydrates, biomolecules) in their structure for the selective inhibition of the cancer development and metastases. Tânia Morais is co-founder of a FCUL proto-company named "HATIcancer". Tânia is currently Principal Investigator of one research project funded by the Portuguese Foundation for Science and Technology (FCT) and she also currently participates on the Transnational Cooperation Programme - Portugal-Hungary, "Development and bio-speciation studies of antitumor ruthenium complexes". Tânia has experience as a scientific adviser (PhD Supervision: 1 (since 2018, ongoing); Master Supervision: 4 (since 2015); Graduation Thesis Supervision: 10 (1 ongoing); Erasmus - graduation students: 2). She is currently a lecturer of the practical course of inorganic complementary chemistry (laboratory classes; BSc in chemistry) and a lecturer Applications of Inorganic Chemistry in Everyday Life (theoretical and theoretical-practical classes; BSc in Chemistry). Tânia has so far authored 33 articles published in international journals with peer review (10 as senior corresponding author), 6 book chapters, several conference proceedings and 4 inter-/national patents with over 715 citations and has a H-index of 16.
Identification

Personal identification

Full name
Tânia Sofia Ferreira Morais
Gender
Female

Citation names

  • Tânia S. Morais
  • T. S. Morais
  • Morais, Tânia S.
  • Morais, T. S.

Author identifiers

Ciência ID
B61A-A9D4-08CC
ORCID iD
0000-0003-0233-8243
Google Scholar ID
https://scholar.google.pt/citations?user=mp1D9D4AAAAJ&hl=pt-PT&oi=ao
Researcher Id
D-8824-2011
Scopus Author Id
25930490800

Email addresses

  • tsmorais@fc.ul.pt (Professional)

Telephones

Telephone
  • 217500954 (Professional)

Addresses

  • Centro de Química Estrutural (CQE@ciências) Faculdade de Ciências da Universidade de Lisboa, Campo Grande, Ed. C8, 1749-016, Lisboa, Lisboa, Portugal (Professional)

Websites

  • https://cqe.tecnico.ulisboa.pt/members/556 (Scholar)
  • https://ciencias.ulisboa.pt/pt/perfil/tsmorais (Scholar)
  • https://www.arrows2cancer.com/ (Professional)
  • https://publons.com/researcher/1604867/tania-s-morais/ (Professional)

Knowledge fields

  • Exact Sciences - Chemical Sciences - Inorganic Chemistry
  • Medical and Health Sciences - Basic Medicine - Medicinal Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Elementary (A2) Upper intermediate (B2) Elementary (A2) Advanced (C1) Elementary (A2)
Education
Degree Classification
2013/12/11
Concluded
Química (Doutoramento)
Major in Química Inorgânica/Inorganic chemistry
Universidade de Lisboa Faculdade de Ciências, Portugal
"Evaluation of the potential anti-tumoral properties of new ruthenium bioorganometallic compounds" (THESIS/DISSERTATION)
20-Aproved by unanimity (summa cun laude)
2008/07
Concluded
Química (Mestrado)
Major in Química, Saúde e Nutrição /Chemistry, health and nutrition
Universidade de Lisboa Faculdade de Ciências, Portugal
"Synthesis and characterization of cytotoxic organometallic complexes derived from “RuCp” fragment and evaluation of their potential as antitumor agents " (THESIS/DISSERTATION)
17
2007/09
Concluded
Química (Licenciatura)
Major in n/a
Universidade de Lisboa Faculdade de Ciências, Portugal
"Synthesis and characterization of Ru(II) and Fe(II) complexes with nitrogenous ligands. Preliminary study on their potential as antitumor agents" (THESIS/DISSERTATION)
15
Affiliation

Science

Category
Host institution
Employer
2019/05/01 - Current Contracted Researcher (Research) Universidade de Lisboa Faculdade de Ciências, Portugal
Universidade de Lisboa Centro de Química Estrutural, Portugal
2016/08/01 - 2019/04/30 Postdoc (Research) Universidade de Lisboa Faculdade de Ciências, Portugal
Universidade de Lisboa Centro de Química Estrutural, Portugal
(...)
2014/03/01 - 2016/07/31 Postdoc (Research) Universidade de Lisboa Faculdade de Medicina, Portugal
Instituto de Medicina Molecular, Portugal
(...)
2015/04/01 - 2015/10/31 Visiting Researcher (Research) Universitat Pompeu Fabra, Spain
Parc de Recerca Biomèdica de Barcelona, Spain

Teaching in Higher Education

Category
Host institution
Employer
2019 - Current Assistant Professor (University Teacher) Universidade de Lisboa Faculdade de Ciências, Portugal
Universidade de Lisboa Faculdade de Ciências, Portugal
2016 - 2018 Invited Assistant Professor (University Teacher) Universidade de Lisboa, Portugal
2013 - 2016 Assistant Professor (University Teacher) Universidade de Lisboa Faculdade de Ciências, Portugal

Positions / Appointments

Category
Host institution
Employer
2020/07 - Current Co-coordinator of the 1st cycle Chemistry Universidade de Lisboa Faculdade de Ciências, Portugal
2020/07 - Current Member of the Pedagogic Committee of the 1st Cycle in Chemistry Universidade de Lisboa Faculdade de Ciências, Portugal

Others

Category
Host institution
Employer
2017/01/22 - Current Co-founder of HATICancer Proto-Company Universidade de Lisboa Faculdade de Ciências, Portugal
2013/12/01 - 2014/02/28 Research Fellow under the project "Preclinical evaluation of ruthenium potential drugs for cancer therapy", FCT PTDC/QUI-QUI/118077/2010 Universidade de Lisboa Faculdade de Ciências, Portugal
2009/11/01 - 2013/10/31 PhD. Student with Fundação para a Ciência e Tecnologia (FCT) grant: SFRH/BD/ 45871/2008 "Evaluation of the potential anti-tumoral properties of new ruthenium bioorganometallic compounds"; Universidade de Lisboa Faculdade de Ciências, Portugal
Universidade de Lisboa Faculdade de Ciências, Portugal
2009/05/01 - 2009/10/31 Research Fellow under the project "Synthesis of molecular and polymeric organometallic materials with non-linear optical properties", FCT PTDC/QUI/66148/2006 Universidade de Lisboa Faculdade de Ciências, Portugal
Universidade de Lisboa Faculdade de Ciências, Portugal
2008/05/01 - 2009/04/30 Research Fellow under the project "Design of copper, zinc or iron compounds with leishmanicidal activity", FCT PTDC/QUI/72656/2006 Universidade de Lisboa Faculdade de Ciências, Portugal
Universidade de Lisboa Faculdade de Ciências, Portugal
2007/10/01 - 2008/04/30 Research in the frame of the M.Sc. thesis in Chemistry: Chemistry, health and nutrition Universidade de Lisboa Faculdade de Ciências, Portugal
Projects

Grant

Designation Funders
2018 - Current Targeting metastatic breast cancer with innovative ruthenium-peptide conjugates
SFRH/BD/135915/2018
Supervisor
Universidade de Lisboa Centro de Química Estrutural, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2014 - 2019/04/30 Targeting tumors with innovative metal peptide complexes: improving efficacy in anticancer drugs
SFRH/BPD/93513/2013
Post-doc Fellow
Instituto de Medicina Molecular, Portugal

Universidade de Lisboa Centro de Química Estrutural, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2009 - 2013/10/31 EVALUATION OF THE POTENTIAL ANTI-TUMORAL PROPERTIES OF NEW RUTHENIUM BIOORGANOMETALLIC COMPOUNDS
info:eu-repo/grantAgreement/FCT/SFRH/SFRH2%FBD2%F458712%F2008/PT
PhD Student Fellow
Universidade de Lisboa Faculdade de Ciências, Portugal

Universidade de Lisboa Centro de Química Estrutural, Portugal
Universidade do Algarve Faculdade de Ciências e Tecnologia
Concluded

Contract

Designation Funders
2019 - Current Ruthenium-peptide drugs: new bullets to fight breast cancer; CEECIND2017 - Stimulus of Scientific Employment -Individual Support 2017 - FCT Programme
CEECIND/00630/2017
Principal investigator
Universidade de Lisboa Centro de Química Estrutural, Portugal

Universidade de Lisboa Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2021 - 2024/02/29 Ruthenium-peptide conjugates: arrows for selectively targeting breast cancer
PTDC/QUI-QIN/0146/2020
Principal investigator
Universidade de Lisboa Centro de Química Estrutural, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2015 - 2015/10/31 Innovative peptides against cancer and pathogenic bacteria, with advances in science, biopharmaceutical drug development, product market targeting, training, and communication
INPACT Grant Agreement: 644167
Researcher
Instituto de Medicina Molecular, Portugal
EU Framework Programme for Research and Innovation Euratom
Concluded
2013 - 2014/02/28 Preclinical evaluation of ruthenium potential drugs for cancer therapy
PTDC/QUI-QUI/118077/2010
Research Fellow
Universidade de Lisboa Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010 - 2013 Ruthenium complexes for anti-tumour applications
PTDC/QUI-QUI/101187/2007
Researcher
Universidade de Lisboa Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2009 - 2009/10/31 Synthesis of molecular and polymeric organometallic materials with non-linear optical properties
PTDC/QUI/66148/2006
Research Fellow
Universidade de Lisboa Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2008 - 2009/04/30 Design of copper, zinc or iron compounds with leishmanicidal activity
PTDC/QUI/72656/2006
Research Fellow
Universidade de Lisboa Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2019 - 2021/05/31 Development and bio-speciation studies of ruthenium anti-tumor complexes _Scientific and Technological Cooperation Project - Portugal-Hungary
FCT/NKFIH, 2019/2020
Researcher
Universidade de Lisboa Centro de Química Estrutural, Portugal

Universidade de Lisboa Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2016 - 2017 Complexes of Flavonoid's Schiff bases: Impact of structural modification on the chelating ability and evaluation of biological and therapeutic properties_Transnational Cooperation Programme - Portugal-Poland
FCT RD0480/Project 6818
Researcher
Universidade de Lisboa Faculdade de Ciências, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Andreia Valente; Tânia S. Morais; Ricardo G. Teixeira; Cristina P. Matos; Ana Isabel Tomaz; M. Helena Garcia. "Ruthenium and iron metallodrugs: new inorganic and organometallic complexes as prospective anticancer agents". In Synthetic Inorganic Chemistry New Perspectives, edited by Ewan J. M. Hamilton. Elsevier, 2021.
    Published
  2. Andreia Valente; Tânia S. Morais; Maria Helena Garcia. "Ruténio - o elemento que não para de nos surpreender!". In Os Elementos em Ciências - Uma viagem pela Tabela Periódica (printed version & EPub), edited by Ana Mourato; Ana Paula Carvalho; Filomena Leitão; Teresa Pamplona. Lisbon, Portugal: Faculdade de Ciências da Universidade de Lisboa, 2020.
    Published
  3. Tânia S. Morais; Maria José Villa de Brito. Corresponding author: Tânia S. Morais. "O cobre "potagonista de todos os tempos"". In Os Elementos em Ciências - Uma viagem pela Tabela Periódica (printed version & EPub), edited by Ana Mourato; Ana Paula Carvalho; Filomena Leitão; Teresa Pamplona. Lisbon, Portugal: Faculdade de Ciências da Universidade de Lisboa, 2020.
    Published
  4. António Matos; Filipa Mendes; Andreia Valente; Tânia S. Morais; Ana Isabel Tomaz; Philippe Zinck; Maria Helena Garcia; Manuel Bicho; Fernanda Marques. "Ruthenium-Based Anticancer Compounds: Insights into Their Cellular Targeting and Mechanism of Action". In Ruthenium Complexes: Photochemical and Biomedical Applications, edited by Alvin A. Holder; Lothar Lilge; Wesley R. Browne; Mark A.W. Lawrence; Jimmie L. Bullock Jr., 201-219. Wiley-VCH Verlag GmbH & Co. KGaA, 2018.
    Published • 10.1002/9783527695225.ch10
  5. Tiago J. Silva; Paulo J. Mendes; Tânia S. Morais; Andreia Valente; M. Paula Robalo; M. Helena Garcia. ""RuCp" a versatile moiety: From NLO to antitumor properties". In Ruthenium: Synthesis, Physicochemical Properties and Applications, edited by Gary P. Keeler, 105-164. Nova Science Publishers, Inc., 2014.
    Published
  6. Tânia S. Morais; Maria Helena Garcia. "On the Track to Cancer Therapy: Paving New Ways with Ruthenium Organometallics". In Advances in Organometallic Chemistry and Catalysis: The Silver / Gold Jubilee International Conference on Organometallic Chemistry Celebratory Book, edited by Armando J. L. Pombeiro, 581-588. Wiley, 2013.
    Published • 10.1002/9781118742952.ch43
Conference paper
  1. Inês D.S. Pires; Tânia S. Morais; Miguel Machuqueiro. "New antitumor Ru-based compound derivatives optimized using in silico methods". Paper presented in 8º Encontro Jovens Investigadores de Biologia Computacional Estrutural (EJIBCE2021), 2021.
    Published • 10.3390/mol2net-07-12106
  2. João F. Machado; Miguel Machuqueiro; Fernanda Marques; M. Helena Garcia; João D.G. Correia; Tânia S. Morais. Corresponding author: Tânia S. Morais. "Targeting FGFR(+) breast cancer cells with half-sandwich ruthenium(II)-cyclopentadienyl peptide conjugates". Paper presented in 7th Portuguese Young Chemists Meeting, 2021.
    Published
  3. Fernanda Marques; Sílvia A. Sousa; Jorge H. Leitão; Tânia S. Morais; Yann Le Gal; Dominique Lorcy. "Gold(III) bisdithiolate complexes: molecular conductors that also exhibit antitumor and antimicrobial activities". Paper presented in 4th International Congress of CiiEM 2019 on Health, Well-Being and Ageing in the 21st Century, 2019.
    Published
  4. Maria Helena Garcia; Andreia Valente; Tânia S. Morais; Ana Isabel Tomaz. "Ruthenium new drug: paving the way for cancer therapy". Paper presented in 18th International Conference on Biological Inorganic Chemistry (ICBIC), Florianopolis, 2017.
    Published • doi.org/10.1007/s00775-017-1475-y
  5. Maria Helena Garcia; Andreia Valente; Tânia S. Morais; Fernanda Marques. "Ruthenium Organometallic compounds as promising antimetastatic drugs for breast cancer chemotherapy". Paper presented in European Chemistry Congress, Rome, 2016.
    Published • 10.4172/21503494.C1.002
  6. Maria Helena Garcia; Tânia S. Morais; Fernanda Marques; Andreia Valente. "Ruthenium drugs for cancer therapy: small structural changes, different in vivo performances". Paper presented in 4th International Conference on Medicinal Chemistry and Computer Aided Drug Designing, Atlanta, 2015.
    Published • 10.4172/21610444.C1.015
  7. Maria Helena Garcia; Tânia S. Morais; Andreia Valente; Fernanda Marques. "Tracking antitumor drugs: Ruthenium(II)cyclopentadienyl complexes as promising agents". Paper presented in 3rd International Conference on Medicinal Chemistry & Computer Aided Drug Designing, San Francisco, 2014.
    Published • 10.4172/21610444.S1.011
  8. Fernanda Marques; Leonor Côrte-Real; António P. Matos; Tânia S. Morais; Irina Alho; Ana Isabel Tomaz; Maria Helena Garcia; Manuel P. Bicho. "Intracellular distribution of antitumor Ru(II) compounds: the lysosome and the lysosomal enzymes as targets for anticancer metal based Drugs". Paper presented in XLVI Congress of the Portuguese Society for Microscopy 2012, Lisbon, 2012.
    Published • 10.1017/S1431927613000664
  9. Tânia S. Morais; Maria Helena Garcia; M. Paula Robalo; Andreia Valente; Virtudes Moreno; Mercè Font-Bardia; Teresa Calvet; Julia Lorenzo; Francesc X. Avilés. "Cytotoxicity Studies and DNA Interaction of New Ruthenium(II) Cyclopentadienyl Complexes with Nitrogen Coordinated Ligands". Paper presented in XII Iberian Meeting of Electrochemistry and XVI Meeting of the Portuguese Electrochemical Society, Lisbon, 2010.
    Published
Conference poster
  1. Tânia S. Morais; João Franco Machado; Marco Sá; Miguel Machuqueiro; Fernanda Marques; M. Helena Garcia; João D. G. Correia. Corresponding author: Tânia S. Morais. "Targeted delivery of Ru-cyclopentadienyl complexes to breast cancer cells with FGFR-specific peptides". Paper presented in 8th Latin American Symposium on Coordination and Organometallic Chemistry (Virtual), 2022.
  2. João Franco Machado; Sandra Cordeiro; Joana N. Duarte; M. Joana Lourenço; Pedro V. Baptista; M. Helena Garcia; Alexandra R. Fernandes; Tânia S. Morais. Corresponding author: Tânia S. Morais. "New cobalt-cyclopentadienyl complexes with promising in vitro antiproliferative activity". Paper presented in 8th Latin American Symposium on Coordination and Organometallic Chemistry (Virtual), 2022.
  3. Maria J. Villa de Brito; João F. Machado; Tânia S. Morais. Corresponding author: Tânia S. Morais. "Copper(I) complexes with anticancer activity". Paper presented in 8th Latin American Symposium on Coordination and Organometallic Chemistry (Virtual), 2022.
  4. Inês D.S. Pires; Tânia S. Morais; Miguel Machuqueiro. "New antitumor Ru-based compound derivatives optimized using in silico methods". Paper presented in 8º Encontro Jovens Investigadores de Biologia Computacional Estrutural (EJIBCE2021), Coimbra, Portugal, 2021.
  5. M. Paula Robalo; João Franco Machado; Paulo J. Mendes; Tânia S. Morais; M. Helena Garcia. Corresponding author: Tânia S. Morais. "Electrochemical behavior of 1,10-phenanthroline based [CpRu(PPh3)(L_L)]+ complexes". Paper presented in XXIV Meeting of the Portuguese Electrochemical Society, Tomar, Portugal, 2021.
  6. Tânia S. Morais; João Franco Machado; Miguel Machuqueiro; Fernanda Marques; M. Helena Garcia; João D. G. Correia. Corresponding author: Tânia S. Morais. "Targeting metastatic breast cancer with half-sandwich ruthenium(ii)-cyclopentadienyl peptide conjugates". Paper presented in 56th International Conference on Medicinal Chemistry, RICT 2021 (virtual)., 2021.
  7. João Franco Machado; Miguel Machuqueiro; Fernanda Marques; M. Helena Garcia; João D. G. Correia; Tânia S. Morais. Corresponding author: Tânia S. Morais. "New ruthenium-peptide conjugates for selective targeting of breast cancer". Paper presented in CQE Days 2021 - Spring Meeting (virtual)., 2021.
  8. João Franco Machado; Miguel Machuqueiro; Fernanda Marques; M. Helena Garcia; João D. G. Correia; Tânia S. Morais. Corresponding author: Tânia S. Morais. "Targeting FGFR(+) breast cancer cells with half-sandwich ruthenium(II)-cyclopentadienyl peptide conjugates". Paper presented in 7th Portuguese Young Chemist Meeting (virtual), Bragança, Portugal, 2021.
  9. João Franco Machado; Miguel Machuqueiro; Fernanda Marques; M. Paula Robalo; M. Fátima M. Piedade; M. Helena Garcia; João D. G. Correia; Tânia S. Morais. Corresponding author: Tânia S. Morais. "Ru-peptide conjugates for targeting metastatic breast cancer". Paper presented in 2nd CQE Days Spring Meeting (Virtual)., 2020.
  10. Andreia Valente; Tânia S. Morais; Leonor Côrte-Real; Ana Isabel Tomaz; M. José Brito; M. Helena Garcia. "Metallodrugs for cancer therapy: challenges and expectations". Paper presented in Ciências Research Day, Lisbon, Portugal, 2019.
  11. João Franco Machado; Margarida P. Pereira; M. Paula Robalo; M. Fátima M. Piedade; M. Helena Garcia; Tânia S. Morais. Corresponding author: Tânia S. Morais. "New ruthenium(II)-cyclopentadienyl complexes for cancer therapy: synthesis, characterisation and interaction with human serum albumin". Paper presented in 4Th Meeting of the College of Chemistry (4ECQUL) - Chemistry: Shaping The Future, Lisbon, Portugal, 2019.
  12. Fernanda Marques; Sílvia A. Sousa; Jorge H. Leitão; Tânia S. Morais; Yann Le Gal; Dominique Lorcy. "Gold(III) dithiolate complexes: molecular conductors that also exhibit antitumor and antimicrobial activities". Paper presented in 4th International Congress of CiiEM 2019 on Health, Well-Being and Ageing in the 21st Century, Caparica, Portugal., 2019.
  13. Margarida P. Pereira; João Franco Machado; M. Fátima M. Piedade; M. Helena Garcia; Tânia S. Morais. Corresponding author: Tânia S. Morais. "Synthesis and characterization of a new family of ruthenium(II) complexes with phenantroline derivated ligands for anticancer applications". Paper presented in 1st CQE Days - Spring Meeting 2019, Lisbon, Portugal, 2019.
  14. João Franco Machado; Fernanda Marques; M. Fátima M. Piedade; Maria J. Villa de Brito; M. Helena Garcia; Tânia S. Morais. Corresponding author: Tânia S. Morais. "New selective Copper(I) complexes for prostate cancer cells". Paper presented in 1st CQE Days - Spring Meeting 2019, Lisbon, Portugal, 2019.
  15. Tânia S. Morais; Catarina Bravo; João Franco Machado; Nuno Xavier; M. José Villa de Brito; M. Helena Garcia. Corresponding author: Tânia S. Morais. "Synthesis and characterization of new copper(I) complexes comprising carbohydrates for cancer therapy". Paper presented in 29th International Carbohydrate Symposium (ICS2018), Lisbon, Portugal, 2018.
  16. João Franco Machado; Inês D. Ribeiro; Maria José Villa de Brito; M. Fátima M. Piedade; Maria Helena Garcia; Tânia S. Morais. Corresponding author: Tânia S. Morais. "Synthesis and structural characterisation of a new family of copper(I)-phosphane complexes for cancer therapy". Paper presented in 3rd Meeting of the College of Chemistry (3ECQUL), Lisbon, Portugal, 2018.
  17. Catarina Bravo; M. Paula Robalo; Fernanda Marques; M. Fátima Minas da Piedade; Maria Helena Garcia; Maria José Villa de Brito; Tânia S. Morais. Corresponding author: Tânia S. Morais. "Heterobimetallic Cu(I)-Fe(II) complexes with NN-, NO-, NS- heteroaromatic ligands for cancer therapy: a combined structural, electrochemical and biological study". Paper presented in 3rd Meeting of the College of Chemistry (3ECQUL), Lisbon, Portugal, 2018.
  18. Maria Helena Garcia; Andreia Valente; Tânia S. Morais; Ana Isabel Tomaz. "Ruthenium new drug: paving the way for cancer therapy". Paper presented in ICBIC18- 18th International Conference on Biological Inorganic Chemistry, Florianopólis, Brazil, 2017.
  19. Filipa D. de Oliveira; João Freire; M. Paula Robalo; M. Fátima M. Piedade; David Andreu; Ana Salomé Veiga; M. Helena Garcia; et al. Corresponding author: Tânia S. Morais. "Study of cell penetrating peptides as drug delivery systems for chemotherapeutic drugs and their anticancer properties". Paper presented in A Química na Investigação da ULisboa - 1º Encontro do Colégio de Química (1ECQUL), Lisbon, Portugal, 2017.
  20. Miguel Freitas; Tânia S. Morais; Nuno Xavier; M. Helena Garcia. Corresponding author: Tânia S. Morais. "New Ruthenium(II) Complexes Comprising Carbohydrates for cancer therapy: Synthesis and characterization". Paper presented in ChemBioChem, Lisbon, Portugal, 2017.
  21. António P. Matos; Lurdes Gano; Francisco Tortosa; Teresa Pinheiro; Tânia S. Morais; Andreia Valente; Ana Isabel Tomaz; Maria Helena Garcia; Fernanda Marques. "Microscopic Analysis of the Antitumor Effects of Ruthenium Complexes in a Prostate Cancer Model". Paper presented in Congresso Internacional From Basic Sciences to Clinical Research (First International Congress of CiiEM), Almada, Portugal., 2015.
  22. Ana Cristina Poeta; A. Sofia Assis; Andreia Valente; Tânia S. Morais; Fernanda Marques; M. Paula Robalo; Susana Santos; Ana Isabel Tomaz; M. Helena Garcia. "On the field of metallodrugs: novel ruthenium(II) complexes with thiosemicarbazones". Paper presented in 19th European Symposium on Organic Chemistry (ESOC2015), Lisbon, Portugal, 2015.
  23. Miguel de Freitas; Tânia S. Morais; Nuno M. Xavier; Maria Helena Garcia. Corresponding author: Tânia S. Morais. "Synthesis of new ruthenium cyclopentadienyl complexes comprising carbohydrate ligands as potential antitumor agents". Paper presented in 19th European Symposium on Organic Chemistry (ESOC2015), Lisbon, Portugal, 2015.
  24. Fernanda Marques; Leonor Côrte-Real; Tânia S. Morais; Maria Helena Garcia; António Matos; Manuel Bicho. "Ruthenium based anticancer compounds: Insights into their uptake mechanisms and cellular targets". Paper presented in 4th World Congress on Cancer Science & Therapy, Chicago, USA, 2014.
  25. Tânia S. Morais; Fernanda Marques; M. Paula Robalo; Paulo J. A. Madeira; António Matos; M. Helena Garcia. "New water soluble ruthenium(II)cyclopentadienyl compound as potencial anticancer agent". Paper presented in EFMC International Symposium on Medicinal Chemistry, Lisbon, Portugal, 2014.
  26. Esteban Rodriguez Arce; Cynthia Sarniguet; Tânia S. Morais; Isabel Tomaz; Andrea Medeiros; Marcelo Comini; Javier Varela; et al. "Actividad en Líneas de Células Tumorales y Parásitos Trypanosomátidos de un Compuesto Organometálico Rutenio Clotrimazol". Paper presented in XV Jornadas de la Sociedad Uruguaya de Biociencias, Maldonado, Uruguai, 2014.
  27. Fernanda Marques; António P. Matos; Leonor Côrte-Real; Tânia S. Morais; M. Helena Garcia. "Novel Pathways for Anticancer Therapy:the Role of Golgi network in the mechanism of cell death of organometallic Ru complexes". Paper presented in Microscopy in Research, Almada, Portugal, 2013.
  28. M. Helena Garcia; Tânia S. Morais; Ana Isabel Tomaz; Andreia Valente; Fernanda Marques. "Cyclopentadienyl ruthenium(macro)metallodrugs: large spectrum antitumor agentes". Paper presented in Drug Discovery & Therapy World Congress, Boston, EUA, 2013.
  29. Cynthia Sarniguet; Tânia S. Morais; Ana Isabel Tomaz; Andrea Medeiros; Marcelo Comini; Lucía Otero; M. Helena Garcia; Dinorah Gambino. "New ruthenium(II) cyclopentadienyl thiosemicarbazone complexes with antitrypanosomal activity". Paper presented in 12th International Symposium on Metal Ions and Medicine, Punta del Este, Uruguay, 2013.
  30. Andreia Valente; M. Helena Garcia; Tânia S. Morais; Fernanda Marques; Yong Miao; Philippe Zinck. "New targeted bifunctional polymeric metal complexes for drug delivery in cancer therapy". Paper presented in 3rd National Meeting on Medicinal Chemistry, Aveiro, Portugal, 2012.
  31. Tânia S. Morais; M. Helena Garcia; Ana Isabel Tomaz; Fernanda Marques; Filipa Mendes. "New antitumor ruthenium(II) organometallic complexes: cytotoxicity and protein interaction". Paper presented in XXV International Conference on Organometallic Chemistry (ICOMC 2012), Lisbon, Portugal, 2012.
  32. Tânia S. Morais; M. Helena Garcia; Ana I. Tomaz; Fernanda Marques; Filipa Mendes. "New anti-tumour ruthenium(II) organometallic complexes: cytotoxicity and protein interaction". Paper presented in International Symposium on Metal Complexes, ISMEC 2012, Lisbon, Portugal, 2012.
  33. Tânia S. Morais; M. Helena Garcia; Ana Isabel Tomaz; Fernanda Marques; M. Paula Robalo; Paulo J. Amorim Madeira. "New ruthenium(II) cyclopentadienyl compounds: cytotoxicity and proteins binding". Paper presented in 11 International Symposium and Applied Bioinorganic Chemistry, Barcelona, Spain, 2011.
  34. M. Helena Garcia; Tânia S. Morais; M. Paula Robalo; M. José Villa de Brito. "New piano-stool ruthenium(II) complexes bearing 1-butylimidazole heteroaromatic ligand". Paper presented in XIX EuCheMS Conference on Organometallic Chemistry, Toulouse, France, 2011.
  35. Tânia S. Morais; M. Helena Garcia; Paulo J. Amorim Madeira; M. Helena Florêncio; Virtudes Moreno. "Interaction of new ruthenium(II) cyclopentadienyl compounds with proteins". Paper presented in XXII National Meeting SPQ, Braga, Portugal, 2011.
  36. Paulo J. Amorim Madeira; Tânia S. Morais; M. Helena Garcia; M. Helena Florêncio. "Gas-phase behaviour of ruthenium(II) cyclopentadienyl derivatives: an FT-ICR mass spectrometry study". Paper presented in XXII National Meeting SPQ, Braga, Portugal, 2011.
  37. Tânia S. Morais; M. Helena Garcia; Ana Isabel Tomaz; Paulo J.A. Madeira; M. Helena Florêncio; Fernanda Marujo Marques. "Novos compostos de "Ru(II)(eta5-C5H5)" como potenciais agentes anti-tumorais". Paper presented in Ciência QB-1º Encontro dos Alunos de Doutoramento do DQB - FCUL, Lisbon, Portugal, 2011.
  38. Tânia S. Morais; M. Helena Garcia; M. Paula Robalo; Andreia Valente; Virtudes Moreno; Mercè Font-Bardia; Teresa Calvet; Julia Lorenzo; Francesc X. Avilés. "Cytotoxicity studies and DNA interaction of new ruthenium(II) cyclopentadienyl complexes with nitrogen coordinated ligands". Paper presented in XII Iberic Meeting of electrochemistry & XVI Meetinf of the Portuguese Electrochemical Society (XII IME), Lisbon, Portugal, 2010.
  39. Susana Quintal; Tânia S. Morais; Paula Robalo; Fátima Piedade; Maria José Villa de Brito; Maria Helena Garcia; João Madureira; et al. "Design of Ferrocenyl Compounds with Leishmanicidal Activity". Paper presented in XV Brazilian Meeting on Inorganic Chemistry (XV BMIC), Angra dos Reis, Brasil, 2010.
  40. Ana Isabel Tomaz; Tamás Jakusch; Tânia S. Morais; Rodrigo F. M. de Almeida; Fernanda Marques; Éva A. Enyedy; João Costa Pessoa; Tamás Kiss; M. Helena Garcia. "Interaction of cytotoxic ruthenium(II) cyclopentadienyl complexes with serum albumin". Paper presented in 10th European Biological Inorganic Chemistry Conference (EUROBIC 2010), Thessalonica, Greece, 2010.
  41. Tânia S. Morais; M. Helena Garcia; Pedro Florindo; João Ribeiro; M. Paula Robalo; Virtudes Moreno; Julia Lorenzo; Francesc X. Avilés. "Studies of the antiproliferative activity of ruthenium(II) cyclopentadienyl derived complexes with nitrogen coordinated ligands". Paper presented in 8th Inorganic Chemistry Conference, Curia, Portugal, 2009.
  42. Maria J. Villa de Brito; Tânia S. Morais; João Madureira; Susana Quintal; M. Helena Garcia. "Synthesis and characterization of new ferrocenylamide compounds with appended N-heterocycles designed for Leishmanicidal activity". Paper presented in 8th Inorganic Chemistry Conference, Curia, Portugal, 2009.
  43. M. Fátima M. Piedade; M. Helena Garcia; Andreia Valente; Pedro Florindo; Tânia S. Morais; M. Teresa Duarte. "Molecular and crystal structures of new ruthenium(II) mixed metallocene derived complexes". Paper presented in 8th Inorganic Chemistry Conference, Curia, Portugal, 2009.
  44. Ana Isabel Tomaz; Tamás Jakusch; Tânia S. Morais; M. Helena Garcia; Éva A. Enyedy; João Costa Pessoa; Tamás Kiss. "Human Albumin Binding to Cytotoxic Ruthenium(II) Cyclopentadienyl-type Complexes". Paper presented in 10th International Symposium on Applied Bioinorganic Chemistry (ISABC 10), Debrecen, Hungry, 2009.
  45. M. Helena Garcia; Tânia S. Morais; Andreia Valente; M. Paula Robalo; Virtudes Moreno; Julia Lorenzo; Francesc X. Avilés. "DNA interaction and cytotoxicity studies of new ruthenium(II) cyclopentadienyl derivative complexes containing heteroaromatic ligands". Paper presented in XVIII EuCheMS International conference on Organometallic Chemistry, Goteborg, Sweden, 2009.
  46. M. Helena Garcia; Andreia Valente; Tânia S. Morais; Pedro Florindo; M. Fátima M. Piedade; Virtudes Moreno. "Studies on DNA interaction of new mixed metallocene ruthenium(II) derived complexes". Paper presented in International Conference on Organometallic Chemistry, Rennes, France, 2008.
Edited book
  1. 29th International Carbohydrate Symposium, Book of Abstracts. Lisbon, Portugal: on line. 2018.
    Published • Editor
Encyclopedia entry
  1. João Franco Machado; João D. G. Correia; Tânia S. Morais*. Corresponding author: Tânia S. Morais*. "Cell Adhesion Molecules (CAM). Encyclopedia. In: https://encyclopedia.pub/11529/". In Encyclopedia. In: https://encyclopedia.pub/11529/, 2021.
    Published
Journal article
  1. João Franco Machado; Tânia S. Morais* . Corresponding author: Tânia S. Morais*. "Are smart delivery systems the solution to overcome the lack of selectivity of current metallodrugs in cancer therapy? | Perspective review (by invitation)". Dalton Transactions 51 7 (2022): 2593-2609. http://dx.doi.org/10.1039/d1dt04079k.
    Published • 10.1039/d1dt04079k
  2. Rúben D. M. Silva; João Franco Machado; Kyle Gonçalves; Francisco M. Lucas ; Salete Batista ; Rita Melo; Tânia S. Morais*; João D. G. Correia*. Corresponding author: Tânia S. Morais*. "Ultrasonication Improves Solid Phase Synthesis of Peptides Specific for Fibroblast Growth Factor Receptor and for the Protein-Protein Interface RANK-TRAF6". Molecules 26 23 (2021): 7349. http://dx.doi.org/10.3390/molecules26237349.
    Open access • Published • 10.3390/molecules26237349
  3. Jonas F. Schlagintweit; Christian H. G. Jakob ; Nicola L. Wilke; Marie Ahrweiler; Corazon Frias ; Jerico Frias ; Marcel König; et al. "Gold(I) Bis(1,2,3-triazol-5-ylidene) Complexes as Promising Selective Anticancer Compounds". Journal of Medicinal Chemistry 64 21 (2021): 15747-15757. http://dx.doi.org/10.1021/acs.jmedchem.1c01021.
    Published • 10.1021/acs.jmedchem.1c01021
  4. Filipa C. Santos; Paulo J. Costa; M. Helena Garcia; Tânia S. Morais*. Corresponding author: Tânia S. Morais*. "Binding of RuCp complexes with human apo-transferrin: fluorescence spectroscopy and molecular docking methods". BioMetals 34 5 (2021): 1029-1042. http://dx.doi.org/10.1007/s10534-021-00325-w.
    Published • 10.1007/s10534-021-00325-w
  5. João Franco Machado; João D. G. Correia*; Tânia S. Morais*. Corresponding author: Tânia S. Morais*. "Emerging Molecular Receptors for the Specific-Target Delivery of Ruthenium and Gold Complexes into Cancer Cells". Molecules 26 11 (2021): 3153. http://dx.doi.org/10.3390/molecules26113153.
    Open access • Published • 10.3390/molecules26113153
  6. Ben Woods; Rúben D. M. Silva; Claudia Schmidt; Darren Wragg ; Marco Cavaco; Vera Neves ; Vera F. C. Ferreira ; et al. Corresponding author: Angela Casini. "Bioconjugate Supramolecular Pd2+ Metallacages Penetrate the Blood Brain Barrier In Vitro and In Vivo". Bioconjugate Chemistry 32 7 (2021): 1399-1408. http://dx.doi.org/10.1021/acs.bioconjchem.0c00659.
    Published • 10.1021/acs.bioconjchem.0c00659
  7. Diogo Sequeira; Pedro V. Baptista; Ruben Valente; M. Fátima M. Piedade; M. Helena Garcia; Tânia S. Morais*; Alexandra R. Fernandes* . Corresponding author: Tânia S. Morais*. "Cu(i) complexes as new antiproliferative agents against sensitive and doxorubicin resistant colorectal cancer cells: synthesis, characterization, and mechanisms of action". Dalton Transactions 50 5 (2021): 1845-1865. http://dx.doi.org/10.1039/d0dt03566a.
    Published • 10.1039/d0dt03566a
  8. João Franco Machado; Diogo Sequeira; Fernanda M. Marques; Maria Fátima Minas da Piedade; Maria José Villa de Brito; M. Helena Garcia; Alexandra R. Fernandes; Tânia S. Morais*. Corresponding author: Tânia S. Morais*. "New copper(I) complexes selective for prostate cancer cells | Selected as HOT TOPIC". Dalton Transactions 49 (2020): 12273-12286. https://pubs.rsc.org/en/content/articlelanding/2020/dt/d0dt02157a/unauth#!divAbstract.
    Published • 10.1039/D0DT02157A
  9. João Franco Machado; Miguel Machuqueiro; Fernanda M. Marques; M. Paula A. Robalo ; M. Fátima M. Piedade; M. Helena Garcia; João D. G. Correia*; Tânia S. Morais*. Corresponding author: Tânia S. Morais*. "Novel "ruthenium cyclopentadienyl"-peptide conjugate complexes against human FGFR(+) breast cancer". Dalton Transactions 49 (2020): 5974-5987. http://dx.doi.org/10.1039/d0dt00955e.
    Published • 10.1039/d0dt00955e
  10. Diana Fontinha; Sílvia A. Sousa; Tânia S. Morais; Miguel Prudêncio; Jorge H. Leitão; Yann Le Gal; Dominique Lorcy; et al. "Gold(III) bis(dithiolene) complexes: from molecular conductors to prospective antitumor, antimicrobial and antiplasmodial agentes". Metallomics 12 (2020): 974-987. https://pubs.rsc.org/en/content/articlelanding/2020/mt/d0mt00064g.
    Published • 10.1039/D0MT00064G
  11. Lurdes Gano; Teresa Pinheiro; António P. Matos; Francisco Tortosa; Tiago F. Jorge ; Maria S. Gonçalves ; Marta Martins ; et al. "Antitumour and Toxicity Evaluation of a Ru(II)-Cyclopentadienyl Complex in a Prostate Cancer Model by Imaging Tools". Anti-Cancer Agents in Medicinal Chemistry 19 10 (2019): 1262-1275. http://dx.doi.org/10.2174/1871520619666190318152726.
    Published • 10.2174/1871520619666190318152726
  12. Catarina Bravo; M. Paula Robalo; Fernanda Marques; Alexandra R. Fernandes; Diogo A. Sequeira; M. Fátima M. Piedade; M. Helena Garcia; Maria J. Villa de Brito; Tânia S. Morais*. Corresponding author: Tânia S. Morais*. "First heterobimetallic Cu(i)-dppf complexes designed for anticancer applications: synthesis, structural characterization and cytotoxicity". New Journal of Chemistry 43 31 (2019): 12308-12317. http://dx.doi.org/10.1039/c9nj02068c.
    Published • 10.1039/c9nj02068c
  13. Tânia S. Morais*; Yann Jousseaume; M. Fátima M. Piedade; Catarina Roma-Rodrigues; Alexandra R. Fernandes; Fernanda Marques; Maria J. Villa de Brito; M. Helena Garcia. Corresponding author: Tânia S. Morais*. "Important cytotoxic and cytostatic effects of new copper(i)-phosphane compounds with N,N, N,O and N,S bidentate ligands". Dalton Transactions 47 23 (2018): 7819-7829. https://doi.org/10.1039/C8DT01653D.
    Published • 10.1039/C8DT01653D
  14. João Lopes ; David Alves; Tânia S. Morais*; Paulo J. Costa; M. Fátima M. Piedade; Fernanda Marques; Maria J. Villa de Brito; M. Helena Garcia. Corresponding author: Tânia S. Morais*. "New copper(I) and heteronuclear copper(I)-ruthenium(II) complexes: Synthesis, structural characterization and cytotoxicity". Journal of Inorganic Biochemistry 169 (2017): 68-78. http://dx.doi.org/10.1016/j.jinorgbio.2017.01.007.
    Published • 10.1016/j.jinorgbio.2017.01.007
  15. Nuno Mendes; Francisco Tortosa; Andreia Valente; Fernanda Marques; António Matos; Tânia S. Morais; Ana Tomaz; Fátima Gärtner; Maria Garcia. "In vivo Performance of a Ruthenium-cyclopentadienyl Compound in an Orthotopic Triple Negative Breast Cancer Model". Anti-Cancer Agents in Medicinal Chemistry 16 999 (2016): 1-1. http://dx.doi.org/10.2174/1871520616666160922165133.
    Published • 10.2174/1871520616666160922165133
  16. Tânia S. Morais; Andreia Valente; A.Isabel Tomaz; Fernanda Marques; M.Helena Garci. "Tracking antitumor metallodrugs: Promising agents with the Ru(II)- and Fe(II)-cyclopentadienyl scaffolds | Selected as Issue Special Report". Future Medicinal Chemistry 8 5 (2016): 527-544. https://www.future-science.com/doi/10.4155/fmc.16.7?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed&.
    Published • 10.4155/fmc.16.7
  17. Mariana Fernández; Esteban Rodríguez Arce; Cynthia Sarniguet; Tânia S. Morais; Ana Isabel Tomaz; Claudio Olea Azar; Roberto Figueroa; et al. "Novel ruthenium(II) cyclopentadienyl thiosemicarbazone compounds with antiproliferative activity on pathogenic trypanosomatid parasites". Journal of Inorganic Biochemistry 153 (2015): 306-314. http://www.scopus.com/inward/record.url?eid=2-s2.0-84982686493&partnerID=MN8TOARS.
    Published • 10.1016/j.jinorgbio.2015.06.018
  18. Esteban Rodríguez Arce; Cynthia Sarniguet; Tânia S. Morais; Marisol Vieites; A. Isabel Tomaz; Andrea Medeiros; Marcelo Comini; et al. "A new ruthenium cyclopentadienyl azole compound with activity on tumor cell lines and trypanosomatid parasites". Journal of Coordination Chemistry 68 16 (2015): 2923-2937. http://www.scopus.com/inward/record.url?eid=2-s2.0-84982070308&partnerID=MN8TOARS.
    Published • 10.1080/00958972.2015.1062480
  19. Leonor Côrte-Real; Filipa Mendes; Joana Coimbra; Tânia S. Morais; Ana Isabel Tomaz; Andreia Valente; Maria Helena Garcia; et al. "Anticancer activity of structurally related ruthenium(II) cyclopentadienyl complexes". Journal of Biological Inorganic Chemistry 19 6 (2014): 853-867. http://www.scopus.com/inward/record.url?eid=2-s2.0-84905864221&partnerID=MN8TOARS.
    Published • 10.1007/s00775-014-1120-y
  20. Tânia S. Morais; Filipa C. Santos; Tiago F. Jorge; Leonor Côrte-Real; Paulo J. A. Madeira; Fernanda Marques; M. Paula Robalo; et al. "New water-soluble ruthenium(II) cytotoxic complex: Biological activity and cellular distribution". Journal of Inorganic Biochemistry 130 1 (2014): 1-14. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885498325&partnerID=MN8TOARS.
    Published • 10.1016/j.jinorgbio.2013.09.013
  21. Ana Cristina Gonçalves; Tânia S. Morais; M. Paula Robalo; Fernanda Marques; Fernando Avecilla; Cristina P. Matos; Isabel Santos; Ana Isabel Tomaz; M. Helena Garcia. "Important cytotoxicity of novel iron(II) cyclopentadienyl complexes with imidazole based ligands". Journal of Inorganic Biochemistry 129 (2013): 1-8. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882795489&partnerID=MN8TOARS.
    Published • 10.1016/j.jinorgbio.2013.07.033
  22. Susana Quintal; Tânia S. Morais; Cristina P. Matos; M. Paula Robalo; M. Fátima M. Piedade; Maria J. Villa de Brito; M. Helena Garcia; et al. "Synthesis, structural characterization and leishmanicidal activity evaluation of ferrocenyl N-heterocyclic compounds". Journal of Organometallic Chemistry 745-746 (2013): 299-311. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883307751&partnerID=MN8TOARS.
    Published • 10.1016/j.jorganchem.2013.07.044
  23. Leonor Côrte-Real; António P. Matos; Irina Alho; Tânia S. Morais; Ana Isabel Tomaz; Maria Helena Garcia; Isabel Santos; Manuel P. Bicho; Fernanda Marques. "Cellular uptake mechanisms of an antitumor ruthenium compound: The endosomal/lysosomal system as a target for anticancer metal-based drugs". Microscopy and Microanalysis 19 5 (2013): 1122-1130. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884579362&partnerID=MN8TOARS.
    Published • 10.1017/S143192761300175X
  24. Tânia S. Morais; Filipa C. Santos; Leonor Côrte-Real; M. Helena Garcia. "Exploring the effect of the ligand design on the interactions between [Ru(¿5-C5H5)(PPh3)(N,O)][CF 3SO3] complexes and human serum albumin". Journal of Inorganic Biochemistry 129 (2013): 94-101. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884952269&partnerID=MN8TOARS.
    Published • 10.1016/j.jinorgbio.2013.09.008
  25. Tânia S. Morais; Filipa C. Santos; Leonor Côrte-Real; Fernanda Marques; M. Paula Robalo; Paulo J. Amorim Madeira; M. Helena Garcia. "Biological activity and cellular uptake of [Ru(¿5-C 5H5)(PPh3)(Me2bpy)][CF 3SO3] complex". Journal of Inorganic Biochemistry 122 (2013): 8-17. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873704110&partnerID=MN8TOARS.
    Published • 10.1016/j.jinorgbio.2013.01.011
  26. Ana Isabel Tomaz; Tamás Jakush; Tânia S. Morais; Fernanda Marques; Rodrigo F. M. de Almeida; Filipa Mendes; Éva A. Enyedy; et al. "[RuII(¿5-C5H5 (bipy)(PPh3)]+, a promising large spectrum antitumor agent: Cytotoxic activity and interaction with human serum albumin". Journal of Inorganic Biochemistry 117 (2012): 261-269. http://www.scopus.com/inward/record.url?eid=2-s2.0-84869080345&partnerID=MN8TOARS.
    Published • 10.1016/j.jinorgbio.2012.06.016
  27. Paulo J. Amorim Madeira§; Tânia S. Morais§; Tiago Silva; Pedro Florindo; M. Helena Garcia; § These authors contributed equally to this work. "Gas-phase behaviour of Ru(II) cyclopentadienyl-derived complexes with N-coordinated ligands by electrospray ionization mass spectrometry: Fragmentation pathways and energetics". Rapid Communications in Mass Spectrometry 26 15 (2012): 1675-1686. https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/rcm.6276.
    Published • 10.1002/rcm.6276
  28. Tânia S. Morais; M. Helena Garcia; M. Paula Robalo; M. Fátima M. Piedade; M. Teresa Duarte; M. José Villa de Brito; Paulo J. Amorim Madeira. "Synthesis and structural characterization of new piano-stool ruthenium(II) complexes bearing 1-butylimidazole heteroaromatic ligand". Journal of Organometallic Chemistry 713 (2012): 112-122. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862600442&partnerID=MN8TOARS.
    Published • 10.1016/j.jorganchem.2012.04.024
  29. Tânia S. Morais; Tiago J. L. Silva; Fernanda Marques; M. Paula Robalo; Fernando Avecilla; Paulo J. Amorim Madeira; Paulo J. G. Mendes; Isabel Santos; M. Helena Garcia. "Synthesis of organometallic ruthenium(II) complexes with strong activity against several human cancer cell lines". Journal of Inorganic Biochemistry 114 (2012): 65-74. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861986235&partnerID=MN8TOARS.
    Published • 10.1016/j.jinorgbio.2012.04.014
  30. Virtudes Moreno; Mercè Font-Bardia; Teresa Calvet; Julia Lorenzo; Francesc X. Avilés; M. Helena Garcia; Tânia S. Morais; Andreia Valente; M. Paula Robalo. "DNA interaction and cytotoxicity studies of new ruthenium(II) cyclopentadienyl derivative complexes containing heteroaromatic ligands". Journal of Inorganic Biochemistry 105 2 (2011): 241-249. http://www.scopus.com/inward/record.url?eid=2-s2.0-78649615202&partnerID=MN8TOARS.
    Published • 10.1016/j.jinorgbio.2010.10.009
  31. M. Helena Garcia; Andreia Valente; Pedro Florindo; Tânia S. Morais; M. Fátima M. Piedade; M. Teresa Duarte; Virtudes Moreno; Francesc X. Avilés; Julia Lorenzo. "New ruthenium(II) mixed metallocene derived complexes: Synthesis, characterization by X-ray diffraction and evaluation on DNA interaction by atomic force microscopy". Inorganica Chimica Acta 363 14 (2010): 3765-3775. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957982339&partnerID=MN8TOARS.
    Published • 10.1016/j.ica.2010.05.034
  32. Virtudes Moreno; Julia Lorenzo; Francesc X. Avilés; M. Helena Garcia; João Ribeiro; Tânia S. Morais; Pedro Florindo; M. Paula Robalo. "Studies of the antiproliferative activity of ruthenium (II) Cyclopentadienyl-derived complexes with nitrogen coordinated ligands". Bioinorganic Chemistry and Applications 2010 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-77954567506&partnerID=MN8TOARS.
    Published • 10.1155/2010/936834
  33. M. Helena Garcia; Tânia S. Morais; Pedro Florindo; M. Fátima M. Piedade; Virtudes Moreno; Carlos Ciudad; Veronica Noe. "Inhibition of cancer cell growth by ruthenium(II) cyclopentadienyl derivative complexes with heteroaromatic ligands". Journal of Inorganic Biochemistry 103 3 (2009): 354-361. http://www.scopus.com/inward/record.url?eid=2-s2.0-59649090635&partnerID=MN8TOARS.
    Published • 10.1016/j.jinorgbio.2008.11.016
Newsletter article
  1. Tânia S. Morais. Corresponding author: Tânia S. Morais. "Novos Compostos, Grandes Desafios", Química, Boletim da Sociedade Portuguesa de Química, 2014, https://www.spq.pt/magazines/BSPQuimica/665/article/30001893/pdf.
Online resource
  1. Paper selected by the Global Medical Discovery (online continuous dissemination): 2014 -Anticancer activity of structurally related ruthenium(II) cyclopentadienyl complexes", Leonor Côrte-Real, Filipa Mendes, Joana Coimbra, Tânia S. Morais, Ana Isabel Tomaz, Andreia Valente, M. Helena Garcia, Isabel Santos, Manuel Bicho, featured at Global Medical Discovery [ISSN 1929-8536]. 2014. https://globalmedicaldiscovery.com/?s=Anticancer+activity+of+structurally+related+ruthenium%28II%29+cyclopentadienyl+complexes.
  2. Paper selected by the Global Medical Discovery (online continuous dissemination): 2012 -[RuII( eta5-C5H5)(bipy)(PPh3)]+, a promising large spectrum antitumor agent: cytotoxic activity and interaction with Human Serum Albumin-, Ana Isabel Tomaz, Tamás Jakusch, Tânia S. Morais, Rodrigo F. M. de Almeida, Fernanda Marques, Filipa Mendes, Eva A. Enyedy, João Costa Pessoa, Támas Kiss, M. Helena Garcia. 2012. http://globalmedicaldiscovery.com/key-scientific-articles/ruii%CE%B7%E2%81%B5-c%E2%82%85h%E2%82%85bipypph%E2%82%83%E2%81%BA-a-promising-large-spectrum-antitumor-agent-cytotoxic-activity-and-interaction-with-human-serum-albumin/.
Thesis / Dissertation
  1. Tânia S. Morais. "Síntese de novos complexos bioorganometálicos de ruténio e avaliação das suas propriedades anti-tumorais". PhD, Universidade de Lisboa Faculdade de Ciências, 2013. https://repositorio.ul.pt/handle/10451/9908.
  2. Tânia S. Morais. "Síntese e caracterização de complexos organometálicos citotóxicos derivados do fragmento “CpRu” e avaliação das suas potencialidades como agentes antitumorais". Master, Universidade de Lisboa Faculdade de Ciências, 2008. https://repositorio.ul.pt/handle/10451/1272.
  3. Tânia S. Morais. "Síntese e caracterização de complexos de Ru(II) e Fe(II) com ligandos azotados. Estudo preliminar sobre as suas potencialidades como agentes antitumorais". Degree, Universidade de Lisboa Faculdade de Ciências, 2007.

Intellectual property

Patent
  1. Maria Helena Garcia; Andreia Valente; Tânia S. Morais; Ana Isabel Tomaz. 2016. "Macromolecular transition metal complexes for treatment of cancer and process for their preparation |WO 2016/087932,PT108082B, EA038640B1, EP3227307B1, CN107466297B, JP6726678B2, US15/533,289, under examination on Canada, Brazil and India)".
    Granted/Issued
  2. Maria Helena Garcia; Andreia Valente; Tânia S. Morais; Ana Isabel Tomaz. 2014. "Novos complexos macromoleculares de metais de transição para tratamento do cancro | PT Nº108.082". Portugal.
    Granted/Issued
  3. Maria Helena Garcia; Tânia S. Morais; Ana Isabel Tomaz; Fernanda Marques. 2013. "Water-soluble organometallic ruthenium and iron compounds presenting heteroaromatic ligands | PCT/IB2013/052035, WO 2013136296 A3".
    Expired
  4. Maria Helena Garcia; Tânia S. Morais; Ana Isabel Tomaz; Fernanda Marques; Filipa Mendes. 2012. "Transition metal complexes for pharmaceutical applications | PCT/IB2012/054914, WO 2013038395 A1". Portugal.
    Expired

Other

Other output
  1. Front Cover Dalton Transations journal ( volume 51, pages 2579-2580, February 2022). Front cover artwork highlighting the paper "Are smart delivery systems the solution to overcome the lack of selectivity of current metallodrugs in cancer therapy?". 2022. João Franco Machado; Tânia S. Morais*. https://pubs.rsc.org/en/content/articlelanding/2022/dt/d2dt90026b.
    10.1039/D2DT90026B
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2021/07/08 |Invited Seminar| Target-specific delivery of cytotoxic ruthenium complexes to breast cancer cells with peptides_ João Franco Machado, Miguel Machuqueiro, Fernanda Marques, M. Helena Garcia, João D. G. Correia, Tânia S. Morais* Radiopharmaceutical Sciences and Health Physics Workshop_ João Franco Machado, Miguel Machuqueiro, Fernanda Marques, M. Helena Garcia, João D. G. Correia, Tânia s. Morais*
Instituto Superior Técnico (Lisbon, Portugal)
2021/05/27 New ruthenium-peptide conjugates for selective targeting of breast cancer_ João Franco Machado, Miguel Machuqueiro, Fernanda Marques, M. Helena Garcia, João D. G. Correia, Tânia S. Morais* CQE Days 2021 - Spring Meeting (virtual)
Universidade de Lisboa Centro de Química Estrutural (Lisbon, Portugal)
2021/04/28 "Ruthenium metallodrugs for cancer therapy"_ Tânia S. Morais | lecture on Inorganic Chemistry from the 1st academic year of Sciences and Health Course, Faculdade de Ciências da Universidade de Lisboa, 2021 Lecture on Inorganic Chemistry from the 1st academic year of Sciences and Health Course, Faculdade de Ciências da Universidade de Lisboa
Faculdade de Ciências da Universidade de Lisboa (Lisbon, Portugal)
2021/04/16 |Invited seminar| Fighting metastatic breast cancer with ruthenium-peptide conjugates_Tânia S. Morais Palestra de Investigação NEQ/FCUL
Palestra de Investigação NEQ/FCUL (Lisbon, Portugal)
2020/04/21 |Invited| Ruthenium Chemistry for cancer therapy: ten years challenge _Tânia S. Morais Ciclo de Seminários da Universidade de Évora
(Évora, Portugal)
2020/02/06 Ruthenium-peptide conjugates for the selective treatment of triple-negative breast cancer_João D. G. Correia, João Franco Machado, Fernanda Marques, M. Helena Garcia, Tânia S. Morais* 17th Iberian Peptide Meeting (EPI 2020)
(Madrid, Spain)
2019/11/22 Copper(I)-phosphane complexes as potencial anticancer agents_João Franco Machado, Fernanda Marques, M. Fátima M. Piedade, M. José Villa de Brito, Maria Helena Garcia, Tânia S. Morais* XXIV Encontro Luso-Galego de Química
(Porto, Portugal)
2019/06/24 |Invited| Progress on the design of metal-based drugs for cancer therapy_M. Helena Garcia, Tânia S. Morais, Andreia Valente, Ana Isabel Tomaz 6th World Congress on Natural Product & Synthetic Chemistry (Synthetic Chemistry 2019)
(New York, United States)
2018/10/18 |Flash presentation| Synthesis and characterization of promising anticancer Cu(I) complexes_João Franco Machado, Fernanda Marques, M. Fátima M. Piedade, Maria Helena Garcia, Tânia S. Morais* MMSE 2018 - Modern Methods of Structure Elucidation
(Lisbon, Portugal)
2017/05 |Invited| Ruthenium compounds as metallodrug candidates for cancer therapy_Ana Isabel Tomaz, Andreia Valente, Tânia S. Morais, Fernanda Marques, M. Helena Garcia BIT's 10th Annual World Cancer Congress 2017 (WCC2017)
(Barcelona, Spain)
2017 "Peptides as therapeutic agents"_Tânia S. Morais | lecture on Biochemistry I from the 1st academic year of Sciences and Health Course, Faculdade de Ciências da Universidade de Lisboa, 2017 lecture on Biochemistry I from the 1st academic year of Sciences and Health Course
aculdade de Ciências da Universidade de Lisboa (Lisbon, Portugal)
2016/11 |Invited| Ruthenium new drugs: a promising future in cancer therapy? _M. Helena Garcia, Andreia Valente, Tânia S. Morais, Ana Isabel Tomaz World Congress on Cancer Research & Therapy
(Miami, United States)
2016/09/16 |Keynote| Ruthenium Drugs: a break in the wall_Tânia S. Morais Lilly CASE award day, Lilly UK pharmaceuticals
Lilly UK pharmaceuticals (WIndlesham, United Kingdom)
2016/06 |Invited| Ruthenium Organometallic compounds as promising antimetastatic drugs for breast cancer chemotherapy_M. Helena Garcia, Andreia Valente, Tânia S. Morais, Fernanda Marques European Chemistry Congress
(Rome, Italy)
2016 "Carbohydrates. Classification of carbohydrates. Polysaccharides of structure and storage."_Tânia S. Morais | lecture on Biochemistry I from the 1st academic year of Sciences and Health Course, Faculdade de Ciências da Universidade de Lisboa, 2016 lecture on Biochemistry I from the 1st academic year of Sciences and Health Course
Faculdade de Ciências da Universidade de Lisboa (Lisbon, Portugal)
2015/11 |Invited| Ruthenium drugs for cancer therapy: small structural changes, different in vivo performances M. Helena Garcia, Tânia S. Morais, Ana Isabel Tomaz, Fernanda Marques, Andreia Valente 4th International Conference on Medicinal Chemistry & Computer Aided Drug Designing
(Atlanta, United States)
2015/06 New ruthenium cyclopentadienyl thiosemicarbazone compounds with antiproliferative activity on pathogenic trypanosomatid parasites_Esteban Rodríguez Arce, Mariana Fernández, Cynthia Sarniguet, Tânia S. Morais, Ana Isabel Tomaz, Claudio Olea Azar, Roberto Figueroa, J. Diego Maya, Andrea Medeiros, Marcelo Comini, M. Helena García, Lucía Otero and Dinorah Gambino 13th International Symposium on Applied Bioinorganic Chemistry (ISABC13)
(Galway, Ireland)
2014/12/01 | Invited| Targeting tumors with innovative ruthenium peptide complexes_Tânia S. Morais CQE Young Researchers Day
(Lisbon, Portugal)
2014/12 |Invited| Tracking antitumor drugs: ruthenium(II) cyclopentadienyl complexes as promising agents _M. Helena Garcia, Tânia S. Morais, Andreia Valente, Fernanda Marques 3rd International Conference on Medicinal Chemistry & Computer Aided Drug Designing
(San Francisco, United States)
2014/11/27 Novos compostos organometálicos de ruténio na terapia do cancro_Tânia S. Morais, M. Helena Garcia XX Encontro Luso-Galego de Química
(Porto, Portugal)
2014/10 Ruthenium-based anticancer compounds: Insights into their uptake mechanisms and cellular targets_Fernanda Marques, Leonor Côrte-Real, Tânia S. Morais, Manuel Bicho, Maria Helena Garcia, António Matos 4th World Congress on Cancer Science & Therapy
(Chicago, United States)
2014/05/01 |Invited| New compounds, big challenges _Tânia S. Morais 4th Portuguese Young Chemist Meeting
(Coimbra, Portugal)
2014/03/26 Evaluation of the potential anti-tumoral properties of new ruthenium bioorganometallic compounds_Tânia S. Morais CCMM Seminars
(Lisbon, Portugal)
2013/09 Novel Pathways for Anticancer Therapy: the Role of Golgi network in the mechanism of cell death of organometallic complexes_Fernanda Marques, António P. Matos, Leonor Côrte-Real, Tânia S. Morais, Ana Isabel Tomaz, M. Helena Garcia, Manuel P. Bicho Microscopy at the Frontiers of Science, 2013: 3rd Joint Congress of the Portuguese and Spanish Microscopy Societies and Israel Society for Microscopy
(Tarragona, Spain)
2012/11 Promising organometallic ruthenium metallodrugs: RuII(¿5-C5H5)(bipy)(PPh3)]+ a promising large spectrum antitumor agent_Ana Isabel Tomaz, Tamás Jakusch, Tânia S. Morais, Rodrigo F. M. de Almeida, Fernanda Marques, Filipa Mendes, Éva A. Enyedy, M. Helena Garcia 3rd National Meeting on Medicinal Chemistry
(Aveiro, Portugal)
2012/09 Intracellular distribution of antitumor Ru(II) compounds: the lysossome and the lysosomal enzymes as targets for anticancer metal-based drugs_Fernanda Marques, Leonor Côrte-Real, António Matos, Irina Alho, Tânia S. Morais, Ana Isabel Tomaz, M. Helena Garcia, Manuel P. Bicho XLVI Congress of the Portuguese Society for Microscopy
(Lisbon, Portugal)
2011/09 A promising large spectrum new antitumor ruthenium agent: interaction with serum proteins ad mechanisms of cell death_Ana Isabel Tomaz, Tamás Jakusch, Tânia S. Morais, Rodrigo F. M. de Almeida, Fernanda Marques, Filipa Mendes, Éva A. Enyedy, João Costa Pessoa, Tamás Kiss, M. Helena Garcia 4th European Conference on Chemistry for Life Sciences
(Budapest, Hungary)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2021/11 - Current Novos complexos de ruténio contendo antibióticos como potenciais agentes anticancerígenos bifuncionais
Supervisor of Bárbara Marques
Química (Degree)
Universidade de Lisboa Faculdade de Ciências, Portugal
2021/11 - Current Síntese de novos glicoconjugados no combate a infeções causadas por bactérias Gram negativas multirresistentes
Co-supervisor of Rita Almeida
Química (Degree)
Universidade de Lisboa Faculdade de Ciências, Portugal
2021/09 - Current Desenvolvimento de novos conjugados ruténio-péptido para a terapia seletiva do cancro da mama metastático
Supervisor of Joana Neves Duarte
Química (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2019 - Current Novos conjugados ruténio-péptido para a terapia seletiva do cancro a mama metastático
Supervisor of João Miguel Franco Machado
Química (PhD)
Universidade de Lisboa Faculdade de Ciências, Portugal
2020 - 2021 New organometallic ruthenium complexes for breast cancer treatement
Supervisor of Marco Sá
Química (Degree)
Universidade de Lisboa Faculdade de Ciências, Portugal
2019/11 - 2020 Development of new inorganic Cu(I) complexes with potential application as anti-tumor agents
Supervisor of Maria Joana Lourenço
Química (Degree)
Universidade de Lisboa Faculdade de Ciências, Portugal
2019 - 2020 Synthesis of copper(I) complexes with potential anti-tumor application
Supervisor of Inês Dias Ribeiro
Química Tecnológica (Degree)
Universidade de Lisboa Faculdade de Ciências, Portugal
2018 - 2019 Evaluation of Cu(I) compounds as novel chemotherapeutic agents
Co-supervisor of Diogo Sequeira
Genética Molecular e Biomedicina (Master)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018 - 2019 Development of copper(I) complexes containing amino acids for cancer therapy
Supervisor of Vanessa Wilson
Química (Degree)
Universidade de Lisboa Faculdade de Ciências, Portugal
2018 - 2019 Development of copper(I) complexes for cancer therapy
Supervisor of Raquel Ferro
Química Aplicada (Degree)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018 - 2018 Synthesis of Cu (I) and Fe(II) complexes with potential anti-tumor application
Supervisor of Magdalena Sobieska
Erasmus + program (Portugal - Poland) - 2 month internship (Other)
Universidade de Lisboa Faculdade de Ciências, Portugal
2017 - 2018 Síntese de complexos de Cu(I) e Fe(II) com potencial aplicação anti-tumoral
Supervisor of Catarina Bravo
Química (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2016 - 2017 Desenvolvimento e produção de um medicamento: da abordagem da síntese laboratorial ao processo industrial
Supervisor of David Silva Rodrigues Alves
Química Tecnológica (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2015 - 2016 Synthesis of new ruthenium organometallic complexes functionalized with sugars for selective cancer therapy
Supervisor of Francisco Manuel Silvestre
Química Tecnológica (Degree)
Universidade de Lisboa Faculdade de Ciências, Portugal
2015 - 2015 Synthesis of copper(I) complexes with potential antitumor applications
Supervisor of Yann Jousseaume
Química (Degree)
Universidade de Lisboa Faculdade de Ciências, Portugal
2014 - 2015 Synthesis of copper and iron complexes with potential antitumor application
Co-supervisor of João Lopes
Química (Degree)
Universidade de Lisboa Faculdade de Ciências, Portugal
2014 - 2015 Synthesis of new ruthenium organometallic complexes with phosphates derived from sugars for potential application in selective therapy in cancer treatment
Supervisor of Rui Miguel Freitas
Química Tecnológica (Degree)
Universidade de Lisboa Faculdade de Ciências, Portugal
2013 - 2014 Synthesis of new organometallic complexes with potential application in the treatment of gliomas
Supervisor of David Alves
Química Tecnológica (Degree)
Universidade de Lisboa Faculdade de Ciências, Portugal

Event organisation

Event name
Type of event (Role)
Institution / Organization
2022/01 - Current Member of the Organising and Scientific Committee of the 4th edition of the CQE Days " Spring Meeting 20221" (2022/05)
Conference (Member of the Scientific Committee)
Universidade de Lisboa Centro de Química Estrutural, Portugal
2020/01 - Current "Chem Forum@FCUL Centro de Química Estrutural" seminars: monthly scientific seminars of Centro de Química Estrutural, covering several topics of Chemistry (since 2020) (2020/01)
Seminar (Member of the Organising Committee)
Universidade de Lisboa Centro de Química Estrutural, Portugal
2022/02/01 - 2022/02/23 Member of the organizing committee of the meeting "Confiança na Ciência: o panorama em Portugal e no mundo" (2022/02/23 - 2022/02/23)
Round table (Member of the Organising Committee)
Universidade de Lisboa Faculdade de Ciências, Portugal
2021/05/01 - 2021/09/24 Organization of CQE participation at European Researchers Night 2021 (2021/09/24 - 2021/09/24)
Festival (Member of the Organising Committee)
Universidade de Lisboa Centro de Química Estrutural, Portugal
2021/02 - 2021/05/31 Member of the Organising and Scientific Committee of the 3rd edition of the CQE Days " Spring Meeting 2021" (2021/04/27 - 2021/04/28)
Conference (Member of the Scientific Committee)
Universidade de Lisboa Centro de Química Estrutural, Portugal
2020/01 - 2020 Global Summit on Cancer Research and Therapy (https://www.thescientistt.com/cancer-research-therapy/) (2020/10/29 - 2020/10/30)
Conference (Member of the Organising Committee)
2019/01/01 - 2019/11/30 "International Year of Periodic Table 2019, celebrate 150 years _DQB-FCUL" Member of the Organising Committee for several events from January to November 2019 (2019/01/01 - 2019/11/30)
Other (Member of the Organising Committee)
Universidade de Lisboa Faculdade de Ciências, Portugal
2019/02 - 2019/05 Member of the Organising and Scientific Committee of the 1st edition of the CQE Days " Spring Meeting 2019 "(https://cqe.tecnico.ulisboa.pt/cqedays) (2019/05/30 - 2019/05/31)
Conference (Member of the Scientific Committee)
Universidade de Lisboa Centro de Química Estrutural, Portugal
2017/10/01 - 2018/07/19 Member of the Organising Committee of the 29th International Carbohydrate Symposium (http://www.ics2018.eventos.chemistry.pt/) (2018/07/15 - 2018/07/19)
Congress (Member of the Organising Committee)
Universidade de Lisboa Faculdade de Ciências, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2011/01 - 2021/12 | Outreach Activities | Participation in several activities that promote interaction between the community and FCUL: Verão ULisboa (years 2018, 2019); Dia Aberto DQB, FCUL (years 2018, 2019); Ser Cientista, FCUL (year 2016); Open Lab Days to secondary school students (since 2011 to 2021); Dia Aberto, FCUL (since 2009 to 2021); Scientist Speed Dating @ DQB (2019); SPEED DATING com os cientistas at FCUL (2019)
Other
Several activities that promote interaction between the community and FCUL
Universidade de Lisboa Faculdade de Ciências, Portugal
2021/07 - 2021/09 "EIT Innostars Awards Bootcamp 2021" | training in the area of entrepreneurship/objective was support researchers in assessing the commercial potential of their products/technologies. 4 weeksCourse/ tutorials and practical exercises on topics: communication and marketing, intellectual property, development of a business plan, financing opportunities, pitching techniques, team management and approaching investors.
Workshop
EIT Innostars Awards Bootcamp 2021
2020/11/27 - 2020/11/30 | Outreach Activity | Participation in the European Researchers' Night with the video "Podem os metalofármacos ser uma boa aposta para a terapia do cancro?" - Festival de Curtas - Química para Todos@ULisboa; Vídeo disponível em: https://www.youtube.com/watch?v=Dea38ODk6T4&feature=emb_logo
Exhibition
European Researchers' Night 2020
European Commission, Belgium
2019/01/29 - 2019/01/29 | Outreach Activity | IYPT -International Year of the PeriodicTable | Flashmob Flash mob involving both students andprofessors/researchers, each identified as an Element of thePeriodic Table and performed on the Periodic Table paint located on the entrance of C8 building -FCUL. The event was filmed by air and on the ground.https://photos.app.goo.gl/t9o8aTYdreixDTjh7;http://iypt2019.campus.ciencias.ulisboa.pt/index.html ;https://youtu.be/bmVMJoynb1Q
Exhibition
FlashMob | Cerimónia de abertura do Ano Internacional da Tabela Periódica 2019
Universidade de Lisboa Faculdade de Ciências, Portugal
2014/05/12 - 2014/05/12 Complementary Training - "Egas Moniz Symposium on Electron Microscopy, An Overview of Scientific Applications"
Symposium
Egas Moniz Cooperativa de Ensino Superior CRL, Portugal
2011/10/10 - 2011/10/15 1st International Summer School on Modern Chemistry
Workshop
Universidade de Lisboa Faculdade de Ciências, Portugal
2010/12/13 - 2010/12/17 Complementary Training - Modern Methods of Structure and Elucidation 2010 (theoretical and practical components)
Workshop
Universidade de Lisboa Instituto Superior Técnico, Portugal
2009/12/03 - 2009/12/03 Complementary Training - Brucker NMR users meeting-Portugal 2009
Meeting
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2009/12/02 - 2009/12/02 Complementary Training -Biomolecular NMR from liquids to solids
Meeting
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal

Jury of academic degree

Topic
Role
Candidate name (Type of degree)
Institution / Organization
2021/12/16 New multifunctional drug delivery systems for cancer therapy via innovative polymerization strategies
(Thesis) Main arguer
Adhan Pilon (PhD)
Universidade de Lisboa Faculdade de Ciências, Portugal
2021 President of Jury: Final project 1st Cycle in Chemistry, Faculty of Sciences of the University of Lisbon
President of the jury
Number of Juries as President in 2021 = 11 (Other)
Universidade de Lisboa Faculdade de Ciências, Portugal
2021 Member of Jury: Final project 1st Cycle in Chemistry, Faculty of Sciences of the University of Lisbon
Thesis Member
Number of Juries as Member in 2021 = 17 (Other)
Universidade de Lisboa Faculdade de Ciências, Portugal
2020/07 New ruthenium complexes containing derivatized benzonitriles as potential anti-cancer agents
(Thesis) Arguer
Jorge Valentim (Other)
Universidade de Lisboa Faculdade de Ciências, Portugal
2020 2020 -President of Jury: Final project 1st Cycle in Chemistry, Faculty of Sciences of the University of Lisbon
President of the jury
Number of Juries as President in 2020 = 3 (Other)
Universidade de Lisboa Faculdade de Ciências, Portugal
2020 Member of Jury: Final project 1st Cycle in Chemistry, Faculty of Sciences of the University of Lisbon
Thesis Member
Number of Juries as Member in 2020 = 5 (Other)
Universidade de Lisboa Faculdade de Ciências, Portugal
2019/07 Study of the degradation and detection of pollutants
(Thesis) Main arguer
Duarte Antunes (Other)
Universidade de Lisboa Faculdade de Ciências, Portugal
2019/07 Synthesis of new complexes of endogenous metals with anticancer potential
(Thesis) Main arguer
Beatriz Filipa Afonso Moreno (Other)
Universidade de Lisboa Faculdade de Ciências, Portugal
2019/06 Synthesis and biological evaluation of a peptide containing a TRAF6-binding sequence
(Thesis) Main arguer
Susana Catapirra Magessi Ferreira (Other)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018/07 New Fe (III) and Co (II) Complexes with Ligands Derived from Hydrazides
(Thesis) Main arguer
Rafaela Farelo Silva Tenera Marques (Other)
Universidade de Lisboa Faculdade de Ciências, Portugal

Association member

Society Organization name Role
2020/05 - Current Royal Society of Chemistry Member
2016 - Current The American Association for Advance of Science Member
2016 - Current Marie Curie Alumni Association Member
2015 - Current College of Chemistry of ULisboa Member
2001 - Current Sociedade Portuguesa de Química Member

Committee member

Activity description
Role
Institution / Organization
2022/01 - Current Member of Community "Comunicadores de Ciência em Ciências"
Member
Universidade de Lisboa Faculdade de Ciências, Portugal
2021/12 - Current Member of Spain-Portugal Chapter of Marie Curie Alumni Association
Member
2020/01 - Current Member of communication and image committee of CQE
Member
Universidade de Lisboa Centro de Química Estrutural, Portugal
2020/02/01 - 2021/12/31 Member of the comission responsible for the mensal CQE Newsletter (since Jan 2020- Dez 2021)
Member
Universidade de Lisboa Centro de Química Estrutural, Portugal

Conference scientific committee

Conference name Conference host
2022/01 - Current Member of scientific committee of 4th edition of the CQE Days "Spring Meeting 2022" Lisbon, Portugal
2021/02/01 - 2021/05/31 Member of scientific committee of 3rd edition of the CQE Days "Spring Meeting 2021" Centro de Química Estrutural
2019/02/01 - 2019/05/31 Member of scientific committee of 1st edition of the CQE Days "Spring Meeting 2019" Lisboa, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2022/02 - Current 44450 - Aplicações da Química Inorgânica na Vida Quotidiana (typology: T + TP)| academic years: 2020/2021 - Present Química (Licenciatura) Universidade de Lisboa Faculdade de Ciências, Portugal
2019/02 - Current 44310 - Bioquímica Inorgânica/Inorganic Biochemistry (typology: TP)| academic years: 2018/2019, 2019/2020 Bioquímica (Licenciatura) Universidade de Lisboa Faculdade de Ciências, Portugal
2018/09 - Current 44425 - Química Inorgânica Complementar/Complementary Inorganic Chemistry (typology: P)| academic years: 2018/2019 - present Química (Licenciatura) Universidade de Lisboa Faculdade de Ciências, Portugal
2018/02 - 2018/07 44432 - Química Inorgânica/Inorganic Chemistry (typology: P)| academic years: 2017/2018 Química (Licenciatura) Universidade de Lisboa Faculdade de Ciências, Portugal
2018/02 - 2018/07 44385 - Laboratório de Sínteses e Desenvolvimento de Productos/Laboratory of Synthesis and Development of Products (typology: P)| academic years: 2017/2018 Química Tecnológica (Licenciatura) Universidade de Lisboa Faculdade de Ciências, Portugal
2016/02 - 2017/07 10001 - Bioquímica/Biochemistry (typology: P)| academic years: 2015/2016, 2016/2017 Ciências da Saúde (Licenciatura) Universidade de Lisboa Faculdade de Ciências, Portugal
2014/02 - 2015/07 44337 - Bioquímica/Biochemistry (typology: P)| academic years: 2013/2014, 2014/2015 Biologia (Licenciatura) Universidade de Lisboa Faculdade de Ciências, Portugal

Evaluation committee

Activity description
Role
Institution / Organization Funding entity
2021/01 - Current Accompanying commission of Mohannad Yousellf, PhD student in Biochemistry, Faculdade de Ciências, Universidade de Lisboa. Thesis entitled "Adding pH effects to improve computer-aided drug design"
Evaluator
Universidade de Lisboa Faculdade de Ciências, Portugal
2019/01 - Current Accompanying commission of Adhan Pilon, PhD student in Chemistry, Faculdade de Ciências, Universidade de Lisboa. Thesis entitled "New multifunctional drug delivery systems for cancer therapy via innovative polymerization strategies"
Evaluator
Universidade de Lisboa Faculdade de Ciências, Portugal

Interview (tv / radio show)

Program Topic
2020/12/11 - Current Program 90 segundos de ciência, Antena 1 radio "Investigadora Tânia Morais, Investigação Desenvolve Composto Para Tratar O Cancro Da Mama Triplo Negativo, 90 segundos de ciência" Tânia Morais – Investigação Desenvolve Composto Para Tratar O Cancro Da Mama Triplo Negativo - EPS 980

Journal scientific committee

Journal title (ISSN) Publisher
2021/01 - Current Chemical Papers Springer Nature
2021 - Current Polyhedron Elseviers
2021 - Current Acta Chimica Slovenica Slovenian Chemical Society
2021 - Current Biomedicines (2227-9059) MDPI
2021 - Current Chemistry (2624-8549) MDPI
2021 - Current Science of the Total Environment (0048-9697) Elsevier
2021 - Current Biometals Springer
2021 - Current Nanomaterials (2079-4991) MDPI
2021 - Current Frontiers in Oncology Frontiers
2020/12 - Current Molecules (1420-3049) MDPI
2020/11 - Current Pharmaceuticals (1424-8247) MDPI
2020/09 - Current Frontiers in Chemistry
2020/01 - Current Dalton Transactions Royal societry of Chemistry
2019/08 - Current Inorganica Chimica Acta (0020-1693) Elsevier
2019/03 - Current Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Elsevier
2018/11 - Current Current Medicinal Chemistry (0929-8673) Bentham Science
2018/11 - Current Medicinal Chemistry (1875-6638) Bentham Science Publishers
2018/10 - Current Anti-Cancer Agents in Medicinal Chemistry Bentham Science Publishers
2018 - Current Journal of Chemistry Hindawi
2015 - Current International Journal of Molecular Sciences (1422-0067) MDPI AG
2014/11 - Current Advances in Chemistry (2314-7571) Hindawi Limited
Distinctions

Award

2016 Granted with an honorarium by Lilly UK pharmaceuticals
Lilly UK pharmaceuticals , United Kingdom
2015 First prize in ScienceIN2Business Initiative, TecLabs for Translational Research, 2015 (M. Helena Garcia, Andreia Valente, Tânia S. Morais, A. Isabel Tomaz, "Rupharma")
TecLabs , Portugal
2014 Portuguese Young Chemist Award 2014 (PYC-Gradiva 2014)
Sociedade Portuguesa de Química, Portugal
2013 Best poster prize - Drug Discovery & Therapy World Congress, 2013, M. Helena Garcia, Tânia S. Morais, Ana Isabel Tomaz, Andreia Valente, Fernanda Marques, "Cyclopentadienyl ruthenium (macro)metallodrugs: large spectrum antitumor agents"
Drug Discovery & Therapy World Congress, United States

Title

2021 Lead Guest Editor of the special issue "Rational Drug Design of Metal Complexes for Cancer Therapy" from Frontiers in chemistry since 2021 to present
2021 Acting as guest editor for Chemistry, MDPI (2021)
2021 Guest Associate Editor Medicinal and Pharmaceutical Chemistry Frontiers
2020 Lead Guest Editor of the special issue "Target-Specific Delivery of Gold and Ruthenium Complexes to Cancer Cells: Where Are We?" from Molecules, MDPI since 2020 to present
2020 Member of "Topical Advisory Panel of Molecules MDPI" (https://www.mdpi.com/journal/molecules/topic_editors)_since 2020
2020 Member of "Topical Advisory Panel of Pharmaceutics MDPI" (https://www.mdpi.com/journal/pharmaceutics/topic_editors)_since 2020
2019 Guest Editor of the special issue "1st CQE Days Meeting: 44 Years Connecting People and Chemistry" from Molecules, MDPI since May 2009 to April 2020 (https://www.mdpi.com/journal/molecules/special_issues/CQE_days_meeting)
2019 Acting as guest editor for Anti-Cancer Agents in Medicinal Chemistry, Bentham Science (2019)
2018 Acting as guest editor for Journal of Chemistry, Hindawi (2018)
2017 Member of editorial board of Journal of Pharmacology and Pharmaceutical Research
2016 Nominated for participation in the AAAS/science program for Excellence in Science (The American Association for Advance of Science)
The American Association for Advance of Science, United States

Other distinction

2022 Invitation to publish a Perspective Review_Dalton Trans. 2022 - "Are smart delivery systems the solution to overcome the lack of selectivity of current metallodrugs in cancer therapy?"
2020 Paper Dalton Trans., 2020, 49, 12273-12286. Selected as HOT TOPIC (October2020)
2017 |Media Citation| "Novo complexo de Ruténio inibe o desenvolvimento de metástases in vivo", Website ASPIC
2017 |Media Citation| "In vivo Performance of a Ruthenium-cyclopentadienyl Compound in an Orthotopic Triple Negative Breast Cancer Model", Website ASPIC
2017 |Media Citation| "Novos complexos de cobre(I) e cobre(I)-ruténio(II) promissores para a terapia do cancro", Website ASPIC
2017 9th place (in 25) on the "most downloaded papers in last 90 days" from J. Inorg. Biochem., with the paper Journal of Inorganic Biochemistry, 169, 2017, 68-78, June 2017.
2014 |Media Citation| "Tânia Morais galardoada com o Portuguese Young Chemists Award", Website Diário Digital
2014 |Media Citation| "Pós-doutorada da ULisboa distinguida com Portuguese Young Chemists Award 2014", Website ULisboa
2014 |Media Citation| "Tânia Morais identificou compostos eficientes contra várias linhas celulares cancerígenas", Website TVciência
2014 |Media Citation| "Tânia Morais identificou compostos eficientes contra várias linhas celulares cancerígenas", Website PortugalNews
2014 |Media Citation| "Investigadora recebe «Portuguese Young Chemists Award» pelo trabalho «Novos compostos, grandes desafios»", Website Diário Digital
2014 |Media Citation| "Jovens cientistas: Tânia S. Morais" Website FCUL
2014 1st place (in 25) on the "most downloaded papers in last 90 days" from J. Inorg. Biochem., with the paper Journal of Inorganic Biochemistry, 130, 2014, 1-14, February 2014.
2014 6th place (in 25) on the "most downloaded papers in last 90 days" from J. Inorg. Biochem., with the paper Journal of Inorganic Biochemistry, 129, 2013, 1 - 8, January 2014.
2013 |Media Citation| "1º Prémio no "Drug Discovery & Therapy World Congress 2013"
2013 |Media Citation| "Cancro: Portuguesas vencem prémio mundial nos EUA"
2013 |Media Citation| In the Portuguese News/TVI television channel "Jornal da 8(TVI): Os comentários do Prof. Marcelo Rebelo de Sousa"
2013 11th place (in 25) on the "most downloaded papers in last 90 days" from J. Inorg. Biochem., with the paper Journal of Inorganic Biochemistry, 122, 2013, 8 ¿ 17, March 2013.