???global.info.a_carregar???
Rita Cascão received her degree in Biology, Microbiology and Genetics (Faculdade de Ciências, Universidade de Lisboa) in 2005 and finished her masters in Molecular Biology and Genetics (Faculdade de Ciências, Universidade de Lisboa) in 2007. She obtained her PhD degree in Biomedical Sciences/Immunology (Faculdade de Medicina, Universidade de Lisboa) in 2012. Her PhD work, funded by an FCT fellowship, was developed at Instituto de Medicina Molecular João Lobo Antunes (iMM) under the supervision of Prof. João Eurico Fonseca. From 2012 to 2014, Rita Cascão worked at the Biobanco-iMM, where she contributed to the establishment of the Brain Tumour Bank, in collaboration with Prof. Cláudia Faria (a senior clinician-scientist). During this time, she received training in patient-derived cell cultures from patients with brain tumours at the Labatt Brain Tumour Research Centre (The Hospital for Sick Children, Canada). Between 2014 and 2018, Rita Cascão worked as a postdoctoral fellow in the field of autoimmune diseases at the laboratory of Prof. João Eurico Fonseca (iMM). In 2018, she changed the field of expertise, and joined the laboratory of Prof. João Barata (iMM), as a senior postdoctoral researcher, to work in close collaboration with Prof. Cláudia Faria in a team fully dedicated to the study of brain tumours, with several funded projects. Rita Cascão is currently an assistant researcher (CEEC ref: 2023.09105.CEECIND) with 1 book chapter and 29 manuscripts published in peer review journals (Research Gate source - total citation number: 1,147 and h-index: 15), with 12 out of 30 as first author, and 2 as corresponding author. Rita Cascão has 21 oral communications in conferences and more than 50 poster publications in national and international meetings. Rita Cascão also has experience in the supervision of undergraduate (1), IEFP (1), GAPIC (3), master (6) and PhD students (3) and was scientific adviser in PhD thesis committees (2). Rita Cascão is also invited for main arguer in evaluation juries and as reviewer for several international scientific journals. She has participated in 12 projects as a team member, including FCT and European funded projects, and received 1 award for scientific merit. Rita Cascão also has expertise in biobanking and experience working with pharmaceutical and biotechnological companies (namely for the development and preclinical trials of new compounds/therapies), which are crucial skills for the projects that she is currently carrying out. During her scientific career she has participated in several courses, most importantly the: Training in primary cell culture at Dr. Peter Dirks lab, and in Stem cell culture at Embryonic Stem Cell Facility, Arthur and Sonia Labatt Brain Tumour Research Centre, Canada; Course in Histology and histopathology in biomedical translational research, iMM, Portugal; Course in Animal Experimentation, certified by Direcção Geral de Veterinária, IMM, Portugal (Procedures and Project design). Rita Cascão scientific research is currently focused on advancing the knowledge of the mechanisms underlying brain metastization to identify genetic drivers of brain metastases, which could be used as clinical biomarkers of disease progression and new therapeutic targets. The patient-based translational strategy of this research has the potential to effectively address the lack of therapies for the treatment of patients with brain tumours, improving their quality of life and survival. This line of research has intellectual property (IP) and technology transfer potential. She has also been involved in a work dedicated to the study of medulloblastoma dissemination and glioblastoma relapse. Rita Cascão engages in Science Outreach activities, participating in the organization of the Brain Tumour Team (BTT) running and social events, in RAISE activities, and giving lectures to high schools students, to create awareness and fundraise for brain tumour research at iMM.
Read full resume ↓
Identification

Personal identification

Full name
Ana Rita Cascão Rodrigues

Citation names

  • Cascão, Rita
  • Cascao, R

Author identifiers

Ciência ID
B616-D8BB-3CF2
ORCID iD
0000-0001-5533-9413
Scopus Author Id
35728434100

Email addresses

  • ritacascao@medicina.ulisboa.pt (Professional)
  • ritacascao@gmail.com (Personal)

Telephones

Mobile phone
  • 917377069 (Personal)

Addresses

  • Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa  Avenida Professor Egas Moniz , 1649-028, Lisbon, Lisbon, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Education
Degree Classification
2023/09/01 - 2030
Ongoing
 Ciências da Vida e da Saúde (Pós-doutoramento)
Major in Oncobiology/Brain Tumours
Instituto de Medicina Molecular, Portugal
2018 - 2023/08/31
Concluded
 Ciências da Vida e da Saúde (Pós-doutoramento)
Major in Oncobiologia
Universidade de Lisboa Faculdade de Medicina, Portugal
2014 - 2018
Concluded
 Ciências da Vida e da Saúde (Pós-doutoramento)
Major in Biomedicina - Mecanismos da Doença
Universidade de Lisboa Faculdade de Medicina, Portugal
2014 - 2014
Concluded
 Course in Biosafety (IMM BSL3 Facility). (Outros)
Instituto de Medicina Molecular, Portugal
2013
Concluded
 Training in primary cell culture at Dr. Peter Dirks lab, and in stem cell culture at Embryonic Stem Cell Facility, Arthur and Sonia Labatt Brain Tumour Research Centre, Toronto, Canada. (Outros)
Arthur and Sonia Labatt Brain Tumour Research Centre, Canada
2009 - 2012
Concluded
 Ciências Biomédicas (Doutoramento)
Major in Especialidade: Imunologia
Universidade de Lisboa Faculdade de Medicina, Portugal
"Role of IL-1ß in Rheumatoid Arthritis" (THESIS/DISSERTATION)
 Distinção e Louvor
2010
Concluded
 Course in Histology and histopathology in biomedical translational research, IMM, Lisbon, Portugal. (Outros)
Instituto de Medicina Molecular, Portugal
2010
Concluded
 Course in Animal Experimentation, certified by Direcção Geral de Veterinária, IMM, Lisbon, Portugal. (Outros)
Instituto de Medicina Molecular, Portugal
2010
Concluded
 Course in Biostatistics, IMM, Lisbon, Portugal. (Outros)
Instituto de Medicina Molecular, Portugal
2010
Concluded
 Course in Microscopy, IMM, Lisbon, Portugal. (Outros)
Instituto de Medicina Molecular, Portugal
2008
Concluded
 Course in Biology of Cancer, IMM, Lisbon, Portugal. (Outros)
Instituto de Medicina Molecular, Portugal
2008
Concluded
 Course in Flow Cytometry, IMM, Lisbon, Portugal. (Outros)
Instituto de Medicina Molecular, Portugal
2008
Concluded
 Course in Ethics and Scientific Integrity, IMM, Lisbon, Portugal (Outros)
Instituto de Medicina Molecular, Portugal
2008
Concluded
 Course in miRNAs and non-coding RNAs in cell biology and human disease, IMM, Lisbon, Portugal. (Outros)
Instituto de Medicina Molecular, Portugal
2008
Concluded
 Course in Challenges in immunology, IMM, Lisbon, Portugal. (Outros)
Instituto de Medicina Molecular, Portugal
2006 - 2007
Concluded
 Mestrado em Biologia Molecular e Genética (Mestrado)
Major in Molecular Biology and Human Genetics
Universidade de Lisboa Faculdade de Ciências, Portugal
"Epidemiologia molecular da Surdez Hereditária: Prevalência das variantes patogénicas do gene GJB2 identificadas em famílias Portuguesas" (THESIS/DISSERTATION)
 17
2005 - 2006
Concluded
 Especialização em Biologia (Pós-Graduação)
Major in Molecular Biology and Human Genetics
Universidade de Lisboa Faculdade de Ciências, Portugal
 18
2001 - 2005
Concluded
 Biologia Microbiana e Genética (Licenciatura)
Major in Biology (Microbiology and Genetics)
Universidade de Lisboa Faculdade de Ciências, Portugal
 15
Affiliation

Science

Category
Host institution 		Employer
2023/09/01 - 2030 Postdoc (Research) Instituto de Medicina Molecular, Portugal
Instituto de Medicina Molecular, Portugal
2018 - 2023/08/31 Postdoc (Research) Instituto de Medicina Molecular, Portugal
Universidade de Lisboa Faculdade de Medicina, Portugal
2014 - 2018 Postdoc (Research) Instituto de Medicina Molecular, Portugal
Universidade de Lisboa Faculdade de Medicina, Portugal
2012 - 2014 Postdoc (Research) Instituto de Medicina Molecular, Portugal
Universidade de Lisboa Faculdade de Medicina, Portugal
2013/03/01 - 2013/08/31 Postdoc (Research) Instituto de Medicina Molecular, Portugal
Universidade de Lisboa Faculdade de Medicina, Portugal
2007 - 2009 Researcher (Research) Instituto de Medicina Molecular, Portugal
Universidade de Lisboa Faculdade de Medicina, Portugal

Others

Category
Host institution 		Employer
2009 - 2012 PhD student Instituto de Medicina Molecular, Portugal
Universidade de Lisboa Faculdade de Medicina, Portugal
Projects

Grant

Designation Funders
2023/01/01 - 2025/12/31 Exploiting UBE2C as a prognostic marker and therapeutic target in human brain metastases
2022.08774.PTDC
Post-doc
Instituto de Medicina Molecular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2022 - 2024 UBE2C as a prognostic marker and therapeutic target in patients with breast cancer brain metastases
17859
Researcher
Instituto de Medicina Molecular, Portugal
Ongoing
2021 - 2022 Clinical validation of CCL2/CCR2 signaling pathway in metastatic medulloblastoma
N/A
Researcher
Universidade de Lisboa Faculdade de Medicina, Portugal
 Liga Portuguesa Contra o Cancro
Concluded
2021 - 2021 Clinical validation of molecular targets involved in glioblastoma recurrence
n.º 20210029
Supervisor
Universidade de Lisboa Faculdade de Medicina, Portugal
Concluded
2018 - 2021 Using genomics to identify novel targeted therapies in brain metastases
PTDC/MED-ONC/32222/2017
Researcher
Fundação para a Ciência e a Tecnologia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016 - 2018 Carbon monoxide guided shuttles (COGSs) to fight Rheumatoid Arthritis
PTDC/QEQ-MED/1902/2014
Researcher
Fundação para a Ciência e a Tecnologia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2013 - 2013 Role of ASF/SF2 and SRp20 in IL-1ß secretion
PTDC/SAU-MII/100780/2008
Post-doc Fellow
Fundação para a Ciência e a Tecnologia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2009 - 2011 Development of carbon monoxide releasing molecules for the treatment of rheumatoid arthritis (COMRA).
FP7-SME-2008-1
Researcher
Community Research and Development Information Seventh Framework Programme Research and Innovation Security, Belgium
 Community Research and Development Information Seventh Framework Programme Research and Innovation Security
Concluded
2006 - 2007 Surdez hereditária:abordagem genética, clínica e psicológica no apoio a famílias portuguesas afectadas
RIPD/SAU-ESP/63720/2005
Master Student Fellow
Fundação para a Ciência e a Tecnologia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2018 - Current RESEARCHER HIRED UNDER THE ARTICLE 23rd FROM DECREE-LAW NR 57/2016, OF 29th AUGUST, ALTERED BY LAW NR 57/2017, OF 19th JULY
Decree-Law nr 57/2016, from 29th August, altered by Law nr 57/2017, from 19th July
Researcher
Instituto de Medicina Molecular, Portugal
Ongoing
Outputs

Publications

Book chapter
  1. Cascão, Rita; et al. "Optimizing the Role of Immunotherapy for the Treatment of Glioblastoma". In New Insights into Glioblastoma Diagnosis, Therapeutics and Theranostics, edited by Carla Vitorino, Carmen Balana, Célia Cabral. Elsevier, 2023.
    Published
Conference abstract
  1. Cascão, R; Carvalho, T; Goncalves, J; Moita, LF; Fonseca, JE. "AB0096 Efficacy and safety of oral administration of pure celastrol in aia rats". Paper presented in EULAR, Madrid, 2017.
    Published • 10.1136/annrheumdis-2017-eular.2868
  2. Rita Cascão; Bruno Vidal; João Eurico Fonseca; et al. "6: The specific inhibitor of RORgammaT transcriptional activity and Th17 polarization digoxin reduces the severity of adjuvant-induced arthritis". Paper presented in 32nd European Workshop for Rheumatology Research, Stockholm, 2012.
    Published • 10.1136/annrheumdis-2012-eular.179
  3. Rita Cascão; Bruno Vidal; João Eurico da Fonseca; et al. "A169: Gambogic acid and celastrol are two powerful anti-inflammatory drugs in arthritis". Paper presented in 31st European Workshop for Rheumatology Research, Amsterdam, 2011.
    Published • 10.1136/ard.2010.149013.12
  4. Rita Cascão; Joaquim Polido-Pereira; Helena Canhão; et al. "A4: Caspase-1 is active since the early phase of Rheumatoid arthritis.". Paper presented in 31st European Workshop for Rheumatology Research, Amsterdam, 2011.
    Published • 10.1186/1479-5876-8-S1-P35
  5. Rita A Moura; Rita Cascão; Inês Perpetuo; et al. "A192: Spondyloarthritis and Rheumatoid arthritis: different clinical manifestations, similar cytokine network.". Paper presented in 31st European Workshop for Rheumatology Research., Amsterdam, 2011.
    Published • 10.1186/1479-5876-8-S1-P36
  6. Rita Cascão; Rita A Moura; Helena Canhão; et al. "A128: CYTOKINE NETWORK IN THE FIRST 6 WEEKS OF RHEUMATOID ARTHRITIS ONSET". Paper presented in 30th European Workshop for Rheumatology Research, Bamberg, 2010.
    Published • 10.1136/ard.2010.129643e
  7. Rita Cascão; Rita A Moura; Inês Perpetuo; et al. "Cytokine profile in serum and synovial fluid of patients with established rheumatoid arthritis". Paper presented in 30th European Workshop for Rheumatology Research, Bamberg, 2010.
    Published • 10.1136/ard.2010.129643g
  8. Inês Perpetuo; Diana Carmona-Fernandes; Rita Cascão; et al. "Tumour necrosis factor antagonists and tocilizumab have a higher impact on rheumatoid arthritis osteoclastogenic stimuli than methotrexate". Paper presented in 30th European Workshop for Rheumatology Research, Bamberg, 2010.
    Published • 10.1136/ard.2010.129643p
Conference poster
  1. Carlos Custódia; Cascão, Rita; Paisana, Eunice; Daniel Picard; Marc Remke; João T. Barata; Claudia C. Faria. "Inhibition of CCR2 as a potential therapeutic approach for medulloblastoma.". Paper presented in III ASPIC- ASEICA international meeting, 2023.
  2. Carlos Custódia; Cascão, Rita; Paisana, Eunice; Daniel Piccard; Marc Remke; João T. Barata; Claudia C. Faria. "CCR2 as a potential therapeutic target to treat medulloblastoma.". Paper presented in EMBO Young Scientists’ Forum, 2023.
  3. Paisana, Eunice; Cascão, Rita; Carlos Custódia; Nan Qin; Daniel Picard; David Pauck; Tânia Carvalho; et al. "UBE2C promotes brain metastatic disease and can be a therapeutic target.". Paper presented in EMBO Young Scientists’ Forum, 2023.
  4. Eunice Paisana; Cascão, Rita; Carlos Custódia; Nan Qin; Daniel Picard; David Pauck; Tânia Carvalho; et al. "UBE2C-driven leptomeningeal dissemination can be abrogated by targeting the PI3K-mTOR pathway in patients with brain metastases". Paper presented in 2022 Annual Conference on CNS Clinical Trials & Brain Metastases, Co-Sponsored by SNO and ASCO, 2022.
  5. Cascão, Rita; Carlos Custódia; Eunice Paisana; Isidro Cortes-Ciriano; João T. Barata; Claudia C. Faria. "Patient-derived models of brain metastases are useful tools for preclinical evaluation of anticancer therapies". Paper presented in Innovative cancer Science - EACR, 2022.
  6. Carlos Custodia; Cascão, Rita; Eunice Paisana; Pedro Ruivo; José Pimentel; Rafael Roque; João T. Barata; Cláudia C. Faria. "Targeting the CCL2/CCR2 axis in metastatic meduloblastoma". Paper presented in National Conference. XV CAML· V NeurULisboa PhD Students Meeting, 2022.
  7. Paisana, Eunice; Cascão, Rita; Carlos Custódia; Nan Qin; Daniel Picard; David Pauck; Tânia Carvalho; et al. "Ubiquitin Conjugating Enzymes promote leptomeningeal dissemination and decrease survival in patients with brain metastatic disease". Paper presented in SNO 3rd Annual Conference on Brain Metastases, 2021.
  8. Paisana, Eunice; Cascão, Rita; Carlos Custódia; Nan Qin; Daniel Picard; Pedro Pereira; Rafael Roque; et al. "The Role of Ubiquitin Conjugating Enzymes in Brain Metastases". Paper presented in EACR 2021 Congress, Innovative Cancer Science: Better Outcomes through Research, 2021.
  9. Eunice Paisana; Cascão, Rita; Carlos Custódia; Nan Qin; Daniel Picard; David Pauck; Tânia Carvalho; et al. "Ubiquitin Conjugating Enzymes promote leptomeningeal dissemination and decrease survival in patients with brain metastatic disease.". Paper presented in Third Annual Conference on Brain Metastases, 2021.
  10. Eunice Paisana; Rita Cascão; et al. "The role of ubiquitin conjugating enzymes in brain metastases". Paper presented in EACR Cancer Genomics, 2019.
  11. Eunice Paisana; Rita Cascão; et al. "The role of ubiquitin conjugating enzymes in brain metastases.". Paper presented in XI Congresso Nacional da Associação Portuguesa de Neuro-Oncologia, 2019.
  12. Nan Qin; Maike Langini; Daniel Picard; Eunice Paisana; Rita Cascão; Carlos Custódia; Frauke Meyer; et al. "CELLULAR HETEROGENEITY CONTRIBUTES TO THE AGGRESSIVE BEHAVIOR OF MYC-DRIVEN MEDULLOBLASTOMA". Paper presented in Society for Neuro-Oncology’s 5th Pediatric Neuro-Oncology Basic and Translational Research Conference, 2019.
  13. Rita Cascão; et al. "Patient-derived xenografts of brain metastases: a tool for translational medicine.". Paper presented in 2nd EurOPDX workshop: "PDX models in clinical oncology and cancer precision medicine”, 2018.
  14. Cláudia C. Faria; Carlos Custódia; Eunice Paisana; Rita Cascão; João T. Barata. "Patient-derived xenograft models of brain metastases for translational medicine.". Paper presented in 3rd ASPIC, 2018.
  15. Carlos Custódia; Eunice Paisana; Rita Cascão; João T. Barata; Claudia C Faria. "An intracardiac patient-derived xenograft model of brain metastases". Paper presented in X Neurooncology, 2017.
  16. Rita Cascão; et al. "Celastrol preserves bone structure and mechanics in arthritic rats.". Paper presented in XIX CPR, 2017.
  17. Rita Cascão; et al. "Efficacy and safety of oral administration of pure celastrol in AIA rats.". Paper presented in XIX CPR, 2017.
  18. Bruno Vidal; Rita Cascão; et al. "Effects of tofacitinib in early arthritis bone loss.". Paper presented in XIX CPR, 2017.
  19. Bruno Vidal; Rita Cascão; et al. "Early arthritis induces disturbances at bone nanostructural level reflected in decreased tissue hardness.". Paper presented in XIX CPR, 2017.
  20. Bruno Vidal; Rita Cascão; et al. "Arthritis induces early bone high turnover, structural degradation and mechanical weakness.". Paper presented in European Calcificed Tissue Society Congress, 2016.
  21. Bruno Vidal; Rita Cascão; et al. "Analyzing the effects of early arthritis in systemic bone loss.". Paper presented in XVIII Congresso Português de Reumatologia, 2016.
  22. Claudia C. Faria; Carlos Custódia; Cascão, Rita; João T. Barata. "Patient Derived Xenografts from Brain Metastases of diverse primary tumors". Paper presented in I EuroPDX Workshop, 2016.
  23. Bruno Vidal; Rita Cascão; et al. "Arthritis induces early bone high turnover, structural degradation and mechanical weakness.". Paper presented in 4th Joint Meeting of the European Calcified Tissue Society (ECTS) and the International Bone and Mineral Society (IBMS), 2015.
  24. Bruno Vidal; Rita Cascão; et al. "Arthritis induces early bone high turnover, structural degradation and mechanical weakness.". Paper presented in 8th European Workshop on Immune-Mediated Inflammatory Diseases, 2014.
  25. Bruno Vidal; Rita Cascão; et al. "Arthritis induces early bone high turnover, structural degradation and mechanical weakness.". Paper presented in ACR/ARHP Annual Meeting, 2014.
  26. Saba Abdulghani; Luis Santos; Bruno Vidal; Rita Cascão; João Eurico Fonseca. "Bone mineral density distribution in early osteoporotic bone.". Paper presented in ECTS Lisbon, 2013.
  27. Rita A Moura; Rita Cascão; et al. "Phadia EliaTM system is a valuable method for RF and ACPA detection in early RA.". Paper presented in 8th International Congress on Autoimmunity, 2012.
  28. Rita Cascão; et al. "The specific inhibitor of RORgammat transcriptional activity and Th17 polarization digoxin reduces the severity of adjuvant-induced arthritis.". Paper presented in 32nd European Workshop for Rheumatology Research, 2012.
  29. Rita A Moura; Rita Cascão; et al. "Spondyloarthropathy and Rheumatoid arthritis: two different diseases, a similar cytokine network.". Paper presented in II Simpósio SPR “Artrite e Osso”, 2011.
  30. Rita A Moura; Rita Cascão; et al. "Spondyloarthropathy and Rheumatoid arthritis: two different diseases, a similar cytokine network.". Paper presented in 31st European Workshop of Rheumatology Research, 2011.
  31. Rita Cascão; et al. "Caspase-1 is active since the early phase of Rheumatoid arthritis.". Paper presented in EULAR, 2011.
  32. Rita Cascão; et al. "Caspase-1 is active since the early phase of Rheumatoid arthritis.". Paper presented in 31st European Workshop of Rheumatology Research, 2011.
  33. Rita Cascão; et al. "Caspase-1 is active since the early phase of Rheumatoid arthritis.". Paper presented in II Simpósio SPR “Artrite e osso”., 2011.
  34. Rita Cascão; et al. "Drugs that simultaneously down-regulate IL-1ß and TNF secretion significantly reduce inflammation in a rat model of adjuvant-induced arthritis.". Paper presented in Sixth European Workshop on Immune-Mediated Inflammatory Diseases, 2011.
  35. Rita Cascão; et al. "Gambogic acid and Celastrol are two powerful anti-inflammatory drugs in arthritis.". Paper presented in 31st European Workshop for Rheumatology Research, 2011.
  36. Ana F Mourão; Helena Canhão; Rita A Moura; Rita Cascão; et al. "Markers of progression to Rheumatoid Arthritis and the discriminative value of the new ACR/EULAR classification criteria for Rheumatoid Arthritis in an untreated polyarthritis cohort with less than 6 weeks of disease duration.". Paper presented in II Simpósio SPR “Artrite e Osso”, 2011.
  37. Rita Cascão; et al. "Cytokine network in the first 6 weeks of rheumatoid arthritis onset.". Paper presented in 30th European Workshop of Rheumatology Research., 2010.
  38. Rita Cascão; et al. "Cytokine network in the first 6 weeks of rheumatoid arthritis onset.". Paper presented in EULAR, 2010.
  39. Rita Cascão; et al. "Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early Rheumatoid arthritis.". Paper presented in Fifth European Workshop on Immune-Mediated Inflammatory Diseases, 2010.
  40. Rita Cascão; et al. "Caspase-1 is active since the early phase of Rheumatoid arthritis". Paper presented in Fifth European Workshop on Immune-Mediated Inflammatory Diseases, 2010.
  41. Rita A Moura; Rita Cascão; et al. "Cytokine profile in serum and synovial fluid of established rheumatoid arthritis patients". Paper presented in 30th European Workshop of Rheumatology Research., 2010.
  42. Rita A Moura; Rita Cascão; et al. "Cytokine profile in serum and synovial fluid of established rheumatoid arthritis patients.". Paper presented in EULAR, 2010.
  43. Rita A Moura; Rita Cascão; et al. "O padrão de citocinas no líquido articular da artrite reumatóide estabelecida favorece a diferenciação de células B e TH17.". Paper presented in XV Congresso Português de Reumatologia, 2010.
  44. Rita A Moura; Rita Cascão; et al. "Cytokine pattern in very early Rheumatoid arthritis favours B cell activation and survival.". Paper presented in Fifth European Workshop on Immune-Mediated Inflammatory Diseases., 2010.
  45. Rita A Moura; Rita Cascão; et al. "Spondyloarthropathy and Rheumatoid arthritis: two different diseases, a similar cytokine network.". Paper presented in Fifth European Workshop on Immune-Mediated Inflammatory Diseases, 2010.
  46. Inês Perpetuo; Diana Fernandes; Rita Cascão; et al. "TNF Antagonists and tocilizumab have a higher impact on rheumatoid arthritis osteoclastogenic stimuli than methotrexate.". Paper presented in 30th European Workshop of Rheumatology Research, 2010.
  47. Inês Perpetuo; Diana Fernandes; Rita Cascão; et al. "TNF antagonists and tocilizumab have a higher impact on Rheumatoid Arthritis osteoclastogenic stimuli than methotrexate.". Paper presented in XV Congresso Português de Reumatologia, 2010.
  48. Pamela Weinmann; Rita Cascão; et al. "Diminuição da apoptose e da capacidade de activação dos neutrófilos em doentes com poliartrite em fase inicial.". Paper presented in XV Congresso Português de Reumatologia, 2010.
  49. Maria J Santos; Diana Fernandes; F Vinagre; Inês Perpetuo; Rita Cascão; et al. "Does adiponectin have a protective effect in women with rheumatoid arthritis?". Paper presented in 7th International Congress on Autoimmunity, 2010.
  50. Maria J Santos; Diana Fernandes; F. Vinagre; Inês Perpetuo; Rita Cascão; et al. "Higher leptin levels in lupus patients are associated with irreversible damage.". Paper presented in 7th International Congress on Autoimmunity, 2010.
  51. Rita Cascão; et al. "Neutrófilos: Avaliação da Fagocitose num modelo animal de artrite". Paper presented in XV Congresso Português de Reumatologia., 2008.
  52. Rita Cascão; et al. "Functional and molecular study of neutrophils’ role in the initiation and progression of chronic arthritis.". Paper presented in 2nd IMM PhD students’ meeting, 2008.
  53. Pamela Weinmann; Ana C Ferreira; Patricia Pereira; Rita A Moura; Ana F Mourão; Joana Caetano-Lopes; Rita Cascão; et al. "Caracterização da resposta funcional dos neutrófilos em doentes com poliartrite em fase inicial". Paper presented in XV Congresso Português de Reumatologia, 2008.
  54. Ana C Ferreira; Pamela Weinmann; Patricia A Pereira; Rita Cascão; et al. "Characterization of functional response of blood neutrophils from patients with early arthritis.". Paper presented in IMID Workshop, 2008.
  55. Ana C Ferreira; Pamela Weinmann; Rita Cascão; et al. "Effects of corticosteroids on peripheral blood neutrophil transmigration of patients with a polyarthritis of less than 6 weeks duration". Paper presented in 6th International Congress on Autoimmunity, 2008.
  56. Rita Cascão; et al. "T8T and other GJB2 unclassified or controversial sequence variants identified in Portuguese families". Paper presented in ESHG, 2007.
  57. Ana R Rodrigues; et al. "Carrier frequency of GJB2 variants in the Portuguese population". Paper presented in 6th Molecular Biology of Hearing & Deafness Conference, 2007.
  58. Ana Rodrigues; et al. "Spectrum and carrier frequency of GJB2 (Cx26) mutations associated to deafness in Portuguese families". Paper presented in 38º ESHG, 2006.
  59. Cintia Trincão; Ana R. Rodrigues; et al. "CONTRIBUTION OF GJB2 TO HEARING LOSS IN THE PORTUGUESE POPULATION". Paper presented in IEB, 2006.
Journal article
  1. Muyas, Francesc; Rodriguez, Manuel José Gómez; Cascão, Rita; Afonso, Angela; Sauer, Carolin M.; Faria, Claudia C.; Cortés-Ciriano, Isidro; Flores, Ignacio. "The ALT pathway generates telomere fusions that can be detected in the blood of cancer patients". Nature Communications 15 1 (2024): 82. http://dx.doi.org/10.1038/s41467-023-44287-8.
    Published • 10.1038/s41467-023-44287-8
  2. Qin, Nan; Paisana, Eunice; Picard, Daniel; Leprivier, Gabriel; Langini, Maike; Custódia, Carlos; Cascão, Rita; et al. "The long non-coding RNA OTX2-AS1 promotes tumor growth and predicts response to BCL-2 inhibition in medulloblastoma". Journal of Neuro-Oncology 165 2 (2023): 329-342. http://dx.doi.org/10.1007/s11060-023-04508-y.
    Published • 10.1007/s11060-023-04508-y
  3. Domentean, Stefani; Paisana, Eunice; Cascão, Rita; Faria, Claudia C.. Corresponding author: Cascão, Rita. "Role of UBE2C in Brain Cancer Invasion and Dissemination". International Journal of Molecular Sciences 24 21 (2023): 15792. http://dx.doi.org/10.3390/ijms242115792.
    Published • 10.3390/ijms242115792
  4. Roque, Diogo; Cruz, Nuno; Ferreira, Hugo Alexandre; Reis, Catarina Pinto; Matela, Nuno; Herculano-Carvalho, Manuel; Cascão, Rita; Faria, Claudia C.. Corresponding author: Cascão, Rita. "Nanoparticle-Based Treatment in Glioblastoma". Journal of Personalized Medicine 13 9 (2023): 1328. http://dx.doi.org/10.3390/jpm13091328.
    Published • 10.3390/jpm13091328
  5. Paisana, Eunice; Cascão, Rita; Custódia, Carlos; Qin, Nan; Picard, Daniel; Pauck, David; Carvalho, Tânia; et al. "UBE2C promotes leptomeningeal dissemination and is a therapeutic target in brain metastatic disease". Neuro-Oncology Advances 5 1 (2023): http://dx.doi.org/10.1093/noajnl/vdad048.
    Published • 10.1093/noajnl/vdad048
  6. Cruz, Nuno; Herculano-Carvalho, Manuel; Roque, Diogo; Faria, Cláudia C.; Cascão, Rita; Ferreira, Hugo Alexandre; Reis, Catarina Pinto; Matela, Nuno. "Highlighted Advances in Therapies for Difficult-To-Treat Brain Tumours Such as Glioblastoma". Pharmaceutics 15 3 (2023): 928. http://dx.doi.org/10.3390/pharmaceutics15030928.
    Published • 10.3390/pharmaceutics15030928
  7. Blümel, Lena; Qin, Nan; Berlandi, Johannes; Paisana, Eunice; Cascão, Rita; Custódia, Carlos; Pauck, David; et al. "Primary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors". Cell Death & Disease 13 9 (2022): http://dx.doi.org/10.1038/s41419-022-05243-4.
    10.1038/s41419-022-05243-4
  8. Faria, Claudia C.; Cascão, Rita; Custódia, Carlos; Paisana, Eunice; Carvalho, Tânia; Pereira, Pedro; Roque, Rafael; et al. "Patient-derived models of brain metastases recapitulate human disseminated disease". Cell Reports Medicine 3 5 (2022): 100623. http://dx.doi.org/10.1016/j.xcrm.2022.100623.
    Published • 10.1016/j.xcrm.2022.100623
  9. Qin, Nan; Paisana, Eunice; Langini, Maike; Picard, Daniel; Malzkorn, Bastian; Custódia, Carlos; Cascão, Rita; et al. "Intratumoral heterogeneity of MYC drives medulloblastoma metastasis and angiogenesis". Neuro-Oncology (2022): http://dx.doi.org/10.1093/neuonc/noac068.
    Published • 10.1093/neuonc/noac068
  10. Cascão, Rita; Vidal, Bruno; Carvalho, Tânia; Lopes, Inês Pascoal; Romão, Vasco C.; Goncalves, João; Moita, Luis Ferreira; Fonseca, João Eurico. "Celastrol Efficacy by Oral Administration in the Adjuvant-Induced Arthritis Model". Frontiers in Medicine 7 (2020): http://dx.doi.org/10.3389/fmed.2020.00455.
    Published • 10.3389/fmed.2020.00455
  11. Vidal, Bruno; Cascão, Rita; Finnilä, Mikko A J; Lopes, Inês P; da Glória, Vânia G; Saarakkala, Simo; Zioupos, Peter; Canhão, Helena; Fonseca, João Eurico. "Effects of tofacitinib in early arthritis-induced bone loss in an adjuvant-induced arthritis rat model". Rheumatology 58 2 (2018): 371-371. http://dx.doi.org/10.1093/rheumatology/key377.
    Published • 10.1093/rheumatology/key377
  12. Vidal, Bruno; Cascão, Rita; Finnilä, Mikko A. J.; Lopes, Inês P.; Saarakkala, Simo; Zioupos, Peter; Canhão, Helena; Fonseca, João E.. "Early arthritis induces disturbances at bone nanostructural level reflected in decreased tissue hardness in an animal model of arthritis". PLOS ONE 13 1 (2018): e0190920. http://dx.doi.org/10.1371/journal.pone.0190920.
    10.1371/journal.pone.0190920
  13. Cascão, Rita; Vidal, Bruno; Jalmari Finnilä, Mikko Arttu; Lopes, Inês Pascoal; Teixeira, Rui Lourenço; Saarakkala, Simo; Moita, Luis Ferreira; Fonseca, João Eurico. Corresponding author: Cascão, Rita. "Effect of celastrol on bone structure and mechanics in arthritic rats". RMD Open 3 2 (2017): e000438. http://dx.doi.org/10.1136/rmdopen-2017-000438.
    Published • 10.1136/rmdopen-2017-000438
  14. Vidal, Bruno; Cascão, Rita; Finnilä, Mikko A J; Lopes, Inês P; da Glória, Vânia G; Saarakkala, Simo; Zioupos, Peter; Canhão, Helena; Fonseca, João Eurico. "Effects of tofacitinib in early arthritis-induced bone loss in an adjuvant-induced arthritis rat model". Rheumatology 57 8 (2017): 1461-1471. http://dx.doi.org/10.1093/rheumatology/kex258.
    10.1093/rheumatology/kex258
  15. Cascão, Rita; Fonseca, João E.; Moita, Luis F.. "Celastrol: A Spectrum of Treatment Opportunities in Chronic Diseases". Frontiers in Medicine 4 (2017): http://dx.doi.org/10.3389/fmed.2017.00069.
    Published • 10.3389/fmed.2017.00069
  16. Cascão, Rita; Vidal, Bruno; Lopes, Inês P.; Paisana, Eunice; Rino, José; Moita, Luis F.; Fonseca, João E.. Corresponding author: Cascão, Rita. "Decrease of CD68 Synovial Macrophages in Celastrol Treated Arthritic Rats". PLOS ONE 10 12 (2015): e0142448. http://dx.doi.org/10.1371/journal.pone.0142448.
    10.1371/journal.pone.0142448
  17. Vidal, Bruno; Cascão, Rita; Vale, Ana Catarina; Cavaleiro, Inês; Vaz, Maria Fátima; Brito, José Américo Almeida; Canhão, Helena; Fonseca, João Eurico. "Arthritis Induces Early Bone High Turnover, Structural Degradation and Mechanical Weakness". PLOS ONE 10 1 (2015): e0117100. http://dx.doi.org/10.1371/journal.pone.0117100.
    Published • 10.1371/journal.pone.0117100
  18. Cascão, Rita; Vidal, Bruno; Raquel, Helena; Neves-Costa, Ana; Figueiredo, Nuno; Gupta, Vineet; Fonseca, João Eurico; Ferreira Moita, Luis. "Potent Anti-Inflammatory and Antiproliferative Effects of Gambogic Acid in a Rat Model of Antigen-Induced Arthritis". Mediators of Inflammation 2014 (2014): 1-7. http://dx.doi.org/10.1155/2014/195327.
    Published • 10.1155/2014/195327
  19. Vidal, B.; Pinto, A.; Galvão, M.J.; Santos, A.R.; Rodrigues, A.; Cascão, R.; Abdulghani, S.; et al. "Bone histomorphometry revisited". Acta Reumatologica Portuguesa 37 4 (2012): 294-300. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876301488&partnerID=MN8TOARS.
    Published
  20. Cascão, R.; Vidal, B.; Raquel, H.; Neves-Costa, A.; Figueiredo, N.; Gupta, V.; Fonseca, J.E.; Moita, L.F.. "Effective treatment of rat adjuvant-induced arthritis by celastrol". Autoimmunity Reviews 11 12 (2012): 856-862.
    Published • 10.1016/j.autrev.2012.02.022
  21. Cascão, R.; Polido-Pereira, J.; Canhão, H.; Rodrigues, A.M.; Navalho, M.; Raquel, H.; Neves-Costa, A.; et al. "Caspase-1 is active since the early phase of rheumatoid arthritis". Clinical and Experimental Rheumatology 30 1 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84863730477&partnerID=MN8TOARS.
    Published
  22. Moura, R.A.; Cascão, R.; Perpétuo, I.; Canhão, H.; Vieira-sousa, E.; Mourão, A.F.; Rodrigues, A.M.; et al. "Cytokine pattern in very early rheumatoid arthritis favours B-cell activation and survival". Rheumatology 50 2 (2011): 278-282.
    Published • 10.1093/rheumatology/keq338
  23. Mourão, A.; Canhão, H.; Moura, R.A.; Cascão, R.; Weinmann, P.; Rodrigues, A; Polido-Pereira, J.; et al. "Markers of progression to rheumatoid arthritis: Discriminaive value of the new acr/eular rheumatoid arthritis criteria in a portuguese population with early polyarthritis". Acta Reumatologica Portuguesa 36 4 (2011): 370-376. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864757031&partnerID=MN8TOARS.
    Published
  24. Matos, T. D.; Simões-Teixeira, H.; Caria, H.; Cascão, R.; Rosa, H.; O'Neill, A.; Dias, Ó.; et al. "Assessing Noncoding Sequence Variants ofGJB2for Hearing Loss Association". Genetics Research International 2011 (2011): 1-8. http://dx.doi.org/10.4061/2011/827469.
    Published • 10.4061/2011/827469
  25. Caetano-Lopes, J.; Nery, A.M.; Canhão, H.; Duarte, J.; Cascão, R.; Rodrigues, A.; Perpétuo, I.P.; et al. "Chronic arthritis leads to disturbances in the bone collagen network". Arthritis Research and Therapy 12 1 (2010):
    Published • 10.1186/ar2908
  26. Cascão, R.; Moura, R.A.; Perpétuo, I.; Canhão, H.; Vieira-Sousa, E.; Mourão, A.F.; Rodrigues, A.M.; et al. "Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritis". Arthritis Research and Therapy 12 5 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-77958006636&partnerID=MN8TOARS.
    Published • 10.1186/ar3168
  27. Cascão, R.; Rosário, H.S.; Souto-Carneiro, M.M.; Fonseca, J.E.. "Neutrophils in rheumatoid arthritis: More than simple final effectors". Autoimmunity Reviews 9 8 (2010): 531-535.
    Published • 10.1016/j.autrev.2009.12.013
  28. Mourão, A.F.; Canhão, H.; Sousa, E.; Cascão, R.; da Costa, J.B.; de Almeida, L.S.; Oliveira, M.E.; et al. "From a neutrophilic synovial tissue infiltrate to a challenging case of rheumatoid arthritis". Acta Reumatologica Portuguesa 35 2 (2010): 228-231. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650423944&partnerID=MN8TOARS.
    Published
  29. Cascão, C.; Rosário, R.H.; Fonseca, F.J.. "Neutrophils warriors and commanders in immune mediated inflammatory diseases". Acta Reumatologica Portuguesa 34 2 B (2009): 313-326. http://www.scopus.com/inward/record.url?eid=2-s2.0-79551592693&partnerID=MN8TOARS.
    Published
Thesis / Dissertation
  1. Rodrigues, Ana Rita Cascão, 1983-. "Role of IL-1ß in rheumatoid arthritis". PhD, Universidade de Lisboa Faculdade de Medicina, 2012. http://hdl.handle.net/10451/7058.
  2. Cascão, Rita. "Epidemiologia molecular da Surdez Hereditária: Prevalência das variantes patogénicas do gene GJB2 identificadas em famílias Portuguesas". Master, Universidade de Lisboa Faculdade de Ciências, 2007.
  3. Cascão, Rita. "EPIDEMIOLOGIA MOLECULAR DAS MUTAÇÕES NO GENE GJB2 (Cx26) ASSOCIADAS À SURDEZ EM FAMÍLIAS PORTUGUESAS E AVALIAÇÃO DE CORRELAÇÕES GENÓTIPO-FENÓTIPO". Degree, Universidade de Lisboa Faculdade de Ciências, 2006.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/10/26 UBE2C drives leptomeningeal dissemination in brain metastatic disease and is a promising therapeutic target. III ASPIC-ASEICA International Meeting
(Portugal)
2023/05/09 Dissecting the role of CCL2/CCR2 axis in metastatic medulloblastoma XVI CAML PhD Students meeting
(Portugal)
2023/02/03 CCL2/CCR2 pathway as a therapeutic target in the treatment of medulloblastoma XIII APNO
(Portugal)
2023/02/03 PI3K/mTOR inhibition decreases UBE2C-driven leptomeningeal dissemination XIII APNO
(Portugal)
2022/11/15 UBE2C promotes leptomeningeal dissemination and is a therapeutic target in brain metastatic disease 6ª Conferência Anual da redeSAÚDE – Perspetivas Multidisciplinares e Saúde Global na Ulisboa
(Lisbon, Portugal)
2021 Targeting the CCL2-CCR2 axis in metastatic medulloblastoma. XIV CAML IV NeurULisboa PhD Students
2021 Ubiquitin Conjugating Enzymes promote aggressive metastatic brain disease and decrease patients’ survival. 27th Porto Cancer Meeting – Stemness and metastasis: advances in research and clinical translation
2021 Ubiquitin conjugating enzymes promote leptomeningeal dissemination and decrease survival in brain metastatic disease XIV CAML IV NeurULisboa PhD Students
2021 Targeting therapeutic resistance in glioblastoma iMM Postdoc Day
2020/09/25 The role of ubiquitin conjugating enzymes in brain metastases. Cancer Biology: From Basic to Translational Research Webinar - Cancer Biology: From Basic To Translational Research
Liga Portuguesa Contra o Cancro (Lisboa, Portugal)
2019 The role of ubiquitin conjugating enzymes in brain metastases. 35º Congresso Nacional da Sociedade Portuguesa de Neurocirurgia
(lisbon, Portugal)
2018 Patient-derived xenograft models of brain metastases for translational medicine. 3rd International ASPIC meeting
(Lisboa, Portugal)
2016 Modelos animais de metástases cerebrais. IX Neurooncologia
(Porto, Portugal)
2013 Inflammasomes in autoinflammatory diseases Simpósio Inflamação e Dor. Sociedade Portuguesa de Reumatologia.
(Espinho, Portugal)
2012 The role of the inflammasome in the initiation and perpetuation of Rheumatoid Arthritis 10th Medinterna International Meeting “Systemic autoimmune diseases”
(Porto, Portugal)
2012 Drugs that simultaneously down-regulate IL-1ß and TNF secretion significantly reduce inflammation in a rat model of adjuvant-induced arthritis. 8th International Congress on Autoimmunity
(Granada, Spain)
2011 Gambogic acid and Celastrol are two potent anti-inflammatory drugs in a rat model of antigen-induced arthritis. II Simpósio SPR “Artrite e Osso”
(Aveiro, Portugal)
2010 Caracterização do padrão de citocinas nas primeiras 6 semanas de evolução da artrite reumatóide. XV Congresso Português de Reumatologia
(Funchal, Portugal)
2010 Cytokine network in the first 6 weeks of rheumatoid arthritis onset. 7th International Congress on Autoimmunity
(Ljubljana, Slovenia)
2010 Cytokine profile in serum and synovial fluid of established rheumatoid arthritis patients. 7th International Congress on Autoimmunity
(Ljubljana , Slovenia)
2010 TNF Antagonists and tocilizumab have a higher impact on rheumatoid arthritis osteoclastogenic stimuli than methotrexate. 7th International Congress on Autoimmunity
(Ljubljana, Slovenia)
2010 Higher Leptin levels in lupus patients are associated with irreversible damage. 7th International Congress on Autoimmunity
(Ljubljana, Slovenia)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2024 - Current Exploiting UBE2C as a new prognostic marker and therapeutic target in brain metastases
Co-supervisor
 PhD (PhD)
Instituto de Medicina Molecular, Portugal
2023 - Current Exploiting UBE2C as a prognostic marker and therapeutic target in human brain metastases
Co-supervisor
2023 - 2024 Identification and validation of molecular targets involved in glioblastoma recurrence
Co-supervisor
 Master (Master)
Instituto de Medicina Molecular, Portugal
2022 - 2023 Targeting therapeutic resistance in glioblastoma
Co-supervisor
2021 - 2022 Validação clínica de marcadores de resistência à terapêutica no glioblastoma - Clínica Universitária de Neurocirurgia.
Co-supervisor
 undergraduate medical student (Other)
Universidade de Lisboa Faculdade de Medicina, Portugal
2021 - 2022 The role of UBE2C in the outcome of cancer patients with brain metastases - Clínica Universitária de Neurocirurgia
Co-supervisor
 GAPIC project. Funding agency: 3.ª Bolsa iMM João Lobo Antunes/FMUL (Other)
Universidade de Lisboa Faculdade de Medicina, Portugal
2018 - 2022 Targeting the CCL2-CCR2 signalling pathway in metastatic medulloblastoma
Co-supervisor
 Bolsa de Doutoramento FCT (PhD)
Universidade de Lisboa Faculdade de Medicina, Portugal
2020 - 2021 Avaliação do papel do eixo CCL2/CCR2 na disseminação do meduloblastoma
Co-supervisor
 Co-tutor of Master thesis (MD students) (Master)
Universidade de Lisboa Faculdade de Medicina, Portugal
2020 - 2021 Clinical validation of molecular targets involved in glioblastoma recurrence
Co-supervisor
 24.º Programa Educação pela Ciência | Bolsas CHLN/FMUL (n.º 20210029) (Other)
Universidade de Lisboa Faculdade de Medicina, Portugal
2017 - 2021 Identification and validation of genetic markers of brain metastases
Co-supervisor
 Lisbon BioMed PhD Program (PhD)
Universidade de Lisboa Faculdade de Medicina, Portugal
2016 - 2018 Effect of celastrol in leukocytes from rheumatoid arthritis patients
Supervisor
 Ciências Biofarmacêuticas (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015 - 2016 Efficacy and toxicity evaluation of celastrol in adjuvant-induced arthritis rat model
Supervisor
 Genética Molecular e Biomedicina (Master)
Universidade Nova de Lisboa, Portugal
2015 - 2016 Preclinical development of a new compound for the treatment of arthritis
Supervisor
 Biologia Molecular e Genética (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal
2014 - 2015 Evaluation of a new compound for the treatment of arthritis in the AIA rat model
Supervisor
 Biologia Molecular e Genética (Master)
Universidade de Lisboa Faculdade de Ciências, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/10/19 - 2023/10/20 iMM PostDoc Day (2023/10/19 - 2023/10/20)
Meeting (Co-organisor)
 Instituto de Medicina Molecular, Portugal
2022/10/14 - 2022/10/14 iMM PostDoc Day (2022/10/14)
Workshop (Co-organisor)
 Instituto de Medicina Molecular, Portugal
2018/02/25 - 2018/02/25 iMM PostDoc Day (2018/02/25 - 2018/02/25)
Workshop (Co-organisor)
 Instituto de Medicina Molecular, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2014 - Current Participation in Corrida Saúde Mais Solidária, organized by the students of the Medical School (AEFML), to create awareness and to fundraise for brain tumor research, through the Brain Tumor Team, BTT. The BTT has gathered more than 500 participants, including health care professionals, scientists, patients and their families. The team participates in Corrida Saúde Mais Solidária since May 2014.
Other
 Corrida Saúde + Solidária - Associação de Estudantes da Faculdade de Medicina de Lisboa, Portugal
2023 - 2023 Participation in Noite Europeia dos Investigadores (NEI), Researchers in Action for Inclusion in Science and Education (RAISE).
Other
 Noite Europeia dos Investigadores (NEI)
Instituto de Medicina Molecular, Portugal
2022 - 2022 Participation in Noite Europeia dos Investigadores (NEI), Researchers in Action for Inclusion in Science and Education (RAISE).
Other
 Noite Europeia dos Investigadores (NEI)
Instituto de Medicina Molecular, Portugal
2004/09/01 - 2005/07/31 Team management and Project management courses organized by GESP-UNIVA da Fundação da Faculdade de Ciências da Universidade de Lisboa
Workshop
 Team management and Project management courses
Universidade de Lisboa Faculdade de Ciências, Portugal
1997 - 1998 Voluntary work at Reserva Natural do Paúl do Boquilobo
Other

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023 Epithelial to mesenchymal transition pathway in pituitary endocrine tumors
(Thesis) Main arguer
 Fábio Domingues Carril Reis (Master)
Universidade Nova de Lisboa, Portugal
2021 Screening of new and old drugs to prevent breast cancer brain metastasis
(Thesis) Main arguer
 Margarida Dionísio Lopes (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2020 Blood-brain barrier: role in brain metastasization of breast cancer
(Thesis) Main arguer
 Ana Rita da Costa Garcia (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Association member

Society Organization name Role
2023/12/20 - Current European Society For Medical Oncology (ESMO) Member
2022 - Current Postdoctoral Association of Instituto de Medicina Molecular João Lobo Antunes Member/Representative of the Postdoctoral Association from Instituto de Medicina Molecular João Lobo Antunes (iMM)
2017 - Current European Association for Cancer Research (EACR)
2017 - Current Associação Portuguesa de Investigação em Cancro (ASPIC)
2017 - 2018 Postdoctoral Association of Instituto de Medicina Molecular João Lobo Antunes Member/Representative of the Postdoctoral Association from Instituto de Medicina Molecular (iMM)

Consulting

Activity description Institution / Organization
2006 - 2007 Scientific, technical and commercial consultant at Biosurfit, S.A.

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2019 - 2019 Course: Pathophysiological mechanisms of rheumatic diseases. Mecanismos fisiopatológicos das doenças reumática. (Mestrado integrado) Universidade de Lisboa Faculdade de Medicina, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2021 - 2024 Scientific Adviser in a PhD student Thesis Committee. Student: Rita Garcia. Title "Unravelling and modulating the interplay between breast cancer cells and blood-brain barrier endothelial cells: a new hope to prevent brain metastasis formation" Universidade de Lisboa Faculdade de Farmácia, Portugal
2013 - 2016 Scientific Adviser in a PhD student Thesis Committee. Thesis entitled "Nano inflammation: How inflammation early affects bone properties at the onset of rheumatoid arthritis.". Student: Bruno Vidal
Member
 Universidade de Lisboa Faculdade de Medicina, Portugal Fundação para a Ciência e a Tecnologia

Mentoring / Tutoring

Topic Student name
2014 - 2015 Evaluation of a new compound for the treatment of arthritis in vivo Eunice Paisana
2011 - 2011 Immunology/Rheumatology Ana Sofia Diogo

Other jury / evaluation

Activity description Institution / Organization
2023 - Current Evaluator of Scientific Projects, Programa Educação pela Ciência/FMUL, GABINETE DE APOIO À INVESTIGAÇÃO CIENTÍFICA, TECNOLÓGICA E INOVAÇÃO (GAPIC), Faculdade de Medicina da Universidade de Lisboa Universidade de Lisboa, Portugal
2022 - Current Reviewer for Frontiers in Pharmacology.
2018 - 2018 Reviewer for Pharmaceutical Biology journal.
2016 - 2016 Reviewer for Pathogens and Disease journal.
2015 - 2015 Reviewer for The Journal of Rheumatology.
2012 - 2015 Reviewer for PLoS ONE journal.
2013 - 2013 Reviewer for Clinical & Experimental Immunology journal.
2013 - 2013 Reviewer for Arthritis journal.
2012 - 2013 Reviewer for Acta Rheumatologica Portuguesa journal.
Distinctions

Award

2022 Lídia Silva Santos Postdoctoral Achievement Award
Instituto de Medicina Molecular, Portugal
2018 Best poster prize. Title: Patient-derived xenografts of brain metastases: a tool for translational medicine. II EuroPDX Workshop. Weggis, Switzerland
2009 Pfizer Research Grant
Pfizer Portugal, Portugal
2007 Fundo de apoio à comunidade científica (FACC) from FCT
Fundação para a Ciência e a Tecnologia, Portugal