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Ana Gabriela Henriques (AGH) completed her PhD in Biochemistry (Neurochemistry/Neurobiology) in 2009 by the University of Aveiro (UA), in the Alzheimer's disease (AD) field. From April 2019 to May 2020 AGH had a contract as Assistant Researcher at the Institute of Biomedicine (iBiMED), DCM, a position awarded in a competitive FCT call for researchers (CEEC2017). In June 2020, AGH started her position as Assistant Professor at Medical Sciences Department (DCM), University of Aveiro, and she is currently a member of the Ethics Council UA . She also developed teaching activities from 2009-2019, as Invited Assistant Professor at the same department. AGH was funded in 2019 by the American Alzheimer´s Association research grant program, to run as PI the EXO_DIAG_AD project. During her scientific career she participated in more than 10 research projects, being WP leader in 2 of them (AD-Blood and pAGE). Her research work resulted in more than 40 published papers in international peer-reviewed journals and 3 book chapters (h-index= 20; >1250 citations). AGH is currently the coordinator of the Clinical Research Laboratory and of the Biobank at iBiMED. Her research activities focus on AD field, the most common neurodegenerative disorder among elderly. At the fundamental research level AGH team dig into the role of extracellular vesicles (EVs) and their involvement in AD disease pathogenesis. In a translational and clinical perspective, AGH team explores the potential of blood-derived EVs in clinical biomarker discovery for AD differential diagnosis and/or therapeutic interventions.
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Identification

Personal identification

Full name
Ana Gabriela Henriques

Citation names

  • Henriques, Ana Gabriela
  • Henriques, AG

Author identifiers

Ciência ID
B318-063D-E080
ORCID iD
0000-0003-0851-6979
Google Scholar ID
https://scholar.google.pt/citations?user=Meo31pkAAAAJ
Researcher Id
F-8414-2011
Scopus Author Id
7102209466

Websites

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Neurosciences
  • Medical and Health Sciences - Basic Medicine - Human Genetics
  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Biochemistry

Languages

Language Speaking Reading Writing Listening Peer-review
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Education
Degree Classification
2009/03/18
Concluded
 Biochemistry (Doutoramento)
Major in (Neurochemistry/Neurobiology)
Universidade de Aveiro, Portugal
"A Biologia do Aß e a Sua Contribuição para a Doença de Alzheimer" (THESIS/DISSERTATION)
 Aproved
2003/06/26
Concluded
 Molecular Microbiology (Mestrado)
Major in Não Aplicável
Universidade de Aveiro, Portugal
2000/08/01
Concluded
 Biology (Licenciatura)
Major in Não Aplicável
Universidade de Aveiro Departamento de Biologia, Portugal
Affiliation

Science

Category
Host institution 		Employer
2015/08 - Current Principal Investigator (Research) Universidade de Aveiro Instituto de Biomedicina, Portugal
Universidade de Aveiro Instituto de Biomedicina, Portugal
2019/04/01 - 2020/05/31 Auxiliary Researcher (Research) Fundação para a Ciência e a Tecnologia, Portugal
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2009/04 - 2012/04 Postdoc (Research) Universidade de Aveiro Departamento de Biologia, Portugal
Universidade de Aveiro Departamento de Biologia, Portugal
2003/05 - 2004/08 Contracted Researcher (Research) Universidade de Aveiro Departamento de Biologia, Portugal
2001/06 - 2003/05 Contracted Researcher (Research) Universidade de Aveiro Departamento de Biologia, Portugal
2000/09 - 2001/05 Research Trainee (Research) Universidade de Aveiro Departamento de Biologia, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2020/06/01 - Current Assistant Professor (University Teacher) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2015/10/13 - 2019/03/31 Invited Assistant Professor (University Teacher) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2011/10/13 - 2015/10/12 Invited Assistant Professor (University Teacher) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2009/10/13 - 2010/10/12 Invited Assistant Professor (University Teacher) Universidade de Aveiro, Portugal

Positions / Appointments

Category
Host institution 		Employer
2023/07 - Current Member of the DCM Council for Pedagogical Quality and Assessment Universidade de Aveiro Departamento de Ciências Médicas, Portugal
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2022/02/09 - Current Member of the Ethics Council UA Universidade de Aveiro, Portugal
Universidade de Aveiro, Portugal
2018/10 - Current President of Ethics Committee at DCM Universidade de Aveiro Departamento de Ciências Médicas, Portugal
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017/06 - Current Coordinator of the Clinical Research Laboratory at iBiMED Universidade de Aveiro Instituto de Biomedicina, Portugal
2015/10 - Current Coordinator of the Biobank installed at iBiMED Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2015/01 - Current Member of the Scientific Council of the Institute of Biomedicine (iBiMED) Universidade de Aveiro Instituto de Biomedicina, Portugal
2009 - Current Co-coordinator of the External Quality Control Program: Alzheimer´s Association Quality Control Program for CSF biomarkers Universidade de Aveiro, Portugal
2023/09 - 2024/02 Co-coordinator of the 2nd Edition of the Graduate Specialisation Programme in Leadership and Management in Health Universidade de Aveiro Departamento de Ciências Médicas, Portugal
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2023/02 - 2023/07 Co-coordinator of the 1st Edition of the Graduate Specialisation Programme in Leadership and Management in Health Universidade de Aveiro Departamento de Ciências Médicas, Portugal
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017/11 - 2022 Council Member of the Department of Medical Sciences (DCM) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017/02 - 2018/10 Vice-President of the Subcommittee on Pre-Clinical Research Universidade de Aveiro Departamento de Ciências Médicas, Portugal
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2012/02 - 2018/10 Vice-Director of the Master in Molecular Biomedicine Universidade de Aveiro Departamento de Ciências Médicas, Portugal
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2012 - 2014 Coordinator of the Clinical Research Laboratory at Center for Cell Biology Universidade de Aveiro Departamento de Biologia, Portugal
2010 - 2014 Member of the Scientific Council of the Center for Cell biology (CBC) Universidade de Aveiro Departamento de Biologia, Portugal

Others

Category
Host institution 		Employer
2004/10 - 2009/03 PhD Fellow (FCT SFRH/BD/16071/2004) Universidade de Aveiro Departamento de Biologia, Portugal
Projects

Grant

Designation Funders
2012/06 - 2015/05 BIOMARKAPDua - Biomarkers for Alzheimer's disease and Parkinson's disease, University of Aveiro.
Provided by PTCRIS: 123874
Post-doc
Fundação para a Ciência e a Tecnologia
2003 - 2006 Abeta complex formation: role in Abeta aggregation or clearance
POCTI/NSE/40682/2001
Research Fellow
Concluded
2001 - 2004 Stress and Alzheimer´s disease: a molecular cellular approach
POCTI/33520/99
Research Fellow
Universidade de Aveiro Departamento de Biologia, Portugal
Concluded

Contract

Designation Funders
2020 - 2024 Principal Investigator at iBiMED - Biomarker Discovery Group
UIDB/04501/2020
UIDP/04501/2020
Principal investigator
Fundação para a Ciência e a Tecnologia
2019/01 - 2023/10/31 Exosomes as Diagnostic Tools for Alzheimer´s disease - EXO_DIAG_AD
2263
Principal investigator
Alzheimer's Association
2022 - 2023 ADpro - Proof of concept for Alzheimer's disease blood biomarkers
CENTRO-01-0145-FEDER-181255
Researcher
Universidade de Aveiro Instituto de Biomedicina, Portugal
Concluded
2017/02 - 2020/01 Synaptic networks and Personalized Medicine Approaches to Understand Neurobehavioural Diseases Across the Lifespan
SAICTPAC/0010/2015
Researcher
Universidade de Aveiro Instituto de Biomedicina, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2017 - 2020 Protein aggregation across lifespan- pAGE
Centro-01-0145-FEDER-000003
Researcher
Universidade de Aveiro Instituto de Biomedicina, Portugal
Concluded
2016/07/01 - 2019/12/30 AD-Blood assay - Blood based early and predictive diagnostics of Alzheimer's dementia
PTDC/DTP-PIC/5587/2014
Researcher
Universidade de Aveiro Instituto de Biomedicina, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2015 - 2018 Principal Investigator at iBiMED - Biomarker Discovery Group
UID/BIM/04501/2013
UID/BIM/04501/2019
Principal investigator
Fundação para a Ciência e a Tecnologia
Concluded
2013/05 - 2015/09 When sperm forget
Provided by PTCRIS: 124922
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
2013 - 2015 'JPND, BIOMARKAPD - Biomarkers for Alzheimer's disease and Parkinson's disease
BIOMARKAPD
Researcher
Universidade de Aveiro Departamento de Biologia, Portugal
Concluded
2011/02 - 2014/07 Deciphering neurotrophic signaling pathways mediated by the Alzheimer's Amyloid Precursor Protein, APP
Provided by PTCRIS: 111980
Researcher
Universidade de Aveiro, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010/05 - 2013/09 Abeta mediated biochemical responses underlying senile plaque and neurofibrillary tangle histopathology in Alzheimer's disease
Provided by PTCRIS: 101317
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
2007 - 2010 cNEUPRO-Clinical Neuroproteomics of Neurodegenerative Diseases
LSHM-CT-2007-037950 - FP6-LIFESCIHEALTH
Researcher
Concluded
2004 - 2006 APOPIS-Abnormal proteins in the pathogenesis of neurodegenerative disorder
EU Project PL503330, - FP6-LIFESCIHEALTH
Researcher
Universidade de Aveiro Departamento de Biologia, Portugal
Concluded
2001 - 2004 DIADEM-Early Diagnosis of Alzheimer's Disease and Related Dementia
EU Project QLRT-2000-02362, - FP5-LIFE QUALITY
Researcher
Universidade de Aveiro Departamento de Biologia, Portugal
Concluded
Outputs

Publications

Book chapter
  1. Soure, I.; Branco, H.; Sobrinho Simõoes, M.A.; Henriques, Ana Gabriela; Vasconcelos, M.H.; Xavier, C.P.R.. "The role of extracellular vesicles in the intercellular transfer of cancer hallmarks and drug resistance traits". In Advances in Cancer Research. Academic Reads, 2022.
    Published
  2. Teixeira, M.; Soares Martins, T.; Gouveia, M.; Henriques, Ana Gabriela; Santos, M.; Ribeiro, F.. "Effects of Exercise on Circulating Extracellular Vesicles in Cardiovascular Disease". Springer - Nature, 2021.
    Published
  3. Machado, J.; Henriques, Ana Gabriela. "Sinalização celular como alvo para terapia de doenças". In O Essencial em...Sinalização Celular. Portugal: Edições Afrontamento, 2012.
    Published
Conference abstract
  1. Vaz, M.; Soares Martins, T.; da Cruz e Silva, O.A.B.; Nunes, A.; Henriques, Ana Gabriela. "FTIR analysis of neuronal-like cells upon Abeta exposure - Conference abstract published in Alzheimer's and dementia". Paper presented in Alzheimer's Association International Conference - AAIC 2023, 2023.
    Published
  2. Soares Martins, T.; Rosa, I.M.; da Cruz e Silva, O.A.B.; Henriques, A.G.. "Blood-derived extracellular vesicles phosphoproteome as a resource of biomarker candidates for Alzheimer's disease - Conference abstract published in Alzheimer's and dementia". Paper presented in Alzheimer's Association International Conference - AAIC 2023, 2023.
    Published
  3. Gouveia, M.; Soares Martins, T.; Schmidt, C.; Gois, P.; Teixeira, M.; Munoz, X.; Ximenez-Embun, P.; et al. "Exercise training improves the exosomal content in patients with heart failure". Paper presented in American College of Cardiology, Washington, 2022.
    Published
  4. Soares Martins, T.; Rosa, I.M.; da Cruz e Silva, O. A. B.; Henriques, A.G.. "Exosomal levels of soluble amyloid precursor fragments in aging and dementia - Conference abstract published in Alzheimer's and dementia". Paper presented in Alzheimer's Association International Conference - AAIC 2021, 2021.
    Published • https://doi.org/10.1002/alz.057795
  5. Ferreira, M.; Soares Martins, T.; da Cruz e Silva, O.A.B.; Vitorino, R.; Henriques, A.G.. "Bioinformatic analysis of senile plaques and neurofibrillary tangles proteomes - Conference abstract published in Alzheimer's and dementia". Paper presented in Alzheimer's Association International Conference - AAIC 2021, 2021.
    Published • https://doi.org/10.1002/alz.057796
  6. Soares Martins, T; da Cruz e Silva, O.A.B.; Henriques, A.G.. "Peripheral exosomal biomarker candidates for Alzheimer's disease identified by bioinformatic analysis. Conference abstract published in Alzheimer's and dementia". Paper presented in AAIC Neuroscience Next, 2020.
    Published • https://doi.org/10.1002/alz.12278
  7. Henriques, Ana Gabriela; Soares Martins, T.; Magalhães, S.; Rosa, I.M.; da Cruz e Silva, O.A.B.; Nunes, A.. "Lipid profiles of extracellular vesicles are distinct for Alzheimer's disease cases. Conference abstract published in Alzheimer's and dementia". Paper presented in Alzheimer's Association International Conference, 2020.
    Published • 10.1002/alz.043980
  8. Soares Martins, T.; Marçalo, R.; da Cruz e Silva, C.B.; Melo, T.; Trindade, D.; Rosa, I.M.; Amado, F.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela. "Proteomic analysis of exosomes isolated using precipitation and column-based approaches. Conference abstract published in JEV". Paper presented in ISEV2020, 2020.
    Published • 10.1080/20013078.2020.1784511
  9. Soares Martins, T.; Catita, J.; Rosa, I.M.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela. "Comparative analyses of exosome isolation methods from distinct biofluids. Conference abstract published in JEV". Paper presented in ISEV2018, Barcelona, 2018.
    Published • 10.1080/20013078.2018.1461450
  10. Henriques, Ana Gabriela; Crespo-López, Elena; da Cruz e Silva, Edgar F.; da Cruz e Silva, Odete A.B.. "Abeta effects on APP metabolism". 2006.
    10.1016/j.jalz.2006.05.777
  11. Henriques, AG; Santos, SCT; Silva, EFD; Silva, OABD. "Neurotoxic effects of sodium azide lead to alterations in amyloid precursor protein metabolism and protein phosphatase 1 expression.". 2004.
    Published
  12. Henriques, Ana Gabriela S.; Santos, Sara; Rebelo, Sandra; Vieira, Sandra; da Cruz e Silva, Edgar F.; da Cruz e Silva, Odete A.B.. "Isoform specific responses of the Alzheimer's amyloid precursor protein". 2004.
    Published • 10.1016/s0197-4580(04)80127-1
Conference poster
  1. Soares Martins, T.; Pelech, S.; Ferreira, M.; Pinho, B.; Breitling, B.; Hansen, N.; Esselmann, H.; et al. "Blood-derived extracellular vesicles proteome and phosphoproteome profiling in Alzheimer's disease through microarray analysis". Paper presented in AD/PD 2024, 2024.
  2. Vaz, M.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela. "Extracellular Vesicles biogenesis and release are affected by abeta peptide". Paper presented in AD/PD 2024, 2024.
  3. Soares Martins, T.; Rosa, I.M.; da Cruz e Silva, O. A. B.; Henriques, Ana Gabriela. "Blood-derived extracellular vesicles phosphoproteome as a resource of biomarker candidates for AD". Paper presented in Alzheimer's Association International Conference - AAIC 2023, 2023.
  4. Vaz, M.; Soares Martins, T.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela. "FTIR analysis of neuronal-like cells upon Abeta exposure". Paper presented in Alzheimer's Association International Conference - AAIC 2023, 2023.
  5. Vaz, M.; Soares Martins, T.; da Cruz e Silva, O.A.B; Henriques, Ana Gabriela. "Abeta effect in extracellular vesicles biogenesis and secretion". Paper presented in 2nd Meeting of the Portuguese Network on Extracellular Vesicles, 2023.
  6. Soares Martins, T.; Rosa, I.M.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela. "Analysis of blood-derived extracellular vesicles phosphoproteome reveals new biomarker candidates for AD diagnosis". Paper presented in Workshop on Novel Diagnostic Tools for Alzheimer’s disease, 2023.
  7. Soares Martins, T.; Pinho, B.; Trindade, D.; Vaz, M.; Henriques, Ana Gabriela. "Exosomes signatures with putative diagnostic value for Alzheimer's disease". Paper presented in Workshop on Novel Diagnostic Tools for Alzheimer’s disease, 2023.
  8. Vaz, M.; Soares Martins, T.; da Cruz e Silva, O.A.B.; Henriques, A.G.. "Biogenesis and secretion of extracelular vesicles upon Abeta treatment". Paper presented in Workshop on Novel Diagnostic Tools for Alzheimer’s disease, 2023.
  9. Alves, Steven R.; de Almeida, Maria Soares Cachide; da Cruz e Silva, Cristóvão; Ilka M. Rosa; Henriques, Ana Gabriela; Odete A. B. da Cruz e Silva. Corresponding author: Odete A. B. da Cruz e Silva. "Insulin signalling and insulin resistance in Alzheimer¿s disease.". Paper presented in ADPD 2023 - International Conference on Alzheimer's and Parkinson's Diseases and related neurological disorders, 2023.
  10. Vaz, M.; Soares Martins, T.; da Cruz e Silva, O.A.B; Nunes, A.; Henriques, Ana Gabriela. "Abeta effect on neuronal-like cells metabolic profile". Paper presented in AD/PD 2023, 2023.
  11. Soares Martins, T.; Ferreira, M.; Magalhães, S.; Vogelgsang, J.; Breitling, B.; Hansen, N.; Esselmann, H.; et al. "Metabolic profile of extracellular vesicles in Alzheimer's disease.". Paper presented in 2nd Symposium on Alzheimer’s Disease: An Update on Pathology and Therapeutics, 2023.
  12. Trindade, Dário; Almeida, Maria; Guedes, Sandra; Rosa, Ilka; da Cruz e Silva, Odete; Henriques, Ana Gabriela. "Clusterin association with dementia in a primary care-based cohort". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  13. Soares Martins, T.; Rosa, I.M.; da Cruz e Silva, O.A.B.; Henriques, A.G.. "Exosomal levels of soluble amyloid precursor fragments in aging and dementia". Paper presented in Alzheimer's Association International Conference - AAIC 2021, 2021.
  14. Ferreira, M.; Soares Martins, T.; da Cruz e Silva, O.A.B.; Vitorino, R.; Henriques, A.G.. "Bioinformatic analysis of senile plaques and neurofibrillary tangles proteomes". Paper presented in Alzheimer's Association International Conference - AAIC 2021, 2021.
  15. Soares Martins, T.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela. "Peripheral exosomal biomarker candidates for Alzheimer's disease identified by bioinformatic analysis". Paper presented in AAIC Neuroscience Next, 2020.
  16. Soares Martins, T.; Magalhães, S.; Rosa, I.M.; da Cruz e Silva, O.A.B.; Nunes, A.; Henriques, Ana Gabriela. "Lipid profiles of extracellular vesicles are distinct forAlzheimer's disease cases". Paper presented in Alzheimer's Association International Conference, 2020.
  17. Soares Martins, T.; Marçalo, R.; da Cruz e Silva, C.B.; Melo, T.; Trindade, D.; Rosa, I.M.; Amado, F.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela. "Proteomic analysis of exosomes isolated using precipitation and column based approaches". Paper presented in ISEV2020, 2020.
  18. Soares Martins, T; Magalhães, S; Rosa, I.M.; Vogelgsang, J.; Wiltfang, J.; Delgadillo, I.; Catita, J.; et al. "Fourier Transformed Infrared Spectroscopy of Extracellular Vesicles as a Diagnostic Tool for Alzheimer's". Paper presented in GEIVEX, 2019.
  19. Vaz, M.; Trindade, D.; Domingues, C.; Da Cruz E Silva, O.A.B.; Henriques, Ana Gabriela. "IL-8 and MCP-1 impact on kinases and phosphatases involved in Tau phosphorylation". Paper presented in 10th Meeting on Signal Transduction, 2019.
  20. Oliveira, J.M.; Soares Martins, T.; da Cruz E Silva, C. B.; Müller, T.; Cova, M.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela. "Neuronal phosphoproteome targets responsive to phosphatase inhibition". Paper presented in 10th Meeting on Signal Transduction, 2019.
  21. Reis, J.; Rodrigues, M.; Soares, E.; Ferreira, H.; Pita, I; Viana, S.D.; Lemos, C.; et al. "Emotional, neurochemical and extracellular vesicles signature of aerobic physical exercise". Paper presented in Ageing: models, mechanisms and therapies, 2019.
  22. Soares Martins, T.; Magalhães, S.; Rosa, I.M.; Vogelgsang, J.; Wiltfang, J.; da Cruz e Silva, O.A.B.; Nunes, A.; Henriques, Ana Gabriela. "FTIR spectral analysis of serum samples from Alzheimer's disease cases: a pilot study". Paper presented in V iBiMED Post-Graduation Symposium, 2019.
  23. Magalhães, S.; Trindade, D.; Soares Martins, T.; Rosa, I.M.; Delgadillo, I.; Goodfellow, J.B.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela. "FTIR spectroscopy reveals changes in protein aggregation profile in plasma from middle to old age". Paper presented in V iBiMED Post-Graduation Symposium, 2019.
  24. Almeida, I.; Magalhães, S.; Soares Martins, T.; Rosa, I.M.; Delgadillo, I.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela; Nunes, A.. "ATR-FTIR spectroscopy detects changes in lipid profile during aging". Paper presented in V iBiMED Post-Graduation Symposium, 2019.
  25. Magalhães, S.; Trindade, D.; Soares Martins, T.; Rosa, I.M.; Delgadillo, I.; Goodfellow, B.J.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela; Nunes, A.. "Monitoring plasma protein aggregation during ageing using FTIR spectroscopy". Paper presented in Jornadas do CICECO 2019, 2019.
  26. Soares Martins, T.; Marçalo, R.; Trindade, D.; Rosa, I.M.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela. "Blood-derived exosomal biomarkers for Alzheimer's disease". Paper presented in 14th International Conference on Alzheimer's & Parkinson¿s Diseases, 2019.
  27. Magalhães, S.; Trindade, D.; Soares Martins, T.; Rosa, I.M.; Delgadillo, I.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela; Nunes, A.. "Age-related protein aggregation in human plasma". Paper presented in Strategies and tools for modulating pathologic protein self-assembly, 2019.
  28. Cachide, M.; Rosa, I.M.; Carvalho, L.; da Cruz e Silva, O.A.B; Henriques, Ana Gabriela. "ApoE and Bin-1 genetic studies in a primary care-based cohort". Paper presented in IV Post-Graduate Symposium on Biomedicine, 2018.
  29. Trindade, D.; Soares Martins, T.; Rosa, I.M.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela. "Clinical Assessment of protein Agregation Across Human Lifespan". Paper presented in IV Post-Graduate Symposium on Biomedicine, 2018.
  30. Magalhães, S.; Soares Martins, T.; Rosa, I.M.; Henriques, Ana Gabriela; da Cruz e Silva, O. A. B.; Delgadillo, I.; Goodfellow, B.J.; Nunes, A.. "Unravelling an age-related metabolomic profile of human plasma: a spectroscopic approach (preliminary data)". Paper presented in IV Post-Graduate Symposium on Biomedicine, 2018.
  31. Cachide, M.; Rosa, I.M.; Carvalho, L.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela. "Alzheimer risk loci in a dementia subgroup of a primary care-based portuguese cohort". Paper presented in Encontro Ciência 2018, 2018.
  32. Magalhães, S.; Soares Martins, T.; Rosa, I.M.; Henriques, Ana Gabriela; da Cruz e Silva, O. A. B.; Delgadillo, I.; Goodfellow, B.J.; Nunes, A.. "ATR-FTIR spectroscopy detects age-related changes in human plasma: preliminary data". Paper presented in Encontro Ciência 2018, 2018.
  33. Henriques, Ana Gabriela; Rebelo, S.; Blennow, K.; Zetterberg, H.; da Cruz e Silva, O.A.B.. "Participation of the Neuroscience and Signalling Laboratory from Aveiro in The Alzheimer´s Association QC Program". Paper presented in 2nd meeting of the CSF society, 2018.
  34. Soares Martins, T.; Rosa, I.M.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela. "Exosome Isolation from different biofluids using precipitation-based and column-based methods.". Paper presented in III Post-Graduate Symposium on Biomedicine, 2017.
  35. Oliveira, J.; Soares Martins, T.; da Cruz E Silva, C. B.; Müller, T.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela. "Phosphoprotein profiles triggered by OA involved in neuronal death and cytoskeletal organization". Paper presented in XV meeting SPN 2017, 2017.
  36. Cachide, M.; Rosa, I.M.; Carvalho, L.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela. "Genetic risk factors in a dementia subgroup of a primary care-based portuguese cohort". Paper presented in XV meeting SPN 2017, 2017.
  37. Nadais, A.; Santos, J.; Jesus, J.; Henriques, Ana Gabriela; da Cruz e Silva, O.A.B.. "Protein aggregation and phosphorylation in a dementia subgroup of a primary care-based cohort". Paper presented in XV meeting SPN 2017, 2017.
  38. Costa, M.; Alves, S.; Rebelo, S.; Henriques, Ana Gabriela; da Cruz e Silva, O.A.B.. "Structural functional relationships of the Alzheimer’s Amyloid Precursor Protein". Paper presented in XV meeting SPN 2017, 2017.
  39. Rosa, I.M.; Henriques, Ana Gabriela; da Cruz e Silva, O.A.B.. "Caracterização de Pacientes Hipertensos no Coorte dos Cuidados de Saúde Primária na Região de Aveiro". Paper presented in 11º Congresso Português de Hipertensão e Risco Cardiovascular, 2017.
  40. Lopes, J; Correia, M; Silva, R.; Rosa, I.M.; Henriques, Ana Gabriela; Delgadillo, I.; da Cruz e Silva, O.A.B.; Nunes, A.. "Identification of metabolic changes in dementia patients using FTIR". Paper presented in 1st International Electronic Conference on Metabolomics, 2016.
  41. Oliveira, J.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela. "Aß Effects on Stathmin in Rat Primary Cortical Neurons". Paper presented in 50th Meeting of SPMicros - Microscopy and Microanalysis in Materials and Life Sciences, 2016.
  42. de Oliveira, Joana Machado; Henriques, Ana Gabriela; Martins, Filipa; Rebelo, Sandra; da Cruz e Silva, Odete A. B.. "Abeta role in APP and Tau phosphorylation: relevance to Alzheimer´s disease". Paper presented in Research Day UA 2014, 2014.
  43. Oliveira, J.; Henriques, Ana Gabriela; Martins, F.; Rebelo, S.; da Cruz e Silva, O.A.B.. "APP Thr668 phosphorylation correlates with Abeta exposure". Paper presented in SINAL 2013, 7th National Meeting on Cell Signaling, 2013.
  44. Silva, R.C.; Henriques, Ana Gabriela; Oliveira, J.; Carvalho, L.; Rosa, I.M.; Delgadillo, I.; da Cruz e Silva, O.A.B.; Nunes, A.. "Identificação de biomarcadores de Alzheimer por FTIR – estudo piloto". Paper presented in VI National Congress Brain Aging and Alzheimer's Disease, 2013.
  45. Rosa, I.M.; Henriques, Ana Gabriela; Cova, M.; Fernandes, E.F.; Marote, A.; Afreixo, V.; da Cruz e Silva, O.A.B.. "Cognitive Evaluation in Primary Care of the Aveiro Cohort". Paper presented in 3rd Research day@UA, 2013.
  46. Henriques, Ana Gabriela; Oliveira, J.; Gomes, B.; Ruivo, R.; da Cruz e Silva, E.F.; da Cruz e Silva, O.A.B.. "In primary neuronal cultures Abeta disaggregating proteins reduce the abnormal accumulation of intracellular sAPP". Paper presented in XIII Reunião da Sociedade Portuguesa de Neurociências, 2013.
  47. Oliveira, J.M.; Henriques, Ana Gabriela; Martins, F.; Rebelo, S.; da Cruz e Silva, O.A.B.. "Abnormal phosphorylation of APP-Thr668 induced by Abeta on primary neuronal cultures". Paper presented in 11th International Conference on Alzheimer's and Parkinson's diseases, 2013.
  48. Rebelo, S.; Martins, F.; Santos, M.; Tenreiro, A. P.; Henriques, Ana Gabriela; Oliveira, J. M.; Carvalho, L. P.; et al. "Brain in motion". Paper presented in 8th FENS Forum of Neuroscience, 2012.
  49. Oliveira, J.; Henriques, Ana Gabriela; Martins, F.; Rebelo, S.; da Cruz e Silva, O.A.B.. "Aß mediated effects on APP phosphorylation.". Paper presented in Sinal 2012, 2012.
  50. Martins, F.; Rebelo, S.; Oliveira, J.; Henriques, Ana Gabriela; da Cruz e Silva, O.A.B.. "Abeta differentially modulates tau phosphorylation". Paper presented in Sinal 2012, 2012.
  51. Henriques, Ana Gabriela; Gomes, B.; Ruivo, R.; da Cruz e Silva, E.F.; da Cruz e Silva, O.A.B.. "Abeta disaggregating proteins counteract Abeta induced neurotoxic responses". Paper presented in Cell Signalomics, 2011.
  52. Henriques, Ana Gabriela; Vieira, S.; da Cruz e Silva Silva, E.F.; da Cruz e Silva, O.A.B.. "Aß as a signaling molecule that may regulate its own production". Paper presented in SINAL 2010 – 4th National Meeting on Signal Transduction, 2010.
  53. da Cruz e Silva, E.F.; Henriques, Ana Gabriela; Vintém, AP; da Cruz e Silva, O.A.B.. "PP1 inhibition by Abeta and aluminium a potential pathological mechanism in Alzheimer´s disease". Paper presented in ICAD, 2009.
  54. Domingues, S.C.T.S.; Henriques, Ana Gabriela; da Cruz e Silva, E.F.; da Cruz e Silva, O.A.B.. "Characterization of a novel neuronal splice variant of Alzheimer´s amyloid precursor binding protein FE65". Paper presented in 33rd FEBS Congress, 2008.
  55. Henriques, Ana Gabriela; Vieira, S.I.; Rebelo, S.; Crespo-López, M.E.; Oliveira, M.; da Cruz e Silva, E.F.; da Cruz e Silva, O. A. B.. "Abeta leads to intracellular sAPP accumulation at cytoskeleton associated vesicular-like densities". Paper presented in 33rd FEBS Congress, 2008.
    10.1055/s-0038-1677242
  56. Henriques, Ana Gabriela; Vieira, S.; Rebelo, S.; Domingues, S.C.T.C.; da Cruz e Silva, E.F.; da Cruz e Silva, O.A.B.. "Different amyloid precursor protein isoforms have distinct fates". Paper presented in 10th Reunião da Sociedade Portuguesa Neurociências, 2007.
  57. Henriques, Ana Gabriela; Vieira, S.I.; Rebelo, S.; Domingues, S.C.T.S.; da Cruz e Silva, E.F.; da Cruz e Silva, O.A.B.. "APP isoform specific-differences in metabolism". Paper presented in The 8th International Conference AD/PD 2007, 2007.
  58. Henriques, Ana Gabriela; Crespo-López, M.E.; da Cruz e Silva, E.F.. "Abeta effects on APP metabolism". Paper presented in 10th International Conference of Alzheimer´s Disease and Related Disorders, 2006.
  59. Domingues, S.C.T.C; Henriques, Ana Gabriela; Wu, W.; da Cruz e Silva, E.F.; da Cruz e Silva, O.A.B.. "Altered subcellular distribution of the Alzheimer’s Amyloid Precursor Protein under stress conditions". Paper presented in Cell Signalling World, 2006.
  60. Vintém, AP; Henriques, Ana Gabriela; Wu, W.; da Cruz e Silva, O.A.B.; Da Cruz E Silva, E.F.. "Protein phosphatase 1 may be a physiological target for Abeta". Paper presented in EBS Europhosphatases Conference, 2005.
    10.1158/1538-7445.am2017-4173
  61. Henriques, Ana Gabriela; Crespo-López, M.E.; Serafim, T.; da Cruz e Silva, E.F.; da Cruz e Silva, O.A.B.. "Multiple Abeta effects on the Azheimer´s amyloid precursor protein". Paper presented in FENS Forum 2004, 2004.
  62. Crespo-López, M.E.; Henriques, Ana Gabriela; Serafim, T.; Amorim, M.R.; da Cruz e Silva, E.F.; Da Cruz E Silva, O.A.B.. "Possible contributions of APP metabolism to Alzheimer’s disease pathology". Paper presented in I Simpósio International de Neurociências, 2004.
  63. Henriques, Ana Gabriela; da Cruz e Silva, E.F.; da Cruz e Silva, O.A.B.. "APP processing pathways can be differentially affected". Paper presented in 8ª Reunião da Sociedade Portuguesa de neurociências, 2003.
  64. Amador, F.C.; Henriques, Ana Gabriela; da Cruz e Silva, E.F.; da Cruz e Silva, O.A.B.. "Protein phosphatase 1: a candidate molecular marker for cellular stress". Paper presented in 8ª Reunião da Sociedade Portuguesa de neurociências, 2003.
  65. Amorim, M.R.; Henriques, Ana Gabriela; Crespo-López, M.E.; da Cruz e Silva, E.F.; da Cruz e Silva, O.A.B.. "Neuronal-like and non-neuronal cell lines respond differently to staurosporine treatment". Paper presented in 8ª Reunião da Sociedade Portuguesa de neurociências, 2003.
  66. Henriques, Ana Gabriela; da Cruz e Silva, E.F.; da Cruz e Silva, O.A.B.. "Cellular stress related markers in Alzheimer´s Disease". Paper presented in I Simpósio de Pós-graduação em Biociências, 2002.
  67. Henriques, Ana Gabriela; Rebelo, S.; da Cruz e Silva, E.F.; da Cruz e Silva, O.A.B.. "Cellular signalling and processing of the Alzheimer’s amyloid precursor protein". Paper presented in XII Congresso Nacional de Bioquímica, 2000.
Journal article
  1. Soares Martins, T.; Pelech, S.; Ferreira, M.; Pinho, B.; Leandro, K.; Pereira de Almeida, L.; Breitling, B.; et al. "Phosphoproteome Microarray Analysis of Extracellular Particles as a Tool to Explore Novel Biomarker Candidates for Alzheimer's Disease". International Journal of Molecular Sciences 25 3 (2024): 1584. https://doi.org/10.3390/ijms25031584.
    Published • 10.3390/ijms25031584
  2. Ferreira, Maria J. Cardoso; Martins, Tânia Soares; Alves, Steven R.; Rosa, Ilka Martins; Vogelgsang, Jonathan; Hansen, Niels; Wiltfang, Jens; et al. Corresponding author: Henriques, Ana Gabriela. "Bioinformatic analysis of the SPs and NFTs proteomes unravel putative biomarker candidates for Alzheimer's disease". PROTEOMICS (2023): http://dx.doi.org/10.1002/pmic.202200515.
    10.1002/pmic.202200515
  3. Gouveia, Marisol; Teixeira, Manuel; Schmidt, Cristine; Lopes, Mário; Trindade, Dário; Magalhães, Sandra; Henriques, Ana Gabriela; et al. "Impaired Extracellular Proteostasis in Patients with Heart Failure". Archives of Medical Research 54 3 (2023): 211-222. http://dx.doi.org/10.1016/j.arcmed.2023.02.001.
    10.1016/j.arcmed.2023.02.001
  4. Trindade, Dário; Cachide, Maria; Soares Martins, Tânia; Guedes, Sandra; Rosa, Ilka M.; da Cruz e Silva, Odete A.B.; Henriques, Ana Gabriela. "Monitoring clusterin and fibrillar structures in aging and dementia". Aging Brain 3 (2023): 100080. http://dx.doi.org/10.1016/j.nbas.2023.100080.
    Published • 10.1016/j.nbas.2023.100080
  5. Vaz, Margarida; Soares Martins, Tânia; Henriques, Ana Gabriela. "Extracellular vesicles in the study of Alzheimer's and Parkinson's diseases: Methodologies applied from cells to biofluids". Journal of Neurochemistry 163 4 (2022): 266-309. http://dx.doi.org/10.1111/jnc.15697.
    Published • 10.1111/jnc.15697
  6. Martins, Tânia Soares; Vaz, Margarida; Henriques, Ana Gabriela. "A review on comparative studies addressing exosome isolation methods from body fluids". Analytical and Bioanalytical Chemistry (2022): http://dx.doi.org/10.1007/s00216-022-04174-5.
    Published • 10.1007/s00216-022-04174-5
  7. Manuel Teixeira; Dário Alexandre Martins Trindade; Marisol Gouveia; Roberta Eller-Borges; Sandra Magalhães; Ana Duarte; Miriam Ferreira; et al. "Proteostasis Response to Protein Misfolding in Controlled Hypertension". Cells (2022): https://www.mdpi.com/2073-4409/11/10/1686.
    10.3390/cells11101686
  8. Soares Martins, Tânia; Marçalo, Rui; da Cruz e Silva, Cristóvão B.; Trindade, Dário; Catita, José; Amado, Francisco; Melo, Tânia; et al. "Novel Exosome Biomarker Candidates for Alzheimer's Disease Unravelled Through Mass Spectrometry Analysis". Molecular Neurobiology (2022): http://dx.doi.org/10.1007/s12035-022-02762-1.
    Published • 10.1007/s12035-022-02762-1
  9. Alves, Steven R.; da Cruz e Silva, Cristovao; Martins, Ilka; Henriques, Ana Gabriela; da Cruz e Silva, Odete A. B.. "A Bioinformatics Approach Toward Unravelling the Synaptic Molecular Crosstalk Between Alzheimer's Disease and Diabetes". Journal of Alzheimer's Disease (2022): https://publons.com/wos-op/publon/53817998/.
    10.3233/JAD-215059
  10. Soares Martins, Tânia; Marçalo, Rui; Ferreira, Maria; Vaz, Margarida; Silva, Raquel M.; Martins Rosa, Ilka; Vogelgsang, Jonathan; et al. "Exosomal Aß-Binding Proteins Identified by 'In Silico' Analysis Represent Putative Blood-Derived Biomarker Candidates for Alzheimer´s Disease". International Journal of Molecular Sciences 22 8 (2021): 3933. http://dx.doi.org/10.3390/ijms22083933.
    10.3390/ijms22083933
  11. Vaz, M.; Domingues, C.; Trindade, D.; Barra, C.; Oliveira, J.M.; Rosa, Ilka M.; da Cruz e Silva, O.A.B.; Henriques, Ana Gabriela. "IL-8 and MCP-1 Impact on Tau Phosphorylation and Phosphatase Activity". Current Alzheimer Research 17 11 (2021): 985-1000. http://dx.doi.org/10.2174/1567205017666201130091129.
    Published • 10.2174/1567205017666201130091129
  12. Soares Martins, Tânia; Trindade, Dário; Vaz, Margarida; Campelo, Inês; Almeida, Martim; Trigo, Guilherme; da Cruz e Silva, Odete A. B.; Henriques, Ana Gabriela. "Diagnostic and therapeutic potential of exosomes in Alzheimer's disease". Journal of Neurochemistry 156 2 (2020): 162-181. http://dx.doi.org/10.1111/jnc.15112.
    10.1111/jnc.15112
  13. Soares Martins, Tânia; Magalhães, Sandra; Rosa, Ilka Martins; Vogelgsang, Jonathan; Wiltfang, Jens; Delgadillo, Ivonne; Catita, José; et al. "Potential of FTIR Spectroscopy Applied to Exosomes for Alzheimer's Disease Discrimination: A Pilot Study". Journal of Alzheimer's Disease 74 1 (2020): 391-405. http://dx.doi.org/10.3233/jad-191034.
    10.3233/jad-191034
  14. Magalhães, S.; Trindade, D.; Soares Martins, T.; Rosa, I.M.; Delgadillo, I.; Goodfellow, B.J.; da Cruz e Silva, O.A.B; Henriques, Ana Gabriela; Nunes, A.. "Monitoring plasma protein aggregation during aging using conformation-specific antibodies and FTIR spectroscopy". Clinica Chimica Acta 502 (2020): 25-33. http://dx.doi.org/10.1016/j.cca.2019.11.025.
    10.1016/j.cca.2019.11.025
  15. Tânia Soares Martins; José Catita; Ilka Martins Rosa; Odete A. B. da Cruz e Silva; Ana Gabriela Henriques. "Exosome isolation from distinct biofluids using precipitation and column-based approaches". PLOS ONE 13 6 (2018): e0198820-e0198820. https://doi.org/10.1371/journal.pone.0198820.
    10.1371/journal.pone.0198820
  16. Oliveira, J.; Costa, M.; De Almeida, M.S.C.; Da Cruz E Silva, O.A.B.; Henriques, A.G.; Henriques, Ana. "Protein Phosphorylation is a Key Mechanism in Alzheimer's Disease". Journal of Alzheimer's Disease 58 4 (2017): 953-978. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021269018&partnerID=MN8TOARS.
    10.3233/JAD-170176
  17. Rosa, I.M.; Henriques, A.G.; Wiltfang, J.; Da Cruz E Silva, O.A.B.. "Putative Dementia Cases Fluctuate as a Function of Mini-Mental State Examination Cut-Off Points". Journal of Alzheimer's Disease 61 1 (2017): 157-167. http://www.scopus.com/inward/record.url?eid=2-s2.0-85036594156&partnerID=MN8TOARS.
    10.3233/JAD-170501
  18. Henriques, Ana. "Impact of Cytokines and Chemokines on Alzheimer's Disease Neuropathological Hallmarks.". Current Alzheimer research (2017): http://europepmc.org/abstract/med/28317487.
    10.2174/1567205014666170317113606
  19. Henriques, Ana. "Screening Younger Individuals in a Primary Care Setting Flags Putative Dementia Cases and Correlates Gastrointestinal Diseases with Poor Cognitive Performance.". Dementia and geriatric cognitive disorders (2017): http://europepmc.org/abstract/med/27907913.
    10.1159/000452485
  20. Oliveira, Joana Machado; da Cruz e Silva, Cristovao B.; Mueller, Thorsten; Martins, Tania Soares; Cova, Marta; da Cruz e Silva, Odete A. B.; Henriques, Ana Gabriela. "Toward Neuroproteomics in Biological Psychiatry: A Systems Approach Unravels Okadaic Acid-Induced Alterations in the Neuronal Phosphoproteome". Omics-a Journal of Integrative Biology 21 9 (2017): 550-563. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000411498000006&KeyUID=WOS:000411498000006.
    10.1089/omi.2017.0108
  21. Lopes, J.; Correia, M.; Martins, I.; Henriques, A. G.; Delgadillo, I.; da Cruz E Silva, O.; Nunes, A.. "FTIR and Raman Spectroscopy Applied to Dementia Diagnosis Through Analysis of Biological Fluids". J Alzheimers Dis 52 3 (2016): 801-12. https://content.iospress.com/articles/journal-of-alzheimers-disease/jad151163.
    10.3233/JAD-151163
  22. Henriques, A. G.; Müller, T.; Oliveira, J. M.; Cova, M.; da Cruz E Silva, C. B.; da Cruz E Silva, O. A.. "Altered protein phosphorylation as a resource for potential AD biomarkers". Sci Rep 6 (2016): 30319-30319. https://www.nature.com/articles/srep30319.
    10.1038/srep30319
  23. Henriques, Ana. "The effect of Abeta and PKC on actin network remodeling". Microscopy and Microanalysis (2015): https://doi.org/10.1017/S1431927614013841.
    10.1017/S1431927614013841
  24. Oliveira, Joana M.; Henriques, Ana Gabriela; Martins, Filipa; Rebelo, Sandra; da Cruz e Silva, Odete A. B.. "Amyloid-beta Modulates Both APP and Tau Phosphorylation". Journal of Alzheimers Disease 45 2 (2015): 495-507. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000351583900016&KeyUID=WOS:000351583900016.
    10.3233/JAD-142664
  25. Henriques, A.G.; Oliveira, J.M.; Carvalho, L.P.; da Cruz e Silva, O.A.B.. "Aß Influences Cytoskeletal Signaling Cascades with Consequences to Alzheimer’s Disease". Molecular Neurobiology 52 3 (2015): 1391-1407. http://www.scopus.com/inward/record.url?eid=2-s2.0-84942820792&partnerID=MN8TOARS.
    10.1007/s12035-014-8913-4
  26. Henriques, A. G.; Oliveira, J. M.; Gomes, B.; Ruivo, R.; da Cruz e Silva, E. F.; da Cruz e Silva, O. A. B.. "Complexing A beta Prevents the Cellular Anomalies Induced by the Peptide Alone". Journal of Molecular Neuroscience 53 4 (2014): 661-668. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000340473300015&KeyUID=WOS:000340473300015.
    10.1007/s12031-014-0233-7
  27. Baptista, Filipa I.; Henriques, Ana G.; Silva, Artur M. S.; Wiltfang, Jens; da Cruz e Silva, Odete A. B.. "Flavonoids as Therapeutic Compounds Targeting Key Proteins Involved in Alzheimer's Disease". Acs Chemical Neuroscience 5 2 (2014): 83-92. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000331780000002&KeyUID=WOS:000331780000002.
    10.1021/cn400213r
  28. Dominguesa, Sara C.; Konietzko, Uwe; Henriques, Ana Gabriela; Rebelo, Sandra; Fardilha, Margarida; Nishitani, Hideo; Nitsch, Roger M.; da Cruz e Silva, Edgar F.; da Cruz e Silva, Odete A. B.. "RanBP9 Modulates AICD Localization and Transcriptional Activity via Direct Interaction with Tip60". Journal of Alzheimers Disease 42 4 (2014): 1415-1433. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000343763000027&KeyUID=WOS:000343763000027.
    10.3233/JAD-132495
  29. Henriques, A. G.; Vieira, S. I.; da Cruz e Silva, O. A. B.. "Abeta Induces Abnormal Cytoskeletal Dynamics which are Reversible Upon Peptide Removal". Microscopy and Microanalysis 18 (2012): 23-24. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000309744500012&KeyUID=WOS:000309744500012.
    10.1017/S1431927612012779
  30. Domingues, S.C.; Henriques, A.G.; Fardilha, M.; Da Cruz E Silva, E.F.; Da Cruz E Silva, O.A.B.. "Identification and characterization of a neuronal enriched novel transcript encoding the previously described p60Fe65 isoform". Journal of Neurochemistry 119 5 (2011): 1086-1098. http://www.scopus.com/inward/record.url?eid=2-s2.0-81255160893&partnerID=MN8TOARS.
    10.1111/j.1471-4159.2011.07420.x
  31. da Cruz e Silva, Odete A. B.; Henriques, Ana Gabriela; Timoteo Santos Domingues, Sara Catarina; da Cruz e Silva, Edgar F.. "Wnt Signalling is a Relevant Pathway Contributing to Amyloid Beta-Peptide-Mediated Neuropathology in Alzheimer's Disease". Cns & Neurological Disorders-Drug Targets 9 6 (2010): 720-726. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000284621100007&KeyUID=WOS:000284621100007.
  32. Henriques, A.G.; Vieira, S.I.; Da Cruz E Silva, E.F.; Da Cruz E Silva, O.A.B.. "Aß promotes Alzheimer's disease-like cytoskeleton abnormalities with consequences to APP processing in neurons". Journal of Neurochemistry 113 3 (2010): 761-771. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950632324&partnerID=MN8TOARS.
    10.1111/j.1471-4159.2010.06643.x
  33. da Cruz e Silva, O.A.B.; Henriques, A.G.; Domingues, S.C.T.S.; da Cruz e Silva Silva, E.F.. "Wnt signalling is a relevant pathway contributing to amyloid Betapeptide-mediated neuropathology in alzheimer's disease". CNS and Neurological Disorders - Drug Targets 9 6 (2010): 720-726. http://www.scopus.com/inward/record.url?eid=2-s2.0-78649277730&partnerID=MN8TOARS.
  34. da Cruz e Silva, Edgar F.; Henriques, Ana Gabriela; Vintém, Ana Paula; da Cruz e Silva, Odete A.B.. "PP1 Inhibition By Aß Peptide And Aluminum As A Potential Pathological Mechanism In Alzheimer's Disease". Alzheimers & Dementia 5 4 (2009): e16-e16. http://dx.doi.org/10.1016/j.jalz.2009.07.074.
    10.1016/j.jalz.2009.07.074
  35. Vintém, A.P.B.; Henriques, A.G.; da Cruz e Silva, O.A.B.; da Cruz e Silva, E.F.. "PP1 inhibition by Aß peptide as a potential pathological mechanism in Alzheimer's disease". Neurotoxicology and Teratology 31 2 (2009): 85-88. http://www.scopus.com/inward/record.url?eid=2-s2.0-61849092013&partnerID=MN8TOARS.
    10.1016/j.ntt.2008.11.001
  36. Henriques, A.G.; Vieira, S.I.; Crespo-López, M.E.; de Oliveira, M.A.; da Cruz e Silva, E.F.; da Cruz e Silva, O.A.B.. "Intracellular sAPP retention in response to Aß is mapped to cytoskeleton-associated structures". Journal of Neuroscience Research 87 6 (2009): 1449-1461. http://www.scopus.com/inward/record.url?eid=2-s2.0-65549096821&partnerID=MN8TOARS.
    10.1002/jnr.21959
  37. Henriques, A.G.; Vieira, S.I.; Da Cruz E Silva, E.F.; Da Cruz E Silva, O.A.B.. "Aß hinders nuclear targeting of AICD and Fe65 in primary neuronal cultures". Journal of Molecular Neuroscience 39 1-2 (2009): 248-255. http://www.scopus.com/inward/record.url?eid=2-s2.0-74149091545&partnerID=MN8TOARS.
    10.1007/s12031-009-9192-9
  38. Henriques, A.G.; Vieira, S.I.; Rebelo, S.; Domingues, S.C.T.S.; Da Cruz E Silva, E.F.; Da Cruz E Silva, O.A.B.; Henriques, Ana Gabriela; et al. "Isoform specific amyloid-ß protein precursor metabolism". Journal of Alzheimer's Disease 11 1 (2007): 85-95. http://www.scopus.com/inward/record.url?eid=2-s2.0-33847706505&partnerID=MN8TOARS.
  39. Domingues, S.C.T.S.; Henriques, A.G.; Wu, W.; Da Cruz E Silva, E.F.; Da Cruz E Silva, O.A.B.. "Altered subcellular distribution of the Alzheimer's amyloid precursor protein under stress conditions". Annals of the New York Academy of Sciences 1096 (2007): 184-195. http://www.scopus.com/inward/record.url?eid=2-s2.0-34247253057&partnerID=MN8TOARS.
    10.1196/annals.1397.085
  40. Henriques, A.G.; Domingues, S.C.T.S.; Fardilha, M.; Da Cruz E Silva, E.F.; Da Cruz E Silva, O.A.B.; Henriques, AG; Domingues, SCTS; et al. "Sodium azide and 2-deoxy-D-glucose-induced cellular stress affects phosphorylation-dependent AßPP processing". Journal of Alzheimer's Disease 7 3 (2005): 201-212. http://www.scopus.com/inward/record.url?eid=2-s2.0-21444455414&partnerID=MN8TOARS.
  41. Amador, F.C.; Henriques, A.G.; Da Cruz E Silva, O.A.B.; Da Cruz E Silva, E.F.. "Monitoring protein phosphatase 1 isoform levels as a marker for cellular stress". Neurotoxicology and Teratology 26 3 (2004): 387-395. http://www.scopus.com/inward/record.url?eid=2-s2.0-2042447806&partnerID=MN8TOARS.
    10.1016/j.ntt.2003.12.007
  42. Da Cruz E Silva, O.A.B.; Fardilha, M.; Henriques, A.G.; Rebelo, S.; Vieira, S.; Da Cruz E Silva, E.F.; Silva, OABDE; et al. "Signal transduction therapeutics: Relevance for Alzheimer's disease". Journal of Molecular Neuroscience 23 1-2 (2004): 123-142. http://www.scopus.com/inward/record.url?eid=2-s2.0-4344704079&partnerID=MN8TOARS.
    10.1385/JMN:23:1-2:123
  43. Rebelo, S.; Henriques, A.G.; Da Cruz E Silva, E.F.; Da Cruz E Silva, O.A.B.. "Effect of Cell Density on Intracellular Levels of the Alzheimer's Amyloid Precursor Protein". Journal of Neuroscience Research 76 3 (2004): 406-414. http://www.scopus.com/inward/record.url?eid=2-s2.0-2342473913&partnerID=MN8TOARS.
    10.1002/jnr.20091
Thesis / Dissertation
  1. "Antunes, Carla. Relatório de estágio em assuntos regulamentares na Pharmaissues Consultoria, Lda". Master, Universidade de Aveiro Departamento de Ciências Médicas, 2023.
  2. "Hanchar, Vlada. Programming clinical data datasets for regulatory submission of Phase I Clinical Trials". Master, Universidade de Aveiro Departamento de Ciências Médicas, 2023. https://ria.ua.pt/bitstream/10773/39366/1/Documento_Vlada_Hanchar.pdf.
  3. "Ravella, Edite. Report of the internship at the biobank of iBiMED". Master, Universidade de Aveiro Departamento de Ciências Médicas, 2023. http://hdl.handle.net/10773/39297.
  4. "Medeiros, João. Relatório e Estágio de Coordenação em Investigação Clínica em dois Hospitais Parceiros da Blueclinical Crp". Master, Universidade Nova de Lisboa Faculdade de Ciências Médicas, 2022. http://hdl.handle.net/10362/145821.
  5. "Avidos, Filipa. Bioinformatic identification of exosomal phosphospecific biomarkers candidates for Alzheimer's disease". Master, Universidade de Aveiro Departamento de Ciências Médicas, 2022. http://hdl.handle.net/10773/34477.
  6. "Soure, Inês. Study of the protein cargo of extracellular vesicles released by Acute Myeloid Leukemia cell lines". Master, Universidade de Aveiro Departamento de Química, 2022. http://hdl.handle.net/10773/35132.
  7. "Ferraz, Filipa. Impact of exercise on the exosomal proteome: quest for the exercise pill". Master, Universidade de Aveiro Departamento de Ciências Médicas, 2022. http://hdl.handle.net/10773/34534.
  8. "Mendes, Adriana. Relatório de estágio em Coordenação de Estudos Clínicos no C.H.U.C, E.P.E". Master, Universidade de Aveiro Departamento de Ciências Médicas, 2021. http://hdl.handle.net/10773/33827.
  9. "Alves, Micael. Curricular Internship Report in an Academic Clinical Trials Unit - CRU2C". Master, Universidade de Aveiro Departamento de Ciências Médicas, 2021. http://hdl.handle.net/10773/33828.
  10. "Leitão, Inês. Internship Report in Clinical Trials Coordination at IPO-Porto". Master, Universidade de Aveiro Departamento de Ciências Médicas, 2021.
  11. "Ferreira, Maria José. Identification of novel biomarkers candidates for Alzheimer's disease by bioinformatic analysis". Master, Universidade de Aveiro Departamento de Ciências Médicas, 2021. http://hdl.handle.net/10773/33853.
  12. "Pereira, Carla. Dinamização do banco de tumores do IPO Lisboa: A Caminho da Referência Nacional". Master, Universidade Nova de Lisboa, 2021. http://hdl.handle.net/10362/117591.
  13. "Machado, Joana. Phosphorylation mediated events in biomarker discovery for Alzheimer's disease". PhD, Universidade de Aveiro Departamento de Ciências Médicas, 2021. http://hdl.handle.net/10773/30913.
  14. "Vaz, Margarida. Chemokines effect on kinases and phosphatases involved in Alzheimer's disease pathology". Master, Universidade de Aveiro Departamento de Ciências Médicas, 2019. http://hdl.handle.net/10773/28407.
  15. "Amaral, Inês. Analysis of IncRNAs expression in monocytes and osteoclasts of rheumatoid arthritis patients". Master, Universidade de Aveiro Departamento de Ciências Médicas, 2019. http://hdl.handle.net/10773/27039.
  16. "Marçalo, Rui. Exosomal proteomes as a source for biomarker discovery in Alzheimer's disease". Master, Universidade de Aveiro Departamento de Ciências Médicas, 2018. http://hdl.handle.net/10773/25180.
  17. Martins, Tânia Cristina Soares. "Exosomes as tools for biomarker discovery". Master, 2017. http://hdl.handle.net/10773/21996.
  18. "Ferreira, Daniela. Influence of substrates composition on immunomodulation by MSCs". Master, Universidade de Aveiro Departamento de Ciências Médicas, 2016. http://hdl.handle.net/10773/16048.
  19. Guedes, Sandra Daniela Silva. "Testing a dementia risk group for polymorphisms in inflammation-related genes". Master, 2016. http://hdl.handle.net/10773/18512.
  20. Domingues, Catarina de Barros Pinto Salvador. "Chemokines impact in Alzheimer's disease". Master, Universidade de Aveiro Departamento de Ciências Médicas, 2015. http://hdl.handle.net/10773/16081.
  21. "Fernandes, Lurdes. Modulation of the sensitivity to chemotherapeutic drugs through epigenetic mechanisms". Master, Universidade de Aveiro Departamento de Ciências Médicas, 2015. http://hdl.handle.net/10773/21531.
  22. "Rodrigues, Joana Matos. From genes to radioresistance in head and neck squamous cell carcinoma". Master, Universidade de Aveiro Departamento de Ciências Médicas, 2015. https://opac.ua.pt/cgi-bin/koha/opac-detail.pl?biblionumber=279767.
  23. Barra, Cátia Isabel de Almeida. "Inflammatory biomarkers in Alzheimer's disease". Master, 2014. http://hdl.handle.net/10773/13277.
  24. Cova, Marta Alexandra Mendonça Nóbrega. "Bioinformatic analysis of the neuronal phosphoproteome". Master, 2013. http://hdl.handle.net/10773/11623.
  25. Almeida, João Carlos Moutinho de. "DNA methylation as a potential biomarker for Alzheimer disease". Master, 2013. http://hdl.handle.net/10773/13261.
  26. Martins, Maria Inês Morgado Oliveira. "Evolution and functional relevance of Ataxin-3 paralogues". Master, 2012. http://hdl.handle.net/10773/9745.
  27. Carvalho, Liliana Patrícia Rodrigues de. "Genetic profiling of ApoE in dementia". Master, 2012. http://hdl.handle.net/10773/10720.
  28. Oliveira, Joana Machado de. "Abnormal protein phosphorylation in Alzheimer's disease". Master, 2011. http://hdl.handle.net/10773/7388.
  29. Henriques, Ana Gabriela da Silva Cavaleiro. "Aß biology and its contribution to Alzheimer's disease". PhD, 2009. http://hdl.handle.net/10773/949.
  30. Henriques, Ana Gabriela da Silva Cavaleiro. "O efeito do stress celular na proteína precursora de amilóide de Alzheimer = The effect of cellular stress on the Alzheimer's amyloid precursor protein". Master, 2003. http://hdl.handle.net/10773/4210.
  31. Henriques, Ana Gabriela da Silva Cavaleiro. "O efeito do stress celular na proteína precursora de amilóide de Alzheimer". Master, 2003. http://hdl.handle.net/10773/18932.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/06/23 Phosphoproteome analysis of blood-derived extracellular vesicles unveils putative biomarker candidates for AD. / Soares Martins T., Rosa I.M., da Cruz e Silva O.A.B. and Henriques A.G. (2023) 2nd Meeting of the Portuguese Network on Extracellular Vesicles
Universidade Nova de Lisboa (Lisboa, Portugal)
2023/06/16 Extracellular vesicles as an emerging source of biomarkers for AD. / Henriques, A.G. (2023) Workshop on Novel diagnostic tools for Alzheimer's disease
Universidade de Aveiro (Aveiro, Portugal)
2023/05/25 Blood-derived extracellular vesicles metabolic signatures in Alzheimers disease. / Soares Martins T., Ferreira M., Magalhães S., Vogelgsang J., Breiltling B., Wiltfang J., da Cruz e Silva O.A.B., Nunes A. and Henriques A.G. (2023) VI Symposium iBiMED
Universidade de Aveiro (Aveiro, Portugal)
2023/03/30 Subjecting blood-derived extracelular vesicles to FTIR spectroscopy towards AD diagnosis. / Soares Martins T., Ferreira M., Magalhães S., Vogelgsang J., Breitling B., Hansen N., Esselmann H., Wiltfang J., da Cruz e Silva, O.A.B., Nunes A. and Henriques A.G. (2023) AD/PD 2023
(Gothenburg, Sweden)
2022/02/23 Identification of novel exosomal AD biomarkers through Mass Spectrometry analysis. / Soares Martins T., Henriques A.G. (2022) MEDISIS
iBiMED, University of Aveiro (Aveiro, Portugal)
2022/02/16 A spectroscopic study of age-related changes in protein conformation in biological samples. / Magalhães S., Trindade D., Almeida I., Soares Martins T., Rosa I.M., Martins F., Camões F., Soares A.R., da Cruz e Silva O.A.B., Henriques A.G., Rebelo S., Goodfellow B.J., Nunes A. (2022) 3rd MMCS: Shaping Medicinal Chemistry for the New Decade
Sapienza Università di Roma (Rome, Italy)
2021/09/13 Proteomic comparison of blood-derived exosomes isolated using precipitation and column-based approaches - Flash presentation. / Soares Martins T., Marçalo R., da Cruz e Silva C.B., Catita J., Amado F., Melo T., Rosa I.M., da Cruz e Silva O.A.B., Henriques A.G. (2021) First Meeting of the Portuguese Network on Extracellular Vesicles (PNEV)
i3s, Porto (Porto, Portugal)
2020/12/08 Comparision of methods for EVs isolation from peripheral biofluids. / Henriques A.G. (2020) First Workshop of the Portuguese Network on Extracellular Vesicles: EVs in Health and Disease
Instituto de Investigação e Inovação em Saúde (Portugal)
2020/09/26 Alzheimer's disease cases discrimination by FTIR spectroscopy of exosomes. / Soares Martins T., Magalhães S., Rosa I.M., Vogelgsang J., Wiltfang J., da Cruz e Silva O.A.B., Nunes A., Henriques A.G. (2020). 34ª Reunião do Grupo de Estudos de Envelhecimento Cerebral e Demência
(Portugal)
2019/10 Emotions, neurochemistry and circulating extracellular vesicles: all come with chronic aerobic physical exercise / Pereira, F., Rodrigues M., Reis J., Soares E., Ferreira H., Pita I., Viana S. D., Lemos C., Lima N., Soares Martins T., Catita J., Henriques A.G., Zuzarte M., Martins Marques T., Ribeiro Rodrigues T., Girão H., Aguiar A. and Fontes Ribeiro C. (2019). SfN Neuroscience 2019
(Chicago, United States)
2019/10 Neuronal phosphoproteome targets responsive to phosphatase inhibition. / Oliveira J., Soares Martins T., da Cruz e Silva C., Müller T., Cova M., da Cruz e Silva O.A.B. and Henriques A.G. (2019). SINAL Meeting 2019
(Portugal)
2019/06/06 Fourier Transformed Infrared Spectroscopy of Extracellular Vesicles as a Diagnostic Tool for Alzheimer's Disease - Flash presentation / Soares Martins T., Magalhães S., Rosa I.M., Vogelgsang J., Wiltfang J., Delgadillo I., Catita J., da Cruz e Silva O.A.B., Nunes A. and Henriques A.G. (2019) GEIVEX
(Granada, Spain)
2016/11 Phosphoproteins as potential novel Alzheimer’s disease biomarkers / Henriques A.G., Müller T., Oliveira J.M., Cova M., da Cruz e Silva C.B. and da Cruz e Silva O.A.B. (2016). Congresso Neurologia
(Portugal)
2013/12 Potential of FTIR in the identification of Alzheimer biomarkers. SINAL 2013, 7th National Meeting on Cell Signaling / Silva R., Henriques A.G., Oliveira J.M., Carvalho L., Rosa I., Delgadilho I., da Cruz e Silva O.A.B. and Nunes A. (2013). SINAL 2013
(Portugal)
2013/09 The molecular basis underlying actin network remodelling / Henriques A.G., Carvalho l., Oliveira J.M. and da Cruz e Silva, O.A.B. (2013). Microscopy at the Frontiers of Science - MFS2013
(Spain)
2013 Biomarcadores da doença de Alzheimer numa coorte portuguesa – complementaridade com informação clínica, imagiológica e genética / Barreto R., Ruano L., Moreira S., Alves J., Cruz V., Pais J., Henriques A.G., Carvalho L., Rebelo S. and da Cruz e Silva, O. (2013). Congresso de Neurologia 2013
(Portugal)
2013 Identification of Alzheimer biomarkers with mid-infrared spectroscopy– exploratory study / Silva R.C., Henriques A.G., Oliveira J.M., Carvalho L., Rosa I., Delgadilo I., da Cruz e Silva O.A.B. and Nune A. (2013). XIII Reunião da Sociedade Portuguesa de Neurociências
(Portugal)
2012 Application of a management framework to evaluate the phosphoproteome of primary neuronal cultures / Henriques A.G., Müller T., Cova M., Oliveira J.M. and da Cruz e Silva O.A.B (2012). Sinal 2012
(Portugal)
2011/10 Abeta leads to abnormal cytoskeletal dynamics in different cellular models / Henriques A.G., Vieira S.I. and da Cruz e Silva O.A.B. (2011). Microscope frontiers of science
(Portugal)
2010 A novel function for Abeta as a transcriptional regulation factor / Henriques A.G., Viera S., da Cruz e Silva E.F. and da Cruz e Silva, O.A.B. (2010). 24ª Reunião Grupo de Estudos de Envelhecimento Cerebral e Demência (GEECD)
(Portugal)
2008 Molecular advances in APP biology / Rebelo S., Vieira S.I., Henriques A.G., Domingues S.C., Guimarães S., and da Cruz e Silva, O.A.B. (2008). 22th Meeting of the GEECD
(Portugal)
2004/07 Isoform specific responses of the Alzheimer’s Amyloid Precursor Protein / Henriques A.G., Santos S., Rebelo S., Vieira S., da Cruz e Silva E.F. and da Cruz e Silva O.A.B. (2004). 9th International Conference of Alzheimer´s Disease and Related Disorders
(Philadelphia, United States)
2004 Altered signal transduction cascades contribute to human pathologies / Amador F. C., Henriques A.G., Santos S.C.T., Vintém A.P., Conde R.M., da Cruz e Silva O.A.B. and da Cruz e Silva, E.F. (2004). III Simpósio de Pós-graduação em Biociências
(Portugal)
2003 Monitorização de marcadores moleculares / Crespo-López M.E., Henriques A.G., da Cruz e Silva E.F. and da Cruz e Silva O.A.B. (2003). 17ª Reunião do Grupo de Estudos de Envelhecimento Cerebral e Demência (GEECD)
(Portugal)
2003 Intracellular protein processing and expression under basal and stress conditions / Henriques A.G., Amador F.C., Amorim M., da Cruz e Silva E.F. and da Cruz e Silva O.A.B. (2003). II Simpósio de Pós-graduação em Biociências
(Portugal)
2002 Cellular stress leads to altered intracellular protein expression and metabolism / Henriques A.G., Crespo-López M.E., da Cruz e Silva E.F. and da Cruz e Silva O.A.B. (2002). XII Congresso Nacional de Bioquímica
(Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2020/09 - Current Unravelling Abeta impact on exosome secretion and signal pathways relevant to Alzheimer’s disease pathogenesis - ExoSigAD
Supervisor of Margarida Vaz
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2023/09 - 2024 Investigation astrocyte neurotoxicity in the context of X-linked adrenoleukodystrophy
Supervisor of Bruno Cruz
 Molecular Biomedicine (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal

Center for Brain Research Medical University of Vienna, Austria
2023/09 - 2024 Test of phosphospecific targets in Alzheimer's disease models
Supervisor of Beatriz Pinho
 Molecular Biomedicine (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2019 - 2024 Blood-derived exosomes for biomarker discovery in AD
Supervisor of Tânia Soares Martins
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017 - 2024 The role of BIN1 in Alzheimer's Disease and Type 2 Diabetes
Co-supervisor of Maria Cachide
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017 - 2024 The role of metal induced protein phosphorylation in neuropathology related protein aggregation
Co-supervisor of André Nadais
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2022 - 2023/12/15 Relatório de estágio em assuntos regulamentares na Pharmaissues Consultoria
Supervisor of Carla Antunes
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2022/09 - 2023/07/05 Report of the internship at the biobank of iBiMED
Supervisor of Edite Ravella
Universidade de Aveiro, Portugal
2022/09 - 2023/06/06 Programming clinical data datasets for regulatory submission of Phase I Clinical Trials
Supervisor of Vlada Hancha
 Master degree in Clinical Bioinformatics (Master)
Universidade de Aveiro, Portugal
2021/09 - 2022/11/24 Relatório de estágio de coordenação em investigação clínica em dois hospitais parceiros da Blueclinical CRP
Supervisor of João Medeiros
 Master in Clinical Research Management (Master)
Universidade Nova de Lisboa, Portugal
2021/09 - 2022/07/29 Bioinformatic identification of exosomal phosphospecific biomarkers candidates for Alzheimer's disease
Supervisor of Filipa Avidos
 Biology (Master)
Universidade de Aveiro, Portugal
2021/09 - 2022/07/28 Study of the protein cargo of extracellular vesicles released by Acute Myeloid Leukemia cell lines
Co-supervisor of Inês Soure
Universidade de Aveiro Departamento de Química, Portugal
2021/09 - 2022/07/26 Impact of exercise on the extracellular vesicle's proteome
Supervisor of Filipa Ferraz
 Biomedicine (Master)
Universidade de Aveiro, Portugal
2020/06 - 2021/12/07 Relatório de estágio em Coordenação de Estudos Clínicos no C.H.U.C, E.P.E
Supervisor of Adriana Lopes Costa Mendes
 Investigação Clínica (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2020/06 - 2021/12/07 Curricular Internship Report in an Academic Clinical Trials Unit - CRU2C
Supervisor of Micael António Cardoso Alves
 Clinical Investigation (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2020/06 - 2021/07/22 Internship report in clinical trials coordination at IPO-Porto
Supervisor of Inês Ferraz Moreira Leitão
 Clinical Research (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2020/09 - 2021/07/21 Identification of novel biomarkers candidates for Alzheimer's disease by bioinformatic analysis
Supervisor of Maria José Ferreira
Molecular Biomedicine (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2020 - 2021/05/04 Dinamização do Banco de Tumores do IPO Lisboa: a caminho da referência nacional
Supervisor of Carla Sofia Alves Pereira
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2011 - 2021/02/23 Protein phosphorylation - a key event in AD pathogenesis (the PhD student integrated the medicine course)
Supervisor of Joana Oliveira
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2018 - 2019/07/18 Analysis of IncRNAs expression in monocytes and osteoclasts of rheumatoid arthritis patients
Supervisor of Inês Filipa Abrunhosa Amaral
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2018 - 2019 Chemokines effect on kinases and phosphateses involved in AD pathology
Supervisor of Margarida Vaz
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017 - 2018 Exosomal proteomes as a source for biomarker discovery in Alzheimer's disease
Supervisor of Rui Marçalo
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2016 - 2017 Exosomes as tools for biomarker discovery
Supervisor of Tânia Martins
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2015 - 2016 Testing a dementia risk group for polymorphisms in inflammation-related genes
Supervisor of Sandra Guedes
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2014 - 2015 Modulation of the sensitivity to chemotherapeutic drugs through epigenetic mechanisms
Co-supervisor of Lurdes Fernandes
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2014 - 2015 Influence of substrates composition on immunomodulation by MSCs
Co-supervisor of Daniela Ferreira
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2014 - 2015 From genes to radioresistance in head and neck squamous cell carcinoma
Co-supervisor of Joana Matos Rodrigues
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2014 - 2015 Chemokines impact in Alzheimer's disease
Supervisor of Catarina Domingues
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2013 - 2014 Inflammatory biomarkers in Alzheimers disease
Supervisor of Cátia Barra
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2012 - 2013 DNA methylation as a potential biomarker for Alzheimer disease
Supervisor of João Almeida
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2012 - 2013 Bioinformatic analysis of the neuronal phosphoproteome
Supervisor of Marta Cova
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2011 - 2012 Genetic profiling of ApoE in dementia
Supervisor of Liliana Carvalho
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2011 - 2012 Evolution and functional relevance of Ataxin-3 paralogues
Co-supervisor of Maria Inês Morgado
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2010 - 2011 Abnormal protein phosphorylation in Alzheimer's disease
Supervisor of Joana Oliveira
Universidade de Aveiro Departamento de Ciências Médicas, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/06/16 - 2023/06/17 Workshop on Novel Diagnostic Tools for Alzheimer's disease (2023/06/16 - 2023/06/17)
Workshop (President of the Organising Committee)
 Universidade de Aveiro, Portugal
2022/02/23 - 2022/02/23 MEDISIS open day 2022 (2022/02/23 - 2022/02/23)
Conference (Member of the Organising Committee)
 Universidade de Aveiro Instituto de Biomedicina, Portugal
2019 - 2022 Brain Awareness Week for Aveiro Region / Semana Internacional do Cérebro para a Região de Aveiro. Activities: "Os Cientistas vão à Escola", palestra e outras atividades interactivas. Março 2015, Março 2019, Março 2022 (2019 - 2019)
Other
 Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2020/09/08 - 2020/09/10 Formation in Problem Based Learning at DCM (PBL@DCM) (2020/09/08 - 2020/09/10)
Other (Member of the Organising Committee)
 Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2018/03/16 - 2018/03/16 Science Coffee on "Neurodegenerative Diseases" /Café de Ciência “Doenças Neurodegenerativas”, Joint Initiative Fábrica da Ciência - UA. Organizador, Moderador e Orador. (2019)
Other
2013/12 - 2013/12/07 SINAL 2013, 7th National Meeting on Cell Signaling. (2013/12/06 - 2013/12/07)
Meeting (Member of the Organising Committee)
 Universidade de Aveiro, Portugal
2008 - 2012 Brain Awareness Week for Aveiro Region / Semana Internacional do Cérebro para a Região de Aveiro. ¿Os Cientistas vão à Escola¿, palestras e outras atividades interactivas que decorreram em Março. (2008 - 2012)
Other (Member of the Organising Committee)
2007/07/24 - 2007/07/28 Europhosphatases 2007, Protein phosphatases in health and disease – EMBO conference/FEBS workshop. Participation in the Organization. (2007/07/24 - 2007/07/28)
Conference (Other)
2003/06/13 - 2003/06/14 17a Reunião do Grupo de Estudos do Envelhecimento Cerebral e Demência (GEECD). Member of the Organizing Committee. (2003/06/13 - 2003/06/14)
Meeting (Member of the Organising Committee)
2003/06/12 - 2003/06/13 8a Reunião da Sociedade Portuguesa de Neurociências. Member of the Organizing Committee. (2003/06/12 - 2003/06/13)
Meeting (Member of the Organising Committee)
2002/09/26 - 2002/09/28 1st workshop, DIADEM-Early Diagnosis of Alzheimer's Disease and Related Dementia. Participation in the Organization. (2002/09/26 - 2002/09/28)
Workshop (Other)
 Universidade de Aveiro Departamento de Biologia, Portugal
2002/09/12 - 2002/09/14 Simpósio ‘Novel Therapeutic Opportunities in Neurodegenerative Disease. Participation in the Organization. (2002/09/12 - 2002/09/14)
Symposium (Other)
 Universidade de Aveiro Departamento de Biologia, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2022/04/24 - Current Science Coffee on "Neurodegenerative Diseases" /Café de Ciência "Diagnóstico molecular na Doença de Alzheimer, uma ferramenta valiosa", Joint Initiative Fábrica da Ciência - UA. Orador.
2017 - Current Session Chair @ III Post-Graduate Symposium on Biomedicine.
Symposium
Universidade de Aveiro Instituto de Biomedicina, Portugal
2003/02/11 - Current Protein Phosphorylation in health and disease
Workshop
 Protein Phosphorylation in health and disease
Universidade de Aveiro, Portugal
2002/12/10 - Current Pieces and Parts: a primer on Brain dissection from discrete regions to micronuclei
Workshop
 Pieces and Parts: a primer on Brain dissection from discrete regions to micronuclei
Universidade de Aveiro, Portugal
2023/09/14 - 2023/09/14 Advanced course - "Biobanks: enhancing health research" - 1st edition - Round table participant Advanced course - "Biobanks: enhancing health research"
Universidade de Lisboa Instituto de Medicina Molecular, Portugal
2023/06/23 - 2023/06/23 2nd Meeting of the Portuguese Network on Extracellular Vesicles (PNEV) - Chair at session IV
Conference
 2nd Meeting of the Portuguese Network on Extracellular Vesicles (PNEV)
2023/06/17 - 2023/06/17 Workshop on Novel diagnostic tools for Alzheimer's disease - Chair at session V
Workshop
 Workshop on Novel diagnostic tools for Alzheimer's disease
2021/09/13 - 2021/09/14 First Meeting of the Portuguese Network on Extracellular Vesicles (PNEV)
Conference
 First Meeting of the Portuguese Network on Extracellular Vesicles (PNEV)
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/07/26 - 2021/07/30 Alzheimer's Association International Conference - AAIC 2021
Conference
 Alzheimer's Association International Conference - AAIC 2021
Alzheimer's Association, United States
2021/07/09 - 2021/07/09 UA Research summit - 2021
Conference
 UA Research Summit - 2021
Universidade de Aveiro, Portugal
2020/12/18 - 2020/12/18 First Workshop of the Portuguese Network on Extracellular Vesicles: EVs in Health and Disease
Conference
 First Workshop of the Portuguese Network on Extracellular Vesicles: EVs in Health and Disease
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020/07/27 - 2020/07/31 Alzheimer's Association International Conference - AAIC 2020
Conference
 Alzheimer's Association International Conference - AAIC 2020
Alzheimer's Association, United States
2020/02/27 - 2020/02/27 Chairman in the Debate on Ethics: "Genetic Manipulation" at the XV Encontro Nacional de Estudantes de Engenharia Biomédica.
Meeting
 XV Encontro Nacional de Estudantes de Engenharia Biomédica
Universidade de Aveiro, Portugal
2020 - 2020 Debate moderator - Ethics: Genetic Manipulation
Other
 XV Encontro Nacional de Estudantes de Engenharia Biomédica (COENEEB 2020)
Associação Nacional de Estudantes de Engenharia Biomédica, Portugal
2019/04/29 - 2019/04/30 XPERIMENTA UA - Participation in the scientists' activities.
Other
Universidade de Aveiro, Portugal
2019/02/14 - 2019/02/15 Biotech Pharma Summit: Biobanking 2019 - This event brought the world’s leading experts in biorepositories, policy makers, and scientists to discuss the future advances in the field of biobanking.
Conference
 Biobanking 2019
2016/09/13 - 2016/09/16 Europe Biobank Week - Conference about biobanking and biopreservation of human biological materials for research and development purposes.
Conference
 Europe Biobank Week
2015/04/20 - 2015/04/24 Course of Fundamentals and Applications in Flow Cytometry
Workshop
 Fundamentals and Applications in Flow Cytometry
Instituto Gulbenkian de Ciência, Portugal
2015/03/21 - 2015/03/21 “Chairmain” of the debate: “Conhecer o Cérebro”.
Other
 Semana Internacional do Cérebro
2014/02/15 - 2014/02/15 Palestra sobre a temática: “Alzheimer o puzzle complexo”. Instituto de Educação e Cidadania de Mamarrosa.
Other
2013/09/19 - 2013/09/20 Pratical course in Flow Cytometry
Workshop
2012/07 - 2013/07 Colaborador na Academia de Verão, Grupo de Neurociências, CBC, UA. “Semana Aberta no Laboratório de Neurociências – Hands on”, Julho 2012 e 2013.
Other
Universidade de Aveiro Departamento de Biologia, Portugal
2013/01/21 - 2013/01/22 Slicescope, a microscope for Recording Electrophysiology measurements and Micromanipulation
Workshop
 Slicescope, a microscope for Recording Electrophysiology measurements and Micromanipulation
2010/06/03 - 2010/06/04 Biomarkers in the early diagnosis of neurodegenerative disorders
Workshop
 Biomarkers in the early diagnosis of neurodegenerative disorders
2009/03 - 2009/03 Henriques A.G. and Vieira S.I. “Doença de Alzheimer”, Mesa Redonda sobre "Doenças do Cérebro" . Fábrica da Ciência da Universidade de Aveiro e Instituto de Educação e Cidadania da Mamarrosa
Round table
2008/03/16 - 2008/03/16 Palestra sobre a temática: “Alzheimer, o homem que ninguém esquece”.
Other
 Semana Internacional do Cérebro
2006/07/25 - 2006/07/26 Training course in Zeiss confocal microscopy
Other
 Training course in Zeiss confocal microscopy
Universidade de Aveiro, Portugal
2002/09/26 - 2002/09/28 DIADEM (Early Diagnosis of Alzheimer´s disease and related Dementia) - First progress report meeting
Workshop
 DIADEM (Early Diagnosis of Alzheimer´s disease and related Dementia)
2002/05/06 - 2002/05/10 Oxidative stress and Disease – An advanced practical course
Workshop
 Oxidative stress and Disease – An advanced practical course
Universidade de Lisboa Faculdade de Farmácia, Portugal
2001/07/09 - 2001/07/13 A Practical Course on Identification of Apoptosis Mitochondrial Pathway
Workshop
 A Practical Course on Identification of Apoptosis Mitochondrial Pathway
Universidade de Lisboa Faculdade de Farmácia, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2023/12/21 The importance of insulin signaling in Alzheimer's disease
(Thesis) Arguer
 Steven Alves (PhD)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2023/12/15 Relatório de estágio em assuntos regulamentares na Pharmaissues Consultoria, Lda
Supervisor
 Carla Patrícia Quintaneiro Antunes (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2023/12/15 Relatório de Estágio em Coordenação de Ensaios Clínicos de Oncologia no IPO-Porto
President of the jury
 Mariana Magalhães de Oliveira Ribeiro (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2023/12/07 Dendritic cell-based vaccines: Evaluating their anti-tumoral efficacy
President of the jury
 Gonçalo Miguel Fernandes Simões (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2023/11/17 Exosome dynamics in stress-driven brain pathologies: a novel link between depression and Alzheimer's disease
(Thesis) Arguer
 Ana Patrícia Gomes (PhD)
Universidade do Minho Escola de Ciências da Saúde, Portugal
2023/07/07 Programação de datasets de dados clínicos para submissão regulamentar de Ensaios Clínicos de Phase I
Supervisor
 Vlada Hancha (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2023/07/05 Relatório de Estágio no Biobanco do iBiMED
Supervisor
 Edite Ravella (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2022/11/24 Relatório de Estágio de Coordenação em Investigação Clínica em dois Hospitais Parceiros da Blueclinical Crp
Supervisor
 João Manuel da Silva Medeiros (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2022/07/29 Bioinformatic identification of exosomal phosphospecific biomarkers candidates for Alzheimer's disease
Supervisor
 Filipa Maria Avidos Silva (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2022/07/26 Impact of exercise on the extracellular vesicle's proteome
Supervisor
 Filipa Gomes Ferraz (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2021/12/09 Production and purification of pDNA as a biopharmaceutical with application in oncology
President of the jury
 Carolina Freitas Pires (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2021/12/09 Identification of novel biomarkers candidates for Alzheimer's disease by bioinformatic analysis
Supervisor
 Maria José Cardoso Ferreira (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2021/12/07 Curricular Internship Report in an Academic Clinical Trials Unit - CRU2C
Supervisor
 Micael Alves (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2021/11/24 Insight into the differentiation of spinal dorsal horn neurons
(Thesis) Arguer
 João Pedro Baltar Guimarães (Master)
Universidade do Porto, Portugal
2021/07/23 Desenvolvimento Clínico de Medicamentos
President of the jury
 Rute Inês Domingues Gil (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2021/07/23 Relatório de Estágio na Área dos Assuntos Regulamentares na Empresa de Consultoria Farmacêutica Pharmaissues
President of the jury
 Beatriz Miguel de Oliveira Mateus (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2021/07/22 Relatório de estágio em coordenação de ensaios clínicos no IPO-Porto
Supervisor
 Inês Leitão (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2021/07/07 Relatório de estágio em Coordenação de Estudos Clínicos no C.H.U.C, E.P.E
Supervisor
 Adriana Mendes (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2021/05/04 Dinamização do Banco de Tumores do IPO Lisboa: a caminho da referência nacional
Supervisor
 Carla Pereira (Master)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2021/02/23 Phosphorylation mediated events in biomarker discovery for Alzheimer´s disease
Supervisor
 Joana Oliveira (PhD)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2021/02/19 Ferramentas e-Health para melhorar o uso de antibióticos
President of the jury
 Érico Fernandes da Silva Carvalho (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2019/12/13 Chemokines effect on kinases and phosphatases involved in AD pathology
Supervisor
 Margarida Vaz (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2019/12/12 The effects of ZnO nanoparticles on male germ cells
President of the jury
 Ana Rita Arede Pinho (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2019/07/18 Analysis of IncRNAs expression in monocytes and osteoclasts of rheumatoid arthritis patients.
Supervisor
 Inês Amaral (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2018/11/14 Characterization of a primary care-based cohort in the Aveiro region of Portugal
(Thesis) Arguer
 Ilka Martins Rosa (PhD)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2018 Study of CD5 and CD6 expression on human iNKT
President of the jury
 Ana Margarida Cunha (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2018 Exosomal proteomes as a source for biomarker discovery in Alzheimer´s disease
Supervisor
 Rui Marçalo (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2018 Studying prostate cancer cell lines metabolome with FTIR spectroscopy
President of the jury
 Francisco Santos (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017/06/12 Characterizing Alzheimer's Amyloid Precursor Protein (APP) neurotrophic functions
(Thesis) Arguer
 Joana Fernandes da Rocha (PhD)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017 Stimulation of a pDC cell line with self-DNA immune complexes
President of the jury
 Daniela Sousa (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017 The relevance of insulin signalling in Alzheimer´s disease
(Thesis) Main arguer
 Steven Ribeiro Alves (Master)
Universidade de Aveiro Departamento de Biologia, Portugal
2017 Cellular response to viral infection: Proteostasis and innate immunity
President of the jury
 Mariana Marques (Master)
Universidade de Aveiro, Portugal
2017 Exosomes as tools for biomarker discovery
Supervisor
 Tânia Martins (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017 Identification of human tRNA modifying enzymes involved in protein aggregation
President of the jury
 Marisa Pereira (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017 Transcriptional and redox changes in Hungtington´s disease human stem cells
President of the jury
 Nuno Piedade (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2017 Mapping UPR elements in male reproductive system
President of the jury
 Andreia Damasceno (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2016 Protein aggregation and proteostasis in aging mice
President of the jury
 Stephany Francisco (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2016 Testing a dementia risk group for polymorphisms in inflammation-related genes
Supervisor
 Sandra Guedes (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2016 Autoimmmune blistering diseases: Bullous Pemphigoid, Pemphigus Vulgaris and Foliaceaus
(Thesis) Main arguer
 Rita Almeida (Master)
Universidade de Aveiro Departamento de Biologia, Portugal
2016 Bin1 molecular studies in a primary care-based cohort
President of the jury
 Maria Cachide (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2015 Optimization of a multielectrode array (MEA)-based approach to study the impact of Abeta on the SH-SY5Y cell line
President of the jury
 José Mateus (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2015 APP RERMS enriched matrix as an adhesion substrate for neuritic outgrowth
President of the jury
 Márcio Costa (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2015 Agentes etiológicos de infeções urinárias em ambulatório
President of the jury
 Hugo Emanuel Vidal (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2015 Association between common lipid metabolism genes polymorphisms and sporadic colorectal adenocarcinoma risk
President of the jury
 Ana Pandeirada (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2015 CD81 interacting proteins
President of the jury
 Soraia Martins (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2015 Saccharomycotin transcriptomics by next-generation sequencing
President of the jury
 Ana Espírito (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2015 Methylglyoxal-induced glycation changes liver lipid content in high-fat diet rats, causing glucose and lipid systemic dysmetabolism
President of the jury
 Christian Neves (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2015 Dissecting the role of adducin in the axonal cytoskeleton
(Thesis) Main arguer
 Joana Rodrigues (Master)
Universidade de Aveiro Departamento de Biologia, Portugal
2015 The impact of Abeta on the Neurabin/PP1 complex
President of the jury
 Helder Alves (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2015 Chemokines impact in Alzheimer´s disease
Supervisor
 Catarina Domingues (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2015 Synergy between antiangiogenic and immunotherapies in breast cancer
President of the jury
 Daniela Ferreira (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2015 Regulation of iron metabolismo in diferente bacterial infections
President of the jury
 Patrícia Ferreira (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2015 Epidemiology of beta-lactamases producing isolates
President of the jury
 Inês Roxo (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2014/05/30 Characterization of novel LAP1 complexes and their relevance in DYT1 dystonia
(Thesis) Arguer
 Mariana Santos Graça (PhD)
Universidade de Aveiro, Portugal
2014 APP is a critical protein in spematogenesis
President of the jury
 Sílvia Silva (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2014 iNKT cells in the metabolic diseases Hemochromatosis and Gaucher´s disease
President of the jury
 Inês Pinheiro (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2014 Analysis of the role of ZP3 and APP proteins in cell-cell adhesion
President of the jury
 Cláudia Busca (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2014 Inflammatory Biomarkers in Alzheimer´s disease
Supervisor
 Cátia Barra (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2013 DNA methylation as a potential biomarker for Alzheimer´s disease
Supervisor
 João Almeida (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2013 The role of Synphilin -1A/PPP1 complex in Lewy bodies formation
President of the jury
 Emanuel Fernandes (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2013 Unraveling the APP/HB-EGF interaction
President of the jury
 Luísa Bastos (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2013 Bioinformatic analysis of the neuronal phosphoproteome
Supervisor
 Marta Cova (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2013 The effects of piezoelectric polymers on neuronal differentiation
President of the jury
 Ana Marote (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2013 Identification of Alzheimer biomarkers by FTIR – a pilot study
Thesis Member
 Rafaela Silva (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2012 Demência e Infertilidade: da bancada para a sociedade
President of the jury
 Daniela Damasceno (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2012 Asma: Estudo da doença no perfil metabolómico da urina
(Thesis) Main arguer
 Ana Oliveira (Master)
Universidade de Aveiro Departamento de Química, Portugal
2012 Establishing stem cell based systems to study neuropathologies
President of the jury
 Sofia Carvalho (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2012 Nuclear Tau function is mediated by protein phosphatase 1 gamma
President of the jury
 Ana Gonçalves (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2012 Demência frontotemporal: diagnóstico molecular em doentes portugueses
President of the jury
 Sandra Peixoto (Master)
Universidade de Aveiro Departamento de Ciências Médicas, Portugal

Conference scientific committee

Conference name Conference host
2023/06/22 - 2023/06/23 2nd Meeting of the Portuguese Network on Extracellular Vesicles (PNEV) Universidade Nova Lisboa
2023/06/16 - 2023/06/17 Workshop on Novel Diagnostic Tools for AD Universidade de Aveiro, Departamento de Ciências Médicas
2011/09/23 - 2011/09/24 Workshop-Neurochemical Diagnostics of Dementia Universidade de Aveiro

Consulting

Activity description Institution / Organization
2017/05/08 - 2017/05/12 Technology transfer in the scope of collaborative research projects at University Medicine Goettingen, Germany.

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2020 - 2024 Biomedical Sciences Degree / Coordination and teaching in the discipline of Human and Cellular Physiology (2020-2024). Teaching in the disciplines of Organic and Functional Systems and/or Biopathology (2020 - 2024). Biomedical Sciences (Licenciatura) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2020 - 2024 Master in Molecular Biomedicine / Coordination and teaching in the discipline of Biomarkers (2020 - 2024). Biomedicine (Mestrado) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2019/10 - 2024 Doctorate in Rehabilitation Sciences / Coordination (2019, 2023) and teaching (2019-2024) in the discipline of Research Methods in Health Sciences. (Doutoramento) Universidade de Aveiro Departamento de Ciências Médicas, Portugal

Universidade de Aveiro Escola Superior de Saúde de Aveiro, Portugal
2018/10 - 2024 Master in Clinical Research Management / Coordination and teaching in the discipline of Biobank and Biological samples management (2018-2024). (Mestrado) Universidade de Aveiro Departamento de Ciências Médicas, Portugal

Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2017/10 - 2022 Doctoral Program in Biomedicine / Coordination and teaching in the Discipline of Aging and Dementia (2017-2022). (Doutoramento) Universidade de Aveiro Departamento de Ciências Médicas, Portugal

Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
2010 - 2020 Master in Molecular Biomedicine / Coordination and/or teaching in the disciplines of Biomarkers, Clinical Pathology and Biomolecular Laboratories II (2010-2020). (Mestrado) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2012/01 - 2019/12 Coordination and/or monitoring of Advanced Experimental Courses for students and teachers of high schools, in the areas of cellular and molecular biology (10 courses of 30h each), from gene to protein (15 courses of 30h each) and neurosciences (11 sessions of 3h each). Collaboration with 'Instituto de Educação e Cidadania da Mamarrosa" (2012-2019). Instituto de Educação e Cidadania da Mamarrosa, Portugal
2009/10 - 2019/03 Biomedical Sciences Degree / Teaching in the disciplines of Clinic Formation, Biopathology, Organic and Functional Systems and From Molecule to Man (2011-2019). Coordination and/or teaching in the disciplines of Molecular Medicine, Biomolecular Laboratories 3 and Human and Molecular Genetics (2009-2011). (Licenciatura) Universidade de Aveiro Departamento de Ciências Médicas, Portugal
2008/10 - 2009/09 Practical disciplines monitor - Bachelor's in Biomedical Sciences Biomedical Sciences (Licenciatura) Universidade de Aveiro Departamento de Ciências Médicas, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2019/05/17 - Current Review Editor on the Editorial Board of Neurodegeneration, part of the journal Frontiers in Neurology, Frontiers in Neuroscience and Frontiers in Psychiatry Frontiers
2021/01/01 - 2022/12/31 Associate editor - Journal of Alzheimer's Disease (1875-8908) IOS Press
2020 - 2021 Reviewer/Referee - Internacional Journal Molecular Sciences (1422-0067) MDPI
2020 - 2020 Reviewer/Referee - Alzheimer's Research & Therapy (1758-9193) Springer Nature
2020 - 2020 Reviewer/Referee - Neurotoxicity Research (1476-3524) Springer
2019 - 2019 Reviewer/Referee - Current Neuropharmacology (1875-6190) Bentham science
2018 - 2018 Reviewer/Referee - Journal of Biological Chemistry (0021-9258) Elsevier
2012 - 2012 Reviewer/Referee - Applied Microbiology and Biotechnology (1432-0614) Springer

Mentoring / Tutoring

Topic Student name
2021/09 - 2024 Tutoria UA Mentoring Program Groups of 7-10 students
2010 - 2024 Tutor in Problem Based-Learning in the Biomedical Sciences degree at UA Groups of 10-12 students
2023/12/18 - 2023/12/20 Mentor of high school students from "Instituto de Educação e Cidadania" da Mamarrosa Group of 4 students
2019/10/01 - 2019/10/31 Tutor in the Project in Design on the Scientific Theme "Alzheimer´s disease" 5 students in the Discipline "Project in Design II" from the degree in Design at UA
2018/10/01 - 2019/01/31 Project Based Learning Supervisor: Blood-derived exosomal miRNA in Alzheimer's disease diagnosis 3 students of the Biomedical Sciences degree at UA

Other jury / evaluation

Activity description Institution / Organization
2021 - 2023 Project evaluator for International Alzheimer´s Association in the funding programs AARF and AARF-D (2021, 2022, 2023). Alzheimer's Association, United States
2022 - 2022 Project evaluator the Fonds National de la Recherche Luxembourg (2022). Fonds National de la Recherche, Luxembourg
Distinctions

Award

2013 BD Bioscience Immunology Research Program (2013). (Prize $10.000 in BD Biosciences reagents).
BD Biosciences, Germany
2004 Travel and registration fellowship from the Conference Organizing Committee to attend the "9th International Conference on Alzheimer´s Disease and Related Disorders"
2004 Fellowship from Fundação Luso-Americana to attend the '9th International Conference on Alzheimer´s Disease and Related Disorders'
Fundação Luso-Americana, Portugal
2004 Fellowship from the Portuguese Society for Neuroscience (SPN) to attend "FENS Forum 2004"
Sociedade Portuguesa de Neurociências, Portugal

Title

2018 Assistant Research (CEECIND/01803/2017)
Fundação para a Ciência e a Tecnologia, Portugal

Other distinction

2022 Top Cited Article 2020-2021: Martins et al. 2020 Journal of Neurochemistry - "Diagnostic and therapeutic potential of exosomes in Alzheimer's disease"
John Wiley & Sons Inc, United States
2019 CELL Guidance Systems Application Note of the article: Martins et. al 2018 PLoS One - 'Exosome isolation from distinct biofluids using precipitation and column-based approaches'
2018 PLoS One Top 10% most cited article: Martins et. al 2018 PLoS One - 'Exosome isolation from distinct biofluids using precipitation and column-based approaches'
2017 Best poster - Rosa I.M., Henriques A.G. and da Cruz e Silva O.A.B. 'Caracterização de Pacientes Hipertensos no Coorte dos Cuidados de Saúde Primária na Região de Aveiro'. (2017)
2009 Journal Cover - Henriques A.G. et al. Journal of Neuroscience Research Vol. 87(6), Maio 2009.
2005 Press release 'EurekAlert October 2005' of the article: Henriques et al. 2005 Journal of Alzheimer's Disease - 'Sodium azide and 2-deoxy-D-glucose-induced cellular stress affects phosphorylation-dependent AbetaPP processing'