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Miguel Maria Varandas Anão Rosado: PhD Candidate | Proteomics & Mass Spectrometry Specialist | Translational Data Analyst Researcher with over seven years of experience in mass spectrometry-based proteomics, combining advanced experimental design (including sample preparation optimization, digestion of complex biological matrices) with robust computational analysis (using statistical programming tools – R/Python) to translate complex datasets into biologically meaningful insights. Skilled in cell culture techniques, including primary neuronal and glial cell cultures, used for in vitro modeling to support translational proteomics research. Additionally proficient in immunocytochemistry techniques and subsequent bio-image analysis using both graphical interface and scripting in ImageJ and QuPath. Member of a reference laboratory of the world leader in mass spectrometry for LC-MS/MS applications, operating at the forefront of Proteomics, Metabolomics and Targeted small molecule analysis. Working under the scientific supervision of Dr. Bruno Manadas, contributing to high-impact analytical workflows and representing a laboratory internationally recognized for methodological excellence and innovation in omics sciences. Currently a PhD student in Experimental Biology and Biomedicine (since 2020) at the Universidade de Coimbra – Instituto de Investigação Interdisciplinar, funded by Fundação para a Ciência e a Tecnologia (2020.07749.BD). Participated as a Research Fellow in 2 projects (POCI-01-0145-FEDER-029311 and REPAIR - PL23-00001). Co-author in two systematic reviews (10.3390/ijms22063142 and 10.1007/s12519-023-00698-7) Master's degree in Pharmaceutical Biotechnology (completed in 2019) by Universidade de Coimbra, Faculdade de Farmácia, resulting in the publication of a book chapter (10.1016/bs.acc.2019.04.003) and a preprint (10.1101/2023.11.23.568435) undergoing peer-reviewed submission. Bachelor's degree in Cellular and Molecular Biology (completed in 2017) by Universidade Nova de Lisboa, Faculdade de Ciências e Tecnologia.
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Identification

Personal identification

Full name
Miguel Maria Varandas Anão Rosado
Date of birth
1995/04/27
Gender
Male

Citation names

  • Rosado, Miguel

Author identifiers

Ciência ID
B219-EE8C-186A
ORCID iD
0000-0002-2727-8868

Email addresses

  • mmva.rosado@gmail.com (Professional)

Telephones

Mobile phone
  • 969314220 (Personal)

Addresses

  • Bairro Alto dos Cucos, Rua Gazeta Eborense, nº 32, 7000-463, Évora, Évora, Portugal (Personal)

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Intermediate (B1) Upper intermediate (B2) Upper intermediate (B2) Advanced (C1)
Education
Degree Classification
2020 - 2026
Ongoing
 Biologia Experimental e Biomedicina (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2023/08
Concluded
 Professional Certificate in Data Analysis for Life Sciences (Outros)
Harvard University T H Chan School of Public Health, United States
2019
Concluded
 Biotecnologia Farmacêutica (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
"A DIFFERENT PERSPECTIVE OF CIRCULATORY BIOMARKERS IN NEURODEGENERATIVE DISEASES: FOCUS ON SERUM HIGH MOLECULAR WEIGHT FRACTION" (THESIS/DISSERTATION)
 18 valores
2017
Concluded
 Biologia Celular e Molecular (Licenciatura)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
 14 valores
Projects

Grant

Designation Funders
2025/04/24 - 2026/04/23 REPAIR - Reparar e Recuperar no AVC isquémico: novas estratégias de terapia celular
PL23-00001
Research Fellow
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
Ongoing
2021/01/01 - 2024/12/31 A different perspective in translational research: from secretome to peripheral biomarkers of hypoxic-ischemic encephalopathy
2020.07749.BD
PhD Student Fellow
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2020/03/01 - 2020/12/31 Novas abordagens em Encefalopatia hipóxico-isquémica: investigação translacional para diagnosticar e monitorizar resposta a terapia com células estaminais
POCI-01-0145-FEDER-029311
Research Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Rosado, Miguel; Silva, Rafael; G. Bexiga, Mariana; G. Jones, John; Manadas, Bruno; Anjo, Sandra I.. "Advances in biomarker detection: Alternative approaches for blood-based biomarker detection". In Advances in Clinical Chemistry, 141-199. Elsevier, 2019.
    Published • 10.1016/bs.acc.2019.04.003
Conference poster
  1. Rosado, Miguel; Empadinhas, Catarina Morais; Santos, Vitor; Cátia Santa; Grãos, Mário; Coroa, Manuel; Morais, Sofia; et al. Corresponding author: MANADAS, BRUNO. "Cytokine plasma profiling as a potential predictor of clinical stage transition in first-episode psychosis". Paper presented in BEB DAY 2025 - From Micor-Scales to Macro-Worlds: Transcending the Limits of Science, 2025.
  2. Rosado, Miguel; Empadinhas, Catarina; Santos, Vitor; Cátia Santa; Grãos, Mário; Coroa, Manuel; Morais, Sofia; et al. Corresponding author: MANADAS, BRUNO. "Cytokine plasma profiling as a potential predictor of clinical stage transition in first-episode psychosis". Paper presented in V Metabolism, Aging & Disease Meeting - 5th CiBB retreat, 2025.
  3. Sandra I. Anjo; Rosado, Miguel; Baldeiras, Ines; Andreia Gomes;  Diana Pires; Cátia Santa; Joana Pinto; et al. Corresponding author: MANADAS, BRUNO. "Unmasking hidden systemic effects in the serum proteome of neurodegenerative diseases: a double approach protocol applied to peripheral biomarker discovery". Paper presented in  Congresso de Neurologia -  Hot Topics 2023, 2023.
  4. Sandra I. Anjo; Rosado, Miguel; Baldeiras, Ines; Andreia Gomes; Diana Pires; Cátia Santa; Joana Pinto; et al. Corresponding author: MANADAS, BRUNO. "Unmasking hidden systemic effects in the serum proteome of neurodegenerative diseases: a double approach protocol applied to peripheral biomarker discovery". Paper presented in EMBL - Wellcome Connecting Science Conference: Proteomics in cell biology and disease mechanisms, 2023.
  5. Sandra I. Anjo; Rosado, Miguel; Baldeiras, Ines; Andreia Gomes;  Diana Pires; Cátia Santa; Joana Pinto; et al. Corresponding author: MANADAS, BRUNO. "Unmasking Hidden Systemic Effects of Neurodegenerative Diseases: A Double Approach protocol applied to Serum Biomarker Discovery". Paper presented in CONGRESSO SPDMOV 2023, 2023.
Journal article
  1. Tessa M. Page; Miguel Rosado; Vera M. Mendes; Ella Guscelli; Joana Filipa Fernandes; Denis Chabot; Ricardo Calado; et al. "Northern shrimp exhibit origin-specific proteomic remodelling under ocean acidification, with limited response to ocean warming". Marine Pollution Bulletin (2026): http://dx.doi.org/10.1016/j.marpolbul.2025.119152.
    10.1016/j.marpolbul.2025.119152
  2. Inês Caramelo; Margarida Coelho; Miguel Rosado; Carla M. P. Cardoso; Alexandra Dinis; Carlos B. Duarte; Mário Grãos; Bruno Manadas. "Biomarkers of hypoxic–ischemic encephalopathy: a systematic review". World Journal of Pediatrics (2023): http://dx.doi.org/10.1007/s12519-023-00698-7.
    10.1007/s12519-023-00698-7
  3. Inês Serrenho; Miguel Rosado; Alexandra Dinis; Carla M. Cardoso; Mário Grãos; Bruno Manadas; Graça Baltazar. "Stem Cell Therapy for Neonatal Hypoxic-Ischemic Encephalopathy: A Systematic Review of Preclinical Studies". International Journal of Molecular Sciences 22 6 (2021): 3142-3142. https://doi.org/10.3390/ijms22063142.
    10.3390/ijms22063142
Preprint
  1. Miguel Rosado; Catarina Empadinhas; Vitor Santos; Catia Santa; Mario Graos; Manuel Coroa; Sofia Morais; et al. "IL-17A, IFN-¿, and MIP-3a Plasma Profiles Predict Clinical Stage Transition in First-Episode Psychosis". 2026. https://doi.org/10.64898/2026.02.17.26346145.
    10.64898/2026.02.17.26346145
  2. Sandra I. Anjo; Miguel Rosado; Inês Baldeiras; Andreia Gomes; Diana Pires; Cátia Santa; Joana Pinto; et al. "Unmasking Hidden Systemic Effects of Neurodegenerative Diseases: A Two-Pronged Approach to Biomarker Discovery". 2023. https://doi.org/10.1101/2023.11.23.568435.
    10.1101/2023.11.23.568435
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2026/05/22 Are your replicates independent? Defining experimental units in primary neuron proteomics ProteoVilamoura - 6th Joint Meeting of Spanish, French and Portuguese Proteomics Societies
Portuguese Association of Proteomics- REDE PROCURA (Vilamoura, Portugal)

Event organisation

Event name
Type of event (Role)		 Institution / Organization
2026/05/20 - 2026/05/22 ProteoVilamoura - 6th Joint Meeting of the Portuguese, Spanish and French Proteomics Societies (2026/05/20 - 2026/05/22)
Conference (Other)
 Portuguese Association of Proteomics- REDE PROCURA, Portugal
2025/06/27 - 2025/06/27 Event focusing on oxygen physiology and advanced respirometry technologies applied to biomedical research. (2025/06/27 - 2025/06/27)
Workshop (Other)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Event participation

Activity description
Type of event		 Event name
Institution / Organization
2025/12/29 - 2025/12/29 Fundamental data skills with an online course that teaches how to analyze, manage, and visualize data.
Workshop
 DavidsonX.D006: Essentials of Data Literacy
Davidson College, United States
2025/05/05 - 2025/05/09 Proteomics Course
Workshop
 Advanced Course: Proteomics Approaches in Life Sciences
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2024/12/09 - 2024/12/13 Machine Learning for Biomedicine Research and Healthcare: From Theory to Practice
Workshop
 Machine Learning for Biomedicine Research and Healthcare: From Theory to Practice
Universidade de Coimbra Multidisciplinary Institute of Ageing, Portugal
2024/10/14 - 2024/10/18 GENERALISED LINEAR MIXED MODELS IN R
Workshop
 GENERALISED LINEAR MIXED MODELS IN R
Physalia Courses, Germany
2022/11 - 2022/11 Data visualization in R with ggplot2
Workshop
 Data visualization in R with ggplot2
Physalia Courses, Germany

Mentoring / Tutoring

Topic Student name
2024/07 - 2025/10 Diagnosis and treatment of hypoxic-ischemic neonatal encephalopathy. Cellular models and stem cells therapy Beatriz Maurício
2025/02 - 2025/03 The sepsis phenotype in a paediatric patient with septic shock Inês Henriques
2023/02/26 - 2023/03/22 Lab Rotation - Comparing different sample preparation methods for plasma proteomics Guilherme Rolo
2021 - 2022 Plasma proteomics screening of neuropsychiatric disorders Bárbara da Rocha Henriques
Distinctions

Award

2024 Honourable Mention - Oral Communication, at BEBDay 2024