Identification
Personal identification
- Full name
- Sofia Baptista de Carvalho
Citation names
- Carvalho, Sofia B.
Author identifiers
- Ciência ID
- B212-8A9B-233B
- ORCID iD
- 0000-0001-5000-7217
- Google Scholar ID
- TdHAxzkAAAAJ
Email addresses
- sofiacarvalho@ibet.pt (Professional)
Telephones
- Telephone
-
- (+351) 214469448 Ext.: 1448 (Professional)
Addresses
- iBET. Av. da República, Estação Agronómica Nacional, 2780-157, Oeiras, Oeiras, Portugal (Professional)
Knowledge fields
- Natural sciences - Biological Sciences - Biochemistry
- Natural sciences - Biological Sciences - Biochemical Research Methods
- Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology
- Engineering and Technology - Industrial Biotechnology - Bioprocessing Technologies
- Medical and Health Sciences - Medical Biotechnology - Technologies Involving the Manipulation of Cells, Tissues, Organs or the Whole Organism
Languages
Language | Speaking | Reading | Writing | Listening | Peer-review |
---|---|---|---|---|---|
English | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) | Proficiency (C2) |
Portuguese (Mother tongue) |
Education
Degree | Classification | |
---|---|---|
2018/12/14
Concluded
|
Technological and Engineering Sciences (Doutoramento)
Major in Biotechnology
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
"Downstream strategies for VLPs as candidate universal vaccine for Influenza" (THESIS/DISSERTATION)
|
Approved by Unanimity |
2013/06/03
Concluded
|
Estágio de Investigação Científica A (60 ECTS) (Pós-Graduação)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
18 |
2011/10/19
Concluded
|
Bioquímica (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Structural and conformational effects of metal binding to the S100B cytokine" (THESIS/DISSERTATION)
|
17 |
2009/07/15
Concluded
|
Bioquímica (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
|
14 |
Affiliation
Science
Category Host institution |
Employer | |
---|---|---|
2018/09/15 - Current | Contracted Researcher (Research) | Instituto de Biologia Experimental e Tecnológica, Portugal |
Instituto de Biologia Experimental e Tecnológica, Portugal | ||
2014/01/01 - 2017/02/28 | Researcher (Research) | Instituto de Biologia Experimental e Tecnológica, Portugal |
2010/02/01 - 2011/10/01 | Research Trainee (Research) | Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
Others
Category Host institution |
Employer | |
---|---|---|
2018/01/01 - 2018/08/31 | Project Manager | GenIBET Biopharmaceuticals, Portugal |
2014/01/01 - 2017/02/28 | PhD Student | Instituto de Biologia Experimental e Tecnológica, Portugal |
2016/09/17 - 2016/12/17 | Visiting PhD Student | Max-Planck-Institut fur Dynamik komplexer technischer Systeme, Germany |
2015/06/01 - 2015/06/15 | Visiting PhD Student | PALL Life Sciences , United Kingdom |
2013/04/01 - 2014/02/28 | BI Researcher | Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
2011/09/01 - 2013/06/03 | Post-Graduation: Scientific Research Training A (Grade 18/20 - 60ECTS) | Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
2012/04/01 - 2013/03/31 | BI Researcher | Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
2012/01/15 - 2012/01/25 | Visiting Research Student | Institut Européen de Chimie et Biologie, France |
2010/09/01 - 2011/10/11 | Master Student | Universidade de Lisboa Faculdade de Ciências, Portugal |
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal | ||
2008/02/03 - 2009/06/30 | Undergraduate research trainee | Instituto Nacional de Medicina Legal e Ciências Forenses Delegação do Sul, Portugal |
Projects
Grant
Designation | Funders | |
---|---|---|
2012 - 2012 | Studies on human S100 protein-aptamer complexes
n/a
Visiting researcher
|
European Comission
Concluded
|
Contract
Designation | Funders | |
---|---|---|
2024/06/17 - 2026 | Advanced bioanalytic solutions to support CAR-based products development and manufacturing challenges: from viral vectors
to CAR-expressing cells
PI778
Principal investigator
Instituto de Biologia Experimental e Tecnológica, Portugal
|
Instituto de Biologia Experimental e Tecnológica
Ongoing
|
2025/01/01 - 2025/12/31 | Integrando Produção e Purificação Contínuas para Alavancar a Manufactura de Vírus Adeno-Associados Recombinantes (rAAV)
2023.15456.PEX
Researcher
Instituto de Biologia Experimental e Tecnológica, Portugal
|
Fundação para a Ciência e a Tecnologia
Ongoing
|
2021/03/15 - 2024/10/01 | Ultrapassar os desafios de produção de virus adeno-associados no tratamento de distrofia muscular.
PTDC/BTM-ORG/1383/2020
Researcher
Instituto de Biologia Experimental e Tecnológica, Portugal
iNOVA4Health, Portugal FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal Universidade de Lisboa Centro de Ecologia Evolução e Alterações Ambientais, Portugal |
Fundação para a Ciência e a Tecnologia
Concluded
|
2022/01/01 - 2023/12/31 | Bioanalytics for misparing profiling of multispecific antibodies: impact on bioprocess design
PI754
Principal investigator
Instituto de Biologia Experimental e Tecnológica, Portugal
|
Instituto de Biologia Experimental e Tecnológica
Concluded
|
2014/01/01 - 2017/12/31 | EDUFLUVAC EDUcate InFLUenza VACcine
602640
PhD Student Fellow
Instituto de Biologia Experimental e Tecnológica, Portugal
|
European Comission
Concluded
|
2012 - 2014 | Mechanisms of SOD1 toxic aggregation in neurodegenerative processes
PTDC/QUI-BIQ/117789/2010
Research Fellow
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
2011 - 2014 | Amyloidogenesis of the S100A8/A9 cytokine as an anti-proliferative mechanism in prostate cancer
n/a
Research Fellow
|
Liga Portuguesa Contra o Cancro
Concluded
|
2012 - 2013 | Recovery of misfolded and aggregated proteins using biological nanoreactors and small molecules
PTDC/EBB-BIO/117793/2010
Research Fellow
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluded
|
Outputs
Publications
Book chapter |
|
Conference abstract |
|
Conference paper |
|
Conference poster |
|
Journal article |
|
Activities
Oral presentation
Presentation title | Event name Host (Event location) |
|
---|---|---|
2024/06/23 | Unveiling mAbs & viral vectors´ attributes by Mass Spectrometry-based advanced bioanalytics | 28th ESACT Meeting 2024
(Edimburgo, United Kingdom)
|
2024/05/22 | Understanding AAV Impurities and Product Attributes through Advanced Bioanalytics for Bioprocess Characterization | Gene therapy analytical development Europe
(Londres, United Kingdom)
|
2024/05/11 | Characterization of mAbs attributes and HCP clearance by advanced Mass Spectrometry-based bioanalytics | 16th Annual PEGS Europe
(Barcelona, Spain)
|
2023/04/04 | Advances in Bioanalytical Tools for the Characterization of In-Process Viral Samples | BioProcess International - ask the expert Webinar
(Online)
|
2022/06/26 | Bioanalytical tools for characterization of process samples of a rotavirus vaccine | ACTIP workshop @ESACT 2022
(Lisboa)
|
2021/09/01 | Advances in Analytics for Gene Therapy and Vaccines | STACCATO 3rd Industry-Academia Network Training Experience
(Online)
|
2021/05/01 | Advances in Analytics to Streamline the Production of Viruses for Gene Therapy and Vaccination | Gene Therapy Analytical Development Europe
(Online)
|
2017 | New tools for Influenza Virus-like particles bioprocess optimization | 8th ITQB NOVA PhD Students Meeting
ITQB (Oeiras, Portugal)
|
2017 | Challenges in influenza virus-like particles production: New analytical tools and downstream process optimization | Influenza Vaccines for the World
(Lausanne, Switzerland)
|
2016 | Universal and in-process influenza virus-like particles quantification tool using Octet technology | PALL Forté Bio User Meeting - Protein Analysis & Characterization Workshop, Lyon, France
(Lyon)
|
2016 | Monitoring and improving Influenza Virus-Like particles Downstream Processing using a click chemistry approach | ISPPP
(Salzburg, Austria)
|
2016 | Universal label-free in-process analytical tool for Influenza virus-like particles quantification | Virus-like particle & Nano-particle vaccines
(Leiden, Netherlands)
|
2016 | Universal and in-process analytical tool for Influenza quantification using a label-free technology | Vaccine Technology VI Conference
(Albufeira, Portugal)
|
2015 | A click chemistry approach to monitor and improve Influenza VLPs Downstream Processing | Affinity 2015 - 21st Biennial Meeting of the International Society for Molecular Recognition
(Puerto Vallarta, Mexico)
|
Event organisation
Event name Type of event (Role) |
Institution / Organization | |
---|---|---|
2015 - 2015 | Biotech World Tour: an innitiative that increases the impact and visibility of biotechnology among youth and the general public
through hands-on and discussion-led learning opportunities (2015 - 2015)
Exhibition (Other)
|
|
2014/03/01 - 2014/11/07 | 5th ITQB PhD Students’ Meeting (2014/11/06 - 2014/11/07)
Conference (Member of the Organising Committee)
|
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal |
Event participation
Activity description Type of event |
Event name Institution / Organization |
|
---|---|---|
2022/09/12 - 2022/09/16 | Proteomics Data Analysis Course
Other
|
Instituto Gulbenkian de Ciência, Portugal
|
2019/11/01 - 2019/11/02 | Design of Experiments - Sartorius Stedim Data Analytics AB Course
Other
|
Instituto de Biologia Experimental e Tecnológica, Portugal
|
2019/07/03 - 2019/07/05 | Prince2 Foundation in Project Management (21h, Axelos/PeopleCert)
Workshop
|
|
2014/10/06 - 2014/10/12 | ISBio Course on Integrative Structural Biology tools for the study of protein-ligand interactions
Workshop
|
ISBio – Course on Integrative Structural Biology tools for the study of protein-ligand interactions
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
|
2014/09/28 - 2014/10/02 | Animal Cell Technology Course, 4th Edition - ESACT - Llafranc, Spain
Workshop
|
|
2013 - 2013 | MicroCal Course Advanced Isothermal Titration Calorimetry, GE Healthcare Training Couse
Workshop
|
MicroCal Course – Advanced Isothermal Titration Calorimetry
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
2010/10/08 - 2010/10/10 | Short Course in Protein folding, misfolding and disease
Workshop
|
Short Course in “Protein folding, misfolding and disease”
Sociedade Portuguesa de Biofísica, Portugal
|
Journal scientific committee
Journal title (ISSN) | Publisher | |
---|---|---|
2024/01/25 - Current | Applied Microbiology and Biotechnology (0175-7598) | Springer |
2023/08/25 - Current | Journal of Biotechnology (0168-1656) | Elsevier |
2020 - Current | Cell and Gene Therapy Insights | Bioprocess International |
2018 - Current | Vaccine | Elsevier |
Mentoring / Tutoring
Topic | Student name | |
---|---|---|
2016 - 2017 | MSc Thesis: Downstream process development of novel valuable bio-therapeutics | Ana Sofia Moreira |
2015 - 2016 | MSc Thesis: Exploring novel downstream strategies for the purification of enveloped VLPs | Mafalda Sofia Gameiro Moleirinho |
Distinctions
Award
2016 | Best poster (3rd prize) at PREP - Preparative and Process Chromatography Conference |
2015 | Young Investigator Award at Affinity 2015 - 21st Biennial Meeting of the International Society for Molecular Recognition |
Other distinction
2017 | Travel and accommodation Grant to participate on Single-Use Technologies II: Bridging Polymer Science to Biotechnology Applications
Conference
Engineering Conferences International, United States
|
2016 | Travel and accommodation Grant to participate on Vaccine Technology VI Conference
Engineering Conferences International, United States
|
2016 | Travel and accommodation Grant to participate on ISPPP Symposium |
2016 | Short-term (2 months) fellowship at Max Planck Institute for Dynamics of Complex Technical Systems
Fundação para a Ciência e a Tecnologia, Portugal
|
2013 | BI Research Fellowship |
2013 | PhD Fellowship: Molecular Biosciences PhD Program
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
|
2012 | BI Research Fellowship under the project Mechanisms of SOD1 toxic aggregation in neurodegenerative processes |
2012 | Travel Grant to IECB, Bordeaux, France - Visiting Research Student |