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I am a student in the Cardiovascular Science PhD Program at the Faculty of Medicine, University of Porto. My doctoral research takes place in the Cardiovascular Research and Development Centre (UnIC) and aims to study the microbiome of patients with severe aortic stenosis (AS). I am graduated in Biology from the University of Aveiro since 2015, and I hold an MSc in Cell and Molecular Biology from the Faculty of Science of the University of Porto since 2017.
Identification

Personal identification

Full name
Diana Luísa Ferreira Martins

Author identifiers

Ciência ID
B116-6180-2685

Websites

Education
Degree Classification
2021/10 - 2025
Ongoing
 Doctoral Program in Cardiovascular Sciences (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
2023/11 - 2024/04
Concluded
 Microbiome data analysis (Outros)
Institute of Medical Microbiology and Hygiene, University Medical Center of the Johannes Gutenberg University Mainz, Germany
2020/10 - 2021/07
Attended
 Doctoral Program in Biomedicine (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
2018/02/19 - 2018/02/23
Attended
 1st Theoretical-Practical Course in Cytogenetics and Genomics in Diagnosis and Research (Outros)
Universidade de Coimbra - Faculdade de Medicina, Portugal
2015/09/21 - 2017/11/29
Concluded
 Master in Cellular and Molecular Biology (Mestrado)
Universidade do Porto Faculdade de Ciências, Portugal
"Fabry disease associated with GLA p.Phe113Leu variant for a common ancestor in Portuguese and Italians, and use of linked markers to estimate the age of the mutation" (THESIS/DISSERTATION)
 17
2012/09/11 - 2015/07/14
Concluded
 Bachelor's degree in Biology (Licenciatura)
Universidade de Aveiro, Portugal
"Effects of 4-MBC and triclosan in embryos of the frog Pelophylax perezi" (THESIS/DISSERTATION)
 15
2015/05 - 2015/06
Attended
 8th Course in Forensic Sciences (Outros)
Universidade de Aveiro, Portugal
2014/09/22 - 2014/12/18
Attended
 Language Courses - English (Outros)
Universidade de Aveiro Departamento de Línguas e Culturas, Portugal
Affiliation

Others

Category
Host institution 		Employer
2019/10/01 - 2021/12 Research Grant - UID/IC/00051/2019 Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
2018/04/01 - 2019/08/31 Research Grant - PTDC/BBB-BIO/0508/2014 Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
Projects

Contract

Designation Funders
2018/04/04 - 2019/08/31 Overcoming the Brain Drug Delivery Bottleneck: Development of single domain antibodies for brain targeting and drug delivery across the Blood Brain Barrier
PTDC/BBBBIO/0508/2014
Research Fellow
Universidade de Lisboa Faculdade de Medicina Veterinária, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Conference abstract
  1. Ana Beatriz Batista; Martins, Diana; Juliana Ferreira; Joana Pinto; António Carlos Ferreira; Claúdia Silva; Paulo Castro-Chaves; et al. "Neurologic deficit and functional independence after stroke: an exploratory analysis of urine and plasma metabolomics". Paper presented in Congresso SPCCTV 2023, Albufeira, 2023.
Conference poster
  1. Martins, Diana; Ana Beatriz Batista; Javier Centelles Lodeiro; Sílvia O. Diaz; Juliana Ferreira; Claudia Silva; António Carlos Ferreira; et al. "Impact of gut microbiome on functional recovery in stroke patients". Paper presented in 2nd Conference of the Doctoral Program in Metabolism - Clinical and Experimental (MET-CONF 2024), 2024.
  2. Grego, Ana; Sousa-Mendes, Cláudia; Martins, Diana; Sousa, Carla; Ferreira, Ana Filipa; Saraiva, Francisca ; Miranda, Isabel; et al. Corresponding author: Trindade, Fábio. "Sex Disparities in Aortic Valve Stenosis: from the histological to the molecular level". Paper presented in VII iBiMED Symposium, 2024.
  3. Aguiar, Sandra I; Silva, Marta; Martins, Diana; André, Ana S.; Neves, Vera; Dias, Joana NR; Carrapiço, Belmira; et al. "Overcoming the BBB: in vivo selection of single domain antibodies for brain targeting and drug delivery". Paper presented in 11th Annual PEGS EUROPE 18-22th November 2019, Lisbon, Portugal, 2019.
  4. Martins, Diana; Aguiar, Sandra; André, Ana; Dias, Joana; Carrapiço, Belmira; Gano, Lurdes; Galamba, João; et al. "In Vivo Phage Display Selections for Development of Novel Blood Brain Barrier Crossing Single Domain Antibodies". Paper presented in 10th Annual PEGS Summit Europe, 2019.
  5. Martins, Diana; Ferreira, Susana; Oliveira, João Paulo; Pereira, Luísa; Chiesa, Nicoletta. "GLA p.Phe113Leu variant: Evidence for a common ancestor between Portuguese and Italians". Paper presented in 22ª Reunião Anual da Sociedade Portuguesa de Genética Humana (SPGH), 2019.
  6. Aguiar, Sandra I; Gaspar, Maria Manuela; André, Ana; Martins, Diana; Ferreira, Marta; Carvalheiro, Manuela; Neves, Vera; et al. "sdAb-immunoliposomes for brain targeting and drug delivery.". Paper presented in PEGS Europe, 2018.
Journal article
  1. Marta Borges-Canha; Javier Centelles-Lodeiro; Ana Rita Leite; Joana Chaves; Inês Mariana Lourenço; Madalena Von-Hafe; Catarina Vale; et al. "Gut dysbiosis is linked to severe steatosis and enhances its diagnostic performance in Metabolic Dysfunction-Associated Steatotic Liver Disease". eGastroenterology (2025):
    Submitted
  2. Alexandre Gonçalves; Inês N Alves; Cláudia Sousa-Mendes; Daniela Miranda-Silva; Glória Conceição; João Almeida-Coelho; Martins, Diana; et al. Corresponding author: Inês Falcão-Pires. "Ketogenic diet and ketone salts differentially improve cardiometabolic complications in a HFpEF rat model". The Journal of Physiology (2025):
    Accepted
  3. Marta Borges Canha; Ana Rita Leite; Glória Conceição; Catarina Vale; Madalena Von-Hafe; Martins, Diana; Daniela Miranda-Silva; et al. Corresponding author: Marta Borges Canha. "Evaluation of the hepatic and subcutaneous adipose tissue effects of triiodothyronine treatment in an animal model of metabolic syndrome". Diabetes & Metabolic Syndrome: Clinical Research & Reviews (2024):
    Submitted
  4. Ana Grego; Cláudia Sousa-Mendes; Martins, Diana; Carla Sousa; Ana Filipa Ferreira; Francisca Saraiva; Inês Alves; et al. "Dissecting Sexual Dimorphism in Aortic Valve Stenosis by Proteomics". Atherosclerosis Journal 395 (2024):
    Accepted
  5. Diana Martins; Cláudia Silva; António Carlos Ferreira; Sara Dourado; Ana Rita Nunes Albuquerque; Francisca Saraiva; Ana Beatriz Batista; et al. "Unravelling the Gut Microbiome Role in Cardiovascular Disease: A Systematic Review and a Meta-Analysis". Biomolecules (2024): https://www.mdpi.com/2218-273X/14/6/731.
    10.3390/biom14060731
  6. Rita Teixeira; Cláudia Silva; António Carlos Ferreira; Diana Martins; Leite-Moreira, AF; Isabel M Miranda; António S. Barros. "The Association between Gestational Diabetes and the Microbiome: A Systematic Review and Meta-Analysis". Microorganisms (2023): https://www.mdpi.com/2076-2607/11/7/1749.
    10.3390/microorganisms11071749
  7. Neves, João Sérgio; Leite, Ana Rita; Conceição, Glória; Gonçalves, Alexandre; Borges-Canha, Marta; Vale, Catarina; Von-Hafe, Madalena; et al. "Effects of Triiodothyronine Treatment in an Animal Model of Heart Failure with Preserved Ejection Fraction". Thyroid (2023): http://dx.doi.org/10.1089/thy.2022.0717.
    10.1089/thy.2022.0717
  8. Trindade, Fábio; Ana F. Ferreira; Francisca Saraiva; Martins, Diana; Vera M. Mendes; Carla Sousa; Cristina Gavina; et al. "Optimization of a Protocol for Protein Extraction from Calcified Aortic Valves for Proteomics Applications: Development of a Standard Operating Procedure.". Proteomes 10 3 (2022): 30. https://doi.org/10.3390/proteomes10030030.
    Published
  9. Sandra Isabel Aguiar; Joana N. R. Dias; Ana André; Marta Lisete Silva; Diana Martins; Belmira Carrapiço; Miguel Castanho; et al. "Highly Specific Blood-Brain Barrier Transmigrating Single-Domain Antibodies Selected by an In Vivo Phage Display Screening". Pharmaceutics (2021): https://www.mdpi.com/1999-4923/13/10/1598.
    10.3390/pharmaceutics13101598
  10. Mariana Fragão-Marques; Isaac Barroso; Rui Farinha; Isabel M Miranda; Diana Martins; Jennifer Mancio; João Rocha-Neves; et al. "Pericardial NT-Pro-BNP and GDF-15 as Biomarkers of Atrial Fibrillation and Atrial Matrix Remodeling in Aortic Stenosis". Diagnostics (2021): https://www.mdpi.com/2075-4418/11/8/1422.
    10.3390/diagnostics11081422
  11. Conceição, Glória; Martins, Diana; M. Miranda, Isabel; Leite-Moreira, Adelino F.; Vitorino, Rui; Falcão-Pires, Inês. "Unraveling the Role of Epicardial Adipose Tissue in Coronary Artery Disease: Partners in Crime?". International Journal of Molecular Sciences 21 22 (2020): 8866. http://dx.doi.org/10.3390/ijms21228866.
    Open access • 10.3390/ijms21228866
  12. Fragão-Marques, Mariana; Miranda, I.; Martins, D.; Barroso, I.; Mendes, C.; Pereira-Neves, A.; Falcão-Pires, I.; Leite-Moreira, A.. "Atrial matrix remodeling in atrial fibrillation patients with aortic stenosis". BMC Cardiovascular Disorders 20 1 (2020): 468. http://dx.doi.org/10.1186/s12872-020-01754-0.
    Open access • Published • 10.1186/s12872-020-01754-0
  13. Martins, Diana; Monteiro, Marta S.; Soares, Amadeu M.V.M.; Quintaneiro, Carla. "Effects of 4-MBC and triclosan in embryos of the frog Pelophylax perezi". Chemosphere 178 (2017): 325-332. http://dx.doi.org/10.1016/j.chemosphere.2017.03.038.
    Published • 10.1016/j.chemosphere.2017.03.038
Thesis / Dissertation
  1. Martins, Diana. "Fabry disease associated with GLA p.Phe113Leu variant for a common ancestor in Portuguese and Italians, and use of linked markers to estimate the age of the mutation". Master, Universidade do Porto Faculdade de Ciências, 2015.
Activities

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2024/10/23 - 2024/10/23 RISE Day (PT: Rede de Investigação em Saúde)
Meeting
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
2024/07/03 - 2024/07/05 Science Meeting 2024 (PT: Encontro Ciência 2024)
Meeting
Fundação para a Ciência e a Tecnologia, Portugal
2023/04/20 - 2023/04/23 20th Exhibition of the University of Porto (PT: Mostra U.Porto 2023)
Exhibition
Universidade do Porto, Portugal
2022/04/21 - 2022/04/24 19th Exhibition of the University of Porto (PT: Mostra U.Porto 2022)
Exhibition
Universidade do Porto Faculdade de Medicina, Portugal
Distinctions

Award

2024 Award Professor Américo Carvalhinhos: Best Work presented "Microbial Markers in Gastric Cancer: The Microbiota as a Tool for Early Diagnosis"
Núcleo de Neurogastrenterologia e Motilidade Digestiva, Portugal

Other distinction

2024 Honorable Mention for Poster "Impact of gut microbiome on functional recovery in stroke patients"
Universidade do Porto Faculdade de Medicina, Portugal