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Identification

Personal identification

Full name
Nilza Maria Lopes Ribeiro

Citation names

  • Ribeiro, Nilza

Author identifiers

Ciência ID
AF1C-680D-27F0

Languages

Language Speaking Reading Writing Listening Peer-review
English Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
French Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2016
Concluded
 PhD in Biomedical Engineering (Doutoramento)
Universidade do Porto Faculdade de Engenharia, Portugal
"SPARC grafted on a 3D synthetic model (collagen/nanohydroxyapatite) and its effect on bone regeneration and cancer related bone metastasis" (THESIS/DISSERTATION)
 Aprovado Unanimidade
2009
Concluded
 Master in Biomedical Engineering (Mestrado)
Universidade do Porto Faculdade de Engenharia, Portugal
"Fibronectin and Osteonectin Adsorption onto Hydroxyapatite Nanostructures and its Influence on Osteoblast Adhesion" (THESIS/DISSERTATION)
 16
2001
Concluded
 Graduation in Biochemistry (field of specialization – Applied Biochemistry) (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"Apoptose nas células do córtex supra-renal do rato durante o envelhecimento" (THESIS/DISSERTATION)
 12
Affiliation

Others

Category
Host institution 		Employer
2022/03/01 - Current Post-Doc researcher (first level) in the scope of the Interlynk project “Human Platelet Lysates-based Scaffolds for Interfacial Multi-tissue Repair” ref. 953169 Universidade de Aveiro, Portugal
Universidade de Aveiro Departamento de Engenharia de Materiais e Cerâmica, Portugal
2019/08/16 - 2022/02/15 Post-Doc researcher (first level) in the scope of the 2BBone project “Desenvolvimento de biomateriais não sinterizáveis à base de fosfatos de cálcio com bi-funcionalidade: regeneração e tratamento de Universidade de Aveiro, Portugal
Universidade de Aveiro Departamento de Engenharia de Materiais e Cerâmica, Portugal
2018/01/01 - 2019/08/15 Post-Doc researcher in CBQF with a Post-doctoral Fellowship in the scope of the Project "IBEROS” (0245_IBEROS_1_E), funded by Fundo Europeu de Desenvolvimento(POCTEP) 2014-2020.. Portuguesa Centro de Biotecnologia e Química Fina, Portugal
Universidade Católica Portuguesa Centro Regional do Porto, Portugal
2019/01 - 2019/05 Program Newfood and FoodValorization, Faculty of Biotechnology/UCP Portugal, January 2019 – May 2019. Universidade Católica Portuguesa Centro Regional do Porto, Portugal
2017/10 - 2018/01 Program Biotech agrifood innovation 2nd edition for pre-acceleration of business projects, Faculty of Biotechnology/UCP Portugal Universidade Católica Portuguesa Centro Regional do Porto, Portugal
2017/03/01 - 2017/12/31 Post-Doc Researcher in the Biocomposites group of I3S with a Post-doctoral Fellowship in the scope of the Project Structured Program NORTE-01- 0145-FEDER-000012. Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017/09/11 - 2017/09/22 Course in Laboratory Animal Science accredited by FELASA (accreditation number 020/08) Category C, organized by the Laboratory Animal Science group – IBMC and held at i3S, Porto. Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2017/08/01 - 2017/08/28 Advanced training at Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas, USA, under supervision of Prof. Rolf Brekken in the scope of the F University of Texas Southwestern Medical School, United States
2015/06/01 - 2016/02/29 Research Technician, at iinfacts laboratory from CESPU (Cooperativa de Ensino Superior Politécnico e Universitário, CRL) Cooperativa de Ensino Superior Politécnico e Universitário, Portugal
2012/02/18 - 2015/07/14 Program COHiTEC 2015/COTEC Portugal, Training program in technology commercialization for researchers, Porto Business School. Universidade do Porto Porto Business School, Portugal
2009/09/01 - 2015/06/30 PhD student in Biomedical Engineering, FEUP with a scholarship from the Portuguese Foundation for Science and Technology (FCT), ref. SFRH/BD/69686/2010 Universidade do Porto Faculdade de Engenharia, Portugal
2009/09/01 - 2012/08/31 Team member on the project NANOFORBONE, ADI-Agência de Inovação, ref. SI IDT - 5372/2008, INEB- Instituto de Engenharia Biomédica, Universidade do Porto. Instituto Nacional de Engenharia Biomédica, Portugal
2012/01/02 - 2012/03/29 Advanced training at MIRA University of Twente, Enschede, The Netherlands, under supervision of Dr. Lorenzo Moroni, in order to obtain specialized training in the technique of "electrospinning" Universiteit Twente, Netherlands
2011/06/17 - 2011/10/21 Nanotechnology and nanomedicine course, INL International Iberian Nanotechnology Laboratory, Portugal
2007/09/01 - 2009/09/15 MSc student in Biomedical Engineering, FEUP. Universidade do Porto Faculdade de Engenharia, Portugal
2007/03/01 - 2008/09/30 Researcher at IBMC- Instituto de Biologia Molecular e Celular, Universidade do Porto, under the Program “Ambient and public health”, financed by Fundação Calouste Gulbenkian, ref. 77161. Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2006/06 - 2006/12 Tutor at a private school Pedagonal Pedagonal, Portugal
2005/02/01 - 2005/10/31 Monitor at Escola Superio Educação do Instituto Politécnico do Porto under the project “Internet@EB1” Instituto Politécnico do Porto, Portugal
2005/02 - 2005/08 Teacher of Physics-Chemistry group 4ºA, code 15, at a public school -Escola do Ensino Básico Soares dos Reis 2º e 3º ciclos Escola do Ensino Básico Soares dos Reis 2º e 3º ciclos, Portugal
2004/08 - 2004/10 Administrative 4th level at BPI Bank (External Promoters Division). BPI, Portugal
2004/01 - 2004/03 Monitor Course (Formação Pedagógica Inicial de Formadores) at Escola Profissional de Comércio Externo, Porto Escola Profissional de Comércio Externo, Portugal
2003/01 - 2003/12 Forensic Medicine Course at National Institute of Legal Medicine and Forensic Sciences, North Branch, Porto, January - December 2003 Instituto Nacional de Medicina Legal e Ciências Forenses, Portugal
Projects

Grant

Designation Funders
2018/01/01 - 2019/08/15 IBEROS – “Instituto de BioIngeniería en Red para el Envejecimiento Saludable” (0245_IBEROS_1_E)
0245_IBEROS_1_E
Post-doc Fellow
Portuguesa Centro de Biotecnologia e Química Fina, Portugal
Concluded
2017/03/01 - 2017/12/31 NORTE-01-0145-FEDER-000012, Structured Programme on Bioengineering Therapies for Infectious Diseases and Tissue Regeneration
NORTE-01- 0145-FEDER-000012
Post-doc Fellow
Concluded
2009 - 2012 NANOFORBONE “Desenvolvimento e scale-up de estruturas 3D e material de revestimento para aplicações médicas baseadas em hidroxiapatite nanométrica", ADI-Agência de Inovação, ref. SI IDT - 5372/2008
ref. SI IDT - 5372/2008
Research Fellow

Contract

Designation Funders
2022 - Current Human Platelet Lysates-based Scaffolds for Interfacial Multi-tissue Repair
Nº 953169 (H2020-NMBP-TR-IND-2020-twostage)
Post-doc
Universidade de Aveiro Departamento de Engenharia de Materiais e Cerâmica, Portugal
Ongoing

Other

Designation Funders
2019/08/16 - 2022/02/15 Desenvolvimento de biomateriais não sinterizáveis à base de fosfatos de cálcio com bi-funcionalidade: regeneração e tratamento de cancro ósseo
29940 - Project de IC&DT – AAC n.º 02/SAICT/2017
Post-doc
Universidade de Aveiro Departamento de Engenharia de Materiais e Cerâmica, Portugal
Concluded
2007/03/01 - 2008/09/30 Bioaerossol, Poluentes não biológicos e Saúde públicaunder the Program “Ambient and public health”, financed by FCT, ref. 77161.
ref. 77161
Researcher
Concluded
Outputs

Publications

Conference poster
  1. Ribeiro, Nilza. "Multifunctional sintering-free calcium phosphate based scaffolds by 3D printing". Paper presented in 11TH WORLD BIOMATERIALS CONGRESS (WBC) 2020 Glasgow, 2020.
  2. Ribeiro, Nilza. "Biomechanics of a bone-like 3D model for bone tissue regeneration". Paper presented in AFM Biomed Conference, Porto, Portugal, 2016.
  3. Ribeiro, Nilza. "A novel biocomposite for bone regeneration". Paper presented in 4th I3S Annual Meeting, Póvoa de varzim, Portugal, 2014.
  4. Ribeiro, Nilza. "Biocomposite based on collagen nanofibers and nanohydroxyapatite functionalized with SPARC for bone regeneration". Paper presented in 3rd Advanced Summer School - Interrogations at the Biointerface – Inflammation/Repair Interface, Porto, Portugal, 2013.
  5. Ribeiro, Nilza. "3D synthetic model of collagen fibers with nanohydroxyapatite grafted with SPARC for bone regeneration and prevention of cancer related bone metastasis". Paper presented in Tissue Engineering and Regenerative Medicine International Society (TERMIS 2012) Vienna, Austria, 2012.
  6. Ribeiro, Nilza. "SPARC adsorption on nanophased hydroxyapatite and its influence on MC3T3-E1 osteoblast adhesion and morphology". Paper presented in Biological Surfaces and Interfaces conference, European Science Foundation (ESF), Sant Feliu de Guixols, Spain, 2011.
  7. Ribeiro, Nilza. "Osteonectin adsorption on nanophased hydroxyapatite and its influence on osteoblast adhesion". Paper presented in 2nd I3S Scientific Retreat, Póvoa de Varzim, Portugal, 2011.
  8. Ribeiro, Nilza. "Human Fibronectin Adsorption on Nanohydroxiapatite". Paper presented in 22nd European Conference Biomaterials, The annual conference of the European Society for Biomaterials (ESB), Lausanne, Switzerland, 2009.
  9. Ribeiro, Nilza. "Human FN adsorption onto nanohydroxyapatite and its influence on osteoblast adhesion". Paper presented in 10th Advance Summer Course in Cell-Material Interactions, Porto, Portugal, 2009.
  10. Ribeiro, Nilza. "Análisis preliminar del contenido alergénico del polen de variedades de olivo d Portugal". Paper presented in XVI International A.P.L.E Symposium of Palynology, Palma de Mallorca, Spain, 2008.
Journal article
  1. Soares, F.; Ribeiro, N.; Baião, A.; Torres, P.M.C.; Sarmento, B.; Olhero, S.M.. "Sustained drug release from sintering-free calcium phosphate-based scaffolds". Journal of Drug Delivery Science and Technology 88 (2023): 104906. http://dx.doi.org/10.1016/j.jddst.2023.104906.
    10.1016/j.jddst.2023.104906
  2. Carvalho, Tânia S.S.; Ribeiro, Nilza; Torres, Paula M.C.; Almeida, José C.; H. Belo, João; Araújo, J.P.; Ramos, António; Oliveira, Mónica; Olhero, Susana M.. "Magnetic polylactic acid-calcium phosphate-based biocomposite as a potential biomaterial for tissue engineering applications". Materials Chemistry and Physics 296 (2023): 127175. http://dx.doi.org/10.1016/j.matchemphys.2022.127175.
    10.1016/j.matchemphys.2022.127175
  3. Torres, P.M.C.; Ribeiro, N.; Nunes, Carmen; Rodrigues, A.F.M.; Sousa, A.; Olhero, S.M.. "Toughening robocast chitosan/biphasic calcium phosphate composite scaffolds with silk fibroin: Tuning printable inks and scaffold structure for bone regeneration". Materials Science and Engineering: C (2022): 112690. http://dx.doi.org/10.1016/j.msec.2022.112690.
    10.1016/j.msec.2022.112690
  4. Duarte, Marta M.; Ribeiro, Nilza; Silva, Inês V.; Dias, Juliana R.; Alves, Nuno M.; Oliveira, Ana L.. "Fast decellularization process using supercritical carbon dioxide for trabecular bone". The Journal of Supercritical Fluids 172 (2021): 105194. http://dx.doi.org/10.1016/j.supflu.2021.105194.
    10.1016/j.supflu.2021.105194
  5. Ribeiro, Nilza; Sousa, Aureliana; Cunha-Reis, Cassilda; Oliveira, Ana Leite; Granja, Pedro L.; Monteiro, Fernando J.; Sousa, Susana R.. "New prospects in skin regeneration and repair using nanophased hydroxyapatite embedded in collagen nanofibers". Nanomedicine: Nanotechnology, Biology and Medicine 33 (2021): 102353. http://dx.doi.org/10.1016/j.nano.2020.102353.
    10.1016/j.nano.2020.102353
  6. Rodrigues, A F M; Torres, P M C; Barros, M J S; Presa, R; Ribeiro, N; Abrantes, J C C; Belo, J H; et al. "Effective production of multifunctional magnetic-sensitive biomaterial by an extrusion-based additive manufacturing technique". Biomedical Materials 16 1 (2020): 015011. http://dx.doi.org/10.1088/1748-605x/abac4c.
    10.1088/1748-605x/abac4c
  7. Dias, Juliana R.; Ribeiro, Nilza; Baptista-Silva, Sara; Costa-Pinto, Ana Rita; Alves, Nuno; Oliveira, Ana L.. "In situ Enabling Approaches for Tissue Regeneration: Current Challenges and New Developments". Frontiers in Bioengineering and Biotechnology 8 (2020): http://dx.doi.org/10.3389/fbioe.2020.00085.
    10.3389/fbioe.2020.00085
  8. de Siqueira, Lilian; Ribeiro, Nilza; Paredes, Maria B. A.; Grenho, Liliana; Cunha-Reis, Cassilda; Trichês, Eliandra S.; Fernandes, Maria H.; Sousa, Susana R.; Monteiro, Fernando J.. "Influence of PLLA/PCL/HA Scaffold Fiber Orientation on Mechanical Properties and Osteoblast Behavior". Materials 12 23 (2019): 3879. http://dx.doi.org/10.3390/ma12233879.
    10.3390/ma12233879
  9. Ribeiro, Nilza; Soares, Gonçalo C.; Santos-Rosales, Víctor; Concheiro, Angel; Alvarez-Lorenzo, Carmen; García-González, Carlos A.; Oliveira, Ana L.. "A new era for sterilization based on supercritical CO 2 technology". Journal of Biomedical Materials Research Part B: Applied Biomaterials 108 2 (2019): 399-428. http://dx.doi.org/10.1002/jbm.b.34398.
    10.1002/jbm.b.34398
  10. Santos-Rosales, Víctor; Ardao, Inés; Alvarez-Lorenzo, Carmen; Ribeiro, Nilza; Oliveira, Ana; García-González, Carlos. "Sterile and Dual-Porous Aerogels Scaffolds Obtained through a Multistep Supercritical CO2-Based Approach". Molecules 24 5 (2019): 871. http://dx.doi.org/10.3390/molecules24050871.
    10.3390/molecules24050871
  11. Cruz-Neves, Susana; Ribeiro, Nilza; Graça, Inês; Jerónimo, Carmen; Sousa, Susana R.; Monteiro, Fernando J.. "Behavior of prostate cancer cells in a nanohydroxyapatite/collagen bone scaffold". Journal of Biomedical Materials Research Part A 105 7 (2017): 2035-2046. http://dx.doi.org/10.1002/jbm.a.36070.
    10.1002/jbm.a.36070
  12. Silva, Patrícia M.A.; Ribeiro, Nilza; Lima, Raquel T.; Andrade, Cláudia; Diogo, Vânia; Teixeira, Joana; Florindo, Cláudia; et al. "Suppression of spindly delays mitotic exit and exacerbates cell death response of cancer cells treated with low doses of paclitaxel". Cancer Letters 394 (2017): 33-42. http://dx.doi.org/10.1016/j.canlet.2017.02.024.
    10.1016/j.canlet.2017.02.024
  13. Ribeiro, Nilza; Costa-Pinheiro, Pedro; Henrique, Rui; Gomez-Lazaro, Maria; Pereira, Marisa P.; Mansur, Alexandra A. P.; Mansur, Herman S.; et al. "Comprehensive Analysis of Secreted Protein, Acidic and Rich in Cysteine in Prostate Carcinogenesis: Development of a 3D Nanostructured Bone-Like Model". Journal of Biomedical Nanotechnology 12 8 (2016): 1667-1678. http://dx.doi.org/10.1166/jbn.2016.2276.
    10.1166/jbn.2016.2276
  14. Ribeiro, Nilza; Sousa, Susana R; van Blitterswijk, Clemens A; Moroni, Lorenzo; Monteiro, Fernando J. "A biocomposite of collagen nanofibers and nanohydroxyapatite for bone regeneration". Biofabrication 6 3 (2014): 035015. http://dx.doi.org/10.1088/1758-5082/6/3/035015.
    10.1088/1758-5082/6/3/035015
  15. Ribeiro, Nilza; Sousa, Susana R.; Brekken, Rolf A.; Monteiro, Fernado J.. "Role of SPARC in Bone Remodeling and Cancer-Related Bone Metastasis". Journal of Cellular Biochemistry 115 1 (2013): 17-26. http://dx.doi.org/10.1002/jcb.24649.
    10.1002/jcb.24649
  16. Ribeiro, N.; Sousa, S.R.; Monteiro, F.J.. "Influence of crystallite size of nanophased hydroxyapatite on fibronectin and osteonectin adsorption and on MC3T3-E1 osteoblast adhesion and morphology". Journal of Colloid and Interface Science 351 2 (2010): 398-406. http://dx.doi.org/10.1016/j.jcis.2010.08.013.
    10.1016/j.jcis.2010.08.013
  17. Ribeiro, H.; Oliveira, M.; Ribeiro, N.; Cruz, A.; Ferreira, A.; Machado, H.; Reis, A.; Abreu, I.. "Pollen allergenic potential nature of some trees species: A multidisciplinary approach using aerobiological, immunochemical and hospital admissions data". Environmental Research 109 3 (2009): 328-333. http://dx.doi.org/10.1016/j.envres.2008.11.008.
    10.1016/j.envres.2008.11.008
  18. Guedes, A.; Ribeiro, N.; Ribeiro, H.; Oliveira, M.; Noronha, F.; Abreu, I.. "Comparison between urban and rural pollen of Chenopodium alba and characterization of adhered pollutant aerosol particles". Journal of Aerosol Science 40 1 (2009): 81-86. http://dx.doi.org/10.1016/j.jaerosci.2008.07.012.
    10.1016/j.jaerosci.2008.07.012
  19. Abreu, Ilda; Ribeiro, Nilza; Ribeiro, Helena; Oliveira, Manuela; Cruz, Ana. "Airborne Poaceae pollen in Porto (Portugal) and allergenic profiles of several grass pollen types". Aerobiologia 24 3 (2008): 133-140. http://dx.doi.org/10.1007/s10453-008-9093-3.
    10.1007/s10453-008-9093-3
Thesis / Dissertation
  1. Ribeiro, Nilza. "SPARC grafted on a 3D synthetic model (collagen/nanohydroxyapatite) and its effect on bone regeneration and cancer related bone metastasis". PhD, Universidade do Porto Faculdade de Engenharia, 2016.
  2. Ribeiro, Nilza. "Fibronectin and osteonectin adsorption onto hydroxyapatite nanostructures and its influence on osteoblast adhesion". Master, Universidade do Porto Faculdade de Engenharia, 2009.

Intellectual property

Patent
  1. Ribeiro, Nilza. 2015. "mesh composition for repairing or the regeneration of tissues and methods thereof". Portugal.
    Expired
Provisional application for patent
  1. 2021. "Pasta magnética compreendendo pó biocerâmico magnético para manufatura aditiva por técnicas de extrusão".
    Protected
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2019/07/02 Innovation Research at the Biomaterials and Biomedical Technology Lab within the IBEROS project VII Jornada Científica IBEROS, Guimarães
IBEROS (Guimarães, Portugal)
2019/03/29 Effectiveness of terminal sterilization of bacterial spores using the supercritical carbon dioxide technology VI Jornada Científica IBEROS
IBEROS (Porto)
2018/11/14 Uma nova era de esterilização na área biomédica Conferências em Biotecnologia, ESB Católica Porto,
ESB Católica Porto, (Porto)
2018/03/19 Supercritical carbon dioxide as an alternative for terminal sterilization of thermolabile and hydrolytically sensitive biomaterials III Jornada Científica IBEROS
IBEROS (Porto)
2017/11 3D nanostructured bone-like biocomposites focused in tissue regeneration and as a model support for studying cancer related bone metastasis i3S Annual Meeting
i3S (Póvoa do Varzim)
2017/08 3D nanostructured bone-like biocomposites focus in tissue regeneration and as a model support for studying cancer related bone metastasis 3rd Global Nanotechnology Congress and Expo
Global Nanotechnology Congress and Expo (Dallas, United States)
2017/05 3D nanostructured bone-like biocomposites focus in tissue regeneration and as a model support for studying cancer related bone metastasis Seminar at i3S - Host interaction and response
i3S (Porto)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2021/03 - 2021/07 Otimização de uma formulação de matriz polimérica para desenvolvimento de um material injetável para regeneração óssea
Supervisor
 Materials Engineering (Master)
Universidade de Aveiro, Portugal
2021/03 - 2021/07 Estruturas porosas 3D à base de fosfatos de cálcio para tratamento localizado de cancro ósseo por hipertermia
Supervisor
 Biomedical Engineering (Master)
Universidade de Aveiro, Portugal
2018/09 - 2019/09 Sterilization of a Blood Derivative Using Supercritical Carbon Dioxide (scCO2)
Supervisor
 Engenharia Biomédica (Master)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2018/09 - 2019/09 New Strategies For The Decellularization Of Biological Tissues
Co-supervisor
 Engenharia Biomédica (Master)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2018/01 - 2019/01 Terminal Sterilization Using Supercritical Carbon Dioxide (scCO2): Influence of Several Processing Parameters
Co-supervisor
 Engenharia do Ambiente (Master)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2019/09 The role of Sparc derived peptides on cell culture of endothelial cells and prostate cancer cells
(Thesis) Main arguer
 Luisamaria Castañeda Matiz (Other)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/07 Optimization of the handling properties of PVA-reinforced calcium phosphate cement for minimally invasive vertebroplasty and kyphoplasty
(Thesis) Main arguer
 João de Castro Pinto (Master)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2018/07 Role of Sparc and peptide 2.3 on endothelial and prostate cancer cells
(Thesis) Main arguer
 Ana Sofia Sousa (Other)
Universidade do Porto Departamento de Química e Bioquímica, Portugal
2018/03 Biocompatible silk-fibroin electrospun matrices for in vitro cell culture
(Thesis) Main arguer
 Carolina Teixeira Paredes (Master)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências e Tecnologia, Portugal
Distinctions

Other distinction

2016 Best poster award in AFMBiomed 2016 Conference, Porto, Portugal, April 2016.
2014 Top three best ideas at BES (Banco Espírito Santo) Innovation contest (June 2013) with the product developed during her PhD training and published in Biofabrication journal (2014).