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Ruben Valente has graduated in Biochemistry in 2019 by NOVA School of Science and Technology | FCT-NOVA, and has recently completed the MSc in Biotechnology by the same institution. His main scientific interests include in biomedicine, biotechnology, nanomedicine and nanotechnology.
Identification

Personal identification

Full name
Ruben Valente

Citation names

  • Valente, Ruben

Author identifiers

Ciência ID
AD16-46C3-AE81
ORCID iD
0000-0001-6534-4128

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Education
Degree Classification
2023/02/01 - 2027/01/01
Ongoing
 Biotecnologia (Doutoramento)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/09 - 2022/02/08
Concluded
 Biotecnologia (Mestrado)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Modulation of Tumor Microenvironment towards cancer therapy" (THESIS/DISSERTATION)
 18 (0-20)
2016/09 - 2019/07
Concluded
 Bioquímica (Licenciatura)
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
"Caracterização do potencial anti-tumoral de novos compostos para o tratamento do cancro" (THESIS/DISSERTATION)
 16 (0-20)
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2020/10 - 2021/07 Tutor (University Teacher) Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Universidade Nova de Lisboa Departamento de Química, Portugal

Others

Category
Host institution 		Employer
2022/02 - 2022/07 Volunteer Internship as Research Assistant Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021/10 - 2022/05 Member of External Assessment Teams Agência de Avaliação e Acreditação do Ensino Superior (A3ES), Portugal
2020/09 - 2022/02 Master thesis in Biotechnology Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019/01 - 2019/07 Internship as Research Assistant Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2017/07/01 - 2017/08/31 Summer Internship as Research Assistant Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
Projects

Grant

Designation Funders
2023/02/01 - Current Au-NANOconjugates for combinatory therapeutics against PDAC - bridging the translation gap between 3D and PDOs
2022.09845.BD
PhD Student Fellow
Unidade de Ciências Biomoleculares Aplicadas, Portugal

Universitair Medisch Centrum Groningen, Netherlands
Fundação para a Ciência e a Tecnologia
Ongoing
Outputs

Publications

Conference poster
  1. Valente, Ruben. "Colorectal cancer spheroid models: exploring tumor microenvironment dynamics and response to treatment". Paper presented in 6th ASPIC International Congress, 2024.
Journal article
  1. Sandra Cordeiro; Beatriz B. Oliveira; Ruben Valente; Daniela Ferreira; André Luz; Pedro V. Baptista; Alexandra R. Fernandes. "Breaking the mold: 3D cell cultures reshaping the future of cancer research". Frontiers in Cell and Developmental Biology (2024): http://dx.doi.org/10.3389/fcell.2024.1507388.
    10.3389/fcell.2024.1507388
  2. Ruben Valente; Sandra Cordeiro; André Luz; Maria C. Melo; Catarina Roma Rodrigues; Pedro V. Baptista; Alexandra R. Fernandes. "Doxorubicin-sensitive and -resistant colorectal cancer spheroid models: assessing tumor microenvironment features for therapeutic modulation". Frontiers in Cell and Developmental Biology (2023): http://dx.doi.org/10.3389/fcell.2023.1310397.
    10.3389/fcell.2023.1310397
  3. Filipe Magalhães; Claúdia Andrade; Beatriz Simões; Fredi Brigham; Ruben Valente; Pedro Martinez; José Rino; Michela Sugni; Ana Coelho. "Regeneration of starfish radial nerve cord restores animal mobility and unveils a new coelomocyte population". Cell and Tissue Research (2023): http://dx.doi.org/10.1007/s00441-023-03818-x.
    10.1007/s00441-023-03818-x
  4. Ana F. Amendoeira; André Luz; Ruben Valente; Catarina Roma-Rodrigues; Hasrat Ali; Johan E. van Lier; Fernanda Marques; Pedro V. Baptista; Alexandra R. Fernandes. "Cell Uptake of Steroid-BODIPY Conjugates and Their Internalization Mechanisms: Cancer Theranostic Dyes". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24043600.
    Published • 10.3390/ijms24043600
  5. Roma-Rodrigues, Catarina; Raposo, Luís; Valente, Ruben; Alexandra R Fernandes; Baptista, Pedro. Corresponding author: Baptista, Pedro. "Combined cancer therapeutics - Tackling the complexity of the tumor microenvironment". WIREs Nanomedicine and Nanobiotechnology n/a n/a (2021): e1704-e1704. https://onlinelibrary.wiley.com/doi/abs/10.1002/wnan.1704.
    https://doi.org/10.1002/wnan.1704
  6. Diogo Sequeira; Pedro V. Baptista; Ruben Valente; M. Fátima M. Piedade; M. Helena Garcia; Tânia S. Morais; Alexandra R. Fernandes. "Cu(i) complexes as new antiproliferative agents against sensitive and doxorubicin resistant colorectal cancer cells: synthesis, characterization, and mechanisms of action". Dalton Transactions (2021): https://doi.org/10.1039/D0DT03566A.
    10.1039/D0DT03566A
Thesis / Dissertation
  1. "Modulation of tumor microenvironment towards cancer therapy". Master, Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, 2022. http://hdl.handle.net/10362/133077.
  2. "Caracterização do potencial anti-tumoral de novos compostos para o tratamento do cancro". Degree, Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, 2019.
Activities

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2019 - 2020 Jornadas Tecnológicas de Bioquímica 2020 - 15 anos de Bioquímica (2020/02/08)
Conference (President of the Organising Committee)
 Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2018 - 2019 Jornadas Tecnológicas de Bioquímica 2019 - Biomedicina: Doenças Emergentes (2019/02/08)
Conference (President of the Organising Committee)
 Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2017 - 2018 Jornadas Tecnológicas de Bioquímica 2018 - Bioquímica: Da investigação à indústria (2018/02/02)
Conference (Member of the Organising Committee)
 Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Association member

Society Organization name Role
2023/02/06 - Current Associação Portuguesa de Investigação em Cancro
2019/01/01 - 2019/12/31 FCT-NOVA Students' Union - AEFCT Member of the Fiscal Council

Committee member

Activity description
Role 		Institution / Organization
2019/10 - 2020/11 Pedagogic committee of the MSc in Biotechnology
President / Vice-president
2019/01 - 2020/10 Pedagogical Council of FCT-NOVA - Representative of Chemistry Department students
Member
 Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2017/11 - 2019/10 Pedagogic Committee of the BSc in Biochemistry
President / Vice-president
 Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
Distinctions

Title

2022 MSc in Biotechnology
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2019 BSc in Biochemistry
Universidade NOVA de Lisboa Faculdade de Ciências e Tecnologia, Portugal